Papan Peringkat Sentimen Analis

Terdapat banyak penelitian yang menunjukkan bahwa target harga analis dapat memprediksi target harga di masa mendatang. Misalnya, Asquith, Mikhail, dan Au (2005) berpendapat bahwa perkiraan target harga adalah salah satu sinyal yang paling informatif dengan nilai investasi yang besar. Halaman ini memberikan peringkat perusahaan dengan selisih terbesar antara harga saham perusahaan saat ini dan target analis konsensus.

Peringkat Keamanan Industri Kapitalisasi Pasar (Juta) Sasaran
Tinggi
Sasaran
Rendah
Sasaran
Rata-rata
Terbaru
Harga
Target Harga
% Perbedaan
Skor Sentimen Analis
18 LRMR / Larimar Therapeutics, Inc.
Larimar Therapeutics, Inc., based in the United States, operates within the biotechnology industry, focusing on the development of novel therapeutics for complex rare diseases. A key project of Larimar is their investigational therapy, CTI-1601, which is being developed as a potential treatment for Friedreich’s ataxia, a rare genetic neuromuscular disorder. This proprietary treatment involves a fusion protein designed to deliver human frataxin, the deficient protein in patients with Friedreich’s ataxia, which is essential for mitochondrial function. Larimar’s strategic approach combines rigorous scientific research with targeted clinical trials, aiming to address significant unmet medical needs in the rare disease space, thereby positioning itself as a pioneer in therapeutic innovation.
Mga Paghahanda sa Parmasyutiko 231.14 42.00 10.10 20.03 3.62 454.82 97.29
19 ALLO / Allogene Therapeutics, Inc. Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 248.75 14.70 2.52 7.80 1.13 587.49 97.09
23 VYGR / Voyager Therapeutics, Inc. Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 186.54 31.50 8.08 15.98 3.36 374.89 96.91
24 VKTX / Viking Therapeutics, Inc. Mga Paghahanda sa Parmasyutiko 6,077.04 131.25 29.29 92.40 27.05 241.40 96.90
28 NTLA / Intellia Therapeutics, Inc.
Intellia Therapeutics, Inc., based in the United States, operates primarily in the biotechnology industry, focusing on developing therapeutic products using CRISPR/Cas9 technology, a pioneering method in gene editing. The company is dedicated to creating in vivo treatments that amend defective genes from within the human body and ex vivo solutions for engineered cells targeting various illnesses. A significant project in Intellia's portfolio is its CRISPR/Cas9-based development programs targeting transthyretin amyloidosis, a rare, progressively debilitating disease. Through strategic collaborations and a robust development pipeline, Intellia Therapeutics, Inc. aims to leverage the transformative potential of genomics to produce therapeutic products that significantly improve patient outcomes in genetic diseases and oncology.
Mga In Vitro at In Vivo Diagnostic Substances 1,195.50 111.30 7.07 33.84 11.36 198.13 96.74
31 JANX / Janux Therapeutics, Inc. Mga Paghahanda sa Parmasyutiko 1,346.65 210.00 25.25 86.44 22.72 280.65 96.56
32 RARE / Ultragenyx Pharmaceutical Inc.
Ultragenyx Pharmaceutical Inc., headquartered in the United States, is a biopharmaceutical company primarily engaged in the research, development, and commercialization of novel products for the treatment of rare and ultra-rare genetic diseases. The company focuses on serious, debilitating genetic diseases that typically involve small, significantly underserved patient populations. Key projects include the development of therapies such as Crysvita for X-linked hypophosphatemia, Mepsevii for Mucopolysaccharidosis VII, and Dojolvi for long-chain fatty acid oxidation disorders. Ultragenyx aims to advance its pipeline by leveraging diverse technology platforms, including mRNA therapies, gene therapy, and cell therapy, proactively addressing some of the most complex rare diseases.
Mga Paghahanda sa Parmasyutiko 2,950.86 134.40 34.34 85.68 29.96 185.89 96.53
33 GPCR / Structure Therapeutics Inc. - Depositary Receipt (Common Stock) Mga Paghahanda sa Parmasyutiko 1,112.76 126.00 50.50 77.68 19.30 302.47 96.48
34 NRIX / Nurix Therapeutics, Inc. Mga Paghahanda sa Parmasyutiko 713.13 43.05 16.16 30.60 9.34 227.97 96.48
36 AUTL / Autolus Therapeutics plc - Depositary Receipt (Common Stock)
Autolus Therapeutics plc is a biopharmaceutical company based in the United Kingdom, primarily engaged in the development of cancer immunotherapies. The company specializes in the engineering of CAR-T (Chimeric Antigen Receptor T-cells) therapies that are designed to target and destroy cancer cells in a patient-specific approach. A key focus of Autolus Therapeutics’ research and development portfolio is on treatments for hematological cancers, including various forms of leukemia and lymphoma. Their innovative project, AUTO1, is a notable initiative aimed at improving the safety and efficacy of CAR-T therapies for adult acute lymphoblastic leukemia. Autolus is committed to advancing these therapies through clinical trials, aiming to leverage next-generation programmed T cell therapies for sustainable cancer treatments.
Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 397.88 13.65 5.05 9.65 1.50 545.43 96.36
40 BHVN / Biohaven Ltd. Mga Paghahanda sa Parmasyutiko 1,627.99 78.75 19.19 46.76 15.39 203.46 96.18
46 SYRE / Spyre Therapeutics, Inc.
Aeglea BioTherapeutics Inc. adalah perusahaan bioteknologi yang berbasis di AS yang berfokus pada pengembangan terapi berbasis enzim di bidang metabolisme asam amino.
Mga Paghahanda sa Parmasyutiko 994.95 74.55 21.21 55.42 16.49 236.29 96.09
47 STSFF / SmartStop Self Storage REIT, Inc. 46.20 38.38 41.00 9.90 96.05
48 ARCT / Arcturus Therapeutics Holdings Inc. Mga Paghahanda sa Parmasyutiko 461.79 147.00 25.25 62.93 17.01 269.98 95.98
49 CMPX / Compass Therapeutics, Inc. Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 481.22 33.60 7.07 13.46 3.49 286.90 95.83
50 BEAM / Beam Therapeutics Inc. Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 1,600.23 84.00 20.20 46.66 16.36 185.41 95.83
51 CABA / Cabaletta Bio, Inc. Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 132.61 23.10 2.02 11.79 1.45 715.69 95.81
55 EYPT / EyePoint Pharmaceuticals, Inc.
EyePoint Pharmaceuticals, Inc. is a biopharmaceutical company headquartered in the United States, primarily engaged in the development and commercialization of ophthalmic products for treating eye diseases. The company focuses on developing drug delivery systems that enhance the efficacy and duration of therapeutic effects. Key projects include DEXYCU, an FDA-approved intraocular product for postoperative inflammation, and YUTIQ, a treatment for chronic non-infectious uveitis affecting the posterior segment of the eye. EyePoint Pharmaceuticals employs a sustained-release technology to improve patient compliance and outcome. Their pipeline also demonstrates a commitment to addressing additional serious eye disorders, ensuring ongoing research and development in ocular disease treatment.
Mga Instrumentong Analitikal sa Laboratory 809.74 71.40 23.23 35.89 11.57 209.89 95.62
57 KURA / Kura Oncology, Inc.
Kura Oncology, Inc., based in the United States, is a clinical-stage biopharmaceutical company focused primarily on the research and development of medications targeted at the treatment of cancer. The company's pipeline is centered around small molecule therapeutics that modulate oncogenic drivers in cancer cells, aiming to address the underlying causes of the disease and improve patient outcomes. Among its key projects is tipifarnib, a farnesyl transferase inhibitor designed primarily for the treatment of patients with HRAS mutant head and neck cancer, showcasing the company's commitment to targeting genetically defined cancers through molecularly targeted therapies. Kura Oncology's strategic initiatives emphasize the development and commercialization of these innovative oncology therapies, demonstrating a clear path towards addressing unmet medical needs in the oncology sector.
Mga Paghahanda sa Parmasyutiko 685.70 42.00 8.08 25.93 7.90 228.58 95.60
59 ENGN / enGene Holdings Inc. 236.46 31.50 7.07 21.98 4.62 374.65 95.56
62 VERA / Vera Therapeutics, Inc. Mga Paghahanda sa Parmasyutiko 1,380.51 105.00 23.23 66.86 21.64 209.09 95.45
63 MRSN / Mersana Therapeutics, Inc.
Mersana Therapeutics, Inc., based in the United States, operates within the biotechnology sector, focusing on innovating antibody-drug conjugates (ADCs) for cancer treatment. The company leverages its proprietary platforms, Dolasynthen and Immunosynthen, to develop therapies that aim to significantly improve patient outcomes by targeting tumor cells while minimizing the impact on healthy cells. Key projects include developmental therapies such as XMT-1536 and XMT-1592, targeting ailments like non-small cell lung cancer and ovarian cancer. Mersana’s strategy emphasizes collaborations and partnerships to advance its clinical trials, ensuring a robust pipeline of therapeutic candidates positioned for both clinical success and potential market entry.
Mga Paghahanda sa Parmasyutiko 36.53 341.25 8.08 94.57 7.32 1,190.16 95.44
64 CRBP / Corbus Pharmaceuticals Holdings, Inc.
Corbus Pharmaceuticals Holdings adalah perusahaan tahap klinis yang berfokus pada pengembangan dan komersialisasi obat-obatan baru yang dirancang untuk menargetkan sistem endocannabinoid.
Mga Paghahanda sa Parmasyutiko 114.94 57.75 28.28 41.48 9.37 342.22 95.43
65 SLDB / Solid Biosciences Inc. Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 425.26 21.00 10.10 16.13 5.48 194.70 95.41
66 RLAY / Relay Therapeutics, Inc. Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 614.66 19.95 4.04 13.57 3.59 278.94 95.40
67 MREO / Mereo BioPharma Group plc - Depositary Receipt (Common Stock)
Mereo BioPharma Group plc, based in the United Kingdom, operates within the biopharmaceutical sector, focusing primarily on developing and commercializing innovative therapies for rare diseases. The company has a portfolio concentrating on endocrinology, oncology, and rare genetic diseases. One of their key projects includes BPS-804 (setrusumab), a treatment designed for osteogenesis imperfecta, a rare bone disorder. Mereo BioPharma also works on advancing treatments like acumapimod, aimed at addressing acute exacerbations of chronic obstructive pulmonary disease (AECOPD), and alvelestat for alpha-1 antitrypsin deficiency, a genetic disorder that affects the lungs and liver. Their strategic approach combines in-licensing and acquiring under-prioritized programs from larger pharmaceutical companies to manage and propel these products through advanced clinical development stages.
Mga Paghahanda sa Parmasyutiko 271.10 9.45 5.05 7.27 1.71 326.25 95.35
68 CGEM / Cullinan Therapeutics, Inc. Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 445.72 35.70 22.22 27.88 7.54 269.52 95.30
70 PCVX / Vaxcyte, Inc. Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 3,994.45 171.15 50.50 117.17 30.79 280.80 95.14
71 IMVT / Immunovant, Inc. Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 2,513.01 59.85 16.16 40.46 14.69 175.52 95.13
72 RGNX / REGENXBIO Inc.
REGENXBIO Inc. is a biotechnology company based in the United States, notably situated within the competitive biopharmaceutical sector. The company is primarily focused on the development, commercialization, and licensing of its proprietary NAV Technology Platform, which it uses to create gene therapies that address genetic defects or enable cells in the body to produce therapeutic proteins that are missing or deficient. One of its key projects includes gene therapies for the treatment of wet age-related macular degeneration, a leading cause of blindness. A hallmark of REGENXBIO's approach lies in its extensive collaborative efforts, including partnerships with leading pharmaceutical entities to expand the reach and application of its gene therapy innovations.
Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 450.23 54.60 14.14 31.03 8.93 247.23 95.10
77 LEGN / Legend Biotech Corporation - Depositary Receipt (Common Stock)
Legend Biotech Corporation is a biopharmaceutical company based in Somerset, New Jersey, with a primary focus on the development and commercialization of novel cell therapies for oncology and other indications. As a leader in the biotechnology industry, the company leverages innovative technologies to develop treatments that address unmet medical needs, particularly in the realm of cancer. One of its key projects includes the development of CAR-T therapies, notably their BCMA-targeted CAR-T cell therapy, which has shown promise in treating multiple myeloma, a type of blood cancer. Legend Biotech's commitment to groundbreaking research and therapeutic development places it at the forefront of cellular therapy advancements, striving to enhance patient outcomes in areas with significant therapeutic gaps.
Mga Paghahanda sa Parmasyutiko 6,410.14 98.70 53.65 76.34 34.73 119.82 94.95
79 DNLI / Denali Therapeutics Inc.
Denali Therapeutics Inc., based in the United States, operates primarily within the biotechnology industry, focusing on the discovery and development of therapies for patients with neurodegenerative diseases such as Alzheimer's, Parkinson's, ALS, and others. The company leverages its proprietary technology platforms to create a pipeline of potential therapeutics aimed at treating these complex diseases. Key projects include their RIPK1 inhibitor program, aimed at tackling neuroinflammation, and their LRRK2 inhibitor program, addressing genetic mutations associated with Parkinson’s disease. Denali’s approach emphasizes rigorous biomarker and genetic validation to advance their projects from preclinical stages toward clinical trials, aiming to meet significant unmet medical needs in neurodegenerative conditions.
Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 2,224.62 42.00 25.25 32.79 15.27 114.55 94.93
82 CRNX / Crinetics Pharmaceuticals, Inc.
Crinetics Pharmaceuticals, Inc., based in the United States, is a biopharmaceutical company primarily engaged in the discovery, development, and commercialization of novel therapeutics targeting endocrine-related diseases and endocrine-related tumors. The company focuses on developing treatments that address unmet medical needs in diseases such as acromegaly and Cushing's disease. Key projects include paltusotine (CRN00808), currently in advanced clinical trials for acromegaly, and other early-stage candidates targeting various endocrine disorders. Crinetics combines strategic research and development initiatives with cutting-edge medical science to provide innovative hormone-targeting therapies designed to improve the lives of patients worldwide by tackling complex endocrine system dysfunctions.
Mga Paghahanda sa Parmasyutiko 2,916.96 101.85 35.35 71.88 30.99 131.97 94.90
83 XNCR / Xencor, Inc. Mga Paghahanda sa Parmasyutiko 579.29 42.00 6.06 26.29 8.13 223.61 94.85
84 KRRO / Korro Bio, Inc. Mga Paghahanda sa Parmasyutiko 215.90 189.00 25.25 94.18 23.08 309.66 94.83
86 CLDX / Celldex Therapeutics, Inc.
Celldex Therapeutics, Inc., based in the United States, operates primarily in the biopharmaceutical sector, focusing on the development and commercialization of innovative therapies for debilitating diseases. The company is a leader in the field of cancer immunotherapy, investing heavily in research and development to pioneer novel drug candidates designed to exploit the power of the immune system to combat cancer and other serious diseases. Key projects include varied clinical trials targeting hard-to-treat conditions, such as glioblastoma and triple-negative breast cancer, leveraging proprietary technologies like antibody-based therapeutics. Through these endeavors, Celldex continues to advance its mission of achieving breakthroughs in patient care and enhancing treatment outcomes.
Mga In Vitro at In Vivo Diagnostic Substances 1,466.11 94.50 30.30 56.73 22.08 157.15 94.78
87 CATX / Perspective Therapeutics, Inc.
Perspective Therapeutics, Inc., based in the United States, operates within the biotechnology sector with a primary focus on the development of targeted radiotherapeutics for cancer treatment. At the core of its portfolio is a series of projects aimed at advancing the use of radiolabeled small molecules and antibodies that selectively target and destroy cancer cells while minimizing exposure to healthy tissues. The company emphasizes innovation in the radioisotope drug conjugate space, specifically developing therapies that employ isotopes like Actinium-225 and Lutetium-177. These efforts are driven by the aim to improve treatment outcomes and extend survival rates for patients battling various malignancies, marking Perspective Therapeutics as a key player in the oncological radiotherapy industry.
Mga Paghahanda sa Parmasyutiko 249.52 21.00 5.05 13.73 3.36 309.87 94.78
88 DYN / Dyne Therapeutics, Inc. Serbisyong Elektrisidad 1,542.43 52.50 11.62 36.55 13.49 170.84 94.76
89 BCYC / Bicycle Therapeutics plc - Depositary Receipt (Common Stock)
Bicycle Therapeutics plc, headquartered in Cambridge, UK, operates primarily in the biotechnology industry and focuses on developing transformative medicines through its proprietary bicyclic peptide (Bicycle®) technology. This innovative technology platform enables the creation of new classes of therapeutics which possess the affinity and specificity typical of antibodies, coupled with the tissue penetration ability of small molecules, aimed at treating cancer and other debilitating diseases. Key projects include their lead candidates BT1718, a novel Bicycle Toxin Conjugate targeted at tumors expressing Membrane Type 1 Matrix Metalloproteinase, and BT5528, a second-generation Bicycle Toxin Conjugate aimed at the EphA2 receptor, a target associated with poor prognosis cancers. Their approach to drug development pioneers avenues in oncology, specifically using a tumor-targeted immune cell agonists strategy to activate immune responses against cancers.
Mga Paghahanda sa Parmasyutiko 512.48 46.20 10.10 24.91 7.38 236.55 94.71
90 TSHA / Taysha Gene Therapies, Inc. Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 796.37 14.70 5.05 8.84 2.92 202.74 94.70
91 ATYR / aTyr Pharma, Inc.
aTyr Pharma, Inc. is an American biotechnology company based in San Diego, California, specializing in the discovery and development of innovative medicines based on novel biological pathways. Its primary focus is on therapeutics that harness the potential of tRNA synthetases. One of the key projects is centered around ATYR1923 (efzofitimod), a fusion protein in clinical development for the treatment of various severe inflammatory lung diseases, including pulmonary sarcoidosis and interstitial lung disease. aTyr Pharma leverages its proprietary knowledge of tRNA synthetase biology to target underserved patient populations with grievous diseases, positioning itself strategically within the biotech industry to address significant unmet medical needs.
Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 498.25 36.75 9.09 19.74 5.38 267.88 94.63
92 ATXS / Astria Therapeutics, Inc. Mga Paghahanda sa Parmasyutiko 348.48 49.35 16.16 30.22 6.18 389.35 94.55
93 ETNB / 89bio, Inc. Mga Paghahanda sa Parmasyutiko 1,425.66 57.75 11.11 29.86 9.03 230.84 94.53
94 APGE / Apogee Therapeutics, Inc. Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 2,126.33 121.80 78.78 98.68 36.37 171.78 94.51
96 DNTH / Dianthus Therapeutics, Inc.
Dianthus Therapeutics, Inc., based in the United States, operates within the biotechnology industry, focusing primarily on developing innovative therapeutic solutions. The company is dedicated to advancing the field of immunology, with a significant emphasis on designing and commercializing novel treatments meant to address autoimmune and inflammatory diseases. Key projects include the development of targeted therapies that aim to modulate the immune system in a precise manner, thereby offering potential benefits over traditional treatments with fewer side effects and improved efficacy. Dianthus Therapeutics leverages cutting-edge research and technology to build a robust pipeline of drug candidates, positioning it as a formidable player in the medical research arena focused on transformative healthcare solutions.
Mga Paghahanda sa Parmasyutiko 756.47 96.60 34.34 53.24 23.57 126.47 94.42
99 PRQR / ProQR Therapeutics N.V.
ProQR Therapeutics N.V. is a biopharmaceutical company based in the Netherlands, primarily focused on developing transformative RNA therapies for severe genetic rare diseases. ProQR leverages its proprietary technology platforms to enhance RNA molecules for specific therapeutic targeting. A notable project includes their lead compound, sepofarsen, designed for the treatment of Leber’s congenital amaurosis, an inherited form of blindness. Additionally, the company is advancing a broad pipeline that includes potential treatments for cystic fibrosis and dystrophic epidermolysis bullosa. ProQR’s strategic approach combines rigorous scientific research with a commitment to addressing unmet medical needs in the area of genetic disorders, aiming to offer innovative solutions that significantly improve patient care.
Mga Paghahanda sa Parmasyutiko 236.50 14.70 4.04 9.18 2.25 308.91 94.30
100 ORKA / Oruka Therapeutics, Inc. 553.90 49.35 15.15 40.29 14.80 172.41 94.28
101 ALMS / Alumis Inc. 482.24 26.25 14.14 19.38 4.64 318.12 94.24
102 SNDX / Syndax Pharmaceuticals, Inc.
Syndax Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company based in the United States, primarily engaged in the development of cancer therapies. The company focuses on pioneering treatments that can potentially control the expression of genes implicated in cancer progression. Among its key projects, Syndax is developing entinostat, an oral small molecule that targets immune regulatory cells and cancer cells' growth and survival. Additionally, their pipeline includes SNDX-5613, part of a novel class of selective inhibitors against acute leukemia. Syndax Pharmaceuticals emphasizes combination strategies to enhance the effectiveness of current cancer treatments, thereby aiming to address the unmet medical needs in multiple cancer types.
Mga Paghahanda sa Parmasyutiko 1,405.34 58.80 19.19 38.11 16.33 133.38 94.20
104 TRVI / Trevi Therapeutics, Inc. Mga Paghahanda sa Parmasyutiko 883.48 28.35 13.13 21.01 7.26 189.62 94.15
105 VRDN / Viridian Therapeutics, Inc. Mga Paghahanda sa Parmasyutiko 1,501.57 64.05 19.19 39.72 18.38 115.97 94.09
108 CYTK / Cytokinetics, Incorporated
Cytokinetics, Incorporated, based in the United States, operates within the biopharmaceutical sector, focusing primarily on the discovery, development, and commercialization of muscle activators as potential treatments for people with debilitating diseases in which muscle performance is compromised and/or declining. As a leader in muscle biology research, the company has leveraged its expertise to advance a pipeline of drug candidates such as omecamtiv mecarbil for heart failure, and reldesemtiv for conditions linked to skeletal muscle weaknesses, like ALS and SMA. The firm's strategic approach combines targeted biological understanding with rigorous clinical testing to address unmet medical needs, underlining its commitment to enhancing health outcomes and quality of life for patients with severe muscular diseases.
Mga Paghahanda sa Parmasyutiko 4,224.40 126.00 41.41 73.38 35.33 107.77 93.95
109 ACRV / Acrivon Therapeutics, Inc. Mga Paghahanda sa Parmasyutiko 42.14 19.95 6.06 11.39 1.34 750.00 93.91
110 LXEO / Lexeo Therapeutics, Inc. Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 258.92 29.40 9.09 17.78 4.79 270.74 93.89
112 TNYA / Tenaya Therapeutics, Inc. Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 184.16 9.45 3.03 5.27 1.13 366.37 93.83
113 OLMA / Olema Pharmaceuticals, Inc. Mga Paghahanda sa Parmasyutiko 374.71 31.50 18.18 24.82 5.46 355.41 93.82
114 RCUS / Arcus Biosciences, Inc. Mga Paghahanda sa Parmasyutiko 1,126.78 54.60 12.12 29.77 10.59 180.81 93.77
115 EWTX / Edgewise Therapeutics, Inc. Mga Paghahanda sa Parmasyutiko 1,511.65 53.55 14.14 38.95 14.35 171.40 93.71
116 QURE / uniQure N.V. Mga Paghahanda sa Parmasyutiko 897.60 73.50 13.13 36.63 16.33 123.88 93.68
117 TRML / Tourmaline Bio, Inc. Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 601.58 73.50 35.35 57.32 23.40 144.82 93.56
121 CAPR / Capricor Therapeutics, Inc.
Capricor Therapeutics, Inc., headquartered in the United States, operates primarily in the biotechnology sector. It focuses on the development of biological therapies for diseases with unmet medical needs, including rare disorders such as Duchenne muscular dystrophy (DMD) and other conditions involving cardiac and skeletal muscle deterioration. A key project involves its lead candidate, CAP-1002, which consists of allogeneic cardiosphere-derived cells aimed at modulating the body's immune response and facilitating muscle regeneration. The company's innovative approach highlights its dedication to addressing pivotal health challenges by harnessing the therapeutic potential of cell and exosome technology, which has placed it at the forefront of regenerative medicine and treatment of muscle-related diseases.
Mga Paghahanda sa Parmasyutiko 287.53 30.45 12.12 21.01 6.28 234.05 93.53
122 HOWL / Werewolf Therapeutics, Inc. Mga Paghahanda sa Parmasyutiko 59.39 12.60 3.03 7.48 1.31 466.66 93.52
123 UNCY / Unicycive Therapeutics, Inc. Mga Paghahanda sa Parmasyutiko 58.56 110.25 30.30 64.39 4.19 1,451.51 93.48
124 ANNX / Annexon, Inc. Mga Paghahanda sa Parmasyutiko 225.71 14.70 9.09 11.83 2.06 475.77 93.44
127 FDMT / 4D Molecular Therapeutics, Inc. Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 287.44 42.00 10.10 29.35 6.16 376.90 93.40
128 TVTX / Travere Therapeutics, Inc. Mga Paghahanda sa Parmasyutiko 1,558.40 49.35 20.20 34.76 17.50 98.73 93.35
130 OABI / OmniAb, Inc. Komersyal na Pisikal at Biyolohikal na Pananaliksik 196.32 11.55 3.03 8.01 1.60 400.89 93.32
131 ANAB / AnaptysBio, Inc.
AnaptysBio, Inc., based in the United States, operates within the biotechnology industry, focusing on the development of novel immuno-oncology therapeutics. This company is engaged in pioneering antibody-based approaches for the treatment of significant unmet medical needs in inflammation and immune-oncology. AnaptysBio has been instrumental in advancing various proprietary programs, including ANB030, which targets PD-1, and ANB032, aimed at BTLA, both of which are designed to modulate immune responses central to many diseases. Through strategic partnerships and a robust in-house pipeline, AnaptysBio strives to advance the development of therapeutic antibodies, potentially transforming treatment paradigms in autoimmunity and cancer.
Mga Paghahanda sa Parmasyutiko 568.69 94.50 20.20 47.53 20.33 133.69 93.32
136 TCRX / TScan Therapeutics, Inc. Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 102.71 12.60 3.03 8.67 1.80 379.01 93.23
137 WVE / Wave Life Sciences Ltd. Mga Paghahanda sa Parmasyutiko 1,494.46 37.80 9.09 20.54 9.60 113.92 93.20
139 IMCR / Immunocore Holdings plc - Depositary Receipt (Common Stock)
Immunocore Holdings plc, based in the United Kingdom, operates in the biotechnology sector, focusing primarily on the development of novel T cell receptor (TCR) based immunotherapies. The company's flagship technology, ImmTAX (Immune mobilizing monoclonal TCRs Against X disease), is designed to exploit the power of the body’s own immune system to treat a range of diseases, including cancer, infectious, and autoimmune diseases. A key project includes tebentafusp (IMCgp100), which targets melanoma and has shown promise in clinical trials. Armed with cutting-edge technology and an innovative approach, Immunocore aims to transform the treatment landscape for patients with hard-to-treat diseases, positioning itself as a leader in TCR immunotherapy.
Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 1,621.48 105.00 24.24 63.99 32.22 98.78 93.18
140 CRBU / Caribou Biosciences, Inc. Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 173.67 33.60 1.01 9.03 1.87 384.41 93.18
142 MXCT / MaxCyte, Inc.
MaxCyte, Inc., headquartered in Gaithersburg, Maryland, USA, operates primarily in the biotechnology sector, where it focuses on cell engineering through its proprietary flow electroporation technology. This cutting-edge technology facilitates the development and commercialization of cell-based therapies and life science research applications. MaxCyte's notable projects include strategic collaborations with leading pharmaceutical and biotechnology companies to enhance the discovery, development, and manufacture of new therapeutics, particularly in the burgeoning field of cell therapy. The company supports advancements in drug development and cellular research by providing high-performance cell engineering solutions that are both scalable and capable of high-volume processing, thereby addressing critical needs within the biotech industry.
Komersyal na Pisikal at Biyolohikal na Pananaliksik 148.70 9.45 5.05 6.47 1.39 363.86 93.16
144 KALV / KalVista Pharmaceuticals, Inc.
KalVista Pharmaceuticals, Inc. is a biopharmaceutical company based in the United States, with a significant operational presence in both Boston, Massachusetts, and Salisbury, England. The company primarily focuses on the discovery, development, and commercialization of small molecule protease inhibitors for diseases with significant unmet medical need. Key projects include a portfolio aimed at treating hereditary angioedema (HAE) and diabetic macular edema (DME), highlighting its specialization in addressing rare diseases and conditions related to diabetes. KalVista's strategy emphasizes advancing these treatments through clinical development to approval, showcasing a commitment to innovation in therapeutic areas where patient options are currently limited.
Mga Paghahanda sa Parmasyutiko 670.79 42.00 20.20 32.30 13.46 139.61 93.09
145 ZURA / Zura Bio Limited Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 125.99 27.30 2.02 13.60 2.04 569.95 93.09
146 IMNM / Immunome, Inc. Mga Paghahanda sa Parmasyutiko 827.06 39.90 20.20 25.06 9.51 163.68 93.08
151 GLUE / Monte Rosa Therapeutics, Inc. Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 296.24 21.00 10.10 16.61 4.80 246.07 93.03
152 RVMD / Revolution Medicines, Inc.
Revolution Medicines, Inc., based in the United States, operates within the biotechnology industry, specifically focusing on developing novel therapies to inhibit frontier cancer targets within notorious cancer pathways. The company's innovative platform is designed to generate small molecules that are tailored to counter elusive, high-value RAS(ON) and mTOR pathway targets. Key projects include advancing a diverse pipeline of drugs aimed at multi-faceted anti-tumor activities. This includes efforts targeting specific mutations and dependencies in RAS and mTOR signaling networks, critical drivers of cancer cells' growth and survival. Revolution Medicines' strategic approach combines deep scientific and clinical development expertise to address the complex challenges presented by these cancer biology areas.
Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 7,096.64 92.40 56.56 73.83 37.97 94.35 93.00
155 CLSK / CleanSpark, Inc.
CleanSpark, Inc. is a US Bitcoin mining company. The Company, through itself and its wholly owned subsidiaries, has operated in the bitcoin mining sector since December 2020. Prior to its work in digital commodities, CleanSpark provided advanced energy technology solutions to commercial and residential customers to solve modern energy challenges in the alternative energy sector.
Mga Serbisyo sa Pananalapi 2,664.48 31.50 17.17 22.23 9.47 134.51 92.96
157 MNMD / Mind Medicine (MindMed) Inc.
Mind Medicine (MindMed) Inc. is a biopharmaceutical company headquartered in New York, USA, focusing on the development of psychedelic-inspired therapies. Established with a vision to address the growing need for innovative mental health treatment options, MindMed is actively engaged in the clinical development of compounds with psychedelic substances like LSD, MDMA, DMT, and an ibogaine derivative, 18-MC. The company's pipeline primarily targets treatment solutions for mental health issues such as anxiety, addiction, and adult ADHD. Among its key projects, MindMed is advancing trials on LSD-experiential therapy for anxiety and an MDMA-like molecule for PTSD, positioning itself as a pioneer in neuropsychiatry by exploring the therapeutic potential of psychedelics in controlled settings.
Bahan Kimia Obat dan Produk Botani 673.13 57.75 16.16 25.50 8.88 187.16 92.92
158 ACRS / Aclaris Therapeutics, Inc.
Aclaris Therapeutics, Inc., based in the United States, operates in the biopharmaceutical industry where it focuses on developing novel drug candidates and technologies to address unmet needs in medical and aesthetic dermatology as well as immunodermatology. The company is particularly acclaimed for its pipeline projects aimed at treating skin disorders like alopecia areata, vitiligo, and common warts. Among their various stages of research and development, Aclaris emphasizes innovation in small molecule therapeutics, seeking to harness scientific advancements to deliver tangible solutions for complex skin conditions. Their strategic approach involves identifying and rapidly advancing a portfolio of proprietary compounds with potential significant commercial prospects in dermatologically related conditions.
Mga Paghahanda sa Parmasyutiko 209.07 16.80 2.02 8.01 1.93 316.32 92.90
159 IMTX / Immatics N.V.
Immatics N.V., based in Germany, operates in the biotechnology sector with a specialized focus on the discovery and development of T cell redirecting cancer immunotherapies. The company leverages its proprietary XPRESIDENT and TCR discovery platforms to identify novel tumor targets and develop T-cell receptor-based therapeutics. Notably, Immatics is advancing a diverse pipeline of treatments through both proprietary and partnered development programs. Key projects include TCR-based therapies such as IMA201 and IMA202, targeting solid tumors, which are in clinical development stages. Immatics aims to transform the clinical landscape of cancer treatment by harnessing the body’s own immune system to fight tumor cells more effectively. This innovative approach positions Immatics N.V. as a prominent player in immunotherapy within the biotech industry.
Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 619.35 21.00 9.09 14.13 5.09 177.41 92.82
161 ERAS / Erasca, Inc. Mga Paghahanda sa Parmasyutiko 446.75 11.55 2.02 5.10 1.57 223.81 92.76
162 GOSS / Gossamer Bio, Inc.
Gossamer Bio, Inc. is a biopharmaceutical company based in the United States, specifically headquartered in San Diego, California. Established with a focus on discovering, acquiring, developing, and commercializing therapeutics in the disease areas of immunology, inflammation, and oncology. Gossamer Bio is actively engaged in multiple clinical trials, primarily aiming to tackle complex diseases with significant unmet medical needs. A key project of theirs includes the development of GB001, a DP2 antagonist intended for the treatment of asthma and other allergic conditions. This initiatives underscores the company's commitment to advancing a diverse portfolio targeted at severe chronic conditions, showcasing its strategic efforts in pushing the boundaries of medical biotechnology.
Mga Paghahanda sa Parmasyutiko 561.49 15.75 1.26 7.90 2.47 219.39 92.73
163 OKUR / OnKure Therapeutics, Inc.
OnKure Therapeutics, Inc. is a U.S.-based biopharmaceutical company focusing on the development of innovative therapies for cancer treatment, particularly targeting novel molecular mechanisms.
Mga Paghahanda sa Parmasyutiko 37.21 35.70 21.21 30.60 2.75 998.74 92.70
164 IDYA / IDEAYA Biosciences, Inc.
IDEAYA Biosciences, Inc., based in the United States, is a biotechnology firm engaged in the discovery and development of targeted therapeutics for oncology. It focuses on precision medicine, aiming to address individual genetic and tumor profiles to optimize patient outcomes. A key area of their research includes synthetic lethality, which targets specific vulnerabilities in cancer cells, allowing for more effective treatments. IDEAYA's portfolio includes several early to mid-stage projects targeting various cancers through small molecule therapies and strategic partnerships with other pharmaceutical entities. This innovative approach seeks to leverage genetic insights to advance cancer treatment, aligning with current trends toward personalized medicine in the healthcare sector.
Mga Paghahanda sa Parmasyutiko 2,151.61 67.20 25.25 45.35 24.55 84.65 92.66
165 BMRN / BioMarin Pharmaceutical Inc.
BioMarin Pharmaceutical Inc., based in the United States, operates within the biotechnology industry, primarily focusing on the development and commercialization of innovative therapies for rare genetic diseases. The company's portfolio includes several FDA-approved products targeting conditions such as Phenylketonuria (PKU), Duchenne muscular dystrophy (DMD), and hereditary angioedema. BioMarin is renowned for its pioneering work in enzyme replacement therapies and its commitment to addressing unmet medical needs where treatment options are limited or non-existent. Key projects involve advancing research in gene therapy, notably their ongoing developments in treatments for hemophilia. This specialization in rare disease markets positions BioMarin as a leader in orphan drugs, contributing significantly to its growth and industry standing.
Mga Paghahanda sa Parmasyutiko 11,187.96 128.10 65.65 98.80 58.27 69.55 92.64
166 ENVX / Enovix Corporation
Enovix Corporation is a U.S.-based company located in Fremont, California. It operates primarily in the energy sector, focusing on the development and manufacturing of advanced silicon-anode lithium-ion batteries. These high-energy-density batteries are designed to significantly enhance storage capacity and efficiency, catering to the demands of modern electronic devices and electric vehicles. A key project for Enovic includes the creation of 3D cell architecture, which aims to improve safety and performance over conventional batteries. Through ongoing development and innovation, Enovix strives to tackle some of the most pressing challenges in battery technology, positioning itself as a leader in next-generation battery solutions.
Miscellaneous Electrical Machinery, Equipment, and Supplies 1,857.22 105.00 10.10 29.89 9.62 210.50 92.63
167 ANRO / Alto Neuroscience, Inc. Mga Paghahanda sa Parmasyutiko 99.63 15.75 4.04 10.54 3.68 186.41 92.61
169 RNAC / Cartesian Therapeutics, Inc.
Cartesian Therapeutics, Inc., based in the United States, operates primarily in the biotechnology sector, focusing on the development of innovative therapeutics. The company stands out for its pioneering work in engineered cell therapies targeting autoimmune diseases, cancer, and respiratory conditions. A significant aspect of Cartesian Therapeutics' approach involves utilizing mRNA technology to modify cells, aiming for more controlled and robust treatment responses. Among its key projects are targeted therapies for myasthenia gravis and acute respiratory distress syndrome, reflecting its commitment to addressing complex medical challenges. The firm leverages cutting-edge scientific methodologies to advance its pipeline, demonstrating a strong commitment to revolutionizing the treatment landscape through biotechnological breakthroughs.
Mga Paghahanda sa Parmasyutiko 261.17 44.10 16.16 37.16 10.05 269.91 92.60
173 CNTA / Centessa Pharmaceuticals plc - Depositary Receipt (Common Stock) Mga Paghahanda sa Parmasyutiko 2,247.07 39.90 27.27 32.54 16.79 93.91 92.57
174 OBIO / Orchestra BioMed Holdings, Inc. Mga Instrumento at Apparatus ng Surgical at Medikal 105.69 21.00 12.12 14.11 2.73 415.90 92.54
175 CRDF / Cardiff Oncology, Inc.
Cardiff Oncology, Inc. is a biotechnology firm based in the United States, specializing in the development of treatment options for cancer patients through its innovative oncology therapeutics. Positioned primarily in the pharmaceutical industry, the company's focal project involves the development of onvansertib, a novel Polo-like Kinase 1 (PLK1) inhibitor designed to target and disrupt key tumor growth pathways, thereby enhancing the efficacy of chemotherapy and targeted therapy. Cardiff Oncology's research and clinical trials aim to provide advancements in the treatment of colorectal cancer, pancreatic cancer, and other types of cancer, striving to meet significant unmet medical needs within the oncology sector. As a pioneer in its field, Cardiff Oncology works closely with regulatory bodies and clinical researchers to ensure the viability and safety of its therapeutic candidates.
Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 139.70 19.95 3.54 10.63 2.10 405.95 92.54
177 CAMP / Camp4 Therapeutics Corporation
CalAmp Corp., based in the United States, operates primarily in the wireless communications industry, delivering comprehensive technology solutions that facilitate critical data connectivity and seamless mobile resource management. Predominantly recognized for its telematics products, the company designs and markets a broad range of devices, including GPS tracking systems and software applications that cater to global businesses seeking efficient fleet management and asset tracking solutions. Key projects emphasize enhancing connectivity within the transportation and automotive sectors, focusing on innovations in IoT (Internet of Things) integration and SaaS (Software as a Service) platforms. CalAmp's strategic initiatives aim to refine real-time information processing and improve operational efficiencies for its diverse clientele, spanning various commercial and government sectors.
Kagamitan sa Pag-broadcast sa Radyo at Telebisyon at Komunikasyon 30.64 18.90 8.08 14.62 1.52 837.18 92.52
180 PYXS / Pyxis Oncology, Inc. Mga Paghahanda sa Parmasyutiko 82.48 8.40 5.05 6.32 1.28 390.23 92.44
181 SGMT / Sagimet Biosciences Inc.
Sagimet Biosciences Inc., based in the United States, operates within the biotechnology industry, focusing primarily on the development of novel therapies for diseases with unmet medical needs, including metabolic and liver diseases. A key project for Sagimet Biosciences is the development of its leading compound, TVB-2640, which targets the fatty acid synthase enzyme implicated in various metabolic pathways. This investigational drug has shown potential in addressing conditions such as nonalcoholic steatohepatitis (NASH), which is a severe liver condition lacking effective treatment options. Their strategic approach combines rigorous scientific research with targeted clinical trials, aiming to provide innovative therapeutic solutions to improve patient outcomes in areas with significant medical needs.
Mga Paghahanda sa Parmasyutiko 241.79 34.65 11.11 26.26 7.51 249.73 92.41
185 BCRX / BioCryst Pharmaceuticals, Inc.
BioCryst Pharmaceuticals, Inc., headquartered in the United States, operates within the biotechnology sector, focusing on the development and commercialization of novel, oral, and small-molecule medicines. The company primarily targets rare diseases where enzyme regulation plays a critical role. Key projects include treatments for hereditary angioedema, a disorder influencing the immune system, and severe malaria. Notably, BioCryst has developed Berotralstat (ORLADEYO®), a prophylactic treatment for hereditary angioedema, significantly reducing the frequency of patient attacks. Additionally, the company is pioneering advancements in antiviral treatments, including therapies for influenza and COVID-19, enhancing its footprint in addressing global health crises through pharmaceutical innovation. This strategic focus on specific, underserved medical needs drives BioCryst’s research and development efforts, positioning it as a notable entity in rare disease therapeutics.
Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 1,743.26 31.50 11.11 17.99 8.31 116.61 92.36
187 AVTX / Avalo Therapeutics, Inc.
Avalo Therapeutics, Inc., headquartered in the United States, operates within the biotechnology industry, focusing primarily on the development of transformative therapies for serious and rare diseases. A key aspect of its project portfolio includes innovative treatments targeting conditions such as autoimmune and rare diseases, where significant unmet medical needs exist. The company employs a robust, science-driven approach that emphasizes genetic insights and novel therapeutic pathways. Avalo Therapeutics' dedication to leveraging cutting-edge science to design and develop medications positions it distinctively for advancing treatments that can substantively improve patient outcomes in underserved medical areas, aligning its strategic initiatives with long-term health solutions and likely growth in its biotechnological endeavors.
Mga Paghahanda sa Parmasyutiko 100.68 50.40 15.15 31.47 9.29 241.93 92.36
189 PRAX / Praxis Precision Medicines, Inc. Mga Paghahanda sa Parmasyutiko 954.66 283.50 33.33 105.40 45.54 131.85 92.35
190 CMPS / COMPASS Pathways plc - Depositary Receipt (Common Stock)
COMPASS Pathways plc is a health care company based in the United Kingdom, primarily focusing on the biotechnology industry. It specializes in developing therapies that address unmet needs within mental health care. COMPASS Pathways is notably recognized for its pioneering research in psilocybin therapy and its potential applications in treatment-resistant depression. One of their key projects is COMP360, a proprietary formulation of synthetic psilocybin, now advancing through clinical trials aimed at evaluating its safety and effectiveness. The company's efforts are part of a broader aim to innovate within psychiatric treatment modalities, contributing to evidence-based solutions that can significantly impact global mental health treatment paradigms.
Mga Paghahanda sa Parmasyutiko 412.72 42.00 6.06 15.20 4.42 244.63 92.34
191 FOLD / Amicus Therapeutics, Inc.
Amicus Therapeutics, Inc. is a biotechnology company based in the United States, focused primarily on the discovery, development, and delivery of novel treatments for rare metabolic diseases. Founded in 2002 and headquartered in Cranbury, New Jersey, the company specializes in therapies that target unique diseases driven by genetic mutations. A significant project includes the development of migalastat, marketed under the name Galafold, which treats individuals with Fabry disease through an oral medication alternative to traditional enzyme replacement therapies. Additionally, Amicus is actively involved in advancing a pipeline that addresses other rare diseases, such as Pompe disease and Epidermolysis Bullosa, deploying innovative protein engineering and gene therapy technologies to cater to unmet medical needs in these patient populations.
Mga Paghahanda sa Parmasyutiko 2,335.13 23.10 9.09 16.22 7.59 113.96 92.34
192 CBLL / CeriBell, Inc. 432.97 37.80 29.29 32.44 11.83 174.18 92.31
194 ABSI / Absci Corporation Komersyal na Pisikal at Biyolohikal na Pananaliksik 315.36 10.50 5.95 8.29 2.39 246.12 92.29
195 IMUX / Immunic, Inc.
Immunic, Inc., based in the United States, is a biopharmaceutical company specialized in the development of treatments for chronic inflammatory and autoimmune diseases. The company, established with a focus on novel therapeutics, is actively engaged in advancing its pipeline of selective oral immunology therapies. Among its prominent projects is the development of IMU-838, a next-generation selective immune modulator that targets diseased-activated immune cells while leaving normal cells unharmed. This therapy is being explored in multiple Phase 2 and Phase 3 clinical trials for conditions such as multiple sclerosis, ulcerative colitis, and Crohn's disease. By prioritizing these potent, orally available compounds, Immunic aims to address unmet medical needs in autoimmune and inflammatory diseases.
Mga Paghahanda sa Parmasyutiko 80.89 10.50 4.04 7.96 0.82 875.96 92.28
196 SKYE / Skye Bioscience, Inc. Mga Paghahanda sa Parmasyutiko 108.46 21.00 10.10 15.30 3.50 339.02 92.27
197 AVBP / ArriVent BioPharma, Inc. Mga Paghahanda sa Parmasyutiko 717.19 47.25 32.32 39.58 19.12 106.88 92.26
199 ORIC / ORIC Pharmaceuticals, Inc.
ORIC Pharmaceuticals, Inc., based in the United States, operates within the biotechnology sector, primarily focusing on the development of treatments aimed at overcoming resistance mechanisms in cancer. The company has undertaken significant projects targeting multiple resistance pathways with its flagship programs including ORIC-101 and ORIC-533. ORIC-101, which targets the glucocorticoid receptor, is advancing through clinical trials to tackle solid tumors. ORIC-533, an orally bioavailable small molecule inhibiting CD73, is designed to enhance immune response against tumors. ORIC Pharmaceuticals leverages a science-driven approach to address therapeutic resistance and relapse, positioning itself in critical areas of oncology research and addressing unmet medical needs in cancer treatment.
Mga Paghahanda sa Parmasyutiko 881.70 26.25 12.12 18.46 10.23 80.47 92.23
200 ACET / Adicet Bio, Inc.
Adicet Bio, Inc. is a biotechnology company based in the United States, specifically focused on the development of therapies in the field of oncology. The company leverages its proprietary gamma delta T cell platform to engineer allogeneic cell therapies aimed at enhancing the immune system's ability to recognize and eradicate cancers more effectively. Key to their project portfolio is the advancement of CAR-T cell therapies, an area where they're engaged in pioneering work to innovate treatments that offer specificity to various cancer antigens. Adicet Bio's research and development efforts are particularly directed towards enhancing cell-mediated immune recognition of tumors, demonstrating their commitment to addressing unmet medical needs within the oncology sector. Their approach underscores a promising shift towards potentially more efficacious and accessible cancer treatments.
Mga Paghahanda sa Parmasyutiko 59.94 8.40 4.04 6.12 0.72 750.00 92.21
203 TARA / Protara Therapeutics, Inc.
Protara Therapeutics, Inc., based in the United States, operates within the biotechnology industry, focusing on developing treatments for rare and specialized conditions. The company is engaged in rigorous scientific research to address unmet medical needs, particularly in oncology and rare disease sectors. Its key projects include TARA-002, an investigational therapy for lymphatic malformations, which is a primary focus of its clinical development efforts. Additionally, Protara is actively involved in the development of Intravenous (IV) Choline Chloride, a product designed to treat intestinal failure-associated liver disease (IFALD) in patients receiving parenteral nutrition. Through these projects, Protara aims to deliver novel therapeutics that significantly improve patient outcomes.
Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 120.38 31.50 21.21 24.48 3.12 687.14 92.16
204 TYRA / Tyra Biosciences, Inc. Mga Paghahanda sa Parmasyutiko 674.73 34.65 28.28 30.75 12.67 142.57 92.08
207 GANX / Gain Therapeutics, Inc. Mga Paghahanda sa Parmasyutiko 60.93 12.60 5.05 7.99 1.99 303.53 92.03
208 QFIN / Qfin Holdings, Inc. - Depositary Receipt (Common Stock) Mga Serbisyo sa Pananalapi 3,855.67 61.42 40.40 52.61 29.12 80.68 92.03
209 DIDIY / DiDi Global Inc. - Depositary Receipt (Common Stock)
DiDi Global Inc., based in China, is a prominent player in the mobility technology sector, providing a broad range of app-based transportation services, including ride-hailing, taxi hailing, chauffeur services, and carpooling, along with micro-mobility services such as bike-sharing. In addition to transport solutions, DiDi extends into autonomous driving, artificial intelligence, and financial services. A pivotal project for DiDi has been the advancement of autonomous driving technologies, aimed at enhancing the safety and efficiency of urban transport systems. This initiative reflects its strategic focus on leveraging technology to optimize transportation infrastructure, which remains central to its business model and expansion strategy. DiDi's broad-scope operations underline its role as a significant innovator in the global transportation industry.
20,558.51 7.56 6.06 6.80 4.31 92.00
210 DAWN / Day One Biopharmaceuticals, Inc. Mga Paghahanda sa Parmasyutiko 769.26 35.70 16.16 23.46 7.51 212.38 91.97
211 ELDN / Eledon Pharmaceuticals, Inc.
Eledon Pharmaceuticals, Inc., based in the United States, operates within the healthcare sector, specifically focusing on the biotechnology industry. The company is primarily engaged in developing therapeutic treatments aimed at addressing immune and inflammatory conditions, with a strong emphasis on innovative organ and cellular transplantation, autoimmune diseases, and neurodegenerative disorders. Key projects include the advancement of their lead compound, tegoprubart, which targets critical pathways involved in inflammation and immune responses. Eledon Pharmaceuticals is actively pursuing clinical trials to explore and expand the potential applications of their technologies, seeking to offer novel solutions for complex medical conditions that currently have limited treatment options.
Mga Paghahanda sa Parmasyutiko 155.09 12.60 8.08 9.79 2.59 278.07 91.96
212 NAMS / NewAmsterdam Pharma Company N.V.
NewAmsterdam Pharma Company N.V. is a biopharmaceutical enterprise based in the Netherlands, primarily concentrated on the development of therapies aimed at cardiometabolic diseases. The company is known for its innovative approach in the pharmaceutical industry, focusing on developing treatments that address the underlying causes of cardiovascular and metabolic disorders. A key project that encapsulates the company’s strategic focus is the development of a novel cholesterol-lowering drug designed to reduce the risk of cardiovascular diseases significantly. This particular initiative is pivotal as it targets a prevalent health issue with a large, unmet medical need, potentially positioning NewAmsterdam Pharma as a key player in the global market for preventative cardiovascular treatment solutions.
Mga Paghahanda sa Parmasyutiko 2,704.74 52.50 27.27 42.38 24.05 76.27 91.96
213 NKTX / Nkarta, Inc. Mga Paghahanda sa Parmasyutiko 150.57 18.90 8.08 12.65 2.12 495.20 91.91
216 ACLX / Arcellx, Inc. Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 3,841.65 140.70 101.00 115.33 69.39 66.23 91.87
217 ATAI / Atai Life Sciences N.V.
Atai Life Sciences N.V., headquartered in the Netherlands, operates primarily within the biotechnology sector, specializing in the development of treatments for mental health disorders. The company employs a unique approach by focusing on psychedelic and non-psychedelic compounds to innovate solutions for conditions that are typically resistant to conventional therapies. A key pillar of Atai Life Sciences' work revolves around leveraging advanced scientific research to demystify and effectively target the underlying biological mechanisms of mental illnesses. Central to their mission, Atai invests in a diverse portfolio of therapeutic projects that explore novel drug development pathways, including the exploration of psilocybin and other compounds, to address significant unmet medical needs in the psychiatric space, aiming at revolutionizing the mental health treatment landscape.
Mga Paghahanda sa Parmasyutiko 969.96 16.80 7.07 11.51 4.58 151.89 91.86
220 ARDX / Ardelyx, Inc.
Ardelyx, Inc. is a biopharaceutical company based in the United States, specifically headquartered in Fremont, California. The company operates primarily within the healthcare sector with a focus on innovating and developing first-in-class medicines for the treatment of renal and gastrointestinal diseases. Ardelyx's key projects include the development of tenapanor, which is a pioneering treatment designed to manage hyperphosphatemia in patients with chronic kidney disease on dialysis. This proprietary drug directly targets the issue of elevated phosphate levels looking to improve patient outcomes significantly. The company is also actively involved in advancing a pipeline of other novel compounds that address similar conditions in underserved patient populations, demonstrating Ardelyx’s commitment to addressing complex clinical challenges through targeted therapies.
Mga Paghahanda sa Parmasyutiko 1,531.27 15.75 8.08 11.41 6.36 79.33 91.77
221 ABOS / Acumen Pharmaceuticals, Inc. Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 82.08 11.55 4.04 7.96 1.36 487.16 91.74
223 SANA / Sana Biotechnology, Inc. Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 704.21 12.60 5.05 8.84 3.06 189.36 91.66
225 SPRY / ARS Pharmaceuticals, Inc. Mga Paghahanda sa Parmasyutiko 1,145.88 42.00 28.28 32.64 11.62 181.14 91.63
227 ARTV / Artiva Biotherapeutics, Inc. 77.33 19.95 10.10 15.71 3.15 395.52 91.61
228 FRPT / Freshpet, Inc.
Freshpet, Inc. is a U.S.-based company operating within the consumer goods sector, specifically focusing on the production and distribution of fresh, refrigerated food for pets. Established with the mission to improve the quality of pet food by using natural and fresh ingredients, Freshpet, Inc. has aggressively expanded its presence through innovative refrigerated products tailored for companion animals. Key projects by the company include the development of its Freshpet Kitchens 2.0, an advanced manufacturing plant in Ennis, Texas aimed at boosting production capacities and reducing operational costs. Freshpet's strategic initiatives focus on sustainability and the enhancement of supply chain efficiencies, thereby reaffirming its commitment to providing high-quality, fresh food options for pets while pursuing environmental and operational stewardship.
Grain Mill Products 2,720.84 165.90 65.65 96.98 55.82 73.86 91.57
229 LKNCY / Luckin Coffee Inc. - Depositary Receipt (Common Stock)
Luckin Coffee Inc., based in China, operates predominantly in the coffee retail industry. The company has rapidly expanded its market presence by establishing numerous coffee outlets across China, aiming to rival other leading coffee chains through a technology-driven approach and an innovative business model. Central to its strategy is a focus on mobile app-based purchasing, which seamlessly integrates with its substantial offline network of pick-up locations and delivery services, optimizing customer convenience and operational efficiency. This approach underpins Luckin Coffee's project emphasis on digital integration and market penetration. Despite facing regulatory challenges and market fluctuations, Luckin Coffee continues to pursue aggressive growth and technological enhancements to solidify its position in the competitive coffee industry landscape.
Restaurants, Dining, Eating And Drinking Places 5,786.51 50.92 40.41 44.81 18.05 91.57
230 BRZE / Braze, Inc.
Braze, Inc., based in the United States, operates within the software industry, primarily focusing on customer engagement technology that enables businesses to enhance their marketing strategies. The company specializes in developing a comprehensive platform that integrates data collection, analysis, and actionable insights to facilitate personalized messaging and optimization of customer interactions across mobile, web, email, and direct communication channels. Key projects of Braze involve advanced automation and artificial intelligence to refine clients' engagement strategies, consistently emphasizing real-time, behavior-based communications that aim to boost customer retention and conversion rates. Braze supports a diverse clientele ranging from startups to global enterprises, adapting to various sectors by providing scalable solutions that drive tangible business outcomes.
Naka-prepack na Software 2,905.34 71.40 35.35 45.42 27.70 63.94 91.53
231 MLYS / Mineralys Therapeutics, Inc. Mga Paghahanda sa Parmasyutiko 1,017.43 50.40 15.15 36.98 15.48 138.86 91.53
235 VTYX / Ventyx Biosciences, Inc. Mga Paghahanda sa Parmasyutiko 170.61 22.05 2.02 11.22 2.40 368.48 91.43
237 IFRX / InflaRx N.V.
InflaRx N.V., based in Jena, Germany, operates in the biopharmaceutical domain, primarily focusing on the development of innovative therapies for inflammatory diseases by targeting the complement system, a key element of the human immune response. The company's hallmark initiative revolves around its lead product candidate, IFX-1, an anti-C5a antibody, which shows promise across various clinical trials for treating diseases such as hidradenitis suppurativa, ANCA-associated vasculitis, and other inflammatory conditions. Furthermore, InflaRx has expanded its pipeline to explore additional compounds and targets with potential therapeutic applications in inflammatory diseases, thereby solidifying its mission to address unmet medical needs through pioneering complement-related therapeutic interventions.
Mga Paghahanda sa Parmasyutiko 107.38 10.50 2.02 4.37 1.60 175.80 91.42
238 NGNE / Neurogene Inc. Mga Paghahanda sa Parmasyutiko 262.55 73.50 26.26 48.35 18.48 162.76 91.40
239 CGON / CG Oncology, Inc. Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 2,045.30 86.10 40.40 64.13 26.82 139.03 91.40
240 ZVRA / Zevra Therapeutics, Inc. Mga Paghahanda sa Parmasyutiko 497.96 30.45 18.18 24.19 9.07 167.57 91.40
241 ACVA / ACV Auctions Inc. Mga Serbisyo sa Negosyo, Hindi Nauuri sa Ibang Lugar 2,000.38 28.88 11.62 20.27 11.66 74.01 91.31
242 BMEA / Biomea Fusion, Inc.
Biomea Fusion berfokus pada penemuan, pengembangan, dan komersialisasi molekul kecil ireversibel untuk mengobati pasien dengan kanker yang terdefinisi secara genetik.
Mga Paghahanda sa Parmasyutiko 113.64 16.80 3.03 7.82 1.95 300.00 91.30
243 CNTX / Context Therapeutics Inc.
Context Therapeutics Inc. is a biotechnology company based in the United States. The company primarily focuses on developing advanced treatments for hormone-driven cancers, including breast and gynecologic cancers. Its key projects involve the advancement of small molecule and immunotherapy treatments that aim to modulate tumor and immune cell signaling within the tumor microenvironment. Context Therapeutics' flagship project is onapristone extended release (ONA-XR), a progesterone receptor antagonist in clinical trials for various types of cancer. The research pipeline further includes collaborations targeting other novel mechanisms and treatment modalities that complement the company’s central mission to improve outcomes in cancer treatment with a specific emphasis on women's health.
Mga Paghahanda sa Parmasyutiko 76.45 10.50 4.04 6.12 0.84 627.71 91.30
244 TECX / Tectonic Therapeutic, Inc. 476.22 106.05 64.64 81.31 25.54 219.48 91.29
245 EOLS / Evolus, Inc.
Evolus, Inc., based in the United States, is a prominent player in the medical aesthetics market. The company specializes in the development, manufacturing, and commercialization of innovative performance beauty products. A key project and flagship product of Evolus is Jeuveau®, a proprietary formulation of prabotulinumtoxinA-xvfs, which is a botulinum toxin type A product approved by the FDA and other international regulatory bodies, aimed at temporarily improving the appearance of facial wrinkles. This product positions Evolus as a direct competitor in the global aesthetics market, particularly challenging the dominance of established brands with its focus on technology-driven aesthetic solutions. The company’s strategic market positioning and investment in next-generation products underscore its commitment to growth and innovation in the cosmetic treatment landscape.
Mga Paghahanda sa Parmasyutiko 493.20 23.10 17.17 19.82 7.63 159.39 91.27
246 EVH / Evolent Health, Inc.
Evolent Health, Inc., based in the United States, operates within the healthcare sector, primarily focused on providing an integrated, value-based care platform to payers and providers. The company aids its partners in driving high-quality, lower-cost care by delivering comprehensive clinical and administrative solutions. Evolent Health’s key projects typically involve assisting organizations in transitioning from fee-for-service to value-based care models. This includes offering software, analytics, and clinical technology services that help manage risk and improve patient outcomes. Their strategic approach not only supports the operational needs of healthcare entities but also aligns with evolving regulatory and reimbursement frameworks, thereby facilitating a more sustainable and efficient healthcare system.
