ITMN / - Pengajuan SECLaporan Tahunan, Pernyataan Proksi

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SEC Filings
All companies that sell securities in the United States must register with the Securities and Exchange Commission (SEC) and file reports on a regular basis. These reports include company annual reports (10K, 10Q), news updates (8K), investor presentations (found in 8Ks), insider trades (form 4), ownership reports (13D, and 13G), and reports related to the specific securities sold, such as registration statements and prospectus. This page shows recent SEC filings related to
SEC Filings (Chronological Order)
Halaman ini menyediakan daftar lengkap dan kronologis dari Pengajuan SEC, tidak termasuk pengajuan kepemilikan yang kami sediakan di tempat lain.
October 27, 2014 15-12G

ITMN / 15-12G - - FORM 15-12G

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 15 CERTIFICATION AND NOTICE OF TERMINATION OF REGISTRATION UNDER SECTION 12(g) OF THE SECURITIES EXCHANGE ACT OF 1934 OR SUSPENSION OF DUTY TO FILE REPORTS UNDER SECTIONS 13 AND 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934. Commission File Number 000-29801 InterMune, Inc. (Exact name of registrant as specified in its char

October 2, 2014 EX-99.1

INTERMUNE ANNOUNCES EFFECTIVE DATE OF MAKE WHOLE FUNDAMENTAL CHANGE AND OFFER TO PURCHASE TO HOLDERS OF 2.50% SENIOR CONVERTIBLE NOTES DUE 2018

INTERMUNE ANNOUNCES EFFECTIVE DATE OF MAKE WHOLE FUNDAMENTAL CHANGE AND OFFER TO PURCHASE TO HOLDERS OF 2.

October 2, 2014 8-K

Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 2, 2014 INTERMUNE, INC. (Exact name of registrant as specified in its charter) Delaware (State or other jurisdiction of incorporation) 0-29801 (Commission File Number) 94-3296

September 29, 2014 EX-4.5

FOURTH SUPPLEMENTAL INDENTURE

Exhibit 4.5 FOURTH SUPPLEMENTAL INDENTURE This Fourth Supplemental Indenture (“Fourth Supplemental Indenture”) is dated as of September 29, 2014 among InterMune, Inc., a Delaware corporation (the “Issuer”), Roche Holdings, Inc., a Delaware corporation (the “Parent”), and The Bank of New York Mellon Trust Company, N.A., a national banking association, as trustee under the Indenture defined below (t

September 29, 2014 8-K

Changes in Control of Registrant, Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Amendments to Articles of Incorporation or Bylaws; Change in Fiscal Year, Entry into a Material Definitive Agreement, Material Modification to Rights of Security Holders, Notice of Delisting or Failure to Satisfy a Continued Listing Rule or Standard; Transfer of Listing, Financial Statements and Exhibits, Completion of Acquisition or Disposition of Assets, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 26, 2014 INTERMUNE, INC. (Exact Name of Registrant as Specified in its Charter) Delaware 0-29801 94-3296648 (State or Other Jurisdiction (Commission File Number) (IRS Employ

September 29, 2014 S-8 POS

ITMN / S-8 POS - - POST-EFFECTIVE AMENDMENT NO. 1

AS FILED WITH THE SECURITIES AND EXCHANGE COMMISSION ON SEPTEMBER 29, 2014 Registration Statement File No.

September 29, 2014 S-8 POS

ITMN / S-8 POS - - POST-EFFECTIVE AMENDMENT NO. 1

AS FILED WITH THE SECURITIES AND EXCHANGE COMMISSION ON SEPTEMBER 29, 2014 Registration Statement File No.

September 29, 2014 POS AM

ITMN / POS AM - - POST-EFFECTIVE AMENDMENT NO. 1

AS FILED WITH THE SECURITIES AND EXCHANGE COMMISSION ON SEPTEMBER 29, 2014 Registration Statement File No.

September 29, 2014 POS AM

ITMN / POS AM - - POST-EFFECTIVE AMENDMENT NO. 1

AS FILED WITH THE SECURITIES AND EXCHANGE COMMISSION ON SEPTEMBER 29, 2014 Registration Statement File No.

