Market Value1,783,644,000
Total Holdings232
File Date2014-05-14
Original Filing (Click here)

All hedge funds or institutions that manage over $100M are required by the SEC to file quarterly reports on their holdings. These reports are called 13F reports. However, the filings are required the following quarter from the reporting period, which means that by the time the filing is made (and we see them), the information could be five months old.

For funds with long term positions that make few trades, the holdings might closely resemble their current holdings, even after several months. However, for funds that have high turnover, the holdings data we see might differ significantly from their current holdings. Institutions are required to report CALL and PUT options, and those positions are identified in the table. However, they are not required to report short positions.

Click the link icon to see the full transaction history.

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Security Imputed
Share Price		 Prev
Shares		 Current
Shares		 Change
(Percent)		 Prev Value
(USD x1000)		 Current Value
(USD x1000)		 Change
(Percent)
ADXS / Ayala Pharmaceuticals, Inc. Put
ABBV / AbbVie Inc. Call
ABBV / AbbVie Inc. Put
ACAD / ACADIA Pharmaceuticals Inc.
ACAD / ACADIA Pharmaceuticals Inc. Call
ACAD / ACADIA Pharmaceuticals Inc. Put
US00448Q2012 / Achillion Pharmaceuticals, Inc. Call
US00448Q2012 / Achillion Pharmaceuticals, Inc. Put
ADXSW / Advaxis, Inc. Warrants
AEGR / Aegerion Pharmaceuticals, Inc.
AGEN / Agenus Inc.
AGEN / Agenus Inc. Call
AGEN / Agenus Inc. Put
IONS / Ionis Pharmaceuticals, Inc. Put
IONS / Ionis Pharmaceuticals, Inc. Call
ALXA / Alexza Pharmaceuticals, Inc. Call
ALIM / Alimera Sciences, Inc.
ALIM / Alimera Sciences, Inc. Put
018490100 / Allergan plc Call
018490100 / Allergan plc Put
AMRN / Amarin Corporation plc - Depositary Receipt (Common Stock)
AMRN / Amarin Corporation plc - Depositary Receipt (Common Stock) Call
AMGN / Amgen Inc.
AMGN / Amgen Inc. Put
AMPE / Ampio Pharmaceuticals, Inc.
AMPE / Ampio Pharmaceuticals, Inc. Put
ANTH / Anthera Pharmaceuticals, Inc.
ANTH / Anthera Pharmaceuticals, Inc. Call
BIIB / Biogen Inc. Call
BIIB / Biogen Inc. Put
ATHX / Athersys, Inc. Call
ATHX / Athersys, Inc. Put
AAPL / Apple Inc. Call
AAPL / Apple Inc. Put
ARNA / Arena Pharmaceuticals Inc
ARNA / Arena Pharmaceuticals Inc Put
ARIA / ARIAD Pharmaceuticals, Inc. Call
ARIA / ARIAD Pharmaceuticals, Inc. Put
ARROWHEAD RESEARCH CORP / Call (042797909)
ARROWHEAD RESEARCH CORP / Put (042797959)
BLRX / BioLineRx Ltd. - Depositary Receipt (Common Stock)
AUXL / Auxilium Pharmaceuticals Inc Call
AVNR / Avanir Pharmaceuticals Inc Call
AVNR / Avanir Pharmaceuticals Inc Put
BAX / Baxter International Inc. Call
BPTH / Bio-Path Holdings, Inc.
BDSI / Biodelivery Sciences International Put
BLUE / bluebird bio, Inc.
BMYMP / Bristol-Myers Squibb Company - Preferred Security Call
BMYMP / Bristol-Myers Squibb Company - Preferred Security Put
CVMW / CEL-SCI Corp. Warrants
PATI / Patriot Transportation Holding, Inc.
CELG / Celgene Corp.
CELG / Celgene Corp. Put
CLTX / Celsus Therapeutics
MLNT / Melinta Therapeutics, Inc.
CEMP / Cempra, Inc. Call
/ Ceres, Inc.
THMO / ThermoGenesis Holdings, Inc.
CLVS / Clovis Oncology Inc Call
CLVS / Clovis Oncology Inc Put
ACRX / Talphera, Inc. Call
ACRX / Talphera, Inc. Put
NWBO / Northwest Biotherapeutics, Inc. Call
CORT / Corcept Therapeutics Incorporated Call
CBST /
CBST / Put
CYTK / Cytokinetics, Incorporated Call
ASRT / Assertio Holdings, Inc. Call
DRNA / Dicerna Pharmaceuticals Inc
WINT / Windtree Therapeutics, Inc.
