Mga Batayang Estadistika
Nilai Portofolio $ 94,485,749
Posisi Saat Ini 169
Kepemilikan Terbaru, Kinerja, AUM (dari 13F, 13D)

John Hancock Funds II - Health Sciences Fund Class NAV telah mengungkapkan total kepemilikan 169 dalam pengajuan SEC terbaru mereka. Nilai portofolio terbaru dihitung sebesar $ 94,485,749 USD. Aset yang Dikelola (AUM) sebenarnya adalah nilai ini ditambah kas (yang tidak diungkapkan). Aset-aset utama John Hancock Funds II - Health Sciences Fund Class NAV adalah Eli Lilly and Company (US:LLY) , Intuitive Surgical, Inc. (US:ISRG) , UnitedHealth Group Incorporated (US:UNH) , Thermo Fisher Scientific Inc. (US:TMO) , and Stryker Corporation (US:SYK) . Posisi baru John Hancock Funds II - Health Sciences Fund Class NAV meliputi: Gilead Sciences, Inc. (US:GILD) , CVS Health Corporation (US:CVS) , Metsera, Inc. (US:MTSR) , Sionna Therapeutics, Inc. (US:SION) , and Beta Bionics, Inc. (US:BBNX) .

Peningkatan Tertinggi Kuartal Ini

Kami menggunakan perubahan dalam alokasi portofolio karena ini adalah metrik yang paling bermakna. Perubahan dapat disebabkan oleh perdagangan atau perubahan harga saham.

Keamanan Saham
(MM)
Nilai
(Juta Dolar AS)
Portfolio % ΔPorsyento ng Portfolio
0.01 10.58 11.1936 1.8237
0.03 2.96 3.1366 0.8272
0.01 5.90 6.2387 0.8162
0.01 0.65 0.6869 0.6869
0.01 3.00 3.1739 0.6788
0.01 1.54 1.6255 0.5010
0.01 4.45 4.7079 0.4986
0.01 0.78 0.8245 0.4638
0.02 0.87 0.9193 0.4330
0.05 0.96 1.0204 0.3849
Penurunan Tertinggi Kuartal Ini

Kami menggunakan perubahan dalam alokasi portofolio karena ini adalah metrik yang paling bermakna. Perubahan dapat disebabkan oleh perdagangan atau perubahan harga saham.

Keamanan Saham
(MM)
Nilai
(Juta Dolar AS)
Portfolio % ΔPorsyento ng Portfolio
0.01 5.18 5.4779 -2.9886
0.02 1.51 1.5945 -0.8485
0.00 0.00 -0.6752
0.01 2.71 2.8679 -0.6638
0.00 1.36 1.4363 -0.2854
0.01 0.31 0.3255 -0.2592
0.00 1.75 1.8487 -0.2562
0.00 1.42 1.4975 -0.2514
0.01 0.54 0.5672 -0.2078
0.00 0.50 0.5255 -0.2060
Pengajuan 13F dan Dana

Formulir ini diajukan pada 2025-04-28 untuk periode pelaporan 2025-02-28. Klik ikon tautan untuk melihat riwayat transaksi selengkapnya.

Tingkatkan ke versi premium untuk membuka data premium dan ekspor ke Excel. .

2022-07-28: Catatan Penting - Kami telah mengubah cara perhitungan kolom Δ Portfolio % pada tabel ini. Sebelumnya, kami melaporkannya sebagai persentase perubahan dalam alokasi portofolio. Sekarang kami melaporkannya sebagai perubahan mentah dalam alokasi portofolio (tetap dilaporkan sebagai persentase). Dalam rumus, sebelumnya kami melaporkannya sebagai 100 * (alokasi saat ini - alokasi sebelumnya) / alokasi sebelumnya. Sekarang kami melaporkannya sebagai (alokasi saat ini - alokasi sebelumnya).