September 29, 2014 POS AM

ITMN / POS AM - - POST-EFFECTIVE AMENDMENT NO. 1

POS AM 1 pos-am.htm POST-EFFECTIVE AMENDMENT NO. 1 AS FILED WITH THE SECURITIES AND EXCHANGE COMMISSION ON SEPTEMBER 29, 2014 Registration Statement File No. 333-139713 UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 Post-Effective Amendment No. 1 to Form S-3 Registration Statement No. 333-139713 UNDER THE SECURITIES ACT OF 1933 INTERMUNE, INC. (Exact name of registrant as

September 29, 2014 POS AM

ITMN / POS AM - - POST-EFFECTIVE AMENDMENT NO. 1

AS FILED WITH THE SECURITIES AND EXCHANGE COMMISSION ON SEPTEMBER 29, 2014 Registration Statement File No.

September 29, 2014 EX-3.2

BYLAWS INTERMUNE, INC. * * * * * ARTICLE 1

Exhibit 3.2 BYLAWS OF INTERMUNE, INC. * * * * * ARTICLE 1 OFFICES Section 1.01. Registered Office. The registered office of the Corporation shall be in the City of Wilmington, County of New Castle, State of Delaware. Section 1.02. Other Offices. The Corporation may also have offices at such other places both within and without the State of Delaware as the Board of Directors may from time to time d

September 29, 2014 S-8 POS

ITMN / S-8 POS - - POST-EFFECTIVE AMENDMENT NO. 1

AS FILED WITH THE SECURITIES AND EXCHANGE COMMISSION ON SEPTEMBER 29, 2014 Registration Statement File No.

September 29, 2014 S-8 POS

ITMN / S-8 POS - - POST-EFFECTIVE AMENDMENT NO. 1

AS FILED WITH THE SECURITIES AND EXCHANGE COMMISSION ON SEPTEMBER 29, 2014 Registration Statement File No.

September 29, 2014 SC 14D9/A

ITMN / SC 14D9/A - - AMENDMENT NO. 7

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14D-9 (Rule 14d-101) (Amendment No. 7) Solicitation/Recommendation Statement Under Section 14(d)(4) of the Securities Exchange Act of 1934 INTERMUNE, INC. (Name of Subject Company) INTERMUNE, INC. (Names of Persons Filing Statement) Common Stock, par value $0.001 per share (Title of Class of Securities) 45884X103 (CUS

September 29, 2014 EX-4.4

THIRD SUPPLEMENTAL INDENTURE

Exhibit 4.4 THIRD SUPPLEMENTAL INDENTURE This Third Supplemental Indenture (“Third Supplemental Indenture”) is dated as of September 29, 2014 among InterMune, Inc., a Delaware corporation (the “Issuer”), Roche Holdings, Inc., a Delaware corporation (the “Parent”), and The Bank of New York Mellon Trust Company, N.A., a national banking association, as trustee under the Indenture defined below (the

September 29, 2014 POS AM

ITMN / POS AM - - POST-EFFECTIVE AMENDMENT NO.1

AS FILED WITH THE SECURITIES AND EXCHANGE COMMISSION ON SEPTEMBER 29, 2014 Registration Statement File No.

September 29, 2014 POS AM

ITMN / POS AM - - POST-EFFECTIVE AMENDMENT NO. 1

AS FILED WITH THE SECURITIES AND EXCHANGE COMMISSION ON SEPTEMBER 29, 2014 Registration Statement File No.

September 29, 2014 S-8 POS

ITMN / S-8 POS - - POST-EFFECTIVE AMENDMENT NO. 1

AS FILED WITH THE SECURITIES AND EXCHANGE COMMISSION ON SEPTEMBER 29, 2014 Registration Statement File No.

