Market Value647,222,000
Total Holdings138
File Date2018-08-14
Original Filing (Click here)

All hedge funds or institutions that manage over $100M are required by the SEC to file quarterly reports on their holdings. These reports are called 13F reports. However, the filings are required the following quarter from the reporting period, which means that by the time the filing is made (and we see them), the information could be five months old.

For funds with long term positions that make few trades, the holdings might closely resemble their current holdings, even after several months. However, for funds that have high turnover, the holdings data we see might differ significantly from their current holdings. Institutions are required to report CALL and PUT options, and those positions are identified in the table. However, they are not required to report short positions.

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Security Imputed
Share Price		 Prev
Shares		 Current
Shares		 Change
(Percent)		 Prev Value
(USD x1000)		 Current Value
(USD x1000)		 Change
(Percent)
CHEK / Check-Cap Ltd.
BIIB / Biogen Inc. Call
BIIB / Biogen Inc.
BIIB / Biogen Inc. Put
ADVM / Adverum Biotechnologies, Inc.
ADVM / Adverum Biotechnologies, Inc. Call
TSRO / TESARO, Inc. Call
SESN / Sesen Bio Inc.
SESN / Sesen Bio Inc. Put
SGYPQ / SYNERGY PHARMACEUTICALS INC DEL Call
INSM / Insmed Incorporated
INSM / Insmed Incorporated Put
TBIO / Telesis Bio, Inc.
CYTXW / Cytori Therapeutics, Inc. Warrants
SCON / Superconductor Technologies Inc.
BMY / Bristol-Myers Squibb Company
CYTR / LadRx Corp
BBI / Brickell Biotech Inc
YTEN / Yield10 Bioscience, Inc.
INCY / Incyte Corporation Put
INCY / Incyte Corporation Call
MRK / Merck & Co., Inc. Call
MRK / Merck & Co., Inc. Put
THMO / ThermoGenesis Holdings, Inc.
NSPR / InspireMD, Inc.
NKTR / Nektar Therapeutics
NKTR / Nektar Therapeutics Put
MRK / Merck & Co., Inc.
ESPR / Esperion Therapeutics, Inc.
ESPR / Esperion Therapeutics, Inc. Call
XLRN / Acceleron Pharma Inc Put
XLRN / Acceleron Pharma Inc
XLRN / Acceleron Pharma Inc Call
SIOX / Sio Gene Therapies Inc.
ROSG / Rosetta Genomics, Ltd.
HALO / Halozyme Therapeutics, Inc.
HMNY / Helios and Matheson Analytics Inc.
HMNY / Helios and Matheson Analytics Inc. Call
HMNY / Helios and Matheson Analytics Inc. Put
FGEN / FibroGen, Inc. Call
AXSM / Axsome Therapeutics, Inc.
INCY / Incyte Corporation
/ InspireMD Inc. Series B Warrants, exercisable for one share of common stock (Expiring March 14, 2022
APDNW / Applied DNA Sciences, Inc., Warrants
FOLD / Amicus Therapeutics, Inc.
FOLD / Amicus Therapeutics, Inc. Put
ALNY / Alnylam Pharmaceuticals, Inc.
ONCE / Spark Therapeutics, Inc. Call
ALNY / Alnylam Pharmaceuticals, Inc. Put
IDXG / Interpace Biosciences, Inc.
ASXC / Asensus Surgical, Inc.
MRNS / Marinus Pharmaceuticals, Inc. Call
DBVT / DBV Technologies S.A. - Depositary Receipt (Common Stock) Call
APTX / Aptinyx Inc.
MGTA / Magenta Therapeutics Inc
XERS / Xeris Biopharma Holdings, Inc.
ODT / Odonate Therapeutics Inc
AZN / AstraZeneca PLC - Depositary Receipt (Common Stock)
AZN / AstraZeneca PLC - Depositary Receipt (Common Stock) Call
AZN / AstraZeneca PLC - Depositary Receipt (Common Stock) Put
ADOM / Envirotech Vehicles Inc
TROV / TrovaGene, Inc.