Keamanan Ketik Harga Saham Rata-rata Saham
(MM)
ΔSaham
(%)
ΔSaham
(%)
Nilai
($MM)
Portpolyo
(%)
ΔPortofolio
(%)
LLY / Eli Lilly and Company 0.01 -57.05 10.58 -50.28 11.1936 1.8237
ISRG / Intuitive Surgical, Inc. 0.01 -54.72 5.90 -52.12 6.2387 0.8162
UNH / UnitedHealth Group Incorporated 0.01 -65.40 5.18 -73.07 5.4779 -2.9886
TMO / Thermo Fisher Scientific Inc. 0.01 -53.39 4.45 -53.45 4.7079 0.4986
SYK / Stryker Corporation 0.01 -54.15 4.20 -54.85 4.4484 0.3481
ARGX / argenx SE - Depositary Receipt (Common Stock) 0.01 -54.97 3.48 -54.38 3.6829 0.3232
VRTX / Vertex Pharmaceuticals Incorporated 0.01 -48.34 3.00 -47.05 3.1739 0.6788
BSX / Boston Scientific Corporation 0.03 -50.62 2.96 -43.48 3.1366 0.8272
DHR / Danaher Corporation 0.01 -61.01 2.71 -66.21 2.8679 -0.6638
ALNY / Alnylam Pharmaceuticals, Inc. 0.01 -53.24 2.30 -54.42 2.4358 0.2120
AZN / AstraZeneca PLC - Depositary Receipt (Common Stock) 0.03 -56.45 2.18 -50.93 2.3060 0.3505
ANTM / Anthem Inc 0.00 -62.52 1.75 -63.45 1.8487 -0.2562
REGN / Regeneron Pharmaceuticals, Inc. 0.00 -57.94 1.59 -60.82 1.6854 -0.1053
INSM / Insmed Incorporated 0.02 -53.81 1.56 -49.89 1.6478 0.2795
ONC / BeOne Medicines AG - Depositary Receipt (Common Stock) 0.01 -52.41 1.54 -39.84 1.6255 0.5010
MRK / Merck & Co., Inc. 0.02 -70.07 1.51 -72.84 1.5945 -0.8485
AMGN / Amgen Inc. 0.00 -67.28 1.42 -64.38 1.4975 -0.2514
CI / The Cigna Group 0.00 -62.02 1.36 -65.29 1.4363 -0.2854
PEN / Penumbra, Inc. 0.00 -52.08 1.31 -43.99 1.3857 0.3563
BPMC / Blueprint Medicines Corporation 0.01 -56.75 1.15 -56.66 1.2156 0.0482
ASND / Ascendis Pharma A/S - Depositary Receipt (Common Stock) 0.01 -58.23 1.01 -51.95 1.0712 0.1436
SMMT / Summit Therapeutics Inc. 0.05 -40.37 0.96 -33.19 1.0204 0.3849
SNY / Sanofi - Depositary Receipt (Common Stock) 0.02 -52.46 0.96 -46.64 1.0166 0.2243
BDX / Becton, Dickinson and Company 0.00 -64.88 0.88 -64.29 0.9279 -0.1539
CHGCF / Chugai Pharmaceutical Co., Ltd. 0.02 -31.08 0.87 -21.29 0.9193 0.4330
VRNA / Verona Pharma plc - Depositary Receipt (Common Stock) 0.01 -45.85 0.78 -4.88 0.8245 0.4638
HCA / HCA Healthcare, Inc. 0.00 -56.92 0.71 -59.69 0.7508 -0.0240
SONVY / Sonova Holding AG - Depositary Receipt (Common Stock) 0.00 -35.04 0.71 -38.86 0.7494 0.2391
RHHBY / Roche Holding AG - Depositary Receipt (Common Stock) 0.00 -52.49 0.68 -46.07 0.7184 0.2437
GILD / Gilead Sciences, Inc. 0.01 0.65 0.6869 0.6869
NTRA / Natera, Inc. 0.00 -50.64 0.65 -54.29 0.6833 0.0620
SRRK / Scholar Rock Holding Corporation 0.02 -50.94 0.62 -52.30 0.6600 0.0845