September 29, 2014 EX-99.1

Media Release

Exhibit 99.1 Media Release Basel, 29 September 2014 Roche purchases shares in tender offer for InterMune, Inc. Roche (SIX: RO, ROG; OTCQX: RHHBY) and InterMune, Inc. (NASDAQ: ITMN) today announced that Roche’s wholly owned subsidiary Klee Acquisition Corporation has accepted for payment all shares validly tendered pursuant to its tender offer for all outstanding shares of common stock of InterMune

September 29, 2014 EX-3.1

AMENDED AND RESTATED CERTIFICATE OF INCORPORATION INTERMUNE, INC.

Exhibit 3.1 AMENDED AND RESTATED CERTIFICATE OF INCORPORATION OF INTERMUNE, INC. FIRST: The name of the corporation is InterMune, Inc. (the “Corporation”). SECOND: The address of its registered office in the State of Delaware is Corporation Trust Center, 1209 Orange Street, City of Wilmington, County of New Castle, Delaware 19801. The name of its registered agent at such address is The Corporation

September 29, 2014 S-8 POS

ITMN / S-8 POS - - POST-EFFECTIVE AMENDMENT NO. 1

AS FILED WITH THE SECURITIES AND EXCHANGE COMMISSION ON SEPTEMBER 29, 2014 Registration Statement File No.

September 29, 2014 S-8 POS

ITMN / S-8 POS - - POST-EFFECTIVE AMENDMENT NO. 1

AS FILED WITH THE SECURITIES AND EXCHANGE COMMISSION ON SEPTEMBER 29, 2014 Registration Statement File No.

September 29, 2014 S-8 POS

ITMN / S-8 POS - - POST-EFFECTIVE AMENDMENT NO. 1

AS FILED WITH THE SECURITIES AND EXCHANGE COMMISSION ON SEPTEMBER 29, 2014 Registration Statement File No.

September 29, 2014 POS AM

ITMN / POS AM - - POST-EFFECTIVE AMENDMENT NO. 1

AS FILED WITH THE SECURITIES AND EXCHANGE COMMISSION ON SEPTEMBER 29, 2014 Registration Statement File No.

September 29, 2014 POS AM

ITMN / POS AM - - POST-EFFECTIVE AMENDMENT NO. 1

AS FILED WITH THE SECURITIES AND EXCHANGE COMMISSION ON SEPTEMBER 29, 2014 Registration Statement File No.

September 29, 2014 POSASR

ITMN / POSASR - - POST-EFFECTIVE AMENDMENT NO. 1

AS FILED WITH THE SECURITIES AND EXCHANGE COMMISSION ON SEPTEMBER 29, 2014 Registration Statement File No.

September 29, 2014 S-8 POS

ITMN / S-8 POS - - POST-EFFECTIVE AMENDMENT NO. 1

AS FILED WITH THE SECURITIES AND EXCHANGE COMMISSION ON SEPTEMBER 29, 2014 Registration Statement File No.

September 29, 2014 S-8 POS

ITMN / S-8 POS - - POST-EFFECTIVE AMENDMENT NO. 1

AS FILED WITH THE SECURITIES AND EXCHANGE COMMISSION ON SEPTEMBER 29, 2014 Registration Statement File No.

September 29, 2014 S-8 POS

ITMN / S-8 POS - - POST-EFFECTIVE AMENDMENT NO. 1

AS FILED WITH THE SECURITIES AND EXCHANGE COMMISSION ON SEPTEMBER 29, 2014 Registration Statement File No.

September 23, 2014 SC 14D9/A

ITMN / SC 14D9/A - - AMENDMENT NO. 6

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14D-9 (Rule 14d-101) (Amendment No. 6) Solicitation/Recommendation Statement Under Section 14(d)(4) of the Securities Exchange Act of 1934 INTERMUNE, INC. (Name of Subject Company) INTERMUNE, INC. (Names of Persons Filing Statement) Common Stock, par value $0.001 per share (Title of Class of Securities) 45884X103 (CUS

