Market Value1,538,677,000
Total Holdings194
File Date2013-11-14
Original Filing (Click here)

All hedge funds or institutions that manage over $100M are required by the SEC to file quarterly reports on their holdings. These reports are called 13F reports. However, the filings are required the following quarter from the reporting period, which means that by the time the filing is made (and we see them), the information could be five months old.

For funds with long term positions that make few trades, the holdings might closely resemble their current holdings, even after several months. However, for funds that have high turnover, the holdings data we see might differ significantly from their current holdings. Institutions are required to report CALL and PUT options, and those positions are identified in the table. However, they are not required to report short positions.

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Security Imputed
Share Price
Prev
Shares
Current
Shares
Change
(Percent)
Prev Value
(USD x1000)
Current Value
(USD x1000)
Change
(Percent)
AASTROM BIOSCIENCES INC / (00253U305)
ACAD / ACADIA Pharmaceuticals Inc.
ACAD / ACADIA Pharmaceuticals Inc. Call
ACAD / ACADIA Pharmaceuticals Inc. Put
ARAY / Accuray Incorporated
ARAY / Accuray Incorporated Call
ARAY / Accuray Incorporated Put
US00448Q2012 / Achillion Pharmaceuticals, Inc.
US00448Q2012 / Achillion Pharmaceuticals, Inc. Call
US00448Q2012 / Achillion Pharmaceuticals, Inc. Put
ACOR / Acorda Therapeutics, Inc. Call
AEGR / Aegerion Pharmaceuticals, Inc.
AEGR / Aegerion Pharmaceuticals, Inc. Call
AEGR / Aegerion Pharmaceuticals, Inc. Put
AGEN / Agenus Inc.
AGEN / Agenus Inc. Call
NWBO / Northwest Biotherapeutics, Inc.
US0153511094 / Alexion Pharmaceuticals, Inc. Call
ALXA / Alexza Pharmaceuticals, Inc. Call
018490100 / Allergan plc Call
018490100 / Allergan plc Put
AMRN / Amarin Corporation plc - Depositary Receipt (Common Stock)
AMRN / Amarin Corporation plc - Depositary Receipt (Common Stock) Call
AMRN / Amarin Corporation plc - Depositary Receipt (Common Stock) Put
CYTR / LadRx Corp Call
ANTH / Anthera Pharmaceuticals, Inc.
ARNA / Arena Pharmaceuticals Inc Call
ARNA / Arena Pharmaceuticals Inc Put
ARIA / ARIAD Pharmaceuticals, Inc.
ARIA / ARIAD Pharmaceuticals, Inc. Call
ARIA / ARIAD Pharmaceuticals, Inc. Put
ARROWHEAD RESEARCH CORP / Call (042797909)
ASTX / Investment Managers Series Trust II - Tradr 2X Long ASTS Daily ETF
ASTEX / American Funds Short-Term Tax-Exempt Bond Fund - American Funds Short-Term Tax-Exempt Bond Fund Class A Call
ASTEX / American Funds Short-Term Tax-Exempt Bond Fund - American Funds Short-Term Tax-Exempt Bond Fund Class A Put
AZN / AstraZeneca PLC - Depositary Receipt (Common Stock)
AZN / AstraZeneca PLC - Depositary Receipt (Common Stock) Call
AZN / AstraZeneca PLC - Depositary Receipt (Common Stock) Put
AVNR / Avanir Pharmaceuticals Inc
AVNR / Avanir Pharmaceuticals Inc Put
INCY / Incyte Corporation Call
BAX / Baxter International Inc. Call
TPST / Tempest Therapeutics, Inc.
BCRX / BioCryst Pharmaceuticals, Inc. Call
BMRN / BioMarin Pharmaceutical Inc. Call
BB / BlackBerry Limited Put
BMYMP / Bristol-Myers Squibb Company - Preferred Security Call
BMYMP / Bristol-Myers Squibb Company - Preferred Security Put
ACRX / Talphera, Inc. Call
CELG / Celgene Corp. Call
CELG / Celgene Corp. Put
CLDX / Celldex Therapeutics, Inc.
CLDX / Celldex Therapeutics, Inc. Call
CLDX / Celldex Therapeutics, Inc. Put
MLNT / Melinta Therapeutics, Inc.
CCXI / ChemoCentryx Inc Put
CLSN / Imunon Inc Call
CLSN / Imunon Inc Put
TENX / Tenax Therapeutics, Inc.
CNAT / Conatus Pharmaceuticals Inc.
CORONADO BIOSCIENCES INC / Put (21976U959)
CORONADO BIOSCIENCES INC / Call (21976U909)
OCUP / Opus Genetics, Inc.
CBST / Call
CBST / Put
CYBX / Cyberonics, Inc.
CYBX / Cyberonics, Inc. Put
DNDN /
DNDN / Put
DYAX / Dyax Corp.
EDAP / EDAP TMS S.A. - Depositary Receipt (Common Stock)
EW / Edwards Lifesciences Corporation Call
ELAN CORPORATION PLC / ADR Call (284131908)
LLY / Eli Lilly and Company
LLY / Eli Lilly and Company Put
ECYT / Endocyte, Inc. Call
ECYT / Endocyte, Inc. Put
ENTREMED INC / (29382F202)
EXAS / Exact Sciences Corporation Call