MOH / Molina Healthcare, Inc. 0.00 -60.97 0.61 -60.60 0.6441 -0.0355
THC / Tenet Healthcare Corporation 0.00 -58.46 0.60 -63.17 0.6365 -0.0823
RNA / Avidity Biosciences, Inc. 0.02 -56.12 0.57 -68.79 0.6062 -0.2012
NBIX / Neurocrine Biosciences, Inc. 0.00 -47.88 0.56 -51.18 0.5895 0.0869
PCVX / Vaxcyte, Inc. 0.01 -60.65 0.54 -69.55 0.5672 -0.2078
RVMD / Revolution Medicines, Inc. 0.01 -50.13 0.53 -64.92 0.5605 -0.1037
DGX / Quest Diagnostics Incorporated 0.00 -39.68 0.53 -35.92 0.5592 0.1962
ZLAB / Zai Lab Limited - Depositary Receipt (Common Stock) 0.02 -51.81 0.52 -42.15 0.5537 0.1554
IDXX / IDEXX Laboratories, Inc. 0.00 -39.67 0.52 -37.48 0.5470 0.1829
SOAGY / Sartorius Aktiengesellschaft - Depositary Receipt (Common Stock) 0.00 -14.44 0.50 -7.18 0.5342 0.2948
BHVN / Biohaven Ltd. 0.01 -57.34 0.50 -65.58 0.5268 -0.1092
UTHR / United Therapeutics Corporation 0.00 -65.39 0.50 -70.14 0.5255 -0.2060
AKRO / Akero Therapeutics, Inc. 0.01 -42.43 0.47 -12.03 0.4962 0.2618
MLTX / MoonLake Immunotherapeutics 0.01 -53.11 0.46 -64.02 0.4900 -0.0769
EXAS / Exact Sciences Corporation 0.01 -53.01 0.43 -64.18 0.4528 -0.0724
ACLX / Arcellx, Inc. 0.01 -55.28 0.42 -67.09 0.4402 -0.1165
CNTA / Centessa Pharmaceuticals plc - Depositary Receipt (Common Stock) 0.03 -50.51 0.41 -57.04 0.4363 0.0137
CAH / Cardinal Health, Inc. 0.00 -48.97 0.41 -45.93 0.4287 0.0986
CNC / Centene Corporation 0.01 -37.53 0.39 -39.56 0.4082 0.1276
PKI / Revvity Inc. 0.00 -52.45 0.36 -54.05 0.3841 0.0360
KRYS / Krystal Biotech, Inc. 0.00 -44.75 0.36 -49.86 0.3812 0.0649
A / Agilent Technologies, Inc. 0.00 -66.26 0.36 -68.77 0.3776 -0.1248
CVS / CVS Health Corporation 0.01 0.35 0.3736 0.3736
ALKS / Alkermes plc 0.01 -52.22 0.35 -43.53 0.3701 0.0975
MDGL / Madrigal Pharmaceuticals, Inc. 0.00 -64.14 0.35 -62.70 0.3683 -0.0427
TECH / Bio-Techne Corporation 0.01 -56.61 0.35 -64.47 0.3654 -0.0623
RARE / Ultragenyx Pharmaceutical Inc. 0.01 -40.08 0.33 -46.04 0.3464 0.0794
MASI / Masimo Corporation 0.00 98.13 0.32 200.94 0.3379 0.2982
VEEV / Veeva Systems Inc. 0.00 -11.32 0.32 14.03 0.3362 0.2323
DXCM / DexCom, Inc. 0.00 -48.78 0.32 -41.99 0.3338 0.0944
SWTX / SpringWorks Therapeutics, Inc. 0.01 -63.85 0.31 -49.76 0.3330 0.0577
COR / Cencora, Inc. 0.00 -58.47 0.31 -58.22 0.3288 0.0019
AGIO / Agios Pharmaceuticals, Inc. 0.01 -61.28 0.31 -76.87 0.3255 -0.2592
PTGX / Protagonist Therapeutics, Inc. 0.01 -53.02 0.30 -59.79 0.3183 -0.0102
KYMR / Kymera Therapeutics, Inc. 0.01 -55.47 0.30 -70.29 0.3131 -0.1242
OSCR / Oscar Health, Inc. 0.02 -62.29 0.29 -68.28 0.3067 -0.0948