WINT / Windtree Therapeutics, Inc. Call
PSTI / Pluristem Therapeutics Inc Put
PSTI / Pluristem Therapeutics Inc
DYAX / Dyax Corp.
DYAX / Dyax Corp. Call
EDAP / EDAP TMS S.A. - Depositary Receipt (Common Stock)
EDAP / EDAP TMS S.A. - Depositary Receipt (Common Stock) Call
ENTA / Enanta Pharmaceuticals, Inc.
ENTA / Enanta Pharmaceuticals, Inc. Call
ECYT / Endocyte, Inc. Call
ECYT / Endocyte, Inc. Put
ENTREMED INC / (29382F202)
EPZM / Epizyme Inc
EXAS / Exact Sciences Corporation
EXAS / Exact Sciences Corporation Put
EXEL / Exelixis, Inc.
EXEL / Exelixis, Inc. Call
EXEL / Exelixis, Inc. Put
FURX / Furiex Pharmaceuticals, Inc.
FURX / Furiex Pharmaceuticals, Inc. Call
SLS / SELLAS Life Sciences Group, Inc.
SLS / SELLAS Life Sciences Group, Inc. Call
SLS / SELLAS Life Sciences Group, Inc. Put
ALBO / Albireo Pharma Inc Put
GILD / Gilead Sciences, Inc.
GILD / Gilead Sciences, Inc. Call
GILD / Gilead Sciences, Inc. Put
HZNP / Horizon Therapeutics Plc Put
451731103 / Ignyta, Inc.
IDIX / Idenix Pharmaceuticals Inc Call
IDRA / Idera Pharmaceuticals, Inc.
IDRA / Idera Pharmaceuticals, Inc. Call
IMUC / EOM Pharmaceuticals Holdings, Inc. Put
INCY / Incyte Corporation Call
INSM / Insmed Incorporated Call
INSM / Insmed Incorporated Put
INTERMUNE INC / Call (45884X903)
INTERMUNE INC / Put (45884X953)
IOC / InterOil Corporation
IOC / InterOil Corporation Put
HGEN / Humanigen, Inc.
KERX / Keryx Biopharmaceuticals, Inc.
KERX / Keryx Biopharmaceuticals, Inc. Put
LGNXZ / Ligand Pharmaceuticals Incorporated - Equity Right Call
SSKN / STRATA Skin Sciences, Inc.
MGNX / MacroGenics, Inc.
MNKD / MannKind Corporation Call
MNKD / MannKind Corporation Put
NWBO / Northwest Biotherapeutics, Inc. Put
MDGN.WS / Medgenics, Inc., Warrant
MDCO / Medicines Company Put
MDVN / Medivation, Inc. Call
MRK / Merck & Co., Inc. Call
MRK / Merck & Co., Inc. Put
US60877T1007 / Momenta Pharmaceuticals, Inc.
US60877T1007 / Momenta Pharmaceuticals, Inc. Call
US60877T1007 / Momenta Pharmaceuticals, Inc. Put
NKTR / Nektar Therapeutics
NKTR / Nektar Therapeutics Put
NEOSTEM INC / Put (640650954)
NBIX / Neurocrine Biosciences, Inc. Call
NBIX / Neurocrine Biosciences, Inc. Put
LUMO / Lumos Pharma, Inc. Call
LUMO / Lumos Pharma, Inc. Put
NVAX / Novavax, Inc.
NVAX / Novavax, Inc. Put
OCRX / Ocera Therapeutics, Inc.
OMER / Omeros Corporation
ACHV / Achieve Life Sciences, Inc. Call
ONTY / Oncothyreon, Inc. Call
ISEE / IVERIC bio Inc
ISEE / IVERIC bio Inc Put
OPK / OPKO Health, Inc.
OPK / OPKO Health, Inc. Call
OPK / OPKO Health, Inc. Put
OREX / Orexigen Therapeutics, Inc.
OREX / Orexigen Therapeutics, Inc. Put
ALTO / Alto Ingredients, Inc. Put
CDMO / Avid Bioservices, Inc.
PCYC / Pharmacyclics
PCYC / Pharmacyclics Call
PCYC / Pharmacyclics Put
PFE / Pfizer Inc. Call
PFE / Pfizer Inc. Put
PRAN / Prana Biotechnology Ltd.