Mga Serbisyo sa Pamamahala 1,118.77 49.57 9.09 18.30 9.65 89.91 91.19
247 ABEO / Abeona Therapeutics Inc.
Abeona Therapeutics Inc., based in the United States, is a biopharmaceutical company focused principally on the development of gene and cell therapies for severe and life-threatening rare diseases. A key project of Abeona includes its involvement in developing advanced therapies for diverse genetic disorders, prominently its work on treatments for Sanfilippo syndrome and Recessive Dystrophic Epidermolysis Bullosa (RDEB). These projects employ cutting-edge technology such as AAV-based gene therapy platforms, aiming to address unmet medical needs in conditions that currently have limited treatment options. Abeona's dedication to pioneering novel therapies continues to address critical gaps in healthcare for genetically driven conditions.
Mga Paghahanda sa Parmasyutiko 350.54 28.88 14.14 20.91 6.83 205.70 91.19
248 RZLT / Rezolute, Inc. Mga Paghahanda sa Parmasyutiko 430.76 15.75 9.09 13.37 7.12 87.96 91.19
250 AQST / Aquestive Therapeutics, Inc. Mga Paghahanda sa Parmasyutiko 374.56 15.75 4.80 8.59 3.77 127.72 91.15
252 TECK / Teck Resources Limited
Teck Resources Limited, based in Canada, operates primarily in the mining and mineral development sector with significant focuses on steelmaking coal, copper, zinc, and energy. It stands as one of the world's leading mining companies, with major development projects like the Quebrada Blanca Phase 2 in Chile aimed at significantly increasing their copper production. The company also runs diversified operations in the Elk Valley of British Columbia, which emphasizes steelmaking coal. Moreover, Teck's involvement in the oil sands project in Alberta showcases its interests in the energy domain. The integration of various resource segments, along with a commitment to sustainability and technological adaptation, forms the core of Teck Resources Limited's operational and strategic framework.
Pagmimina At Pag-quarry Ng Nonmetallic Minerals, Maliban sa Mga Gatong 16,826.63 75.60 55.09 63.12 34.19 84.55 91.13
253 IPSC / Century Therapeutics, Inc. Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 42.44 7.35 2.02 4.34 0.49 781.64 91.13
254 GNLX / Genelux Corporation Mga Paghahanda sa Parmasyutiko 123.55 32.55 10.10 20.40 3.33 516.31 91.10
255 GHRS / GH Research PLC
GH Research PLC is a clinical-stage biopharmaceutical company dedicated to transforming the treatment of psychiatric and neurological disorders. GH Research PLC's initial focus is on developing its novel and proprietary 5-MeO-DMT therapies for the treatment of patients with Treatment-Resistant Depression.
Mga Paghahanda sa Parmasyutiko 833.68 42.00 25.25 33.51 13.50 149.36 91.10
258 ZBIO / Zenas BioPharma, Inc. 672.58 47.25 19.19 32.35 16.00 102.43 91.05
260 ELVN / Enliven Therapeutics, Inc. Mga Paghahanda sa Parmasyutiko 1,197.55 54.60 33.33 42.08 20.27 108.09 91.04
261 IRON / Disc Medicine, Inc. Mga Paghahanda sa Parmasyutiko 2,068.86 138.60 85.85 101.72 59.64 70.59 91.04
264 EH / EHang Holdings Limited - Depositary Receipt (Common Stock) Suku Cadang Pesawat Terbang dan Peralatan Bantu, Tidak Diklasifikasikan di Tempat Lain 1,144.18 31.92 20.20 26.78 15.83 69.37 91.00
268 RCKT / Rocket Pharmaceuticals, Inc.
Rocket Pharmaceuticals, Inc., headquartered in the United States, is at the forefront of the biotechnological industry, specializing in the development of gene therapies. The company is primarily engaged in pioneering advanced treatments for rare and devastating genetic diseases. Among its key projects are gene therapy platforms targeting disorders like Fanconi anemia, Leukocyte Adhesion Deficiency-I, and Pyruvate Kinase Deficiency. These therapeutic platforms employ cutting-edge technologies including lentiviral and adeno-associated viral vectors, representing transformative advances in gene therapy aimed at correcting severe genetic disorders at their root cause. Rocket Pharmaceuticals is committed to rigorous clinical trials and scientific research to ensure the efficacy and safety of its therapies, aiming to provide long-term solutions for conditions with limited treatment options.
Mga Paghahanda sa Parmasyutiko 353.86 16.80 2.02 8.08 3.28 146.39 90.92
269 JSPR / Jasper Therapeutics, Inc. Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 45.41 26.25 4.04 15.45 2.80 451.63 90.92
272 ARVN / Arvinas, Inc. Mga Paghahanda sa Parmasyutiko 565.84 22.05 7.07 13.32 7.73 72.54 90.89
274 KYTX / Kyverna Therapeutics, Inc. Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 160.01 26.25 5.05 17.54 3.71 374.16 90.87
275 CADL / Candel Therapeutics, Inc. Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 318.36 26.25 13.13 21.08 5.79 263.45 90.85
276 ARWR / Arrowhead Pharmaceuticals, Inc.
Arrowhead Pharmaceuticals, Inc. is a biopharmaceutical company based in the United States, specifically headquartered in Pasadena, California. It operates primarily within the healthcare sector, focusing on developing medicines that treat intractable diseases by silencing the genes that cause them. Arrowhead’s research and development strategy involves leveraging its proprietary RNA interference (RNAi) technology to create drugs that precisely silence or eliminate genetic expressions contributing to disease processes. Notable projects include therapies targeting various diseases such as AAT liver disease, chronic hepatitis B, and inherited diseases with limited treatment options. The company's innovative approach reflects a broader trend in biotech towards targeted genetic interventions.
Mga Paghahanda sa Parmasyutiko 3,043.31 84.00 17.17 44.88 22.03 103.72 90.84
277 ADCT / ADC Therapeutics SA Mga Paghahanda sa Parmasyutiko 345.37 10.50 5.05 8.42 3.07 174.10 90.83
279 CTMX / CytomX Therapeutics, Inc.
CytomX Therapeutic, Inc., headquartered in the United States, operates primarily within the biotechnology industry, focusing on developing a class of transformative cancer treatments based on its proprietary Probody® technology platform. This platform innovatively enhances the targeting and safety profile of cancer antibodies and antibody-drug conjugates by allowing them to activate specifically within the tumor microenvironment, thus aiming to decrease damage to healthy tissues. Key projects include collaborative efforts with industry giants such as Bristol-Myers Squibb and AbbVie, emphasizing CytomX’s engagement in co-developing next-generation oncology drugs. These projects have significant implications for the advancement of targeted therapies in oncology, propelling CytomX as a notable player in cancer biotherapeutics.
Mga Paghahanda sa Parmasyutiko 336.42 8.40 3.54 5.86 2.04 186.10 90.83
281 BNTC / Benitec Biopharma Inc.
Benitec Biopharma Inc. is a biotechnology firm based in the United States, specifically focused within the healthcare sector. The company is pioneering in the development of genetic medicines, utilizing its proprietary gene-silencing technology, ddRNAi (DNA-directed RNA interference), to create therapies that target and potentially silence disease-causing genes. Benitec's pipeline primarily addresses conditions for which conventional treatments are inadequate. Noteworthy projects include therapeutics aimed at chronic and inherited diseases, such as oculopharyngeal muscular dystrophy (OPMD) and chronic hepatitis B. These innovative gene therapy projects position Benitec Biopharma as a key player in the field of genetic medicine, striving to offer novel solutions to complex medical challenges.
Mga Paghahanda sa Parmasyutiko 337.98 36.75 17.17 26.23 13.24 98.25 90.73
283 ACHV / Achieve Life Sciences, Inc.
Achieve Life Sciences, Inc., based in the United States, operates within the biopharmaceutical industry focused on developing and commercializing novel treatments for addiction and related disorders. One of its key projects involves the development of cytisinicline, a plant-based alkaloid with a high-binding affinity to the nicotinic acetylcholine receptor, aimed at aiding smoking cessation. This compound represents a significant breakthrough in addressing nicotine addiction, offering a potential alternative to traditional therapies with a differing mechanism of action. Life Sciences is advancing its clinical development, actively engaging in multiple phase 3 trials to further evaluate the efficacy and safety of cytisinicline for broad therapeutic use.
Mga In Vitro at In Vivo Diagnostic Substances 148.06 26.25 10.10 16.32 2.98 446.73 90.69
284 TERN / Terns Pharmaceuticals, Inc. Mga Paghahanda sa Parmasyutiko 608.35 35.70 7.58 18.58 6.96 167.13 90.69
285 AURA / Aura Biosciences, Inc. Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 389.50 24.15 19.19 21.62 6.26 244.61 90.66
286 OVID / Ovid Therapeutics Inc.
Ovid Therapeutics Inc., based in the United States, operates within the biopharmaceutical industry and is primarily engaged in developing therapies that target rare neurological disorders. The company's research pipeline includes several innovative projects focusing on addressing significant unmet medical needs. A key project is the development of OV101 (gaboxadol), a treatment aimed at conditions such as Angelman syndrome and Fragile X syndrome, leveraging its potential to modulate GABA receptors in the brain. Another significant endeavor involves their collaboration on developing OV329, a GABA aminotransferase inhibitor, for treatment-resistant epilepsy. Ovid Therapeutics continues to collaborate with academic and corporate entities, aiming to push the boundaries of neuroscience and improve the quality of life for patients with debilitating neurological conditions.
Mga Paghahanda sa Parmasyutiko 91.02 5.78 1.52 3.47 1.28 172.86 90.61
287 CGEN / Compugen Ltd. Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 131.42 13.65 4.04 7.14 1.41 408.19 90.60
289 NKTR / Nektar Therapeutics
Nektar Therapeutics is a biopharmaceutical company based in the United States, specifically in San Francisco, California. Specializing in the development of new drug candidates that utilize its proprietary biopolymer chemistry technology, the company focuses its efforts on therapeutic areas such as oncology, pain management, and auto-immune diseases. One of its notable projects includes the development of NKTR-214 (bempegaldesleukin), a CD122-preferential IL-2 pathway agonist designed to stimulate the immune system and enhance the effectiveness of cancer immunotherapy. Nektar also works extensively in advancing treatments for chronic pain conditions, exemplifying its strategic integration of novel science and technology to address unmet medical needs in critical therapeutic divisions.
Mga Paghahanda sa Parmasyutiko 567.89 126.00 69.69 98.09 29.86 228.81 90.49
290 OCS / Oculis Holding AG
Oculis Holding AG is a biopharmaceutical company based in Switzerland, primarily engaged in the development of treatments for ophthalmic diseases. With a strong focus on innovation in ocular therapies, the company aims to address the unmet needs of patients suffering from eye conditions. Among its notable projects, Oculis is pioneering technologies to enhance the delivery of drugs directly to the eye, potentially offering non-invasive alternatives to current treatments that often require injections. Key areas of their research include therapies for diabetic macular edema and other severe eye diseases, positioning them at the forefront of ocular therapeutic development in the biopharmaceutical industry.
Mga Paghahanda sa Parmasyutiko 846.53 52.50 28.28 37.01 16.13 128.82 90.49
292 CRSP / CRISPR Therapeutics AG
CRISPR Therapeutics AG, based in Switzerland, operates within the biotechnology industry, primarily focusing on the development of gene-based medicine leveraging the CRISPR/Cas9 gene-editing platform. The company has ventured into strategic collaborations to enhance the breadth of its therapeutic programs, notably in areas such as immuno-oncology and rare diseases. A signature project includes its partnership with Vertex Pharmaceuticals, aimed at advancing CTX001, a therapy for the treatment of transfusion-dependent beta-thalassemia and severe sickle cell disease. CRISPR Therapeutics' approach emphasizes transformative gene-editing therapies that position it at the forefront of genetic medicine, aiming to provide substantial solutions for previously intractable diseases through direct genetic modification.
Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 4,579.23 281.40 32.32 81.06 51.83 56.43 90.47
293 DUOL / Duolingo, Inc. Naka-prepack na Software 13,648.86 630.00 357.54 484.89 297.86 62.71 90.46
294 CRVS / Corvus Pharmaceuticals, Inc.
Corvus Pharmaceuticals, Inc., headquartered in Burlingame, California, USA, operates primarily within the biotechnology sector, focusing on the development and commercialization of innovative immunotherapy treatments. The company is engaged in pioneering research aimed at harnessing the immune system to combat cancer and autoimmune diseases. Key projects include CPI-006, a potent humanized monoclonal antibody which shows promise in enhancing immune responses against various cancers, and CPI-818, designed to inhibit ITK, which plays a critical role in the proliferation of T-cells in certain lymphomas. Other important initiatives involve the development of small molecule and antibody technologies targeting renal cell carcinoma and other advanced malignancies. This strategic focus on immuno-oncology positions the company as a potential leader in novel cancer treatment modalities.
Mga Paghahanda sa Parmasyutiko 427.71 25.20 11.11 15.10 5.74 162.77 90.45
296 AKRO / Akero Therapeutics, Inc.
Akero Therapeutics, Inc., based in the United States, operates in the biotechnology industry, focusing primarily on developing innovative treatments for serious metabolic diseases. A key project for the company is its work on non-alcoholic steatoheepatitis (NASH), a severe liver disease. One of their prominent drugs in development, efruxifermin (EFX), has shown promising results in early clinical trials, particularly in improving liver health and other metabolic outcomes in NASH patients. Akero Therapeutics employs a data-driven approach in its research and development efforts, aiming to address critical unmet medical needs and improve patient outcomes. The company's strategic initiatives involve progressing through clinical trials and seeking regulatory approvals to bring new therapeutic solutions to market.
Mga Paghahanda sa Parmasyutiko 3,734.62 114.45 60.60 78.45 46.73 67.87 90.43
299 RVPH / Reviva Pharmaceuticals Holdings, Inc.
Reviva Pharmaceuticals is a clinical stage pharmaceutical company developing therapies that address unmet medical needs in the areas of central nervous system, cardiovascular, metabolic, and inflammatory diseases. Reviva's primary focus is developing its lead product candidate, RP5063 (brilaroxazine), for the treatment of schizophrenia, bipolar disorder, and major depressive disorder.
Mga Paghahanda sa Parmasyutiko 30.70 16.80 2.02 8.60 0.45 1,804.56 90.36
300 ACIU / AC Immune SA
AC Immune SA is a biopharmaceutical company based in Switzerland, primarily engaged in the research and development of novel therapies for neurodegenerative diseases, with a significant focus on Alzheimer’s disease, Parkinson’s disease, and Down syndrome. Leveraging its proprietary technology platforms, including SupraAntigen and Morphomer, the company is deeply involved in developing therapeutic and diagnostic products aimed at enhancing life quality and halting the progression of neurodegenerative diseases. Key projects include ACI-35.030 for Alzheimer's, designed to target pathological tau proteins, and semorinemab, a treatment aimed at moderate Alzheimer's disease. The company collaborates extensively with global pharmaceutical entities and academic institutions to advance its clinical programs.
Mga Paghahanda sa Parmasyutiko 206.80 12.60 7.07 9.18 2.04 346.72 90.35
301 MNKD / MannKind Corporation
MannKind Corporation, based in the United States, primarily operates within the biopharmaceutical sector, focusing on the development and commercialization of therapeutic products for diseases such as diabetes. A key product of MannKind is Afrezza, an inhalable insulin that offers a distinctive mode of administration compared to traditional insulin injections, targeting a broad diabetic patient base seeking less invasive treatment options. Additionally, the company is involved in the development of novel therapeutic platforms including Technosphere, a technology designed for pulmonary drug delivery that represents a significant part of their research and development efforts. Leveraging its proprietary technology, MannKind aims to expand its portfolio and address significant unmet medical needs in various therapeutic areas.
Mga Paghahanda sa Parmasyutiko 1,407.60 12.60 7.07 9.44 4.59 105.33 90.35
302 INSP / Inspire Medical Systems, Inc.
Inspire Medical Systems, Inc., based in the United States, operates within the healthcare sector, specifically focusing on medical devices designed for the treatment of obstructive sleep apnea (OSA). Established with technology developed at the University of Minnesota, the company has carved a niche for itself by innovating and commercializing the Inspire therapy system, which is an FDA-approved, implantable device offering an alternative to traditional CPAP machines. This system functions by delivering mild stimulation to key airway muscles during sleep, thus ensuring the airway remains open without the discomfort of external devices. Inspire Medical Systems has been instrumental in advancing sleep apnea treatment, enhancing patient comfort, and improving adherence rates, reflecting a blend of medical innovation and practical application that addresses significant unmet needs in sleep medicine.
Mga Instrumento at Apparatus ng Surgical at Medikal 2,770.36 241.50 102.01 151.20 93.69 61.33 90.33
303 IBRX / ImmunityBio, Inc.
ImmunityBio, Inc., based in the United States, operates within the biotechnology sector, focusing on innovating immunotherapy platforms that engage the immune system's natural capabilities to fight cancer and infectious diseases. The company has been pivotal in developing therapies that address both the innate and adaptive arms of the immune system. One of the key projects of ImmunityBio includes their work on a novel cancer vaccine targeting multiple tumor types, which aims to enhance patient outcomes by inducing robust immune responses against cancer cells. Additionally, ImmunityBio has expanded its research ambit to include the development of treatments for COVID-19, aiming to create long-lasting immunity against the virus. Through these projects, ImmunityBio strives to offer transformative therapeutic options for life-threatening diseases.
Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 2,133.41 25.20 5.05 10.40 2.34 344.62 90.33
304 SVRA / Savara Inc.
Savara Inc. is a specialty pharmaceutical company based in the United States, primarily engaged in the development and commercialization of novel therapies for the treatment of rare respiratory diseases. A key project for Savara is Molgradex, an inhaled formulation of recombinant human granulocyte-macrophage colony-stimulating factor (GM-CSF) intended for the treatment of autoimmune pulmonary alveolar proteinosis (aPAP). This project represents Savara's commitment to addressing unmet needs within niche patient populations by targeting the underlying causes of these conditions rather than merely managing symptoms. As of 2023, the company continues to focus on advancing its clinical development pipeline to fulfill its mission of transforming the lives of patients with serious and life-shortening respiratory diseases.
Mga Paghahanda sa Parmasyutiko 691.06 16.80 5.05 8.52 3.28 159.49 90.29
311 GLOB / Globant S.A.
Globant S.A. is a technology services company based in Luxembourg, specializing in software development, IT services, and consulting. Founded in 2003 in Argentina, Globant has grown to become a significant player in the digital and cognitive transformation arenas, serving clients globally with a focus on reinforcing core technology, building scalable platforms, and enhancing customer experience. Key projects often involve innovations in areas such as artificial intelligence, data analytics, and user experience design across diverse industries including finance, healthcare, and media. Globant's emphasis on creating digital journeys and sustainability solutions demonstrates its commitment to staying at the forefront of technological advancements and addressing complex client challenges effectively.
Mga Serbisyo sa Pagproseso ng Computer at Paghahanda at Pagproseso ng Data 2,979.48 180.72 74.74 109.66 67.26 62.98 90.25
313 PRME / Prime Medicine, Inc. Mga National Commercial Banks 425.17 10.50 4.04 6.97 3.24 114.79 90.22
314 BORR / Borr Drilling Limited
Borr Drilling Limited, headquartered in Bermuda, operates in the energy sector, primarily focusing on providing drilling services for the oil and gas industry. Established in 2016, the company specializes in acquiring and operating modern jack-up rigs used for offshore drilling activities. Borr Drilling has swiftly grown its fleet to become one of the largest in its niche, supported by strategic acquisitions and investments in advanced drilling technologies. Its key projects predominantly involve collaborations with major oil companies, offering services that range from exploratory to developmental drilling. Leveraging a strategy of operating a young and highly efficient fleet, Borr Drilling aims to fulfill the increasing global demand for fossil fuels while maintaining stringent environmental and safety standards.
Drilling Oil and Gas Wells 687.41 2.91 124.79 90.21
315 NUVB / Nuvation Bio Inc. Mga Paghahanda sa Parmasyutiko 1,016.43 10.50 6.06 7.65 2.97 157.14 90.20
316 IOVA / Iovance Biotherapeutics, Inc.
Iovance Biotherapeutics, Inc., based in the United States, operates primarily within the biotechnology industry, focusing its efforts on pioneering novel cancer immunotherapies. The company is notably invested in the development of tumor-infiltrating lymphocyte (TIL) products for the treatment of patients with severe cancer conditions. Iovance's flagship projects include lifileucel for metastatic melanoma and LN-145 for cervical and head and neck cancers. These investigational therapies are designed to enhance the anti-tumor activity of patient-derived T cells by expanding and reinfusing them into the patient, a method that potentially offers a significant advancement in personalized cancer treatment. The company's dedication to transforming the treatment landscape for resistant or recurrent cancers positions it at the forefront of innovation within its field.
Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 760.77 21.00 1.01 9.28 2.23 317.17 90.20
320 LX / LexinFintech Holdings Ltd. - Depositary Receipt (Common Stock)
LexinFintech Holdings Ltd. is a leading fintech company based in China, primarily engaged in the provision of online consumer finance services. It operates through its proprietary technology platform, Fenqile, which specializes in offering personal installment loans, installment purchase loans, and other loan products to the educated young adults in China. LexinFintech utilizes advanced risk management technology to ensure credit quality and enhance user engagement. In addition to its core loan services, the company also runs Juzi Licai, an online investment platform, thus diversifying its revenue streams. Notably, LexinFintech's strategic focus remains on expanding its technological capabilities and exploring new financial services to foster sustainable growth amidst a dynamic fintech landscape.
Mga Serbisyo sa Pananalapi 1,077.65 14.91 4.85 11.76 6.32 85.84 90.16
324 EXOD / Exodus Movement, Inc. 726.92 68.25 45.45 56.04 25.22 123.25 90.15
325 LCTX / Lineage Cell Therapeutics, Inc.
Lineage Cell Therapeutics, Inc., headquartered in the United States, operates primarily within the biotechnology industry, focusing on the development of novel cell therapies. This company specializes in regenerative medicine, utilizing its proprietary cell-based therapy platform to advance a diverse project pipeline targeting conditions such as spinal cord injuries, dry age-related macular degeneration, and cancer. Key projects include OpRegen®, a retinal pigment epithelium transplant therapy for the treatment of AMD, and VAC2, a dendritic cell vaccine used in cancer immunotherapy. Lineage Cell Therapeutics is dedicated to innovation in the therapeutic use of pluripotent cells, aiming to improve patient outcomes by harnessing the potential of cell-based technologies.
Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 267.18 9.45 2.02 4.25 1.17 260.17 90.14
326 BCAX / Bicara Therapeutics Inc. 650.85 50.40 8.08 33.83 11.94 183.57 90.13
327 SLNO / Soleno Therapeutics, Inc.
Soleno Therapeutics, Inc. is a biopharmaceutical company based in the United States, specifically in Redwood City, California. It operates chiefly within the healthcare sector, focusing on the development and commercialization of novel therapeutics for the treatment of rare diseases. A key project for Soleno is its ongoing development of diazoxide choline controlled-release (DCCR) tablets, which are primarily aimed at treating Prader-Willi Syndrome, a complex genetic disorder characterized by insatiable hunger and severe obesity. The company's research and development efforts are geared towards addressing unmet medical needs in metabolic and neurological disorders, leveraging its proprietary platform to enhance the efficacy and safety of traditional therapeutics.
Mga Paghahanda sa Parmasyutiko 3,409.55 152.25 107.06 120.97 67.67 78.95 90.13
328 ONON / On Holding AG 14,720.40 92.60 50.11 67.54 45.08 49.82 90.11
329 VTGN / Vistagen Therapeutics, Inc. Mga Paghahanda sa Parmasyutiko 97.51 15.75 12.12 13.26 3.34 298.20 90.11
330 SG / Sweetgreen, Inc. Mga Restaurant, Kainan, at Lugar ng Kainan 1,075.60 26.25 10.10 15.76 9.10 73.32 90.09
331 MRVL / Marvell Technology, Inc.
Marvell Technology, Inc., headquartered in the United States, operates primarily in the semiconductor industry, providing a range of solutions pivotal to the infrastructure sector. The company focuses on the development and production of high-performance, complex semiconductor products and platforms which address the data processing, storage, networking, and connectivity requirements critical in high-growth markets like automotive, industrial, telecom, and enterprise computing. Key projects include advancements in 5G technology, data center servers, and automotive networking solutions. Marvell is recognized for pushing the boundaries of silicon design to support the massive data economy and the widespread adoption of cloud computing and 5G infrastructure, positioning itself strategically at the forefront of technological innovation in the semiconductor space.
Mga Semiconductor at Mga Kaugnay na Device 54,231.66 141.75 64.96 93.56 62.86 48.82 90.08
332 ENOV / Enovis Corporation
Enovis Corporation, based in the United States, operates primarily within the medical technology sector. The company focuses on developing, manufacturing, and distributing a wide range of innovative medical devices and solutions that cater to the orthopedics market. Enovis is noted for its forward-looking approach to healthcare, with significant investments in motion-preserving technologies, digital solutions for surgical outcomes, and personalized medicine through advanced robotics and sensor-based technologies. Its key projects typically revolve around the enhancement of patient care in orthopedic procedures and rehabilitation, underscoring its commitment to improving clinical outcomes through technology-driven products and therapies.
Mga Orthopedic, Prosthetic, at Surgical Appliances at Supplies 1,766.23 78.75 41.41 55.42 30.90 79.27 90.06
333 MGTX / MeiraGTx Holdings plc Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 587.26 52.50 12.12 27.88 7.30 281.92 90.04
344 PRCT / PROCEPT BioRobotics Corporation Mga Instrumento at Apparatus ng Surgical at Medikal 2,229.44 89.25 51.51 68.44 40.17 70.21 89.91
345 BDTX / Black Diamond Therapeutics, Inc. Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 155.87 11.55 9.09 10.46 2.75 281.57 89.90
346 NOTE / FiscalNote Holdings, Inc.
FiscalNote Holdings, Inc., based in the United States, operates primarily within the legal technology sector, providing a platform that offers real-time legal and regulatory data, aiming to transform how global organizations manage risk and compliance issues. The company has developed a suite of software services, which includes tools for monitoring legislative and regulatory developments, stakeholder management, and issues management, designed to enhance the decision-making capabilities of corporate and governmental agencies by harnessing artificial intelligence and machine learning technologies. FiscalNote’s offerings support various entities in navigating complex, dynamically changing policymaking environments efficiently, illustrating its commitment to integrating cutting-edge technology with legal and regulatory solutions.
Mga Serbisyo sa Negosyo, Hindi Nauuri sa Ibang Lugar 69.39 4.72 1.52 2.91 0.42 583.36 89.89
350 VTEX / VTEX
VTEX, based in Brazil, operates within the software as a service (SaaS) industry, specializing in enabling digital commerce transformations for major retailers and brands across global markets. Its platform integrates online sales, marketplace, and order management functionalities to create a comprehensive cloud-based ecosystem for e-commerce operations. A key project in VTEX's portfolio includes the omni-channel solutions that unify online and offline sales channels, enhancing customer experiences while optimizing operational workflows. These solutions leverage advanced data analysis, inventory management, and customer service technologies, establishing VTEX as a pivotal player in facilitating digital commerce scalability and innovation for enterprises looking to expand their reach in the digital economy.
Naka-prepack na Software 742.41 12.60 7.37 9.30 4.08 127.30 89.87
352 VNET / VNET Group, Inc. - Depositary Receipt (Common Stock) Computer Programming, Pagproseso ng Data, At Iba Pang Serbisyong Kaugnay ng Computer 2,329.83 25.44 10.10 13.87 8.66 59.78 89.86
355 CTNM / Contineum Therapeutics, Inc. 270.34 30.45 16.16 23.26 10.45 122.97 89.83
356 KYMR / Kymera Therapeutics, Inc. Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 2,907.32 73.50 53.53 61.37 41.20 48.94 89.83
357 WIX / Wix.com Ltd.
Wix.com Ltd., based in Israel, operates within the technology sector, specializing primarily in cloud-based web development services. The company offers solutions that simplify website creation and business management for individuals and small to medium-sized enterprises. Wix.com enables users to design customizable websites using drag-and-drop tools and offers a variety of web templates and applications. Additionally, Wix supports businesses with specific solutions including e-commerce, music, online booking, and integrated CRM services. In pursuing its mission to democratize web development, Wix continuously enhances its platform by introducing AI-driven tools and advanced editor features, ensuring users can maintain cutting-edge and functional websites with minimal technical skills.
Computer Programming, Pagproseso ng Data, At Iba Pang Serbisyong Kaugnay ng Computer 7,887.14 267.75 161.60 212.27 141.08 50.46 89.82
358 FHTX / Foghorn Therapeutics Inc. Mga Paghahanda sa Parmasyutiko 282.36 14.70 9.09 11.90 5.06 135.18 89.81
360 TENX / Tenax Therapeutics, Inc. Mga Paghahanda sa Parmasyutiko 235.48 31.50 14.14 21.76 5.95 263.27 89.79
362 LNTH / Lantheus Holdings, Inc.
Lantheus Holdings, Inc., based in the United States, is a prominent player in the healthcare sector, specializing in diagnostic imaging and targeted radiotherapeutics. The company develops, manufactures, and commercializes essential radiopharmaceutical agents and products pivotal for diagnostic imaging procedures and disease treatment. Key products include PyL (piflufolastat F 18) used for prostate cancer imaging, and DEFINITY, an ultrasound enhancing agent for use in patients with suboptimal echocardiograms. Lantheus is continuously advancing in the field of precision diagnostics and therapeutics with a strong focus on developing innovative products that improve clinical outcomes and contribute to significant advancements in medical imaging and oncology. The company's strategic initiatives are heavily geared towards expanding its pipeline in radiopharmaceuticals to address various critical healthcare needs.
Mga In Vitro at In Vivo Diagnostic Substances 3,731.13 136.50 63.63 91.96 54.90 67.56 89.78
365 HUBS / HubSpot, Inc.
HubSpot, Inc., headquartered in the United States, operates primarily within the technology sector, focusing on cloud-based marketing, sales, and customer service software and services. The company's core product suite includes tools aimed at social media marketing, content management, web analytics, and search engine optimization, designed to assist businesses in attracting visitors, converting leads, and achieving customer loyalty. HubSpot's commitment to 'inbound marketing' strategies has distinguished it within the tech industry, as it helps customers draw in clients through personalized, content-driven engagement. Key projects for HubSpot involve continuous enhancement of its CRM platform, advancing artificial intelligence capabilities within marketing automation, and expanding its services to offer a comprehensive ecosystem for customer relationship management, directly addressing the evolving needs of global businesses in maintaining competitive digital presence and operational efficiency.
Naka-prepack na Software 25,463.54 955.50 598.93 710.46 483.17 47.04 89.75
366 MNDY / monday.com Ltd.
Monday.com Ltd. is an Israeli software company primarily engaged in the development of a cloud-based platform that facilitates team management and project management. Based in Tel Aviv, Israel, its platform serves various business functions including marketing, sales, IT, and operations, integrating multiple tools into a cohesive workflow. The platform is distinguished by features that support the centralization of project tracking, communication, and time management, making it adaptable for both small businesses and large enterprises. Key projects revolve around continuous enhancements to their work operating system (Work OS), which enables organizations to build custom workflow apps for any aspect of their operations. This focus on customization and scalability has been instrumental in its global reach and adoption across diverse industries.
Naka-prepack na Software 9,957.16 472.50 217.15 288.16 193.00 49.19 89.75
367 TEAM / Atlassian Corporation
Atlassian Corporation, based in Australia, is a prominent player in the software industry, specifically in the domain of team collaboration and productivity software. The company is renowned for its suite of products that enhance project management, code development, and issue tracking. Key offerings include Jira, used primarily for bug tracking and project management; Confluence, a team collaboration platform; and Trello, a project management application using the Kanban methodology. Atlassian serves a diverse global clientele ranging from small businesses to large enterprises, constantly evolving its solutions to meet the dynamic needs of developers and project teams in a rapidly advancing technological landscape.
Naka-prepack na Software 46,706.60 441.00 197.96 263.50 177.78 48.31 89.73
372 PMVP / PMV Pharmaceuticals, Inc. Mga Paghahanda sa Parmasyutiko 74.72 18.90 6.06 10.20 1.40 623.40 89.68
376 WRN / Western Copper and Gold Corporation Pagmimina ng Metal 286.79 4.12 1.87 2.86 1.41 99.93 89.63
377 ABCL / AbCellera Biologics Inc.
AbCellera Biologics Inc., based in Canada, operates within the biotechnology industry, focusing prominently on the discovery of therapeutic antibodies. The company leverages a proprietary technology platform that integrates artificial intelligence, genomics, and microfluidics to streamline the antibody discovery process for its partners, which include notable pharmaceutical and biotech firms. A key project that exemplifies AbCellera's capabilities is its collaboration on the development of a successful COVID-19 monoclonal antibody treatment with Eli Lilly, highlighting its strength in rapidly responding to global health challenges. AbCellera's innovative approach aims to enhance the speed and efficacy of developing antibody therapies, positioning it as a leader in the biotech sector.
Mga Paghahanda sa Parmasyutiko 1,231.83 17.85 5.05 9.47 4.18 127.40 89.62
378 SABS / SAB Biotherapeutics, Inc. Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 19.33 14.70 5.05 9.38 2.06 351.15 89.62
382 AIOT / PowerFleet, Inc.
PowerFleet, Inc., headquartered in the United States, operates primarily in the industrial Internet of Things (IoT) sector. The company specializes in providing wireless IoT solutions for securing, controlling, tracking, and managing high-value enterprise assets such as industrial trucks, trailers, containers, cargo, and vehicles. PowerFleet's robust suite of offerings includes telematics technology, which combines telecommunications and informatics, to greatly enhance fleet management, improve safety, and increase operational efficiency. Serving a diverse clientele spread across logistics, transportation, and supply chain sectors, PowerFleet has implemented key projects that include advanced asset management and resource optimization solutions. This combination of technology and service facilitates substantial enhancements in asset utilization and workforce productivity for businesses worldwide.
Communications Equipment, Not Elsewhere Classified 618.22 15.75 8.08 10.54 4.67 125.70 89.59
386 ROIV / Roivant Sciences Ltd.
Roivant Sciences Ltd., based in Switzerland and the United States, is a biopharmaceutical company primarily engaged in the development of innovative medicines through its unique technology-driven platform, which expedites the drug development process. Concentrating on a broad spectrum of disease areas, Roivant Sciences employs a strategic approach to build 'Vants'—nimble, entrepreneurial biotech and healthcare technology units—dedicated to pioneering advancements in medical research and patient care. This corporate structure allows for enhanced focus and agility in progressing therapeutic products and technologies across diverse fields such as neurology, dermatology, and hepatology. Roivant's key projects often target underserved medical needs, offering potential new therapies that could significantly alter treatment paradigms, highlighting its commitment to disruptive innovation in the healthcare sector.
Mga Paghahanda sa Parmasyutiko 8,145.82 42.00 12.12 19.89 11.93 66.58 89.51
390 GERN / Geron Corporation
Geron Corporation, based in the United States, operates within the biotechnology industry, focusing predominantly on the development of therapeutic products for oncology. A central aspect of its research and product development is the telomerase inhibitor drug, imetelstat. This investigational compound is designed to selectively target and inhibit the enzymatic activity of telomerase, a critical enzyme in cancer cells implicated in cellular aging and tumor growth. Geron's key projects include clinical trials assessing the efficacy of imetelstat in treating hematologic myeloid malignancies, particularly myelofibrosis and myelodysplastic syndromes. These studies aim to address significant unmet medical needs and enhance survival rates of patients with these severe diseases, potentially offering groundbreaking treatments in oncology.
Mga Paghahanda sa Parmasyutiko 896.18 6.30 1.01 3.70 1.40 163.17 89.48
391 PEPG / PepGen Inc. Mga Paghahanda sa Parmasyutiko 38.54 10.50 1.01 7.14 1.16 507.66 89.48
392 HUMA / Humacyte, Inc. Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 243.11 26.25 3.03 9.44 1.55 506.75 89.46
393 COYA / Coya Therapeutics, Inc. Mga Paghahanda sa Parmasyutiko 110.05 21.00 14.14 16.98 6.56 157.99 89.45
395 KELYB / Kelly Services, Inc.
Kelly Services, Inc., headquartered in the United States, operates as a global workforce solutions provider specializing in the staffing sector. The firm caters to a broad spectrum of industries, including administrative, industrial, technology, and more. Kelly Services is known for pioneering temporary staffing services in the U.S., evolving into a comprehensive provider of both temporary and permanent placement. Key initiatives have broadened to include outsourcing and consulting services tailored to enhance operational efficiency and workforce flexibility for their clients. The company places significant emphasis on evolving workforce demands, utilizing technology to develop innovative staffing and workforce management solutions, thus aligning with shifts in the global labor market.
Help Supply Services 500.87 29.70 26.45 27.78 14.00 98.45 89.42
396 TLSI / TriSalus Life Sciences, Inc. Mga Instrumento at Apparatus ng Surgical at Medikal 198.84 16.80 9.09 11.54 5.22 120.42 89.41
398 RGEN / Repligen Corporation
Repligen Corporation, based in the United States, operates primarily in the bioprocessing industry where it develops and manufactures products that are integral to the production of biological drugs. The company focuses on producing high-performance chromatography products, filtration systems, and protein products essential for biomanufacturing processes. Repligen has notably expanded its portfolio through strategic acquisitions which enhance its offerings in the advanced filtration and chromatography space, responding to the increasing demands of the biopharmaceutical market. Its key projects often revolve around innovations in filtration devices and bioprocessing equipment, aiming to optimize the efficiency and cost-effectiveness of drug manufacturing and meet stringent regulatory standards globally, further reinforcing its position as a leader in the bioprocessing sector.
Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 6,876.34 231.00 131.30 183.61 122.32 50.16 89.39
399 AXSM / Axsome Therapeutics, Inc.
Axsome Therapeutics, Inc., based in the United States, operates within the pharmaceutical industry, focusing predominantly on the development of novel therapies for central nervous system (CNS) disorders. Key projects include AXS-05, which is under development for multiple CNS conditions including major depressive disorder and Alzheimer’s disease agitation. The company also advances AXS-07, designed for the acute treatment of migraine, and AXS-12, aimed at managing symptoms of narcolepsy. Through a combination of unique molecular approaches and clinical strategies, Axsome seeks to address complex medical needs effectively, enhancing therapeutic benefits and treatment accessibility for patients suffering from serious neurological conditions.
Mga Paghahanda sa Parmasyutiko 6,041.10 210.00 145.44 179.18 121.28 47.75 89.38
400 FATE / Fate Therapeutics, Inc.
Fate Therapeutics, Inc., based in the United States, operates primarily within the biopharmaceutical sector, focusing on the development of programmed cellular immunotherapies for cancer and immune disorders. The company’s technology is built on harnessing the biological prowess of immune cells, including natural killer (NK) cells and T cells, among others, from induced pluripotent stem cells (iPSCs). This innovative approach enables the mass production of off-the-shelf, multipotent cell-based treatments. Fate Therapeutics is actively advancing a diverse pipeline of cellular immunotherapies, leading projects that include several in clinical trials aiming to address both hematologic malignancies and solid tumors. The company has established strategic collaborations with major entities to enhance resource sharing and development capabilities in its cutting-edge research areas.
Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 119.81 12.60 2.02 5.05 1.04 383.16 89.38
401 CZR / Caesars Entertainment, Inc.
Caesars Entertainment, Inc., based in the United States, is a prominent figure in the global gaming and hospitality industry. The company operates an extensive network of casinos, hotels, and entertainment venues, offering gaming, dining, and live performance services across significant markets. Key projects include integrating advanced technology for enhanced customer experiences and expanding its digital sports betting and online gaming operations. Recent strategic ventures involve the renovation and rebranding of properties to attract a broad demographic while maintaining high-end offerings for premium clients. These endeavors underscore Caesars' commitment to maintaining its competitive edge in a dynamic industry, continuously innovating while providing high-quality leisure and entertainment services.
Mga Hotel at Motel 5,568.16 63.36 27.27 43.16 26.77 61.23 89.37
405 AARD / Aardvark Therapeutics, Inc. 179.43 52.50 19.19 33.46 8.30 304.55 89.30
406 CPRX / Catalyst Pharmaceuticals, Inc.
Catalyst Pharmaceuticals, Inc., based in Coral Gables, Florida, United States, operates primarily in the biopharmaceutical industry, specializing in the development and commercialization of innovative therapies for people with rare debilitating, chronic neuromuscular, and neurological diseases. Established in 2002, its key product, Firdapse, is approved for the treatment of adults with Lambert-Eaton myasthenic syndrome (LEMS), a rare autoimmune disorder. Catalyst has also been expanding its product line to include treatments for other medical conditions such as congenital myasthenic syndromes and myasthenia gravis. The company's focus remains on addressing unmet medical needs by targeting complex challenges within the neuromuscular sector, demonstrating a consistent commitment to innovation and patient care in specialized medicine.
Mga Paghahanda sa Parmasyutiko 2,519.92 42.00 31.31 34.68 20.59 68.43 89.29
407 ISOU / IsoEnergy Ltd.
IsoEnergy Ltd. is a Canadian-based uranium exploration and development company, primarily engaged in the discovery and evaluation of uranium deposits within the Eastern Athabasca Basin in Saskatchewan, Canada. One of their key projects includes the Hurricane Zone at the Larocque East property, where significant high-grade uranium mineralization has been identified. The company actively explores this region, leveraging advanced geophysical and geochemical techniques to delineate and expand its uranium resources, aiming to contribute to the growing demand for raw materials used in nuclear energy production. IsoEnergy is strategically positioned with its uranium exploration projects to capitalize on the increasing global emphasis on clean and sustainable energy sources.
430.63 21.99 12.57 15.92 8.08 97.00 89.29
409 NUVL / Nuvalent, Inc. Mga Paghahanda sa Parmasyutiko 5,517.81 147.00 101.00 117.76 76.58 53.70 89.25
413 ALT / Altimmune, Inc.
Altimmune, Inc., based in the United States, operates within the biotechnology industry, focusing on the development of immunotherapeutics and vaccines. The company is notably active in advancing novel treatments for respiratory diseases, liver diseases, and obesity. One of its key products under development, NasoShield, is an intranasal anthrax vaccine designed to induce immune responses with a single dose. Additionally, Altimmune is working on AdCOVID, a single-dose intranasal vaccine candidate for COVID-19, which aims to stimulate a broad immune response including both systemic immunity and local immunity in the nasal cavity. These endeavors underscore the company's commitment to innovative approaches in addressing significant health challenges.
Mga Paghahanda sa Parmasyutiko 324.57 29.40 1.01 18.81 3.83 393.14 89.20
415 TNDM / Tandem Diabetes Care, Inc.
Tandem Diabetes Care, Inc., based in the United States, operates primarily within the healthcare sector, specializing in the design, development, and commercialization of products for people with insulin-dependent diabetes. The company's innovative portfolio focuses primarily on insulin pump technology and includes the t:slim X2 insulin pump, which is notable for its user-friendly touch screen interface. Tandem Diabetes Care is also committed to advancing diabetes management technology through continuous development of their integrated diabetes management solutions. These efforts include the integration of their pumps with continuous glucose monitoring systems to enhance therapy effectiveness and user convenience, thereby supporting better glycemic control for its users. This focus on high-tech, user-centric design keeps Tandem at the forefront of the medical device industry in diabetes care.
Mga Instrumento at Apparatus ng Surgical at Medikal 844.81 53.55 10.45 22.75 12.51 81.55 89.16
417 OS / OneStream, Inc. 3,876.89 39.90 25.25 30.34 20.79 45.75 89.14
421 PHAT / Phathom Pharmaceuticals, Inc. Mga Paghahanda sa Parmasyutiko 853.87 30.45 12.12 21.80 12.18 79.08 89.12
422 AKBA / Akebia Therapeutics, Inc.
Akebia Therapeutics, Inc., based in the United States, operates within the biopharmaceutical industry and focuses primarily on developing and commercializing therapeutics for patients with kidney disease. Established with a mission to improve the lives of people affected by these conditions, Akebia has been notably involved in the development of innovative treatments that address complications related to kidney disease. One of its key products includes Auryxia® (ferric citrate), which is approved for the control of serum phosphorus levels in patients with chronic kidney disease on dialysis and for treating iron deficiency anemia in adult patients with chronic kidney disease not on dialysis. The company’s strategic initiatives are geared towards advancing a pipeline that addresses the significant unmet medical needs in nephrology.
Mga Paghahanda sa Parmasyutiko 1,665.11 10.50 6.06 7.55 3.14 140.00 89.10
425 QNCX / Quince Therapeutics, Inc. Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 84.73 10.50 4.04 7.65 1.60 384.18 89.07
428 PHVS / Pharvaris N.V.
Pharvaris N.V., based in the Netherlands, is a biopharmaceutical company primarily engaged in the discovery and development of novel oral therapies for the treatment of hereditary angioedema (HAE) and other related conditions. The company focuses on creating small-molecule alternatives to injected therapies for HAE, a rare genetic disorder characterized by recurring swelling attacks. A key project includes the development of PHA121, an oral bradykinin B2 receptor antagonist, designed to provide a rapid, reliable, and durable response in the acute treatment of HAE symptoms. By innovating oral treatment options, Pharvaris aims to improve accessibility and quality of life for patients suffering from this debilitating condition.
Mga Paghahanda sa Parmasyutiko 1,175.20 54.60 14.14 33.94 21.65 58.07 89.06
430 LUCD / Lucid Diagnostics Inc. Mga Instrumento at Apparatus ng Surgical at Medikal 128.81 8.14 2.02 3.70 1.26 192.29 89.04
431 GBIO / Generation Bio Co. Mga Paghahanda sa Parmasyutiko 40.54 73.50 10.10 27.28 6.00 353.24 89.00
432 SGML / Sigma Lithium Corporation
Sigma Lithium Corporation is a Canada-based company primarily engaged in the exploration and development of lithium deposits. Operating within the materials sector, the company focuses on supplying lithium for electric vehicle batteries and other high-growth markets. Sigma Lithiform’s key project is the Grota do Cirilo lithium project, located in Brazil, which is noteworthy as one of the largest hard rock lithium spodumene deposits in the Americas. This project has gained attention for its environmentally sustainable approach to mining and production, incorporating proprietary greentech methodologies and aiming to generate minimal waste with a low environmental footprint. Sigma Lithium endeavors to become a major supplier in the global lithium market by leveraging its high-grade lithium deposits and sustainable mining practices.
747.26 14.36 11.90 12.99 6.71 93.42 88.98
434 NPCE / NeuroPace, Inc. Mga Instrumento at Apparatus ng Surgical at Medikal 302.03 21.00 13.13 17.19 9.15 88.12 88.97
436 JAZZ / Jazz Pharmaceuticals plc
Jazz Pharmaceuticals plc is a biopharmaceutical company headquartered in Dublin, Ireland. The company specializes in developing and commercializing pharmaceutical products aimed at addressing unmet medical needs, particularly in the fields of neuroscience and oncology. Key areas of focus include sleep disorders and hematologic malignancies. A notable project is the development and commercialization of Xywav, an oxybate medication approved for conditions such as narcolepsy. Jazz Pharmaceuticals pursues both organic growth through drug development and strategic acquisitions to enhance its product portfolio and expand its market reach globally. This integrated approach helps the company maintain a leading position in its specialized therapeutic areas.
Mga Paghahanda sa Parmasyutiko 7,819.98 241.50 146.45 187.39 127.75 46.64 88.95
438 LFMD / LifeMD, Inc. Offices and Clinics of Doctors of Medicine 278.34 18.90 8.08 12.82 6.19 107.49 88.94
441 PTLO / Portillo's Inc. Mga Restaurant, Kainan, at Lugar ng Kainan 509.34 18.90 8.08 12.14 7.08 71.32 88.91
442 FUN / Six Flags Entertainment Corporation Sari-saring Libangan At Libangan 2,297.45 63.00 23.23 36.88 22.69 62.52 88.90
446 PROP / Prairie Operating Co. Industrial Organic Chemicals 116.56 22.84 3.03 10.39 2.55 306.70 88.87
448 ECOR / electroCore, Inc. Electromedical at Electrotherapeutic Apparatus 39.65 26.25 12.12 21.50 5.31 304.93 88.85
450 BITF / Bitfarms Ltd.
Bitfarms Ltd. is a publicly traded cryptocurrency mining company primarily involved in the production of Bitcoin. Based in Toronto, Canada, the company constitutes a significant presence in the blockchain sector by operating one of the largest cryptocurrency mining operations in North America. Bitfarms' key projects focus on expanding its mining capabilities and enhancing energy efficiency across its data centers that are strategically located to utilize cost-effective, predominantly hydroelectric power. This commitment not only to scale but also to sustainability, seeks to position Bitfarms favorably within an increasingly competitive and environmentally concerned market. The firm continually invests in the latest mining technology and infrastructure to ensure high operational efficiency and profitability in the volatile cryptocurrency landscape.
Mga Serbisyo sa Pananalapi 741.54 3.76 1.45 2.56 1.34 92.17 88.84
451 FLOC / Flowco Holdings Inc. 419.65 31.50 26.26 28.39 16.32 74.06 88.83
452 DCTH / Delcath Systems, Inc.
Delcath Systems, Inc., based in the United States, operates within the healthcare industry, focusing primarily on specialty pharmaceuticals and medical devices. The company is renowned for its development of percutaneous hepatic perfusion (PHP) technology, a targeted therapy for the treatment of primary and metastatic liver cancers. Delcath's flagship product, the CHEMOSAT/Melphalan HDS system, is designed to administer high-dose chemotherapy directly to the liver while controlling systemic exposure and reducing side effects. This innovative approach aims to improve cancer control and patient outcomes, positioning Delcath Systems at the forefront of interventional oncology. The company holds significant ambitions to expand the therapeutic applications of its PHP technology into other areas of unmet medical need in oncology.
Mga Instrumento at Apparatus ng Surgical at Medikal 385.21 32.55 21.21 25.21 11.02 128.75 88.82
462 TWST / Twist Bioscience Corporation Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 1,622.89 60.03 35.35 45.58 26.97 69.06 88.73
463 CRIS / Curis, Inc.
Curis, Inc. is a biotechnology company based in the United States, with a primary focus on developing innovative therapeutics for the treatment of cancer. The company is actively engaged in the research and development of next-generation targeted oncology drugs that seek to modulate pathways directly involved in cancer progression and immune system regulation. Key to its portfolio is the advancement of small molecule drug candidates. Curis is notable for its collaboration with larger pharmaceutical entities, which helps accelerate the development and potential commercialization of its therapies. Among its prominent projects are inhibitors targeting the PI3K and HDAC pathways, pivotal in both tumor growth and immune response modulation. These projects underscore the company's commitment to addressing unmet medical needs in oncology through molecular insights and targeted therapy development.
Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 17.87 21.00 12.12 16.66 1.67 891.66 88.73
464 RNA / Avidity Biosciences, Inc. Mga Paghahanda sa Parmasyutiko 5,622.22 100.80 50.50 68.64 46.58 47.45 88.73
466 CDXS / Codexis, Inc.
Codexis, Inc., based in the United States, operates primarily within the biotechnology sector focusing on the development of novel enzymes that enhance the efficiency of pharmaceutical manufacturing processes and enable the generation of biotherapeutic products. A leading element of their project portfolio includes customizing enzymes for use in the production of small molecule pharmaceuticals and DNA/RNA synthesis, sectors marked by rigorous patent adherence and rapid technological advancements. Additionally, Codexis is notable for its Protein Engineering Platform, which is leveraged not only to generate biotherapeutics but also to drive innovation in industrial biocatalysis. Their strategic approach encapsulates partnerships with pharmaceutical entities, employing a model that underscores the transformative impact of enzymatic applications in bioprocessing and therapeutic development.
Industrial Organic Chemicals 246.84 11.55 3.03 7.22 2.73 164.17 88.72
467 CMG / Chipotle Mexican Grill, Inc.
Chipotle Mexican Grill, Inc., based in the United States, operates as a leader in the fast-casual dining sector, primarily focusing on Mexican-inspired foods such as burritos, tacos, and bowls. The company champions a business model that emphasizes fresh ingredients, sustainable sourcing, and transparent food preparation methods. A notable aspect of its operational strategy includes a significant commitment to digital innovation and expansion, enabling efficient online ordering, pick-up, and delivery services, which have been crucial amid changing dining behaviors during and post-pandemic periods. Chipotle continues to prioritize sustainability and ethical sourcing, aiming to make an impact on both the environment and local communities by supporting small to medium-sized farmers.
Mga Restaurant, Kainan, at Lugar ng Kainan 56,527.65 76.65 46.46 60.41 42.14 43.37 88.72
474 CLNN / Clene Inc.
Clene Inc. is a biopharmaceutical company based in the United States, primarily focused on the innovation of unique therapies for neurodegenerative diseases. The company is pioneering in the development of nanotherapeutics designed to enhance cellular energetics. One of their key projects includes CNM-Au8, an investigational nanocatalyst aimed at improving the cellular bioenergetic processes critical for repairing and maintaining cellular health. The company’s approach involves a proprietary clean-surfaced nanotechnology platform that is being tested in various clinical trials for conditions such as multiple sclerosis, Parkinson’s disease, and amyotrophic lateral sclerosis. With its uniquely positioned technology, Clene Inc. is committed to addressing complex neurodegenerative disorders by improving fundamental cellular functions.
Mga Paghahanda sa Parmasyutiko 50.34 50.40 20.20 31.33 5.32 488.88 88.63
475 TVRD / Tvardi Therapeutics, Inc. 277.83 81.90 42.42 58.29 29.92 96.65 88.63
477 XFOR / X4 Pharmaceuticals, Inc. 29.89 31.50 3.54 13.16 3.76 250.41 88.61
478 ZNTL / Zentalis Pharmaceuticals, Inc. Mga Paghahanda sa Parmasyutiko 122.27 10.50 2.52 6.31 1.69 272.35 88.61
480 COGT / Cogent Biosciences, Inc. Mga Paghahanda sa Parmasyutiko 1,377.15 29.40 11.11 19.48 12.08 61.27 88.60
483 MBX / MBX Biosciences, Inc. 505.40 46.20 30.30 38.47 15.09 155.69 88.60
484 VSTM / Verastem, Inc. Mga Paghahanda sa Parmasyutiko 569.09 21.00 13.13 15.43 9.25 66.96 88.60
486 CLNE / Clean Energy Fuels Corp.
Clean Energy Fuels Corp., based in the United States, operates within the alternative energy sector, focusing primarily on natural gas as a cleaner alternative to conventional fuels for transportation. The company specializes in building infrastructure to supply liquefied and compressed natural gas (LNG and CNG), thereby supporting environmental sustainability by reducing greenhouse gas emissions. Key projects include partnerships with major transportation agencies and companies to convert fleets to natural gas, and the development of "Redeem," a renewable natural gas product sourced from biogenic methane produced by landfill waste. The firm's strategic initiatives have positioned it as a leader in the North American market for natural gas fuel and related services for commercial, industrial, and public sector transportation.
Pinagsamang Gas at Iba Pang Serbisyo 577.56 10.50 2.22 4.58 2.63 73.98 88.59
489 KVYO / Klaviyo, Inc. Naka-prepack na Software 9,720.17 63.00 37.37 47.17 32.44 45.50 88.51
490 BCAB / BioAtla, Inc. Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 26.77 10.50 10.10 10.20 0.46 2,137.82 88.49
493 ASUR / Asure Software, Inc. Computer Integrated Systems Design 229.87 15.75 11.11 13.41 8.40 59.96 88.47
497 NRXP / NRx Pharmaceuticals, Inc.
NRx Pharmaceuticals, Inc., headquartered in the United States, operates prominently within the pharmaceutical industry. The company is dedicated to pioneering novel therapies, focusing on mental health disorders and inflammatory diseases. A pivotal project undertaken by NRx Pharmaceuticals is the development of Cyclurad, a treatment designed for suicidal bipolar depression, which is an innovation underpinned by intellectual property and strategic collaborations with academic and medical institutions. Another significant initiative focuses on addressing critical care therapies for lung injury and cytokine storm syndrome related to COVID-19, demonstrating the company's commitment to responding to urgent global health crises. NRx Pharmaceuticals continues to evolve its research and clinical trials to meet complex healthcare challenges, leveraging cutting-edge science and strategic partnerships.
Mga Paghahanda sa Parmasyutiko 45.37 48.30 19.19 29.84 2.32 1,180.47 88.45
503 ARAY / Accuray Incorporated
Accuray Incorporated, based in the United States, operates primarily in the medical technology industry, specializing in the development, manufacturing, and selling of radiation therapy systems. The company's notable contributions include the CyberKnife and TomoTherapy systems, which are designed to deliver precise radiotherapy and radiosurgery treatments for cancerous and non-cancerous tumors, as well as other specified medical conditions. Accuray's innovative solutions focus on improving the accuracy and efficiency of radiation therapy, aiming to maximize patient outcomes while minimizing side effects associated with treatment. The firm's commitment to continuous innovation and global expansion has established its reputation in the precision radiation oncology field, addressing critical needs in cancer treatment worldwide.
Mga Instrumento at Apparatus ng Surgical at Medikal 162.72 7.35 4.54 5.61 1.52 267.87 88.43
506 ALGS / Aligos Therapeutics, Inc.
Aligos Therapeutics, Inc., based in the United States, operates within the biotechnology industry, focusing specifically on developing innovative therapeutics for viral and liver diseases. The company is prominently engaged in the development of drugs targeting hepatitis B, NASH (nonalcoholic steatohepatitis), and coronaviruses. Their pipeline includes advanced oligonucleotide and small molecule modalities, aimed at leveraging distinct mechanisms to manage and potentially cure these conditions. Aligos' approach involves rigorous clinical trials and a dedication to scientific innovation to meet significant unmet medical needs in the hepatology and infectious disease sectors. Their commitment to addressing the complexities of these diseases reflects a blend of extensive research and strategic clinical development.
Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 63.91 183.75 36.36 81.86 10.55 687.82 88.41
510 VIR / Vir Biotechnology, Inc. Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 687.49 32.55 12.12 17.98 4.94 263.18 88.39
515 MLTX / MoonLake Immunotherapeutics Mga Paghahanda sa Parmasyutiko 3,540.59 113.40 61.61 80.26 55.75 43.89 88.37
516 GSRT / GSR III Acquisition Corp. 302.52 19.95 19.19 19.38 10.37 86.89 88.37
517 GOVX / GeoVax Labs, Inc. Mga Paghahanda sa Parmasyutiko 11.89 14.70 8.08 10.10 0.75 1,252.71 88.36
519 TNGX / Tango Therapeutics, Inc. Mga Paghahanda sa Parmasyutiko 743.95 13.65 8.08 11.07 6.71 65.04 88.35
522 CRGY / Crescent Energy Company Crude Petroleum at Natural Gas 2,429.03 21.00 10.10 14.71 9.54 54.14 88.33
523 VYNE / VYNE Therapeutics Inc. Mga Paghahanda sa Parmasyutiko 6.31 6.30 2.02 4.25 0.32 1,232.72 88.33
525 FRSH / Freshworks Inc.
Freshworks Inc., headquartered in San Mateo, California, USA, operates primarily in the software industry, focusing on developing intuitive and easy-to-use customer engagement, customer support, and IT service management applications. Established in Chennai, India in 2010, and later moving its headquarters to the United States, Freshworks provides a suite of products including Freshdesk, Freshservice, and Freshsales that integrate various business processes to enhance customer interaction and business efficiency. The company caters to a diverse range of businesses from startups to large enterprises, offering them scalable customer relationship management (CRM) solutions. Key initiatives involve leveraging artificial intelligence and machine learning to power their software solutions, thereby enhancing automation and the overall user experience.