MCK / McKesson Corporation 0.00 -59.32 0.29 -58.60 0.3062 -0.0013
BTSG / BrightSpring Health Services, Inc. 0.01 -57.06 0.29 -57.08 0.3047 0.0091
RGEN / Repligen Corporation 0.00 -58.20 0.29 -55.81 0.3018 0.0177
VERA / Vera Therapeutics, Inc. 0.01 -51.85 0.28 -71.06 0.2978 -0.1301
CRNX / Crinetics Pharmaceuticals, Inc. 0.01 -60.88 0.27 -75.56 0.2904 -0.2036
BEAM / Beam Therapeutics Inc. 0.01 -50.16 0.25 -52.20 0.2655 0.0351
INCY / Incyte Corporation 0.00 -64.34 0.24 -64.96 0.2549 -0.0470
IMCR / Immunocore Holdings plc - Depositary Receipt (Common Stock) 0.01 -57.17 0.24 -61.65 0.2513 -0.0209
PRCT / PROCEPT BioRobotics Corporation 0.00 -51.51 0.24 -67.45 0.2495 -0.0687
DNLI / Denali Therapeutics Inc. 0.01 -48.48 0.23 -65.84 0.2465 -0.0541
IMMUNOCORE HOLDINGS PLC SR UNSECURED 02/30 2.5 / DBT (US45258DAB10) 0.23 0.2449 0.2449
COO / The Cooper Companies, Inc. 0.00 -50.87 0.23 -57.49 0.2406 0.0050
UCBJY / UCB SA - Depositary Receipt (Common Stock) 0.00 -24.91 0.20 -27.76 0.2157 0.0916
EW / Edwards Lifesciences Corporation 0.00 -79.76 0.18 -79.69 0.1948 -0.2043
IMNM / Immunome, Inc. 0.02 -44.23 0.18 -61.51 0.1904 -0.0144
HLXB / Helix Acquisition Corp. II 0.02 0.00 0.18 6.55 0.1896 0.1153
BIIB / Biogen Inc. 0.00 -56.05 0.18 -61.64 0.1891 -0.0156
REPL / Replimune Group, Inc. 0.01 -56.37 0.18 -60.67 0.1874 -0.0111
LEGN / Legend Biotech Corporation - Depositary Receipt (Common Stock) 0.00 -60.15 0.17 -66.86 0.1843 -0.0470
LNTH / Lantheus Holdings, Inc. 0.00 -58.53 0.17 -56.59 0.1787 0.0080
ALHC / Alignment Healthcare, Inc. 0.01 -62.64 0.16 -53.54 0.1738 0.0182
CYTK / Cytokinetics, Incorporated 0.00 -78.53 0.16 -80.96 0.1716 -0.2034
APGE / Apogee Therapeutics, Inc. 0.01 -50.05 0.16 -65.34 0.1669 -0.0328
NUVL / Nuvalent, Inc. 0.00 -56.96 0.16 -66.67 0.1655 -0.0409
IONS / Ionis Pharmaceuticals, Inc. 0.00 -71.96 0.15 -74.02 0.1614 -0.0965
IRON / Disc Medicine, Inc. 0.00 -53.10 0.15 -58.64 0.1555 -0.0004
JANX / Janux Therapeutics, Inc. 0.00 -50.99 0.13 -64.43 0.1347 -0.0225
MTSR / Metsera, Inc. 0.00 0.12 0.1237 0.1237
MRUS / Merus N.V. 0.00 -67.95 0.12 -66.38 0.1229 -0.0291
ICLR / ICON Public Limited Company 0.00 -73.74 0.12 -76.43 0.1226 -0.0924
BCYC / Bicycle Therapeutics plc - Depositary Receipt (Common Stock) 0.01 -54.35 0.12 -75.58 0.1225 -0.0852
WVE / Wave Life Sciences Ltd. 0.01 -68.28 0.11 -77.82 0.1207 -0.1056
RYTM / Rhythm Pharmaceuticals, Inc. 0.00 -64.38 0.11 -68.70 0.1205 -0.0386
TARS / Tarsus Pharmaceuticals, Inc. 0.00 -54.46 0.11 -61.59 0.1181 -0.0092
CLDX / Celldex Therapeutics, Inc. 0.01 -58.75 0.11 -69.16 0.1137 -0.0393