IMGN / ImmunoGen, Inc. Put
SLDB / Solid Biosciences Inc.
ONCE / Spark Therapeutics, Inc. Put
IMUC.WS / ImmunoCellular Therapeutics, Ltd., Warrants Call
US28249H1041 / Eidos Therapeutics, Inc.
AQB / AquaBounty Technologies, Inc.
OCLS / Oculus Innovative Sciences, Inc.
VKTX / Viking Therapeutics, Inc. Call
ZGNX / Zogenix Inc Call
ZGNX / Zogenix Inc Put
68232V116 / Onconova Therapeutics, Inc. Warrants
NONOF / Novo Nordisk A/S Call
NLTX / Neoleukin Therapeutics, Inc.
OPGN / OpGen, Inc.
EIGR / Eiger BioPharmaceuticals, Inc.
BNTCW / Benitec Biopharma Ltd
IMUC.WS / ImmunoCellular Therapeutics, Ltd., Warrants
PRPO / Precipio, Inc.
SLNO / Soleno Therapeutics, Inc.
BNTCW / Benitec Biopharma Ltd Call
VNRX / VolitionRx Limited
NONOF / Novo Nordisk A/S Put
SPDR S&P BIOTECH / TR Put (78464A950)
45779A119 / InspireMD, Inc. Warrants
H03579101 / Auris Medical Holding Ltd
FOLD / Amicus Therapeutics, Inc. Call
XENE / Xenon Pharmaceuticals Inc.
NVO / Novo Nordisk A/S - Depositary Receipt (Common Stock)
FGEN / FibroGen, Inc. Put
BMYMP / Bristol-Myers Squibb Company - Preferred Security Put
ABEO / Abeona Therapeutics Inc.
PRQR / ProQR Therapeutics N.V.
GLMD / Galmed Pharmaceuticals Ltd.
SGLB / Sigma Labs Inc
/ Achaogen Inc Put
VBLT / Vascular Biogenics Ltd
NLTX / Neoleukin Therapeutics, Inc. Put
FGEN / FibroGen, Inc.
PRTA / Prothena Corporation plc Call
PRTA / Prothena Corporation plc
PRTA / Prothena Corporation plc Put
SNES / SenesTech, Inc.
BIOA / BioAge Labs, Inc.
GALT / Galectin Therapeutics Inc. Put
GALT / Galectin Therapeutics Inc.
VRTX / Vertex Pharmaceuticals Incorporated Call
SRPT / Sarepta Therapeutics, Inc. Call
SRPT / Sarepta Therapeutics, Inc. Put
US0153511094 / Alexion Pharmaceuticals, Inc. Call
US0153511094 / Alexion Pharmaceuticals, Inc. Put
CYCC / Cyclacel Pharmaceuticals, Inc.
BIOC / Biocept Inc
ALKS / Alkermes plc Put
CHEK / Check-Cap Ltd.
CYTXW / Cytori Therapeutics, Inc. Warrants Call
PHIO / Phio Pharmaceuticals Corp.
AMRN / Amarin Corporation plc - Depositary Receipt (Common Stock)
AMRN / Amarin Corporation plc - Depositary Receipt (Common Stock) Call
AMRN / Amarin Corporation plc - Depositary Receipt (Common Stock) Put
DRRX / DURECT Corporation
DRRX / DURECT Corporation Call
BPTH / Bio-Path Holdings, Inc.
SPHS / Sophiris Bio Inc Call
SPHS / Sophiris Bio Inc Put
OTLK / Outlook Therapeutics, Inc.
EYEN / Eyenovia, Inc.
PHIO / Phio Pharmaceuticals Corp.
ZSAN / Zosano Pharma Corp
SLS / SELLAS Life Sciences Group, Inc. Call
SLS / SELLAS Life Sciences Group, Inc.