EXEL / Exelixis, Inc. Call
FCSC / Fibrocell Science Inc.
BIIB / Biogen Inc. Call
SLS / SELLAS Life Sciences Group, Inc. Put
ATHX / Athersys, Inc. Call
ATHX / Athersys, Inc. Put
GERN / Geron Corporation
GERN / Geron Corporation Call
GERN / Geron Corporation Put
GILD / Gilead Sciences, Inc.
GILD / Gilead Sciences, Inc. Call
GILD / Gilead Sciences, Inc. Put
GSK / GSK plc - Depositary Receipt (Common Stock) Call
GSK / GSK plc - Depositary Receipt (Common Stock) Put
HOLX / Hologic, Inc. Call
IMUC / EOM Pharmaceuticals Holdings, Inc. Put
INFI / Infinity Pharmaceuticals Inc. Call
INSM / Insmed Incorporated Put
INTERMUNE INC / Call (45884X903)
INTERMUNE INC / Put (45884X953)
IHRMF / iShares Public Limited Company - iShares MSCI Japan UCITS ETF USD (Dist)
ISHARES MSCI JAPAN ETF / ETF Put (464286958)
SPY / SPDR S&P 500 ETF Put
IONS / Ionis Pharmaceuticals, Inc.
ISR / Perspective Therapeutics Inc
IONS / Ionis Pharmaceuticals, Inc. Put
IONS / Ionis Pharmaceuticals, Inc. Call
HGEN / Humanigen, Inc.
KERX / Keryx Biopharmaceuticals, Inc.
KERX / Keryx Biopharmaceuticals, Inc. Call
KERX / Keryx Biopharmaceuticals, Inc. Put
MEIP / MEI Pharma, Inc. Call
MNKD / MannKind Corporation
MNKD / MannKind Corporation Call
MNKD / MannKind Corporation Put
MSTX / Tidal Trust II - Defiance Daily Target 2X Long MSTR ETF
MDCO / Medicines Company Call
MDVN / Medivation, Inc.
MDVN / Medivation, Inc. Call
MDVN / Medivation, Inc. Put
MRK / Merck & Co., Inc. Call
MRK / Merck & Co., Inc. Put
US60877T1007 / Momenta Pharmaceuticals, Inc. Call
NSPH / Nanosphere, Inc.
NKTR / Nektar Therapeutics Call
NKTR / Nektar Therapeutics Put
NBIX / Neurocrine Biosciences, Inc.
LUMO / Lumos Pharma, Inc. Call
NVAX / Novavax, Inc.
NUPATHE INC / Put (67059M950)
ACHV / Achieve Life Sciences, Inc.
ACHV / Achieve Life Sciences, Inc. Put
ONCY / Oncolytics Biotech Inc. Call
CASC / Cascadian Therapeutics, Inc.
ONTY / Oncothyreon, Inc. Call
ONXX / Onyx Pharmaceuticals Inc
ONYX / Onyx Acquisition Co. I Call
OPK / OPKO Health, Inc. Call
OPK / OPKO Health, Inc. Put
OREX / Orexigen Therapeutics, Inc. Call
OREX / Orexigen Therapeutics, Inc. Put
PBF / PBF Energy Inc. Call
PCYC / Pharmacyclics
PCYC / Pharmacyclics Call
PCYC / Pharmacyclics Put
PSTI / Pluristem Therapeutics Inc Put
REGN / Regeneron Pharmaceuticals, Inc. Call
REGN / Regeneron Pharmaceuticals, Inc. Put
76028H209 / Repros Therapeutics, Inc.
76028H209 / Repros Therapeutics, Inc. Call
76028H209 / Repros Therapeutics, Inc. Put
RIGL / Rigel Pharmaceuticals, Inc.
SLXP / Salix Therapeuticals, Inc.
SRPT / Sarepta Therapeutics, Inc.
SRPT / Sarepta Therapeutics, Inc. Call
SRPT / Sarepta Therapeutics, Inc. Put
SQNM / Sequenom, Inc.
SQNM / Sequenom, Inc. Call
SQNM / Sequenom, Inc. Put
TVIA / TerraVia Holdings, Inc.
TVIA / TerraVia Holdings, Inc. Put
SCON / Superconductor Technologies Inc.
GEVA / Synageva Biopharma Corp Call
MDGL / Madrigal Pharmaceuticals, Inc.
MDGL / Madrigal Pharmaceuticals, Inc. Put
MDGL / Madrigal Pharmaceuticals, Inc. Call
TEVA / Teva Pharmaceutical Industries Limited - Depositary Receipt (Common Stock)
TEVA / Teva Pharmaceutical Industries Limited - Depositary Receipt (Common Stock) Call
TEVA / Teva Pharmaceutical Industries Limited - Depositary Receipt (Common Stock) Put
TGTX / TG Therapeutics, Inc.
INVA / Innoviva, Inc. Call
TMP / Tompkins Financial Corporation
TRANSCEPT PHARMACEUTICALS INC / (89354M106)
TRANSCEPT PHARMACEUTICALS INC / Put (89354M956)
UNXLQ / Uni-Pixel, Inc. Call
UNXLQ / Uni-Pixel, Inc. Put
UTHR / United Therapeutics Corporation Call
VNDA / Vanda Pharmaceuticals Inc. Call
VNDA / Vanda Pharmaceuticals Inc. Put
VRTX / Vertex Pharmaceuticals Incorporated
VRTX / Vertex Pharmaceuticals Incorporated Call
VRTX / Vertex Pharmaceuticals Incorporated Put
BBI / Brickell Biotech Inc
/ VIVUS, Inc. Call
/ VIVUS, Inc. Put
WCG / Wellcare Health Plans, Inc. Call
XOMA / XOMA Royalty Corporation
XOMA / XOMA Royalty Corporation Put
ZIOP / Alaunos Therapeutics Inc Call
ZIOP / Alaunos Therapeutics Inc Put
ACRX / Talphera, Inc.
SEEL / Seelos Therapeutics, Inc. Put
OEF / iShares Trust - iShares S&P 100 ETF Call
OEF / iShares Trust - iShares S&P 100 ETF Put
OEF / iShares Trust - iShares S&P 100 ETF Put