Naka-prepack na Software 3,930.89 28.35 18.18 21.05 13.47 56.36 88.32
526 OTLK / Outlook Therapeutics, Inc.
Outlook Therapeutics, Inc., based in the United States, operates in the biopharmaceutical industry focusing on the development of complex monoclonal antibodies for various ophthalmic indications. The company's flagship project involves ONS-5010, commercially known as LYTENAVA™ (bevacizumab-vikg), which is an investigational ophthalmic formulation of bevacizumab currently undergoing clinical trials intended to secure FDA approval for the treatment of wet age-related macular degeneration. This project represents a significant advancement in therapeutic options for ocular diseases, aligning with the industry's move towards more targeted and efficacious treatment regimes. The strategic focus on innovative ophthalmic treatments positions Outlook Therapeutics as a niche player in the competitive biopharmaceutical landscape, underscoring its commitment to addressing critical unmet medical needs in the sector.
Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 37.11 22.05 3.03 8.84 0.85 935.74 88.31
529 AR / Antero Resources Corporation
Antero Resources Corporation, based in the United States, operates primarily in the oil and natural gas sector, focusing on the exploitation, development, and acquisition of natural gas, natural gas liquids, and oil properties. The company's activities are concentrated in the Appalachian Basin, which is rich in natural resources. Key projects involve both the Marcellus Shale and the Utica Shale, where Antero Resources has established itself as a significant player through strategic reserve acquisitions and the development of advanced extraction technologies. Their operations effectively combine horizontal drilling and hydraulic fracturing, enhancing resource recovery and operational efficiency, which positions them competitively within the energy market.
Crude Petroleum at Natural Gas 9,891.02 60.90 32.32 46.01 31.92 44.11 88.28
531 XENE / Xenon Pharmaceuticals Inc. Mga Paghahanda sa Parmasyutiko 2,978.34 68.25 43.43 55.35 38.71 42.99 88.27
545 KPTI / Karyopharm Therapeutics Inc.
Karyopharm Therapeutics Inc. is a biopharmaceutical company based in the United States, specifically headquartered in Newton, Massachusetts. It operates primarily in the pharmaceuticals industry, focusing on the discovery, development, and commercialization of novel therapies for the treatment of cancer and other major diseases. Key among its projects is the development of Selinexor, a first-in-class, oral Selective Inhibitor of Nuclear Export (SINE) compound, which has shown potential in treating multiple cancer types. The company has successfully advanced this compound through various clinical trials, leading to its FDA approval for specific oncological applications. Karyopharm continues to expand its research on SINE technology to explore therapeutic potentials across a diverse range of diseases.
Mga Paghahanda sa Parmasyutiko 62.00 31.50 8.08 17.95 7.11 150.38 88.16
555 ADBE / Adobe Inc.
Adobe Inc. is a prominent software company based in the United States, primarily involved in the creation of multimedia and creativity software products. Renowned for its Photoshop, Acrobat Reader, and Adobe Creative Cloud services, Adobe leads in the digital media and digital marketing sectors. The company's innovative solutions extend to digital experience management through Adobe Experience Cloud, which offers tools for analytics, advertising, and marketing. Adobe's constant emphasis on research and development helps maintain its competitive edge in the graphic design, video editing, web development, and digital marketing industries. Adobe continues to expand its services by integrating artificial intelligence and machine learning through Adobe Sensei, enhancing the capabilities of its vast product suite.
Naka-prepack na Software 152,667.60 693.00 282.80 503.67 356.70 41.19 88.10
557 BTDR / Bitdeer Technologies Group Mga Serbisyo sa Pananalapi 2,773.77 35.28 17.17 22.53 14.29 57.58 88.08
560 SRRK / Scholar Rock Holding Corporation
Scholar Rock Holding Corporation, based in the United States, operates primarily within the biopharmaceutical industry, focusing on the discovery and development of innovative medicines for serious diseases. The company specializes in targeting the supracellular activation of growth factors in the disease microenvironment, a novel approach that distinguishes it from other firms in the sector. Key projects include advances in therapies for spinal muscular atrophy and cancer, with its leading candidate, apitegromab, currently undergoing clinical trials aimed at treating spinal muscular atrophy to potentially enhance motor functions. Scholar Rock's research pipeline and clinical strategies are directed towards leveraging growth factor pharmacology to address unmet medical needs in oncology and rare diseases.
Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 3,134.39 56.70 45.45 51.58 32.65 58.04 88.03
563 TTD / The Trade Desk, Inc.
The Trade Desk, Inc., based in the United States, operates primarily in the digital advertising sector. As a global technology company, it specializes in designing and providing a software platform that enables buyers to manage data-driven digital advertising campaigns using various formats, including display, video, and social, across an array of devices such as computers, mobile devices, and connected TV. Renowned for its focus on transparency and effectiveness in advertising spend, The Trade Desk empowers advertisers through its proprietary technology which optimizes ad spending and enhances the targeting and effectiveness of marketing campaigns. Key projects often involve continuous advancements in programmatic ad buying techniques and developing partnerships with major publishers and platforms to maximize clients' advertising efficacy.
Computer Programming, Pagproseso ng Data, At Iba Pang Serbisyong Kaugnay ng Computer 26,777.82 141.75 45.45 77.10 54.66 41.05 88.00
564 SNSE / Sensei Biotherapeutics, Inc. Mga Paghahanda sa Parmasyutiko 10.13 105.00 35.35 68.85 8.03 88.00
566 PASG / Passage Bio, Inc. Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 22.00 126.00 10.10 65.54 6.92 819.14 87.96
567 MRUS / Merus N.V.
Merus N.V. is a biotechnology company based in the Netherlands, focusing primarily on developing innovative monoclonal antibody therapeutics. The company utilizes its proprietary Biclonics® technology platform to engineer bispecific antibodies, designed to recruit the immune system to kill cancer cells with high selectivity and efficacy. A key project of Merus is the development of MCLA-128 (zenocutuzumab), targeting HER2-expressing solid tumors, including colorectal and ovarian cancers, which has shown promising results in clinical trials. Merus's approach combines cutting-edge scientific research with strategic collaborations, aiming to address unmet medical needs in oncology by offering novel therapies that improve patient outcomes. The company's efforts are directed towards advancing a pipeline of targeted treatments through rigorous clinical development processes.
Mga Paghahanda sa Parmasyutiko 4,969.16 115.50 66.66 93.46 65.84 42.12 87.96
570 NVCR / NovoCure Limited
NovoCure Limited is a biotechnology company headquartered in the Isle of Man, primarily engaged in the development of medical devices for the treatment of various types of cancer. Its leading technology, Tumor Treating Fields (TTFields), employs electric fields aimed at disrupting cancer cell growth and division. This innovative treatment is marketed under the brand name Optune and has been primarily deployed in the fight against glioblastoma, an aggressive form of brain cancer. NovoCure is dedicated to expanding the application of its TTFields technology with ongoing clinical trials targeting other types of cancer, including mesothelioma and lung cancer. The company’s focus on leveraging its proprietary technology to improve outcomes in cancer treatment marks its key contribution to medical science and patient care in oncology.
Mga Instrumento at Apparatus ng Surgical at Medikal 1,379.60 39.90 14.64 28.05 12.33 127.31 87.95
574 INR / Infinity Natural Resources, Inc.
Infinity Natural Resources, Inc. is a U.S.-based company engaged in the exploration and development of natural resources, focusing on sustainable extraction and innovative mining techniques to unlock value from untapped mineral deposits.
227.01 30.45 21.21 25.50 14.90 71.16 87.93
578 ALIT / Alight, Inc.
Alight, Inc., based in the United States, operates primarily in the human capital and business solutions industry. The company offers technology-enabled services that help organizations manage health, wealth, HR, and finance needs. A significant aspect of Alight’s operations includes cloud-based solutions that integrate data analytics, artificial intelligence, and employee engagement platforms to optimize employer health care programs and investment solutions. Its key projects often involve partnerships with major cloud service providers to enhance enterprise resource planning (ERP) systems, transform human capital management (HCM), and streamline benefits administration. Alight’s strategic initiatives aim at delivering comprehensive, digitally-driven solutions that improve outcomes for both employers and their employees on a global scale.
Mga Serbisyo sa Negosyo, Hindi Nauuri sa Ibang Lugar 2,051.74 11.55 6.06 7.90 3.88 103.21 87.87
579 CRTO / Criteo S.A. - Depositary Receipt (Common Stock)
Criteo S.A. is a global technology company based in France, primarily specializing in digital marketing and advertising technology. The company operates in the internet software and services industry, focusing on providing machine learning-driven solutions that personalize online advertisements for internet users. Key projects at Criteo involve sophisticated algorithms for real-time ad personalization, which aim to enhance the effectiveness of digital advertising campaigns through targeted ads based on user behavior and preferences. Criteo's innovations extend to expanding their platform capabilities beyond mere ad retargeting to encompass a broader range of advertising technology solutions, catering to diversified markets and integrating seamlessly with various digital and e-commerce ecosystems.
Ahensya sa advertising 1,299.29 53.55 25.25 39.97 24.83 60.92 87.87
581 AMPX / Amprius Technologies, Inc. Miscellaneous Electrical Machinery, Equipment, and Supplies 886.79 18.90 10.10 13.26 7.09 86.89 87.86
582 OCUL / Ocular Therapeutix, Inc.
Ocular Therapeutix, Inc., based in the United States, operates within the biopharmaceutical industry, focusing primarily on the development and commercialization of innovative therapies for diseases and conditions of the eye. The company is known for employing its proprietary hydrogel technology platform to enhance ocular drug delivery, with a range of products aimed at addressing unmet needs in eye care. Key projects include DEXTENZA, an FDA-approved insert for the treatment of ocular pain and inflammation following ophthalmic surgery, and several other pipeline products targeting glaucoma, allergic conjunctivitis, and dry eye disease. Ocular Therapeutix continues to explore new applications of its technology to expand its product offerings and market reach.
Mga Paghahanda sa Parmasyutiko 2,111.42 23.10 14.14 17.90 12.21 46.69 87.86
584 SGMO / Sangamo Therapeutics, Inc.
Sangamo Therapeutics, Inc., based in the United States, operates within the biotechnology industry, specializing in genomic medicine. The company focuses on developing and commercializing transformative therapies targeting the underlying causes of genetic diseases. Key projects include gene therapy, cell therapy, and genome editing technologies. Notably, Sangamo has pioneered the application of its proprietary zinc finger nuclease (ZFN) genome editing technology, aiming to develop treatments for hemophilia and other genetic disorders. The firm actively collaborates with leading pharmaceutical companies to advance its research and clinical programs, positioning itself at the forefront of gene-edited cell therapy to potentially deliver curative treatments for severe genetic diseases.
Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 141.89 10.50 1.52 4.18 0.52 704.08 87.85
585 IONS / Ionis Pharmaceuticals, Inc.
Ionis Pharmaceuticals, Inc., based in the United States, operates prominently within the biopharmaceutical industry, focusing on the discovery and development of RNA-targeted therapies. The company has pioneered the use of antisense technology to create novel drugs capable of specifically targeting and regulating genes responsible for various diseases. A key element of Ionis's business model includes strategic partnerships with larger pharmaceutical entities to advance and commercialize its therapy candidates effectively. Among its notable projects, Ionis has developed treatments addressing a wide range of disorders, including cardiovascular, metabolic, and neurological diseases, and some of its drugs have progressed to late-stage clinical trials, reflecting significant potential for both clinical impact and revenue generation.
Mga Paghahanda sa Parmasyutiko 6,787.35 87.15 38.38 60.31 42.64 41.41 87.84
586 CCCC / C4 Therapeutics, Inc. Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 184.62 52.50 3.03 16.12 2.60 519.85 87.83
587 XAIR / Beyond Air, Inc.
Beyond Air, Inc. is a medical technology company based in the United States, specifically focused on developing innovative nitric oxide delivery systems for a variety of therapeutic applications. Situated primarily in the healthcare sector, its flagship projects center around the use of nitric oxide to treat acute and chronic respiratory conditions as well as certain infectious diseases. A key breakthrough from Beyond Air includes the LungFit® platform, a system capable of generating high concentrations of nitric oxide from ambient air to facilitate immediate on-site treatment. This technology emphasizes solutions for conditions like viral pneumonia, bronchiolitis, and nontuberculous mycobacterial lung infections. Through these advancements, Beyond Air aims to transform treatment paradigms and improve patient outcomes in multiple disease areas with unmet medical needs.
Mga Instrumento at Apparatus ng Surgical at Medikal 10.42 14.70 5.05 11.42 2.22 414.59 87.83
592 BDSX / Biodesix, Inc. Mga Medikal na Laboratoryo 63.13 2.10 1.52 1.78 0.43 314.44 87.78
595 GAMB / Gambling.com Group Limited
Gambling.com Group Limited is a digital marketing company based in Malta, specializing in the online gambling industry. The company operates as a performance marketing entity primarily within the regulated online gambling sector. It provides a range of marketing services to online gambling operators such as Search Engine Optimization, providing detailed operator reviews, and offering exclusive gambling bonuses directly from operators. Its key projects focus on facilitating user acquisition for betting and gaming operators in regulated markets. Gambling.com manages a portfolio of websites and apps that guide consumers in choosing their preferred regulated digital gambling services, comparing offerings like sports betting and casino games, thereby enhancing user engagement and maximizing revenue streams from affiliate marketing.
Sari-saring Libangan At Libangan 311.59 17.85 11.11 14.41 8.73 65.13 87.78
596 ADVM / Adverum Biotechnologies, Inc.
Adverum Biotechnologies, Inc., based in the United States, operates within the biotechnology industry, focusing on the development of gene therapy products. The company's primary project revolves around innovative therapies for ocular and rare diseases, using its proprietary vector platforms to address conditions like age-related macular degeneration. Adverum is pioneering in the area of adeno-associated virus (AAV) vectors, a technology that facilitates the delivery of genetic material into cells. Their lead product candidate, ADVM-022, is an investigational gene therapy designed for the treatment of wet age-related macular degeneration, representing a significant advancement in the field and demonstrating their commitment to addressing unmet medical needs through gene therapy solutions.
Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 64.62 34.65 4.04 20.14 3.08 547.75 87.76
597 DTIL / Precision BioSciences, Inc.
Precision BioSciences, Inc. is a biotechnology company based in the United States. Specializing in the development of gene editing technologies, the company operates primarily within the healthcare sector. It employs its proprietary ARCUS genome editing platform to develop therapies that can potentially treat a range of diseases, including genetically influenced ailments and various forms of cancer. Precision BioSciences focuses on both therapeutic and agricultural projects, aiming to enhance human health and food sustainability. Key initiatives include novel gene therapies for acute hepatitis B and immuno-oncology programs targeting lymphoma. Its innovative approach seeks to precise, minimize unwanted genetic edits, reflecting a significant advancement in the realm of genetic engineering.
Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 57.02 63.00 13.13 31.11 4.90 541.44 87.76
601 DXCM / DexCom, Inc.
DexCom, Inc., based in the United States, operates prominently within the healthcare sector, specializing in the design, development, and commercialization of continuous glucose monitoring (CGM) systems. Primarily serving patients with diabetes, DexCom's key projects center around the enhancement of diabetes management through advanced CGM products. These systems provide real-time insights into glucose levels, facilitating better therapy adjustments and serving both patients and healthcare providers with cutting-edge diagnostic and monitoring options. The company's ongoing commitment to innovation in medical technology underscores its strategic emphasis on expanding access to vital health data, thereby improving quality of life and treatment outcomes for diabetes sufferers worldwide.
Mga Instrumento at Apparatus ng Surgical at Medikal 29,548.35 126.00 85.07 105.40 75.34 40.00 87.73
602 CSTL / Castle Biosciences, Inc. Mga Medikal na Laboratoryo 695.84 43.05 30.30 36.34 24.01 51.22 87.73
608 CALC / CalciMedica, Inc. Mga Paghahanda sa Parmasyutiko 38.07 21.00 13.13 16.32 2.70 498.90 87.67
617 SCPH / scPharmaceuticals Inc.
scPharmaceuticals Inc., based in the United States, operates within the biopharmaceutical sector, primarily focusing on developing innovative subcutaneous formulations of proven therapies. The company aims to transform intravenous treatments into subcutaneous administrations, thus enhancing the convenience for patients and reducing healthcare delivery costs. Key projects include scFurosemide, a subcutaneous formulation of the diuretic furosemide targeted at patients with heart failure, and other treatments that emphasize outpatient care management. By reimagining existing drugs for subcutaneous delivery, scPharmaceuticals Inc. is positioned at the forefront of facilitating home-based treatment regimes, presenting a promising potential to disrupt traditional inpatient care models significantly.
Mga Paghahanda sa Parmasyutiko 293.10 26.25 11.11 15.91 5.50 189.31 87.59
619 CHRS / Coherus Oncology, Inc.
Coherus BioSciences, Inc., based in the United States, operates predominantly in the biotechnology industry, focusing on the development and commercialization of biosimilar therapies. The company aims to challenge the high cost of biologic medications in oncology and autoimmune diseases, offering more affordable patient access through reduced treatment expenses. Key projects include UDENYCA, a biosimilar to Neulasta, which aids in reducing the risk of infection during chemotherapy by boosting white blood cells. Furthermore, Coherus is involved in advancing a pipeline that includes biosimilars of leading drugs such as Humira and Avastin. These initiatives reflect its strategic focus on becoming a significant player in the biosimilar market, potentially transformative for both patient care and health economics.
Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 134.82 7.35 6.06 6.63 1.16 471.55 87.58
622 MSTR / Strategy Inc
MicroStrategy Incorporated, based in the United States, operates primarily within the business intelligence (BI) domain, providing software and related services that enable organizations to analyze internal and externally available data to make business decisions. Founded in 1989, the company has significantly expanded its portfolio to include cloud-based BI, mobile software, and HyperIntelligence, a technology designed to bring insights directly into everyday applications and tools without requiring users to seek them out actively. In recent years, MicroStrategy has also become prominent for its strategic acquisition of substantial holdings in Bitcoin, positioning itself uniquely at the intersection of traditional business intelligence services and innovative digital asset investment. This move reflects a broader vision to integrate cryptocurrency and blockchain technology within its core business offerings, highlighting its commitment to pioneering within the tech industry.
Mga Serbisyo sa Pananalapi 93,834.35 735.00 202.00 529.14 334.41 58.44 87.56
624 OPK / OPKO Health, Inc.
OPKO Health, Inc., based in the United States, operates primarily in the healthcare sector, focusing on pharmaceuticals and diagnostics. The company engages in the discovery, development, and commercialization of novel diagnostic technologies and pharmaceuticals. A key component of its pharmaceutical portfolio includes Rayaldee, a treatment for secondary hyperparathyroidism in patients with stage 3 or 4 chronic kidney disease. OPKO Health also heavily invests in the development of growth hormone-related treatments and has a robust pipeline in various therapeutic areas. Moreover, its diagnostics division, BioReference Laboratories, offers comprehensive laboratory testing services, playing a crucial role in the support of precision medicine and clinical trials. The firm aims to leverage its proprietary technologies and strategic collaborations to enhance patient care and expand its market reach.
Mga Paghahanda sa Parmasyutiko 1,076.10 8.92 2.02 3.98 1.38 189.31 87.55
625 LULU / lululemon athletica inc.
Lululemon Athletica Inc. is an athletic apparel retailer headquartered in Canada, primarily recognized for its high-performance activewear serving fitness enthusiasts globally. The company stands out in the retail sector for its innovative approach to sports clothing, particularly focusing on yoga-inspired attire. Key initiatives by Lulululemon include a robust digital marketing strategy, expansion into menswear and international markets, and a commitment to sustainability through eco-conscious product lines and practices. Additionally, Lululemon is expanding its digital presence by enhancing online consumer engagement and personalized shopping experiences, thereby reinforcing its market position in the competitive athleisure industry. Alongside retail expansion, the company also focuses on community events and wellness programs which align with its brand ethos of promoting a health-conscious lifestyle.
Kasuotan At Iba Pang Tapos na Mga Produktong Ginawa Mula sa mga Tela at Katulad na Materyal 24,269.06 525.00 156.55 290.11 202.20 43.46 87.52
631 NMG / Nouveau Monde Graphite Inc.
Nouveau Monde Graphite Inc. is a Canadian company engaged in the mining and processing of natural graphite. Headquartered in Quebec, Canada, the company aims to establish itself as a key player in the sustainable energy sector, specifically focusing on the production of high-quality graphite intended for use in lithium-ion batteries and other applications demanding this critical mineral. Key projects include the Matawinie graphite mining project, strategically located in Saint-Michel-des-Saints, Quebec, which promises to be the Western world's largest operating graphite mine once fully operational. Additionally, Nouveau Monde is developing advanced graphite processing capabilities, including the construction of a battery-materials plant that will support the burgeoning electric vehicle and renewable energy industries. Through vertical integration, Nouveau Monde Graphite Inc. strives to boost supply chain self-reliance for North American and global markets, emphasizing eco-friendly methods and transparency in operations.
Sari-saring Metal Ore Mining 295.39 4.42 2.66 3.49 1.95 79.68 87.48
638 SEAT / Vivid Seats Inc. Sari-saring Libangan At Libangan 115.32 155.82 18.18 39.31 17.75 122.16 87.43
640 JBIO / Jade Biosciences, Inc. 257.75 19.95 14.14 17.08 7.90 116.27 87.41
642 CRM / Salesforce, Inc.
Salesforce, Inc., headquartered in the United States, operates predominantly in the software industry, specializing in customer relationship management (CRM) services. The company's technology platform brings together a suite of tools including sales force automation, customer service, marketing automation, analytics, and application development capabilities designed to help businesses connect with their customers in new ways. Key initiatives include the integration of artificial intelligence through its Einstein platform, expansion into various cloud sectors with offerings such as Sales Cloud, Service Cloud, Marketing and Commerce Cloud, and more recently, its ventures into industry-specific solutions. This strategic direction strengthens its position as a leader in the CRM space, enabling seamless enterprise-level digital transformations. Salesforce is noted for its commitment to community engagement and sustainability, aligning its operations with corporate social responsibility principles.
Naka-prepack na Software 246,000.00 464.10 227.25 355.14 256.25 38.53 87.41
643 EXE / Expand Energy Corporation
Chesapeake Energy Corporation, based in the United States, is a prominent player in the hydrocarbon industry, focusing on the exploration, development, and production of petroleum and natural gas. Established in 1989 and headquartered in Oklahoma City, the company has undergone significant restructuring, particularly following a Chapter 11 bankruptcy in 2020, from which it emerged with a strategy centered on reducing debt and optimizing its portfolio. Chesapeake Energy's operations are primarily concentrated in top U.S. oil and gas plays such as the Marcellus Shale, Haynesville Shale, and Eagle Ford Shale. This strategic focus on major shale assets is part of its broader initiative to enhance operational efficiencies and shareholder value while adhering to stronger environmental and governance principles.
Crude Petroleum at Natural Gas 22,981.55 178.50 98.98 135.15 96.78 39.43 87.40
646 ALKS / Alkermes plc
Alkermes plc, based in Dublin, Ireland, is a prominent biopharmaceutical company focused on developing innovative medicines that address unmet needs in neuroscience and oncology. The company's portfolio revolves around central nervous system (CNS) disorders like schizophrenia, depression, and addiction. Key products include ARISTADA®, an extended-release injectable used to treat schizophrenia, and VIVITROL®, an injectable for alcohol and opioid dependence. Alkermes is actively involved in advancing a diverse pipeline of drug candidates, including a proprietary immuno-oncology drug, nemvaleukin alfa. The company's strategy emphasizes both internal product development and collaboration with external partners to enhance its R&D capabilities and drive growth within its therapeutic sectors.
Mga Paghahanda sa Parmasyutiko 4,779.99 56.70 30.30 42.84 28.97 47.93 87.35
649 MAZE / Maze Therapeutics, Inc. 636.28 35.70 17.17 24.99 14.49 72.23 87.29
652 PLTK / Playtika Holding Corp.
Playtika Holding Corp. is a digital entertainment company headquartered in Herzliya, Israel. Specializing in the development and publishing of mobile and social games, Playtika stands as a leader in the casino-style mobile games market. Founded in 2010, the company has leveraged its expertise in game design and player engagement to build a diverse portfolio of titles, including prominent games such as "Slotomania" and "House of Fun." These offerings are central to Playtika's business model, which focuses on leveraging its proprietary in-game technology to enhance player experience and retention. Playtika's innovative approach to the mobile gaming industry continues to facilitate its growth and cement its position as a significant player in the global digital entertainment landscape.
Mga Serbisyo sa Pagproseso ng Computer at Paghahanda at Pagproseso ng Data 1,392.31 14.70 4.04 6.52 3.71 76.13 87.24
657 LBRDK / Liberty Broadband Corporation
Liberty Broadband Corporation is an American company primarily engaged in the communications industry. Based in the United States, it functions as a holding company with significant interests in Charter Communications as well as a subsidiary, Skyhook, which specializes in location technology services. A core aspect of its business involves the management of its investment portfolio to optimize shareholder value and ensure sustained growth. The company’s strategic focus is heavily oriented towards maximizing its influence and operational capabilities within the broadband communications sector. Key projects typically include leveraging technological advancements to enhance broadband capabilities and exploring synergistic opportunities that align with its broad investment philosophy in the telecommunications spectrum.
Cable at Iba pang Pay Television Services 8,705.73 136.81 84.13 108.21 60.86 77.80 87.18
659 HRTX / Heron Therapeutics, Inc.
Heron Therapeutics, Inc., based in the United States, operates within the biotechnology industry, primarily focusing on developing treatments that address unmet medical needs in pain management and cancer care. A standout project is HTX-011, designed to decrease postsurgical pain and reduce the requirement for opioids in pain management. Another significant undertaking is the development of their CINV (Chemotherapy-Induced Nausea and Vomiting) franchise, featuring products such as CINVANTI and SUSTOL, aimed at improving patients' quality of life undergoing chemotherapy. Additionally, Heron works on several innovative therapies, including HTX-034 for postoperative pain and HTX-019 for CINV prevention, showcasing its commitment to pioneering advancements in patient care.
Mga Paghahanda sa Parmasyutiko 205.36 6.30 3.03 4.84 1.35 261.57 87.18
660 CWAN / Clearwater Analytics Holdings, Inc. Naka-prepack na Software 5,945.46 37.80 27.27 32.30 20.67 56.27 87.17
661 DRTS / Alpha Tau Medical Ltd. 289.15 13.65 5.05 8.92 3.42 162.50 87.17
663 MDXH / MDxHealth SA Mga Medikal na Laboratoryo 175.22 8.40 4.24 6.16 3.55 74.03 87.16
671 OM / Outset Medical, Inc. Electromedical at Electrotherapeutic Apparatus 247.48 40.95 17.17 26.26 13.91 88.55 87.13
684 URGN / UroGen Pharma Ltd. Mga Paghahanda sa Parmasyutiko 898.57 43.05 16.16 32.06 19.45 64.90 87.06
685 SOPH / SOPHiA GENETICS SA
SOPHiA GENETICS SA, based in Switzerland, operates primarily in the biotechnology sector, specializing in data-driven medicine and clinical genomics. The company leverages its AI-powered platform, SOPHiA, to analyze medical data and enhance the diagnostic accuracy for healthcare providers, thus enabling more targeted treatments in oncology, hereditary cancer, metabolism, pediatrics, and cardiology. A key project involves partnerships with hospitals and research institutions to improve cancer diagnostics and treatment strategies through genomic and radiomic analysis. By integrating deep learning into DNA sequencing, SOPHiA GENETICS aids in interpreting complex genetic data, promoting advancements in personalized medicine and optimizing clinical trials. With its focus on innovation in genomics, the company is central to transforming data into actionable insights in healthcare.
Mga Serbisyo sa Pagproseso ng Computer at Paghahanda at Pagproseso ng Data 229.09 9.45 6.06 7.14 3.46 110.62 87.04
686 CTRA / Coterra Energy Inc.
Coterra Energy Inc., based in the United States, is a prominent player in the oil and natural gas sector. The company primarily focuses on the exploration, development, and production of petroleum and natural gas resources. Coterra operates key assets in major energy-producing areas, including the Marcellus Shale, Permian Basin, and Anadarko Basin. These strategic locations are central to the company's operations and growth, allowing Coterra to leverage advanced drilling and extraction technologies to optimize production efficiency and resource recovery. As a leader in the energy industry, Coterra Energy Inc. combines innovative practices and environmental stewardship to enhance its operational footprint and market position while addressing the energy needs of a diverse client base.
Crude Petroleum at Natural Gas 18,647.72 40.95 27.27 33.96 24.44 38.96 87.04
694 MBLY / Mobileye Global Inc. 11,419.26 32.66 12.12 20.14 14.01 43.77 86.99
697 ARDT / Ardent Health, Inc. 1,815.92 24.15 12.12 20.09 12.69 58.35 86.98
700 TRDA / Entrada Therapeutics, Inc. Mga Paghahanda sa Parmasyutiko 193.92 21.00 17.17 18.87 5.47 245.92 86.97
710 CART / Maplebear Inc. 11,383.19 70.35 47.47 60.29 43.37 39.09 86.92
715 LUNG / Pulmonx Corporation
Nippon Steel Nisshin Co., Ltd., based in Japan, operates within the primary industry of steel production, distinguished as one of the largest steel producers in the world. Embodying a legacy of innovation and quality, the company focuses on a broad spectrum of steel products including specialty steel, sheets, and pipes. Key projects and initiatives under Nippon Steel Nisshin have traditionally centered around advancing technological integration in steel manufacturing processes, enhancing environment-friendly production methods, and pursuing global competitive edges through strategic alliances and expansions. The company plays a crucial role in driving the infrastructure and automotive sectors, amongst others, by providing high durability and precision-engineered steel products.
Mga Instrumento at Apparatus ng Surgical at Medikal 68.93 16.80 2.52 6.88 1.71 303.81 86.87
717 MCW / Mister Car Wash, Inc. Automotive Repair, Services, And Parking 1,868.64 11.55 6.06 8.45 5.71 47.97 86.86
718 FLUX / Flux Power Holdings, Inc. Miscellaneous Electrical Machinery, Equipment, and Supplies 25.57 8.40 4.04 5.86 1.52 284.59 86.85
721 BIRK / Birkenstock Holding plc
Birkenstock Holding plc, based in Germany, is a renowned global player in the footwear industry, primarily recognized for its sandals and other shoe products that emphasize orthopedic design. The company has built its reputation on the quality, comfort, and durability of its products, backed by a history stretching back to the 18th century. Birkenstock has expanded its presence worldwide by enforcing strong branding strategies and maintaining high production standards. The brand's dedication to sustainable manufacturing processes and the use of environmentally friendly materials distinguish it in the shoe industry. Key projects in recent years have focused on expanding market reach through strategic partnerships and enhancing direct-to-consumer sales channels, strengthening its hold as a leader in the footwear sector.
9,579.67 95.38 57.57 72.35 52.13 38.89 86.84
722 JAMF / Jamf Holding Corp.
Jamf Holding Corp., headquartered in Minneapolis, Minnesota, USA, is a prominent company in the software industry, specializing in Apple enterprise management. The corporation provides a comprehensive suite of solutions designed to help organizations manage Apple devices, ensuring security and enhancing user experience across businesses, educational institutions, and government entities. Key products include Jamf Pro, designed for IT professionals to automate the deployment, inventory, and security of macOS, iOS, and tvOS devices, and Jamf Now, which caters to smaller organizations requiring simplified device management. The company's focus on integrating and streamlining Apple device management in complex IT environments positions it as a critical facilitator of seamless enterprise-level Apple adoption and maintenance.
Naka-prepack na Software 1,237.00 24.15 10.10 15.21 9.32 63.17 86.84
723 MTVA / MetaVia Inc. Mga Paghahanda sa Parmasyutiko 15.35 22.05 3.03 14.02 0.63 2,111.10 86.81
724 NTNX / Nutanix, Inc.
Nutanix, Inc., based in the United States, operates primarily in the field of cloud computing, offering a comprehensive range of solutions designed to simplify data center operations. Its core product suite involves hyper-converged infrastructure (HCI) software, cloud services, and software-defined storage, which allow enterprises to integrate their IT resources, manage virtual environments, and transition to multicloud systems efficiently. Key projects under Nutanique's banner typically focus on enhancing application mobility and data management across both private and public clouds, facilitating seamless hybrid and multicloud strategies for businesses. Through these technological solutions, Nutanix enables improved scalability, performance, and cost-efficiency in organizational IT infrastructure.
Naka-prepack na Software 18,056.57 105.00 84.95 94.31 67.21 40.33 86.79
736 HROW / Harrow, Inc. Mga Paghahanda sa Parmasyutiko 1,431.14 79.80 42.42 61.03 39.00 56.56 86.73
737 ZYME / Zymeworks Inc. Mga Paghahanda sa Parmasyutiko 1,108.47 31.50 13.13 23.18 14.81 56.33 86.71
738 BFLY / Butterfly Network, Inc. X-Ray Apparatus at Tubes at Kaugnay na Irradiation Apparatus 404.17 4.20 2.02 3.32 1.61 104.63 86.71
741 LFST / LifeStance Health Group, Inc. Health Services 2,136.03 10.50 6.56 8.60 5.48 56.60 86.70
746 VERX / Vertex, Inc. Naka-prepack na Software 4,114.06 56.70 25.25 38.48 25.82 49.08 86.67
747 STRO / Sutro Biopharma, Inc.
Sutro Biopharma, Inc., based in the United States, operates predominantly in the biopharmaceutical industry, focusing on the design and development of innovative oncology therapeutics and biotherapeutics. The company leverages its proprietary integrated cell-free protein synthesis platform, XpressCF, to produce novel protein therapeutics that have enhanced therapeutic profiles for cancer treatments. Key projects include a variety of monoclonal antibodies and antibody-drug conjugates aimed at targeted cancer therapy, such as STRO-001 and STRO-002, which are in clinical trials targeting CD74 and folate receptor alpha, respectively. Sutro Biopharma's commitment to advancing oncology treatment options with precision underpins its ongoing research and development efforts.
Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 72.61 7.35 0.81 3.18 0.86 269.33 86.67
752 CAVA / CAVA Group, Inc. Mga Restaurant, Kainan, at Lugar ng Kainan 7,821.14 131.25 72.72 94.37 67.55 39.70 86.63
760 FEMY / Femasys Inc. Mga Instrumento at Apparatus ng Surgical at Medikal 11.63 8.40 3.03 6.38 0.36 1,695.27 86.58
761 ALDX / Aldeyra Therapeutics, Inc. Mga Paghahanda sa Parmasyutiko 350.67 13.65 6.06 9.69 5.84 66.07 86.56
762 DEC / Diversified Energy Company PLC
Diversified Energy Company PLC is an energy company based in the United Kingdom, primarily engaged in the acquisition and management of mature gas and oil producing assets. The company focuses on maximizing the profitability of its assets in the Appalachian Basin across the United States, emphasizing reliable production and operational efficiency. Diversified Energy is also involved in the implementation of environmental management projects, such as its carbon offset programs and methane reduction initiatives, to enhance its sustainable energy practices. These projects align with the company’s strategy to leverage long-life, low-decline assets while maintaining a strong commitment to environmental stewardship and shareholder value.
1,281.61 43.62 15.39 28.60 16.47 73.56 86.56
769 EXAS / Exact Sciences Corporation
Exact Sciences Corporation, based in the United States, operates primarily in the diagnostics and research industry focusing significantly on the detection and prevention of cancer. It is renowned for developing Cologuard, an FDA-approved non-invasive stool DNA screening test for colorectal cancer. The company is also expanding its portfolio through innovation and acquisitions, such as its purchase of molecular diagnostics company Genomic Health, enhancing its capabilities in cancer genetics and precision oncology. Additionally, Exact Sciences is advancing in the development of multi-cancer screening technologies that aim to detect various types of cancer from a single blood sample, positioning the company at the forefront of cancer diagnostics research and applications.
Mga Medikal na Laboratoryo 8,974.73 84.00 46.46 64.66 47.42 36.34 86.53
771 IE / Ivanhoe Electric Inc. Pagmimina ng Metal 1,183.60 21.00 13.13 15.64 8.92 75.73 86.52
773 VCEL / Vericel Corporation Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 1,834.03 65.10 45.45 54.95 36.36 51.13 86.51
774 TELA / TELA Bio, Inc. Mga Instrumento at Apparatus ng Surgical at Medikal 70.46 7.35 2.02 5.51 1.78 211.19 86.51
777 QXO / QXO, Inc.
QXO, Inc. is a U.S.-based company that specializes in providing innovative software solutions for enterprise-level organizations. The company focuses on optimizing business processes through automation and advanced analytics tools to enhance operational efficiency and decision-making.
Lumber And Other Construction Materials 13,519.31 46.20 27.27 32.90 20.13 63.49 86.48
778 RELY / Remitly Global, Inc. Electrical Apparatus and Equipment Wiring Supplies, and Construction Materials 3,820.93 33.60 26.26 29.61 18.53 59.69 86.48
779 RAPP / Rapport Therapeutics, Inc. 642.72 44.10 28.28 34.88 17.63 98.09 86.48
787 IMRX / Immuneering Corporation Mga Paghahanda sa Parmasyutiko 205.85 22.05 8.08 13.06 5.75 128.25 86.41
790 RPID / Rapid Micro Biosystems, Inc. Mga Instrumentong Analitikal sa Laboratory 106.63 8.40 8.08 8.16 2.41 237.19 86.38
792 FI / Fiserv, Inc.
Fiserv, Inc., headquartered in the United States, operates primarily within the financial services technology industry. The company offers a broad range of payment and financial services technology solutions, aiming to optimize transactions and business operations for various financial institutions, including banks, credit unions, and other corporate entities. Key projects and services from Fiserv include electronic payments processing, the Clover payment platform, and digital banking solutions designed to enhance user experience and operational efficiency. The company's innovation extends into areas such as fraud management, analytics, and mobile banking technology, supporting its extensive global client base with advanced, scalable solutions tailored to the dynamic landscape of financial services.
Mga Serbisyo sa Larangan ng Langis at Gas, Hindi Nauuri sa Ibang Lugar 76,372.09 262.50 126.25 187.41 138.18 35.63 86.36
794 PRMB / Primo Brands Corporation 9,378.23 44.10 26.26 36.41 25.11 44.96 86.36
796 INUV / Inuvo, Inc.
Inuvo, Inc., based in the United States, is a technology firm that operates primarily within the digital advertising sector. The company specializes in developing and utilizing artificial intelligence (AI) to optimize digital marketing campaigns across multiple platforms, aiming to improve the effectiveness of targeted ads. Inuvo's key projects include the IntentKey, a proprietary machine-learning technology that predicts user intent, and the ValidClick platform, which provides advertising solutions tailored for specific demographics to enhance engagement rates. These innovations underscore Inuvo's commitment to leveraging state-of-the-art technology for refining digital advertising strategies, thereby enriching the connection between advertisers and consumers.
Advertising 49.07 15.75 10.10 12.37 3.39 263.64 86.34
801 SVCO / Silvaco Group, Inc.
Founded in 1984 and headquartered in Santa Clara, California, USA, Silvaco Group, Inc. is a leading technology company specializing in electronic design automation (EDA) software. The company primarily serves the semiconductor industry, providing advanced tools used in the design and simulation of semiconductors, displays, and electronics. Silvaco's suite of products supports the complete design process, from TCAD (Technology Computer-Aided Design) through to sign-off, covering a range of applications such as power electronics and IC design. Over the years, Silvaco has consistently expanded its product lineup and global footprint, collaborating on key projects with prominent semiconductor manufacturers to drive innovations in integrated circuit design. Their comprehensive solutions support both established and emerging technologies, underlining their crucial role in the evolving digital landscape.
157.79 12.60 6.06 9.86 5.34 84.99 86.32
805 EVGO / EVgo, Inc. Automotive Repair, Services, And Parking 518.86 12.60 4.04 6.74 3.87 74.51 86.27
810 PAYO / Payoneer Global Inc. Mga Serbisyo sa Negosyo, Hindi Nauuri sa Ibang Lugar 2,513.92 12.60 8.08 10.02 6.95 44.38 86.23
811 CHYM / Chime Financial, Inc. 9,795.92 44.10 35.35 39.47 26.41 49.41 86.22
813 SIBN / SI-BONE, Inc.
SI-BONE, Inc., based in the United States, operates within the medical device industry, specializing primarily in innovative surgical treatments for the sacroiliac joint. The company is renowned for its development and commercialization of the iFuse Implant System, a minimally invasive surgical system designed to provide stabilization and fusion of the sacroiliac joint. This patented technology has significantly impacted the treatment of lower back pain associated with sacroiliac joint dysfunction, a common yet under-diagnosed condition. SI-BONE’s focus on clinical education and providing evidence-based solutions has positioned it as a leader in this specialized segment of orthopedic surgery, catering to a growing patient population seeking alternative solutions to chronic pain.
Mga Instrumento at Apparatus ng Surgical at Medikal 713.28 33.60 20.20 25.50 16.67 53.02 86.20
814 CHTR / Charter Communications, Inc.
Charter Communications, Inc., based in the United States, is a leading telecommunications and mass media company primarily servicing residential and commercial customers through its broadband communications services. Within the telecommunications industry, Charter operates under the brand name Spectrum, providing a range of services including cable television, high-speed internet, and telephone services. The company has been heavily involved in expanding its broadband network, emphasizing enhancements in internet download speeds and cable service upgrades. Key projects include the integration of advanced wireless technology like 5G to complement their existing infrastructure and the expansion of fiber connectivity to underserved areas, demonstrating Charter's commitment to becoming a comprehensive multi-platform connectivity provider.
Cable at Iba pang Pay Television Services 36,275.83 735.00 232.30 419.97 265.58 58.13 86.20
815 MRVI / Maravai LifeSciences Holdings, Inc.
Maravai LifeSciences Holdings, Inc., based in the United States, is a key player in the life sciences sector, focusing primarily on providing reagents for researchers and companies engaged in the development of therapeutic drugs, diagnostics, and novel vaccines. Notably, Maravai LifeSciences has gained recognition for its pivotal role in the production of specialized reagents that are essential for mRNA-based therapies, including vaccines. One of its major projects includes supplying critical components for COVID-19 vaccines, which underscores its impact in battling the global pandemic. The company operates through subsidiaries that specialize in different niches within the broader biotechnology and pharmaceutical fields, enhancing its ability to support various aspects of medical research and public health initiatives.
Mga Paghahanda sa Parmasyutiko 349.25 5.25 2.02 4.21 2.42 74.22 86.19
816 KMTS / Kestra Medical Technologies, Ltd. 828.25 31.50 20.20 27.37 16.14 69.68 86.18
820 MDWD / MediWound Ltd.
MediWound Ltd. is a biopharmaceutical company based in Israel, specializing in the development, manufacture, and commercialization of novel products to address unmet needs in the fields of severe burns, chronic wound management, and connective tissue disorders. The company's flagship product, NexoBrid, is an innovative enzymatic treatment that selectively removes burnt tissue in patients with severe burns. It has gained regulatory approval and market access in multiple international territories. Additionally, MediWound is actively working on expanding its product portfolio with EscharEx, a topically applied cream for debridement of chronic and other hard-to-heal wounds, which is currently in advanced stages of clinical trials. The company's focus on enzymatic technology underpins its therapeutic advancements, aligning with its strategic vision to lead in specialized wound care solutions.
Bahan Kimia Obat dan Produk Botani 181.41 40.95 25.25 31.28 16.70 87.53 86.17
823 AXGN / Axogen, Inc.
AxoGen, Inc., based in the United States, operates primarily in the healthcare sector, focusing on the development and commercialization of technologies for peripheral nerve regeneration and repair. The company is a pioneer in offering an extensive portfolio of products such as Avance® Nerve Graft, which leverages human tissue for bridging nerve discontinuities, AxoGuard® Nerve Connector and AxoGuard® Nerve Protector for nerve protection and reconstruction, and AxoTouch®, an electrodiagnostic device for nerve function assessment. These innovative solutions are geared towards numerous surgical nerve repair needs, catering to both trauma and surgical reconstruction markets. AxoGen is committed to advancing the science of nerve repair and improving the quality of life for patients affected by nerve injuries.
Electromedical at Electrotherapeutic Apparatus 738.42 31.50 20.20 25.37 16.14 57.25 86.15
830 SEI / Solaris Energy Infrastructure, Inc.
Solaris Oilfield Infrastructure, Inc., based in the United States, operates primarily within the energy sector, focusing on providing innovative logistics and infrastructure solutions to enhance the efficiency and safety of oilfield operations. The company specializes in the manufacture and delivery of mobile proppant management systems which are pivotal in hydraulic fracturing activities across North American shale plays. A key project for Solaris includes their proprietary Solaris Mobile Proppant Management System, designed to significantly cut down on the costs and environmental impact associated with sand handling in oilfield operations. This system underscores their commitment to sustainability through reduced truck demurrage and improved storage capabilities, aligning industry needs with environmental stewardship.
Makinarya at Kagamitan sa Oil and Gas Field 1,194.67 53.55 38.38 46.83 31.59 48.33 86.13
831 TALK / Talkspace, Inc. Health Services 446.47 6.30 3.54 4.90 2.66 83.71 86.11
836 EVEX / Eve Holding, Inc. Sasakyang panghimpapawid 1,170.69 8.40 6.82 7.50 3.93 90.28 86.10
839 GLBE / Global-E Online Ltd. Naka-prepack na Software 5,669.25 67.20 32.32 48.18 33.46 44.28 86.09
841 BRBR / BellRing Brands, Inc.
BellRing Brands, Inc., based in the United States, operates predominantly in the health and wellness sector, focusing on the development, marketing, and distribution of protein and nutrition products. Founded as a subsidiary of Post Holdings, Inc., BellRing targets active lifestyle consumers by offering ready-to-drink protein shakes, powdered protein products, and nutrition bars. The company's strategic direction includes enhancing its core brands like Premier Protein and Dymatize through product innovation and market expansion. This strategy manifests in continuously evolving product formulations that meet specific nutritional demands and leveraging robust distribution networks to reinforce its market presence. BellRing's key projects typically revolve around expanding its product portfolio and entering new domestic and international markets to capitalize on growing health-conscious consumer bases.
Pagkain At Mga Kamag-anak na Produkto 5,196.93 92.40 40.40 57.39 41.05 39.84 86.08
844 KRYS / Krystal Biotech, Inc.
Krystal Biotech, Inc., based in the United States, operates within the biotechnology industry with a primary focus on developing and commercializing gene therapies. A cornerstone of their work lies in the utilization of their proprietary gene therapy platform, STAR-D (Skin TARgeted Delivery), which is engineered for treating dermatological diseases. A key project includes their lead product candidate, Vyjuvek, designed for treating dystrophic epidermolysis bullosa, a rare and often devastating skin disorder. Beyond dermatology, Krystal Biotech is exploring applications of their technology in treating other diseases with unmet medical needs, paralleling efforts to expand their therapeutic reach and enhance patient care in underserved medical areas.
Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 4,272.52 264.60 167.66 210.21 147.70 42.42 86.06
846 SMMT / Summit Therapeutics Inc.
Summit Therapeutics Inc. is a biopharmaceutical company focused on the discovery, development, and commercialization of patient, physician, caregiver, and societal-friendly medicinal therapies intended to improve quality of life, increase potential duration of life, and resolve serious unmet medical needs. The Company’s pipeline of product candidates is designed with the goal to become the patient-friendly, new-era standard-of-care medicines, in the therapeutic area of oncology.
Mga Paghahanda sa Parmasyutiko 17,611.95 46.20 12.12 35.19 23.70 48.42 86.06
847 APLS / Apellis Pharmaceuticals, Inc.
Apellis Pharmaceuticals, Inc., based in the United States, operates within the biopharmaceutical sector, primarily focusing on innovative therapeutic treatments for autoimmune and inflammatory diseases. The company has pioneered the use of complement C3 inhibition technology, introducing a robust pipeline of drug candidates aimed at addressing a wide range of debilitating diseases with significant unmet medical needs. A key product, Pegcetacoplan, targets conditions like paroxysmal nocturnal hemoglobinuria and has extended its applications into geographic atrophy, underscoring Apellis' strategic reach in both rare diseases and broader medical conditions. Apellis' commitment to expanding treatment possibilities across various diseases makes it a notable entity in the biopharmaceutical landscape, poised for potential growth and clinical advancements.
Mga Paghahanda sa Parmasyutiko 3,478.98 63.00 19.19 38.53 27.57 39.61 86.06
849 ALUR / Allurion Technologies Inc.
Allurion Technologies Inc. is a U.S.-based medical device company specializing in innovative weight loss solutions. The company’s flagship offering, the Allurion Program, includes a swallowable, non-invasive intragastric balloon for weight management, combined with AI-powered patient monitoring tools and a behavioral change program.
Mga Instrumento at Apparatus ng Surgical at Medikal 16.82 65.62 6.06 23.84 2.17 1,003.82 86.03
851 BIOX / Bioceres Crop Solutions Corp.
Bioceres Crop Solutions Corp., headquartered in Rosario, Argentina, operates primarily in the agricultural biotechnology sector. The company develops and provides crop productivity solutions designed to enable the transition of agriculture towards carbon neutrality. These solutions include seed treatments, genetic improvements, and crop protection products that enhance yields while reducing environmental impact. Key projects include the development of drought-resistant crops under the HB4 technology, which represents a significant advancement in agronomic traits for vital crops such as soybeans and wheat. Through strategic partnerships and advanced biotechnological research, Bioceres aims to address critical challenges in sustainable agriculture on a global scale.
Mga Kemikal na Pang-agrikultura 174.58 9.45 6.06 7.52 2.79 170.59 86.03
858 CRVO / CervoMed Inc. Mga Paghahanda sa Parmasyutiko 89.75 32.55 14.14 20.91 9.62 115.57 86.00
859 OFSTF / Carbon Streaming Corporation
Carbon Streaming Corporation is a Canadian-based investment company primarily engaged in the climate finance sector, focusing on acquiring and managing carbon credits from global projects that adhere to the standards set by the voluntary and compliance carbon markets. By leveraging a unique financing model akin to the streaming contracts commonly used in the mining industry, Carbon Searching Corporation invests in projects that generate or are actively working towards generating verified carbon credits. These projects span various geographies and concentrate on impactful areas including reforestation, renewable energy, and methane capture. Key initiatives include the Misahara Cerrado Biome REDD+ Project and the Green Trees Reforestation Project, both aiming to significantly reduce carbon emissions and promote sustainability through ecological conservation and restoration efforts.
29.61 0.56 86.00
876 INAB / IN8bio, Inc.
IN8bio, Inc. is a biotechnology firm based in the United States, primarily focused on the development of cancer therapeutics. The company specializes in the innovation of novel treatments using gamma-delta T cells, a type of immune cell with potential anti-cancer properties. A key project of IN8bio is its research and development of "Drug Resistant Immunotherapy" (DRI), designed to enhance the efficacy and safety of cancer treatments that involve chemotherapy alongside cell therapies. Their work also extends to exploring the potential of these treatments in various cancer types, including acute leukemia and solid tumors. This positions IN8bio as a significant player in the oncology segment, seeking to leverage cutting-edge science to improve outcomes for cancer patients.
Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 8.93 236.25 36.36 127.76 2.21 5,733.56 85.86
884 OCGN / Ocugen, Inc.
Ocugen, Inc., headquartered in Malvern, Pennsylvania, operates in the biopharmaceutical industry and focuses primarily on developing gene therapies to cure blindness diseases and developing a vaccine to save lives from COVID-19. Established with a vision to address unmet needs in ocular therapies, Ocugen has pivoted its expertise toward vaccine development amidst the global pandemic. The company's notable projects include a partnership with Bharat Biotech to co-develop Covaxin™, a COVID-19 vaccine, for the U.S. market. Alongside, its ophthalmologic portfolio features innovative gene therapy candidates aimed at treating diseases like Retinitis Pigmentosa and other degenerative eye diseases, leveraging its breakthrough modifier gene therapy platform and other biologic product candidates.
Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 298.04 8.40 4.04 6.63 1.02 550.00 85.82
885 CBIO / Crescent Biopharma, Inc. 281.52 29.40 22.22 26.01 14.40 80.00 85.80
887 WEST / Westrock Coffee Company Peralatan Pemanas, Kecuali Tungku Listrik dan Udara Hangat 512.37 13.65 10.10 11.02 5.41 103.62 85.80
889 HASI / HA Sustainable Infrastructure Capital, Inc.
Hannon Armstrong Sustainable Infrastructure Capital, Inc., based in the United States, operates primarily in the financial services industry with a focus on investment in sustainable infrastructure projects. The company specializes in providing capital to assets that reduce carbon emissions or increase energy efficiency, including projects related to renewable energy, energy efficiency, and sustainable infrastructure. Key projects typically involve partnerships with other companies and government entities and span across both the public and private sectors. Hannon Armstrong's investments include solar and wind facilities, energy-efficient buildings, and infrastructure for electric vehicle charging. The company seeks to generate returns through interest income, lease payments, and gains on investments, supporting its sustainability-focused financial objectives.
Mga Namumuhunan, Hindi Nauuri sa Ibang Lugar 3,475.31 50.40 27.27 38.98 28.24 38.08 85.79
894 HCAT / Health Catalyst, Inc.
Health Catalyst, Inc., based in the United States, operates within the healthcare technology sector. The company specializes in providing data and analytics technology and services to healthcare organizations, aiming to improve healthcare outcomes while lowering costs. Health Catalyst's solutions encompass data warehousing, analytics, and outcome improvement, which are integral to supporting healthcare institutions in their operational, financial, and clinical decision-making processes. Key projects typically involve the implementation of advanced analytical tools and data-driven strategies in hospitals and other healthcare settings to enhance efficiency, reduce waste, and improve patient care. These projects illustrate Health Catalyst’s commitment to leveraging technology for substantial healthcare advancements, making significant strides in transforming clinical data into actionable insights.
Computer Programming, Pagproseso ng Data, At Iba Pang Serbisyong Kaugnay ng Computer 237.50 9.45 3.03 5.44 3.39 60.95 85.77
898 KROS / Keros Therapeutics, Inc. Mga Paghahanda sa Parmasyutiko 617.76 36.75 15.15 23.46 15.21 54.39 85.75
899 SY / So-Young International Inc. - Depositary Receipt (Common Stock) Mga Serbisyo sa Pagproseso ng Computer at Paghahanda at Pagproseso ng Data 381.39 10.79 5.56 8.05 3.84 109.58 85.74
905 CREX / Creative Realities, Inc.
Creative Realities, Inc., based in the United States, operates within the digital marketing solutions industry, focusing specifically on digital signage solutions. The company provides a blend of technology and services that cater to the design, installation, and management of digital networks for a broad array of global clients across multiple sectors, including retail, automotive, and fast food. Key projects typically involve the integration of technologies like digital displays, interactive kiosk solutions, and mobile applications to enhance consumer engagement and optimize operational efficiency. Creative Realities' approach emphasizes tailored, data-driven solutions that help businesses harness the full potential of digital signage and advertising technologies to achieve specific marketing objectives.
Computer Integrated Systems Design 25.25 10.50 4.54 6.76 2.39 181.56 85.72
906 NVCT / Nuvectis Pharma, Inc. Mga Paghahanda sa Parmasyutiko 156.40 26.25 10.10 18.53 6.56 182.90 85.72
910 CNDT / Conduent Incorporated
Conduent Incorporated, based in the United States, operates primarily within the business process services sector. This company was established as a result of a spin-off from Xerox Corporation in 2017. Conduent offers a diversified array of services which include digital payment systems, automated tolling, customer care, and healthcare solutions. Particularly notable are its key projects in the transport sector, such as providing automated tolling systems which enhance infrastructure efficiency and streamline user interactions. The firm harnesses technology to innovate traditional processes and supports governmental and commercial clients to optimize their operations. Conduport is pivotal in driving digital transformation by leveraging cloud computing, machine learning, and advanced data analytics to enhance service delivery and operational efficiencies across multiple industries.
Mga Serbisyo sa Negosyo, Hindi Nauuri sa Ibang Lugar 442.46 7.46 6.77 7.09 2.78 155.00 85.71
912 CDNA / CareDx, Inc
CareDx, Inc., based in the United States, operates primarily within the healthcare sector, focusing on advanced diagnostic solutions tailored specifically for transplant patients. The company is at the forefront of molecular diagnostics and offers a suite of services designed to improve the outcomes of organ transplantations through better monitoring and detection of potential complications. Key products include AlloMap, a non-invasive blood test that helps clinicians assess the risk of organ rejection, and AlloSure, which detects donor-derived cell-free DNA, serving as a significant indicator of organ health post-transplant. CareDx also invests significantly in digital solutions and remote monitoring platforms, enhancing its approach to comprehensive transplant care management.
Mga Medikal na Laboratoryo 726.99 29.40 14.14 22.95 13.66 68.01 85.69
914 HAE / Haemonetics Corporation
Haemonetics Corporation, based in Boston, Massachusetts, USA, operates primarily in the healthcare sector, focusing on blood and plasma supplies and services. This company is a global leader in blood management solutions, playing a pivotal role in the manufacturing and development of a comprehensive suite of products designed for blood collection, separation, and processing. A key project for Haemonetics is the advancement of its plasma collection systems, which enhance efficiency and safety in plasma collection—a critical component in the production of biopharmaceuticals. Strengthening its market position, Haemonetics also concentrates on innovative technologies that aim to improve patient outcomes and offer integrated approaches to blood management for health systems around the world.
Mga Instrumento at Apparatus ng Surgical at Medikal 2,626.58 113.40 58.58 81.91 54.54 50.13 85.68
915 BUR / Burford Capital Limited
Burford Capital Limited is a global finance firm headquartered in the United States, primarily engaged in providing litigation finance and a broader spectrum of legal finance and advisory services. They stand as a pioneer in the niche market of litigation finance, where they invest in legal cases and disputes in exchange for a share of any potential financial settlements. The company's key projects typically include financing high-stake commercial lawsuits, arbitration, and competition cases. Since its foundation, Burford Capital has expanded its reach, catering to law firms, businesses, and individuals across various jurisdictions, thereby emphasizing its role as a critical player in transforming how legal outcomes are financially managed and leveraged.
Mga Serbisyo sa Pananalapi 3,063.23 31.70 18.08 23.65 14.00 68.92 85.68
924 ETOR / eToro Group Ltd. 3,564.99 89.25 50.50 69.50 44.40 56.49 85.58
925 DC / Dakota Gold Corp.
Dakota Gold Corp. is a U.S.-based company primarily engaged in the mining industry, specializing in the exploration and development of gold properties. The company's operations are primarily focused in the Homestake District of South Dakota, a region renowned for its rich gold mining history. Dakota Gold Corp. actively explores and develops various projects within this area, leveraging both historical data and modern technology to optimize their gold recovery efforts. Key projects include the acquisition and assessment of properties such as Maitland, West Corridor, and Ragged Top, all of which are pivotal to the company's strategy of resource expansion and sustainable development within the gold mining sector. These projects demonstrate Dakota Gold Corp.'s commitment to advancing their portfolio through strategic exploration and targeted geological research.
Pagmimina ng Metal 468.13 12.60 9.09 10.71 4.17 156.22 85.58
928 PALI / Palisade Bio, Inc.
Palisade Bio, Inc. is a biopharmaceutical company based in the United States, primarily focused on the development of therapeutics to address acute and chronic gastrointestinal (GI) complications stemming from post-operative digestive enzyme damage. The company is chiefly engaged in advancing its portfolio through clinical trials aimed at enhancing recovery and preventing complications following GI surgery. One of their key projects includes the development of an investigational drug, LB1148, which is designed to accelerate the return of GI function post-surgery, potentially reducing the need and associated risks of intravenous nutrition and opioids. This focus is part of Palisade Bio’s broader strategy to address significant unmet medical needs in post-operative care.
Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 3.24 14.70 2.02 8.16 0.68 1,107.46 85.56
930 CING / Cingulate Inc. Mga Paghahanda sa Parmasyutiko 19.41 64.05 8.08 29.38 3.99 639.95 85.55
935 WTTR / Select Water Solutions, Inc.
Select Water Solutions, Inc., based in the United States, operates within the environmental and utility sector, primarily focusing on water treatment and management solutions. The company has carved a niche in developing advanced technologies that aid in the purification and reuse of industrial and municipal wastewater. Key projects highlight their expertise in integrating eco-friendly treatment systems that significantly reduce water consumption and minimize environmental impact. These initiatives not only support sustainable water resource management but also provide cost-effective solutions tailored for specific industry needs. The firm’s continuous innovation in water treatment technologies positions it as a pivotal player in promoting sustainable practices within the water management industry.