September 22, 2014 SC 14D9/A

ITMN / SC 14D9/A - - AMENDMENT NO. 5

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14D-9 (Rule 14d-101) (Amendment No. 5) Solicitation/Recommendation Statement Under Section 14(d)(4) of the Securities Exchange Act of 1934 INTERMUNE, INC. (Name of Subject Company) INTERMUNE, INC. (Names of Persons Filing Statement) Common Stock, par value $0.001 per share (Title of Class of Securities) 45884X103 (CUS

September 19, 2014 SC 14D9/A

ITMN / SC 14D9/A - - AMENDMENT NO. 4

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14D-9 (Rule 14d-101) (Amendment No. 4) Solicitation/Recommendation Statement Under Section 14(d)(4) of the Securities Exchange Act of 1934 INTERMUNE, INC. (Name of Subject Company) INTERMUNE, INC. (Names of Persons Filing Statement) Common Stock, par value $0.001 per share (Title of Class of Securities) 45884X103 (CUS

September 19, 2014 SC 14D9/A

ITMN / SC 14D9/A - - AMENDMENT NO. 3

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14D-9 (Rule 14d-101) (Amendment No. 3) Solicitation/Recommendation Statement Under Section 14(d)(4) of the Securities Exchange Act of 1934 INTERMUNE, INC. (Name of Subject Company) INTERMUNE, INC. (Names of Persons Filing Statement) Common Stock, par value $0.001 per share (Title of Class of Securities) 45884X103 (CUS

September 12, 2014 SC 14D9/A

ITMN / SC 14D9/A - - AMENDMENT NO. 2

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14D-9 (Rule 14d-101) (Amendment No. 2) Solicitation/Recommendation Statement Under Section 14(d)(4) of the Securities Exchange Act of 1934 INTERMUNE, INC. (Name of Subject Company) INTERMUNE, INC. (Names of Persons Filing Statement) Common Stock, par value $0.001 per share (Title of Class of Securities) 45884X103 (CUS

September 12, 2014 CORRESP

ITMN / CORRESP - -

September 12, 2014 InterMune, Inc. Schedule 14D-9 filed August 29, 2014 SEC File No. 005-60673 Dear Mr. Duchovny: On behalf of our client InterMune, Inc. (“InterMune”), set forth below are the responses of InterMune to the comments of the staff of the Division of Corporation Finance, Office of Mergers and Acquisitions (the “Staff”), of the Securities and Exchange Commission (the “Commission”) in t

September 5, 2014 EX-99.2

INTERMUNE ANNOUNCES ANTICIPATED FUNDAMENTAL CHANGE FOR 5.00% CONVERTIBLE SENIOR NOTES DUE 2015

Prepared by R.R. Donnelley Financial - EX-99.2 Exhibit 99.2 INTERMUNE ANNOUNCES ANTICIPATED FUNDAMENTAL CHANGE FOR 5.00% CONVERTIBLE SENIOR NOTES DUE 2015 BRISBANE, Calif., September 5, 2014 — InterMune, Inc. (Nasdaq: ITMN) today provided the following notice to the indenture trustee and holders of its outstanding 5.00% Convertible Senior Notes Due 2015: Re: Notice of Anticipated Fundamental Chang

September 5, 2014 SC 14D9/A

ITMN / SC 14D9/A - - AMENDMENT NO. 1

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14D-9 (Rule 14d-101) (Amendment No. 1) Solicitation/Recommendation Statement Under Section 14(d)(4) of the Securities Exchange Act of 1934 INTERMUNE, INC. (Name of Subject Company) INTERMUNE, INC. (Names of Persons Filing Statement) Common Stock, par value $0.001 per share (Title of Class of Securities) 45884X103 (CUS

September 5, 2014 EX-99.3

InterMune, Inc. 3280 Bayshore Boulevard Brisbane, CA 94005

Prepared by R.R. Donnelley Financial - EX-99.3 Exhibit 99.3 InterMune, Inc. 3280 Bayshore Boulevard Brisbane, CA 94005 September 5, 2014 To: Holders of InterMune, Inc. 2.50% Convertible Senior Notes due 2017 and The Bank of New York Mellon Trust Company, N.A. 400 South Hope Street, Suite 400 Los Angeles, California 90071 Attention: Corporate Trust Unit, Alex Briffett Re: Notice of Convertibility o

