Market Value1,528,563,000
Total Holdings216
File Date2017-09-27
Original Filing (Click here)

All hedge funds or institutions that manage over $100M are required by the SEC to file quarterly reports on their holdings. These reports are called 13F reports. However, the filings are required the following quarter from the reporting period, which means that by the time the filing is made (and we see them), the information could be five months old.

For funds with long term positions that make few trades, the holdings might closely resemble their current holdings, even after several months. However, for funds that have high turnover, the holdings data we see might differ significantly from their current holdings. Institutions are required to report CALL and PUT options, and those positions are identified in the table. However, they are not required to report short positions.

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Security Imputed
Share Price
Prev
Shares
Current
Shares
Change
(Percent)
Prev Value
(USD x1000)
Current Value
(USD x1000)
Change
(Percent)
GENE / Genetic Technologies Limited - Depositary Receipt (Common Stock)
ESPR / Esperion Therapeutics, Inc. Call
ESPR / Esperion Therapeutics, Inc. Put
CHEK / Check-Cap Ltd.
KPRX / Kiora Pharmaceuticals, Inc.
CRIS / Curis, Inc. Call
ADVM / Adverum Biotechnologies, Inc.
CYTR / LadRx Corp Put
TSRO / TESARO, Inc.
TSRO / TESARO, Inc. Call
TSRO / TESARO, Inc. Put
CRIS / Curis, Inc. Put
ADXS / Ayala Pharmaceuticals, Inc. Call
GWP / GW Pharmaceuticals plc
INSM / Insmed Incorporated Call
INSM / Insmed Incorporated Put
ATRS / Antares Pharma Inc Call
EXEL / Exelixis, Inc. Call
EXEL / Exelixis, Inc. Put
GNMX / Aevi Genomic Medicine, Inc. Call
YMTX / Yumanity Therapeutics Inc
AVXS / AveXis, Inc. Call
SAGE / Sage Therapeutics, Inc.
FOMX / Foamix Pharmaceuticals Ltd. Call
APDN / Applied DNA Sciences, Inc.
RCKT / Rocket Pharmaceuticals, Inc.
/ Array BioPharma, Inc.
IOVA / Iovance Biotherapeutics, Inc. Call
ROKA / Roka Bioscience, Inc.
BNTCW / Benitec Biopharma Ltd
SPDR S&P 500 ETF / TR Put (78464A950)
ABUS / Arbutus Biopharma Corporation Call
MRK / Merck & Co., Inc. Call
MRK / Merck & Co., Inc. Put
AEZS / COSCIENS Biopharma Inc.
AEZS / COSCIENS Biopharma Inc. Put
GALT / Galectin Therapeutics Inc. Put
UTHR / United Therapeutics Corporation Call
UTHR / United Therapeutics Corporation Put
DRNA / Dicerna Pharmaceuticals Inc
PRTK / Paratek Pharmaceuticals Inc. Call
PRTK / Paratek Pharmaceuticals Inc. Put
ADMP / Adamis Pharmaceuticals Corp Put
US0153511094 / Alexion Pharmaceuticals, Inc. Call
US0153511094 / Alexion Pharmaceuticals, Inc. Put
LUMO / Lumos Pharma, Inc.
LUMO / Lumos Pharma, Inc. Put
LUMO / Lumos Pharma, Inc. Call
CASC / Cascadian Therapeutics, Inc.
WVE / Wave Life Sciences Ltd.
IMUC / EOM Pharmaceuticals Holdings, Inc.
LRMR / Larimar Therapeutics, Inc. Call
XLRN / Acceleron Pharma Inc Call
SIOX / Sio Gene Therapies Inc.
PTN / Palatin Technologies, Inc.
CMRX / Chimerix, Inc.
ARDX / Ardelyx, Inc. Put
TGTX / TG Therapeutics, Inc. Put
SIOX / Sio Gene Therapies Inc. Call
SIOX / Sio Gene Therapies Inc. Put
HALO / Halozyme Therapeutics, Inc. Call
BMRN / BioMarin Pharmaceutical Inc. Call
ONCS / OncoSec Medical Inc
SGEN / Seagen Inc
SGEN / Seagen Inc Call
INCY / Incyte Corporation Call
INCY / Incyte Corporation Put
STML / Stemline Therapeutics, Inc. Call
STML / Stemline Therapeutics, Inc. Put
MTFB / Motif Bio plc ADRs
/ InspireMD Inc. Series B Warrants, exercisable for one share of common stock (Expiring March 14, 2022
US7616403090 / Rexahn Pharmaceuticals, Inc.