Mga Serbisyo sa Larangan ng Langis at Gas, Hindi Nauuri sa Ibang Lugar 865.01 15.75 10.10 14.28 8.52 67.51 85.53
939 BNTX / BioNTech SE - Depositary Receipt (Common Stock)
BioNTech SE, based in Germany, operates primarily in the biotechnology industry, focusing on developing transformative medicines using a range of computational and therapeutic technologies. The company made significant global impact through its development of one of the first widely-approved COVID-19 mRNA vaccines, in partnership with Pfizer. Beyond its notable contributions to vaccine development, BioNTech SE is engaged in multiple projects across oncology and infectious disease management, employing proprietary technologies such as mRNA, cell therapies, and monoclonal antibodies. Its innovative approach aims to individualize cancer medicine and enhance the effectiveness of immune-activating therapies in various diseases, reflecting its broader mission to provide next-generation treatments for cancer and other serious diseases.
Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 24,039.87 179.55 82.93 136.79 100.00 36.79 85.51
940 VNRX / VolitionRx Limited Mga In Vitro at In Vivo Diagnostic Substances 71.75 5.25 2.02 3.19 0.69 362.40 85.50
941 DAR / Darling Ingredients Inc.
Darling Ingredients Inc., based in the United States, operates within the sustainability and agribusiness sectors by transforming animal and food waste into usable products like feed, fuel, and natural fertilizers. As a global leader in their industry, they implement innovative technologies to process organic residuals, producing ingredients critical to the pharmaceutical, food, pet food, and agriculture industries. A key project for Darling Ingredients is their production of renewable diesel through a joint venture named Diamond Green Diesel, which significantly underscores their strategic initiatives toward reducing carbon footprint and supporting circular economy principles. This initiative highlights their commitment to sustainability by converting waste into clean energy, aligning with global environmental goals.
Taba at mantika 5,374.59 63.00 34.34 48.35 33.96 42.47 85.50
943 SRTS / Sensus Healthcare, Inc.
Sensus Healthcare, Inc., based in the United States, operates primarily within the medical technology industry, specializing in non-invasive treatments for both oncological and non-oncological conditions. The company is renowned for its innovative approach in developing low-energy X-ray systems, particularly the SRT-100™, which is designed for superficial radiotherapy. This technology has prominently been utilized in effectively treating non-melanoma skin cancers and keloids, with a focus on enhancing patient comfort and treatment efficacy. The company’s portfolio extends to include products like the Sculptura™, which offers radiotherapy solutions specifically tailored for breast cancer, demonstrating Sensus Healthcare's commitment to advancing oncological care through targeted radiological therapies.
Mga Instrumento at Apparatus ng Surgical at Medikal 55.90 10.50 6.06 8.16 3.39 140.00 85.48
944 AUNA / Auna S.A.
Auna S.A., based in Peru, operates as a prominent player in the healthcare and telecommunications sectors. Within healthcare, Auna owns and manages a network of hospitals and clinics providing comprehensive medical services across the region. In telecommunications, the company focuses on offering internet, cable television, and related services, highlighting its diversified business model. Key projects for Auna include the expansion of its healthcare facilities to enhance accessibility and capacity, alongside upgrading its technological infrastructure to support the growing demand for high-speed internet and digital services. These initiatives underscore Auna's commitment to improving regional infrastructure and healthcare accessibility, reflecting its strategic role in fostering socio-economic development in Peru.
467.46 19.95 7.07 12.04 6.29 91.05 85.47
945 PRVA / Privia Health Group, Inc. Health Services 2,825.17 38.85 21.21 30.96 23.04 34.42 85.47
949 PAYS / Paysign, Inc. Mga Serbisyo sa Negosyo, Hindi Nauuri sa Ibang Lugar 281.31 10.50 7.07 8.98 5.18 73.62 85.45
951 INTS / Intensity Therapeutics, Inc. Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 7.41 5.25 1.52 2.98 0.28 950.13 85.44
952 FC / Franklin Covey Co. Mga Serbisyo sa Pamamahala 247.02 38.85 27.27 33.66 19.56 72.44 85.43
955 COO / The Cooper Companies, Inc.
The Cooper Companies, Inc., based in the United States, operates primarily in the global medical device sector. As a leading entity in this industry, it primarily focuses on two core business units: CooperVision and CooperSurgical. CooperVision is a significant manufacturer of contact lenses, offering products that address conditions such as myopia and astigmatism, along with providing solutions in multifocal and toric lenses. Meanwhile, CooperSurgical is dedicated to women’s health, delivering medical devices, and fertility solutions that aid healthcare professionals across a range of gynecological and obstetric applications. Together, these divisions embody The Cooper Companies’ commitment to advancing healthcare through innovative and specialized products.
Ophthalmic Goods 13,480.00 110.25 84.84 95.77 67.40 42.09 85.42
956 ATNM / Actinium Pharmaceuticals, Inc.
Actinium Pharmaceuticals, Inc., based in the United States, operates within the biopharmaceutical industry and focuses on developing targeted therapies for cancers with high unmet needs. The company's principal projects center on its proprietary Antibody Radiation Conjugates (ARCs) technology, which innovatively combines the targeting ability of antibodies with the cell-killing power of radiation. A notable project is Iomab-B, an ARC intended for bone marrow transplant conditioning, currently in a pivotal Phase 3 clinical trial. Additionally, Actimab-A, another lead ARC product, targets CD33 in Acute Myeloid Leukemia (AML) and is in Phase 1/2 clinical trials. These projects exemplify the company's dedication to advancing novel treatment options for challenging oncological indications.
Mga Paghahanda sa Parmasyutiko 55.53 9.45 2.02 5.10 1.78 183.33 85.42
958 PMN / ProMIS Neurosciences, Inc.
ProMIS Neurosciences, Inc., based in Canada, operates principally in the biotechnology sector, focusing on discovering and developing precision medicine therapeutics aimed at effectively treating neurodegenerative diseases, particularly Alzheimer’s disease and amyotrophic lateral sclerosis (ALS). Leveraging its proprietary discovery platform, ProMIS is adept at identifying novel therapeutic targets and generating antibodies specifically tailored to these targets. Key projects include its advanced antibody Therapeutics for Alzheimer’s disease, which focus on misfolded strains of Amyloid beta, a pivotal pathological marker of the disease. Furthermore, their extended portfolio explores potential treatments for other neurodegenerative diseases, demonstrating ProMIS Neurosciences' commitment to addressing critical unmet medical needs within the neurological disease domain.
Mga Paghahanda sa Parmasyutiko 17.65 9.98 3.03 5.74 0.54 962.70 85.41
959 ESPR / Esperion Therapeutics, Inc.
Esperion Therapeutics, Inc., based in the United States, is a prominent player in the biopharmaceutical industry, focusing on the development and commercialization of therapies to treat elevated low-density lipoprotein cholesterol (LDL-C), commonly known as bad cholesterol. The company has carved a niche in cardiovascular drug development, with its flagship products being Nexletol and Nexlizet. These novel therapies are designed as adjuncts to diet and statin therapy for individuals who still struggle to reach LDL-C goals. Esperion Therapeutics emphasizes innovation in lipid management to address unmet medical needs in the cardiovascular health sector, seeking to improve outcomes for patients with elevated cholesterol levels who are at heightened risk of cardiovascular diseases.
Mga Paghahanda sa Parmasyutiko 444.34 16.80 1.62 5.92 2.22 166.49 85.41
962 RCEL / AVITA Medical, Inc.
AVITA Medical, Inc., based in Valencia, California, USA, operates in the biotechnology industry, primarily focusing on regenerative medicine and skin repair. The company is renowned for its proprietary technology platform, RECELL, which facilitates the rapid creation of autologous skin cells to treat a variety of skin issues, including burns, chronic wounds, and aesthetic imperfections. AVITA's key projects revolve around expanding the therapeutic applications of the RECELL system and streamlining the treatment protocols for burn care, which has pivotal implications for significantly reducing hospital stays and improving patient recovery outcomes. The company strategically focuses on clinical research and collaborations to improve and validate its regenerative product offerings on a global scale.
Mga Instrumento at Apparatus ng Surgical at Medikal 115.37 19.95 3.03 11.42 4.34 163.53 85.40
964 OSTX / OS Therapies Incorporated Mga Paghahanda sa Parmasyutiko 70.90 21.00 6.06 13.77 2.39 483.47 85.39
965 APLT / Applied Therapeutics, Inc.
Applied Therapeutics, Inc., based in the United States, is a biopharmaceutical company focused primarily on the development of novel treatments in the areas of metabolic and cardiorenal diseases. A significant endeavor for the company involves the advanced clinical development of its flagship drug candidate, AT-007, a central nervous system penetrant aldose reductase inhibitor, designed for the treatment of Galactosemia, a rare pediatric metabolic disease. Applied Therapeutic's innovative therapeutic approach also extends to addressing diabetic complications and other rare diseases through a pipeline fashioned to disrupt existing treatment paradigms. The company operates at the forefront of addressing unmet medical needs by advancing its proprietary technology and through rigorous clinical trials to prove efficacy and safety of its products.
Mga Paghahanda sa Parmasyutiko 69.93 5.25 1.52 2.93 0.49 485.45 85.38
967 ALKT / Alkami Technology, Inc. Naka-prepack na Software 2,663.49 48.30 29.29 39.02 25.60 52.46 85.38
968 KOS / Kosmos Energy Ltd.
Kosmos Energy Ltd. is an independent oil and gas exploration and production company headquartered in Dallas, Texas, USA. Founded in 2003, the company primarily operates in the exploration, development, and production of oil and natural gas in deepwater offshore environments. Key regions of operation include the Gulf of Mexico and the Atlantic Margins, with significant projects like the Jubilee Field in Ghana and the Greater Tortue Ahmeyim project on the maritime border of Mauritania and Senegal. Kosmos Energy is known for its focus on frontier and emerging areas, utilizing high-impact exploration techniques and sustainable practices to develop hydrocarbon resources while aiming to reduce environmental impact.
Crude Petroleum at Natural Gas 856.01 8.92 2.22 4.95 1.79 176.77 85.38
972 ACHC / Acadia Healthcare Company, Inc.
Acadia Healthcare Company, Inc., based in the United States, operates as a leading provider in the behavioral healthcare industry. The company specializes in delivering psychiatric and chemical dependency services through a network extending to over 220 facilities across the United States and Puerto Rico. Acadia’s services are comprehensive, encompassing inpatient psychiatric hospitals, specialty treatment facilities, residential treatment centers, and outpatient clinics. Acadia Healthcare focuses on creating tailored treatment programs that address a wide spectrum of mental health conditions and substance abuse issues, striving to meet the diverse needs of its patient population. Through strategic acquisitions and expansions, Acadia significantly enhances its service portfolio, emphasizing the development of innovative treatment modalities and accessibility to high-quality care.
Specialty Outpatient Facilities, Not Elsewhere Classified 2,075.44 57.75 20.20 32.13 22.96 39.94 85.36
978 HQY / HealthEquity, Inc.
HealthEquity, Inc., based in the United States, operates predominantly within the health care sector, specifically focusing on technology-driven services that facilitate health savings accounts (HSAs) and other health financial services. Since its inception, the company has expanded its offerings to include reimbursement accounts such as FSAs, HRAs, as well as VEBA, and commuter benefits. A key project for HealthEquity involves integrating technology to simplify the management and accessibility of health accounts for both employers and account holders, emphasizing user-friendly platforms and 24/7 customer service. The company has also been actively working on partnerships and acquisitions to broaden its service capabilities and market reach, thereby consolidating its position as a leader in health account solutions in the U.S.
Mga Serbisyo sa Negosyo, Hindi Nauuri sa Ibang Lugar 7,746.16 136.50 105.04 124.28 89.33 39.13 85.34
980 MRKR / Marker Therapeutics, Inc.
Marker Therapeutics, Inc., based in the United States, operates within the biotechnology sector, primarily focusing on the development of innovative cellular immunotherapies for cancer. The company is dedicated to advancing T cell-based therapies with enhanced efficacy and safety profiles compared to existing alternatives. A key project involves multi-tumor-associated antigen-specific T cells (MultiTAA), which are designed to target multiple antigens, potentially improving the effectiveness and reducing the likelihood of tumor escape. Additionally, Marker is progressing with several clinical trials aimed at treating various cancers, including pancreatic, acute myeloid leukemia, and other malignancies, showcasing their commitment to broadening the scope of effective treatments in the oncology field. These efforts highlight Marker's role in pioneering next-generation treatments that could significantly impact cancer therapy.
Mga Paghahanda sa Parmasyutiko 10.47 13.12 4.04 8.33 0.93 792.44 85.34
981 ATOS / Atossa Therapeutics, Inc.
Atossa Therapeutics, Inc., based in the United States, is a clinical-stage biopharmaceutical company focused on developing innovative therapies in oncology and infectious diseases. Notably, the company has concentrated its efforts on breast cancer treatments and other significant unmet medical needs. A prominent project includes the development of Endoxifen, an oral formulation designed to reduce mammographic breast density and treat breast cancer. Additionally, Atossa is exploring novel therapeutic options for severe COVID-19, aiming to enhance the healthcare community's ability to combat this and potentially future pandemics. The company's strategic initiatives are geared towards advancing their proprietary therapeutics from concept through clinical development, with an emphasis on addressing critical treatment gaps in global health.
Mga Paghahanda sa Parmasyutiko 98.70 7.88 4.04 5.74 0.76 650.88 85.34
983 BYRN / Byrna Technologies Inc. Miscellaneous Electrical Machinery, Equipment, and Supplies 462.64 48.30 35.35 39.27 20.40 92.50 85.33
986 ALXO / ALX Oncology Holdings Inc. Mga Paghahanda sa Parmasyutiko 61.53 3.15 1.01 2.30 1.17 99.57 85.32
989 IRDM / Iridium Communications Inc.
Iridium Communications Inc., based in McLean, Virginia, USA, operates within the telecommunications sector, primarily focusing on satellite communications. Renowned for its Iridium satellite constellation, the company provides voice and data coverage to satellite phones, pagers, and integrated transceivers over the Earth’s entire surface. Iridium serves both military and civilian sectors and is pivotal for its global communication services which are vital in remote areas where traditional networks cannot reach. Key projects include the Iridium NEXT satellite project, an ambitious initiative to replace its original satellites with more technologically advanced models, enhancing the company’s offer in terms of functionality and reliability while supporting emerging technologies like IoT connectivity. This strategic upgrade underlines Iridium's commitment to maintaining its position as a leader in global communications innovation.
Communications Equipment, Not Elsewhere Classified 2,649.19 47.25 25.25 36.85 24.89 47.98 85.30
999 VOYG / Voyager Technologies, Inc. 914.02 52.50 45.45 49.47 30.69 60.72 85.25
1001 APRE / Aprea Therapeutics, Inc. Mga Paghahanda sa Parmasyutiko 9.00 11.55 10.10 10.71 1.56 584.35 85.24
1002 RNXT / RenovoRx, Inc. Mga Paghahanda sa Parmasyutiko 35.82 12.08 3.03 5.61 0.96 473.91 85.24
1005 IAS / Integral Ad Science Holding Corp. Computer Programming, Pagproseso ng Data, At Iba Pang Serbisyong Kaugnay ng Computer 1,484.98 18.90 9.09 13.26 8.99 47.63 85.22
1012 NPWR / NET Power Inc. Electrical Industrial Apparatus 198.59 7.35 2.02 5.10 2.55 100.00 85.20
1014 SDST / Stardust Power Inc. 33.93 6.30 1.41 3.16 0.40 685.39 85.19
1015 VNOM / Viper Energy, Inc. Crude Petroleum at Natural Gas 5,222.37 71.40 45.45 54.54 39.84 36.89 85.19
1022 TZOO / Travelzoo Advertising 109.23 33.60 17.17 25.50 9.81 160.04 85.15
1023 OMER / Omeros Corporation
Omeros Corporation, based in the United States, is a biopharmaceutical company known for its innovative approaches in the development and commercialization of drugs targeting inflammation, coagulopathies, and disorders of the central nervous system. Key projects include OMS721, a lectin pathway inhibitor, used for the treatment of atypical hemolytic-uremic syndrome (aHUS) and IgA nephropathy. Omeros has also made headlines with its Omidria product, a mydriatic and anti-inflammatory used during cataract surgery or intraocular lens replacement, which enhances surgical outcomes by preventing pupil constriction and reducing postoperative pain. The company's strategic focus on novel therapeutic agents addressing critical unmet needs in the medical field marks its significant footprint in the healthcare industry.
Mga Paghahanda sa Parmasyutiko 249.99 47.25 9.09 30.60 4.16 634.69 85.15
1031 COTY / Coty Inc.
Coty Inc., headquartered in the United States, operates primarily within the global beauty industry. As a notable player, it develops, manufactures, and markets beauty products in several categories including fragrances, cosmetics, and skin and body care. Coty’s portfolio boasts a mix of licensed brands as well as owned global labels, allowing it to harness a diverse range of market segments. Its strategic initiatives have focused on expanding digital and direct-to-consumer channels, revitalizing core brands, and leveraging innovations. Coty’s insistence on sustainability has further directed numerous projects aimed at reducing environmental impact, underpinning its commitment to eco-friendly practices while catering to a broad, evolving consumer base.
Mga Pabango, Kosmetiko, at Iba Pang Paghahanda sa Toilet 3,733.44 14.18 4.04 6.92 4.28 61.85 85.10
1032 VERU / Veru Inc. Mga Paghahanda sa Parmasyutiko 47.91 31.50 10.10 21.68 3.25 562.84 85.09
1037 GUTS / Fractyl Health, Inc. Mga Instrumento at Apparatus ng Surgical at Medikal 48.48 10.50 4.04 6.80 0.97 600.17 85.06
1038 BTBT / Bit Digital, Inc. Mga Serbisyo sa Pananalapi 728.59 7.35 5.05 5.78 2.57 125.34 85.05
1039 CLYM / Climb Bio, Inc. Mga Paghahanda sa Parmasyutiko 151.11 10.50 7.07 9.18 2.23 308.91 85.04
1040 OPRA / Opera Limited - Depositary Receipt (Common Stock)
Opera Limited is a global internet company based out of Oslo, Norway that specializes primarily in web browsers, fintech, and other technology services. Established in 1995, Opera has developed into a significant player in the tech sector by offering an array of products including its Opera web browser, which is renowned for its speed and efficiency on various digital platforms. The company has also ventured into the fintech industry with Opera Pay, expanding its analytical capabilities and user engagement strategies. Opera Limited continues to innovate by focusing on new technology integrations and expanding its market reach, placing a strong emphasis on user privacy and data security in its software and applications.
Naka-prepack na Software 1,456.38 34.65 23.23 26.30 16.25 61.85 85.04
1041 KIDS / OrthoPediatrics Corp.
OrthoPediatrics Corp., based in the United States, specializes in the orthopedic sector of the healthcare industry, focusing specifically on developing and providing medical devices that cater to the unique musculoskeletal needs of children. Since its establishment, it has demonstrated a strong commitment to pediatric orthopedics, a field that addresses conditions ranging from trauma to congenital disorders and deformities. Key projects of the company include an extensive portfolio of implants and instruments specifically designed for pediatric patients. These offerings are underscored by a dedication to innovation, particularly through the development of proprietary systems designed to improve surgical outcomes and overall quality of life for its young patients. As it grows, OrthoPediatrics continues to expand its global reach, impacting pediatric orthopedic care on an international scale.
Mga Instrumento at Apparatus ng Surgical at Medikal 535.55 44.10 22.22 34.53 21.36 61.68 85.02
1052 PACB / Pacific Biosciences of California, Inc.
Pacific Biosciences of California, Inc., based in the United States, operates in the biotechnology sector, primarily focusing on the development and manufacture of advanced sequencing technologies. The company's innovative approach centers on its sophisticated Single Molecule, Real-Time (SMRT) technology, which enhances the accuracy and speed of genetic analysis. This technology underpins major projects aimed at genomic sequencing, complex population genomics, and cancer research. Pacific Biosciences' efforts are instrumental in advancing our understanding of genetic materials, which has significant implications for personalized medicine, disease research, and agricultural development. The company's dedication to cutting-edge research and development continually sets new standards in the genomic sequencing industry.
Mga Instrumentong Analitikal sa Laboratory 390.45 3.15 1.01 2.02 1.31 55.18 84.99
1056 LB / LandBridge Company LLC 1,337.01 123.90 55.55 79.22 53.15 49.05 84.97
1058 COCH / Envoy Medical, Inc. Mga Orthopedic, Prosthetic, at Surgical Appliances at Supplies 26.69 9.98 5.05 7.01 1.23 465.52 84.96
1068 PR / Permian Resources Corporation
Permian Resources Corporation, based in the United States, operates within the energy sector, primarily focusing on oil and natural gas exploration and production. As suggested by its name, the company’s core operations are centered in the Permian Basin, a prolific oil-rich region that spans parts of Texas and New Mexico. Permian Resources engages in the acquisition, development, and exploration of oil and natural gas properties, leveraging advanced technology and practices to enhance recovery and efficiency in resource extraction. Key projects involve not only exploiting existing hydrocarbon reservoirs but also improving techniques in hydraulic fracturing and horizontal drilling, ensuring substantial production growth and reserve replacement. The firm is committed to operational excellence and sustainable practices, promoting cost-effective and environmentally responsible methodologies.
Crude Petroleum at Natural Gas 10,021.24 24.15 14.14 19.00 14.29 32.85 84.91
1071 FINV / FinVolution Group - Depositary Receipt (Common Stock)
FinVolution Group, based in China, primarily operates in the financial technology sector, focusing on online consumer finance through its technological platform. The company offers a range of financial products and services aimed at harnessing the power of advanced fintech and digital capabilities to serve underbanked populations. Key projects include facilitating borrower-lender interactions via an automated and efficient online platform, leveraging big data and analytics to optimize credit decisions, and enhancing user experience through technological innovations. By providing accessible financial services, FinVolution Group aims to address the credit needs of individuals and SMEs, driving financial inclusion in diverse markets across China and Southeast Asia.
Loan Brokers 2,112.06 13.86 10.30 12.07 8.25 46.24 84.87
1076 NAGE / Niagen Bioscience, Inc.
ChromaDex Corporation is an American company, based primarily in Los Angeles, California. Operating within the nutraceutical industry, ChromaDex focuses on the discovery, acquisition, development, and commercialization of proprietary, science-based ingredient technologies. The company’s primary project and flagship product is Niagen, a novel form of vitamin B3 known as nicotinamide riboside, which has been clinically proven to increase nicotinamide adenine dinucleotide (NAD) levels, essential for cellular metabolism and energy production. ChromaDex maintains a strong commitment to scientific validation, which has facilitated collaborations and research partnerships with prestigious universities and research institutions, helping to bolster its credibility and market presence in the dietary supplement landscape.
Bahan Kimia Obat dan Produk Botani 789.55 24.15 11.31 16.36 9.90 65.26 84.86
1078 DBRG / DigitalBridge Group, Inc.
DigitalBridge Group, Inc., headquartered in the United States, operates primarily within the digital infrastructure sector. The company focuses on investing in, building, and operating critical infrastructure necessary for the digital age, including data centers, cellular towers, fiber networks, and small cells. DigitalBridge transitions from a diversified real estate investment trust to a specialized digital infrastructure firm, marking its strategic pivot towards technology-driven properties. Key projects frequently involve large-scale developments in data center operations, enhancements in telecommunications infrastructure, and expansions into emerging markets. This shift underlines DigitalHygienicBridge's commitment to supporting the expansive demands of data transmission and storage, internet connectivity, and mobile communication technologies globally.
Payo sa Pamumuhunan 1,974.60 21.00 11.11 17.08 11.41 49.74 84.85
1085 FIVN / Five9, Inc.
Five9, Inc. is a United States-based company that specializes in cloud software for contact centers. Operating in the technology sector, it provides businesses with scalable cloud-based solutions to manage customer interactions across various channels including voice, chat, email, and social media. The company's innovative approach focuses on enhancing customer service capabilities while streamulating operational efficiency. Key projects typically involve the development and implementation of advanced artificial intelligence and machine learning technologies to automate and optimize customer engagement and workflow processes. Five9's solutions support a global clientele, empowering organizations to improve customer satisfaction, increase operational effectiveness, and drive sales growth efficiently within their customer service departments.
Mga Serbisyo sa Pagproseso ng Computer at Paghahanda at Pagproseso ng Data 2,077.59 61.95 28.28 36.31 26.92 35.03 84.83
1087 PYPD / PolyPid Ltd. Mga Instrumento at Apparatus ng Surgical at Medikal 52.44 14.70 10.10 12.75 3.39 280.60 84.82
1089 SCYX / SCYNEXIS, Inc.
SCYNEXIS, Inc., based in the United States, operates within the biotechnology industry, focusing on the development and commercialization of innovative therapies to address unmet medical needs. The company's key project is its flagship product, ibrexafungerp, a novel antifungal agent from a new class of structurally distinct glucan synthase inhibitors, designed to treat a variety of fungal infections including candidiasis and invasive aspergillosis. Ibrexafungerp is noteworthy for its oral and intravenous formulations, aiming to provide significant advantages over existing antifungal therapies. SCYNEXIS's strategic initiatives involve advancing this compound through clinical trials, securing regulatory approvals, and exploring its potential across multiple infectious disease indications to meet pressing healthcare challenges.
Mga Paghahanda sa Parmasyutiko 32.91 6.30 4.04 4.76 0.83 466.67 84.82
1095 KELYA / Kelly Services, Inc.
Kelly Services, Inc., headquartered in the United States, operates as a global workforce solutions provider specializing in the staffing sector. The firm caters to a broad spectrum of industries, including administrative, industrial, technology, and more. Kelly Services is known for pioneering temporary staffing services in the U.S., evolving into a comprehensive provider of both temporary and permanent placement. Key initiatives have broadened to include outsourcing and consulting services tailored to enhance operational efficiency and workforce flexibility for their clients. The company places significant emphasis on evolving workforce demands, utilizing technology to develop innovative staffing and workforce management solutions, thus aligning with shifts in the global labor market.
Help Supply Services 500.87 28.35 25.25 26.52 14.23 86.43 84.79
1096 IOBT / IO Biotech, Inc. Mga Paghahanda sa Parmasyutiko 104.09 14.70 4.04 9.18 1.58 481.01 84.77
1099 YUMC / Yum China Holdings, Inc. Mga Restaurant, Kainan, at Lugar ng Kainan 16,680.56 76.23 53.63 59.19 44.72 32.36 84.75
1104 OKTA / Okta, Inc.
Okta, Inc., based in the United States, operates primarily within the technology sector, specializing in identity and access management services. The company offers cloud software that helps businesses secure user authentication into applications and facilitates developers in building identity controls into applications, website web services, and devices. Notably, Okta's solutions are widely recognized for supporting secure connections between people and technology through products like Single Sign-On, Multi-factor Authentication, Lifecycle Management, and more. As a key player within its industry, Okta is significant for driving innovations in cybersecurity, addressing complex challenges faced in protecting enterprise data across numerous applications and devices. Their projects often aim at simplifying and strengthening access security, reflecting a commitment to integrating cutting-edge technology with user-friendly security practices.
Naka-prepack na Software 16,277.42 155.40 75.75 122.45 92.77 31.96 84.72
1106 MTDR / Matador Resources Company
Matador Resources Company, based in the United States, is primarily engaged in the oil and natural gas sector, focusing on exploration, development, and production. Established in 2003 and headquartered in Dallas, Texas, the company possesses significant operational presence in the Delaware Basin portion of the Permian Basin, which spans West Texas and southeastern New Mexico. Within this region, Matador Resources has successfully developed key projects that leverage both resource-rich reserves and advanced horizontal drilling technologies. These initiatives underscore its commitment to optimizing resource extraction while maintaining environmental and safety standards. Through strategic asset development and management, Matador Resources seeks to enhance shareholder value while ensuring sustainable operational practices.
Crude Petroleum at Natural Gas 6,253.54 93.45 49.49 67.32 50.36 33.65 84.72
1112 ANVS / Annovis Bio, Inc.
Annovis Bio is a clinical-stage, drug platform company addressing neurodegeneration, such as Alzheimer's disease (AD), Parkinson's disease (PD) and Alzheimer's in Down Syndrome (AD-DS).
Mga Paghahanda sa Parmasyutiko 45.01 21.00 8.08 14.54 2.31 529.22 84.68
1114 CNTB / Connect Biopharma Holdings Limited - Depositary Receipt (Common Stock) Mga Paghahanda sa Parmasyutiko 113.94 7.88 6.06 6.97 2.06 240.00 84.67
1116 PAR / PAR Technology Corporation
PAR Technology Corporation, headquartered in the United States, operates predominantly in the global hospitality and government sectors. Specializing in systems and service solutions, the company's main activities include providing point-of-sale (POS) software, hardware, and service integrations tailored primarily for restaurants and retail outlets. A significant aspect of PAR Technology's business is also dedicated to offering intelligence, surveillance, and reconnaissance (ISR) solutions through its subsidiary, PAR Government. Key projects have emphasized the development and enhancement of advanced POS systems, such as Brink POS software and EverServ hardware, designed to optimize restaurant operations and improve customer engagement through technology-driven services. These innovations reflect PAR's commitment to integrating cutting-edge technology within the hospitality industry to streamline operations and enhance user experiences.
Calculating and Accounting Machines, Except Electronic Computers 2,076.92 101.85 50.50 77.52 51.18 51.58 84.66
1117 WEAV / Weave Communications, Inc. Naka-prepack na Software 598.23 15.75 9.09 12.46 7.78 59.93 84.66
1121 SGRY / Surgery Partners, Inc.
Surgery Partners, Inc., based in the United States, operates within the healthcare sector, primarily focusing on providing surgical services. As a leading operator of surgical facilities, the company’s business model revolves around the development and management of ambulatory surgery centers (ASCs) in partnership with physicians. Key projects include expanding its network of multi-specialty facilities to improve accessibility and efficiency in outpatient surgical care. Surgery Partners is dedicated to enhancing patient outcomes and driving innovation through partnerships and by leveraging advanced technology to maximize operational efficiencies. This strategy not only supports high-quality patient care but also underscores its commitment to cost-effective healthcare solutions, positioning the company for sustained growth in the competitive medical services market.
Pangkalahatang Medikal at Surgical na mga Ospital 2,888.97 37.80 24.24 31.99 22.69 40.99 84.61
1124 NOA / North American Construction Group Ltd.
North American Construction Group Ltd., based in Canada, operates primarily in the heavy construction and mining industries. Renowned for its large-scale excavation and development projects, the company primarily serves the Canadian oil sands and resource extraction sectors. With a robust fleet of heavy equipment, North American Construction Group Ltd. is instrumental in major construction and mining tasks, including earthmoving, site preparation, and road building. Key projects typically involve collaborations with leading energy corporations, emphasizing the development and maintenance of oil sand sites. The company stands out for its comprehensive project management capabilities, which extend from planning and environmental solutions to the actual execution of construction and operational tasks.
Mga Serbisyo sa Larangan ng Langis at Gas, Hindi Nauuri sa Ibang Lugar 399.00 34.07 13.84 22.38 13.67 63.61 84.61
1128 COLD / Americold Realty Trust, Inc.
Americold Realty Trust, Inc., based in the United States, operates within the real estate sector, specifically focusing on temperature-controlled warehouses and supply chain management. The company provides essential infrastructure for the global cold chain, catering to a diverse clientele including food producers, processors, distributors, and retailers. Americold’s facilities are integral to the storage and transportation of perishable goods, optimizing the distribution of food commodities under controlled temperatures. Key projects have included strategic acquisitions and technology-driven enhancements to expand its operational capacity and efficiency, positioning Americold as a leader in refrigerated warehousing and logistics. As of 2023, the company holds a significant footprint in this niche market, supporting its status as a vital component of food supply chain resilience worldwide.
Mga Trust sa Pamumuhunan sa Real Estate 4,111.72 25.20 17.17 20.64 14.44 42.95 84.58
1131 WALD / Waldencast plc Mga Pabango, Kosmetiko, at Iba Pang Paghahanda sa Toilet 5.25 2.02 3.57 1.56 128.12 84.57
1139 MAT / Mattel, Inc.
Mattel, Inc., based in the United States, is a dominant player in the global toy manufacturing industry. The company is renowned for creating a diverse portfolio of iconic brands and products, including Barbie, Hot Wheels, Fisher-Price, and American Girl. Mattel’s strategic approach focuses on innovative product design, expansive distribution networks, and engaging multimedia content to enhance brand loyalty and drive growth. Key projects revolve around digital transformation, including the incorporation of augmented reality in toy experiences, and the expansion into entertainment sectors with film and television adaptations of their popular toy lines. These initiatives align with the company's objectives to leverage technological advancements and capture broader audience segments, ensuring long-term competitiveness in the dynamic toy market.
Mga Manika at Stuffed Toys 5,920.05 31.50 21.21 25.44 18.30 38.99 84.53
1148 SBC / SBC Medical Group Holdings Incorporated
SBC Medical Group Holdings Incorporated is a U.S.-based healthcare company specializing in integrated medical group services. The company operates a network of medical facilities that deliver comprehensive primary and specialty care, focusing on quality patient outcomes and efficient healthcare management.
419.10 6.82 6.56 6.63 4.08 63.10 84.49
1150 ZETA / Zeta Global Holdings Corp. Naka-prepack na Software 4,661.72 46.20 18.18 27.20 19.64 38.53 84.48
1151 MNTN / MNTN, Inc. Blangkong Check 818.86 40.95 25.25 34.34 20.41 68.33 84.48
1152 SRPT / Sarepta Therapeutics, Inc.
Sarepta Therapeutics, Inc., based in the United States, operates primarily in the biotechnology industry, focusing on the discovery and development of RNA-targeted therapeutics. The company specializes in genetic medicine, specifically designing treatments for rare diseases, notably Duchenne muscular dystrophy (DMD). Noteworthy projects include its advanced gene therapy pipeline and multiple marketed products aimed at addressing the underlying genetic causes of DMD. Their innovative approach leverages proprietary platforms for RNA-targeted therapies, enhancing their leadership in the field of genetic medicine. As such, Sarepta Therapeutics is at the forefront of developing potentially transformative treatments for patients with life-altering genetic diseases.
Mga Paghahanda sa Parmasyutiko 1,779.23 194.25 5.05 33.58 18.20 84.41 84.46
1155 RVTY / Revvity, Inc.
Revvity, Inc. is a US-based corporation focused primarily on the technology sector, particularly in the development and distribution of software and related services. The company has garnered attention for its innovative approach to cloud computing solutions and data analytics, positioning itself as a key player in digital transformation strategies for businesses of various scales. Revvity, Inc. also actively engages in research and development projects aimed at integrating artificial intelligence into their offering, enhancing user engagement and operational efficiency for their clients. Their strategic initiatives typically revolve around creating sustainable, advanced technology platforms that facilitate enterprise resource planning and customer relationship management, meeting the evolving needs of global markets.
Mga Instrumentong Analitikal sa Laboratory 10,591.35 194.25 90.90 123.07 90.11 36.56 84.45
1160 VCYT / Veracyte, Inc. Mga Medikal na Laboratoryo 2,377.61 55.65 28.28 42.05 30.34 38.63 84.44
1168 GOCO / GoHealth, Inc. Mga Ahente ng Insurance, Broker, at Serbisyo 57.19 26.25 16.16 21.62 5.11 324.00 84.40
1169 BRNS / Barinthus Biotherapeutics plc - Depositary Receipt (Common Stock)
Barinthus Biotherapeutics plc, based in the United Kingdom, operates primarily in the biotechnology sector, focusing on developing novel therapeutic solutions for severe medical conditions. The company is particularly renowned for its pioneering projects aimed at enhancing treatment modalities for autoimmune diseases and various types of cancers. Key projects include the development of innovative, targeted drug delivery systems and biologics that seek to improve efficacy and reduce side effects compared to traditional therapies. Barinthus Biotherapeutics has been instrumental in advancing research and clinical trials to address unmet medical needs, positioning itself as a leader in biotechnological innovations aimed at improving patient outcomes on a global scale.
Mga Paghahanda sa Parmasyutiko 45.19 6.30 3.03 4.59 1.12 309.82 84.40
1173 KDP / Keurig Dr Pepper Inc.
Keurig Dr Pepper Inc., based in the United States, operates within the beverage and food sector, primarily focusing on the manufacturing and distribution of non-alcoholic drinks. Notably renowned for its coffee and soft drink products, the company represents a merger between Keurig Green Mountain and Dr Pepper Snapple Group, creating a diversified portfolio encompassing coffee systems, single-serve beverages, and various flavored products. Keurig Dr Pepper continues to drive innovation and market expansion through strategic partnerships and product development, aligning with the growing market trends towards healthy and convenient beverage options. Key projects include sustainability initiatives aimed at reducing environmental impact and enhancing resource efficiency across their product line.
Mga inumin 39,516.25 46.20 34.34 39.54 29.09 36.00 84.39
1176 ASTH / Astrana Health, Inc. Mga Serbisyo sa Pagkonsulta sa Pamamahala 1,570.47 56.70 35.35 44.77 31.96 40.07 84.38
1179 GDYN / Grid Dynamics Holdings, Inc. Naka-prepack na Software 693.12 15.75 14.14 14.96 8.29 80.87 84.37
1182 INMB / INmune Bio, Inc. Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 54.10 22.05 2.02 8.57 2.03 321.03 84.36
1187 NNOX / Nano-X Imaging Ltd. X-Ray Apparatus at Tubes at Kaugnay na Irradiation Apparatus 247.13 10.50 7.07 8.42 3.87 117.72 84.35
1188 KLRS / Kalaris Therapeutics, Inc. 75.93 21.00 3.03 11.73 4.08 188.92 84.35
1190 OVV / Ovintiv Inc.
Ovintiv Inc., headquartered in Denver, Colorado, USA, operates primarily in the oil and gas industry, engaging in the exploration, development, and production of hydrocarbons. Originally known as Encana Corporation, the company rebranded to Ovintiv Inc. following a strategic shift and relocation from Canada to the United States. Ovintiv focuses on onshore operations, leveraging innovative technologies to enhance its hydrocarbon output and efficiency. Key projects include significant assets in the Permian Basin, the Montney formation, and the Anadarko Basin. These regions are rich in resources and pivotal to Ovintiv's production strategy, which emphasizes cost-effective extraction methods and sustainable practices to optimize both economic and environmental performance.
Crude Petroleum at Natural Gas 10,824.84 70.35 42.42 56.06 42.12 32.99 84.34
1193 FRGE / Forge Global Holdings, Inc. Security At Commodity Brokers, Dealers, Exchanges, At Serbisyo 233.76 63.00 30.30 39.27 18.85 109.22 84.32
1196 ARQT / Arcutis Biotherapeutics, Inc. Mga Paghahanda sa Parmasyutiko 1,859.26 30.45 19.19 23.20 15.52 49.52 84.28
1200 SPSC / SPS Commerce, Inc.
SPS Commerce, Inc. is headquartered in the United States and operates primarily in the field of cloud-based supply chain management software. Pioneering solutions within the retail sector, the company specializes in EDI technology, enhancing logistical efficiencies through streamlined communications between vendors and retailers. SPS Commerce offers a suite of scalable products including fulfillment, analytics, and sourcing which are designed to support omnichannel retail strategies and improve vendor collaboration. Critical to its project portfolio is the implementation of automated supply chain solutions that integrate seamlessly with numerous retail systems, aiming to improve transparency, reduce costs, and enhance overall supply chain velocity for a global clientele. Through strategic support and platform expertise, SPS Commerce continues to facilitate expansive partner networks that contribute robustly to the evolve-commerce industry landscape.
Naka-prepack na Software 4,178.47 194.82 121.20 158.23 110.30 43.62 84.25
1201 SERV / Serve Robotics Inc. 659.49 24.15 15.15 17.75 11.10 59.68 84.23
1206 SM / SM Energy Company Crude Petroleum at Natural Gas 3,272.82 61.95 27.27 40.88 28.55 43.10 84.21
1220 PTCT / PTC Therapeutics, Inc.
PTC Therapeutics, Inc. is a biopharmaceutical company based in the United States, specializing in the discovery, development, and commercialization of orally administered, proprietary small-molecule drugs. These drugs target post-transcriptional control mechanisms in orphan diseases, oncology, and infectious diseases. Among its key projects is the development of treatments for genetic disorders like Duchenne muscular dystrophy (DMD) through its drug Translarna™ (ataluren), which targets nonsense mutation genetic disorders. The company is also engaged in advancing a pipeline that includes gene therapy strategies for congenital disorders such as AADC deficiency. PTC Therapeutics employs a strategy that emphasizes both in-house research and strategic partnerships to drive drug development and commercialization.
Mga Paghahanda sa Parmasyutiko 3,915.72 123.90 44.44 67.93 49.33 37.71 84.11
1221 FULC / Fulcrum Therapeutics, Inc. Mga Paghahanda sa Parmasyutiko 350.51 15.75 5.05 11.29 6.48 74.54 84.11
1223 WAY / Waystar Holding Corp. 6,596.65 56.70 45.45 51.26 37.88 35.31 84.10
1229 EM / Smart Share Global Limited - Depositary Receipt (Common Stock) Mga Serbisyo sa Negosyo, Hindi Nauuri sa Ibang Lugar 2.85 2.74 2.76 1.32 109.41 84.04
1230 KD / Kyndryl Holdings, Inc.
Kyndryl Holdings, Inc., based in the United States, operates in the information technology services industry. Established as an independent entity following its spin-off from IBM in 2021, Kyndryl focuses on providing a broad array of IT services and solutions including cloud computing, data management, cybersecurity, and enterprise technology support to a global clientele. Key projects often involve complex IT modernization and digital transformation initiatives for large organizations, leveraging partnerships with major technology firms like Microsoft, VMware, and SAP. These collaborations aim to enhance Kyndryl’s delivery of advanced IT infrastructure and application management services, reinforcing its standing as a significant player in the IT services sector.
Computer Integrated Systems Design 7,318.06 57.75 40.40 47.54 31.79 49.61 84.04
1238 ENTA / Enanta Pharmaceuticals, Inc.
Enanta Pharmaceuticals, Inc., headquartered in the United States, focuses primarily on the research and development of small molecule drugs for the treatment of viral infections and liver diseases. Operating within the biotechnology sector, Enanta has concentrated its efforts on key therapeutic areas, notably hepatitis C virus (HCV) where it collaborates with Abbott Laboratories, and respiratory syncytial virus (RSV), as well as other liver diseases like non-alcoholic steatohepatitis (NASH). The company leverages its expertise in chemistry-driven drug discovery to develop innovative treatments that address significant unmet medical needs. As a part of its strategic initiatives, Enanta Pharmaceuticals continues to enhance its proprietary platforms to expand its pipeline and further its research endeavors across these core areas.
Mga Paghahanda sa Parmasyutiko 185.77 26.25 7.07 18.02 8.40 114.52 84.01
1241 ATRC / AtriCure, Inc. Mga Instrumento at Apparatus ng Surgical at Medikal 1,764.48 63.00 40.40 52.02 36.99 40.69 84.01
1248 ALGN / Align Technology, Inc.
Align Technology, Inc., based in the United States, operates primarily within the healthcare sector, focusing on manufacturing dental products. Renowned for creating Invisalign, an innovative transparent orthodontic device, Align Technology has profoundly impacted orthodontic practices globally. The company leverages advanced technology such as 3D printing and computer-aided design (CAD) to produce custom aligners tailored to individual dental structures. Aside from Invisalign, Align Technology also provides iTero dental scanning systems, which are integral in treatment planning and diagnostics in dentistry. These technological advancements underscore the company's commitment to enhancing dental care through continuous innovation and specialized products that cater to specific treatment needs in orthodontics and dentistry at large.
Mga Orthopedic, Prosthetic, at Surgical Appliances at Supplies 10,301.33 274.05 141.40 195.05 141.96 37.36 83.98
1256 UHAL.B / U-Haul Holding Company Automotive Rental At Leasing, Nang Walang Driver 10,347.23 118.44 65.27 83.79 52.24 60.42 83.92
1266 KRNT / Kornit Digital Ltd.
Kornit Digital Ltd. is an Israel-based company that specializes in the development, manufacturing, and marketing of industrial digital printing technologies for the garment, apparel, and textile industries. Operating globally, Kornit Digital provides comprehensive digital printing solutions, including printers, inks, consumables, and software designed for various textile applications. Key products include the company's innovative direct-to-garment printing systems and its patented NeoPigment ink technology, which simplifies the printing process and reduces environmental impact by eliminating the need for external process steps typically associated with traditional textile printing. These advances have positioned Kornit Digital as a leader in sustainable and versatile textile printing solutions, actively shaping industry standards and practices.
Printing Trades Machinery and Equipment 674.76 40.95 20.20 26.18 14.94 75.23 83.85
1267 GTLB / GitLab Inc. Naka-prepack na Software 7,927.96 89.25 45.45 62.59 48.02 30.34 83.85
1271 ET / Energy Transfer LP - Limited Partnership Paghahatid ng Natural Gas 60,825.67 26.25 20.20 23.19 17.72 30.81 83.84
1275 EEFT / Euronet Worldwide, Inc.
Euronet Worldwide, Inc., based in the United States, operates as a leading provider in the electronic payments industry. The company offers payment and transaction processing and distribution solutions to financial institutions, retailers, service providers, and individual consumers. Key divisions within Euronet include the EFT (Electronic Funds Transfer) segment, which facilitates ATM and POS transactions; the epay segment, which focuses on prepaid mobile and other electronic payment products; and the Money Transfer segment, responsible for global money remittance services across various networks. Euronet's projects typically involve expanding its ATM networks, strengthening mobile banking services, and enhancing digital transactions capabilities to ensure secure, efficient, and accessible financial services worldwide.
Functions Related to Depository Banking, Not Elsewhere Classified 4,005.52 152.25 111.10 130.27 93.19 39.70 83.82
1276 UDMY / Udemy, Inc. Mga Serbisyong Pang-edukasyon 1,026.07 12.60 9.09 10.53 6.86 53.11 83.81
1278 BTMD / biote Corp. Bahan Kimia Obat dan Produk Botani 108.79 8.40 3.54 5.51 3.44 60.21 83.80
1285 FENC / Fennec Pharmaceuticals Inc.
Fennec Pharmaceuticals Inc. is based in Canada and operates primarily in the biotechnology industry, specializing in the development of therapies that aim to treat cancer and related diseases. A key project of Fennec Pharmaceuticals has been the development of PEDMARK™, a sodium thiosulfate formulation designed to reduce the incidence of cisplatin-induced hearing loss in children and adults receiving platinum-based chemotherapy. PEDMARK™ has shown promise in clinical trials, receiving breakthrough therapy designation from regulatory authorities for its potential to address this significant side effect of cancer treatment. The company’s strategic focus on advancing treatments that contribute to oncology supportive care underlines its commitment to enhancing quality of life for cancer patients through innovative medical solutions.
Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 241.03 15.75 13.13 14.08 8.87 59.59 83.79
1287 SSTI / SoundThinking, Inc. Naka-prepack na Software 162.80 31.50 19.19 21.93 12.73 73.09 83.79
1288 CFLT / Confluent, Inc.
Confluent, Inc., originally an American company, operates primarily within the software industry, specializing in data streaming services based on Apache Kafka. As a key innovator in real-time data technology, Confluent facilitates the adoption of stream processing, enabling enterprises to access data as real-time streams. This capability supports enhanced decision-making and operations across various sectors. Among its main projects, Confluent develops and maintains Confluent Platform, a more robust and scalable enhancement of Apache Kafka designed to enable real-time data integration and processing at scale. Additionally, the company offers Confluent Cloud, a fully managed service that simplifies the deployment and scaling of data streams in cloud environments, effectively catering to growing demands for agility and performance in data management.
Naka-prepack na Software 6,832.34 42.00 20.20 25.91 19.86 30.42 83.78
1292 INOD / Innodata Inc.
Innodata Inc., based in the United States, operates within the information technology and services industry, particularly focusing on data engineering, enrichment, and extraction to support artificial intelligence and information services. The company leverages technology to transform, enrich, and monetize digital data for clients across various sectors, including media, publishing, and information services, aligning with broader trends in data-driven decision-making and digital transformation. Key projects frequently involve large-scale content digitization and enhancement, development of AI/ML algorithms for intricate data processing tasks, and consulting services aimed at digital content optimization. Through such initiatives, Innodata remains integral in helping businesses optimize their digital assets and strategically implement advanced technologies.
Mga Serbisyo sa Pagproseso ng Computer at Paghahanda at Pagproseso ng Data 1,209.47 78.75 55.55 65.69 37.98 72.95 83.76
1300 NDLS / Noodles & Company
Noodles & Company, based in the United States, operates within the fast-casual dining sector, specializing in international and American noodle dishes, as well as pasta, soups, and salads. Founded in 1995, the company has grown to establish a significant presence with hundreds of locations across the U.S. By focusing on providing high-quality, fresh ingredients, and customizable menu options, Noodles & Company caters to a diverse array of customer preferences, including vegetarian and gluten-sensitive options. The company has invested in key projects aimed at enhancing the customer experience through digital innovation, including the implementation of a robust online ordering system and a loyalty program, which have been crucial for adapting to increased off-premise dining trends in recent years.
Mga Restaurant, Kainan, at Lugar ng Kainan 32.78 3.15 2.02 2.55 0.71 259.15 83.73
1301 CHDN / Churchill Downs Incorporated
Churchill Downs Incorporated, based in the United States, operates primarily in the gaming and racing industry. Renowned for its flagship Churchill Downs racetrack, home of the Kentucky Derby, the company has significantly diversified its operations to include casino gaming, online wagering on races, and a network of off-track betting facilities. Churchill Downs has been actively expanding its reach within the gaming sector, acquiring several casino properties and investing in the development of new gaming facilities in strategic locations. Additionally, the company has bolstered its digital presence through platforms like TwinSpires, targeting growth in the burgeoning market of online sports betting and gaming. This strategic expansion underscores its commitment to leveraging technology and innovation within its core competencies in racing and gaming.
Karera, Kasama ang Track Operation 7,281.85 162.75 126.25 140.40 103.73 35.52 83.72
1303 CINT / CI&T Inc. 716.42 9.45 6.87 8.00 5.44 46.68 83.71
1304 CPA / Copa Holdings, S.A.
Copa Holdings, S.A. is a Panama-based airline holding company that operates through its subsidiaries, primarily Copa Airlines and Copa Airlines Colombia. The company provides passenger and cargo air transportation services across North, Central, and South America, and the Caribbean. Copa Airlines is known for its extensive route network through its hub in Panama City, leveraging the strategic location to connect various regions efficiently. It focuses on offering reliable and cost-efficient services, maintaining a strong presence in Latin American aviation.
Transportasyong Panghimpapawid, Naka-iskedyul 4,843.48 199.50 131.30 160.38 117.34 36.73 83.71
1305 TYGO / Tigo Energy, Inc. Mga Semiconductor at Mga Kaugnay na Device 85.96 6.30 3.03 4.72 1.40 241.85 83.70
1306 ASND / Ascendis Pharma A/S - Depositary Receipt (Common Stock)
Ascendis Pharma A/S is a biopharmaceutical company based in Denmark, primarily engaged in developing innovative therapies in the fields of endocrinology, oncology, and central nervous system disorders. The company employs its proprietary TransCon technology to create prodrugs that provide sustained release of active drugs, offering therapeutic benefits with less frequent dosing. Key projects include treatments for growth hormone deficiency and hypoparathyroidism, such as their flagship product, TransCon hGH, a once-weekly prodrug for growth hormone deficiency that has shown promise in clinical trials. Ascendis Pharma also has significant initiatives underway in developing treatments for achondroplasia and other rare diseases, positioning itself as a notable player in the global pharmaceutical landscape focused on addressing unmet medical needs.
Mga Paghahanda sa Parmasyutiko 11,770.57 322.35 205.03 254.17 194.27 30.83 83.70
1307 ASRT / Assertio Holdings, Inc. Mga Paghahanda sa Parmasyutiko 80.20 3.15 1.52 2.75 0.84 230.41 83.70
1308 MTSR / Metsera, Inc. 3,701.67 68.25 45.45 58.48 35.29 65.71 83.70
1312 DCGO / DocGo Inc. Health Services 151.52 4.20 1.62 3.14 1.56 102.35 83.68
1316 RDW / Redwire Corporation Mga May Gabay na Misil At Mga Sasakyan At Bahagi ng Kalawakan 1,270.35 29.40 10.10 18.42 8.91 106.93 83.66
1319 PSNL / Personalis, Inc.
Personalis, Inc. is a genomics-based precision medicine company headquartered in the United States. Founded in 2011, the company primarily serves the biopharmaceutical industry with a focus on providing advanced genomic sequencing and analytics. Key to its operations is the Personalis NeXT Platform, designed to offer comprehensive molecular data of cancer tissues, which is crucial for the development of personalized cancer vaccines and other targeted therapies. Personalis extends its expertise beyond oncology, supporting population sequencing projects and clinical trials globally. By integrating innovative technology and extensive genomic intelligence, Personalis, Inc. plays a pivotal role in the advancement of precision medicine, striving to enhance personalized treatment approaches across various diseases.
Mga Medikal na Laboratoryo 433.50 9.45 5.05 7.20 4.89 47.02 83.65
1323 HITI / High Tide Inc.
High Tide Inc., based in Canada, is a prominent player in the cannabis industry, primarily engaged in the retail sector. As a vertically integrated entity, the company focuses on the manufacturing and distribution of smoking accessories and cannabis lifestyle products. It has expanded its reach through both physical storefronts and digital platforms, operating a considerable number of branded retail locations across Canada. Key projects include the strategic acquisition of other cannabis retail chains and the expansion of its e-commerce presence to solidify its market position. High Tide Inc.'s approach emphasizes customer engagement and accessibility, positioning itself to capitalize on both domestic and international growth opportunities in the evolving cannabis market.
Mga Tindahan, Hindi Nauuri sa Ibang Lugar 291.73 6.47 5.12 5.73 3.60 59.13 83.64
1334 ODV / Osisko Development Corp.
Osisko Development Corp., based in Canada, is a prominent player in the mining sector, primarily focusing on the exploration and development of gold mining projects. As a strategic spinoff from Osisko Gold Royalties in 2020, the company leverages its expertise to foster substantial growth in its project portfolio. Key projects that highlight Osisko Development's ambitious strategy include the Cariboo Gold Project in British Columbia and the San Antonio Gold Project in Sonora, Mexico. These initiatives exemplify the company's commitment to expanding its mineral reserves and resources, underpinning its goal to become a leading North American gold producer. Through these endeavours, Osisko Development combines operational excellence with sustainable practices, aligning its growth trajectory with environmental stewardship and community engagement.
Pagmimina ng Ginto At Pilak 375.42 5.64 3.62 4.32 2.72 58.96 83.58
1336 MDCX / Medicus Pharma Ltd.
Medicus Pharma Ltd. is a pharmaceutical company based in the United Kingdom, primarily engaged in the development and manufacturing of generic and proprietary pharmaceuticals. A significant portion of its operations is directed towards the research and development of innovative drug delivery systems, aimed at enhancing the efficacy and safety of existing medicinal compounds. Key projects have included the development of extended-release formulations for cardiovascular drugs, as well as partnerships aimed at tackling prevalent chronic conditions such as diabetes and arthritis. Medicus Pharma has garnered attention for its commitment to high manufacturing standards and its strategic collaborations with both global and regional distributors to expand its market reach, thereby strengthening its position in the competitive pharmaceutical industry.
30.96 28.35 12.12 20.06 1.94 932.43 83.57
1340 KMX / CarMax, Inc.
CarMax, Inc., based in the United States, primarily operates in the automotive retail industry and is recognized as the nation's largest retailer of used vehicles. The company's business model focuses on offering a broad range of used cars, which are sold through a combination of physical superstores and digital platforms, providing consumers with a seamless and user-friendly car-buying experience. Core to CarMax's operation is its unique auto-financing segment, which facilitates consumer sales by providing potentially customizable financing options. Noteworthily, CarMax has been expanding its digital capabilities, integrating online sales mechanisms with its nationwide network of stores, aiming to enhance accessibility and customer satisfaction in the used car market. This strategic alignment emphasizes technology-driven growth and customer-centric service delivery, underpinning its key projects and overall market strategy.
Mga Dealer ng Sasakyan At Mga Istasyon ng Serbisyo ng Gasolina 9,238.22 128.24 52.52 83.58 61.35 36.23 83.55
1346 OPCH / Option Care Health, Inc.
Option Care Health, Inc., based in the United States, operates in the healthcare sector, primarily focusing on providing home and alternate site infusion services. As the largest independent provider in the U.S., the company manages a broad range of treatments including anti-infectives, nutrition support, heart failure therapies, chronic inflammatory disorders treatments, and other high-tech infusion therapies. Their comprehensive services span infusion suites and home-based care, catering not only to patient needs but also striving to reduce hospitalization costs and improve patient outcomes through individualized care plans. Key projects by Option Care Health typically involve expanding their therapy lines and enhancing digital platforms to improve service delivery and patient engagement, reflecting their commitment to innovation in healthcare solutions.
Home Health Care Services 4,652.96 42.00 34.34 39.27 28.68 36.97 83.51
1352 XPOF / Xponential Fitness, Inc. Sari-saring Libangan At Libangan 295.04 22.05 9.09 12.58 8.41 49.41 83.46
1360 ESTC / Elastic N.V.
Elastic N.V., based in the Netherlands, operates in the software industry, primarily focusing on search and data analysis tools that aid businesses in data exploration in real-time. Elastic is renowned for its Elastic Stack, a suite of software applications that include Elasticsearch, Logstash, and Kibana, frequently utilized for their powerful search capabilities, operational intelligence, and analytics. The company serves a diverse range of industries including financial services, public sector, healthcare, and retail, underpinning critical processes in data search, logging, security, and analytics. Key projects often involve enhancements to their proprietary software, expansion of machine learning capabilities, and broadening their enterprise-grade offerings to support large-scale deployments and real-time analytics solutions.
Naka-prepack na Software 9,039.17 147.00 75.75 110.30 85.06 29.49 83.43
1361 SDGR / Schrödinger, Inc.
Schrödinger, Inc., based in the United States, operates within the biotechnology and software industries, focusing on computational chemistry to accelerate drug discovery and materials design. The company leverages its advanced molecular simulations platform to provide both software products and research services. This technological framework helps in identifying novel molecules with desirable therapeutic properties, thus streamlining the prediction and modeling of molecular behaviors effectively. Schrödinger's significant partnerships and collaborations with leading pharmaceutical entities exemplify its integral role in enhancing the efficiency of drug development processes. These collaborative efforts aim to bring more effective therapeutic solutions swiftly to market, clearly underlining Schrödinger’s pivotal contribution to both technology and healthcare sectors.
Mga Paghahanda sa Parmasyutiko 1,435.65 34.65 19.19 27.85 19.51 42.51 83.42
1362 WDAY / Workday, Inc.
Workday, Inc., headquartered in the United States, operates in the field of enterprise cloud applications for finance and human resources. The company delivers financial management, human capital management, planning, and analytics applications designed for the world’s largest organizations, educational institutions, and government agencies. Notable for its innovative use of machine learning and artificial intelligence in application development, a key project for Workday includes the continuing expansion of its Workday Cloud Platform, which allows customers and third-party developers to create custom applications within its core system architecture. By providing comprehensive suites that optimize business operations and enhance decision-making capabilities, Workday plays a crucial role in digital transformations within global enterprises.
Mga Serbisyo sa Pagproseso ng Computer at Paghahanda at Pagproseso ng Data 61,639.62 357.00 237.35 298.37 230.82 29.24 83.42
1363 IMNN / Imunon, Inc.
Imunon, Inc., based in the United States, operates chiefly in the biotechnology sector, focusing on the development of novel immunotherapy treatments. The company is particularly centered on innovating therapies that engage and modulate the immune system to combat cancer and autoimmune diseases, among other serious health challenges. A key undertaking of Imunon involves the advancement of its leading candidate, UV1, a peptide-based vaccine aimed at melanoma, a type of skin cancer. This vaccine is in clinical testing and represents a significant part of the company's efforts to enhance oncological treatment outcomes through immune system activation, showcasing Imunon's commitment to pioneering in the therapeutic landscape.