NKTR / Nektar Therapeutics Call
ASXC / Asensus Surgical, Inc. Put
ARMP / Armata Pharmaceuticals, Inc.
QNRX / Quoin Pharmaceuticals, Ltd. - Depositary Receipt (Common Stock)
ISEE / IVERIC bio Inc
ISEE / IVERIC bio Inc Call
ISEE / IVERIC bio Inc Put
/ Achaogen Inc Call
AKBA / Akebia Therapeutics, Inc.
RKDA / Arcadia Biosciences, Inc.
KZR / Kezar Life Sciences, Inc.
NAOV / NanoVibronix, Inc.
ZCOR / Zyla Life Sciences
EDAP / EDAP TMS S.A. - Depositary Receipt (Common Stock)
GLYC / GlycoMimetics, Inc.
FCEL / FuelCell Energy, Inc.
ATEC / Alphatec Holdings, Inc.
VTGN / Vistagen Therapeutics, Inc.
ABBV / AbbVie Inc. Call
AMRS / Amyris Inc Put
FCEL / FuelCell Energy, Inc. Put
GBT / Global Blood Therapeutics Inc. Call
XNTK / SPDR Series Trust - SPDR NYSE Technology ETF Call
INPX / Inpixon
NVIV / InVivo Therapeutics Holdings Corp.
CLSN / Imunon Inc
PAVM / PAVmed Inc.
PAVM / PAVmed Inc.
APDN / Applied DNA Sciences, Inc.
PSTI / Pluristem Therapeutics Inc
PSTI / Pluristem Therapeutics Inc Put
MBOT / Microbot Medical Inc.
CTXR / Citius Pharmaceuticals, Inc.
SGMO / Sangamo Therapeutics, Inc.
SGMO / Sangamo Therapeutics, Inc. Call
SGMO / Sangamo Therapeutics, Inc. Put
PULM / Pulmatrix, Inc.
CVM / CEL-SCI Corporation
MDGL / Madrigal Pharmaceuticals, Inc. Call
MNKD / MannKind Corporation
MNKD / MannKind Corporation Call
MNKD / MannKind Corporation Put
PTCT / PTC Therapeutics, Inc. Call
COGT / Cogent Biosciences, Inc.
GNPX / Genprex, Inc.
ALKS / Alkermes plc Call
VIRX / Viracta Therapeutics, Inc. Call
CANF / Can-Fite BioPharma Ltd. - Depositary Receipt (Common Stock)
VIRX / Viracta Therapeutics, Inc.
AYTU / Aytu BioPharma, Inc.
NUWE / Nuwellis, Inc.
TPST / Tempest Therapeutics, Inc.
SSKN / STRATA Skin Sciences, Inc.
EDAP / EDAP TMS S.A. - Depositary Receipt (Common Stock) Put
MDGS / Medigus Ltd. - Depositary Receipt (Common Stock)
AFMD / Affimed N.V. Call
AFMD / Affimed N.V.
AFMD / Affimed N.V. Put
AIM / AIM ImmunoTech Inc.
RSLS / ReShape Lifesciences Inc.
ARAV / Aravive, Inc. Call
ARAV / Aravive, Inc.
BCLI / Brainstorm Cell Therapeutics Inc.
ESPR / Esperion Therapeutics, Inc. Put
SEEL / Seelos Therapeutics, Inc.
NOVN / Novan Inc
ATNM / Actinium Pharmaceuticals, Inc.
NURO / NeuroMetrix, Inc.
ATOS / Atossa Therapeutics, Inc.
AVEO / AVEO Pharmaceuticals Inc Call
ONTX / Onconova Therapeutics, Inc.
SPY / SPDR S&P 500 ETF
SPY / SPDR S&P 500 ETF Put
OEF / iShares Trust - iShares S&P 100 ETF Call
OEF / iShares Trust - iShares S&P 100 ETF Put
SPY / SPDR S&P 500 ETF Call