PCRX / Pacira BioSciences, Inc. Call
PCRX / Pacira BioSciences, Inc. Put
RNVA / Rennova Health, Inc.
APDNW / Applied DNA Sciences, Inc., Warrants
FOLD / Amicus Therapeutics, Inc. Put
MDCO / Medicines Company Call
MDCO / Medicines Company
MDCO / Medicines Company Put
ALNY / Alnylam Pharmaceuticals, Inc. Call
ALNY / Alnylam Pharmaceuticals, Inc. Put
CLVS / Clovis Oncology Inc
CAPR / Capricor Therapeutics, Inc.
CLVS / Clovis Oncology Inc Call
CYTR / LadRx Corp
SGLB / Sigma Labs Inc
ITCI / Intra-Cellular Therapies, Inc. Call
AZN / AstraZeneca PLC - Depositary Receipt (Common Stock) Call
AZN / AstraZeneca PLC - Depositary Receipt (Common Stock) Put
PBYI / Puma Biotechnology, Inc. Put
CLSN / Imunon Inc
FWBI / First Wave BioPharma, Inc.
61166W101 / Monsanto Co. Call
ABUS / Arbutus Biopharma Corporation
ONSIZ / Oncobiologics, Inc. Series B Warrant Expiring 5/18
74979C113 / RXI Pharmaceuticals Corporation, Warrants
US00163U1060 / AMAG Pharmaceuticals, Inc.
PARN / Parnell Pharmaceuticals Holdings Ltd.
US00163U1060 / AMAG Pharmaceuticals, Inc. Call
IMUC.WS / ImmunoCellular Therapeutics, Ltd., Warrants
RARE / Ultragenyx Pharmaceutical Inc. Put
DRWIW / Dragonwave, Inc.
TGTX / TG Therapeutics, Inc. Call
XENE / Xenon Pharmaceuticals Inc.
CDTX / Cidara Therapeutics, Inc.
FOLD / Amicus Therapeutics, Inc. Call
SPNC / Spectranetics Corp. (The)
MTFBW / Motif Bio plc Warrants
/ Immunomedics, Inc. Call
DBVT / DBV Technologies S.A. - Depositary Receipt (Common Stock)
CHRS / Coherus Oncology, Inc.
BPMC / Blueprint Medicines Corporation
SYN / Synthetic Biologics Inc
SYBX / Synlogic, Inc.
PBMD / Prima BioMed Ltd
CYTX / Cytori Therapeutics, Inc.
US00163U1060 / AMAG Pharmaceuticals, Inc. Put
98235T107 / Wright Medical Group N.V. Call
VXZ / iPath Series B S&P 500 VIX Mid-Term Futures ETN - Corporate Bond/Note
CRME / Cardiome Pharma Corp.
IL0011177958 / Intec Pharma Ltd
NSPR / InspireMD, Inc.
NTLA / Intellia Therapeutics, Inc. Call
KITE / Kite Pharma, Inc.
OREX / Orexigen Therapeutics, Inc.
PSDV / pSivida Corp.
BMYMP / Bristol-Myers Squibb Company - Preferred Security Call
ACOR / Acorda Therapeutics, Inc.
ACOR / Acorda Therapeutics, Inc. Call
ZGNX / Zogenix Inc Call
ZGNX / Zogenix Inc Put
ZGNX / Zogenix Inc
CBMX / CombiMatrix Corp.
WINT / Windtree Therapeutics, Inc.
ONSIW / Oncobiologics, Inc. Series A Warrant Expiring 2/18/2018
68232V116 / Onconova Therapeutics, Inc. Warrants
BMYMP / Bristol-Myers Squibb Company - Preferred Security Put
SPNC / Spectranetics Corp. (The) Put
45779A119 / InspireMD, Inc. Warrants
EIGR / Eiger BioPharmaceuticals, Inc.