Mga Paghahanda sa Parmasyutiko 11.85 191.74 21.21 109.14 5.93 1,719.03 83.41
1364 CARR / Carrier Global Corporation
Carrier Global Corporation is an American multinational corporation headquartered in Palm Beach Gardens, Florida. As a leader in the global heating, ventilation, air conditioning (HVAC), refrigeration, and fire & security industries, Carrier is committed to innovating solutions that improve the environment and enhance human comfort. Founded as an independent entity following its spin-off from United Technologies Corporation in 2020, Carrier operates through three segments: HVAC, Refrigeration, and Fire & Security. The company's key projects often focus on ecological sustainability and energy efficiency, aiming to leverage technology for smarter building and cold chain solutions across a variety of markets. Carrier's strategic endeavors include enhancing its residential HVAC systems and expanding its global reach in the refrigeration sector to support medical and food preservation needs.
Air-Conditioning and Warm Air Heating Equipment and Commercial and Industrial Refrigeration Equipment 55,473.69 105.00 67.54 85.42 65.20 31.00 83.41
1370 STKS / The ONE Group Hospitality, Inc.
The ONE Group Hospitality, Inc., headquartered in the United States, operates primarily within the hospitality industry, specializing in high-energy dining and entertainment. The company is renowned for creating unique, upscale restaurant and lounge experiences, most notably through its STK steakhouse brand, which merges fine dining with a vibrant, club-like atmosphere. These venues are strategically located in major cities across the globe, including in the United States, Europe, the Middle East, and Asia. The ONE Group also successfully extends its hospitality expertise by providing food and beverage hospitality services to hotels, casinos, and other high-end locations. This approach allows The ONE Group to leverage its distinctive brand of hospitality in diverse and lucrative markets, ensuring a broadened customer base and enhanced revenue streams.
Mga Restaurant, Kainan, at Lugar ng Kainan 86.51 6.30 4.24 5.24 2.79 87.33 83.38
1373 CLBT / Cellebrite DI Ltd. Naka-prepack na Software 4,009.29 29.40 18.18 23.46 16.40 43.05 83.36
1374 HGBL / Heritage Global Inc.
Heritage Global acts as an adviser, as well as a principal, acquiring or brokering turnkey manufacturing facilities, surplus industrial machinery and equipment, industrial inventories, accounts receivable portfolios, intellectual property, and entire business enterprises.
Mga Serbisyo sa Negosyo, Hindi Nauuri sa Ibang Lugar 66.36 4.72 3.03 3.75 1.91 96.26 83.36
1375 BBWI / Bath & Body Works, Inc.
Bath & Body Works, Inc., based in the United States, operates primarily in the personal care and home fragrance market. The company is renowned for its extensive range of bath and beauty products, including lotions, soaps, and fragrances, as well as home accessories like scented candles and air fresheners. A key aspect of Bath & Body Works' business strategy involves continuous innovation in its product lines and significant emphasis on seasonal and thematic merchandise offerings, which drive customer engagement and sales. Alongside its robust presence in retail stores, Bath & Body Works also expands comprehensively in the digital and e-commerce sectors, optimizing the synergy between its online and physical retail strategies to enhance overall market reach and consumer satisfaction.
Mga Tindahan, Hindi Nauuri sa Ibang Lugar 6,075.68 46.42 30.30 39.33 29.21 34.63 83.36
1380 NMTRQ / 9 Meters Biopharma, Inc.
9 Meters Biopharma, Inc., headquartered in the United States, operates primarily within the biotechnology industry, focusing on the development of therapies for gastrointestinal ailments. The company is dedicated to pioneering treatments for a range of digestive diseases, including short bowel syndrome (SBS) and celiac disease. One of its key projects involves the drug larazotide, a novel peptide designed to decrease the permeability of the intestine, a critical factor in the management of celiac disease. Additionally, 9 Meters Biopharma is advancing a proprietary long-acting GLP-1 analog, vurolenatide, aimed at treating short bowel syndrome. These initiatives underscore the company's commitment to addressing significant unmet medical needs in the gastrointestinal sector.
Mga Paghahanda sa Parmasyutiko 0.00 83.35
1381 ANIK / Anika Therapeutics, Inc.
Anika Therapeutics, Inc., based in the United States, operates within the healthcare sector, focusing primarily on developing, manufacturing, and commercializing products for joint health and therapeutic pain management. As a leader in hyaluronic acid (HA) therapeutic products for tissue protection, healing, and repair, Anika Therapeutics has established a range of treatment solutions across orthopedics, rheumatology, and ophthalmology. Key projects include its viscosupplementation products designed for individuals suffering from osteoarthritis pain in the knee and other joints. Anika Therapeutics also engages in research and development efforts aimed at expanding its portfolio through both organic growth and strategic acquisitions, strengthening its global market presence in non-operative orthopedic therapies.
Mga Instrumento at Apparatus ng Surgical at Medikal 135.53 25.20 15.15 18.70 9.38 98.94 83.35
1388 CCJ / Cameco Corporation
Cameco Corporation, based in Saskatoon, Saskatchewan, Canada, is a major global player in the uranium mining industry, primarily focused on uranium mining and related services. It operates several high-profile projects that are significant to the global nuclear energy sector. Among these, the McArthur River mine and the Key Lake mill stand out as flagship operations, known for being some of the world’s largest high-grade uranium deposits. Additionally, Cameco holds a strong portfolio in North America, Australia, and Asia. As an integral provider for nuclear power plants worldwide, the company plays a critical role in fueling low-carbon electricity generation, aligning with global energy sustainability goals.
Sari-saring Metal Ore Mining 33,681.57 123.41 78.75 105.32 77.39 36.15 83.31
1389 MNPR / Monopar Therapeutics Inc.
Monopar Therapeutics Inc., based in the United States, is a biopharmaceutical company focusing on developing therapeutic drugs to enhance clinical outcomes for cancer patients. One of their primary projects includes the development of Camsirubicin, a novel analog of the chemotherapy drug doxorubicin, designed to treat soft tissue sarcoma while aiming to reduce cardiotoxicity associated with the original drug. Another significant initiative is MNPR-101, a monoclonal antibody used for imaging and treating severe cancers. The company’s approach emphasizes advancements in the therapeutic profiles of existing treatments, striving for improvements in efficacy and safety to potentially deliver superior patient outcomes in underserved cancer markets.
Mga Paghahanda sa Parmasyutiko 208.89 79.80 40.40 63.41 34.15 86.01 83.31
1393 KLC / KinderCare Learning Companies, Inc. Child Day Care Services 849.30 21.00 9.09 13.26 7.19 84.55 83.28
1397 TE / T1 Energy Inc.
FREYR Battery, Inc., based in Norway, operates within the energy sector, specializing in the production of clean, next-generation battery solutions. The company is primarily focused on delivering high-performance lithium-ion batteries using a production process that leverages renewable energy, aiming to support the transition to greener energy systems globally. A key project includes the development of the Giga Arctic Factory in Mo i Rana, Norway, designed to scale up battery cell production considerably while maintaining a lower carbon footprint than traditional manufacturers. The strategic location and innovative manufacturing approach underline FREYR Battery's commitment to sustainability and position it effectively in the growing electric vehicle and energy storage markets.
Miscellaneous Electrical Machinery, Equipment, and Supplies 257.30 3.15 3.03 3.06 1.65 86.04 83.24
1401 MDAI / Spectral AI, Inc. Mga Instrumento at Apparatus ng Surgical at Medikal 49.67 7.82 3.54 4.96 1.93 156.98 83.23
1408 LOOP / Loop Industries, Inc.
Loop Industries, Inc., based in Canada, operates prominently within the plastics and synthetic rubber manufacturing sector. The company is distinguished by its innovative technology designed to depolymerize no- and low-value waste PET plastics into high-purity recycled PET plastic, suitable for use in food-grade packaging. This proprietary technology enables Loop Industries to support the circular economy by reducing plastic waste and reliance on new petroleum resources. A key project demonstrating the company's ambitions involves a joint venture with Indorama Ventures to establish a manufacturing facility in South Carolina, aimed at producing sustainable PET resin using Loop Industries' recycling process. This strategic initiative exemplifies Loop Industries' commitment to enhancing sustainable practices in plastic production and recycling on a global scale.
Chemicals And Allied Products 71.34 6.09 3.03 4.49 1.49 200.20 83.19
1414 ANGO / AngioDynamics, Inc.
AngioDynamics, Inc., based in the United States, operates primarily in the medical devices sector, focusing on innovative, minimally invasive medical technologies for vascular access, peripheral vascular disease, and oncology. The company has developed a range of products that include catheters, port devices, and oncology surgery and ablation technologies that target the improvement of patient outcomes by enhancing functionality and streamlining procedures. Key projects involve the development and enhancement of their flagship NanoKnife system, a device designed for surgical ablation of soft tissues. AngioDynamics is committed to advancing clinical outcomes and driving technological leadership within the therapeutic areas it serves, aligning its research and development strategies with contemporary clinical needs.
Mga Instrumento at Apparatus ng Surgical at Medikal 420.50 25.20 16.16 18.62 10.26 81.26 83.14
1418 BNZI / Banzai International, Inc. Naka-prepack na Software 8.18 252.00 30.30 137.70 3.32 4,072.73 83.13
1423 GPOR / Gulfport Energy Corporation
Gulfport Energy Corporation, based in the United States, operates primarily within the energy sector, focusing on the exploration, development, and production of natural gas, crude oil, and natural gas liquids. The company has significant involvement in the Utica Shale in Ohio and the SCOOP (South Central Oklahoma Oil Province) play in Oklahoma, which are its key operational projects. These regions are notable for their rich hydrocarbon resources, and Gulfport Energy employs advanced drilling and production technologies to optimize output and efficiency in these areas. As a major player in the U.S. energy market, Gulfport Energy strategically manages a substantial portfolio of assets to sustain its production capabilities and market position.
Crude Petroleum at Natural Gas 3,062.93 285.60 194.93 231.68 174.03 33.12 83.11
1432 ALEC / Alector, Inc.
Alector, Inc., based in the United States, operates primarily in the biotechnology industry, focusing on the development of therapies that harness the human immune system to combat neurodegeneration. The company's innovative approach involves targeting immune dysregulation in the brain, a key factor in neurological disorders such as Alzheimer's disease and frontotemporal dementia. Alector's pipeline includes several key projects like AL001 and AL101, both designed to enhance progranulin levels, thereby potentially modifying the course of neurodegenerative diseases. These projects are in various stages of clinical development, underlining the company's commitment to addressing some of the most challenging conditions affecting the central nervous system.
Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 237.85 10.50 1.01 3.91 2.35 67.09 83.07
1436 CLRB / Cellectar Biosciences, Inc.
Cellectar Biosciences, Inc., based in the United States, primarily operates within the biotechnology industry, focusing on the development of phospholipid drug conjugates (PDCs) designed to provide targeted delivery of oncologic payloads to cancer cells and cancer stem cells. A pivotal project for Cellectar is CLR 131, an investigational radioiodinated therapeutic that targets malignant tumor cells in select hematologic malignancies, including multiple myeloma and other niche cancer types at various stages. This drug has progressed into late-stage clinical trials, emphasizing its role in addressing unmet medical needs in the treatment of complex and rare cancers. Cellectar's strategy underscores a targeted therapeutic approach to improve patient outcomes in oncology through precision medicine.
Mga Paghahanda sa Parmasyutiko 8.82 157.50 18.18 85.68 4.87 1,627.42 83.06
1438 PSTV / Plus Therapeutics, Inc.
Plus Therapeutics, Inc., based in the United States, operates primarily within the biotechnology sector, focusing on the development of innovative treatments for cancer. The company’s portfolio centers on advanced, targeted radiotherapeutics designed to address significant unmet medical needs in the oncology space. Key projects include the development of lead product candidates like Rhenium-186 NanoLiposome (186RNL), which is being investigated under U.S. Food and Drug Administration's orphan drug designation for its potential to treat patients with recurrent glioblastoma, a highly aggressive form of brain cancer. Plus Therapeutics is committed to leveraging nanotechnology and radiotherapy to improve the targeting and efficacy of cancer treatment, positioning itself on the cutting edge of cancer research and therapy advancements.
Mga Instrumento at Apparatus ng Surgical at Medikal 42.40 21.52 3.03 9.01 0.46 1,858.69 83.06
1441 MBRX / Moleculin Biotech, Inc.
Moleculin Biotech, Inc., based in the United States, operates within the biopharmaceutical industry and is primarily focused on the development of oncology drug candidates. Its portfolio includes projects targeting highly resistant tumors and viruses. Notable among its research endeavors is the development of Annamycin, which is being advanced as a potential treatment for acute myeloid leukemia. Additionally, Moleculin is exploring technologies designed to exploit the metabolism of tumors, including a focus on inhibitors that disrupt cancer cell glycolysis and the synthesis of glycosaminoglycans. These efforts embody the company's strategic intent to pioneer treatments for conditions with significant unmet medical needs, demonstrating a promising avenue in cancer treatment research and development.
Mga Paghahanda sa Parmasyutiko 11.85 13.65 4.04 7.14 0.39 1,719.57 83.04
1443 DSP / Viant Technology Inc. Computer Programming, Pagproseso ng Data, At Iba Pang Serbisyong Kaugnay ng Computer 169.10 27.30 15.15 19.89 10.40 91.16 83.03
1444 RANI / Rani Therapeutics Holdings, Inc. Mga Paghahanda sa Parmasyutiko 20.01 12.60 5.05 8.92 0.51 1,650.00 83.01
1446 KNF / Knife River Corporation Pagmimina At Pag-quarry Ng Nonmetallic Minerals, Maliban sa Mga Gatong 4,589.80 137.55 90.90 112.63 81.00 39.00 83.00
1449 VRNT / Verint Systems Inc. Computer Integrated Systems Design 1,227.85 42.00 23.23 30.26 20.39 48.50 83.00
1450 BILL / BILL Holdings, Inc.
BILL Holdings, Inc., based in the United States, operates primarily within the financial technology sector. The company focuses on innovating and providing cloud-based software solutions designed to automate complex back-office financial operations and streamline business payment processes. In pursuit of enhancing efficiency across various industries, BILL Holdings, typically engages in key projects involving the development of scalable platforms for managing invoices, payments, and the integration of artificial intelligence to improve decision-making in financial transactions. Through strategic partnerships and continuous technological advancement, BILL Holdings seeks to expand its reach and refine its offerings, thus positioning itself as a pivotal player in digital finance transformation.
Naka-prepack na Software 4,791.98 93.45 49.49 61.35 46.42 32.11 82.99
1453 FBLG / FibroBiologics, Inc.
FibroBiologics, Inc., based in the United States, operates primarily within the biotechnology sector, focusing on harnessing the therapeutic potential of fibroblasts. Fibroblasts are cells essential for tissue repair and regeneration, making them pivotal in treatment innovations for various diseases. FibroBiologics is actively engaged in developing a diverse pipeline of fibroblast-based therapies, which include projects targeting conditions such as chronic kidney disease, liver cirrhosis, and multiple sclerosis. These initiatives represent the company's commitment to advancing regenerative medicine by exploiting the inherent healing capabilities of fibroblasts, aiming to provide novel treatments that can offer significant improvements over existing therapies in terms of efficacy and safety.
Mga Paghahanda sa Parmasyutiko 24.37 16.80 4.04 10.20 0.59 1,610.26 82.98
1459 PRGS / Progress Software Corporation
Progress Software Corporation, based in the United States, operates within the software industry, focusing primarily on application development, data connectivity, and deployment solutions that enable businesses to accelerate and facilitate digital transformation. Since its inception in 1981, the company has been instrumental in providing technologies ranging from web, mobile, and cloud environments to networked enterprise systems. Key projects and products include the Progress® OpenEdge® development platform, known for enhancing operational efficiency and business agility, and the Telerik® and Kendo UI® tools, which assist developers in creating compelling app experiences across various devices. The corporation also actively engages in acquisitions, such as the recent purchase of Kemp Technologies, to broaden its portfolio and market reach, thereby reinforcing its competitive position in the global tech landscape.
Naka-prepack na Software 1,994.28 87.15 57.57 71.40 46.29 54.31 82.94
1462 ACXP / Acurx Pharmaceuticals, Inc.
Acurx Pharmaceuticals, Inc., based in the United States, primarily operates within the healthcare sector, focusing on the development of antibiotics to combat bacterial infections. This pharmaceutical company is committed to addressing the significant need for new treatments against infections caused by antibiotic-resistant bacteria. A key project of Acurx Pharmaceuticals is the development of a novel class of antibiotics targeting the DNA polymerase IIIC enzyme, essential for bacterial DNA replication. This endeavor is highlighted by its leading candidate, Ibezapolstat, which is in Phase 2 clinical trials and shows promise as a potential treatment for Clostridioides difficile infections (CDI). This initiative reflects the company's strategic focus on innovative antibiotic therapies that can overcome resistance mechanisms.
Mga Paghahanda sa Parmasyutiko 6.82 174.09 20.20 62.93 4.62 1,257.80 82.92
1464 EVER / EverQuote, Inc. Computer Programming, Pagproseso ng Data, At Iba Pang Serbisyong Kaugnay ng Computer 844.24 39.90 33.33 35.70 23.25 53.61 82.92
1466 ARCO / Arcos Dorados Holdings Inc.
Arcos Dorados Holdings Inc. is a major company based in Montevideo, Uruguay, and operates as the largest franchisee of McDonald's restaurants in Latin America and the Caribbean. The company, whose name translates to "Golden Arches," holds the exclusive rights to own, operate, and grant franchises of McDonald's restaurants in 20 countries and territories within the region. Specializing in the fast-food service industry, Arcos Dorados not only emphasizes operational efficiency and sustainable business practices but also invests significantly in digital innovation and infrastructure improvements. Key projects include enhancing digital ordering systems and expanding the McCafé and delivery services as part of its growth and customer engagement strategy. Through such initiatives, Arcos Dorados continues to solidify its market leadership in the Latin American fast-food sector.
Mga Restaurant, Kainan, at Lugar ng Kainan 1,474.64 11.55 8.58 10.32 7.00 47.27 82.91
1473 SKYX / SKYX Platforms Corp. Electric Lighting And Wiring Equipment 127.95 5.25 2.02 3.19 1.16 175.97 82.89
1477 PACS / PACS Group, Inc. 52.50 18.18 33.66 11.64 189.18 82.87
1480 DAVA / Endava plc - Depositary Receipt (Common Stock)
Endava plc is a multinational technology company headquartered in London, United Kingdom. Specializing in the consultation, development, and management of IT solutions, software, and services, Endava has a strong foothold in the financial services, telecommunications, media, technology, and consumer goods industries. Key projects typically include digital transformation, agile development, and automation strategies, aimed at enhancing client operations and customer engagement. Recognized for efficiently integrating strategic consulting with innovative IT solutions, Endava helps businesses streamline processes and foster technological adoption to stay competitive in dynamic market landscapes. As of the last reporting, the company continues to expand its global presence, deploying extensive projects across Europe, North America, and Latin America.
Mga Serbisyo sa Computer Programming 868.53 44.10 14.14 22.65 14.68 54.26 82.86
1485 SPIR / Spire Global, Inc.
Spire Global, Inc. is a U.S.-based data analytics company specializing in the provision of data, analytics, and insights garnered from their proprietary satellite constellation. Established with the mission to harness the vast potential of space to offer unique data perspectives, it operates primarily in the space services and analytics industry. The company's key projects involve global data collection on maritime, aviation, and weather patterns, which they analyze extensively to support various sectors including logistics, maritime shipping, and climate monitoring. Spire Global's services enable enhanced predictive analytics, contributing to more informed decision-making in critical areas such as resource management and emergency response planning. This technical and data-centric focus renders Spire Global a pivotal player in the evolving landscape of global data-driven enterprises.
Mga Serbisyo sa Komunikasyon, Hindi Nauuri sa Ibang Lugar 279.94 17.85 15.15 16.58 9.04 83.15 82.82
1486 CBUS / Cibus, Inc. Mga Kemikal na Pang-agrikultura 69.80 26.25 1.62 14.69 1.34 1,004.36 82.81
1488 AEYE / AudioEye, Inc. Naka-prepack na Software 155.04 26.25 19.19 22.64 12.85 76.29 82.81
1489 SKYH / Sky Harbour Group Corporation Serbisyong Elektrisidad 356.62 26.25 12.12 17.41 10.54 65.21 82.80
1490 CLSD / Clearside Biomedical, Inc.
Clearside Biomedical, Inc., based in the United States, operates within the biopharmaceutical industry, primarily focusing on the development of innovative therapies for eye diseases. The company's groundbreaking approach involves using their proprietary SCS Microinjector to deliver medication directly to the suprachoroidal space, targeting diseases such as uveitis, retinal vein occlusion, and diabetic macular edema. Key projects include XIPERE, a treatment for macular edema associated with uveitis, which exemplifies their commitment to addressing unmet medical needs in ophthalmology. This strategic focus on targeted, site-specific administration of therapeutics represents a significant part of their operations and overall mission to enhance patient outcomes in the realm of eye health.
Mga Paghahanda sa Parmasyutiko 28.68 6.30 2.02 4.28 0.37 1,072.41 82.79
1492 PMTS / CPI Card Group Inc.
CPI Card Group Inc., based in the United States, operates primarily in the financial and security card production industry. The company is a leading provider in the design, production, data security, and related services for financial payment cards, including EMV chip and magnetic stripe debit, credit, and prepaid cards. CPI Card Group also engages in creating innovative card solutions like dual-interface and metal cards, catering to evolving consumer and financial industry demands. Their key projects often focus on enhancing card security features, customization, and the integration of mobile technology, aiming to streamline card issuance systems and improve client engagement through technological advancements. The firm's commitment to sustainability is evident in its development of eco-focused card materials, which align with the broader industry's push towards environmental responsibility.
Commercial Printing 175.58 42.00 30.30 34.68 15.58 123.89 82.78
1500 QNST / QuinStreet, Inc.
QuinStreet, Inc., based in the United States, primarily operates within the digital marketing industry, specializing in performance marketing products and technologies. The company's innovative approach focuses on connecting online advertising clients with their potential customers through various media channels and platforms, essentially driving customer acquisition in high-intent verticals such as financial services, education, home services, and business-to-business technology. Founded in 1999, QuinStreet leverages its proprietary technologies for precision targeting and optimization, helping clients increase their visibility and engagement with relevant consumer segments. The company emphasizes robust data analytics and digital strategies to deliver measurable outcomes, shaping it as a leader in its field.
Mga Serbisyo sa Negosyo, Hindi Nauuri sa Ibang Lugar 895.94 30.45 18.18 23.15 15.68 47.48 82.77
1501 LGVN / Longeveron Inc. Mga Paghahanda sa Parmasyutiko 12.54 10.97 3.03 7.00 0.83 752.59 82.76
1505 WY / Weyerhaeuser Company
Weyerhaeuser Company, based in the United States, is a leading organization in the forest products industry. Founded in 1900 and headquartered in Seattle, Washington, it specializes in the management of timberlands and the manufacture of wood and specialty cellulose fibers products. Weyerhaeuser owns or controls approximately 11 million acres of timberlands in the U.S. and manages additional timberlands under long-term licenses in Canada. The company leverages its extensive resources for sustainable timber harvesting and the production of wood products used in construction and other applications. Key projects often focus on innovative forest management practices, enhancing yield, and improving the environmental footprint of forestry operations, aligning with global sustainability trends in resource management.
Mga Trust sa Pamumuhunan sa Real Estate 18,665.49 39.90 29.29 34.37 25.87 32.87 82.75
1506 AVNW / Aviat Networks, Inc.
Aviat Networks, Inc., based in the United States, operates primarily within the telecommunications equipment industry. This company specializes in designing and manufacturing wireless networking solutions, notably for network operators, service providers, and private network users spanning various sectors, including utility, public safety, and government bodies. Aviat Networks emphasizes advancements in microwave networking and related technologies, underpinned by robust research and development efforts aimed at driving the next generation of communication networks. Key projects have included deploying microwave backhaul and transport systems, which are vital for enhancing the connectivity, capacity, and reliability of broadband networks in underserved or challenging geographical areas.
Kagamitan sa Pag-broadcast sa Radyo at Telebisyon at Komunikasyon 291.41 44.10 30.30 35.12 22.96 53.28 82.74
1507 BJ / BJ's Wholesale Club Holdings, Inc.
BJ's Wholesale Club Holdings, Inc., based in the United States, is a prominent player in the retail sector, specifically within the warehouse club industry. The company operates through a membership-only warehouse club model, providing a wide array of merchandise including groceries, electronics, home goods, and health products. BJ's strategically positions itself by offering significant discounts on bulk purchases to its individual and business members. A key component of their business strategy includes expanding their digital presence and enhancing omnichannel capabilities, catering to a growing demand for convenience in shopping experiences. Additionally, BJ's has been actively involved in developing private label products that not only strengthen customer loyalty but also improve profit margins by minimizing reliance on third-party vendors.
Iba't ibang Tindahan 12,874.13 147.00 73.15 126.06 97.68 29.04 82.74
1508 LSTA / Lisata Therapeutics, Inc.
Lisata Therapeutics, Inc., based in the United States, operates primarily in the biotechnology industry, focusing on the development of innovative cancer treatments. The company is notable for its advanced therapeutic platforms which harness proprietary technologies aimed at enhancing the effectiveness and safety of cancer therapies. A key project for Lisata Therapeutics is the development of novel oncolytic viral therapies designed to selectively target and destroy cancer cells while sparing healthy tissues. This project reflects the company's commitment to advancing oncological outcomes through targeted and minimally invasive approaches. Through its pioneering research and development efforts, Lisata Therapeutics is positioned at the forefront of biotechnological innovations in oncology.
Mga Paghahanda sa Parmasyutiko 20.01 33.60 15.15 21.08 2.32 808.62 82.74
1511 TLPH / Talphera, Inc.
Talphera, Inc. is an American technology firm specializing in artificial intelligence and machine learning. Based in Silicon Valley, it primarily develops advanced AI algorithms and data analytics solutions aimed at enhancing predictive capabilities in various tech-driven sectors. Key projects include the development of a proprietary AI platform that assists in real-time decision-making processes for financial services and an innovative machine-learning application that enhances automation in manufacturing environments. These initiatives underscore Talphera's commitment to pushing the boundaries of AI technology to drive efficiency and innovation. The company has successfully partnered with major industry players, positioning itself as a crucial contributor to technological advancements in AI applications.
Mga Paghahanda sa Parmasyutiko 11.03 6.30 3.03 4.25 0.54 691.00 82.73
1518 KAPA / Kairos Pharma, Ltd. 24.31 12.60 4.04 8.50 1.35 520.44 82.70
1520 CELC / Celcuity Inc. Mga Medikal na Laboratoryo 1,993.57 82.95 60.60 70.82 51.23 38.29 82.69
1521 LOVE / The Lovesac Company Furniture Stores 278.33 36.75 24.24 29.17 19.13 52.57 82.69
1526 CORZ / Core Scientific, Inc. Mga Serbisyo sa Pananalapi 4,353.18 25.30 15.15 19.22 14.35 33.82 82.67
1532 KMDA / Kamada Ltd. Mga Paghahanda sa Parmasyutiko 391.72 21.00 13.13 16.32 6.92 135.84 82.63
1533 REGN / Regeneron Pharmaceuticals, Inc.
Regeneron Pharmaceuticals, Inc. is an American biotechnology company primarily engaged in the research, development, and commercialization of pharmaceutical products for the treatment of serious medical conditions. Headquartered in Tarrytown, New York, Regeneron is a leader in the field of biopharmaceuticals, with a robust portfolio of products targeting oncology, cardiovascular diseases, and infectious diseases, among others. Significant projects include the development of Eylea, a treatment for macular degeneration, and Dupixent, a drug designed for asthma and dermatology treatments. Regeneron is also noted for its rapid development of REGEN-COV, a monoclonal antibody cocktail for COVID-19. The company's commitment to high scientific standards and rapid innovation continues to drive its success in biotechnology.
Mga Paghahanda sa Parmasyutiko 60,460.83 1,063.65 548.43 745.42 580.70 28.29 82.63
1534 MDXG / MiMedx Group, Inc. Mga Instrumento at Apparatus ng Surgical at Medikal 1,048.79 13.65 12.12 12.44 7.10 75.51 82.63
1536 SMPL / The Simply Good Foods Company
The Simply Good Foods Company, based in the United States, operates within the consumer goods sector, specifically focusing on the health and wellness industry. The company is renowned for developing and marketing nutritional foods and snack products, aiming to cater to health-conscious consumers. Its portfolio includes a variety of protein bars, ready-to-drink shakes, and snacks under popular brands such as Atkins and Quest. The Simply Good Foods Company emphasizes innovation in its product lines and maintains a strong market presence through strategic marketing and distribution channels. A key project for the company involves expanding its product offerings while continuing to enhance nutritional value, thereby supporting healthier lifestyle choices for its customers. This strategy is pivotal in driving the company's growth and aligns with current consumer trends towards healthier eating habits.
Pagkain At Mga Kamag-anak na Produkto 2,878.04 47.25 34.34 39.52 28.63 38.05 82.62
1537 ESTA / Establishment Labs Holdings Inc. Mga Orthopedic, Prosthetic, at Surgical Appliances at Supplies 1,195.57 73.50 40.40 57.88 41.27 40.26 82.62
1541 PONY / Pony AI Inc. - Depositary Receipt (Common Stock) 5,278.70 25.72 15.40 20.53 14.37 42.65 82.59
1543 RBBN / Ribbon Communications Inc.
Ribbon Communications Inc., based in the United States, is a prominent entity in the telecommunications sector specializing in IP-based real-time communication solutions. The company is focused on providing advanced software and network solutions to secure and transform the communications infrastructure for service providers and large enterprises. Ribbon’s key projects largely encompass the development of Voice over Internet Protocol (VoIP), session border controllers (SBC), and unified communications (UC) systems. Additionally, the company places a strategic emphasis on cloud communications and security technologies, assisting clients in transitioning smoothly to next-generation networks while optimizing their operational efficiencies and enhancing service offerings. Through its innovative product portfolio and strategic initiatives, Ribbon aims to address the rising demand for high-quality, secure, and reliable communication solutions.
Computer Integrated Systems Design 722.02 6.82 6.06 6.20 4.08 51.90 82.57
1547 AMIX / Autonomix Medical, Inc. Mga Instrumento at Apparatus ng Surgical at Medikal 4.51 8.61 5.05 6.73 1.12 504.53 82.55
1550 NOW / ServiceNow, Inc.
ServiceNow, Inc., based in the United States, operates within the software industry, specializing primarily in enterprise cloud computing solutions. The company focuses on creating digital workflows that facilitate enterprise operations across departments such as human resources, customer service, and security within an organization. Key projects include the development of its flagship platform, Now Platform, which supports a suite of applications designed to optimize business processes and enhance productivity. This platform integrates artificial intelligence and machine learning to automate tasks, enable predictive analytics, and provide a comprehensive, scalable approach to enterprise management. Service:Now’s strategic emphasis on continuous innovation and customer satisfaction has solidibelt established it as a leader in the cloud computing and IT service management sectors.
Naka-prepack na Software 189,914.22 1,365.00 741.34 1,168.78 917.46 27.32 82.54
1553 NX / Quanex Building Products Corporation
Quanex Building Products Corporation, based in the United States, operates primarily within the building and construction industry. The company specializes in components that enhance the energy efficiency of windows, doors, and solar panels. A significant area of focus for Quanex includes the manufacturing of fenestration products such as window and door profiles, which constitute a substantial portion of its business operations. The corporation leverages advanced material science to innovate sustainable and energy-efficient solutions tailored to the specific needs of residential and commercial construction markets. Key projects often involve collaborations with leading construction firms to integrate Quanex’s high-performance products in a diverse range of architectural projects, thereby supporting the industry's shift towards greener building practices.
Rolling, Drawing, At Extruding Ng Nonferrous 988.69 39.90 28.28 34.42 21.27 61.92 82.53
1554 TRUG / TruGolf Holdings, Inc. Barang Olahraga dan Atletik, Tidak Diklasifikasikan di Tempat Lain 4.19 52.50 14.14 32.64 4.19 682.73 82.52
1557 RIOT / Riot Platforms, Inc.
Riot Platforms, Inc., based in the United States, operates in the cryptocurrency sector with a focus on Bitcoin mining. It is one of the leading Bitcoin miners in North America, engaging in the provision, infrastructure, and management essential for blockchain ecosystem support. The company has significantly invested in expanding and optimizing its mining operations, which include a large-scale, energy-efficient mining facility in Texas. Additionally, Riot Platforms emphasizes innovations in digital currency technology and continually adapts its strategies to align with the evolving regulatory and economic landscape surrounding cryptocurrency. Through strategic acquisitions, Riot not only expands its capacity and operational capabilities but also enhances its technological assets, aiming to foster both scalability and sustainability in its operations.
Mga Serbisyo sa Pananalapi 5,001.73 25.20 11.11 18.04 13.76 31.02 82.51
1559 BIIB / Biogen Inc.
Biogen Inc., based in the United States, is a prominent biotechnology firm that operates primarily in the healthcare sector. The company is renowned for its pioneering work in neuroscience, focusing on developing therapies for neurodegenerative, hematologic, and autoimmune diseases. Key projects include research and development in areas like Alzheimer’s disease, multiple sclerosis, and spinal muscular atrophy. Biogen’s commitment to innovation is evident from its robust pipeline of potential treatments undergoing various stages of clinical trials. Additionally, Biogen is involved in collaborations that aim to advance the understanding of complex neurodegenerative diseases and improve the management of these conditions, further underscoring its role as a leader in biotechnological advancements within the neurological field.
Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 19,385.38 273.00 119.18 171.86 132.22 30.05 82.51
1597 LTH / Life Time Group Holdings, Inc. Membership Sports and Recreation Clubs 6,139.66 47.25 32.32 39.81 27.92 42.52 82.36
1598 PROK / ProKidney Corp. Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 314.87 10.50 1.01 5.95 2.36 152.12 82.36
1600 QBTS / D-Wave Quantum Inc.
D-Wave Quantum Inc. is a Canadian-based company established in 1999, pioneering in the quantum computing industry. The company primarily develops and distributes quantum computers. D-Wave's notable project, the D-Wave System, exemplifies the practical application of quantum annealing technology to solve complex computational problems faster than traditional binary computers. The firm has collaborated extensively with entities in sectors such angiery, life sciences, and finance, aiming to transform problem-solving paradigms through quantum computing advantages. D-Wave Quantum Inc. stands out for its focus on producing scalable quantum computing solutions and has attracted significant attention for setting benchmarks in performance and system innovation within the field of quantum technology.
Mga Serbisyo sa Pagproseso ng Computer at Paghahanda at Pagproseso ng Data 5,308.26 31.50 20.20 22.64 15.62 44.88 82.34
1601 LXRX / Lexicon Pharmaceuticals, Inc.
Lexicon Pharmaceuticals, Inc., headquartered in the United States, operates within the biotechnology sector, primarily focused on the development and commercialization of breakthrough treatments for human disease. The company has concentrated its efforts on diabetes and cardiovascular diseases, among other serious health conditions. A key project includes their development of sotagliflozin, a drug designed to treat diabetes by improving glycemic control without necessitating insulin. The company leverages its unique bioinformatics and genetics understanding to pioneer these medications, aiming to meet significant unmet medical needs in the chronic disease sphere. Lexicon Pharmaceuticals has built a robust pipeline of drug candidates that are in various stages of clinical development, reinforcing its commitment to innovation in therapeutic healthcare solutions.
Mga Paghahanda sa Parmasyutiko 401.56 6.30 0.86 2.80 1.10 153.85 82.33
1604 QTWO / Q2 Holdings, Inc. Naka-prepack na Software 4,916.06 120.75 74.74 104.56 78.73 32.84 82.33
1605 STZ / Constellation Brands, Inc.
Constellation Brands, Inc., headquartered in Victor, New York, USA, operates as a leading international beverage alcohol company. Positioned primarily in the alcoholic beverages industry, it specializes in the production and marketing of beer, wine, and spirits. Notably, the company boasts a robust portfolio featuring premium brands such as Corona and Modelo—key drivers in its high-performing beer segment that specifically cater to the U.S. market. In addition to its emphasis on premium alcohol, Constellation Brands has strategically expanded its footprint in the cannabis industry through a significant investment in Canopy Growth Corporation, reflecting its interest in emerging markets and innovative product lines. This alliance underscores the company’s forward-looking approach, focusing on next-generation products and market expansion opportunities.
Mga inumin 28,793.09 315.00 171.70 213.82 161.94 32.09 82.32
1606 TENB / Tenable Holdings, Inc.
Tenable Holdings, Inc., based in the United States, operates primarily in the cybersecurity industry. The company specializes in vulnerability management and offers products that enable organizations to identify, manage, and mitigate cybersecurity risks. Its flagship solution, Nessus, is widely recognized as one of the most comprehensive vulnerability scanning technologies globally. Tenable continually advances its technological capabilities through research and development, emphasizing scalable solutions tailored for varying organizational sizes, from small businesses to large enterprises. Key initiatives include expanding its cloud security offerings and enhancing machine learning capabilities to predict necessary security measures. Tenable actively contributes to the broader cybersecurity community by providing insights and fostering collaborations that enhance collective security resilience.
Naka-prepack na Software 3,738.50 47.25 32.32 40.54 30.92 31.21 82.31
1611 FVRR / Fiverr International Ltd.
Fiverr International Ltd., based in Israel, operates an online platform that connects freelancers with potential clients, effectively facilitating the exchange of digital services across various categories such as graphic design, digital marketing, and software development. As a leader in the gig economy, Fiverr capitalizes on a broad trend towards independent freelance work by providing a structured marketplace where freelancers can offer specific "Gigs," allowing them to build personal brands with the supportive tools and global outreach the platform offers. Key projects and initiatives often revolve around platform enhancements, expansion into new markets, and the introduction of new service categories to match evolving market demands and technological advancements. This strategic focus supports Fiverr's mission to reshape the future of how the world works together, fostering a creative and professional environment for freelancers and clients alike.
Mga Serbisyo sa Negosyo, Hindi Nauuri sa Ibang Lugar 868.16 46.20 25.25 33.53 23.55 42.45 82.28
1614 PDSB / PDS Biotechnology Corporation
PDS Biotechnology Corporation, based in the United States, operates primarily within the biotechnology sector, focusing on the development of novel immunotherapies for cancer and infectious diseases. The company employs its proprietary Versamune® platform, which is designed to activate the immune system's T-cells to specifically target and attack diseased cells. Key projects include a variety of clinical-stage cancer immunotherapies, such as PDS0101, which targets HPV-associated cancers through a combination treatment approach. PDS Biotechnology's approach emphasizes a more targeted and potentially less toxic treatment regime, aiming to significantly improve patient outcomes in areas with critical unmet medical needs. The company's innovative research and development strategies hold potential for significant contributions to medical science and patient care.
Mga Paghahanda sa Parmasyutiko 57.83 13.65 4.54 7.65 1.24 521.95 82.27
1616 BTAI / BioXcel Therapeutics, Inc.
BioXcel Therapeutics, Inc., based in the United States, is an emerging biopharmaceutical company dedicated to the development of innovative drugs leveraging artificial intelligence to address diseases with significant unmet medical needs. Operating primarily within the pharmaceutical industry, the company focuses on pioneering developments in neuroscience and immuno-oncology. Key projects include BXCL501, a proprietary, orally dissolving film formulation designed for the treatment of agitation associated with neurological disorders such as schizophrenia and bipolar disorder. Additionally, BioXcel is developing BXCL701, an investigational orally bioavailable systemic innate immunity activator for aggressive forms of prostate cancer and advanced solid tumors. These projects highlight the company’s commitment to integrating cutting-edge technology with targeted therapies to address complex medical challenges.
Mga Paghahanda sa Parmasyutiko 26.81 69.30 1.01 17.17 4.05 326.05 82.27
1617 AEVA / Aeva Technologies, Inc. Mga Bahagi at Accessory ng Sasakyan ng Motor 816.66 34.65 19.19 26.72 14.80 80.51 82.27
1625 HAIN / The Hain Celestial Group, Inc.
The Hain Celestial Group, Inc., based in the United States, operates primarily in the organic and natural products industry. The company is a leading producer of organic and natural foods, beverages, and personal care products, with a focus on health-conscious consumers. The Hain Celestial Group manages a diverse portfolio of brands across several product categories such as dairy alternatives, snacks, teas, and skincare. Its key projects typically involve product innovation, sustainability initiatives, and expanding market reach through strategic acquisitions that complement its core business. These efforts are driven by a commitment to providing consumers with healthier and more environmentally friendly product options, aligning with the growing global demand for organic and natural products.
Pagkain At Mga Kamag-anak na Produkto 162.00 5.25 1.52 3.19 1.80 77.50 82.22
1632 TRU / TransUnion Mga Ahensya sa Pag-uulat ng Consumer Credit, Mercantile 17,220.32 141.75 84.84 115.32 88.40 30.45 82.19
1636 ITRG / Integra Resources Corp.
Integra Resources Corp., based in Canada, is a prominent player in the minerals exploration sector, focusing predominantly on the acquisition, exploration, and development of precious and base metals properties. The company's primary project is the DeLamar Project located in southwestern Idaho, USA, which comprises the historically significant DeLamar and Florida Mountain gold and silver mines. This project is distinguished by its substantial low-sulphidation epithermal gold-silver deposit. Integra Resources is leveraging advanced exploration techniques and comprehensive drilling programs aimed at delineating and expanding its resource base, with the ultimate goal of reviving and modernizing these historically productive mines, thereby enhancing their economic viability and sustainability within the industry.
Pagmimina ng Ginto At Pilak 385.33 5.35 2.76 3.52 2.29 54.20 82.17
1647 IAC / IAC Inc.
IAC Inc. is a leading media and Internet company based in the United States, renowned for building and acquiring innovative businesses within the digital landscape. It operates across a diverse array of sectors, including online dating, consumer services, and digital content markets. IAC's key projects and businesses have historically included prominent names like Vimeo and Dotdash, reflecting its expertise in nurturing high-growth potential entities into independent publicly traded companies. This strategic focus on incubating and spinning off successful verticals has uniquely positioned IAC to continuously adapt and thrive in the dynamic digital ecosystem. The company's entrepreneurial approach to both acquisitions and organic growth remains a cornerstone of its sustained success and strategic evolution.
Computer Programming, Pagproseso ng Data, At Iba Pang Serbisyong Kaugnay ng Computer 63.00 39.39 49.98 36.62 36.59 82.13
1652 BLZE / Backblaze, Inc. Naka-prepack na Software 471.18 16.70 8.08 11.53 8.35 38.12 82.09
1653 RBRK / Rubrik, Inc. 17,127.44 131.25 97.97 114.19 89.40 27.76 82.07
1655 DVAX / Dynavax Technologies Corporation
Dynavax Technologies Corporation, based in the United States, primarily operates within the biopharmaceutical industry. The company is focused on leveraging the power of the body's innate and adaptive immune responses through its proprietary toll-like receptor (TLR) stimulation technology. One of its notable products is HEPLISAV-B, a hepatitis B vaccine that offers enhanced immunogenicity and convenience with a two-dose regimen, compared to the typical three-dose schedule of other available vaccines. Dynavax also actively collaborates on various projects aimed at developing vaccines for infectious diseases, including a collaboration on a COVID-19 vaccine. These projects illustrate Dynavax's strategic emphasis on innovation and partnerships to expand its vaccine technology applications.
Mga Paghahanda sa Parmasyutiko 1,186.37 33.60 11.11 24.48 10.12 141.90 82.07
1656 NCMI / National CineMedia, Inc. Advertising 410.60 7.88 5.56 6.94 4.39 57.82 82.06
1657 GKOS / Glaukos Corporation
Glaukos Corporation, headquartered in the United States, operates primarily within the medical device industry, focusing on the development and commercialization of therapies for the treatment of glaucoma. Established with the aim to improve the lives of patients worldwide, Glaukos pioneered Micro-Invasive Glaucoma Surgery (MIGS) with the introduction of its flagship product, the iStent, a device designed to reduce intraocular pressure in glaucoma patients. The company's innovative portfolio has expanded to include a range of products that enhance the ocular health of patients with glaucoma and corneal disorders. By constantly innovating and exploring new solutions, Glaukos Corporation actively fortifies its position in specialized ophthalmic markets, underscoring its commitment to progressive ophthalmic therapies.
Mga Instrumento at Apparatus ng Surgical at Medikal 5,485.60 173.25 72.72 124.78 95.82 30.22 82.06
1658 TRC / Tejon Ranch Co.
Tejon Ranch Co., based in the United States, operates primarily in the real estate and agriculture sectors. As one of the largest landowners in California, the company manages over 270,000 acres of land, engaging in commercial and industrial real estate development, resort/residential development, and farming activities. Key projects include the Tejon Ranch Commerce Center, a commercial hub strategically positioned along Interstate 5, which has attracted major tenants such as IKEA and Caterpillar. Additionally, the company is developing master-planned communities, notably the Centennial Project, which aims to construct around 19,000 homes and commercial facilities, addressing housing shortages in the region. Through these endeavors, Tejon Ranch Co. leverages its substantial land assets to generate sustainable growth and shareholder value.
Real Estate 467.99 27.56 26.51 26.78 17.41 53.88 82.06
1661 SMSI / Smith Micro Software, Inc.
Smith Micro Software, Inc., based in the United States, operates within the software industry, specializing in the development and marketing of telecommunications and graphics software. The company has made significant strides in the wireless communications sector, and offers innovative solutions designed to enhance device and network security, boost connectivity, and improve user experience across various digital platforms. Among its prominent projects are the SafePath® family solutions, which provide family location and parental controls, CommSuite® that manages voice messages and Visual Voicemail, and ViewSpot®, a retail display management platform. Smith Micro Software also has a storied history in graphic design through products like Moho®, a tool for creating 2D animations. This portfolio underscores the company’s commitment to utilizing technology to create integrated user environments across multiple digital touchpoints.
Naka-prepack na Software 14.46 5.25 1.52 3.57 0.74 378.55 82.04
1662 NMRA / Neumora Therapeutics, Inc. Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 280.98 18.90 2.02 7.14 1.73 311.53 82.04
1663 FANG / Diamondback Energy, Inc.
Diamondback Energy, Inc., based in the United States, primarily operates in the oil and natural gas sector. The company is engaged in the acquisition, development, exploration, and exploitation of unconventional, onshore oil and natural gas reserves in the Permian Basin in West Texas. Key projects focus on horizontal drilling and hydraulic fracturing to enhance resource extraction from shale formations, with significant operations in the Midland and Delaware sub-basins. As a leading player in the energy industry, Diamondback Energy is committed to boosting production efficiency and optimizing well performance through advanced extraction technologies and innovative operational practices, thereby maintaining its competitive edge and contributing substantially to the U.S. energy output.
Crude Petroleum at Natural Gas 43,312.26 233.10 144.43 188.49 148.76 26.67 82.04
1667 PCG / PG&E Corporation
PG&E Corporation, headquartered in San Francisco, California, USA, operates as a primary player in the energy sector, specifically focusing on electricity and natural gas. Predominantly serving Northern and Central California, it delivers some of the nation's cleanest energy. Under its subsidiary Pacific Gas and Electric Company, PG&E Corporation manages a comprehensive portfolio of energy generation and distribution services to approximately 16 million people. Key projects have notably included infrastructure upgrades to enhance system safety and resilience, and substantial investments in renewable energy sources to align with California's environmental goals. Recent years have seen the corporation navigating financial and regulatory challenges, particularly concerning its role in regional wildfires, impacting its strategic and operational priorities.
Pinagsamang Electric at Iba Pang Serbisyo 33,582.96 24.15 17.17 20.66 15.28 35.09 82.03
1671 HNST / The Honest Company, Inc. Mga Katalogo at Bahay-Kalakal na Nagbebenta sa Pamamagitan ng Pagpapadala 441.38 8.40 4.29 6.93 3.96 75.16 82.01
1673 FBRX / Forte Biosciences, Inc.
Forte Biosciences, Inc., based in the United States, operates within the biotechnology sector, focusing specifically on the development of dermatology therapies. The company pioneers innovative treatments for inflammatory skin diseases, aiming to address unmet medical needs. Key projects include their leading program, FB-401, which is a live biotherapeutic for the treatment of inflammatory skin conditions such as atopic dermatitis. The development of FB-401 reflects Forte Biosciences' commitment to leveraging cutting-edge scientific research to improve patient outcomes in dermatological conditions. The company's strategic initiatives prioritize robust clinical trials and the pursuit of novel therapeutic pathways, aiming to provide groundbreaking solutions in the realm of dermatological healthcare.
Mga Paghahanda sa Parmasyutiko 194.50 64.05 19.19 45.56 11.00 314.18 82.01
1678 ACTU / Actuate Therapeutics, Inc. Naka-prepack na Software 172.77 36.75 20.20 29.58 8.44 250.47 81.99
1681 OPAL / OPAL Fuels Inc. Pinagsamang Gas at Iba Pang Serbisyo 67.85 7.35 2.02 4.05 2.35 73.00 81.96
1683 OKE / ONEOK, Inc.
ONEOK, Inc. is an American multinational corporation headquartered in Tulsa, Oklahoma, primarily engaged in the energy sector. As a significant player in the midstream service industry, ONEOK specializes in the gathering, processing, storage, and transportation of natural gas and natural gas liquids (NGLs). The company operates major infrastructure projects across the United States, including extensive pipelines and storage facilities that play a crucial role in energy supply and logistics. Key projects include the expansion of the West Texas LPG Pipeline and the Elk Creek Pipeline, which significantly enhance its capacity to transport NGLs from the Rocky Mountain and Mid-Continent regions to key market centers. These strategic initiatives align with the growing demand for energy infrastructure and underscore ONEOK's pivotal role in supporting both upstream producers and downstream consumers within the energy sector.
Natural Gas Transmission and Distribution 48,100.25 132.30 83.83 100.33 76.38 31.35 81.96
1685 TKNO / Alpha Teknova, Inc. Mga In Vitro at In Vivo Diagnostic Substances 230.63 12.60 8.08 10.20 4.32 136.38 81.95
1688 IBIO / iBio, Inc.
iBio, Inc., headquartered in the United States, operates within the biotechnology industry, focusing primarily on developing plant-based biopharmaceuticals. The company leverages its proprietary technologies, including the FastPharming System, designed to produce proteins rapidly and at a lower cost than traditional methods. This technology applies to both therapeutic and vaccine development, addressing a range of diseases. A key project includes their work on a COVID-19 vaccine candidate, which exemplifies their rapid response capabilities in vaccine development. iBio, Inc. also engages in collaboration projects aimed at improving drug formulation and delivery, further solidifying its position as a versatile player in the biotechnological and pharmaceutical sectors.
Mga Paghahanda sa Parmasyutiko 8.24 6.30 3.64 4.96 0.82 506.78 81.92
1689 SNCR / Synchronoss Technologies, Inc.
Synchronoss Technologies, Inc., based in the United States, operates primarily within the cloud, messaging, and digital products services industries. Established to innovate within telecommunications and technology markets, the company offers personalized cloud solutions, secure messaging services, and digital transformation products. Synchronoss facilitates enhanced connectivity and workflow between clients and enterprises by leveraging their platforms to synchronize and enrich user experiences across numerous devices and networks. Key projects involve collaborations with major telecommunications companies to develop and manage digital and cloud platforms designed to optimize customer engagement and revenue opportunities. Through these initiatives, Synchronoss aims to empower seamless integration of services and introduce efficiency across the tech-driven landscapes frequented by businesses and consumers alike.
Mga Serbisyo sa Computer Programming 64.90 42.00 13.13 27.03 6.02 349.75 81.92
1693 THRY / Thryv Holdings, Inc. Advertising 565.33 27.30 16.16 22.18 12.86 72.38 81.91
1697 CWEN.A / Clearway Energy, Inc.
Clearway Energy, Inc., based in the United States, operates in the renewable energy sector, focusing on the ownership and operation of contracted renewable power generation facilities. With a commitment to clean energy, the company's portfolio includes wind, solar, and natural gas projects. Notably, Clearway Energy has made significant strides in advancing solar energy with large-scale installations across the U.S. The company also plays a crucial role in developing and managing wind energy projects, helping to increase the country's renewable energy capacity. Integral to its strategy is the emphasis on long-term, power purchase agreements (PPAs), which provide stable revenue streams and align with global shifts towards sustainable energy practices.
Serbisyong Elektrisidad 3,457.86 42.00 33.47 37.28 28.19 32.29 81.89
1701 CRNT / Ceragon Networks Ltd.
Ceragon Networks Ltd. is an Israeli-based company specializing in the design and manufacture of innovative wireless backhaul solutions, a crucial component for mobile and fixed telecommunications operators. Ceragon's primary industry revolves around the provision of equipment and technologies that facilitate effective and efficient data transmission and broadband services over wireless networks. The company’s key projects typically involve deploying high-capacity, point-to-point wireless communications systems that support the growing demand for data-heavy applications. Notable for serving both established and emerging markets, Ceragon helps expand mobile and internet coverage by implementing scalable and cost-effective network infrastructures. These projects are critical to enabling 5G deployment, enhancing Internet of Things (IoT) connectivity, and bridging the digital divide in underserved areas.
Kagamitan sa Pag-broadcast sa Radyo at Telebisyon at Komunikasyon 182.52 9.45 3.03 4.84 2.03 137.50 81.87
1702 QDEL / QuidelOrtho Corporation
QuidelOrtho Corporation is a leading entity in the healthcare industry, primarily focusing on diagnostics healthcare solutions. Based in the United States, the corporation delivers a comprehensive range of products and technologies that are central to diagnostic testing for infectious diseases, cardiometabolic issues, and toxicology. Among its key projects, QuidelOrtho excels in rapid point-of-care testing kits and robust laboratory equipment, which are pivotal in advancing global health standards. The company, through its innovative pursuits, has positioned itself at the forefront of addressing crucial health challenges, implementing streamlined diagnostics that significantly enhance patient care and clinical outcomes. QuidelOrtho's enduring commitment to innovation and accessibility in diagnostic healthcare continues to drive its strategic operations and market expansion.
Mga In Vitro at In Vivo Diagnostic Substances 1,942.31 63.00 26.26 44.88 28.69 56.43 81.87
1708 GMED / Globus Medical, Inc.
Globus Medical, Inc., headquartered in the United States, operates primarily within the medical devices industry, specializing in the design, development, and commercialization of musculoskeletal solutions. The company is recognised for its innovative approaches in products that promote healing in patients with spine disorders, and it holds a leading market position in orthopedic implants. Noteworthy projects include the development of the ExcelsiusGPS, a robotic navigation system for spine and orthopedic surgery, which represents a significant advancement in integrating robotics, imaging, and navigation technologies. Glob at forefront in its commitment to advancing healthcare through technological breakthroughs, Globus Medical continues to expand its product range and enhance treatment solutions across the global medical community.
Mga Instrumento at Apparatus ng Surgical at Medikal 8,274.53 111.30 65.65 84.20 61.27 37.31 81.84
1711 XOMA / XOMA Royalty Corporation Mga Paghahanda sa Parmasyutiko 391.67 109.20 35.35 65.96 32.47 103.77 81.84
1712 ZSPC / zSpace, Inc. 48.53 5.25 3.03 4.42 2.11 109.48 81.84
1714 SEPN / Septerna, Inc. 538.83 27.30 18.18 23.46 12.10 94.04 81.83
1721 LUNR / Intuitive Machines, Inc.
Intuitive Machines Inc. adalah perusahaan kedirgantaraan swasta Amerika. Perusahaan ini berfokus pada pengembangan sistem otonom dan pesawat ruang angkasa untuk misi bulan dan ruang angkasa jauh.
Search, Detection, Navigation, Guidance, Aeronautical, at Nautical System and Instruments 1,031.87 19.42 10.60 15.07 8.77 71.87 81.82
1724 AMTX / Aemetis, Inc.
Aemetis, Inc. is an advanced renewable fuels and biochemicals company based in Cupertino, California, USA. Operating in the energy sector, the company is focused on the production and sale of biofuels, such as ethanol and biodiesel, alongside essential biochemicals. Aemetis primarily operates through two key segments: North America, which concentrates on ethanol production, and India, specializing in biodiesel and refined glycerin manufacturing. Notably, the company has initiated several significant projects, including a biogas initiative to convert dairy waste into renewable natural gas and a cellulosic ethanol facility using agricultural waste as a feedstock. These projects align with Aemetis' strategic emphasis on sustainable, environmentally friendly practices and technology-driven innovation in the bioenergy space.
Industrial Organic Chemicals 157.16 29.40 2.52 11.53 2.54 354.67 81.80
1725 ISRG / Intuitive Surgical, Inc.
Intuitive Surgical, Inc., based in the United States, is a prominent pioneer in the field of robotic-assisted, minimally invasive surgery. Central to its portfolio is the renowned da Vinci Surgical System, which enhances surgical precision and dexterity while minimizing patient recovery times. Beyond its flagship technology, the company invests heavily in research and development to refine its existing systems and innovate new solutions that address complex surgical challenges. Key projects focus on expanding the applicability of robotics across a broader range of surgical procedures and enhancing the integration of advanced imaging and data analytics to improve surgical outcomes. These efforts underscore Intuitive Surgical's commitment to advancing the field of surgical robotics and expanding its market presence globally.
Mga Orthopedic, Prosthetic, at Surgical Appliances at Supplies 169,676.26 719.25 444.40 598.96 473.30 26.51 81.79
1727 CYRX / Cryoport, Inc.
Cryoport, Inc. is a United States-based company that operates primarily within the temperature-controlled logistics industry, providing comprehensive solutions to support the life sciences and biopharmaceutical sectors. The company specializes in the shipment of biological samples, pharmaceuticals, and other products that require cryogenic and refrigerated transportation. Cryoport uses advanced logistics management technology, specialty packaging, and vacuum insulated containers to maintain stringent temperature conditions. Key projects encompass collaborations with biotechnology firms and pharmaceutical companies for the secure transport of clinical trial materials and commercially viable biologic drugs globally. This service is crucial for the advancement and distribution of temperature-sensitive therapies and supports Cryoport’s mission to enhance healthcare through reliable biopharmaceutical supply chain solutions.
Mga Paghahanda sa Parmasyutiko 444.78 16.80 8.08 12.35 8.86 39.59 81.79
1728 GRCE / Grace Therapeutics, Inc.
Acasti Pharma Inc. is a biopharmaceutical company based in Canada, primarily engaged in the research and development of novel therapies that address significant medical conditions through scientific and clinical innovation. The company's flagship project involves the development of CaPre, an omega-3 phospholipid therapeutic aimed at treating severe hypertriglyceridemia, a condition characterized by abnormally high levels of triglycerides in the bloodstream. This therapeutic candidate seeks to leverage unique lipid-regulating properties to improve cardiovascular health. Acasti Pharma's strategic focus extends to advancing its pipeline through rigorous clinical trials and expanding its portfolio through strategic alliances and acquisitions, positioning itself crucially within the biopharmaceutical sector focused on lipid management therapies.
Mga Paghahanda sa Parmasyutiko 41.90 13.12 11.11 12.11 3.03 299.75 81.77
1730 IOT / Samsara Inc. Computer Integrated Systems Design 20,518.15 63.00 38.38 48.37 36.14 33.86 81.76
1732 MPTI / M-tron Industries, Inc. Mga Electronic na Bahagi, Hindi Nauuri sa Ibang Lugar 131.52 70.35 67.67 68.34 44.98 52.92 81.76
1733 REKR / Rekor Systems, Inc.
Rekor Systems, Inc., based in the United States, operates primarily within the technology sector, focusing on intelligent infrastructure through artificial intelligence (AI) and machine-learning-enhanced solutions. The company specializes in traffic management, public safety, and electronic toll collection systems that offer real-time roadway intelligence. Key projects include the deployment of its AI-driven vehicle recognition software across several U.S. states, enhancing vehicle detection and analysis for improved traffic flow and safety measures. Furthermore, Rekor's technology extends to smart city initiatives, where it integrates its systems with existing urban infrastructure to promote efficiency, compliance, and security. Through these initiatives, Rekor Systems demonstrates its commitment to innovating core infrastructure systems, facilitating more informed decision-making and resource allocation in government sectors.
