Market Value1,840,121,000
Total Holdings256
File Date2017-05-15
Original Filing (Click here)

All hedge funds or institutions that manage over $100M are required by the SEC to file quarterly reports on their holdings. These reports are called 13F reports. However, the filings are required the following quarter from the reporting period, which means that by the time the filing is made (and we see them), the information could be five months old.

For funds with long term positions that make few trades, the holdings might closely resemble their current holdings, even after several months. However, for funds that have high turnover, the holdings data we see might differ significantly from their current holdings. Institutions are required to report CALL and PUT options, and those positions are identified in the table. However, they are not required to report short positions.

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Security Imputed
Share Price
Prev
Shares
Current
Shares
Change
(Percent)
Prev Value
(USD x1000)
Current Value
(USD x1000)
Change
(Percent)
BCLI / Brainstorm Cell Therapeutics Inc.
ANTH / Anthera Pharmaceuticals, Inc.
ADVM / Adverum Biotechnologies, Inc.
ONSIW / Oncobiologics, Inc. Series A Warrant Expiring 2/18/2018
STML / Stemline Therapeutics, Inc.
OPGN / OpGen, Inc.
CDTX / Cidara Therapeutics, Inc.
ZGNX / Zogenix Inc
NTLA / Intellia Therapeutics, Inc.
ZGNX / Zogenix Inc Call
SRPT / Sarepta Therapeutics, Inc. Call
US00163U1060 / AMAG Pharmaceuticals, Inc.
YMTX / Yumanity Therapeutics Inc
SLS / SELLAS Life Sciences Group, Inc. Call
CVM / CEL-SCI Corporation
MNKD / MannKind Corporation Put
DVAX / Dynavax Technologies Corporation Call
SYN / Synthetic Biologics Inc
PRTK / Paratek Pharmaceuticals Inc. Put
INCY / Incyte Corporation Put
ABBV / AbbVie Inc. Call
PARN / Parnell Pharmaceuticals Holdings Ltd.
BMY / Bristol-Myers Squibb Company
PBYI / Puma Biotechnology, Inc. Put
MTFB / Motif Bio plc ADRs
ABUS / Arbutus Biopharma Corporation Call
MRK / Merck & Co., Inc. Call
TSRO / TESARO, Inc. Put
98235T107 / Wright Medical Group N.V. Call
AMGN / Amgen Inc.
/ Immunomedics, Inc. Call
WINT / Windtree Therapeutics, Inc.
IMUC / EOM Pharmaceuticals Holdings, Inc.
CYTXW / Cytori Therapeutics, Inc. Warrants
BLRX / BioLineRx Ltd. - Depositary Receipt (Common Stock)
BLUE / bluebird bio, Inc. Put
OPK / OPKO Health, Inc. Put
SIOX / Sio Gene Therapies Inc. Put
INSM / Insmed Incorporated Call
SSKN / STRATA Skin Sciences, Inc.
TGTX / TG Therapeutics, Inc. Call
DRRX / DURECT Corporation
ACOR / Acorda Therapeutics, Inc. Call
FOLD / Amicus Therapeutics, Inc. Call
AEZS / COSCIENS Biopharma Inc. Put
CANF / Can-Fite BioPharma Ltd. - Depositary Receipt (Common Stock)
MBRX / Moleculin Biotech, Inc.
SGEN / Seagen Inc Put
GALT / Galectin Therapeutics Inc. Put
LUMO / Lumos Pharma, Inc. Call
MNKD / MannKind Corporation Call
ZGNX / Zogenix Inc Put
OTIC / Otonomy Inc Put
CRIS / Curis, Inc. Put
LRMR / Larimar Therapeutics, Inc. Call
LUMO / Lumos Pharma, Inc. Put
CAPR / Capricor Therapeutics, Inc.
BDSI / Biodelivery Sciences International
SAGE / Sage Therapeutics, Inc. Put
US0153511094 / Alexion Pharmaceuticals, Inc. Call
FOLD / Amicus Therapeutics, Inc. Put
ESPR / Esperion Therapeutics, Inc. Put
451731103 / Ignyta, Inc. Call
LXRX / Lexicon Pharmaceuticals, Inc. Put
EKSO / Ekso Bionics Holdings, Inc. Put
61166W101 / Monsanto Co. Call
CHEK / Check-Cap Ltd.
PTCT / PTC Therapeutics, Inc. Call
AMRN / Amarin Corporation plc - Depositary Receipt (Common Stock) Call
SIOX / Sio Gene Therapies Inc.
OREX / Orexigen Therapeutics, Inc. Put
SGLB / Sigma Labs Inc
BMRN / BioMarin Pharmaceutical Inc. Call
TXMD / TherapeuticsMD, Inc. Call
451731103 / Ignyta, Inc.