September 5, 2014 EX-99.1

InterMune, Inc. 3280 Bayshore Boulevard Brisbane, CA 94005 To: Holders of InterMune, Inc. 5.00% Convertible Senior Notes due 2015 and The Bank of New York Mellon Trust Company, N.A. 400 South Hope Street, Suite 400 Los Angeles, California 90071 Atten

Prepared by R.R. Donnelley Financial - EX-99.1 Exhibit 99.1 InterMune, Inc. 3280 Bayshore Boulevard Brisbane, CA 94005 To: Holders of InterMune, Inc. 5.00% Convertible Senior Notes due 2015 and The Bank of New York Mellon Trust Company, N.A. 400 South Hope Street, Suite 400 Los Angeles, California 90071 Attention: Corporate Trust Unit, Alex Briffett Re: Notice of Anticipated Fundamental Change Ref

September 5, 2014 8-K

Financial Statements and Exhibits, Other Events

Prepared by R.R. Donnelley Financial - Form 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 5, 2014 INTERMUNE, INC. (Exact name of registrant as specified in its charter) Delaware 0-29801 94-3296648 (State or other ju

August 29, 2014 SC 14D9

ITMN / SC 14D9 - - SC 14D9

SC 14D9 Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.

August 26, 2014 EX-99.2

Special InterMune All Hands Meeting August 25, 2014

Exhibit 99.2 Special InterMune All Hands Meeting August 25, 2014 CAUTIONARY STATEMENT REGARDING FORWARD-LOOKING STATEMENTS SOME OF THE STATEMENTS CONTAINED IN THIS ANNOUNCEMENT ARE FORWARD-LOOKING STATEMENTS, INCLUDING STATEMENTS REGARDING THE EXPECTED CONSUMMATION OF THE ACQUISITION, WHICH INVOLVES A NUMBER OF RISKS AND UNCERTAINTIES, INCLUDING THE SATISFACTION OF CLOSING CONDITIONS FOR THE ACQUI

August 26, 2014 SC14D9C

ITMN / SC14D9C - - SCHEDULE 14D-9

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14D-9 (Rule 14d-101) Solicitation/Recommendation Statement Under Section 14(d)(4) of the Securities Exchange Act of 1934 INTERMUNE, INC. (Name of Subject Company) INTERMUNE, INC. (Names of Persons Filing Statement) Common Stock, par value $0.001 per share (Title of Class of Securities) 45884X103 (CUSIP Number of Class of Securities

August 25, 2014 EX-2.1

AGREEMENT AND PLAN OF MERGER dated as of August 22, 2014, ROCHE HOLDINGS, INC., KLEE ACQUISITION CORPORATION INTERMUNE, INC.

Exhibit 2.1 AGREEMENT AND PLAN OF MERGER dated as of August 22, 2014, among ROCHE HOLDINGS, INC., KLEE ACQUISITION CORPORATION and INTERMUNE, INC. TABLE OF CONTENTS Page ARTICLE I The Offer SECTION 1.01. The Offer 1 SECTION 1.02. Company Actions 4 ARTICLE II The Merger SECTION 2.01. The Merger 5 SECTION 2.02. Merger Closing 5 SECTION 2.03. Effective Time 5 SECTION 2.04. Effects of Merger 5 SECTION

August 25, 2014 8-K

Regulation FD Disclosure, Entry into a Material Definitive Agreement, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 OR 15(d) of The Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 22, 2014 INTERMUNE, INC. (Exact Name of Registrant as Specified in its Charter) Delaware 0-29801 94-3296648 (State or Other Jurisdiction (Commission File Number) (IRS Employer