PCRX / Pacira BioSciences, Inc.
IOVA / Iovance Biotherapeutics, Inc.
FWP / Forward Pharma A/S - ADR
SCMP / Sucampo Pharmaceuticals, Inc.
H03579101 / Auris Medical Holding Ltd
/ Array BioPharma, Inc. Put
LJPC / La Jolla Pharmaceutical Co. Call
RIBT / RiceBran Technologies
OREX / Orexigen Therapeutics, Inc. Put
VCEL / Vericel Corporation
STML / Stemline Therapeutics, Inc.
IOVA / Iovance Biotherapeutics, Inc. Put
/ Array BioPharma, Inc. Call
CTSO / Cytosorbents Corporation
OASM / Oasmia Pharmaceutical AB
JAZZ / Jazz Pharmaceuticals plc Call
MDGN / Medgenics, Inc.
UTHR / United Therapeutics Corporation
CSBR / Champions Oncology, Inc.
KITE / Kite Pharma, Inc. Put
SRRA / Sierra Oncology Inc
NUROW / NeuroMetrix, Inc. Warrants
CYTXW / Cytori Therapeutics, Inc. Warrants
NTLA / Intellia Therapeutics, Inc.
CHRS / Coherus Oncology, Inc. Put
FOMX / Foamix Pharmaceuticals Ltd.
ANTH / Anthera Pharmaceuticals, Inc.
BDSI / Biodelivery Sciences International
BMYMP / Bristol-Myers Squibb Company - Preferred Security
KDMN / Kadmon Holdings Inc
ADMS / Adamas Pharmaceuticals Inc Put
451731103 / Ignyta, Inc. Call
PALI / Palisade Bio, Inc. Put
451731103 / Ignyta, Inc.
MDGS / Medigus Ltd. - Depositary Receipt (Common Stock)
HES / Hess Corporation Call
RDUS / Radius Recycling, Inc.
RDUS / Radius Recycling, Inc. Put
XLB / The Select Sector SPDR Trust - The Materials Select Sector SPDR Fund Put
SGLB / Sigma Labs Inc
KTRA / Kintara Therapeutics, Inc.
EDIT / Editas Medicine, Inc.
EDIT / Editas Medicine, Inc. Call
ADXS / Ayala Pharmaceuticals, Inc.
/ GW Pharmaceuticals Plc. Put
/ GW Pharmaceuticals Plc. Call
FGEN / FibroGen, Inc. Call
PRTA / Prothena Corporation plc Call
OPGN / OpGen, Inc.
SRPT / Sarepta Therapeutics, Inc. Call
SRPT / Sarepta Therapeutics, Inc. Put
IPCI / Intellipharmaceutics International Inc.
AMGN / Amgen Inc.
AMGN / Amgen Inc. Call
AMGN / Amgen Inc. Put
IDXG / Interpace Biosciences, Inc.
ALDX / Aldeyra Therapeutics, Inc.
ALKS / Alkermes plc Call
ACOR / Acorda Therapeutics, Inc. Put
CI / The Cigna Group Call
SGEN / Seagen Inc Put
LRMR / Larimar Therapeutics, Inc.
EKSO / Ekso Bionics Holdings, Inc. Put
AMRN / Amarin Corporation plc - Depositary Receipt (Common Stock) Call
DRRX / DURECT Corporation
DRRX / DURECT Corporation Call
SPHS / Sophiris Bio Inc
OTLK / Outlook Therapeutics, Inc.
SINT / Sintx Technologies, Inc.
RNVAZ / Rennova Health, Inc. Warrants
PALI / Palisade Bio, Inc.
ENLV / Enlivex Therapeutics Ltd.
VRTX / Vertex Pharmaceuticals Incorporated Call
VRTX / Vertex Pharmaceuticals Incorporated Put
0PP / Portola Pharmaceuticals Inc Put
0PP / Portola Pharmaceuticals Inc Call
GPL / Great Panther Mining Ltd
GPL / Great Panther Mining Ltd Put
SLS / SELLAS Life Sciences Group, Inc.
ARMP / Armata Pharmaceuticals, Inc.
CYTK / Cytokinetics, Incorporated Call
IONS / Ionis Pharmaceuticals, Inc.