Communications Equipment, Not Elsewhere Classified 136.26 4.20 4.04 4.08 1.12 266.02 81.75
1736 TGTX / TG Therapeutics, Inc.
TG Therapeutics, Inc. is a biopharmaceutical company based in the United States, primarily involved in the development and commercialization of therapies for the treatment of hematologic malignancies and autoimmune diseases. The company's flagship projects include innovative monoclonal antibodies and novel small molecules targeting specific cancer and immune cells. Notably, TG Therapeutics has focused on multitherapeutic approaches, such as the combination of ublituximab and umbralisib, designed to improve patient outcomes in diseases like chronic lymphocytic leukemia and non-Hodgkin's lymphoma. Their commitment to advancing targeted treatment options encapsulates the company's core mission to enhance the quality of life for patients suffering from severe and life-threatening diseases through groundbreaking medical solutions.
Mga Paghahanda sa Parmasyutiko 4,306.08 57.75 11.11 42.84 29.33 45.99 81.75
1737 IMAB / I-Mab - Depositary Receipt (Common Stock)
I-Mab, based in China, operates as a clinical-stage biopharmaceutical company primarily involved in the discovery, development, and potential commercialization of innovative biologics in the therapeutic area of immuno-oncology and autoimmune diseases. As a player in the biotech industry, I-Mab stands out due to its robust pipeline that includes several late-stage assets and other drug candidates in various stages of clinical trials globally. Notably, the company is committed to addressing critical unmet medical needs by advancing a wave of novel therapies, focusing on bringing pioneering treatments to patients worldwide. The strategic deployment of its resources underscores its dedication to achieving milestones in biologic therapy innovations, exemplified by its continued progression to phase III clinical trials in some candidate drugs.
Mga Paghahanda sa Parmasyutiko 340.64 7.35 5.05 6.32 4.16 51.84 81.74
1739 DVN / Devon Energy Corporation
Devon Energy Corporation, based in the United States, operates primarily within the energy sector, focusing on oil and natural gas exploration and production. A prominent player in the industry, Devon Energy is known for its strategic asset base primarily concentrated in the Delaware Basin, a subset of the larger Permian Basin considered one of North America's most prolific oil and natural gas geographies. The company integrates technology and sustainability practices in its operations, aiming to increase recovery and efficiency while minimizing environmental impacts. Key projects include enhanced oil recovery initiatives and the development of shale resources, which position Devon Energy as a leader in the U.S. energy landscape, driving both growth and operational excellence in its pursuits.
Crude Petroleum at Natural Gas 22,923.50 69.30 33.33 45.98 36.10 27.30 81.73
1744 LQDA / Liquidia Corporation
Liquidia Corporation is a biopharmaceutical company based in the United States, specifically headquartered in Morrisville, North Carolina. It operates primarily within the healthcare sector, focusing on the development and commercialization of novel products for pulmonary arterial hypertension (PAH) and other diseases. Liquidia utilizes its proprietary PRINT technology, a particle engineering platform, to enhance the delivery and performance of existing therapeutics. A key project for the company is the development of LIQ861, an inhalation powder of treprostinil designed to enhance the treatment of PAH. Additionally, Liquidia is actively engaged in a legal battle over patents related to their technology, particularly against competitors seeking to use similar technologies. The company’s strategic initiatives are directed towards leveraging its platform for pipeline expansion and improving patient outcomes in its targeted therapeutic areas.
Mga Paghahanda sa Parmasyutiko 2,375.77 56.70 6.06 37.40 27.68 35.16 81.70
1745 DFLI / Dragonfly Energy Holdings Corp. Miscellaneous Electrical Machinery, Equipment, and Supplies 10.85 1.58 1.01 1.19 0.29 310.50 81.70
1748 RZLV / Rezolve AI PLC 10.50 4.04 6.25 3.74 66.60 81.68
1749 DT / Dynatrace, Inc.
Dynatrace, Inc., based in the United States, operates predominantly within the software industry, specifically focusing on intelligence software and services. The company is renowned for its advanced cloud software that helps businesses monitor, optimize, and scale application performance, infrastructure, and cloud environments. Key projects and services by Dynatetroitishly are centered around artificial intelligence for IT operations (AIOps), application security, and digital experience management, providing real-time analytics and automation to enhance operational efficiencies and cybersecurity measures. By integrating machine learning and full-stack observability, Dynatrace assists enterprises in managing complex digital ecosystems effectively, ensuring high performance and improved user experiences.
Naka-prepack na Software 15,266.81 73.50 52.52 63.76 50.60 26.01 81.68
1752 HRMY / Harmony Biosciences Holdings, Inc. Mga Paghahanda sa Parmasyutiko 2,122.57 73.50 31.31 51.56 36.89 39.76 81.67
1754 USIO / Usio, Inc. Functions Related to Depository Banking, Not Elsewhere Classified 39.05 5.78 4.04 4.93 1.48 234.24 81.65
1755 MRX / Marex Group plc 2,533.16 60.90 36.36 51.91 35.36 46.92 81.64
1762 LBTYA / Liberty Global Ltd.
Liberty Global Ltd., based in London, United Kingdom, operates as a multinational telecommunications company. It stands as one of the world’s leading converged video, broadband, and communication companies, primarily focusing on operations in Europe, including key markets like the United Kingdom, Switzerland, and Ireland. Liberty Global is involved in significant projects that enhance broadband penetration and network capacity, such as substantial upgrades to its infrastructure and the expansion of its gigabit-speed internet services. Additionally, the company actively engages in strategic acquisitions and partnerships to bolster its market presence and technological capabilities, aiming to leverage advancements in 5G technology and expand its offerings in mobile telephony and business-to-business telecommunications solutions.
Cable at Iba pang Pay Television Services 3,878.42 36.75 10.00 17.06 11.74 45.48 81.59
1767 ACN / Accenture plc
Accenture plc is a multinational professional services company headquartered in Dublin, Ireland. It operates primarily in the domain of IT services and consulting, positioning itself as a leader in digital, cloud, and security solutions across a broad range of industries. Noteworthy projects include collaborating with major global enterprises for digital transformations, implementing extensive cloud-based infrastructure solutions, and driving innovations in cybersecurity. Accenture's strategy involves leveraging its extensive global network, profound industry expertise, and advancements in areas such as artificial intelligence and machine learning to deliver comprehensive, end-to-end solutions that nurture business growth and operational efficiency. This strategic direction allows Accenture to maintain a competitive edge in a rapidly evolving digital landscape.
Mga Serbisyo sa Negosyo, Hindi Nauuri sa Ibang Lugar 161,961.31 390.60 242.40 332.96 259.97 28.00 81.57
1769 SION / Sionna Therapeutics, Inc. 1,086.54 47.25 32.32 39.27 24.62 59.50 81.56
1770 EE / Excelerate Energy, Inc. Pamamahagi ng Natural Gas 781.47 45.15 26.26 34.17 24.42 39.93 81.56
1775 EICCF / E Automotive Inc. 11.95 0.20 81.53
1776 DARE / Daré Bioscience, Inc. Mga Paghahanda sa Parmasyutiko 18.24 12.60 11.11 11.90 2.02 484.77 81.52
1778 OWL / Blue Owl Capital Inc. Payo sa Pamumuhunan 12,032.17 30.45 21.21 24.32 18.52 31.26 81.51
1782 CRCL / Circle Internet Group, Inc. Crude Petroleum at Natural Gas 30,161.92 294.00 84.84 191.25 131.98 44.90 81.50
1785 VREX / Varex Imaging Corporation Mga Electronic na Bahagi, Hindi Nauuri sa Ibang Lugar 479.56 24.15 10.10 17.75 11.55 53.66 81.49
1786 TALO / Talos Energy Inc.
Talos Energy Inc., based in the United States, operates as an independent oil and gas company primarily focused on offshore exploration and production. The company is involved in the acquisition, exploration, development, and production of oil and natural gas properties in the Gulf of Mexico. One of its key projects includes the Zama oil discovery in Mexico, which represents a significant portion of its portfolio. Talos Energy Inc. employs innovative techniques and technologies to optimize asset performance and has a strong commitment to safety and environmental stewardship. Through strategic partnerships and robust operational execution, Talos aims to enhance shareholder value while maintaining high environmental and safety standards in its operations.
Crude Petroleum at Natural Gas 1,725.61 21.00 9.09 13.07 9.88 32.33 81.49
1787 SARO / StandardAero, Inc. 8,860.12 42.00 32.32 36.72 26.49 38.62 81.49
1792 AAUC / Allied Gold Corporation 1,616.95 29.95 16.19 21.27 14.00 51.85 81.47
1793 WKSP / Worksport Ltd. Mga Bahagi at Accessory ng Sasakyan ng Motor 17.36 13.12 7.07 10.54 3.11 235.13 81.47
1797 GDDY / GoDaddy Inc.
GoDaddy Inc., based in the United States, operates predominantly in the internet services and infrastructure industry. As one of the largest domain registrars and web hosting companies worldwide, GoDaddy provides a variety of solutions that include domain registration, website hosting, website building tools, and online marketing services. Its key projects often focus on expanding digital real estate services, innovative customer support technologies such as the use of AI and automation, and strategic acquisitions to broaden its service portfolio. GoDaddy aims to empower a global community of customers by offering user-friendly, affordable tools to launch and grow their online presence. GoDaddy's commitment to expanding its offerings continuously evolves to meet the dynamic needs of the digital economy.
Computer Integrated Systems Design 20,594.77 262.50 151.50 194.58 148.31 31.19 81.45
1798 UPBD / Upbound Group, Inc. Pagrenta at Pagpapaupa ng Kagamitan, Hindi Nauuri sa Ibang Lugar 1,469.90 51.45 21.21 35.19 25.41 38.54 81.44
1800 OFIX / Orthofix Medical Inc.
Orthofix Medical Inc., based in the United States, operates within the healthcare sector, specifically focusing on medical devices and orthopedic products. The company specializes in designing, developing, and delivering innovative orthopedic and spine solutions that improve patient outcomes. Key projects and product lines include orthopedic fixation devices, bone growth therapies, and spinal therapy devices, which cater to the diverse needs of patients undergoing spinal and orthopedic surgeries. Orthofix Medical plays a critical role in its industry by providing advanced medical technologies that aid in bone and tissue repair, addressing a significant market in sports medicine, post-operative orthopedic care, and congenital deformities management. This strategic focus helps position Orthofix Medical as a leader in its field, contributing broadly to global healthcare solutions.
Mga Instrumento at Apparatus ng Surgical at Medikal 591.06 28.56 17.17 23.00 14.98 53.65 81.44
1805 MASI / Masimo Corporation
Masimo Corporation, based in the United States, operates primarily in the healthcare equipment industry, specializing in innovative noninvasive monitoring technologies. Renowned for its development of Signal Extraction Technology (SET®) that enhances pulse oximetry, Masimo offers products aimed at improving patient outcomes and reducing care costs. Key innovations include a wide array of patient monitoring systems, such as bedside and wearable technologies, along with connectivity solutions used across hospital settings. Among their significant projects is the Patient SafetyNet™ system, which helps to remotely monitor patient conditions and facilitate timely clinical interventions. Masimo also extends its technological expertise to brain and respiratory monitoring solutions, demonstrating a commitment to comprehensive patient healthcare advancements.
Electromedical at Electrotherapeutic Apparatus 7,589.72 220.50 171.70 190.86 139.71 36.61 81.42
1806 TW / Tradeweb Markets Inc. Security At Commodity Brokers, Dealers, Exchanges, At Serbisyo 26,323.41 220.50 131.30 159.75 123.36 29.50 81.41
1807 MX / Magnachip Semiconductor Corporation
Magnachip Semiconductor Corporation, headquartered in Luxembourg, primarily operates in the semiconductor industry. The company specializes in manufacturing and designing analog and mixed-signal semiconductor platform solutions, focusing on applications for consumer, computing, communications, and industrial markets. Key offerings include display solutions, such as OLED display drivers and power solutions, which encompass power management and converters for various electronic devices. Prominent for advancing OLED technology, Magnachip has engaged in strategic collaborations and partnerships aimed at expanding its market reach and enhancing its product portfolio. These efforts position Magnachip as an influential participant in the global semiconductor space, constantly innovating to meet the evolving demands of the digital and electronics sectors.
Mga Semiconductor at Mga Kaugnay na Device 113.26 5.78 5.05 5.36 3.15 70.27 81.40
1808 SLB / Schlumberger Limited
Schlumberger Limited, based in Houston, USA, operates primarily in the energy sector, focusing on oilfield services and equipment. As the world's leading provider in this industry, Schlumberfinger plays a crucial role in enabling efficiency and technological advancements in the extraction and management of energy resources globally. Key projects typically involve sophisticated technologies for drilling, reservoir characterization, well construction, and production optimization. The company's extensive research and development efforts are aimed at driving innovations in hydraulic fracturing, directional drilling, and real-time data management, positioning Schlumberger at the forefront of the energy transition movement toward more sustainable and responsible resource utilization. These initiatives underscore its commitment to addressing both the current and evolving needs of the global energy market.
Mga Serbisyo sa Larangan ng Langis at Gas, Hindi Nauuri sa Ibang Lugar 49,770.84 66.15 36.36 46.30 36.84 25.81 81.40
1812 LFWD / Lifeward Ltd. Mga Orthopedic, Prosthetic, at Surgical Appliances at Supplies 9.94 10.50 1.01 5.61 0.63 783.74 81.38
1815 OPRT / Oportun Financial Corporation
Oportun Financial Corporation, based in the United States, operates primarily in the financial services industry, specializing in providing affordable and credit-building loans to individuals with limited credit history. The company leverages advanced data analytics and technology to offer personal and auto loans that not only meet the immediate financial needs of its consumers but also aim to promote financial inclusion and foster long-term financial health among underserved communities. Key projects include the continued expansion of their lending products and enhancing digital platforms to improve accessibility and customer experience. Oportun Financial Corporation's innovative approach ensures a blend of social responsibility with robust financial practices, reflecting its commitment to supporting economically disadvantaged groups while maintaining sustainable business growth.
Mga Serbisyo sa Pananalapi 307.84 11.55 7.27 9.64 6.61 45.82 81.37
1825 CGC / Canopy Growth Corporation
Canopy Growth Corporation, based in Canada, operates at the forefront of the global cannabis industry. Established as a medical marijuana producer, the company has expanded its reach to include a wide array of cannabis products, including dried flower, oil, capsules, and hemp. Key projects and initiatives include their partnership with Constellation Brands to delve into cannabis-infused beverages, and significant investments in research and development to innovate and scale up their product line. The firm focuses heavily on both the recreational and medical cannabis markets, leveraging state-of-the-art growing and production facilities to maintain and enhance their market position. Canopy Growth's strategy includes expanding its international presence, particularly in regions with evolving cannabis regulations.
Bahan Kimia Obat dan Produk Botani 368.24 6.05 1.16 2.72 1.80 51.43 81.33
1828 PRO / PROS Holdings, Inc.
PROS Holdings, Inc., headquartered in the United States, operates primarily within the technology sector, focusing on providing AI-based solutions that power commerce in the digital economy. The company specializes in cloud-based platforms designed to optimize shopping and selling experiences across industries through real-time, AI-driven pricing and revenue management. Key projects include the development of dynamic pricing science which personalizes pricing at the point of transaction. Their technology aids businesses in accurately forecasting and delivering appropriate pricing strategies, thus enhancing profit maximization and customer satisfaction. PROS Holdings has positioned itself as a leader in facilitating e-commerce through innovation and cutting-edge software solutions that adapt to the complexities of the global market.
Mga Serbisyo sa Computer Programming 743.79 37.80 18.18 26.23 15.50 69.22 81.33
1831 RVLPQ / RVL Pharmaceuticals plc
RVL Pharmaceuticals plc is a pharmaceutical company headquartered in Dublin, Ireland. The company primarily operates in the healthcare sector, focusing on the development and commercialization of products for ophthalmic diseases. A key product developed by RVL Pharmaceuticals is Upneeq, a prescription eye drop specifically aimed at treating acquired blepharoptosis, or droopy eyelid, in adults. This product represents the culmination of the company’s targeted approach in the specialized field of eye health, leveraging innovative research and development strategies to address unmet medical needs. RVL Pharmaceuticals continues to invest in clinical research to potentially expand the indications of Upneeq and enhance its product pipeline through strategic initiatives and partnerships within the pharmaceutical industry.
Mga Paghahanda sa Parmasyutiko 0.00 81.31
1832 ITGR / Integer Holdings Corporation
Integer Holdings Corporation, based in the United States, operates primarily in the medical device industry. As a leading manufacturer of medical devices and components, Integer specializes in producing cardiovascular, neuromodulation, portable medical, and other medical technologies. Key projects typically involve the design, development, and manufacturing of devices that are integral in cardiac rhythm management, neuromodulation procedures, and vascular and orthopedic applications. Integer’s operations are substantial, encompassing research and development initiatives aimed at advancing medical device technology and enhancing patient outcomes. The company’s commitment to innovation is reflected in their ongoing projects which include partnerships with larger healthcare companies to produce state-of-the-art medical solutions.
Electromedical at Electrotherapeutic Apparatus 3,779.21 162.75 133.32 143.69 107.87 33.22 81.31
1837 INTU / Intuit Inc.
Intuit Inc. is a multinational financial software company headquartered in the United States. Operating primarily within the software industry, Intuit specializes in creating financial, accounting, and tax preparation tools for small businesses, accountants, and individuals. One of its flagship products, QuickBooks, provides robust accounting solutions tailored to small and medium-sized enterprises, while TurboTax is widely utilized for tax preparation by individuals in the U.S. Intuit is also known for its innovative project, Mint, a personal financial management service. Across its various platforms, Intuit emphasizes cloud-based applications and artificial intelligence technologies to streamline financial processes and provide real-time data insights, thereby supporting efficient management and planning for its users.
Naka-prepack na Software 186,093.00 984.90 565.60 837.37 667.00 25.51 81.28
1838 BLTE / Belite Bio, Inc - Depositary Receipt (Common Stock)
Belite Bio, Inc, based in the United States, is a biopharmaceutical company focused on the discovery and development of novel therapeutics for the treatment of age-related and orphan retinal diseases. The company's strategic emphasis is on addressing significant unmet medical needs in ocular diseases that cause blindness, such as Stargardt disease and age-related macular degeneration. Notably, Belite Bio has several key projects in various stages of clinical development aimed at creating innovative solutions that can prevent, manage, or treat these debilitating eye diseases. This focus on retina-related conditions positions Belite Bio as a specialty player in the biotechnology industry, contributing to the advancement of ocular medical care.
2,070.38 115.50 80.80 95.62 63.03 51.71 81.28
1839 SLGN / Silgan Holdings Inc.
Silgan Holdings Inc., based in Stamford, Connecticut, USA, operates primarily in the packaging industry. The company specializes in the production of metal and plastic containers primarily used for food and consumer goods. It is segmented into three main divisions: Silgan Containers, which is the largest manufacturer of metal food containers in North America; Silgan Closures, focusing on metal and plastic closure solutions; and Silgan Plastic Containers, known for its high-density polyethylene and polyethylene terephthalate containers for personal and healthcare products. Key projects often involve technological innovations in packaging such as enhancements in barrier technologies to extend product shelf life and the development of more sustainable packaging solutions to meet environmental regulations and customer preferences.
Metal Cans 5,025.13 70.35 48.28 61.18 46.92 30.39 81.27
1845 CERS / Cerus Corporation
Cerus Corporation, based in the United States, operates predominantly in the biotechnology sector, focusing on the development and commercialization of the INTERCEPT Blood System. This innovative system is designed to enhance blood safety by reducing the risk of transfusion-transmitted infections through the inactivation of pathogens present in donated blood. The primary technologies involved target platelets, plasma, and red blood cells, catering to a global need for safe blood supplies for transfusions. Cerus' key projects center around expanding the adoption of the INTERCEPT treatment system across blood centers worldwide, while continuously advancing research to broaden its applicability to more blood components and meet various regulatory standards for transfusion medicine. The company's efforts extend into multiple international markets, emphasizing both technological innovation and strategic partnerships to drive broader utilization and acceptance of their blood safety technologies.
Mga Instrumento at Apparatus ng Surgical at Medikal 250.02 5.25 4.04 4.76 1.31 264.75 81.22
1846 AHCO / AdaptHealth Corp. Home Health Care Services 1,254.02 16.80 10.60 13.39 9.49 41.22 81.22
1852 SMWB / Similarweb Ltd.
Similarweb Ltd., based in Israel, operates within the analytics and digital intelligence sector, providing advanced web analytics services that allow businesses to gauge web traffic and other digital metrics. The company's offerings empower users to observe and analyze various digital activities, benefitting marketers, researchers, and executives by delivering insights on performance, competitors, and market trends. Their key projects usually involve providing sector-specific analysis, tracking competitor activities, and refining digital strategies for clients across multiple industries. Similarweb distinguishes itself through its expansive dataset and sophisticated algorithms, which enable comprehensive visibility into digital behavior, thus providing strategic insights that aid businesses in making data-driven decisions in today's digital economy.
Computer Programming, Pagproseso ng Data, At Iba Pang Serbisyong Kaugnay ng Computer 881.64 17.85 10.10 13.64 10.39 31.24 81.18
1856 BV / BrightView Holdings, Inc.
BrightView Holdings, Inc., based in the United States, operates primarily in the landscape services industry. As a major player in this sector, the company provides a comprehensive range of services including landscape maintenance, design, development, and enhancement for commercial, institutional, and residential clients. BrightView distinguishes itself with high-profile projects such as maintaining attractions like the Olympic Park and professional sports venues. Offering sustainability-oriented solutions, such as water management and energy-efficient design, demonstrates BrightView’s commitment to environmental stewardship. Leveraging a national footprint, the company frequently engages in strategic acquisitions to expand its market reach and service capabilities, thereby reinforcing its position as a leader in the landscaping industry.
Agricultural Services 1,368.00 25.20 13.64 19.60 14.40 36.10 81.17
1857 EPRX / Eupraxia Pharmaceuticals Inc. 190.94 9.09 6.56 8.09 5.36 51.01 81.16
1860 PUMP / ProPetro Holding Corp.
ProPetro Holding Corp., based in the United States, is a prominent service provider in the oilfield services industry, primarily focusing on the North American unconventional shale market. The company specializes in hydraulic fracturing, cementing, and coiled tubing services tailored for major oil and natural gas basins. One of its key projects involves providing integrated hydraulic fracturing services to enhance the production of hydrocarbons, which caters to the evolving needs of the Permian Basin, one of the most productive oil regions in the US. ProPetro emphasizes innovations in hydraulic fracturing technology and efficiency, aiming to deliver environmentally conscious and cost-effective solutions, which align with the industry's push towards sustainability and reduced operational footprint.
Mga Serbisyo sa Larangan ng Langis at Gas, Hindi Nauuri sa Ibang Lugar 530.23 10.50 6.06 7.76 5.10 51.92 81.16
1865 PCTY / Paylocity Holding Corporation
Paylocity Holding Corporation is a prominent player in the United States payroll and human resource technology industry. This company specializes in cloud-based HR and payroll software solutions, primarily serving small and mid-sized businesses across various sectors. Paylocity provides a comprehensive suite of software services including payroll processing, human capital management, time and labor management, and benefits administration, which neatly integrate with other essential business applications. As an innovator in its field, Paylocity often emphasizes leveraging advanced technologies such as artificial intelligence and machine learning to enhance user experience and improve the efficiency of HR operations, positioning itself as a forward-thinking leader in cloud-based workforce solutions.
Naka-prepack na Software 9,922.14 283.50 196.95 227.83 179.23 27.13 81.14
1869 ANIX / Anixa Biosciences, Inc.
Anixa Biosciences, Inc., headquartered in the United States, operates in the biotechnology sector, primarily focusing on the development of innovative approaches in cancer treatment and infectious disease prevention. The company is engaged in advancing a diverse portfolio of projects including proprietary cancer vaccines and therapies that modulate key immune responses. Notably, Anixa’s research initiatives target breast cancer with a vaccine designed to prevent the recurrence of triple-negative breast cancer, a particularly aggressive form of the disease. Additionally, the company explores the therapeutic potential of chimeric endocrine receptor technology. Anixa is also developing a nasal vaccine for COVID-19, highlighting its dedication to addressing significant global health challenges. The company’s projects often involve collaborations with leading academic institutions and research organizations to facilitate the transition from scientific discovery to clinical application.
Mga Paghahanda sa Parmasyutiko 96.63 10.50 7.07 9.18 2.99 206.00 81.11
1870 NAUT / Nautilus Biotechnology, Inc. Mga Instrumentong Analitikal sa Laboratory 85.89 2.62 2.52 2.55 0.68 275.00 81.11
1871 BKSY / BlackSky Technology Inc. Kagamitan sa Pag-broadcast sa Radyo at Telebisyon at Komunikasyon 606.82 32.55 17.17 24.82 17.56 41.50 81.11
1874 SHAK / Shake Shack Inc.
Shake Shack Inc., based in the United States, operates primarily in the fast-casual restaurant industry, specializing in high-quality burgers, hot dogs, and shakes. Founded by Danny Meyer's Union Square Hospitality Group in 2004, it originated from a hot dog cart in Manhattan's Madison Square Park. The company is noted for its commitment to premium ingredients and innovative menu offerings. Beyond its core offerings, it has increasingly focused on sustainability and technological enhancements in its operations, such as implementing digital ordering kiosks and a mobile ordering app. Shake Shack has pursued global expansion, with locations across the United States and numerous international markets, adapting its menu to local tastes and preferences as part of its growth strategy.
Restaurants, Dining, Eating And Drinking Places 4,265.86 170.10 111.10 139.48 106.00 31.50 81.10
1877 CAN / Canaan Inc. - Depositary Receipt (Common Stock)
Canaan Inc., headquartered in China, is a prominent player in the technology sector, primarily specialized in the research, development, and sales of integrated circuit final system products, including application-specific integrated circuits (ASIC). These specialized chips are heavily utilized in cryptocurrency mining, with the company being among the pioneers in developing ASICs tailored for blockchain mining operations. Canaan Inc. has solidified its presence by expanding its offerings to include AI chip solutions, further diversifying its technological impact. The company’s most notable endeavors include establishing reliable supply chains for its advanced hardware and venturing into AI-driven applications, which synergistically enhance its core operations in the cryptocurrency mining field.
Mga Serbisyo sa Pananalapi 370.30 4.20 1.52 2.53 0.74 239.94 81.09
1878 AVXL / Anavex Life Sciences Corp.
Anavex Life Sciences Corp. is a biopharmaceutical company based in the United States, primarily engaged in the development of drug candidates to treat neurodegenerative and neurodevelopmental disorders such as Alzheimer's disease, Parkinson's disease, and Rett syndrome through its proprietary compounds. The company's key projects include the development of ANAVEX®2-73 (blarcamesine), which has entered various stages of clinical trials targeting multiple neurological conditions. Employing its SIGMACEPTOR™ Discovery Platform, Anavex Life Sciences focuses on exploiting the potential of sigma-1 and muscarinic receptors to modulate disease processes. This innovative approach underpins the company's strategy to pioneer treatments that address the complex pathophysiology of central nervous system disorders, positioning Anavex as a leader in the biopharmaceutical industry focused on neurological diseases.
Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 823.37 48.30 15.15 35.02 9.64 263.28 81.09
1885 PTEN / Patterson-UTI Energy, Inc.
Patterson-UTI Energy, Inc., based in the United States, operates primarily within the oilfield services industry, delivering a comprehensive suite of services and equipment to oil and natural gas producers. The company is predominantly known for its land-based drilling rig operations, which are among the largest in the U.S., featuring a significant fleet of high-specification rigs designed for the technical demands of today’s drilling activities. Patterson-UTI Energy also provides pressure pumping services, directional drilling solutions, and other ancillary services to its clients, enabling enhanced extraction efficiency and operational safety. These offerings position the company as a crucial provider in the energy sector, supporting both conventional and unconventional resource development projects across North America.
Drilling Oil and Gas Wells 2,238.97 10.50 6.31 7.69 5.81 32.30 81.01
1886 CVRX / CVRx, Inc. Mga Instrumento at Apparatus ng Surgical at Medikal 204.85 14.70 9.09 11.83 7.85 51.01 81.01
1887 LBTYB / Liberty Global Ltd.
Liberty Global Ltd., based in London, United Kingdom, operates as a multinational telecommunications company. It stands as one of the world’s leading converged video, broadband, and communication companies, primarily focusing on operations in Europe, including key markets like the United Kingdom, Switzerland, and Ireland. Liberty Global is involved in significant projects that enhance broadband penetration and network capacity, such as substantial upgrades to its infrastructure and the expansion of its gigabit-speed internet services. Additionally, the company actively engages in strategic acquisitions and partnerships to bolster its market presence and technological capabilities, aiming to leverage advancements in 5G technology and expand its offerings in mobile telephony and business-to-business telecommunications solutions.
Cable at Iba pang Pay Television Services 2,193.93 37.96 10.33 17.26 11.53 50.48 81.01
1888 ACHR / Archer Aviation Inc. Sasakyang panghimpapawid 5,733.70 18.90 4.54 12.94 8.95 44.59 81.00
1889 UNM / Unum Group
Unum Group is a United States-based provider of financial protection benefits primarily through the workplace. Headquartered in Chattanooga, Tennessee, the company operates in the insurance industry, offering a range of products including disability, life, accident, critical illness, dental, and vision insurance to help protect individuals and their families. Unum Group serves millions of consumers in the U.S. and U.K. and focuses on supporting not only individual workers but also their family members, through comprehensive benefits solutions tailored to changing workforce dynamics. Key projects initiated by Unum revolve around innovations in disability benefits management, integrated digital experiences for customers, and expansion of voluntary benefits in response to growing employee demand. These strategic initiatives demonstrate their commitment to enhancing customer experiences while adapting to new market challenges and opportunities.
Accident and Health Insurance 12,025.59 113.40 79.79 94.86 69.86 35.79 80.99
1892 BDRX / Biodexa Pharmaceuticals Plc - Depositary Receipt (Common Stock)
Biodexa Pharmaceuticals Plc is a biotechnological firm based in the United Kingdom, primarily engaged in the pharmaceuticals industry. The company specializes in the research, development, and commercialization of innovative drug therapies. A significant focus of Biodexa Pharmaceuticals is on developing treatments for diseases that currently have limited therapeutic options. Key projects include advanced-stage clinical trials for new oncology drugs, which aim to address various forms of cancer with novel mechanisms of action. Additionally, the company has made strides in the neurodegenerative disease space, emphasizing breakthrough treatments for conditions such as Alzheimer's and Parkinson's disease. Biodexa Pharmaceuticals continues to expand its research capabilities and forge strategic partnerships to accelerate drug development and access global markets.
189.00 181.80 183.60 5.60 3,214.08 80.98
1896 EVTL / Vertical Aerospace Ltd. Sasakyang panghimpapawid 411.53 15.75 2.02 10.37 4.86 112.94 80.97
1897 QTTB / Q32 Bio Inc. Mga Paghahanda sa Parmasyutiko 21.10 21.00 4.04 10.20 1.71 489.60 80.97
1905 SSKN / STRATA Skin Sciences, Inc.
STRATA Skin Sciences, Inc., based in the United States, operates primarily in the medical technology industry, focusing on dermatological treatments. The company specializes in the development and commercialization of therapeutic and diagnostic devices that address various skin conditions, most notably psoriasis, vitiligo, and related dermatoses. STRATA's flagship products include the XTRAC excimer laser and VTRAC lamp systems, which are designed for targeted phototherapy treatment, enhancing patient outcomes by delivering high-dose, high-intensity ultraviolet light directly to affected areas. Their innovative approaches and specialized equipment cater to a substantial demand within both clinical settings and private practices, positioning STRATA as a key player in medical dermatology solutions.
Mga Instrumento at Apparatus ng Surgical at Medikal 10.09 12.60 4.04 8.16 2.38 237.26 80.93
1909 PHGE / BiomX Inc. Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 14.27 22.05 16.16 18.87 0.54 3,413.31 80.91
1916 MYPS / PLAYSTUDIOS, Inc. Naka-prepack na Software 121.06 5.25 1.52 2.93 0.97 203.38 80.87
1917 INO / Inovio Pharmaceuticals, Inc.
Inovio Pharmaceuticals, Inc. is a biotechnology firm based in the United States that primarily focuses on the discovery, development, and commercialization of synthetic DNA products for treating infectious diseases, cancer, and sexually transmitted diseases. Notably, Inovio has been active in developing vaccine candidates for COVID-19 and HPV-related cervical cancer. One of its key projects includes INO-4800, a DNA vaccine candidate for COVID-19, which has advanced to late-stage clinical trials. The company employs its proprietary DNA medicine platform, which has the potential to activate the immune system in a targeted approach against specific diseases. Inovio's work in the biotech industry underscores its commitment to innovating therapies that can address unmet medical needs globally.
Mga Paghahanda sa Parmasyutiko 87.02 13.65 1.82 7.62 2.37 221.35 80.87
1918 CODI / Compass Diversified
Compass Diversified, based in the United States, is a diversified global holding company that actively manages a portfolio of middle-market businesses across a variety of industries. Operating with a long-term, buy-and-hold strategy, the company focuses on acquiring profitable companies in sectors such as branded consumer, niche industrial, and healthcare. Key projects typically involve leveraging the company's robust capital resources and management expertise to enhance the operational efficiency and market reach of its subsidiaries. Noteworthy among its business model is the emphasis on acquiring controlling interests and working closely with these companies to drive growth and profitability through strategic innovation and operational improvements. This strategy has allowed Compass Diversified to sustain a steady growth trajectory while also distributing attractive returns to its shareholders.
Household Furniture 35.70 18.18 26.52 7.50 253.60 80.87
1920 BRKR / Bruker Corporation
Bruker Corporation, based in the United States, operates predominantly within the scientific instruments industry. It specializes in developing and manufacturing advanced instrumentation for a range of applications in the life sciences, pharmaceuticals, and materials science sectors. Key projects involve pioneering technologies in mass spectrometry, magnetic resonance, and analytical X-ray systems. Bruker's innovation extends to providing systems and solutions that enable significant advancements in research methodologies, therapeutic development, and industrial quality control. This focus on high-precision instruments positions Bruker as a leader in the scientific community, continuously contributing to progress in comprehensive analytical methods and diagnostic techniques. The company upholds a commitment to technical excellence and market leadership through ongoing research and development initiatives.
Mga Instrumentong Analitikal sa Laboratory 5,148.34 68.25 30.30 45.93 33.98 35.24 80.86
1927 PRLD / Prelude Therapeutics Incorporated Mga Paghahanda sa Parmasyutiko 68.86 5.25 1.01 3.57 1.21 193.39 80.84
1929 MNR / Mach Natural Resources LP
Mach Natural Resources LP is a United States-based company that operates in the oil and gas sector. The company is engaged in the exploration, development, and production of natural resources, with a particular focus on oil and natural gas.
Crude Petroleum at Natural Gas 1,683.93 26.25 21.21 23.26 14.23 63.43 80.83
1930 AMPL / Amplitude, Inc. 1,500.83 18.90 13.13 15.98 11.43 39.87 80.83
1939 CHRD / Chord Energy Corporation
Chord Energy Corporation, headquartered in the United States, is a prominent player in the oil and natural gas industry. Established through the 2022 merger between Whiting Petroleum Corporation and Oasis Petroleum, the company operates primarily in the Williston Basin of North Dakota and Montana. Focused on the development, production, and exploration of crude oil, natural gas, and natural gas liquids, Chord Energy is recognized for its operational efficiency and sustainable practices. The company's key projects are geared towards maximizing production from its extensive acreage in the Williston Basin while also advancing methods for reducing its environmental impact and enhancing the reliability of its operations.
Crude Petroleum at Natural Gas 6,331.60 175.35 106.05 138.97 109.89 26.86 80.80
1941 NRDS / NerdWallet, Inc.
NerdWallet, Inc., based in the United States, operates within the personal finance industry, offering a broad array of financial guidance and tools. Established with the mission to provide clear and useful financial advice, NerdWallet has developed a comprehensive platform catering to various financial decisions including credit cards, banking, investing, mortgages, and insurance. Key projects center around online financial education while integrating personalized management tools to assist in financial decision-making. The company's innovative approach harnesses both user-friendly digital interfaces and data-driven insights to simplify financial choices for consumers, thereby empowering them to achieve their personal financial goals. Through its expansive online presence, NerdWallet successfully positions itself as a trusted advisor in the financial sector.
Mga Serbisyo sa Pagproseso ng Computer at Paghahanda at Pagproseso ng Data 777.05 17.85 12.12 14.79 10.34 43.18 80.80
1942 LENZ / LENZ Therapeutics, Inc. 1,100.96 63.00 36.36 50.71 38.63 31.27 80.78
1943 SRZN / Surrozen, Inc. Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 104.43 44.10 32.32 37.74 12.18 209.73 80.78
1950 RYAN / Ryan Specialty Holdings, Inc. Mga Ahente ng Insurance, Broker, at Serbisyo 7,185.42 94.50 60.60 75.76 56.53 34.04 80.76
1953 EDU / New Oriental Education & Technology Group Inc. - Depositary Receipt (Common Stock)
New Oriental Education & Technology Group Inc., based in Beijing, China, is a prominent player in the private educational services industry. The company primarily focuses on providing a wide range of educational programs and services, including test preparation, language training, and cultural exchange services, to students across China. Key projects include K-12 after-school tutoring, overseas test preparation courses, and online educational platforms. Amid changes in China's regulatory environment targeting the private education sector, New Oriental has been adapting its business model to focus more on non-academic and adult education services, along with expanding its offerings through technology-driven platforms and overseas education services. These strategic adjustments aim to align with regulatory requirements and market demands, ensuring sustained growth in a dynamically evolving educational landscape.
Mga Serbisyong Pang-edukasyon 101.12 38.18 61.20 47.98 27.56 80.75
1955 VRTX / Vertex Pharmaceuticals Incorporated
Vertex Pharmaceuticals Incorporated, based in the United States, operates chiefly within the biotechnology industry, focusing on developing and commercializing therapies for serious diseases. Renowned for its significant advances in cystic fibrosis (CF) treatments, Vertex has successfully brought several groundbreaking medications to market that enhance the quality of life for patients with this genetic disorder. Besides its flagship CF products, the company actively expands its research and development pipeline across various other therapeutic categories including sickle cell disease, beta thalassemia, and pain management. Vertex's strategic initiatives aim to leverage its expertise in small molecule drug development to explore potential treatments in additional diseases with significant unmet medical needs.
Mga Paghahanda sa Parmasyutiko 100,218.43 655.20 333.30 491.74 391.02 25.76 80.75
1959 PRTA / Prothena Corporation plc
Prothena Corporation plc is a biotechnology company based in Ireland, primarily engaged in the development of treatments for neurodegenerative and other protein misfolding diseases. The company focuses on the discovery and development of novel antibodies targeting both well-established and newly identified protein targets implicated in these diseases. Key projects include the development of potential therapies for conditions such as AL amyloidosis, Parkinson's disease, and Alzheimer's disease. Noteworthy among its pipeline is birtamimab, designed for the treatment of AL amyloidosis, and prasinezumab, aimed at slowing the progression of Parkinson's disease. Prothena's approach combines proprietary protein immunotherapy technology with strategic collaborations aimed at accelerating the development of its therapeutic candidates.
Mga Paghahanda sa Parmasyutiko 441.41 85.05 4.04 26.52 8.20 223.61 80.73
1962 PAVM / PAVmed Inc. Mga Instrumento at Apparatus ng Surgical at Medikal 9.78 19.95 4.04 11.73 0.49 2,318.06 80.72
1964 SEAL.PRB / Seapeak LLC - Preferred Stock Transportasyong Tubig 80.71
1967 MAX / MediaAlpha, Inc. Mga Serbisyo sa Negosyo, Hindi Nauuri sa Ibang Lugar 596.15 25.20 13.13 17.26 10.57 63.25 80.71
1970 TRGP / Targa Resources Corp.
Targa Resources Corp., based in the United States, is a leading provider in the midstream natural gas and natural gas liquids (NGL) industry. The company primarily engages in gathering, compressing, treating, processing, and selling natural gas and NGLs, along with storing, fractionating, and transporting these products. Notable for its strategic footprint, Targa operates major assets including expansive gas gathering networks and processing plants mainly in regions like the Permian Basin and Bakken Shale. Key projects that underscore its significant operational scale include the Grand Prix NGL Pipeline and the Badlands operations, which together enhance its ability to efficiently manage and distribute hydrocarbon products across key markets, thereby supporting robust infrastructure growth and energy supply.
Paghahatid ng Natural Gas 36,153.86 252.00 160.02 209.55 167.76 24.86 80.68
1976 CORT / Corcept Therapeutics Incorporated
Corcept Therapeutics Incorporated, based in the United States, operates primarily in the biopharmaceutical industry. The company focuses on the development and commercialization of medications for severe metabolic, oncologic, and psychiatric disorders. Corcept has made significant strides particularly in the treatment of Cushing's syndrome, a disorder resulting from prolonged exposure to high levels of the hormone cortisol, with its flagship product, Korlym®, being the first FDA-approved medication for this condition. Additionally, the company is actively engaged in a robust clinical development program, seeking to leverage its proprietary technology for the modulation of glucocorticoid receptor (GR) and the development of other novel therapeutics. This research-intensive approach underscores Corcept's commitment to innovative treatments that address underserved markets and complex medical needs.
Mga Paghahanda sa Parmasyutiko 7,340.68 152.25 122.21 137.19 69.72 96.74 80.65
1977 EQIX / Equinix, Inc.
Equinix, Inc., based in the United States, operates primarily in the data center and colocation industry. It stands as a pivotal player providing a broad range of services designed to enable global interconnection and data exchange between organizations. Equinix’s key projects typically involve expanding its global platform of high-performance data centers, which currently spans across multiple continents including North America, Europe, Asia-Pacific, and South America. The company focuses on enhancing digital infrastructure through innovative projects such as the development of the Equinix Fabric platform, which facilitates direct and secure interconnection between its vast ecosystems of customers. This strategic initiative supports both existing IT and emerging technologies like edge computing, contributing significantly to its widespread utility and business growth.
Mga Trust sa Pamumuhunan sa Real Estate 76,850.45 1,260.00 812.04 979.48 786.19 24.73 80.64
1982 SNTI / Senti Biosciences, Inc. Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 38.72 15.75 12.12 13.77 1.47 830.41 80.63
1985 GT / The Goodyear Tire & Rubber Company
The Goodyear Tire & Rubber Company, based in the United States, is a predominant actor in the global tire industry, renowned for its innovative and comprehensive range of tire products designed for various types of vehicles including automobiles, trucks, buses, aircraft, motorcycles, and earth-moving machinery. Established in 1898, Goodyear has expanded its presence to a global scale, consistently focusing on advancements in tire technology and sustainable solutions. Key projects involve the development of environmentally-friendly tires and advanced tire management systems that integrate digital models to enhance vehicle efficiency and safety. Goodyear's commitment to innovation is also evident in its ventures into new rubber products, maintaining a significant influence on both automotive and related industries globally.
Tires and Inner Tubes 2,425.28 13.88 9.09 11.03 8.48 30.11 80.61
1987 VRCA / Verrica Pharmaceuticals Inc. Mga Paghahanda sa Parmasyutiko 51.78 21.00 10.10 15.30 5.60 173.70 80.60
1988 BBIO / BridgeBio Pharma, Inc.
BridgeBio Pharma, Inc., based in the United States, operates within the biotechnology sector, focusing primarily on genetic diseases and genetically validated targets. Since its inception, the company has dedicated itself to the development of medicines aimed at treating grievous genetic diseases by leveraging advances in genetic understanding. BridgeBio engages in various key projects across its pipeline, including therapies targeting conditions such as familial adenomatous polyposis and achondroplasia. The company embraces a comprehensive approach by collaborating with academic institutions to accelerate drug discovery and development processes, aiming to translate genetic insights into clinically actionable solutions for patients suffering from severe genetic disorders.
Mga Paghahanda sa Parmasyutiko 9,894.58 99.75 42.42 64.69 51.76 25.03 80.60
1989 FWONA / Formula One Group
Formula One Group, based in the United Kingdom, operates at the pinnacle of the motorsports industry, overseeing the globally-renowned Formula One World Championship. As the entity responsible for the promotion of the championship, the management and exploitation of its commercial rights, Formula One Group plays a central role in shaping the global motorsport landscape. Its key projects focus on enhancing the racing spectacle, increasing global viewership, and leveraging technological advancements to improve race safety and efficiency. The company continually explores avenues for digital expansion, including the development of digital platforms to better engage with fans and increase revenue streams from broadcasting and sponsorship deals, ensuring it remains at the forefront of sporting entertainment globally.
Mga Istasyon ng Broadcasting sa Telebisyon 24,502.40 141.75 99.99 115.67 90.12 28.35 80.60
1997 S / SentinelOne, Inc.
SentinelOne, Inc., based in the United States, operates primarily in the cybersecurity industry, providing cutting-edge solutions aimed at defending against a diverse range of cyber threats. The company is renowned for its autonomous AI-powered platform, which is designed to detect, respond to, and prevent cyber breaches in real-time. A crucial project underpin their technical portfolio is the Singularity Platform, which unifies endpoint protection, detection, response, and threat hunting with a singular AI-driven engine across diverse environments. This innovative approach facilitates comprehensive visibility and rapid mitigation of threats, positioning SentinelOne as a distinctive player in the cybersecurity sector focused on leveraging machine learning to enhance security protocols.
Naka-prepack na Software 6,264.06 37.80 15.15 23.41 18.86 24.14 80.53
2014 TMDX / TransMedics Group, Inc. Electromedical at Electrotherapeutic Apparatus 3,913.21 183.75 124.23 154.02 114.96 33.98 80.44
2017 ADIL / Adial Pharmaceuticals, Inc. Mga Paghahanda sa Parmasyutiko 8.18 6.30 2.02 4.08 0.38 979.37 80.43
2020 CNH / CNH Industrial N.V.
CNH Industrial is an equipment and services company. The company operates globally across three distinct segments: Agriculture, Construction and Financial Services. It develops, manufactures and sells specialized machines and services for the farming and construction industries, and supplies replacement parts and accessories. It also provides a full suite of financial services solutions. CNH Industrial has a network of facilities and dealerships that spans five continents, covering about 170 markets.
Makinarya at Kagamitan sa Konstruksyon 14,312.50 18.90 11.62 15.31 11.45 33.79 80.42
2023 ITRM / Iterum Therapeutics plc Mga Paghahanda sa Parmasyutiko 30.25 9.45 5.05 7.14 0.68 950.15 80.40
2026 CMMB / Chemomab Therapeutics Ltd. - Depositary Receipt (Common Stock)
Chemomab Therapeutics Ltd. is a biopharmaceutical firm based in Israel, primarily engaged in the discovery and development of innovative therapies for inflammatory and fibrotic diseases, which are often unmet medical needs. Their central focus is on the development of monoclonal antibodies, with a prominent project being CM-101, currently in phase 2 clinical trials. CM-101 targets the CCL24 chemokine and is explored for potential applications in diseases like primary sclerosing cholangitis, systemic sclerosis, and liver fibrosis. The company's therapeutic approach integrates targeting key regulators of chronic inflammation and fibrosis, aiming to halt disease progression and improve patient outcomes. Chemomab Therapeutics exemplifies a strategic focus within the niche of inflammatory and fibrotic medical conditions, employing advanced science to develop potentially groundbreaking treatments.
Mga Paghahanda sa Parmasyutiko 16.04 10.50 7.07 8.84 3.14 185.16 80.39
2029 GRAB / Grab Holdings Limited
Grab Holdings Limited, headquartered in Singapore, operates primarily in the technology sector, focusing on delivering a diverse range of services including ridesharing, food delivery, and financial services across Southeast Asia. Established originally as a taxi-hailing app in 2012, Grab has significantly expanded its offerings, positioning itself as a leading super app in the region. A key project for Grab is its financial services arm, which leverages its tech expertise to offer insurance and lending services, aiming to tap into the underbanked population in Southeast Asia. Furthermore, Grab continues to enhance its platform through strategic partnerships and technological advancements, such as its collaboration with autonomous vehicle companies and the integration of artificial intelligence to improve service delivery and operational efficiency.
Blangkong Check 20,380.00 8.40 5.30 6.21 4.99 24.27 80.38
2030 WING / Wingstop Inc. Mga Restaurant, Kainan, at Lugar ng Kainan 9,162.34 500.85 184.69 407.81 328.12 24.19 80.38
2031 NVNO / enVVeno Medical Corporation
EnVVeno Medical Corporation is headquartered in the United States and operates within the healthcare sector, specifically focusing on medical device manufacturing. The company specializes in developing and commercializing innovative technologies aimed at venous diseases, with a significant emphasis on minimally invasive solutions. A key project for EnVVeno Medical is their proprietary VenoValve® surgical implant, which is designed to address severe deep venous Chronic Venous Insufficiency (CVI). This implant represents a novel therapeutic avenue for patients suffering from this debilitating condition, and it is currently under clinical evaluation to assess its safety and efficacy. EnVVeno Medical's commitment to addressing unmet medical needs in venous diseases positions it as a notable entity in the medical device industry.
Mga Instrumento at Apparatus ng Surgical at Medikal 15.39 13.12 12.62 12.75 0.80 1,494.95 80.38
2032 LLY / Eli Lilly and Company
Eli Lilly and Company, headquartered in Indianapolis, Indiana, USA, operates as a global pharmaceutical leader primarily focused on the discovery, development, and marketing of pharmaceutical products. The company specializes in a broad range of therapeutic areas including diabetes, oncology, immunology, and neurology. Key projects of Eli Lilly involve the development of innovative treatments for complex diseases such as Alzheimer’s through their drug Donanemab, and diabetes with drugs like Mounjaro (tirzepatide). Additionally, their robust research and development efforts emphasize advancing a pipeline that addresses unmet medical needs, a strategy supported by substantial investments in both technology and strategic collaborations within the biotech and pharmaceutical sectors. This focus underscores Eli Lilly's commitment to innovation and its role in shaping the future of healthcare.
Mga Paghahanda sa Parmasyutiko 657,663.18 1,249.50 681.75 910.18 732.58 24.34 80.38
2034 SENS / Senseonics Holdings, Inc.
Senseonics Holdings, Inc., based in the United States, operates within the healthcare sector, specifically focusing on the development and commercialization of glucose monitoring systems for people with diabetes. A prominent player in medical technology, the company's main product, the Eversense® Continuous Glucose Monitoring (CGM) system, distinguishes itself with its long-term implantable device. This system allows for continual glucose monitoring for up to 90 and 180 days, offering significant advantages in terms of convenience and efficiency compared to traditional CGM systems. The innovative nature of Senseonics' solutions aligns with their commitment to enhancing diabetic care management through advanced sensor technology and data integration capabilities.
Mga Instrumentong Pang-industriya para sa Pagsukat, Pagpapakita, at Pagkontrol ng mga Variable ng Proseso; at Mga Kaugnay na Produkto 374.30 2.10 1.01 1.44 0.46 212.73 80.36
2036 SLP / Simulations Plus, Inc. Computer Integrated Systems Design 285.05 32.55 20.20 25.84 14.17 82.23 80.35
2038 PODC / PodcastOne, Inc. Computer Programming, Pagproseso ng Data, At Iba Pang Serbisyong Kaugnay ng Computer 41.32 5.25 3.79 4.46 1.58 184.24 80.34
2040 NRSN / NeuroSense Therapeutics Ltd. Mga Paghahanda sa Parmasyutiko 26.32 14.70 14.14 14.28 1.06 1,234.70 80.33
2043 LINC / Lincoln Educational Services Corporation Mga Serbisyong Pang-edukasyon 594.87 28.35 25.25 26.69 18.81 41.89 80.31
2044 SBAC / SBA Communications Corporation
SBA Communications Corporation is an American company based in Boca Raton, Florida, primarily operating in the telecommunications sector. The company is a leading independent owner and operator of wireless communications infrastructure, including towers, buildings, and rooftops. Its primary business comprises leasing antenna space on these structures to different telecommunications service providers under long-term contracts. SBA Communications also provides site development services, assisting wireless operators in developing their own network infrastructure. Key projects typically involve strategic acquisition and management of tower sites, enhancements in site leasing capacity, and expansion of international operations, particularly in markets such as South America. These activities enable SBA to support the rollout of next-generation network technologies, including 5G wireless systems, across its substantial portfolio of assets.
Mga Trust sa Pamumuhunan sa Real Estate 22,012.26 299.25 237.35 263.61 204.85 28.72 80.30
2045 XTIA / XTI Aerospace, Inc. 35.92 15.75 12.12 13.77 2.01 586.78 80.30
2047 TWLO / Twilio Inc.
Twilio Inc., based in the United States, is a prominent player in the Cloud Communications industry, providing a versatile platform for digital communication. The company offers a suite of services enabling businesses to improve customer engagement through channels such as SMS, email, voice, and video, leveraging a powerful Programmable Communications Cloud and a Super Network that connects to global telecommunications providers. Key projects include the development of AI-infused communication solutions and significant contributions to the expanding realm of Internet of Things (IoT) applications. Twilio continues to innovate with robust API offerings that empower developers to build and scale applications efficiently across diverse markets, maintaining its edge in a competitive sector.
Naka-prepack na Software 16,182.49 178.50 75.75 132.16 105.61 25.10 80.30
2048 FICO / Fair Isaac Corporation
Fair Isaac Corporation, commonly known as FICO, is a data analytics company based in the United States. It primarily operates in the financial services sector, providing a range of analytical, software, and data management products and services. FICO is renowned for its credit scoring system, which is widely used to assess consumer credit risk. The company’s key projects often revolve around the development and enhancement of algorithms and models for predictive analytics, decision management software, and fraud detection capabilities. FICO serves a global clientele, which includes financial institutions, insurers, healthcare organizations, and government agencies, helping them make informed, efficient, and effective decisions in real-time business environments.
Mga Serbisyo sa Negosyo, Hindi Nauuri sa Ibang Lugar 36,524.92 2,415.00 1,242.30 1,932.03 1,521.64 26.84 80.29
2051 FBIO / Fortress Biotech, Inc.
Fortress Biotech, Inc., based in the United States, operates predominantly within the biopharmaceutical sector, focusing on the development and commercialization of novel pharmaceutical therapies. The company's business model hinges on developing partnerships with the biotechnology industry, leveraging their expertise to establish and support a diverse portfolio of project subsidiaries. Key projects typically involve the innovation of treatment options for rare diseases and hard-to-treat conditions, highlighting Fortress Biotech's commitment to addressing unmet medical needs. Their strategic approach integrates in-licensing, developing, and potentially commercializing cutting-edge therapeutic products, often navigating through the complex regulatory landscapes that characterize the pharmaceutical industry.
Mga Paghahanda sa Parmasyutiko 76.76 27.30 4.04 15.64 2.58 508.56 80.28
2052 MU / Micron Technology, Inc.
Micron Technology, Inc., based in the United States, is a prominent player in the semiconductor sector. The company specializes in the design and manufacturing of memory and storage solutions, which are crucial components in advanced computing hardware. Its product lineup includes dynamic random-access memory (DRAM), NAND flash memory, and NOR flash memory, addressing the needs of a diverse range of markets such as computing, networking, and mobile. Key projects by Micron often focus on the development of innovative memory technologies that enhance performance and data security, with significant advancements in 3D XPoint non-volatile memory technology. Micron’s efforts in pushing the boundaries of memory and storage technology underline its strategic role in the global semiconductor industry.
Mga Semiconductor at Mga Kaugnay na Device 133,053.18 210.00 86.86 147.04 119.01 23.53 80.27
2053 HURA / TuHURA Biosciences, Inc. 134.52 15.75 9.09 11.54 2.70 328.15 80.27
2054 PLMR / Palomar Holdings, Inc.
Palomar Holdings, Inc., based in the United States, operates primarily within the specialty property insurance industry. The company focuses on markets that are underserved by traditional insurance providers, with an emphasis on addressing complex risks. Its portfolio includes residential and commercial earthquake insurance, specialty homeowners insurance, and other unique products like flood, wind, and commercial all-risk insurance. Palomar's strategy capitalizes on leveraging cutting-edge analytics and underwriting expertise to offer innovative insurance solutions. Notably, the firm is recognized for its use of proprietary analytics that enhance its risk assessment capabilities, allowing it to effectively navigate and price niche insurance segments. Integral to its mission, Palomar continually seeks to broaden its product offerings and geographic footprint, reinforcing its presence in the specialty insurance sector.
Fire, Marine, at Casualty Insurance 3,294.13 183.75 152.51 170.14 123.02 38.31 80.26
2057 LOAR / Loar Holdings Inc. 6,620.04 112.12 90.90 99.14 70.66 40.20 80.25
2059 WST / West Pharmaceutical Services, Inc.
West Pharmaceutical Services, Inc. is a U.S.-based global leader in the healthcare industry, specializing in the production of technologically advanced, high-quality integrated containment and delivery systems for injectable drugs and healthcare products. The company focuses on developing and manufacturing packaging components and delivery systems that enhance the administration of pharmaceuticals, improving drug efficacy and patient compliance. Key projects typically involve innovative solutions like the development of self-injection technologies and advanced drug container systems designed to protect sensitive molecules and extend product shelf life. West Pharmaceutical's commitment to innovation is evident in its strategic emphasis on expanding its capabilities in biologics, where it continually seeks to meet the complex demands of new-generation biopharmaceuticals. The company operates globally, leveraging state-of-the-art technology and regulatory expertise to serve the pharmaceutical, biotechnology, and generic drug industries.
Mga Instrumento at Apparatus ng Surgical at Medikal 17,755.71 367.50 262.60 320.57 246.95 29.77 80.25
2063 AKAM / Akamai Technologies, Inc.
Akamai Technologies, Inc., based in the United States, operates primarily within the technology sector, focusing on providing cloud services and security solutions. As a leader in content delivery network (CDN) services, Akamai ensures secure, fast delivery of media and software, and enhances cloud security for businesses globally. Key projects and services include edge security, web and mobile performance solutions, and internet optimization. These offerings are essential for industries requiring reliable and secure internet operations, particularly as digital landscapes evolve. Akamai's strategic emphasis on cybersecurity and performance optimization reflects its commitment to advancing internet reliability and safety, meeting the expanding needs of modern enterprises and networks around-the-clock.
Mga Serbisyo sa Negosyo, Hindi Nauuri sa Ibang Lugar 11,318.45 147.00 66.66 100.74 79.13 27.27 80.23
2064 KNSA / Kiniksa Pharmaceuticals, Ltd. Mga Paghahanda sa Parmasyutiko 2,479.34 56.70 38.38 45.70 33.49 36.28 80.23
2068 STVN / Stevanato Group S.p.A.
Stevanato Group S.p.A., based in Italy, operates primarily in the pharmaceutical packaging and drug delivery systems sector. Founded in 1949, the company specializes in the production of glass vials, syringes, and other containers essential for the storage and administration of pharmaceuticals. Stevanato Group is notable for its integration of advanced technologies, including high-precision glass molding and visual inspection systems, to ensure product quality and integrity. A key project illustrating its innovative approach is the development of its SG EZ-fill® platform, which provides sterile, ready-to-fill syringes and vials, significantly streamlining the pharmaceutical manufacturing process. This initiative reflects the company's commitment to enhancing operational efficiencies and supporting the safety of drug therapies.
Mga Instrumento at Apparatus ng Surgical at Medikal 6,281.39 38.85 23.23 29.69 23.01 29.29 80.22
2074 EKSO / Ekso Bionics Holdings, Inc. Pangkalahatang Makinarya at Kagamitang Pang-industriya, Wala sa Ibang Lugar 9.79 63.00 9.60 35.44 3.75 842.69 80.21
2078 PRTH / Priority Technology Holdings, Inc. Mga Serbisyo sa Negosyo, Hindi Nauuri sa Ibang Lugar 668.74 16.80 10.10 12.85 8.37 53.00 80.20
2081 CLDI / Calidi Biotherapeutics, Inc. 1.13 10.50 10.10 10.20 1.65 520.63 80.18
2086 CMCO / Columbus McKinnon Corporation
Columbus McKinnon Corporation, headquartered in the United States, specializes in the design, manufacturing, and marketing of material handling products and systems. Operating primarily in the industrial sector, the company focuses on delivering comprehensive lifting and motion control solutions that enhance efficiency and worker safety. Its diverse product range includes hoists, cranes, actuators, and rigging tools, servicing various industries from construction to energy. Key projects often emphasize innovation in automation and productivity, integrating Internet of Things (IoT) technology to advance the functionality and intelligence of its systems. Columbus McKinnon's commitment to technological advancement and global market expansion solidifies its position as a leader in the material handling equipment industry.