CGON / CG Oncology, Inc. 0.00 -51.76 0.10 -64.26 0.1055 -0.0168
ALSEN / Sensorion SA 0.16 -14.33 0.10 -27.07 0.1030 0.0444
WGS / GeneDx Holdings Corp. 0.00 -9.70 0.09 18.18 0.0973 0.0631
PRAX / Praxis Precision Medicines, Inc. 0.00 -61.10 0.09 -81.31 0.0967 -0.1182
XNCR / Xencor, Inc. 0.01 -63.49 0.09 -78.29 0.0951 -0.0856
BCAX / Bicara Therapeutics Inc. 0.01 -26.86 0.09 -53.51 0.0920 0.0102
MBX / MBX Biosciences, Inc. 0.01 0.00 0.09 -53.01 0.0918 0.0108
RCKT / Rocket Pharmaceuticals, Inc. 0.01 -53.62 0.09 -69.86 0.0909 -0.0333
SLNO / Soleno Therapeutics, Inc. 0.00 -79.40 0.09 -81.03 0.0905 -0.1069
SION / Sionna Therapeutics, Inc. 0.01 0.08 0.0860 0.0860
ORIC / ORIC Pharmaceuticals, Inc. 0.01 -52.21 0.08 -61.58 0.0836 -0.0062
ARVN / Arvinas, Inc. 0.00 -46.60 0.08 -64.84 0.0820 -0.0145
PRTA / Prothena Corporation plc 0.00 -58.41 0.08 -59.47 0.0818 -0.0021
NVCR / NovoCure Limited 0.00 -84.97 0.08 -85.71 0.0816 -0.1558
BNTX / BioNTech SE - Depositary Receipt (Common Stock) 0.00 -83.92 0.08 -84.71 0.0806 -0.1382
PHVS / Pharvaris N.V. 0.00 -41.27 0.08 -57.63 0.0800 0.0019
GPCR / Structure Therapeutics Inc. - Depositary Receipt (Common Stock) 0.00 -73.89 0.07 -81.38 0.0776 -0.0951
EWTX / Edgewise Therapeutics, Inc. 0.00 0.07 0.0775 0.0775
BBNX / Beta Bionics, Inc. 0.00 0.07 0.0744 0.0744
EHC / Encompass Health Corporation 0.00 -36.73 0.07 -38.94 0.0737 0.0239
RAPP / Rapport Therapeutics, Inc. 0.01 -60.38 0.06 -82.66 0.0680 -0.0947
ALLO / Allogene Therapeutics, Inc. 0.03 -59.74 0.06 -68.32 0.0678 -0.0213
GLUE / Monte Rosa Therapeutics, Inc. 0.01 -69.75 0.06 -83.93 0.0667 -0.1061
SYRE / Spyre Therapeutics, Inc. 0.00 -53.72 0.06 -67.89 0.0646 -0.0193
SANA / Sana Biotechnology, Inc. 0.02 -52.31 0.06 -55.81 0.0612 0.0043
IOVA / Iovance Biotherapeutics, Inc. 0.01 -50.99 0.06 -77.87 0.0597 -0.0519
LENZ / LENZ Therapeutics, Inc. 0.00 -78.84 0.06 -87.12 0.0586 -0.1295
AURA / Aura Biosciences, Inc. 0.01 -37.31 0.06 -49.54 0.0584 0.0102
TXG / 10x Genomics, Inc. 0.01 -74.34 0.05 -82.86 0.0576 -0.0813
VRDN / Viridian Therapeutics, Inc. 0.00 -3.58 0.05 -31.17 0.0570 0.0229
RLAY / Relay Therapeutics, Inc. 0.02 -43.73 0.05 -59.52 0.0546 -0.0011
HIMS / Hims & Hers Health, Inc. 0.00 0.05 0.0531 0.0531
IDYA / IDEAYA Biosciences, Inc. 0.00 -73.09 0.05 -79.76 0.0531 -0.0561
EYPT / EyePoint Pharmaceuticals, Inc. 0.01 -46.91 0.05 -62.88 0.0526 -0.0056
ORKA / Oruka Therapeutics, Inc. 0.00 -43.62 0.05 -73.89 0.0502 -0.0291
LYEL / Lyell Immunopharma, Inc. 0.07 -53.10 0.05 -64.89 0.0490 -0.0088
HRTX / Heron Therapeutics, Inc. 0.02 0.05 0.0483 0.0483