IONS / Ionis Pharmaceuticals, Inc. Call
ASXC / Asensus Surgical, Inc.
NHWK / NightHawk Biosciences, Inc.
MBRX / Moleculin Biotech, Inc.
BLCM / Bellicum Pharmaceuticals, Inc.
OTIC / Otonomy Inc
OTIC / Otonomy Inc Call
OTIC / Otonomy Inc Put
PBYI / Puma Biotechnology, Inc.
CERN / Cerner Corp. Call
GILD / Gilead Sciences, Inc. Call
HCA / HCA Healthcare, Inc. Call
IONS / Ionis Pharmaceuticals, Inc. Put
VKTX / Viking Therapeutics, Inc.
OCGN / Ocugen, Inc.
BIOA / BioAge Labs, Inc.
TXMD / TherapeuticsMD, Inc. Call
ATEC / Alphatec Holdings, Inc.
ABBV / AbbVie Inc. Call
ABBV / AbbVie Inc. Put
GBT / Global Blood Therapeutics Inc. Call
NURO / NeuroMetrix, Inc.
FLXN / Horizon Funds - Horizon Flexible Income ETF Call
FLXN / Horizon Funds - Horizon Flexible Income ETF Put
PTCT / PTC Therapeutics, Inc.
MRTX / Mirati Therapeutics, Inc.
OPK / OPKO Health, Inc. Put
ALQA / Alliqua, Inc.
LXRX / Lexicon Pharmaceuticals, Inc.
LXRX / Lexicon Pharmaceuticals, Inc. Call
LXRX / Lexicon Pharmaceuticals, Inc. Put
VTGN / Vistagen Therapeutics, Inc.
VTVT / vTv Therapeutics Inc.
US00448Q2012 / Achillion Pharmaceuticals, Inc. Call
BLUE / bluebird bio, Inc. Put
BLUE / bluebird bio, Inc. Call
BPTH / Bio-Path Holdings, Inc.
SLNO / Soleno Therapeutics, Inc.
NBSE / NeuBase Therapeutics, Inc.
SGMO / Sangamo Therapeutics, Inc. Call
SGMO / Sangamo Therapeutics, Inc. Put
CRMD / CorMedix Inc.
MNKD / MannKind Corporation
MNKD / MannKind Corporation Call
MNKD / MannKind Corporation Put
CRIS / Curis, Inc.
ATOS / Atossa Therapeutics, Inc.
SAGE / Sage Therapeutics, Inc. Put
SAGE / Sage Therapeutics, Inc. Call
PTCT / PTC Therapeutics, Inc. Call
PTCT / PTC Therapeutics, Inc. Put
VIRX / Viracta Therapeutics, Inc.
CANF / Can-Fite BioPharma Ltd. - Depositary Receipt (Common Stock)
VIRX / Viracta Therapeutics, Inc. Call
SLS / SELLAS Life Sciences Group, Inc. Call
SSKN / STRATA Skin Sciences, Inc.
EDAP / EDAP TMS S.A. - Depositary Receipt (Common Stock) Put
CVM / CEL-SCI Corporation
DVAX / Dynavax Technologies Corporation Put
DVAX / Dynavax Technologies Corporation Call
AIM / AIM ImmunoTech Inc.
TENX / Tenax Therapeutics, Inc.
MBOT / Microbot Medical Inc.
ARAV / Aravive, Inc. Call
SRNE / Sorrento Therapeutics, Inc.
RDHL / RedHill Biopharma Ltd. - Depositary Receipt (Common Stock)
AVEO / AVEO Pharmaceuticals Inc
BCLI / Brainstorm Cell Therapeutics Inc.
OEF / iShares Trust - iShares S&P 100 ETF Call
BLRX / BioLineRx Ltd. - Depositary Receipt (Common Stock)
ONTX / Onconova Therapeutics, Inc.
TPST / Tempest Therapeutics, Inc.
ADXS / Ayala Pharmaceuticals, Inc. Put
GEVO * / Gevo, Inc.
SPY / SPDR S&P 500 ETF Call
OEF / iShares Trust - iShares S&P 100 ETF Put
SPY / SPDR S&P 500 ETF Put