Makinarya at Kagamitan sa Konstruksyon 425.07 37.80 15.15 28.56 14.98 90.59 80.17
2090 CEVA / CEVA, Inc.
CEVA, Inc., based in the United States, is a prominent player in the semiconductor industry, specializing in signal processing IP for the smarter, connected world. The company develops intellectual property for digital signal processors (DSP), artificial intelligence processors, wireless platforms, and complementary software for sensor processing, image enhancement, computer vision, voice input, and artificial intelligence. CEVA's technology is vital for the creation of mobile, consumer, automotive, industrial, and IoT products. Key projects focus on developing advanced DSP architectures and platforms for 5G, powering a wide array of devices from smartphones to vehicles, thus playing a crucial role in modern communications and computing applications. The company's innovative solutions support a network of system integrators and chip manufacturers, enhancing the capabilities and performance of their respective products.
Computer Programming, Pagproseso ng Data, At Iba Pang Serbisyong Kaugnay ng Computer 529.17 42.00 21.21 32.47 22.22 46.33 80.16
2094 ICHR / Ichor Holdings, Ltd.
Ichor Holdings, Ltd., based in the United States, operates prominently within the semiconductor industry. The company specializes in the design, engineering, and manufacturing of critical fluid delivery subsystems for semiconductor capital equipment. Ichor's offerings primarily support the deposition and etch processes used in the fabrication of integrated circuits in devices such as computers, mobile devices, and others. A key aspect of its business strategy includes the pursuit of technology innovations and operational excellence that enhance the performance and cost-effectiveness of semiconductor manufacturing equipment. Alongside its core product offerings, Ichor actively engages in strategic partnerships and acquisitions to expand its market reach and technological capabilities, thereby reinforcing its position in the competitive semiconductor sector.
Mga Semiconductor at Mga Kaugnay na Device 577.34 36.75 18.18 24.65 16.85 46.20 80.14
2096 CERO / CERo Therapeutics Holdings, Inc. 9.15 63.00 30.30 45.90 7.52 499.61 80.14
2097 RPAY / Repay Holdings Corporation Mga Serbisyo sa Negosyo, Hindi Nauuri sa Ibang Lugar 473.88 12.60 5.05 8.35 5.92 40.95 80.13
2100 ENLV / Enlivex Therapeutics Ltd.
Enlivex Therapeutics Ltd. is a biotechnology company based in Israel, primarily engaged in the research and development of drug products within the biopharmaceutical sector. The company is known for its involvement in developing innovative therapies aimed at modulating the immune system to treat conditions characterized by hyper-immune responses, such as sepsis and solid tumors. A key project developed by Enlivex is Allocetra™, an innovative therapy designed for conditions involving dysfunctional immune responses, which has shown promising results in clinical studies for overcoming severe sepsis and COVID-19 complications. This innovative approach positions Enlivex Therapeutics at the forefront of addressing critical care conditions by restoring immune balance and preventing organ failure.
Mga Paghahanda sa Parmasyutiko 25.04 13.65 7.07 10.20 1.05 871.43 80.12
2102 BFRI / Biofrontera Inc.
Biofrontera Inc. is a biopharmaceutical company based in the United States, primarily engaged in the development and commercialization of dermatological products and therapies. Its core focus is on the treatment and management of skin conditions, primarily actinic keratosis, a type of precancerous skin lesion caused by sun exposure. A key product of Biofrontera is Ameluz®, a prescription medication used in combination with the company’s photodynamic therapy lamp, BF-RhodoLED®, for treating mild and moderate actinic keratosis on the face and scalp. The company is involved in continuous research to expand the indications for its products and improve therapeutic outcomes in dermatological care, positioning itself as a leader in photodynamic therapy innovations.
Mga Paghahanda sa Parmasyutiko 8.97 10.50 3.03 6.63 0.89 649.49 80.11
2107 SAIL / SailPoint, Inc. Naka-prepack na Software 11,487.81 31.50 16.16 26.67 20.64 29.09 80.08
2109 UGRO / urban-gro, Inc. Machinery, Equipment, And Supplies 3.15 3.03 3.06 0.41 639.49 80.06
2110 COHR / Coherent Corp.
Coherent Corp., headquartered in the United States, is a prominent player in the photonics and lasers industry, providing a broad range of laser-based technologies, components, and systems. Its expertise spans areas such as microelectronics, scientific research, and OEM components, contributing crucially to advancements and manufacturing processes in sectors like electronics, automotive, and healthcare. One significant aspect of Coherent Corp.'s project portfolio includes the development and enhancement of laser technologies for material processing applications, aiding in precision manufacturing tasks. Additionally, their investments in R&D ensure continuous innovation in durable and efficient laser solutions, aligning with the ever-evolving demands of their global client base.
Mga Instrumentong Analitikal sa Laboratory 14,068.08 138.60 85.85 112.62 90.47 24.40 80.05
2113 NOMD / Nomad Foods Limited
Nomad Foods Limited is a company based in the United Kingdom and operates predominantly within the frozen foods industry. Renowned for its focus on sustainable and convenient food products, the company has a diverse portfolio that includes leading European brands such as Birds Eye, Findus, and Iglo. Nomad Foods is actively engaged in key projects aimed at product innovation and sustainability, which includes efforts to improve the nutritional profile of its products while minimizing environmental impact. Additionally, the company has been involved in strategic acquisitions to expand its market presence across Europe. Through these initiatives, Nomad Foods aims to solidify its position as a leader in the frozen foods market while addressing the evolving preferences and needs of consumers.
Pagkain At Mga Kamag-anak na Produkto 2,334.66 28.35 18.18 21.42 15.54 37.84 80.04
2116 NCNA / NuCana plc - Depositary Receipt (Common Stock)
NuCana plc is a biopharmaceutical company based in the United Kingdom, primarily engaged in developing novel treatments for patients with significant unmet medical needs in the oncology sector. The company utilizes its proprietary ProTide technology to transform nucleoside analogs into more effective and safer therapies, actively seeking to improve the outcomes of cancer patients. Key projects include their leading drug candidates, NUC-1031 (Acelarin), being evaluated for use in biliary tract cancer, and NUC-3373, targeted for colorectal cancer treatment. As NuCana continues to advance its clinical trials, it remains committed to leveraging its technology in developing therapies that offer new options for treatment-resistant cancers, emphasizing a science-driven approach to medicine development.
Mga Paghahanda sa Parmasyutiko 6.09 3.19 699.37 80.03
2121 WATT / Energous Corporation Kagamitan sa Pag-broadcast sa Radyo at Telebisyon at Komunikasyon 8.80 63.00 60.60 61.20 7.46 725.91 80.01
2126 LTRN / Lantern Pharma Inc. Mga Paghahanda sa Parmasyutiko 43.93 26.25 15.15 20.40 4.08 400.86 80.00
2127 EDSA / Edesa Biotech, Inc. Mga Paghahanda sa Parmasyutiko 16.29 17.85 5.05 10.54 2.34 354.31 79.99
2129 KSPI / Joint Stock Company Kaspi.kz - Depositary Receipt (Common Stock)
Joint Stock Company Kaspi.kz, based in Kazakhstan, operates primarily in the technology and financial services industries. The company is extensively engaged in developing and promoting a unified online platform that facilitates a range of services, including consumer banking, payments, and e-commerce. Kaspi.kz has shown significant growth by leveraging its mobile app to dominate various segments of the market such as digital wallets and online retail. A notable project of Kaspi.kz is its marketplace, which integrates e-commerce with financial services for improved consumer service. The company also actively invests in technology to enhance user experience and increase the efficiency of its financial services. Through these strategic initiatives, Kaspi.kz aims to sustain its market leadership and drive further digital transformation in the region.
17,905.13 156.45 111.10 126.92 93.96 35.08 79.98
2132 AMT / American Tower Corporation
Mobilezone Holding AG is a Swiss-based company primarily engaged in the telecommunications sector. Its business operations are divided into two segments: Trade and Service Providing. Mobilezone offers a comprehensive portfolio of mobile and fixed network telephony, digital TV, and internet, along with a wide range of devices and accessories.
Mga Trust sa Pamumuhunan sa Real Estate 95,453.01 295.05 219.17 254.26 203.85 24.78 79.96
2135 OLED / Universal Display Corporation
Universal Display Corporation, based in the United States, is a prominent player in the technology sector, primarily focusing on the development and commercialization of organic light-emitting diode (OLED) technologies and materials. As a leader in OLED innovation, the company licenses its state-of-the-art technology to manufacturers of display and lighting products worldwide. Their key contributions include producing and selling OLED materials used in televisions, smartphones, tablets, and lighting systems. Universal Display Corporation also engages in research and development to further enhance the capabilities and applications of OLED technology, aiming to broaden its adoption across various sectors and continue its growth trajectory in the evolving digital display market.
Electronic Components And Accessories 6,587.75 231.00 161.60 184.26 138.59 32.95 79.95
2137 CXT / Crane NXT, Co.
Crane Company, based in Stamford, Connecticut, USA, operates primarily in the diversified industrials sector, with significant activities across fluid handling, engineered materials, and aerospace electronics. The company specializes in manufacturing industrial products, including valves, pumps, and brake systems, which cater to a wide array of markets such as chemical, oil & gas, and aerospace. Key projects often involve advanced fluid handling systems and components that are essential for infrastructure and energy applications, showcasing Crane's emphasis on reliability and innovation in demanding environments. Through strategic acquisitions and a focus on technology-driven engineering, Crane Company continues to expand its footprint and enhance its product offerings, thereby reinforcing its position in the global industrial marketplace.
Miscellaneous Fabricated Metal Products 3,427.75 198.45 57.57 91.95 59.73 53.94 79.94
2138 AKTX / Akari Therapeutics, Plc - Depositary Receipt (Common Stock)
Akari Therapeutics, Plc, based in the United Kingdom, is a biopharmaceutical company primarily engaged in developing and commercializing therapies to treat rare and orphan autoimmune and inflammatory diseases caused by excessive activation of complement component C5. Among its notable projects, Akari focuses on developing its lead drug candidate, Nomacopan (formerly Coversin), a complement inhibitor that addresses critical mediators of inflammation in diseases such as paroxysmal nocturnal hemoglobinuria (PNH), atypical Hemolytic Uremic Syndrome (aHUS), and severe asthma. The innovative therapies in its pipeline target underserved conditions and leverage the company's expertise in modulation of the immune system, demonstrating a strategic approach to addressing some of the complexities of autoimmune diseases.
Mga Paghahanda sa Parmasyutiko 24.79 7.35 5.05 6.12 0.76 705.26 79.94
2141 XTNT / Xtant Medical Holdings, Inc. Mga Instrumento at Apparatus ng Surgical at Medikal 89.02 2.10 1.52 1.78 0.64 180.84 79.92
2145 IFF / International Flavors & Fragrances Inc.
International Flavors & Fragrances Inc. is a United States-based company primarily engaged in the creation and manufacturing of flavors and fragrances used in a wide array of consumer products. The core industry sectors it serves include food and beverages, perfumes, and personal care and household products. The company plays a vital role in developing sensory experiences through its extensive portfolio of aromatic and taste compounds. Key projects often focus on sustainable and innovative practices, involving bio-based ingredients and green chemistry principles, reflecting the company’s commitment to environmental sustainability and technological advancement in the flavors and fragrances sector. International Flavors & Fragrances Inc. strives to blend unique sensory talents with cutting-edge science to concoct distinctive and appealing products.
Industrial Organic Chemicals 17,302.81 115.62 68.68 85.97 67.51 27.35 79.89
2146 KSCP / Knightscope, Inc. Communications Equipment, Not Elsewhere Classified 44.90 27.30 8.08 15.64 6.04 158.91 79.89
2147 SNOA / Sonoma Pharmaceuticals, Inc.
Sonoma Pharmaceuticals, Inc., based in the United States, is a distinguished entity within the healthcare sector, focusing primarily on the development and production of stabilized hypochlorous acid (HOCl) products for a variety of applications. These applications span across wound care, eye care, nasal care, oral care, and dermatological conditions. The company harnesses its proprietary Microcyn® technology to produce products that assist in managing conditions such as atopic dermatitis, scar management, and surgical issues. Sonoma Pharmaceuticals prides itself on delivering innovative, safe, and effective solutions to improve clinical outcomes and reduce healthcare costs, showing a commitment to advancing technology while promoting healing solutions on a global scale.
Mga Instrumento at Apparatus ng Surgical at Medikal 7.31 15.54 14.95 15.10 4.45 240.77 79.88
2150 NUTX / Nutex Health Inc. Mga Serbisyo sa Negosyo, Hindi Nauuri sa Ibang Lugar 464.11 315.00 222.20 253.30 83.79 201.73 79.87
2154 LEXX / Lexaria Bioscience Corp. Mga Paghahanda sa Parmasyutiko 17.22 8.40 4.04 6.12 0.88 595.22 79.86
2156 INBS / Intelligent Bio Solutions Inc.
Intelligent Bio Solutions Inc., based in the United States, operates in the healthcare and biotechnology industry, primarily focusing on developing advanced diagnostic devices. The company endeavors to enhance patient outcomes through the innovation of rapid and reliable diagnostic solutions that cater to a range of medical conditions and public health concerns. Key projects involve the development of point-of-care products intended to deliver immediate diagnostics for critical health parameters, thus facilitating timely medical responses. Intelligent Bio Solutions Inc.'s initiative includes integrating these technologies within both institutional and home care settings, emphasizing the provision of essential health data that supports clinical decisions and improves patient management across various medical environments.
Mga Instrumento at Apparatus ng Surgical at Medikal 11.94 1.62 650.92 79.85
2158 ICLR / ICON Public Limited Company
ICON Public Limited Company, based in Ireland, operates predominantly within the global healthcare sector, specializing in providing clinical research services to the pharmaceutical, biotechnology, and medical device industries. As a contract research organization (CRO), ICON supports the development, analysis, and commercialization of new medicines with a comprehensive range of services from laboratory to consulting services. Key projects typically involve managing large-scale clinical trials, data management, and regulatory support aimed at advancing medical innovations from conception through to market approval. This strategic positioning highlights ICON’s critical role in accelerating healthcare solutions and enhancing patient care worldwide, marking it as an essential facilitator in the progression of medical sciences.
Komersyal na Pisikal at Biyolohikal na Pananaliksik 13,840.33 252.00 181.80 222.97 177.94 25.29 79.84
2159 XPER / Xperi Inc. Naka-prepack na Software 275.08 13.65 9.09 11.22 6.00 86.84 79.83
2162 UPB / Upstream Bio, Inc. 919.41 78.75 75.75 76.50 17.13 347.63 79.82
2165 SHIP / Seanergy Maritime Holdings Corp.
Seanergy Maritime Holdings Corp., headquartered in Greece, operates primarily in the dry bulk shipping sector, focusing on the transportation of dry bulk goods such as iron ore, coal, and grains across global shipping routes. As an international shipping company, Seanergy strategically utilizes its fleet of Capesize vessels, which are among the larger cargo ships specialized for traversing major canal routes such as Panama and Suez. The company engages in key projects aimed at fleet expansion and modernization, ensuring energy efficiency and compliance with international maritime regulations. By focusing on operational efficiency and market adaptability, Seanergy aims to solidify its position within the competitive dry bulk shipping industry, enhancing value for stakeholders and responding dynamically to market demands.
Deep Sea Dayuhang Transportasyon ng Freight 158.98 15.75 9.09 11.98 7.79 53.46 79.81
2170 ADAG / Adagene Inc. - Depositary Receipt (Common Stock) Mga Paghahanda sa Parmasyutiko 100.39 22.12 3.54 9.84 2.14 361.75 79.78
2174 MH / McGraw Hill, Inc. 2,419.20 30.03 15.15 21.38 14.52 47.24 79.78
2176 JAGX / Jaguar Health, Inc.
Jaguar Health is a commercial stage pharmaceuticals company focused on developing novel, plant-based, non-opioid, and sustainably derived prescription medicines for people and animals with GI distress, specifically chronic, debilitating diarrhea.
Mga Paghahanda sa Parmasyutiko 2.49 16.80 16.16 16.32 1.63 913.66 79.77
2181 LBRDA / Liberty Broadband Corporation
Liberty Broadband Corporation is an American company primarily engaged in the communications industry. Based in the United States, it functions as a holding company with significant interests in Charter Communications as well as a subsidiary, Skyhook, which specializes in location technology services. A core aspect of its business involves the management of its investment portfolio to optimize shareholder value and ensure sustained growth. The company’s strategic focus is heavily oriented towards maximizing its influence and operational capabilities within the broadband communications sector. Key projects typically include leveraging technological advancements to enhance broadband capabilities and exploring synergistic opportunities that align with its broad investment philosophy in the telecommunications spectrum.
Cable at Iba pang Pay Television Services 1,127.35 136.32 83.83 107.82 60.67 77.78 79.74
2184 EDIT / Editas Medicine, Inc.
Editas Medicine, Inc., based in the United States, operates within the biotechnology sector and is notable for its pioneering efforts in gene editing technology. Specializing in the CRISPR/Cas9 and CRISPR/Cas12 systems, the company focuses on developing transformative gene-editing therapies to treat a diverse range of diseases with unmet medical needs. Key projects include a leading development program targeting Leber Congenital Amaurosis type 10 (LCA10), a severe genetic eye disorder, endeavoring to correct this mutation-driven ailment at the DNA level. Additionally, Editas Medicine sustains active research in exploring treatment options for other genetic conditions, including sickle cell disease and beta-thalassemia, signifying its strategic commitment to medical innovation and genetic disease treatment.
Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 224.15 6.30 1.01 3.97 2.57 54.65 79.73
2187 AVDL / Avadel Pharmaceuticals plc
Avadel Pharmaceuticals plc is an Ireland-based biopharmaceutical company, primarily engaged in the development and commercialization of proprietary pharmaceutical products. The company specializes in hospital and other therapeutic products within the United States. One of its key projects involves the development of FT218, an investigational, once-nightly formulation of sodium oxybate for the treatment of narcolepsy, which is currently under review by the U.S. Food and Drug Administration (FDA). Avadel’s strategy focuses on leveraging its proprietary drug delivery technologies to provide novel formulations that aim to improve patient outcomes and enhance the overall patient experience, addressing both existing and unmet medical needs within the pharmaceutical sector.
Mga Paghahanda sa Parmasyutiko 1,427.94 25.20 16.16 19.51 14.76 32.21 79.72
2194 MSAI / MultiSensor AI Holdings, Inc. Optical Instruments and Lenses 23.08 2.62 2.52 2.55 0.67 276.44 79.69
2196 STNG / Scorpio Tankers Inc.
Scorpio Tankers is a provider of marine transportation of petroleum products worldwide. The Company currently owns or finance leases 109 product tankers (38 LR2 tankers, 12 LR1 tankers, 45 MR tankers and 14 Handymax tankers) with an average age of 3.3 years and time or bareboat charters‐in 13 product tankers (one LR2 tanker, five MR tankers and seven Handymax tankers).
Deep Sea Dayuhang Transportasyon ng Freight 2,380.01 78.75 49.49 63.92 50.40 26.83 79.67
2198 BARK / BARK, Inc. Mga Tindahan, Hindi Nauuri sa Ibang Lugar 153.24 3.15 2.02 2.38 0.90 162.05 79.66
2199 CVGI / Commercial Vehicle Group, Inc.
Commercial Vehicle Group, Inc. (CVG), based in the United States, operates predominantly in the automotive and commercial vehicle industries. The company specializes in manufacturing and supplying various products, including electrical systems, seating systems, cabin structures, controls, and other related components. CVG caters primarily to the global commercial vehicle market, serving notable heavy-duty trucks and construction equipment sectors. Key projects and initiatives typically emphasize innovation in vehicle solutions, focusing on improving driver comfort, vehicle performance, and overall safety. The company is actively involved in designing and engineering enhancements for a range of commercial applications, demonstrating a strong commitment to meeting the evolving needs of a global clientele in the commercial vehicle sphere.
Mga Bahagi at Accessory ng Sasakyan ng Motor 55.65 4.20 4.04 4.08 1.76 129.21 79.66
2202 ATEX / Anterix Inc.
Anterix Inc., based in the United States, operates primarily within the telecommunications industry, focusing on facilitating the modernization of critical infrastructure by delivering broadband connectivity. The company specifically catifies itself in developing and leasing spectrum, primarily in the 900 MHz band, tailored to support secure, private broadband networks for utility companies and other critical infrastructure providers. Key projects include collaborations with major utility companies to deploy private LTE networks, enhancing communication resilience and operational efficiency across power grids and other essential services. Through its dedicated services, Anterix plays a pivotal role in the integration of robust telecommunications frameworks essential for contemporary digital utility management and smart grid applications.
Komunikasyon sa Telepono, Maliban sa Radiotelephone 445.15 75.60 44.44 59.16 23.74 148.47 79.65
2205 MARA / MARA Holdings, Inc. Mga Serbisyo sa Pananalapi 5,795.59 29.40 13.13 21.79 15.98 36.24 79.64
2210 AVPT / AvePoint, Inc. Naka-prepack na Software 3,453.18 27.30 18.18 21.93 16.36 34.09 79.63
2222 WH / Wyndham Hotels & Resorts, Inc. Mga Hotel at Motel 6,668.97 123.90 95.95 107.46 86.61 24.10 79.60
2233 PAL / Proficient Auto Logistics, Inc. 219.00 13.65 12.12 12.92 7.90 63.65 79.56
2243 FLGC / Flora Growth Corp. Mga Paghahanda sa Parmasyutiko 11.83 163.80 30.30 94.86 20.46 363.86 79.51
2244 AMAT / Applied Materials, Inc.
Applied Materials, Inc. is a leading corporation based in the United States, primarily engaged in the provision of equipment, services, and software for the semiconductor industry. The company plays a pivotal role in the fabrication of semiconductor chips, offering tools necessary for wafer processing and semiconductor manufacturing. Its technology solutions are integral to advancing microelectronics, with applications ranging from innovative displays to photovoltaic products. Applied Materials is at the forefront of the materials engineering space, actively driving transformative innovations across various sectors, including electronics and energy conservation. Through its comprehensive portfolio and continuous investment in R&D, Applied Materials sustains its leadership by addressing both current and future market demands in an ever-evolving technological landscape.
Mga Semiconductor at Mga Kaugnay na Device 128,286.48 252.00 151.50 197.33 160.76 22.69 79.51
2246 GETY / Getty Images Holdings, Inc.
Getty Images, Inc. is a US-based company that primarily operates as a supplier of stock images, editorial photography, video, and music for businesses and consumers. Their content offerings range from contemporary creative imagery to news, sports, entertainment, and archival content.
Mga Serbisyo sa Negosyo, Hindi Nauuri sa Ibang Lugar 763.25 7.35 1.87 4.20 1.84 128.83 79.51
2247 ICCM / IceCure Medical Ltd Mga Instrumento at Apparatus ng Surgical at Medikal 65.45 3.15 2.02 2.64 1.12 136.93 79.51
2248 GDEN / Golden Entertainment, Inc.
Golden Entertainment, Inc., headquartered in the United States, operates as a diversified gaming company. Active primarily within the gaming and hospitality industry, Golden Entertainment owns and manages casino properties, resorts, and distributed gaming operations across various states including Nevada and Maryland. Among its significant assets, the company counts the Strat Hotel, Casino, and SkyPod in Las Vegas, alongside other regional casinos and over 10,000 gaming devices stationed in Nevada and Montana. Its portfolio extends to dining and entertainment venues within its properties. The company's strategic operations focus on leveraging its broad spectrum of assets to generate robust revenue streams while enhancing customer experiences in its markets. This integration is aimed at driving sustainable growth within the competitive landscape of the gaming industry.
Sari-saring Libangan At Libangan 653.66 40.95 29.29 34.55 24.87 39.10 79.51
2250 TNON / Tenon Medical, Inc. Mga Instrumento at Apparatus ng Surgical at Medikal 9.79 12.60 2.78 6.04 1.24 384.74 79.50
2255 ALTO / Alto Ingredients, Inc.
Alto Ingredients, Inc., based in the United States, operates primarily in the specialty chemical industry, focusing on the production and distribution of high-quality alcohol products and essential ingredients. The company specializes in manufacturing specialty alcohols and essential ingredients used in various consumer goods including foods, beverages, and health care products. A key aspect of its business includes leveraging technology and innovation in fermentation and distillation processes to ensure product purity and performance. Alto Ingredients is also actively engaged in developing and marketing renewable fuels, which aligns with global sustainability efforts. Through strategic partnerships and ongoing research and development, the company aims to expand its market reach and enhance its portfolio of specialty products.
Industrial Organic Chemicals 86.54 5.78 2.52 4.08 1.13 263.96 79.46
2256 SGHC / Super Group (SGHC) Limited Sari-saring Libangan At Libangan 5,861.52 17.85 14.14 15.59 11.63 33.95 79.46
2257 WBD / Warner Bros. Discovery, Inc.
Warner Bros. Discovery, Inc., based in the United States, operates as a global entertainment conglomerate, primarily engaging in the media and entertainment industry. The company resulted from the merger between WarnerMedia and Discovery, Inc., combining vast portfolios of content across television, film, and streaming platforms. Key projects include managing a broad array of networks such as CNN, HBO, and Discovery Channel, alongside a significant presence in streaming services through platforms like HBO Max. Warner Bros. Discovery, Inc. focuses on delivering diverse and rich content, spanning numerous genres and formats to capture a wide audience worldwide, and continuously adapts to the evolving landscape of digital media and entertainment consumption.
Komunikasyon sa Telepono, Maliban sa Radiotelephone 28,784.25 25.20 8.08 14.64 11.64 25.86 79.45
2263 CXDO / Crexendo, Inc. Komunikasyon sa Telepono, Maliban sa Radiotelephone 190.01 11.55 7.58 8.74 6.32 38.78 79.41
2265 MNOV / MediciNova, Inc. Mga Paghahanda sa Parmasyutiko 64.74 9.45 5.05 7.14 1.31 440.91 79.41
2270 OWLT / Owlet, Inc. Pagsukat at Pagkontrol ng Mga Device, Hindi Nauuri sa Ibang Lugar 122.58 15.75 11.11 13.46 7.53 79.04 79.39
2271 PHUN / Phunware, Inc.
Phunware, Inc., based in the United States, operates within the software and technology sector, specializing in fully integrated enterprise cloud platforms for mobile. The company is prominent for its Multiscreen-as-a-Service (MaaS) platform which provides comprehensive products and solutions for mobile marketing, analytics, and monetization. The platform enables brands to engage, manage, and monetize their mobile applications. Phunware's strategic projects include innovative mobile solutions for high-profile clients in healthcare, retail, and entertainment sectors, leveraging their capabilities in location-based services, content management, and analytics to deliver tailored, scalable solutions aimed at enhancing user engagement and operational efficiency. These offerings underscore Phunware's commitment to harnessing mobile technology's transformational impact across diverse industry verticals.
Mga Serbisyo sa Pagproseso ng Computer at Paghahanda at Pagproseso ng Data 52.05 13.12 3.03 6.12 2.58 137.49 79.39
2279 COCP / Cocrystal Pharma, Inc.
Cocrystal Pharma, Inc., based in the United States, operates in the biotechnology sector with a focus on discovering and developing novel antiviral therapeutics. The company leverages proprietary technology to design unique treatments targeting viral replication enzymes, addressing diseases such as influenza, coronavirus, and norovirus. As of 2023, Cocrystal Pharma has been actively developing broad-spectrum antiviral drugs, including candidates for COVID-19 and influenza. Key projects include the preclinical development of CC-42344, a potent influenza A polymerase inhibitor, and ongoing work on inhibitors targeting the replication machinery of coronaviruses, underscoring its commitment to addressing global antiviral drug resistance challenges through innovative pharmaceutical developments.
Mga Paghahanda sa Parmasyutiko 15.26 8.40 6.06 7.14 1.50 376.00 79.37
2280 BRTX / BioRestorative Therapies, Inc.
BioRestorative Therapies, Inc. is a life sciences company based in the United States, primarily engaged in the development of regenerative medicine therapies that target various medical conditions. One of its key projects is the development of a biological disc to alleviate herniated lumbar disc pain, an innovation in non-surgical treatment. Additionally, the company is actively involved in a brown fat program directed towards metabolic disorders, such as diabetes and obesity. This aligns with their overall strategy to lead in the field of regenerative medicine by focusing on cell-based therapies designed to address conditions where current treatment options are limited or inadequate, thus highlighting their commitment to advancing medical science through innovation.
Sari-saring Serbisyong Pangkalusugan At Kaalyadong, Hindi 14.74 8.40 8.08 8.16 1.84 341.70 79.37
2285 KORE / KORE Group Holdings, Inc. Mga Serbisyo sa Komunikasyon, Hindi Nauuri sa Ibang Lugar 41.41 9.45 3.03 6.12 2.40 147.92 79.35
2286 AD / Array Digital Infrastructure, Inc. Komunikasyon sa Radiotelephone 4,629.38 88.20 59.91 76.61 53.83 42.32 79.34
2289 ECX / ECARX Holdings Inc. Computer Integrated Systems Design 557.09 5.25 2.68 3.87 1.62 137.29 79.33
2290 COIN / Coinbase Global, Inc.
Coinbase Global, Inc. is a prominent financial platform based in the United States, primarily engaged in the business of digital currency exchange. Founded in 2012, the company has become a key player within the fintech and cryptocurrency industries by offering a secure online platform for buying, selling, transferring, and storing digital currency. Coinbase aims to increase economic freedom in the world by making cryptocurrencies accessible globally, alongside providing related services like custody, asset management, and staking. Key projects include the integration of blockchain technology to enhance security and transparency, and expanding their crypto services to include more educational tools, APIs for developers, and institutional-grade solutions for larger clients.
Mga Serbisyo sa Pananalapi 78,130.01 535.50 174.04 377.46 304.54 23.89 79.33
2292 LUCK / Lucky Strike Entertainment Corporation Mga Serbisyo sa Libangan at Libangan 1,500.18 18.90 9.09 13.88 10.70 29.63 79.31
2293 LVO / LiveOne, Inc. Mga Restaurant, Kainan, at Lugar ng Kainan 54.74 4.20 1.21 2.33 0.55 322.68 79.30
2298 MTLS / Materialise NV - Depositary Receipt (Common Stock)
Materialise NV, headquartered in Belgium, operates within the additive manufacturing industry, often known as 3D printing. The company is involved in creating software solutions, complex 3D printing services, and the fabrication of customized medical products like orthopedic and dental implants. A notable aspect of Materialise NV is its commitment to innovation in the healthcare sector, specifically through its patient-specific medical and dental solutions. In addition to healthcare, the company actively serves a variety of industries including aerospace, automotive, and consumer products, through both the production of end parts and the development of advanced 3D printing software. This approach highlights Materialise's strategic focus on leveraging cutting-edge technology to offer tailored solutions across diverse sectors.
Naka-prepack na Software 303.01 10.50 8.08 9.01 5.11 75.63 79.28
2304 IVVD / Invivyd, Inc. Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 117.62 5.25 3.03 4.08 0.97 316.75 79.27
2306 BLNK / Blink Charging Co. Miscellaneous Transportation Equipment 121.14 5.25 1.01 2.72 1.18 131.49 79.26
2307 ALGM / Allegro MicroSystems, Inc.
Allegro MicroSystems, Inc., based in the United States, operates primarily in the semiconductor industry, focusing on designing and manufacturing sensor integrated circuits and semiconductor solutions. The company specializes in technologies critical for automotive applications, including electric and autonomous vehicles, as well as industrial and consumer markets. Key projects often revolve around developing advanced motion control systems, energy-efficient innovations, and safety-enhancing components such as magnetic sensors and power and interface products. Allegro's emphasis on robust research and development allows it to stay at the forefront of microsystems technology, actively contributing to smarter, safer, and more efficient electronic systems across global markets.
Mga Semiconductor at Mga Kaugnay na Device 5,698.20 47.25 30.30 39.19 30.85 26.94 79.26
2310 AYTU / Aytu BioPharma, Inc.
Aytu BioPharma, Inc., headquartered in the United States, operates within the healthcare sector, focusing primarily on the pharmaceutical industry. The company is dedicated to developing and commercializing novel products in areas of significant medical need, including pediatric healthcare and other therapeutic areas. Key projects have included a range of products from prescription medications to wellness products. Notably, Aytu BioPharma has been involved in the commercialization of a distinct therapeutic portfolio aimed at addressing issues such as sleep disorders and allergies. The company's strategy is underscored by its commitment to therapeutic innovations and partnerships geared towards enhancing patient care in underserved markets.
Mga Paghahanda sa Parmasyutiko 14.54 12.60 8.08 9.86 2.35 318.33 79.25
2312 ZVIA / Zevia PBC Mga Bote at Latang Soft Drinks at Carbonated na Tubig 188.49 6.30 2.73 4.96 2.80 77.29 79.24
2315 ISUNQ / iSun, Inc. Mga Semiconductor at Mga Kaugnay na Device 0.03 79.23
2318 TIL / Instil Bio, Inc. Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 182.27 189.00 51.51 121.04 27.00 348.30 79.22
2321 MGX / Metagenomi, Inc. 65.31 12.60 7.07 9.69 1.74 456.90 79.21
2332 RDZN / Roadzen, Inc. Mga Ahente ng Insurance, Broker, at Serbisyo 72.06 5.25 4.04 4.59 0.98 373.20 79.19
2337 TAL / TAL Education Group - Depositary Receipt (Common Stock)
TAL Education Group, based in China, is a prominent player in the global education sector, primarily involved in providing K-12 after-school tutoring services. The company leverages a hybrid model comprising both in-person and online classes, thereby reaching a broad demographic of students across various regions. Key initiatives by TAL Education Group include developing AI-driven educational content and platforms, which significantly enhance personalized learning experiences and operational efficiency. Continuous investment in technological innovation remains a cornerstone of their strategy, aiming to revolutionize the traditional educational paradigms and cater to evolving market demands. As a result, TAL Education Group has established itself as a leading entity in educational technology and service provision, enhancing its capacity to influence educational practices on a scale both nationally and internationally.
Mga Serbisyong Pang-edukasyon 6,421.99 17.69 11.31 13.22 10.62 24.56 79.18
2340 VANI / Vivani Medical, Inc. Electromedical at Electrotherapeutic Apparatus 68.43 7.35 4.04 5.10 1.15 341.56 79.17
2343 USAU / U.S. Gold Corp. Pagmimina ng Metal 166.85 24.68 15.15 19.67 13.13 49.61 79.17
2348 FOUR / Shift4 Payments, Inc. Mga Serbisyo sa Negosyo, Hindi Nauuri sa Ibang Lugar 6,123.48 137.55 81.95 111.46 90.43 23.17 79.14
2349 DWTX / Dogwood Therapeutics, Inc.
Virios Therapeutics is a development-stage biotechnology company focused on advancing novel antiviral therapies to treat diseases associated with a viral triggered abnormal immune response, such as fibromyalgia ('FM').
Mga Paghahanda sa Parmasyutiko 9.48 31.50 10.10 17.34 4.87 249.60 79.14
2352 VTAK / Catheter Precision, Inc.
Catheter Precision, Inc., based in the United States, operates within the medical device industry, focusing on developing innovative technologies for cardiac procedures. The company is renowned for its advanced solutions that assist in the diagnosis and treatment of cardiac arrhythmias. A key project by Catheter Precision is the VIVO System, which utilizes non-invasive techniques to map and diagnose cardiac arrhythmias, providing vital pre-procedural information that enhances the accuracy and outcomes of catheter ablation therapies. This product exemplifies the company’s commitment to improving procedural efficacy and patient safety in electrophysiology labs, positioning Catheter Precision as a pivotal player in the field of cardiac health technology.
Mga Instrumento at Apparatus ng Surgical at Medikal 2.48 39.90 38.38 38.76 2.50 1,463.53 79.13
2355 NOTV / Inotiv, Inc.
Inotiv, Inc., based in the United States, operates within the biopharmaceutical and healthcare sector, primarily focusing on providing drug discovery and development services. The company’s key offerings include nonclinical and analytical drug research, development services, and regulatory consulting, catering to clients in the pharmaceutical, biotechnology, and medical device industries. Inotiv has been actively involved in expanding its service capabilities through strategic acquisitions, such as the purchase of Envigo RMS LLC, which significantly increased its capacity in toxicology research and other preclinical services. This expansion strategy enhances Inotiv’s ability to support its clients from early-stage discovery through preclinical development, underscoring its role as a comprehensive provider in the life sciences field.
Komersyal na Pisikal at Biyolohikal na Pananaliksik 57.89 9.45 2.52 5.61 1.69 232.94 79.12
2356 TARS / Tarsus Pharmaceuticals, Inc. Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 2,470.19 89.25 45.45 75.19 58.58 28.48 79.12
2357 HOTH / Hoth Therapeutics, Inc. Mga Paghahanda sa Parmasyutiko 15.35 5.25 4.04 4.59 1.16 295.69 79.11
2366 ADMA / ADMA Biologics, Inc. Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 4,115.29 36.75 19.43 29.64 17.26 71.83 79.07
2369 LPRO / Open Lending Corporation Lembaga Kredit Pribadi 248.75 7.35 2.52 3.61 2.11 71.68 79.06
2371 VRT / Vertiv Holdings Co Mga Electronic na Bahagi, Hindi Nauuri sa Ibang Lugar 48,699.08 181.65 113.12 156.73 127.55 22.88 79.06
2375 RAPT / RAPT Therapeutics, Inc.
RAPT Therapeutics, Inc., based in the United States, operates within the biotechnology industry, specializing in the discovery and development of oral small molecule therapies for patients suffering from systemic inflammatory diseases and cancer. The company leverages its proprietary discovery platform to target specific molecules that modulate the immune system, focusing notably on TH1 and TH17 driven diseases. Key projects at RAPT include the development of treatments such as FLX475, targeting T cell trafficking for various cancers, and RPT193, aimed at addressing inflammatory diseases like atopic dermatitis. This strategic focus on immune-driven conditions positions RAPT Therapeutics to potentially impact a significant patient demographic across multiple disease areas.
Mga Paghahanda sa Parmasyutiko 188.18 39.90 9.09 24.65 11.38 115.10 79.04
2376 FIS / Fidelity National Information Services, Inc.
Fidelity National Information Services, Inc., based in the United States, is a prominent global provider operating primarily in the financial services technology industry. Commonly known as FIS, the company specializes in offering a wide range of financial products and services, including payment processing, financial software, and banking solutions. With a focus on integrating technology to enhance banking operations, FIS serves a broad spectrum of clients, from local banks to large financial institutions worldwide. Key projects typically involve deploying advanced payment systems, risk management solutions, and developing innovative fintech platforms that facilitate real-time banking capabilities, ensuring the company remains at the forefront of the financial technology evolution.
Mga Serbisyo sa Negosyo, Hindi Nauuri sa Ibang Lugar 36,510.63 105.00 70.70 87.39 69.81 25.16 79.04
2381 CRD.B / Crawford & Company
Crawford & Company, based in the United States, operates primarily in the global claims management industry. The company provides a comprehensive range of services including claims adjustment, third-party claims management, and risk management solutions, aimed at improving operational efficiency and reducing cost for its clients. Crawford has developed specialized expertise in sectors such [as property and casualty insurance, along with services tailored for the automotive and healthcare industries, among others. Notable projects frequently involve large-scale claims processing following natural disasters, sophisticated risk assessments for international firms, and technological innovation like their Crawford TPA Solutions. Crawford’s operations are global, underscoring its role in facilitating business continuity and recovery in diverse markets.
Mga Ahente ng Insurance, Broker, at Serbisyo 533.31 14.70 14.14 14.28 10.59 34.34 79.03
2382 CCOI / Cogent Communications Holdings, Inc.
Cogent Communications Holdings, Inc., based in the United States, is a prominent company within the telecommunications sector, chiefly specializing in providing high-speed Internet access and point-to-point network services. As a significant player in the field of internet service, Cogent's primary business involves offering its services chiefly to small and medium-sized businesses, as well as to other telecommunications companies, net-centric organizations, and enterprises. The corporation operates an extensive fiber-optic network, which spans over 57,400 route miles, serving over 216 markets in 47 countries. A key project for Cogent has been the continual expansion of its network capabilities and the enhancement of data services, aimed at ensuring superior connectivity and reliability for its growing customer base. This strategy not only reinforces Cogent’s infrastructure but also its positioning within the competitive landscape of global internet service providers.
Mga Serbisyo sa Komunikasyon, Hindi Nauuri sa Ibang Lugar 1,818.85 79.80 30.30 52.63 38.23 37.71 79.02
2383 LOCL / Local Bounti Corporation Agricultural Production - Crops 52.50 6.30 5.05 5.61 2.41 136.71 79.01
2386 ICUI / ICU Medical, Inc.
ICU Medical, Inc., based in the United States, operates primarily within the healthcare sector, specializing in the development, manufacture, and sale of innovative medical devices used in vascular therapy, oncology, and critical care applications. The company's key product lines include intravenous products such as IV solutions, infusion therapy sets, and lock devices. ICU Medical is noted for integrating its products with hospital systems to enhance patient safety and improve clinical workflows. Recent strategic projects involve expanding their global footprint and enhancing their product portfolio through acquisitions, such as the purchase of Smiths Medical which significantly boosted their market presence in infusion and vascular access technologies. These initiatives underscore ICU Medical's commitment to advancing medical technology and expanding its influence in critical care environments worldwide.
Mga Instrumento at Apparatus ng Surgical at Medikal 3,151.78 200.55 146.45 179.72 127.66 40.76 79.00
2390 MYO / Myomo, Inc.
Myomo, Inc., headquartered in the United States, is a medical robotics company that operates principally in the healthcare equipment industry. The company specializes in developing and commercializing innovative orthotic devices that enhance the mobility of individuals with neurological disorders and upper limb paralysis. A standout product in their lineup is the MyoPro, a myoelectric arm orthosis, which helps patients regain arm and hand functionality by sensing electrical signals from their muscles to control the device. This technology is pivotal for patients recovering from strokes, spinal cord injuries, and other neuromuscular diseases. Myomo continues to focus on technological advancements in the medical robotics field, aiming to improve patient outcomes and accessibility to advanced orthotic devices.
Mga Orthopedic, Prosthetic, at Surgical Appliances at Supplies 39.67 12.08 2.02 5.41 1.05 419.81 78.99
2394 GAME / GameSquare Holdings, Inc.
GameSquare Holdings, Inc., headquartered in Canada, operates within the burgeoning esports industry, focusing on capitalizing on the intersection of sports, entertainment, and technology. The company's business model revolves around delivering digital marketing services, leveraging its comprehensive network encompassing esports teams, league operations, and content production. Notably, GameSquare successfully bridges traditional marketing strategies with the immersive influence of esports, targeting a predominantly young, tech-savant demographic that is highly attractive to advertisers. Among its prominent ventures, it owns and manages several competitive gaming teams and has established significant partnerships with key industry entities, aiming to innovate and lead in the rapidly evolving esports market landscape.
Mga Serbisyo sa Libangan at Libangan 29.61 3.15 3.03 3.06 0.76 304.39 78.96
2395 TTGT / TechTarget, Inc. 421.07 15.75 10.10 12.58 5.90 113.58 78.96
2397 AMLX / Amylyx Pharmaceuticals, Inc. Mga Paghahanda sa Parmasyutiko 836.73 17.85 8.08 11.86 9.38 26.35 78.95
2398 CRMD / CorMedix Inc.
CorMedix Inc., headquartered in the United States, is a biopharmaceutical company mainly focused on developing and commercializing therapeutic products for the prevention and treatment of infectious and inflammatory diseases. A key project of CorMedix is Neutrolin, a novel anti-infective solution designed for the prevention of catheter-related bloodstream infections (CRBSIs) in patients on hemodialysis due to chronic kidney disease. Neutrolin, which has shown clinical effectiveness, combines an antimicrobial agent and an anticoagulant. This formulation not only aims to significantly reduce the incidence of dangerous infections but also ensures the functional longevity of central venous catheters, thereby addressing a critical medical need in a high-risk patient population.
Mga Paghahanda sa Parmasyutiko 1,106.63 23.10 17.17 20.23 14.83 36.41 78.94
2399 MSFT / Microsoft Corporation
Microsoft Corporation, headquartered in the United States, is a premier entity in the technology sector, primarily focused on software development, cloud computing, and related services. As a global leader, Microsoft operates through three core segments: Productivity and Business Processes, Intelligent Cloud, and More Personal Computing. Key projects include the development and expansion of its Azure cloud services, enhancing the Office 365 productivity suite, and advancing AI capabilities across its product line. The company also invests significantly in research for quantum computing and uses its technologies to support various industries such as healthcare, finance, and retail, ensuring its prominence in both enterprise and consumer markets.
Naka-prepack na Software 3,766,733.46 714.00 427.23 615.98 506.69 21.51 78.94
2400 EPAM / EPAM Systems, Inc.
EPAM Systems, Inc. is a global provider of digital platform engineering and software development services, headquartered in the United States. Positioned primarily in the Information Technology services industry, EPAM has carved out a niche by offering comprehensive consulting, design, and technical capabilities that support the entire software development lifecycle. Key projects often involve complex software engineering, digital and service design solutions, and cloud infrastructure services, targeting clients across industries such as financial services, healthcare, and retail among others. EPAM has also prioritized innovation in artificial intelligence and blockchain technology, reflecting its focus on cutting-edge technological advancements to drive digital transformation strategies for global enterprises.
Mga Serbisyo sa Computer Programming 9,822.55 258.30 172.71 218.92 176.36 24.11 78.93
2401 DIBS / 1stdibs.Com, Inc. Mga Katalogo at Bahay-Kalakal na Nagbebenta sa Pamamagitan ng Pagpapadala 99.68 6.30 6.06 6.12 2.74 122.55 78.93
2406 CCCS / CCC Intelligent Solutions Holdings Inc.
CCC Intelligent Solutions Holdings Inc., based in the United States, operates primarily in the technology sector, focusing extensively on the automotive and insurance industries. The company provides advanced software solutions, leveraging artificial intelligence technologies to streamline processes such as claims management, and repair service facilitation for auto insurers, repairers, and manufacturers. A key project is the development of CCC X data exchange platform, which facilitates connections and communications among a vast network of industry participants, enhancing service delivery efficiencies. CCC Intelligent Solutions significantly contributes to the digitization and automation of workflows, evidenced by its pivotal role in transforming traditional approaches into intelligent, data-driven solutions in its primary sectors.
Naka-prepack na Software 6,418.56 14.70 10.10 12.43 9.90 25.66 78.92
2407 CI / The Cigna Group
The Cigna Group, based in the United States, operates primarily in the health services and insurance industry. This global health service company is dedicated to improving the health, well-being, and peace of mind of those it serves. Cigna's extensive product portfolio includes health insurance, dental insurance policies, Medicare plans, Medicaid, and pharmacy services. One of its notable projects includes collaborating with healthcare providers to develop value-based care models that emphasize improved outcomes for patients at reduced costs. The company focuses on leveraging data and analytics to enhance patient engagement and optimize provider performance, aligning with its strategic aim to transform healthcare on a global scale.
Mga Plano sa Serbisyong Ospital at Medikal 80,211.94 435.75 303.00 367.43 300.87 22.02 78.92
2411 IT / Gartner, Inc.
Gartner, Inc., headquartered in the United~States, is a leading research and advisory company globally recognized in the IT, finance, human resources, legal and compliance, and marketing sectors. The firm specializes in providing essential business insights, advice, and tools for IT, Security and Risk Management, and other business functions, aiding clients in making informed decisions and driving efficient performance in their respective markets. Among its key projects are the Magic Quadrant for research methodologies, which aids stakeholders in evaluating technology and service providers' capabilities, and the Hype Cycle, providing a graphical representation of the maturity and adoption of technologies and applications. These initiatives embody Gartner's commitment to advancing industry standards and expanding business efficacies through comprehensive research and strategic advisory services.
Mga Serbisyo sa Pamamahala 19,292.62 546.20 227.25 332.85 251.19 32.45 78.91
2414 BWIN / The Baldwin Insurance Group, Inc. Mga Ahente ng Insurance, Broker, at Serbisyo 2,257.40 54.60 31.31 42.26 31.67 33.43 78.88
2416 DMAC / DiaMedica Therapeutics Inc. Mga Paghahanda sa Parmasyutiko 246.37 14.70 11.11 12.58 5.71 119.93 78.88
2418 ZTS / Zoetis Inc.
Zoetis Inc., headquartered in the United States, is a global leader in the animal health industry, providing a wide range of veterinary pharmaceuticals and vaccines. The company focuses on both livestock and companion animals, offering products that enhance health, wellness, and performance. Significant projects include the development of innovative medicines and diagnostics, which are critical to advancing veterinary care. Zoetis emphasizes sustainability and responsible operations in its development and manufacturing processes. It also invests heavily in biodevices and genetics, aiming to expand its product offerings and leverage technology to improve animal care on a global scale, thereby reinforcing its industry-leading position and driving long-term shareholder value.
Mga Paghahanda sa Parmasyutiko 69,433.09 241.50 154.53 195.62 156.40 25.05 78.88
2419 DERM / Journey Medical Corporation Mga Paghahanda sa Parmasyutiko 169.35 13.65 10.10 11.73 7.21 62.58 78.87
2426 AFCG / Advanced Flower Capital Inc.
AFC Gamma, Inc. is a specialty finance company based in the United States, primarily engaged in the lending sector for the cannabis industry. Established with the intent to support the growth and operational needs of cannabis-related businesses, AFC Gamma provides tailored and strategic financial solutions, including senior secured loans, to companies in the U.S. cannabis sector which adhere to state law and compliance requirements. The firm utilizes its profound sector-specific expertise to evaluate and manage potential credit risks effectively. AFC Gamma's key projects typically involve providing substantial capital to well-positioned operators in the cannabis industry, aiming to facilitate their expansion, and operational efficiencies, and to enhance their market reach.
Real Estate 105.29 13.65 4.54 7.65 4.66 64.16 78.84
2427 CTXR / Citius Pharmaceuticals, Inc.
Citius Pharmaceuticals, Inc., based in the United States, operates primarily in the biopharmaceutical industry, focusing on developing and commercializing critical care products with a strong emphasis on anti-infectives, cancer care, and unique prescription products. Notably, Citius is advancing a diversified pipeline of products, including Mino-Lok®, an antibiotic lock solution aimed at treating patients with catheter-related bloodstream infections. Another significant project is Halo-Lido, formulated to provide symptomatic relief for hemorrhoids. These initiatives reflect the company's strategic focus on innovative therapies that address significant unmet medical needs in specialized areas of treatment, positioning Citius Pharmaceuticals as a noteworthy player in the development of advanced patient care solutions.
Mga Paghahanda sa Parmasyutiko 19.24 6.30 4.04 5.10 1.33 283.63 78.84
2436 HSCS / HeartSciences Inc. Mga Orthopedic, Prosthetic, at Surgical Appliances at Supplies 3.82 15.75 12.12 13.77 3.38 303.81 78.81
2440 SPT / Sprout Social, Inc. Naka-prepack na Software 928.69 33.60 16.16 23.29 15.79 47.50 78.79
2441 NVGS / Navigator Holdings Ltd.
Navigator Holdings Ltd., based in the United Kingdom, is a prominent player in the international shipping industry, specializing in the maritime transport of liquefied gases. The company operates one of the largest fleets of handysize liquefied gas carriers, and it serves a diverse range of global customers, including major industrial gas companies and energy producers. Navigator Holdings is involved in several key projects that focus on innovation and efficiency in the transportation of petrochemical gases, ammonia, and LPG. A notable initiative includes their collaboration on ethylene export terminals, which strategically position the firm to capitalize on the growing demand for ethylene, particularly in the Asian markets. This strategic approach helps Navigator Holdings to maintain a competitive edge in the liquefied gas shipping sector.
Deep Sea Dayuhang Transportasyon ng Freight 1,078.28 25.20 18.18 20.99 16.09 30.48 78.78
2449 BLFS / BioLife Solutions, Inc.
BioLife Solutions, Inc. is a prominent biotechnology firm based in the United States, specifically operational within the life sciences industry. Founded in 1987, the company has established itself as a leader in the development, manufacture, and sale of bioproduction tools and services, predominantly biopreservation media products for cells and tissues. Central to its offerings is CryoStor®, a series of cryopreservation freeze media designed to mitigate biologic samples' cellular injuries and death during freezing. BioLife’s solutions play a critical role in the regenerative medicine market, supporting developers of biologics, drugs, and cell therapies, from preclinical research to commercial application. The company also extends its expertise to tailor client-specific solutions, which enhances its strategic engagement within the biomedical and pharmaceutical sectors.
Electromedical at Electrotherapeutic Apparatus 1,197.58 35.70 30.30 31.93 25.05 27.55 78.77
2451 ATLX / Atlas Lithium Corporation
Atlas Lithium Corporation, based in the United States, is primarily engaged in the mining and development of lithium resources, which are crucial for renewable energy technologies, particularly electric vehicle batteries. The company focuses on exploring and capitalizing on lithium deposits primarily located in Brazil, a country rich in mineral resources. Among its key projects is the extensive development of high-grade lithium reserves in the eastern part of Minas Gerais state, which is part of Brazil's prolific lithium-rich district. This strategic positioning allows Atlas Lithium to leverage Brazil's resource-rich landscape to address the increasing global demand for lithium, positioning the company as a prominent player in the renewable energy sector.
Pagmimina At Pag-quarry Ng Nonmetallic Minerals, Maliban sa Mga Gatong 100.81 21.00 19.19 19.89 5.37 271.78 78.76
2455 NBIX / Neurocrine Biosciences, Inc.
Neurocrine Biosciences, Inc., based in the United States, operates primarily in the biopharmaceutical industry, focusing on developing treatments for neurological and endocrine-related diseases. Renowned for its research and drug development, Neurocrine Biosciences has made significant strides in creating and commercializing pharmaceutical solutions aimed at addressing complex disorders such as tardive dyskinesia, Parkinson's disease, and endometriosis. Its flagship products include Ingrezza (valbenazine), a novel treatment for movement disorders, and Orilissa (elagolix), targeting pain management in endometriosis. The company's dedication to enhancing neurologic and hormonal therapies through innovative research and strategic collaborations exemplifies its commitment to improving patient care and expanding its market presence.
Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 13,821.39 210.00 125.24 169.76 139.60 21.60 78.75
2458 STGW / Stagwell Inc.
Stagwell Inc., based in the United States, operates primarily within the marketing and communications sector. The company leverages a network of innovative digital-first agencies to deliver data-driven strategies and creative content. Stagwell's portfolio embodies a fusion of marketing insights and cutting-edge technology, enabling effective digital campaigns and marketing services across various media channels. Key projects typically involve large-scale digital transformation initiatives, integration of AI and analytics for precision marketing, and enhancing consumer engagement through virtual reality and other immersive platforms. Their work notably emphasizes the integration of creativity and technology to drive brand growth and improve customer experiences, reflecting a robust understanding of the evolving digital landscape.
Ahensya sa advertising 1,473.37 10.50 6.06 8.36 5.64 48.19 78.74
2459 RRGB / Red Robin Gourmet Burgers, Inc.
Red Robin Gourmet Burgers, Inc. is a United States-based company primarily engaged in the casual dining restaurant industry. Founded in 1969 and headquartered in Greenwood Village, Colorado, the company operates chains that specialize in gourmet burgers and brews. Red Robin has a strong presence across the U.S. with over 500 restaurants comprising both company-owned and franchised locations. The company’s key projects often focus on menu innovation, customer service enhancements, and operational efficiency to enhance guest experience and drive profitability. For instance, initiatives such as digital menu boards, off-premise sales optimizations through better delivery and carry-out services, and investments in technological upgrades have been central to its strategy for navigating the competitive food service landscape.
Mga Restaurant, Kainan, at Lugar ng Kainan 115.90 15.75 6.06 11.02 6.48 69.74 78.73
2464 PIII / P3 Health Partners Inc. Health Services 27.22 21.00 8.08 13.94 8.32 67.35 78.72
2470 UTHR / United Therapeutics Corporation
United Therapeutics Corporation, based in the United States, operates primarily in the biotechnology sector, focusing on the development and commercialization of innovative products to address the unmet medical needs of patients with chronic and life-threatening conditions. The company has carved a niche in the market through its specialized work on pulmonary arterial hypertension (PAH) and other cardiovascular disorders, with key products like Remodulin, Tyvaso, and Orenitram leading its revenue streams. United Therapeutics is also invested in advanced projects such as the development of organ transplantation solutions including the use of xenotransplantation and ex-vivo lung perfusion to increase organ availability, underscoring its commitment to extending the lives and enhancing the quality of life for its patient community.
Mga Paghahanda sa Parmasyutiko 13,779.80 535.50 297.95 386.53 304.76 26.83 78.70
2474 BLNE / Beeline Holdings, Inc. 29.20 4.72 4.54 4.59 1.58 188.68 78.69
2480 FPAY / FlexShopper, Inc.
FlexShopper, Inc., based in the United States, operates primarily in the financial technology and retail sectors, offering lease-to-own (LTO) solutions. This innovative company caters to consumers by providing a range of durable goods such as electronics, furniture, and appliances through a flexible payment model. FlexShopper's key projects include its e-commerce marketplace, which allows customers to shop from a vast selection of products with manageable weekly payments. Furthermore, the company has developed proprietary LTO payment and processing systems that facilitate seamless transactions between merchants and consumers, enabling access to goods for those with limited credit availability. Through these endeavors, FlexShopper positions itself as a facilitator of accessible consumer financing.
Pagrenta at Pagpapaupa ng Kagamitan, Hindi Nauuri sa Ibang Lugar 2.62 2.52 2.55 0.69 264.34 78.67
2485 LAKE / Lakeland Industries, Inc.
Lakeland Industries, Inc., based in the United States, is a prominent player in the industrial protective clothing industry. The company specializes in the design and manufacture of a wide array of safety garments, including chemical protective suits, firefighting turnout gear, and disposable protective clothing. These products are essential in safeguarding workers across various sectors such as oil and gas, chemical, and emergency services against potential hazards associated with their working environments. Lakeland Industries emphasizes innovation and global distribution, extending its market presence across North America, Europe, Latin America, and Asia. The company's commitment to safety, along with its ongoing investment in technology and expansion into new markets, underscores its strategic approach to maintaining a leading position in the protective apparel market.
Mga Orthopedic, Prosthetic, at Surgical Appliances at Supplies 144.90 28.35 23.23 25.50 15.19 67.43 78.64
2487 PTON / Peloton Interactive, Inc.
Peloton Interactive, Inc., based in the United States, operates primarily in the health and fitness industry, specializing in interactive fitness products. Founded in 2012, it has dramatically reshaped home fitness through its advanced equipment, primarily indoor cycling bikes and treadmills integrated with large touchscreen displays that stream live and on-demand fitness classes. Peloton's key projects include expanding its product ecosystem and enhancing its subscription-based digital content offerings. The company has successfully leveraged technology to create a community-driven platform that connects users with professional instructors. Peloton's strategic focus includes global expansion, technological innovation, and enhancing user engagement, as it aims to lead in the connected fitness market amidst growing competition.
Barang Olahraga dan Atletik, Tidak Diklasifikasikan di Tempat Lain 3,086.73 21.00 4.04 9.68 7.60 27.47 78.64
2492 QNRX / Quoin Pharmaceuticals, Ltd. - Depositary Receipt (Common Stock)
Quoin Pharmaceuticals Ltd. is a biopharmaceutical company based in Ireland, primarily engaged in the development of innovative therapeutic products. The company focuses on addressing rare and severe dermatological conditions, aiming to fulfill unmet medical needs. A key project includes QRX003, a lotion formulated to treat Netherton Syndrome, a life-threatening genetic disorder. Additionally, Quoin Pharmaceuticals is developing QRX004 for the treatment of dystrophic epidermolysis bullosa, another rare genetic skin disorder that can cause severe blistering. The firm's strategy revolves around leveraging novel therapeutic pathways and advanced technologies to enhance patient care in niche markets with considerable unaddressed medical demands.