August 25, 2014 EX-99.1

News Release

EX-99.1 3 ex99-1.htm PRESS RELEASE Exhibit 99.1 News Release Roche and InterMune Reach Definitive Merger Agreement · Roche to acquire InterMune for $ 74.00 per share · InterMune’s lead product pirfenidone for idiopathic pulmonary fibrosis to expand Roche’s respiratory product portfolio Basel, Switzerland, Aug. 24, 2014/PRNewswire/-Roche (SIX: RO, ROG; OTCQX: RHHBY) and InterMune, Inc. (NASDAQ: ITM

August 25, 2014 SC14D9C

ITMN / SC14D9C - - SOLICITATION/RECOMMENDATION STATEMENT

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14D-9 (Rule 14d-101) Solicitation/Recommendation Statement Under Section 14(d)(4) of the Securities Exchange Act of 1934 INTERMUNE, INC. (Name of Subject Company) INTERMUNE, INC. (Names of Persons Filing Statement) Common Stock, par value $0.001 per share (Title of Class of Securities) 45884X103 (CUSIP Number of Class of Securities

August 25, 2014 SC14D9C

ITMN / SC14D9C - -

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14D-9 (Rule 14d-101) Solicitation/Recommendation Statement Under Section 14(d)(4) of the Securities Exchange Act of 1934 INTERMUNE, INC. (Name of Subject Company) INTERMUNE, INC. (Names of Persons Filing Statement) Common Stock, par value $0.001 per share (Title of Class of Securities) 45884X103 (CUSIP Number of Class of Securities

August 7, 2014 10-Q

ITMN / 10-Q - Quarterly Report - 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 Form 10-Q ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2014 OR ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 0-29801 INTERMUNE, INC.

August 6, 2014 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

Prepared by R.R. Donnelley Financial - Form 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 6, 2014 INTERMUNE, INC. (Exact name of registrant as specified in its charter) Delaware 0-29801 94-3296648 (State or other juris

August 6, 2014 EX-99.1

INTERMUNE REPORTS SECOND QUARTER 2014 FINANCIAL RESULTS AND BUSINESS HIGHLIGHTS — Transformational H1 2014 includes presentation of Phase 3 ASCEND data, NDA resubmission and target PDUFA date of Nov. 23 for pirfenidone in U.S. – — Reports Esbriet® re

EX-99.1 2 d771672dex991.htm EX-99.1 Exhibit 99.1 Contact: Jim Goff, InterMune, Inc., 415-466-2228, [email protected] INTERMUNE REPORTS SECOND QUARTER 2014 FINANCIAL RESULTS AND BUSINESS HIGHLIGHTS — Transformational H1 2014 includes presentation of Phase 3 ASCEND data, NDA resubmission and target PDUFA date of Nov. 23 for pirfenidone in U.S. – — Reports Esbriet® revenue of $35.7 million in Q2 20

July 17, 2014 8-K

Other Events

Form 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 17, 2014 INTERMUNE, INC. (Exact name of registrant as specified in its charter) Delaware 0-29801 94-3296648 (State or other jurisdiction of incorporation) (Commission Fi

July 3, 2014 8-K

Regulation FD Disclosure

Form 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 3, 2014 INTERMUNE, INC. (Exact name of registrant as specified in its charter) Delaware 0-29801 94-3296648 (State or other jurisdiction of incorporation) (Commission Fil

July 2, 2014 8-K

Unregistered Sales of Equity Securities

8-K 1 d752148d8k.htm 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 30. 2014 INTERMUNE, INC. (Exact name of registrant as specified in its charter) Delaware 0-29801 94-3296648 (State or other jurisdiction of incorporation

June 25, 2014 8-K

Unregistered Sales of Equity Securities - FORM 8-K

Form 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 19, 2014 INTERMUNE, INC. (Exact name of registrant as specified in its charter) Delaware 0-29801 94-3296648 (State or other jurisdiction of incorporation) (Commission Fi

June 11, 2014 SC 13G/A

ITMN / / PRIMECAP MANAGEMENT CO/CA/ - SC 13G/A Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 OMB APPROVAL OMB Number: 3235-0145 Expires: February 28, 2009 Estimated average burden hours per response. . . . . . . . 10.4 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 4)* InterMune Inc. (Name of Issuer) Common (Title of Class of Securities) 45884X103 (CUSIP Number) May 31, 2014 (Date of Event Which