US0153511094 / Alexion Pharmaceuticals, Inc. Put
BIOA / BioAge Labs, Inc.
BLCM / Bellicum Pharmaceuticals, Inc.
SLNO / Soleno Therapeutics, Inc.
CYTX / Cytori Therapeutics, Inc.
SGMO / Sangamo Therapeutics, Inc. Put
IONS / Ionis Pharmaceuticals, Inc. Call
FGEN / FibroGen, Inc. Call
GENE / Genetic Technologies Limited - Depositary Receipt (Common Stock)
ALKS / Alkermes plc Call
PTCT / PTC Therapeutics, Inc. Put
SPDR S&P BIOTECH / Put (78464A950)
NUROW / NeuroMetrix, Inc. Warrants
OTIC / Otonomy Inc
74979C113 / RXI Pharmaceuticals Corporation, Warrants
SAGE / Sage Therapeutics, Inc.
GNMX / Aevi Genomic Medicine, Inc. Call
FLXN / Horizon Funds - Horizon Flexible Income ETF Put
TENX / Tenax Therapeutics, Inc.
GILD / Gilead Sciences, Inc. Call
VRTX / Vertex Pharmaceuticals Incorporated Put
CTSO / Cytosorbents Corporation
FOMX / Foamix Pharmaceuticals Ltd. Call
LJPC / La Jolla Pharmaceutical Co. Call
FWBI / First Wave BioPharma, Inc.
AZN / AstraZeneca PLC - Depositary Receipt (Common Stock) Put
BMYMP / Bristol-Myers Squibb Company - Preferred Security Put
ONSIZ / Oncobiologics, Inc. Series B Warrant Expiring 5/18
UTHR / United Therapeutics Corporation Call
VRTX / Vertex Pharmaceuticals Incorporated Call
CLVS / Clovis Oncology Inc Call
ACOR / Acorda Therapeutics, Inc.
RDHL / RedHill Biopharma Ltd. - Depositary Receipt (Common Stock)
HCA / HCA Healthcare, Inc. Call
FLXN / Horizon Funds - Horizon Flexible Income ETF Call
EIGR / Eiger BioPharmaceuticals, Inc.
ARDX / Ardelyx, Inc. Put
XENE / Xenon Pharmaceuticals Inc.
IPCI / Intellipharmaceutics International Inc.
MDGN / Medgenics, Inc.
US00448Q2012 / Achillion Pharmaceuticals, Inc. Call
ALNY / Alnylam Pharmaceuticals, Inc. Put
PRTA / Prothena Corporation plc Call
RNVAZ / Rennova Health, Inc. Warrants
STML / Stemline Therapeutics, Inc. Call
CI / The Cigna Group Call
AZN / AstraZeneca PLC - Depositary Receipt (Common Stock) Call
AMGN / Amgen Inc. Put
ARMP / Armata Pharmaceuticals, Inc.
VTGN / Vistagen Therapeutics, Inc.
BNTCW / Benitec Biopharma Ltd
PTCT / PTC Therapeutics, Inc.
INCY / Incyte Corporation Call
UTHR / United Therapeutics Corporation
SRRA / Sierra Oncology Inc
PSDV / pSivida Corp.
RIBT / RiceBran Technologies
FOMX / Foamix Pharmaceuticals Ltd.
ABUS / Arbutus Biopharma Corporation
H03579101 / Auris Medical Holding Ltd
GPL / Great Panther Mining Ltd Put
AVXS / AveXis, Inc. Call
SAGE / Sage Therapeutics, Inc. Call
BPMC / Blueprint Medicines Corporation
EDIT / Editas Medicine, Inc. Call
ABBV / AbbVie Inc. Put
MTFBW / Motif Bio plc Warrants
SIOX / Sio Gene Therapies Inc. Call
SLS / SELLAS Life Sciences Group, Inc.
/ Array BioPharma, Inc.
XLRN / Acceleron Pharma Inc Call
HES / Hess Corporation Call
DRRX / DURECT Corporation Call
OCGN / Ocugen, Inc.
OTLK / Outlook Therapeutics, Inc.
NURO / NeuroMetrix, Inc.
ALNY / Alnylam Pharmaceuticals, Inc. Call
ESPR / Esperion Therapeutics, Inc. Call
CHRS / Coherus Oncology, Inc.
ONCS / OncoSec Medical Inc
68232V116 / Onconova Therapeutics, Inc. Warrants
IONS / Ionis Pharmaceuticals, Inc.
RCKT / Rocket Pharmaceuticals, Inc.
JAZZ / Jazz Pharmaceuticals plc Call
LXRX / Lexicon Pharmaceuticals, Inc.
CYTK / Cytokinetics, Incorporated Call
ACOR / Acorda Therapeutics, Inc. Put
CMRX / Chimerix, Inc.
SPNC / Spectranetics Corp. (The) Put
SCMP / Sucampo Pharmaceuticals, Inc.