PRNAF / Alterity Therapeutics Limited Call
PRNAF / Alterity Therapeutics Limited Put
PGNX / Progenics Pharmaceuticals, Inc.
PGNX / Progenics Pharmaceuticals, Inc. Call
PGNX / Progenics Pharmaceuticals, Inc. Put
PSDV / pSivida Corp. Call
PSDV / pSivida Corp. Put
PBYI / Puma Biotechnology, Inc. Call
PBYI / Puma Biotechnology, Inc. Put
REPH / Societal CDMO Inc
REGN / Regeneron Pharmaceuticals, Inc.
REGN / Regeneron Pharmaceuticals, Inc. Call
REGN / Regeneron Pharmaceuticals, Inc. Put
76028H209 / Repros Therapeutics, Inc. Put
RMTI / Rockwell Medical, Inc. Put
CBLI / Cytocom Inc
SPDR SERIES TRUST / TR Put (78464A950)
XBI / SPDR Series Trust - SPDR S&P Biotech ETF
SLXP / Salix Therapeuticals, Inc.
SLXP / Salix Therapeuticals, Inc. Put
SGMO / Sangamo Therapeutics, Inc.
SGMO / Sangamo Therapeutics, Inc. Call
SRPT / Sarepta Therapeutics, Inc.
SRPT / Sarepta Therapeutics, Inc. Call
SRPT / Sarepta Therapeutics, Inc. Put
SGEN / Seagen Inc Call
SGEN / Seagen Inc Put
SMLR / Semler Scientific, Inc.
ISR / Perspective Therapeutics Inc
VIRX / Viracta Therapeutics, Inc. Call
VIRX / Viracta Therapeutics, Inc. Put
GEVA / Synageva Biopharma Corp
GEVA / Synageva Biopharma Corp Call
GEVA / Synageva Biopharma Corp Put
SGYPQ / SYNERGY PHARMACEUTICALS INC DEL
ABUS / Arbutus Biopharma Corporation Call
TSRO / TESARO, Inc. Call
TSRO / TESARO, Inc.
TEVA / Teva Pharmaceutical Industries Limited - Depositary Receipt (Common Stock)
TEVA / Teva Pharmaceutical Industries Limited - Depositary Receipt (Common Stock) Call
TEVA / Teva Pharmaceutical Industries Limited - Depositary Receipt (Common Stock) Put
INVA / Innoviva, Inc.
INVA / Innoviva, Inc. Put
TMO / Thermo Fisher Scientific Inc.
TMO / Thermo Fisher Scientific Inc. Call
TNXP / Tonix Pharmaceuticals Holding Corp.
TROV / TrovaGene, Inc.
UTHR / United Therapeutics Corporation Call
UTHR / United Therapeutics Corporation Put
VRTX / Vertex Pharmaceuticals Incorporated Call
VRTX / Vertex Pharmaceuticals Incorporated Put
/ VIVUS, Inc.
/ VIVUS, Inc. Put
WCG / Wellcare Health Plans, Inc. Call
WCG / Wellcare Health Plans, Inc. Put
XOMA / XOMA Royalty Corporation
XOMA / XOMA Royalty Corporation Call
XOMA / XOMA Royalty Corporation Put
ZIOP / Alaunos Therapeutics Inc
ZIOP / Alaunos Therapeutics Inc Call
ZIOP / Alaunos Therapeutics Inc Put
ALKS / Alkermes plc
ALKS / Alkermes plc Call
ALKS / Alkermes plc Put
PRTA / Prothena Corporation plc Call
PRTA / Prothena Corporation plc Put
CGEN / Compugen Ltd. Call
GLMD / Galmed Pharmaceuticals Ltd.
QURE / uniQure N.V.
SEEL / Seelos Therapeutics, Inc.
CLSN / Imunon Inc Put
CLSN / Imunon Inc
SEEL / Seelos Therapeutics, Inc. Put
TENX / Tenax Therapeutics, Inc.
TENX / Tenax Therapeutics, Inc. Call
ACRX / Talphera, Inc.
ADMP / Adamis Pharmaceuticals Corp
CVM / CEL-SCI Corporation
AVEO / AVEO Pharmaceuticals Inc
TPST / Tempest Therapeutics, Inc.
LLY / Eli Lilly and Company Call
IWM / iShares Trust - iShares Russell 2000 ETF Put
SPY / SPDR S&P 500 ETF Put