June 4, 2014 EX-99.1

Corporate Overview

EX-99.1 Corporate Overview June 2014 Exhibit 99.1 Forward-looking Statements 1 This presentation contains forward-looking statements made pursuant to the "safe harbor" provisions of the Private Securities Litigation Reform Act of 1995. Investors are cautioned that, without limitation, statements in this presentation regarding InterMune's plans and expectations, including strategies and plans to ex

June 4, 2014 8-K

Regulation FD Disclosure, Financial Statements and Exhibits - 8-K

8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 3, 2014 INTERMUNE, INC. (Exact name of registrant as specified in its charter) Delaware 0-29801 94-3296648 (State or other jurisdiction of incorporation) (Commission File Num

May 27, 2014 8-K

Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 27, 2014 INTERMUNE, INC. (Exact name of registrant as specified in its charter) Delaware 0-29801 94-3296648 (State or other jurisdiction of incorporation) (Commission File Number)

May 19, 2014 8-K

Regulation FD Disclosure - 8-K

8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 18, 2014 INTERMUNE, INC. (Exact name of registrant as specified in its charter) Delaware 0-29801 94-3296648 (State or other jurisdiction of incorporation) (Commission File Num

May 2, 2014 10-Q

Quarterly Report - 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 Form 10-Q ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2014 OR ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 0-29801 INTERMUNE, INC.

May 1, 2014 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition - 8-K

8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 1, 2014 INTERMUNE, INC. (Exact name of registrant as specified in its charter) Delaware 0-29801 94-3296648 (State or other jurisdiction of incorporation) (Commission File Numb

May 1, 2014 EX-99.1

INTERMUNE REPORTS FIRST QUARTER 2014 FINANCIAL RESULTS, CLINICAL DEVELOPMENT AND BUSINESS HIGHLIGHTS

EX-99.1 Exhibit 99.1 Contact: Jim Goff, InterMune, Inc., 415-466-2228, [email protected] INTERMUNE REPORTS FIRST QUARTER 2014 FINANCIAL RESULTS, CLINICAL DEVELOPMENT AND BUSINESS HIGHLIGHTS BRISBANE, Calif., May 1, 2014 — InterMune, Inc. (NASDAQ: ITMN) today announced results from operations for the first quarter ended March 31, 2014. The company also highlighted recent clinical development and

April 18, 2014 DEF 14A

- DEFINITIVE PROXY STATEMENT

Definitive Proxy Statement UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.

March 19, 2014 8-K

Other Events - FORM 8-K

Form 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 19, 2014 INTERMUNE, INC. (Exact name of registrant as specified in its charter) Delaware 0-29801 94-3296648 (State or other jurisdiction of incorporation) (Commission F

March 14, 2014 EX-1.1

InterMune, Inc. Common Stock, par value $0.001 Underwriting Agreement

EX-1.1 2 d693027dex11.htm EX-1.1 Exhibit 1.1 InterMune, Inc. Common Stock, par value $0.001 Underwriting Agreement March 13, 2014 Goldman, Sachs & Co., J.P. Morgan Securities LLC As Representatives of the several Underwriters named in Schedule I hereto, c/o Goldman, Sachs & Co. 200 West Street New York, New York 10282-2198 c/o J.P. Morgan Securities LLC 383 Madison Avenue New York, New York 10179

March 14, 2014 424B5

CALCULATION OF REGISTRATION FEE Title of Each Class of Securities to be Registered Amount to be Registered Proposed Maximum Offering Price Per Unit Proposed Maximum Aggregate Offering Price Amount of Registration Fee(1) Common Stock, $0.001 par value

424B5 Table of Contents Filed Pursuant to Rule 424(b)(5) Registration Statement No.