SPHS / Sophiris Bio Inc
MDCO / Medicines Company Call
CHRS / Coherus Oncology, Inc. Put
HALO / Halozyme Therapeutics, Inc. Call
CSBR / Champions Oncology, Inc.
CBMX / CombiMatrix Corp.
PTN / Palatin Technologies, Inc.
VTVT / vTv Therapeutics Inc.
US00163U1060 / AMAG Pharmaceuticals, Inc. Call
SGMO / Sangamo Therapeutics, Inc. Call
CRME / Cardiome Pharma Corp.
INSM / Insmed Incorporated Put
/ GW Pharmaceuticals Plc. Put
/ Array BioPharma, Inc. Put
APDN / Applied DNA Sciences, Inc.
ENLV / Enlivex Therapeutics Ltd.
MNKD / MannKind Corporation
45779A119 / InspireMD, Inc. Warrants
PALI / Palisade Bio, Inc.
NBSE / NeuBase Therapeutics, Inc.
RDUS / Radius Recycling, Inc.
DRWIW / Dragonwave, Inc.
APDNW / Applied DNA Sciences, Inc., Warrants
RARE / Ultragenyx Pharmaceutical Inc. Put
ONTX / Onconova Therapeutics, Inc.
DVAX / Dynavax Technologies Corporation Put
IONS / Ionis Pharmaceuticals, Inc. Put
NTLA / Intellia Therapeutics, Inc. Call
TGTX / TG Therapeutics, Inc. Put
VXZ / iPath Series B S&P 500 VIX Mid-Term Futures ETN - Corporate Bond/Note
IL0011177958 / Intec Pharma Ltd
SINT / Sintx Technologies, Inc.
STML / Stemline Therapeutics, Inc. Put
0PP / Portola Pharmaceuticals Inc Call
SPNC / Spectranetics Corp. (The)
GBT / Global Blood Therapeutics Inc. Call
LXRX / Lexicon Pharmaceuticals, Inc. Call
PBYI / Puma Biotechnology, Inc.
DRNA / Dicerna Pharmaceuticals Inc
EDIT / Editas Medicine, Inc.
RDUS / Radius Recycling, Inc. Put
IOVA / Iovance Biotherapeutics, Inc. Call
ALDX / Aldeyra Therapeutics, Inc.
BPTH / Bio-Path Holdings, Inc.
BLUE / bluebird bio, Inc. Call
SGLB / Sigma Labs Inc
IMUC.WS / ImmunoCellular Therapeutics, Ltd., Warrants
EDAP / EDAP TMS S.A. - Depositary Receipt (Common Stock) Put
PRTK / Paratek Pharmaceuticals Inc. Call
IOVA / Iovance Biotherapeutics, Inc.
BMYMP / Bristol-Myers Squibb Company - Preferred Security Call
ROKA / Roka Bioscience, Inc.
VCEL / Vericel Corporation
MRK / Merck & Co., Inc. Put
MRTX / Mirati Therapeutics, Inc.
SYBX / Synlogic, Inc.
XLB / The Select Sector SPDR Trust - The Materials Select Sector SPDR Fund Put
AMGN / Amgen Inc. Call
SGEN / Seagen Inc Call
EXEL / Exelixis, Inc. Call
TSRO / TESARO, Inc. Call
EXEL / Exelixis, Inc. Put
CASC / Cascadian Therapeutics, Inc.
FWP / Forward Pharma A/S - ADR
NSPR / InspireMD, Inc.
ADMS / Adamas Pharmaceuticals Inc Put
OASM / Oasmia Pharmaceutical AB
UTHR / United Therapeutics Corporation Put
ITCI / Intra-Cellular Therapies, Inc. Call
KITE / Kite Pharma, Inc. Put
PALI / Palisade Bio, Inc. Put
CYTR / LadRx Corp
LRMR / Larimar Therapeutics, Inc.
VIRX / Viracta Therapeutics, Inc.
/ GW Pharmaceuticals Plc. Call
AIM / AIM ImmunoTech Inc.
RNVA / Rennova Health, Inc.
0PP / Portola Pharmaceuticals Inc Put
NHWK / NightHawk Biosciences, Inc.
ARAV / Aravive, Inc. Call
ADXS / Ayala Pharmaceuticals, Inc. Call
OEF / iShares Trust - iShares S&P 100 ETF Call
SPY / SPDR S&P 500 ETF Put
SPY / SPDR S&P 500 ETF Call
OEF / iShares Trust - iShares S&P 100 ETF Put
ALQA / Alliqua, Inc.
VIRX / Viracta Therapeutics, Inc. Call
ADXS / Ayala Pharmaceuticals, Inc. Put
TPST / Tempest Therapeutics, Inc.
AVEO / AVEO Pharmaceuticals Inc
GEVO / Gevo, Inc.