URGN / UroGen Pharma Ltd. 0.00 0.00 0.04 -25.42 0.0470 0.0208
VYGR / Voyager Therapeutics, Inc. 0.01 -51.33 0.04 -71.43 0.0452 -0.0198
TRDA / Entrada Therapeutics, Inc. 0.00 -55.88 0.04 -73.75 0.0451 -0.0257
OCUL / Ocular Therapeutix, Inc. 0.01 -62.05 0.04 -72.85 0.0439 -0.0228
SEPN / Septerna, Inc. 0.01 -4.63 0.04 -75.46 0.0423 -0.0299
KOD / Kodiak Sciences Inc. 0.01 -34.95 0.04 -60.20 0.0416 -0.0016
OBIO / Orchestra BioMed Holdings, Inc. 0.01 -35.20 0.04 -47.14 0.0402 0.0092
APLS / Apellis Pharmaceuticals, Inc. 0.00 -74.12 0.04 -80.83 0.0392 -0.0459
PACB / Pacific Biosciences of California, Inc. 0.03 -31.29 0.04 -48.57 0.0389 0.0079
CGEM / Cullinan Therapeutics, Inc. 0.00 -43.01 0.04 -83.71 0.0382 -0.0106
NGNE / Neurogene Inc. 0.00 0.00 0.04 -30.00 0.0374 0.0150
ANNX / Annexon, Inc. 0.01 -44.41 0.03 -73.17 0.0356 -0.0188
IMRX / Immuneering Corporation 0.02 -39.92 0.03 -52.86 0.0356 0.0044
ANAB / AnaptysBio, Inc. 0.00 -63.72 0.03 -76.12 0.0349 -0.0245
DYN / Dyne Therapeutics, Inc. 0.00 -79.38 0.03 -90.91 0.0341 -0.1209
MDWD / MediWound Ltd. 0.00 0.03 0.0329 0.0329
GBIO / Generation Bio Co. 0.05 0.00 0.03 -62.32 0.0280 -0.0025
KYTX / Kyverna Therapeutics, Inc. 0.01 0.00 0.03 -50.98 0.0270 0.0042
ALEC / Alector, Inc. 0.02 0.00 0.02 -38.46 0.0263 0.0090
CABA / Cabaletta Bio, Inc. 0.01 0.00 0.02 -53.85 0.0199 0.0024
DNA / Ginkgo Bioworks Holdings, Inc. 0.00 0.00 0.02 -5.26 0.0198 0.0111
ENTA / Enanta Pharmaceuticals, Inc. 0.00 -40.00 0.02 -63.27 0.0198 0.0012
CRGX / CARGO Therapeutics, Inc. 0.00 -81.15 0.02 -96.12 0.0181 -0.1751
PRLD / Prelude Therapeutics Incorporated 0.02 0.00 0.01 -27.78 0.0138 0.0059
CLYM / Climb Bio, Inc. 0.01 0.00 0.01 -56.00 0.0121 0.0009
WGSWW / GeneDx Holdings Corp. - Equity Warrant 0.01 0.00 0.00 100.00 0.0021 0.0016
RVMDW / Revolution Medicines, Inc. - Equity Warrant 0.01 0.00 0.00 -100.00 0.0006 -0.0004
US83444K1135 / SomaLogic Inc 0.00 0.00 0.00 0.0003 0.0002
US76105Y1091 / T. Rowe Price Government Reserve Fund 0.00 -99.96 0.00 -100.00 0.0001 -0.1208
BIOA / BioAge Labs, Inc. 0.00 -100.00 0.00 -100.00 -0.0432
BNTC / Benitec Biopharma Inc. 0.00 -100.00 0.00 -100.00 -0.0043
KRRO / Korro Bio, Inc. 0.00 -100.00 0.00 -100.00 -0.0206
SAGE / Sage Therapeutics, Inc. 0.00 -100.00 0.00 -100.00 -0.0219
NVO / Novo Nordisk A/S - Depositary Receipt (Common Stock) 0.00 -100.00 0.00 -100.00 -0.6752
SGMT / Sagimet Biosciences Inc. 0.00 -100.00 0.00 -100.00 -0.0306
TERN / Terns Pharmaceuticals, Inc. 0.00 -100.00 0.00 -100.00 -0.0238
BIOA / BioAge Labs, Inc. 0.00 -100.00 0.00 -100.00 -0.0432