Mga Paghahanda sa Parmasyutiko 4.34 31.50 25.25 28.05 7.85 257.32 78.63
2496 INGM / Ingram Micro Holding Corporation 4,598.25 34.65 19.19 24.89 19.57 27.11 78.60
2497 VXRT / Vaxart, Inc. Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 73.25 4.20 2.02 3.06 0.32 78.59
2501 ACCO / ACCO Brands Corporation
ACCO Brands Corporation, based in the United States, is a leading player in the office products industry globally. The company designs, manufactures, and markets a wide range of traditional and computer-related office products and supplies, including binders, staplers, shredders, and whiteboards under well-known brands such as Mead, Swingline, and Kensington. Operational since 1903, ACCO Brands has focused on expanding its product portfolio and market reach through strategic acquisitions, notably the purchase of General Binding Corporation in 2005 and MeadWestvaco's Consumer & Office Products division in 2012. These acquisitions have enabled ACCO to bolster its presence in key markets and enhance its product lineup, reinforcing its position as a dominant supplier to the office and school supplies sector.
Blankbooks, Looseleaf Binders, And Bookbinding 368.23 11.55 6.06 8.84 4.02 120.18 78.57
2514 BWEN / Broadwind, Inc.
Broadwind, Inc. is an American company based in Cicero, Illinois, primarily engaged in the heavy fabrication, gearing, welding, and assembly of specialized components used in the energy, mining, and infrastructure sectors. Established to provide engineered solutions to the increasingly complex needs of these industries, Broadwind actively participates in the renewable energy market, particularly focusing on manufacturing parts for wind turbines. Key projects include fabricating wind towers and offering precision gearing systems essential for wind power and other industrial applications. The company also explores innovations geared towards enhancing efficiency and reducing the environmental footprint of energy production, aligning with global sustainability goals. This strategic direction allows Broadwind to position itself favourably within the growing clean technology and renewable energy markets, catering to both domestic and international demands.
Nonferrous Foundries (castings) 48.85 6.30 3.03 4.42 2.10 108.49 78.52
2515 TRAW / Traws Pharma, Inc. Mga Paghahanda sa Parmasyutiko 9.96 1.40 10,755.68 78.52
2518 REPX / Riley Exploration Permian, Inc.
Riley Exploration Permian, Inc., based in the United States, operates primarily within the oil and natural gas sector, focusing on exploration, development, and production activities. Central to its operations are its extensive projects located in the Permian Basin of Texas, where the company emphasizes a strategy of growth through the drilling and development of its low-risk, conventional reservoirs. Riley Exploration Permian is committed to increasing its reserves and production through the application of modern technology and sustainable practices, aiming to maximize shareholder value while maintaining high standards of environmental and operational safety. This strategic focus facilitates robust financial performance and contributes to the company's strong positioning in the energy industry.
Crude Petroleum at Natural Gas 645.05 69.30 60.60 64.26 29.26 119.62 78.51
2521 CDZI / Cadiz Inc.
Cadiz Inc. is an American land and water resource development company headquartered in Los Angeles, California. Positioned primarily in the environmental and water supply industries, the company's flagship project involves the storage and supply of water in California's Mojave Desert region. Notoriously known as the Cadiz Water Project, this initiative aims to capture and conserve billions of gallons of groundwater that would otherwise evaporate, providing a sustainable water source for Southern California’s communities and agricultural businesses. Additionally, Cadiz Inc. explores and has developed other resource management ventures that align with sustainable practice models, addressing the critical needs in regions with constrained water supplies. The company's strategic projects continue to stir public, regulatory, and scientific dialogue given their significant environmental implications and contributions to state water resource management.
Supply ng Tubig 293.60 15.75 10.10 12.75 3.58 255.65 78.50
2523 BBNX / Beta Bionics, Inc. 818.88 31.50 17.17 24.14 18.84 28.13 78.49
2529 MDLZ / Mondelez International, Inc.
Mondelez International, Inc., based in the United States, is a global leader in the snack industry, renowned for producing branded cookies, chocolates, gum, and candy. It is the parent company to several iconic brands including Oreo, Cadbury, and Trident. As part of its growth strategy, Mondelez focuses on expanding its market through innovative product launches and strategic acquisitions that enhance its global presence and product portfolio. Recent key projects include advancing its sustainability initiatives, notably in sourcing and packaging, and leveraging digital transformation to strengthen its supply chain and consumer engagement. These efforts are aimed at aligning with evolving consumer preferences and enhancing operational efficiency.
Pagkain At Mga Kamag-anak na Produkto 79,497.57 92.40 58.58 75.19 61.44 22.36 78.46
2530 MGM / MGM Resorts International
MGM Resorts International, based in the United States, operates primarily in the hospitality and entertainment sector, specifically within the gaming industry. As a leading global company, MGM Resorts owns and manages a diversified portfolio of properties including destination resort brands, residential properties, and upscale casinos. Key projects underline its strategic expansion and innovation drive, such as the development of integrated resorts in key markets like Japan and the advancement of its online betting platform. Further, the company has been active in enhancing its sustainability practices and community-oriented projects. This overall approach not only amplifies its core gaming and hospitality operations but also strengthens its market presence and financial prowess in global territories.
Mga Hotel at Motel 10,802.91 60.90 37.37 49.33 39.69 24.27 78.46
2532 FLS / Flowserve Corporation
Flowserve Corporation, based in the United States, is a leading provider within the industrial engineering sector, primarily specializing in the manufacture and service of comprehensive flow control systems. Its offerings are critical to infrastructure and processes in industries like energy, oil, and gas. With a focus on technology-driven solutions, Flowserve manages extensive operations globally, delivering products such as pumps, valves, seals, and end-to-end mechanical services. These are integrated into key projects that enhance efficiency and system longevity for their diverse clientele. The corporation's emphasis on sustainable manufacturing practices further reinforces its commitment to technological innovation and operational excellence in addressing complex fluid motion and control challenges.
Pumps and Pumping Equipment 7,005.85 79.80 60.60 67.83 53.66 26.41 78.46
2534 CAH / Cardinal Health, Inc.
Cardinal Health, Inc., based in the United States, is a global, integrated healthcare services and products company, operating primarily in the healthcare sector. It specializes in the distribution of pharmaceuticals and medical products, serving over 100 countries. Key projects and initiatives typically focus on improving supply chain efficiency, pharmaceutical distribution, medical segment services, and patient care optimization. The company plays a crucial role in healthcare, affecting nearly every facet of the industry, from hospital systems and pharmacies to clinical laboratories and physician offices. Cardinal Health is dedicated to providing cost-effective solutions and is actively involved in the ongoing modernization of healthcare infrastructure to meet regulatory standards and enhance patient care.
Mga Droga, Mga Pagmamay-ari ng Droga, at Iba't-ibang mga Durugista 35,558.42 213.15 153.63 184.85 148.78 24.28 78.44
2537 PPSI / Pioneer Power Solutions, Inc. Power, Distribution, and Specialty Transformers 42.38 12.60 9.09 10.71 3.79 180.37 78.43
2539 RCAT / Red Cat Holdings, Inc.
Red Cat Holdings, Inc., based in the United States, operates primarily in the aerospace sector, specifically focusing on developing, manufacturing, and distributing unmanned aerial vehicles (UAVs) and drone technologies. The company's portfolio is diversified across various functions, including training, distribution, and software solutions tailored for government, commercial, and consumer markets. A significant aspect of Red Cat's operations includes innovative drone technology with applications in military, public safety, and infrastructure sectors, showcasing a strong emphasis on enhancing UAV operability, safety, and data analytics capabilities. Its key projects often revolve around technology integration, advancing UAV analytics, and expanding into strategic markets, positioning itself as a dynamic contributor to the evolving aerospace landscape.
Naka-prepack na Software 881.18 16.80 12.12 14.62 8.94 63.44 78.43
2541 SDRL / Seadrill Limited
Seadrill Limited, headquartered in Bermuda, operates primarily in the offshore drilling industry. The company specializes in providing deepwater drilling services to the oil and gas sector worldwide. Utilizing a fleet that includes drillships, jack-up rigs, and semi-submersibles, Seadrill manages projects that involve complex exploratory and developmental drilling. Key projects often target ultra-deepwater regions and harsh environments, where the company leverages its technological expertise and operational safety processes. Over the years, Seadrill has established a strong reputation based on its innovative approach to tackling demanding drilling requirements, ensuring efficient resource extraction for its global clientele while adhering to stringent environmental and safety standards.
1,986.23 84.00 23.23 40.54 31.91 27.02 78.43
2543 OOMA / Ooma, Inc. Mga Serbisyo sa Pagproseso ng Computer at Paghahanda at Pagproseso ng Data 356.53 21.00 16.16 18.23 12.92 40.68 78.42
2546 INSE / Inspired Entertainment, Inc.
Inspired Entertainment, Inc., based in the United States, operates primarily within the gaming technology industry. It specializes in the creation and distribution of digital games and networks that cater to both mobile and land-based gaming markets globally. Key offerings include virtual sports, server-based gaming systems, and interactive gaming. Inspired Entertainment has strategically focused on extending its digital footprint, exemplified by its audio-visual virtual sports products, which are geared not only toward traditional gambling venues but also towards an expanding online casino presence. The company emphasizes integrating technology and entertainment to provide innovative gaming solutions, aiming to enhance user experience and meet diverse market demands across various jurisdictions. This approach underlines its commitment to shaping the future landscape of interactive and virtual gaming.
Naka-prepack na Software 250.30 21.00 10.10 13.60 9.30 46.24 78.42
2547 VG / Venture Global, Inc. Komunikasyon sa Telepono, Maliban sa Radiotelephone 31,525.00 21.00 12.12 16.83 13.00 29.36 78.41
2551 LPLA / LPL Financial Holdings Inc.
LPL Financial Holdings Inc., based in the United States, operates as a leading financial services company in the investment advisory sector. The firm primarily provides technology, brokerage, and investment advisory services through its subsidiaries. It catifies solutions for financial professionals, including independent financial advisors and financial institutions, facilitating the management of wealth and investment strategies. A key component of LPL Financial's business model is its comprehensive platform, which offers proprietary technology, brokerage, and investment advisory services. This infrastructure supports a range of financial products including stocks, bonds, and mutual funds, helping advisors manage client portfolios efficiently while adhering to compliance standards. This model has positioned LPL Financial as a pivotal player in the financial services industry, enabling scalable operations and robust advisor support.
Security At Commodity Brokers, Dealers, Exchanges, At Serbisyo 29,159.32 514.50 404.00 454.09 364.48 24.51 78.39
2554 MG / Mistras Group, Inc.
Mistras Group, Inc., headquartered in Princeton Junction, New Jersey, USA, operates primarily in the industry of asset protection solutions, specializing in evaluating the structural integrity and reliability of critical energy, industrial, and public infrastructure. Established as a key player in non-destructive testing (NDT), Mistras Group integrates advanced technology and software analytics to offer maintenance and inspection services designed to ensure operational safety and prolong the lifespan of significant assets. Noteworthy endeavors include comprehensive integrity and maintenance projects for oil, gas, and nuclear sectors, as well as supporting infrastructure assessments following natural disasters. These efforts underscore Mistras' commitment to supporting safe and efficient operational standards in high-stakes environments.
Engineering Services 301.50 15.75 11.62 13.43 9.56 40.48 78.38
2556 APO / Apollo Global Management, Inc.
Apollo Global Management, Inc., based in the United States, is a prominent player in the alternative asset management sector. The company specializes in credit, private equity, and real assets investments. Since its inception in 1990, Apollo has cultivated a robust track record of leveraging distressed assets and companies to generate substantial returns. Key projects often involve sizeable corporate buyouts, real estate deals, and substantial loan originations. Apollo's strategic approach focuses on complex transactions and opportunities that require intensive operational involvement. The company's global influence is marked by significant assets under management, making it a pivotal entity in financial markets, adept at navigating diverse economic conditions while maximizing value creation across its extensive investment portfolio.
Payo sa Pamumuhunan 77,926.83 186.90 155.54 168.57 136.23 23.70 78.37
2558 EXLS / ExlService Holdings, Inc.
ExlService Holdings, Inc., based in the United States, operates primarily within the business process management (BPM) and analytics services industry. The company focuses on leveraging digital technologies and analytics to offer services aimed at operational excellence and transformation in businesses heavily vested in industries like insurance, healthcare, banking, and financial services. Key projects typically encompass integrated operations management, advanced analytics, automation, and cloud-based solutions. ExlService Holdings embraces a global delivery model, utilizing its extensive network across the United States, Europe, and Asia to provide strategic solutions that enhance competitiveness and foster growth for its clients. Its innovative approach helps clients navigate the complexities of scaling, digital operation, and compliance within rapidly changing markets.
Mga Serbisyo sa Negosyo, Hindi Nauuri sa Ibang Lugar 7,083.27 58.80 52.52 55.66 43.78 27.17 78.37
2559 AMPY / Amplify Energy Corp.
Amplify Energy Corp. is an independent oil and natural gas company based in the United States, with its headquarters located in Houston, Texas. The company primarily operates in the exploration, development, and production of oil and gas properties. A significant aspect of Amplify Energy's operations includes its key projects in the Rockies, offshore California, East Texas/North Louisiana, and South Texas, which collectively encompass a diverse spectrum of hydrocarbon-producing regions. The company focuses on maximizing the value of its onshore and offshore assets through operational improvements and efficient management practices, and is known for employing advanced recovery techniques and horizontal drilling to optimize production and reserve recovery.
Crude Petroleum at Natural Gas 164.41 11.55 6.06 8.67 4.07 113.28 78.37
2561 EQT / EQT Corporation
EQT Corporation, based in the United States, is a prominent player in the natural gas industry, primarily focusing on natural gas production in the Appalachian Basin. As the largest natural gas producer in the United States, the company leverages advanced horizontal drilling technology to optimize resource extraction from the Marcellus and Utica shales, two of the most prolific natural gas reservoirs in North America. Key projects include the ongoing development of these shale formations, utilizing sustainable practices and innovative technologies to enhance production efficiency and environmental safety. EQT Corporation strategically combines operational excellence with a commitment to reducing emissions, aligning with evolving regulatory and market conditions to sustain its leadership in the natural gas sector.
Crude Petroleum at Natural Gas 32,351.43 77.70 38.21 63.11 51.84 21.69 78.36
2562 NCLH / Norwegian Cruise Line Holdings Ltd.
Norwegian Cruise Line Holdings Ltd. is a leading global cruise company headquartered in the United States, specifically incorporated in Bermuda. It operates primarily in the leisure and travel industry, specializing in cruising services and vacation packages. The company is known for its innovative approach to cruise experiences across its three major cruise brands: Norwegian Cruise Line, Oceania Cruises, and Regent Seven Seas Cruises. These brands offer itineraries to various global destinations, catering to a wide range of consumer tastes and demographics. Key projects have focused on expanding its fleet and enhancing onboard amenities, with a strong commitment to environmental sustainability and technology upgrades to improve operational efficiency and guest satisfaction.
Transportasyong Tubig 11,098.86 42.00 23.23 30.29 24.84 21.84 78.36
2567 SMLR / Semler Scientific, Inc.
Semler Scientific Inc. adalah perusahaan yang berspesialisasi dalam pengembangan dan komersialisasi teknologi dan produk eksklusif yang membantu penyedia layanan kesehatan dalam mengevaluasi dan mengelola penyakit kronis.
Electromedical at Electrotherapeutic Apparatus 405.72 106.05 95.95 99.96 29.64 237.25 78.35
2572 TMC / TMC the metals company Inc. Pagmimina ng Metal 2,136.70 12.60 6.56 8.92 5.36 65.89 78.33
2573 NXTC / NextCure, Inc.
NextCure, Inc., headquartered in the United States, is a biopharmaceutical company focused mainly on discovering and developing novel immunotherapies that target cancer and other immune-related diseases. Operating within the biotechnology industry, NextCure is pioneering research with its proprietary FIND-IO platform, which systematically profiles molecular interactions to identify new targets involved in immuno-oncology. Among its key projects, the development of NC318, a novel immunomedicine targeting the Siglec-15 immune pathway, stands out as a primary focus. This project, along with others like NC410, which aims to modulate immune response to combat cancer, positions NextCure at the forefront of next-generation cancer therapy innovations. Their strategic approach combines cutting-edge technology and rigorous science to address unmet medical needs in oncology.
Mga Paghahanda sa Parmasyutiko 11.76 21.00 15.15 17.85 5.03 254.87 78.33
2583 KZR / Kezar Life Sciences, Inc.
Kezar Life Sciences, Inc., based in the United States, operates within the biotechnology sector focusing on the discovery and development of novel treatments for autoimmune diseases and cancer. Since its inception, the company has been committed to advancing healthcare through breakthrough scientific research. A key project involves its innovative drug candidate, KZR-616, which is designed as a selective immunoproteasome inhibitor with potential applications across multiple autoimmune diseases. In addition, Kezar Life Sciences explores the development of small molecules targeting protein secretion pathways for various malignancies. Their strategic approach combines cutting-edge science with targeted therapies to address significant unmet medical needs in both disease areas.
Mga Paghahanda sa Parmasyutiko 28.90 18.90 7.07 12.75 3.95 222.78 78.29
2586 DASH / DoorDash, Inc.
DoorDash, Inc., based in the United States, operates within the technology-driven logistics and food delivery industry. The company provides a platform that facilitates door-to-door delivery services, where users can order food from local and chain restaurants. It leverages innovative logistical technology to offer efficient and convenient solutions for users and has expanded its services to include the delivery of groceries and other essential items. Key projects include expanding into suburban markets and integrating autonomous vehicles and drones into its delivery fleet to cut costs and improve delivery times. DoorDash's strategic initiatives focus on enhancing its technological infrastructure and exploring new markets to maintain its competitiveness and market share.
Mga Serbisyo sa Negosyo, Hindi Nauuri sa Ibang Lugar 104,705.17 378.00 181.13 296.28 245.25 20.80 78.28
2587 ADUS / Addus HomeCare Corporation
Addus HomeCare Corporation, based in the United States, operates primarily in the healthcare industry, specializing in providing comprehensive home-based health and wellness services. Founded in 1979, the company focuses on offering personal care, home health, and hospice services, predominantly serving elderly and disabled individuals. Addus strengthens its market position through both organic growth and strategic acquisitions, aimed at expanding its geographic footprint and service offerings across multiple states. Key projects include enhancing its home health and hospice segments, aiming to leverage technological advancements to improve service delivery and patient outcomes, and integrating acquired operations to streamline efficiencies and capitalize on market opportunities.
Home Health Care Services 2,111.66 168.00 112.11 143.54 115.17 24.61 78.28
2590 XHLD / TEN Holdings, Inc. 11.23 8.40 8.08 8.16 0.32 2,450.80 78.26
2591 HIVE / HIVE Digital Technologies Ltd.
HIVE Digital Technologies Ltd., based in Canada, operates primarily within the cryptocurrency mining sector. It focuses on the mining of digital currencies like Bitcoin and Ethereum, utilizing green energy to power its operations, thereby addressing environmental concerns associated with crypto-mining. By harnessing renewable energy sources, HIVE aims to achieve a lower carbon footprint compared to conventional mining practices. In addition to its core mining activities, the company is also involved in the development of data center infrastructure essential for its mining operations. This strategic approach not only enhances its operational efficiency but also bolsters its capacity to scale in a rapidly evolving digital currency landscape.
Mga Serbisyo sa Pananalapi 602.76 4.57 3.66 4.25 2.95 44.16 78.26
2593 NFGC / New Found Gold Corp.
New Found Gold Corp. is a Canadian-based exploration company primarily engaged in the business of mineral exploration. Positioned in the gold sector, the company focuses on identifying and developing valuable gold deposits. Notably, its flagship project is the Queensway Project, located in Newfoundland and Labrador. This project has gained significant attention due to its promising high-grade gold discoveries along major fault zones, which are strategically extensive and offer potential for substantial resource expansion. New Found Gold Corp. leverages advanced geological and exploration technologies to drive its exploration efforts, aiming to establish and expand its presence within the gold mining industry's competitive landscape.
Pagmimina ng Ginto At Pilak 446.84 3.20 2.17 2.80 1.95 44.15 78.26
2595 INVA / Innoviva, Inc.
Innoviva, Inc. is a diversified holding company headquartered in the United States, primarily engaged in the healthcare sector. The company focuses on the acquisition and management of royalties from biopharmaceutical products and the management of a broad portfolio of pharmaceuticals. Innoviva strategically invests in entities that are involved in the discovery and development of new medical therapies, leveraging its capital and expertise in the industry to maximize shareholder value. A key aspect of Innoviva's business model is its acquisition of royalty income generated by respiratory assets commercialized by GlaxoSmithKline, which includes notable products such as Relvar/Breo Ellipta and Anoro Ellipta. This approach enables Innoviva to benefit from substantial recurring revenue without the direct costs associated with drug development and commercialization.
Mga Paghahanda sa Parmasyutiko 1,287.31 57.75 29.29 41.82 20.43 104.75 78.25
2598 CCK / Crown Holdings, Inc.
Crown Holdings, Inc., based in the United States, is a global leader in the manufacturing of packaging products for consumer goods. Predominantly operating in the metal packaging industry, the company catizes a broad range of products including beverage cans, food containers, and metal closures. Crown Holdings has significantly expanded its global footprint through strategic acquisitions and the establishment of advanced manufacturing facilities. Key projects have included investments in technology to enhance the sustainability and recyclability of its products, responding to increasing consumer and regulatory demands for environmentally friendly packaging solutions. These initiatives are designed to bolster the company's market position by leveraging innovation to meet the evolving needs of both global and local markets.
Metal Cans 11,435.03 147.00 105.36 126.11 99.38 26.94 78.24
2599 SEMR / Semrush Holdings, Inc. Naka-prepack na Software 1,171.66 13.65 9.09 11.05 7.90 39.78 78.23
2600 SAFE / Safehold Inc.
Safehold Inc. is a real estate investment company based in the United States, specializing in the acquisition, management, and capitalization of ground leases. The company focuses on revolutionizing the traditional real estate ownership model by creating a more efficient way for property owners to unlock capital while retaining operational control. Safehold’s groundbreaking approach involves purchasing the land beneath prime commercial buildings and leasing it back to the owners, thereby providing them with liquidity and investment opportunities while Safehold retains a long-term interest in the properties. This unique business model aims to generate stable, long-term income streams while promoting growth in shareholder value through strategic ground lease innovations. Key projects typically involve high-value, urban core real estate in major U.S. cities, positioning Safehold as a pioneering entity in the commercial real estate sector.
Lessors of Real Property, Not Elsewhere Classified 1,180.84 29.40 16.16 21.76 16.46 32.12 78.22
2601 DDI / DoubleDown Interactive Co., Ltd. - Depositary Receipt (Common Stock)
DoubleDown Interactive Co., Ltd. is a reputable game developer based in South Korea, predominantly engaged in the digital interactive entertainment industry. Renowned for its flagship project, DoubleDown Casino, one of the largest online social casino games globally, the company has effectively captured a substantial audience by providing a diverse range of gambling-style games accessible primarily through mobile platforms and social media sites. Its market approach emphasizes free-to-play games, monetized through in-app purchases and advertising, serving both casual and dedicated players. The company continually enhances its gaming portfolio by developing new titles and improving existing ones with innovative features and content to maintain user engagement and competitive standing in the rapidly evolving online gaming sector.
Mga Serbisyo sa Pagproseso ng Computer at Paghahanda at Pagproseso ng Data 477.70 23.10 16.16 19.79 9.65 105.27 78.22
2602 BTCT / BTC Digital Ltd. 10.75 5.05 7.77 2.56 206.50 78.21
2604 EWCZ / European Wax Center, Inc. Personal na Serbisyo 185.80 15.75 4.04 6.92 4.29 61.53 78.21
2605 MCS / The Marcus Corporation
The Marcus Corporation, based in the United States, operates primarily within the hospitality and entertainment industries. Established in 1935 and headquartered in Milwaukee, Wisconsin, the company primarily engages through two distinct divisions: Marcus Theatres and Marcus Hotels & Resorts. Marcus Theatres is one of the largest cinema chains in the United States, known for enhancing movie-going experiences with special features and amenities. Marcus Hotels & Resorts, on the other hand, owns and manages a diverse portfolio of hotels and resorts, specializing in providing upscale accommodation and services. The corporation focuses on strategic growth through innovative offerings and excellent customer service, strengthening its market presence across its operating sectors. This strategy not only expands its footprint but also enhances shareholder value through sustained revenue growth and profitability.
Motion Picture Theaters 483.44 28.35 24.24 25.50 15.44 65.05 78.20
2606 DVLT / Datavault AI Inc. Mga Semiconductor at Mga Kaugnay na Device 31.54 11.55 3.03 7.14 0.36 1,861.54 78.19
2608 USPH / U.S. Physical Therapy, Inc. Health Services 1,260.27 118.65 98.98 108.32 82.89 31.02 78.19
2610 KGS / Kodiak Gas Services, Inc.
Kodiak Gas Services, Inc., based in the United States, operates within the energy sector, primarily focusing on providing natural gas compression services. The company plays a critical role in supporting North American energy infrastructure by offering solutions tailored for efficient gas compression, a vital process in natural gas extraction and transportation. Kodiak’s services ensure that natural gas remains a viable and efficient energy source by optimizing the delivery system's performance and reliability. The firm has engaged in significant projects that emphasize innovation and environmental responsibility, aiming to reduce operational emissions and enhance the sustainability of natural gas operations. Known for its commitment to technological advancement and customer service, Kodiak Gas Services has established itself as a key player in maintaining the stability and efficiency of energy supply chains.
Paghahatid ng Natural Gas 3,138.75 50.40 37.37 45.34 35.79 26.66 78.18
2613 BTSG / BrightSpring Health Services, Inc. Home Health Care Services 43.05 25.25 29.28 23.69 23.76 78.17
2616 JBS / JBS N.V.
JBS S.A. is a global leader in the meat processing industry, headquartered in São Paulo, Brazil. It operates in the processing of beef, pork, lamb, and chicken, and its derivatives, including leather. JBS is one of the largest food companies in the world by sales, and it also has extensive involvement in the production of value-added and packaged meat products. The company has pursued aggressive growth strategies, including significant acquisitions such as the purchase of Pilgrim's Pride in the United States and Moy Park in Europe. JBS has also invested in sustainability projects, aiming to reduce greenhouse gas emissions and increase the use of renewable energy in its operations, positioning itself as a forward-thinking player in a resource-intensive industry.
35,966.76 27.30 19.19 21.35 16.21 31.66 78.15
2617 LBTYK / Liberty Global Ltd.
Liberty Global Ltd., based in London, United Kingdom, operates as a multinational telecommunications company. It stands as one of the world’s leading converged video, broadband, and communication companies, primarily focusing on operations in Europe, including key markets like the United Kingdom, Switzerland, and Ireland. Liberty Global is involved in significant projects that enhance broadband penetration and network capacity, such as substantial upgrades to its infrastructure and the expansion of its gigabit-speed internet services. Additionally, the company actively engages in strategic acquisitions and partnerships to bolster its market presence and technological capabilities, aiming to leverage advancements in 5G technology and expand its offerings in mobile telephony and business-to-business telecommunications solutions.
Cable at Iba pang Pay Television Services 3,878.42 37.04 10.08 17.20 11.95 43.94 78.14
2621 STOK / Stoke Therapeutics, Inc.
Stoke Therapeutics, Inc., based in the United States, operates primarily within the biotechnology sector, focusing on pioneering treatments for genetic diseases caused by protein deficiency. The company employs its proprietary technology, TANGO (Targeted Augmentation of Nuclear Gene Output), aimed at precisely upregulating protein expression directly at the level of RNA. This innovative approach targets a range of severe and rare diseases, including Dravet syndrome, a severe form of epilepsy. Stoke Therapeutics is actively engaged in the research and development phase, pushing forward in clinical trials to deliver therapies that address unmet medical needs in the genetic disorder spectrum, thereby highlighting its commitment to advancing healthcare through cutting-edge genetic research.
Mga Paghahanda sa Parmasyutiko 1,081.34 36.75 15.15 24.71 19.76 25.03 78.11
2622 MNDR / Mobile-health Network Solutions 67.20 64.64 65.28 1.00 6,708.51 78.10
2626 AIRJ / AirJoule Technologies Corporation 277.42 12.60 8.84 10.58 4.60 130.56 78.09
2628 PCSA / Processa Pharmaceuticals, Inc. Mga Paghahanda sa Parmasyutiko 7.62 2.10 2.02 2.04 0.19 978.79 78.08
2638 NDRA / ENDRA Life Sciences Inc. Electromedical at Electrotherapeutic Apparatus 3.08 48.30 46.46 46.92 4.10 1,047.72 78.04
2645 SONM / Sonim Technologies, Inc.
Sonim Technologies, Inc., based in the United States, operates within the telecommunications sector, specializing in the design and manufacture of ultra-rugged mobile devices, including smartphones and feature phones, tailored to meet the stringent demands of enterprise customers in industries such as construction, public safety, and manufacturing. Renowned for their durability and reliability, Sonim's devices often incorporate enhanced features such as long battery life, waterproof capabilities, and resistance to extreme temperatures. Additionally, the company provides software and accessories that complement its mobile offerings, integrating solutions to enhance productivity and connectivity for workers in harsh environments. As a leader in rugged communications technology, Sonim continues to innovate and expand its portfolio, catering to the unique requirements of task-specific telecommunications.
Aparato ng Telepono at Telegrapo 6.10 0.59 1,296.54 78.01
2652 STIM / Neuronetics, Inc.
Neuronetics, Inc., based in the United States, operates primarily within the medical device industry, focusing on pioneering treatments for psychiatric disorders. A notable project of Neuronetics is the development of its proprietary NeuroStar Advanced Therapy system, a non-invasive treatment that utilizes transcranial magnetic stimulation (TMS) technology to alleviate depression. Established with an intention to innovate solutions for mental health issues, the company notably addresses conditions that are often resistant to conventional treatments. Neuronetics’ role in advancing neuromodulation therapies positions it as a key player in the mental health sector, contributing to broader healthcare objectives by providing clinically significant improvements in patient outcomes through technology-driven treatments.
Mga Instrumento at Apparatus ng Surgical at Medikal 220.16 7.35 5.56 6.63 3.33 98.80 77.99
2655 PSQH / PSQ Holdings, Inc. Advertising 76.18 8.40 3.03 5.61 1.66 235.95 77.98
2656 DDOG / Datadog, Inc.
Datadog, Inc., based in the United States, operates primarily in the software industry, delivering a robust monitoring and analytics platform. This platform aids businesses in improving agility, increasing efficiency, and providing end-to-end visibility across their applications and business systems. Datadog seamlessly aggregates data from servers, databases, tools, and services into a unified view of IT infrastructure. Notably, their key projects often include innovations in APM (application performance monitoring), infrastructure monitoring, log management, and cloud observability. These initiatives are designed to support businesses in optimizing operational performance and ensuring high levels of user satisfaction. Datadog emphasizes collaboration across development, operations, and business teams through their data-driven insights.
Naka-prepack na Software 47,316.57 210.00 106.05 164.44 136.68 20.32 77.97
2660 XP / XP Inc.
XP Inc. is a financial services company based in Brazil that specializes in investment brokerage and financial management services for clients. As a major player in the Latin American financial sector, XP Inc. offers extensive brokerage services, facilitating substantial trading volumes across equity, fixed income, and derivatives markets. The firm also delivers a comprehensive suite of wealth management services, including portfolio management, financial advisory, and an array of investment products aimed primarily at retail investors and institutional clients. Key projects executed by XP Inc. include the expansion of their technology platform to enhance user experience and the development of personalized investment solutions that leverage data analytics to tailor offerings to individual client needs. The company's strategic initiatives focus on broadening its market reach and leveraging technological innovations to solidify its presence in the competitive financial landscape.
Mga Security Broker, Dealer, at Flotation Company 9,743.72 27.30 19.19 22.95 18.14 26.48 77.96
2661 CNK / Cinemark Holdings, Inc.
Cinemark Holdings, Inc., based in the United States, operates as a leader in the motion picture exhibition industry. Within its primary business, the company manages a vast network of theatres in various international markets including North and South America. Cinemark focuses on delivering an enhanced cinematic experience through state-of-the-art technology and innovations in theatre design, seating, and concession items. Key projects have included the rollout of Luxury Lounger reclining seats across its cinemas, enhancements in digital projection systems, and the expansion of XD premium large format screens. These initiatives are part of Cinemark's strategy to bolster attendance and increase revenue per customer, securing its position in a competitive market.
Motion Picture Theaters 2,967.96 40.95 22.22 34.17 25.80 32.42 77.96
2664 CVKD / Cadrenal Therapeutics, Inc. Mga Paghahanda sa Parmasyutiko 26.01 47.25 30.30 36.38 12.86 180.71 77.96
2665 TVGN / Tevogen Bio Holdings Inc.
Tevogen Bio Holdings Inc., based in the United States, operates primarily in the biotechnology sector, focusing on the development of personalized cellular immunotherapies for viral infections and cancers. The company has gained attention for its flagship project, a T cell therapy specifically designed to combat COVID-19 by targeting epitopes associated with the SARS-CoV-2 virus. Tevogen's strategic approach emphasizes the innovation of treatments that are both specific to individual patient immune profiles and scalable for widespread clinical use. This emphasis underscores an intent to address both acute public health needs and long-standing challenges in treating complex viral infections and oncological conditions, underscoring their commitment to advancing healthcare through cutting-edge biotechnological research and development.
176.69 10.50 10.10 10.20 0.91 1,018.18 77.96
2674 ANFIF / Amira Nature Foods Ltd. 0.00 77.93
2676 ELUT / Elutia Inc. Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 97.30 8.40 5.05 6.63 2.28 188.89 77.91
2677 BZAMF / BZAM Ltd.
BZAM Ltd. is a Canadian-based company primarily involved in the cannabis industry. The company focuses on the cultivation, production, and distribution of a wide range of cannabis products, including dry cannabis, oils, and concentrates aimed at both medical and recreational markets. Key projects of BZAM Ltd. include the development of advanced cultivation facilities and innovative product lines designed to align with evolving consumer preferences and regulatory frameworks. The organization is known for leveraging state-of-the-art agricultural technologies to ensure high-quality product output, while also focusing on sustainability practices to minimize its environmental footprint. BZAM Ltd. strategically positions itself to meet both domestic demand within Canada and potential international opportunities as global cannabis legalization progresses.
0.03 77.91
2680 NVAX / Novavax, Inc.
Novavax, Inc., based in the United States, is a biotechnology company primarily engaged in the development and commercialization of vaccines for infectious diseases. Established in 1987, the company operates within the healthcare sector, focusing predominantly on advancing recombinant nanoparticle vaccine technology. Novavax has gained significant attention for its work on NVX-CoV2373, a protein-based vaccine candidate against COVID-19, which has demonstrated high efficacy in clinical trials and received emergency use authorizations in multiple countries. In addition to its COVID-19 vaccine, Novavax is involved in developing other vaccine candidates, including a combined influenza and COVID-19 vaccine to address co-circulating respiratory pathogens. These projects highlight Novavax's commitment to leveraging innovative vaccine technology to meet global public health needs.
Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 1,211.30 26.25 6.06 14.86 7.47 98.70 77.91
2682 RPTX / Repare Therapeutics Inc. Mga Paghahanda sa Parmasyutiko 71.74 5.25 5.05 5.10 1.67 209.09 77.90
2683 NESR / National Energy Services Reunited Corp. Mga Serbisyo sa Larangan ng Langis at Gas, Hindi Nauuri sa Ibang Lugar 902.80 15.75 12.12 13.60 9.36 45.61 77.90
2687 MCHP / Microchip Technology Incorporated
Microchip Technology Incorporated, based in the United States, operates within the semiconductor industry and focuses primarily on microcontroller, mixed-signal, analog, and Flash-IP integrated circuits. The firm catutes to a diversified global client base, across automotive, industrial, aerospace, telecommunications, and consumer electronics sectors. Noteworthy for fostering innovation, Microchip Technology has been at the forefront of developing IoT and microcontroller technologies to enhance connectivity and efficiency. Among its key initiatives, the company emphasizes the development of low-power, high-performance semiconductor solutions that support the growing demands for smart, connected devices. These efforts represent a commitment to technology advancement and sustainability in their field, ensuring their position as a pivotal player in the semiconductor space.
Mga Semiconductor at Mga Kaugnay na Device 35,079.00 94.50 60.60 78.68 65.00 21.05 77.89
2688 CHA / Chagee Holdings Limited - Depositary Receipt (Common Stock) 1,886.50 43.58 31.92 37.03 19.11 93.80 77.89
2690 HSTOQ / Histogen Inc.
Histogen Inc., based in the United States, operates primarily in the biotechnology sector, where its focus lies in the development of regenerative medicine and aesthetics. The company harnesses a proprietary technology that involves cultivating human cells under simulated embryonic conditions to produce products rich in growth factors, which are crucial in stimulating the body's natural process of regeneration and repair. A key project of Histogen has been its innovative pipeline targeting hair growth, oncology, and dermal filler applications. Particularly notable is its hair growth treatment, which has progressed through clinical trial phases and emerged as a highlighted aspect of their research and development efforts. This technology represents a significant stride in therapeutic solutions aimed at tissue and organ disorders.
Mga Paghahanda sa Parmasyutiko 77.89
2692 AGIO / Agios Pharmaceuticals, Inc.
Agios Pharmaceuticals, Inc., based in the United States, operates primarily within the biopharmaceutical sector, focusing on the discovery and development of novel therapeutics in the field of cellular metabolism and rare genetic disorders. A significant aspect of its work emphasizes the development of treatments for cancer and rare diseases, where metabolic pathways play a crucial role. Agios Pharmaceuticals has been particularly noted for its innovative approach towards targeting metabolic enzymes that are altered in cancer cells. This strategy has propelled several projects through clinical trials, aiming to offer solutions for conditions that are poorly served by current treatments. The company has gained attention for collaborating with industry leaders and academic institutions to accelerate drug development and commercialization.
Mga Paghahanda sa Parmasyutiko 2,188.63 59.85 39.39 50.80 37.71 34.70 77.88
2694 DAIO / Data I/O Corporation Mga Instrumento para sa Pagsukat at Pagsubok ng Elektrisidad at Mga Signal na Elektrisidad 29.06 6.30 5.27 5.72 3.10 84.59 77.88
2696 NMPGY / Navios Maritime Holdings Inc. - Preferred Stock 7.81 77.87
2697 EVGN / Evogene Ltd. Mga Kemikal na Pang-agrikultura 9.32 3.68 2.52 3.06 1.25 137.21 77.87
2698 CLPT / ClearPoint Neuro, Inc. Mga Instrumento at Apparatus ng Surgical at Medikal 297.88 31.50 28.28 29.58 10.49 182.25 77.87
2702 TBPMQ / Tetra Bio-Pharma Inc. 0.00 77.85
2703 STTTF / Splitit Payments Ltd 0.00 77.85
2709 SUZ / Suzano S.A. - Depositary Receipt (Common Stock)
Suzano S.A., headquartered in Brazil, is a prominent player in the global pulp and paper industry. It stands as one of the largest producers of pulp in the world and a significant supplier of paper products. The company has been instrumental in championing sustainable practices within the industry, focusing on responsible management of its vast renewable eucalyptus plantations and innovations in bioenergy. Key projects have included major advancements in the production of lignin-rich biomass, which diversifies its product portfolio beyond traditional pulp and paper offerings. Suzano's strategic initiatives also reflect a deep integration of digital technologies and a strong commitment to reducing its environmental footprint, positioning it as a leader in sustainability within the forestry sector.
Papel na MILLS 12,025.39 17.65 11.63 13.95 9.73 43.42 77.82
2710 SEELQ / Seelos Therapeutics, Inc.
Seelos Therapeutics, Inc., based in the United States, operates within the biopharmaceutical industry and focuses on developing therapies for central nervous system disorders and rare diseases. A key element of its project portfolio includes advanced clinical-stage assets targeted at psychiatric and movement disorders, exemplifying its commitment to addressing unmet medical needs. Noteworthy projects include SLS-002 for acute suicidal ideation and behavior in major depressive disorder, and SLS-005 in Huntington's disease, both under expedited regulatory pathways due to their potential significance in therapy. The company’s strategic approach combines repositioning known entities with new mechanistic insights, aiming to streamline the path toward clinical relevance and market entry.
Mga Paghahanda sa Parmasyutiko 77.81
2711 INDI / indie Semiconductor, Inc.
Indie Semiconductor, Inc., based in the United States, operates prominently within the semiconductor industry, focusing on designing and manufacturing semiconductors and software platforms primarily for the automotive sector. The company is a significant player in the development of solutions tailored to enhance vehicle safety, comfort, and connectivity. Key projects include advanced driver-assistance systems (ADAS), connectivity modules, and user interface solutions. Indie Semiconductor is notable for its integrated approach, combining semiconductors with software to provide comprehensive, scalable systems to major auto manufacturers globally. This strategic alignment allows the company to innovate continually while addressing the escalating demand for sophisticated automotive electronics and connectivity solutions.
Mga Semiconductor at Mga Kaugnay na Device 884.05 8.40 4.54 6.05 4.53 33.64 77.81
2714 SECOY / Secoo Holding Limited - Depositary Receipt (Common Stock) Mga Tindahan, Hindi Nauuri sa Ibang Lugar 0.00 77.81
2718 BEEP / Mobile Infrastructure Corporation Real Estate 165.25 7.35 5.05 6.29 3.89 62.53 77.79
2719 BLIN / Bridgeline Digital, Inc.
Bridgeline Digital, Inc., based in the United States, operates primarily in the software industry, focusing on web management software and e-commerce services. The company specializes in providing robust tools for online retail operations, content management, marketing automation, and web analytics, serving to enhance digital engagement and sales effectiveness. Key projects have typically revolved around its flagship product suite, including the Bridgeline Unbound platform, which is designed to provide expansive, cloud-based offerings to support multi-channel marketing strategies and improve online customer experiences. Bridgeline Digital actively serves a diverse range of business sectors, including retail, financial services, healthcare, and others, aiming to drive growth through superior customer engagement metrics and integrated technology solutions.
Naka-prepack na Software 16.35 4.85 3.54 4.14 1.43 191.45 77.79
2721 TNMG / TNL Mediagene 3.68 3.54 3.57 0.42 758.17 77.78
2727 UPS / United Parcel Service, Inc.
United Parcel Service, Inc. (UPS) is a global logistics and package delivery company headquartered in the United States. As a prominent player in the courier service industry, UPS operates in more than 220 countries and territories. Structurally, UPS is known for its brown delivery trucks and uniformed drivers, symbolizing its robust ground delivery network. Key projects and strategic initiatives have included enhancing its global logistics network, integrating advanced technology for package tracking and customer service, and expanding its capacity to handle increased package volumes, especially during peak periods, such as the holiday season. UPS also focuses on sustainability, aiming to reduce emissions and increase the efficiency of its delivery fleet. This commitment includes transitioning to electric vehicles and investing in alternative fuels, which align with broader environmental goals and regulatory requirements.
Mga Serbisyo sa Trucking At Courier, Maliban sa Air 74,061.68 139.65 75.75 107.40 87.44 22.78 77.76
2730 MGNX / MacroGenics, Inc.
MacroGenics, Inc. is a biopharmaceutical company headquartered in the United States. It primarily focuses on discovering and developing innovative monoclonal antibody-based therapeutics for the treatment of cancer and other severe diseases. MacroGenics leverages its proprietary technology platforms, such as DART® and TRIDENT™, to create antibody-based drugs aimed at improving patient outcomes in diseases that currently have limited treatment options. A key project includes the development of margetuximab, an anti-HER2 antibody recently approved by the FDA for breast cancer under the name Margenza. Additionally, MacroGenics has a robust pipeline of candidates in various stages of clinical development targeting a range of oncological and autoimmune diseases. The company demonstrates a strong commitment to advancing science and medicine to meet unmet medical needs.
Mga Paghahanda sa Parmasyutiko 111.87 5.25 2.02 3.47 1.77 94.29 77.75
2737 LBRT / Liberty Energy Inc. Mga Serbisyo sa Larangan ng Langis at Gas, Hindi Nauuri sa Ibang Lugar 1,820.98 19.95 10.10 14.83 11.25 31.84 77.71
2739 VERI / Veritone, Inc. Mga Serbisyo sa Pagproseso ng Computer at Paghahanda at Pagproseso ng Data 145.13 6.30 3.03 4.84 3.05 58.85 77.70
2740 PSHG / Performance Shipping Inc.
Performance Shipping Inc., based in Greece, operates primarily in the global shipping industry, focusing on the transportation of petroleum products. As a tanker company, it manages a fleet composed mainly of Aframax and Panamax tankers, which are pivotal for medium to long-range bulk oil transport. The company consistently engages in strategic fleet expansion and renewal initiatives to maintain its competitive edge and compliance with global shipping standards. Key projects typically include acquisitions of vessels that enhance its operational efficiency and sustainability, reflecting its commitment to environmentally responsible practices. Performance Shipping Inc. also concentrates on optimizing its operational capabilities and cost efficiency to bolster its market position and shareholder value in a dynamic economic landscape.
Deep Sea Dayuhang Transportasyon ng Freight 23.50 6.82 4.04 5.36 1.90 183.33 77.70
2741 ORGO / Organogenesis Holdings Inc.
Organogenesis Holdings Inc., based in the United States, operates within the healthcare sector, focusing primarily on regenerative medicine. The company is a leading developer and manufacturer of products for the advanced wound care, surgical, and sports medicine markets. Its innovative portfolio includes both bioactive and acellular biomaterials that are essential in wound healing, surgical applications, and tissue regeneration. Key projects involve the commercialization of advanced wound care products like Apligraf and Dermagraft, which are used to treat diabetic foot ulcers and venous leg ulcers, highlighting its commitment to addressing critical areas in chronic and acute wound care. Overall, Organogenesis is dedicated to pioneering advancements in healing solutions and regenerative therapies, positioning them as a notable entity in medical technology and biopharmaceuticals.
Mga Paghahanda sa Parmasyutiko 653.30 9.45 7.07 8.16 5.15 58.45 77.69
2742 KPRX / Kiora Pharmaceuticals, Inc.
Kiora Pharmaceuticals, Inc., based in the United States, operates within the biotechnology sector, focusing on developing innovative therapies for diseases with significant unmet medical needs. The company is primarily engaged in advancing a robust pipeline of treatment solutions targeted at ocular diseases. Key projects include a proprietary drug delivery platform designed to enhance the efficacy and safety of existing ophthalmic medications. Additionally, Kiora is involved in the clinical development of various therapeutic candidates aimed at treating conditions such as dry eye disease and persistent corneal epithelial defects. The strategic emphasis of Kiora Pharmaceuticals is on transforming therapeutic modalities to improve outcomes for patients grappling with debilitating eye conditions.
Mga Paghahanda sa Parmasyutiko 9.55 12.60 10.10 11.22 2.78 303.60 77.69
2744 WEJOF / Wejo Group Limited 0.00 77.68
2750 BLND / Blend Labs, Inc. Computer Programming, Pagproseso ng Data, At Iba Pang Serbisyong Kaugnay ng Computer 941.38 7.35 3.54 4.95 3.62 37.04 77.64
2751 RRC / Range Resources Corporation
Range Resources Corporation, based in the United States, is a leading natural gas and natural gas liquids producer with operations primarily focused in the Marcellus Shale in Pennsylvania. The company is dedicated to organic growth strategies, and its key projects center around the exploitation and exploration of scalable, repeatable opportunities within this region. Range Resources is known for its efficient operational strategies and commitment to technological advancements to enhance both productivity and environmental responsibility. Its strategic approach ensures resource maximization and operational excellence, positioning it as a significant player in the natural gas sector of the energy industry. The company's focus on cost-effective operations and sustainable practices underscores its adaptiveness to industry challenges and market dynamics.
Crude Petroleum at Natural Gas 16,346.72 52.50 28.51 43.53 34.27 27.06 77.64
2754 ARTNA / Artesian Resources Corporation Supply ng Tubig 343.08 48.30 46.46 46.92 33.15 41.50 77.62
2756 LION / Lionsgate Studios Corp.
Lions Gate Entertainment Corp., based in the United States and Canada, operates as a diversified global entertainment company. Primarily known for its film production and television programming, Lions Gate has established itself in the entertainment industry with several high-profile projects such as the "Hunger Games" franchise, "Mad Men," and "Orange Is the New Black." The company functions through multiple segments, including Motion Pictures and Television Production, consistently generating content that caters to varying audiences across theatrical, home entertainment, and digital media platforms. This strategic diversification allows Lions Gate to leverage cross-platform opportunities and maintain a strong presence in the competitive entertainment landscape.
Produksyon ng Pelikula, Film, at Video Tape 1,837.69 10.50 7.07 8.86 6.43 37.60 77.62
2759 JUNS / Jupiter Neurosciences, Inc. 51.20 31.50 30.30 30.60 1.47 1,981.63 77.61
2761 MOS / The Mosaic Company
The Mosaic Company, based in the United States, operates primarily within the agricultural sector, producing concentrated phosphate and potash crop nutrients. A key player in global agriculture, Mosaic is instrumental in the development, production, and marketing of these essential nutrients, used widely to support crop growth around the world. The company's strategic projects typically focus on enhancing resource efficiencies and expanding their market reach. Notable initiatives include the development of advanced mining technologies and improvements in the sustainability of supply chains to reduce environmental impact while maintaining profitability. Mosaic's operations are deeply integrated into the agricultural supply chain, ensuring a stable output to meet growing global demand for food production.
Mga Kemikal na Pang-agrikultura 10,597.43 51.45 33.33 41.49 33.40 24.21 77.61
2763 BZAI / Blaize Holdings, Inc. 352.02 10.50 6.06 7.65 3.57 114.89 77.60
2764 DHR / Danaher Corporation
Danaher Corporation, based in the United States, operates as a global science and technology innovator committed to helping customers solve complex challenges and improving quality of life around the world. Primarily functioning within the life sciences, diagnostics, and environmental and applied solutions sectors, the corporation harnesses a strategic portfolio of businesses to foster synergistic progress and sustained growth. Key projects under Danaher’s ambit typically involve advancements in biopharmaceutical development, clinical diagnostics, and water quality analysis. The company strategically focuses on high-growth markets where transformative technologies and customer insights can drive innovation, underpinning its ongoing global leadership in each of these vital sectors, making significant contributions both commercially and societally.
Mga Instrumentong Pang-industriya para sa Pagsukat, Pagpapakita, at Pagkontrol ng mga Variable ng Proseso; at Mga Kaugnay na Produkto 147,346.54 325.50 207.05 247.47 205.82 20.14 77.60
2767 PNTG / The Pennant Group, Inc.
The Pennant Group, Inc., headquartered in the United States, operates predominantly within the healthcare sector, focusing on providing home health, hospice, and senior living services. The company was established through a spin-off from The Ensign Group, Inc. in 2019 to allow more strategic focus and operational flexibility in its service areas. The Pennant Group's model leverages a combination of organic growth and acquisitions to expand its market footprint. Its methodology emphasizes a decentralized approach where individual service centers maintain operational autonomy, which the company believes fosters better local adaptations and efficiency. The firm continues to grow, underlined by strategic acquisitions and enhancements in operational capabilities aimed at improving patient and resident outcomes.
Health Services 835.04 42.00 28.28 34.27 24.01 42.74 77.57
2769 FIP / FTAI Infrastructure Inc. Mga Riles, Line-Haul Operating 553.00 13.65 9.09 11.56 4.80 140.58 77.57
2776 INTA / Intapp, Inc. Naka-prepack na Software 3,738.11 78.75 47.47 62.66 45.99 36.24 77.55
2779 NWSA / News Corporation
News Corporation, based in the United States, operates globally as a diversified media and information services company. It is a prominent player in the publishing and digital real estate services industries, among others. The company's portfolio encompasses a broad range of media, including book publishing, digital and print news, and subscription video services. Key projects and assets include prominent names such as The Wall Street Journal, HarperCollins Publishers, and Realtor.com. News Corporation strives to innovate across its segments, embodying its commitment to information and media dissemination. This strategic diversity positions News Corporation to capitalize on multiple revenue streams while maintaining a significant presence in its primary industry sectors.
Mga Pahayagan: Paglalathala, o Paglalathala at Paglimbag 17,417.12 47.25 26.98 37.54 29.41 27.59 77.55
2784 PRPL / Purple Innovation, Inc. Perabot Rumah Tangga 126.10 5.25 1.62 3.37 1.16 188.93 77.54
2787 KLXE / KLX Energy Services Holdings, Inc.
KLX Energy Services Holdings, Inc., headquartered in the United States, operates primarily within the oilfield services industry, providing a comprehensive range of technical solutions and services to the onshore oil and gas exploration sector. The company specializes in delivering products and services that support the entire lifecycle of an oilfield, from drilling and evaluation through production, maintenance, and enhancement. Key offerings include directional drilling, wellbore placement, and advanced completion solutions, enabling operational efficiency and cost-effectiveness for clients navigating the complex oil and gas market. KLX Energy Services aims to leverage its technical expertise and industry knowledge to foster technological advancements and sustainable practices within the sector.
Mga Serbisyo sa Larangan ng Langis at Gas, Hindi Nauuri sa Ibang Lugar 34.89 5.25 5.05 5.10 1.96 160.87 77.52
2793 AGEN / Agenus Inc.
Agenus Inc. is a biotechnology company based in Lexington, Massachusetts, USA. It specializes in immunology and is primarily focused on the discovery and development of therapies that engage the body's immune system to fight cancer and infections. Agenus emphasizes its portfolio of immuno-oncology products, which include therapeutic antibodies, vaccines, and adjuvants. One of its notable projects is the Prophage series of cancer vaccines, which are currently undergoing various stages of clinical trials targeting different types of malignancies. Additionally, Agenus is developing checkpoint antibodies to augment immune response by inhibiting the mechanisms that allow cancer cells to evade immune detection. Through these projects and collaborations with other pharmaceutical entities, Agenus aims to advance its position in the field of immuno-oncologic therapy development.
Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 125.87 24.15 6.06 11.22 4.18 167.46 77.49
2798 EXEL / Exelixis, Inc.
Exelixis, Inc., based in the United States, operates in the biotechnology industry and is primarily focused on the discovery, development, and commercialization of new medicines for the treatment of cancer. As a leader in the field of oncology, Exelixis has developed and brought to market several therapies, with its flagship product being Cabometyx (cabozantinib), which targets multiple forms of cancer, including renal cell carcinoma and hepatocellular carcinoma. The company's robust pipeline includes a range of compounds at different stages of development, aimed at providing innovative treatments that address unmet medical needs in oncology. Through strategic collaborations and continuous research advancements, Exelixis strives to extend its presence and impact in the cancer treatment landscape.
Mga Biological na Produkto, Maliban sa Diagnostic Substances (Biotech) 10,108.34 63.00 36.36 45.90 37.42 22.69 77.49
2801 STXS / Stereotaxis, Inc. Electromedical at Electrotherapeutic Apparatus 247.68 5.25 4.04 4.59 2.88 59.65 77.48
2802 STRZ / Starz Entertainment Corp. Mga Restaurant, Kainan, at Lugar ng Kainan 213.43 40.95 15.15 23.12 12.77 80.91 77.48
2803 GNPX / Genprex, Inc.
Genprex, Inc., headquartered in the United States, operates within the biotechnology sector, focusing primarily on developing gene therapy-based treatments for cancer and diabetes. The company's flagship product, REQORSA® (quaratusugene ozeplasmid), is designed to administer tumor suppressor genes by encapsulating them into nanoparticles which are then introduced to deficient cells, aiming to combat non-small cell lung cancer. This innovative approach is part of Genprex's broader strategy to integrate its proprietary technology, Oncoprex™ nanoparticle delivery system, to potentially enhance the clinical efficacy of existing cancer drugs. Additionally, Genprex is exploring gene therapies in the treatment of diabetes, signifying its expansion into other serious health conditions beyond oncology.
Mga Paghahanda sa Parmasyutiko 5.44 7.88 7.58 7.65 0.16 4,564.63 77.48
2804 CNTY / Century Casinos, Inc.
Century Casinos, Inc., based in the United States, is a prominent player in the gaming and entertainment industry. Established in 1992, the company operates across various regions with a portfolio of casino properties and resorts. Its concentrations include the operation of casinos filled with slots and gaming tables, hotel services, dining, and entertainment facilities. Key projects involve continual upgrades to existing properties and strategic expansion into new geographic locales. The company's focus on enhancing customer experiences and its strategic international partnerships underpin its growth in both domestic and international markets. Century Casinos' footprint spans North America and Europe, with notable endeavors in cities that are prime for casino tourism and entertainment.
Mga Hotel at Motel 80.48 4.20 3.03 3.82 2.66 42.72 77.47
2805 IZEA / IZEA Worldwide, Inc.
IZEA Worldwide, Inc., based in the United States, is a prominent player in the influencer marketing industry. The company provides a comprehensive platform that facilitates the connection between brands and content creators, fostering partnerships that enable impactful social media campaigns. Key projects and services include IZEAx, an influencer marketing platform designed to streamline the process of content creation and distribution, and BrandGraph, which offers analytics and insights into social content performance and industry trends. IZEA Worldwide, Inc. serves a diverse range of clients, from small businesses to large enterprises, helping them harness the power of influencer relationships in the digital marketing space.
Advertising 63.93 10.50 10.10 10.20 3.78 169.13 77.47
2807 CERT / Certara, Inc. Naka-prepack na Software 1,740.26 18.90 11.62 14.73 10.84 35.98 77.46
2809 CV / CapsoVision, Inc. 9.25 6.30 5.05 5.61 3.75 49.20 77.45
2811 UTI / Universal Technical Institute, Inc. Mga Serbisyong Pang-edukasyon 1,447.13 42.00 36.36 38.18 26.59 43.63 77.44
2812 VNDA / Vanda Pharmaceuticals Inc. Mga Paghahanda sa Parmasyutiko 279.75 21.00 5.05 12.92 4.73 172.86 77.43
2813 RNTX / Rein Therapeutics Inc. Mga Paghahanda sa Parmasyutiko 31.92 7.35 7.07 7.14 1.39 415.52 77.43
2815 ATI / ATI Inc.
As of the information available until early 2023, ATI Inc., based in the United States, operates primarily in the metals industry. The company has earned prominence as a global manufacturer of technically advanced specialty materials and complex components, with its offerings primarily geared towards critical applications in aerospace and defense, oil & gas, medical, automotive, and energy markets. Key projects that underline ATI Inc.'s strategic direction include the expansion of its isothermal forging capabilities and additive manufacturing capacity, aiming to enhance its footprint in aerospace and defense sectors. These initiatives underscore its focus on high-performance materials and innovative technologies, positioning ATI to meet sophisticated client demands and adapt to market dynamics effectively.
Steel Pipe and Tubes 10,687.50 126.00 79.84 99.17 77.54 27.88 77.42
2820 IMDX / Insight Molecular Diagnostics Inc.
OncoCyte Corporation, based in the United States, operates primarily in the biotechnology industry, focusing on the development and commercialization of diagnostic solutions for lung cancer. The company is dedicated to advancing early detection and helping to manage treatment decisions with minimally invasive tests tailored to detect molecular changes and malignancies in patients. A key project includes the commercialization of DetermaRx, a treatment stratification test designed to identify high-risk patients among those who have undergone surgical resection for early-stage lung cancer. Additionally, OncoCyte is developing DetermaIO, a diagnostic test aimed at predicting patient responses to immune checkpoint inhibitor therapies. This innovative line-up places OncoCyte at the forefront of the precision medicine space, addressing critical gaps in cancer diagnosis and treatment.
Mga In Vitro at In Vivo Diagnostic Substances 72.40 8.40 4.04 5.53 2.52 118.38 77.40