March 14, 2014 8-K

Financial Statements and Exhibits, Other Events - FORM 8-K

Form 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 13, 2014 INTERMUNE, INC. (Exact name of registrant as specified in its charter) Delaware 0-29801 94-3296648 (State or other jurisdiction of incorporation) (Commission F

March 12, 2014 EX-99.1

INTERMUNE ANNOUNCES PROPOSED PUBLIC OFFERING OF COMMON STOCK

EX-99.1 Exhibit 99.1 Contact: Jim Goff, InterMune, Inc., 415-466-2228, [email protected] INTERMUNE ANNOUNCES PROPOSED PUBLIC OFFERING OF COMMON STOCK Brisbane, Calif. – March 12, 2014 – InterMune, Inc. (NASDAQ: ITMN) today announced that it plans to offer, subject to market and other conditions, 7,500,000 shares of its common stock in an underwritten public offering. The company expects to grant

March 12, 2014 8-K

Financial Statements and Exhibits, Other Events - 8-K

8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 12, 2014 INTERMUNE, INC. (Exact name of registrant as specified in its charter) Delaware 0-29801 94-3296648 (State or other jurisdiction of incorporation) (Commission File N

March 12, 2014 424B5

Subject to Completion. Dated March 12, 2014. Prospectus Supplement to Prospectus dated September 12, 2011. 7,500,000 Shares InterMune, Inc. Common Stock

424B5 Table of Contents Filed Pursuant to Rule 424(b)(5) Registration Statement No.

March 12, 2014 EX-99.2

RISK FACTORS

EX-99.2 Exhibit 99.2 RISK FACTORS Investing in our common stock involves a high degree of risk. Before deciding whether to invest in our common stock, you should consider carefully the risk factors described below. If any of these risks actually occur, it may materially harm our business, financial condition, operating results or cash flow. As a result, the market price of our common stock could d

February 25, 2014 8-K

Regulation FD Disclosure, Financial Statements and Exhibits, Other Events - 8-K

8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 25, 2014 INTERMUNE, INC. (Exact name of registrant as specified in its charter) Delaware 0-29801 94-3296648 (State or other jurisdiction of incorporation) (Commission Fil

February 25, 2014 EX-99.1

ASCEND Top-Line Results

EX-99.1 ASCEND Top-Line Results February 25, 2014 Exhibit 99.1 Forward-looking Statements This presentation contains forward-looking statements made pursuant to the "safe harbor" provisions of the Private Securities Litigation Reform Act of 1995. Investors are cautioned that, without limitation, statements in this presentation regarding InterMune's plans and expectations; the estimated patient pop

February 24, 2014 10-K

Annual Report - FORM 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 Form 10-K ANNUAL REPORT PURSUANT TO SECTIONS 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 þ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2013 or ¨ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission file number 0-29801 INTERMUNE, INC.

February 24, 2014 EX-10

July 5, 2013

EX-10 2 itmn-ex1020131231592.htm EX-10.16 Exhibit 10.16 July 5, 2013 Andrew Powell **** ****** **** *** **** ** ***** Re: Employment with lnterMune, Inc. Dear Andrew: On behalf of lnterMune, Inc., I am pleased to extend to you this official offer of employment with lnterMune as Executive Vice President, General Counsel & Corporate Secretary, reporting to Daniel Welch, Chairman of the Board, CEO &

February 24, 2014 EX-21

SUBSIDIARIES OF INTERMUNE, INC.

Exhibit 21.1 SUBSIDIARIES OF INTERMUNE, INC. Name of Subsidiary Country of Incorporation InterMune Canada, Inc. Canada InterMune Holdings, Ltd. United Kingdom InterMune UK Ltd. United Kingdom InterMune UK & I Ltd. United Kingdom InterMune Bristol Ltd. United Kingdom InterMune International AG Switzerland InterMune Schweiz GmbH Switzerland InterMune S.r.l. Italy InterMune Deutschland GmbH Germany I

February 14, 2014 SC 13G/A

ITMN / / Visium Asset Management, LP - SC 13G/A Passive Investment

SC 13G/A SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 1)* Intermune, Inc. (Name of Issuer) COMMON STOCK, $0.001 PER SHARE (Title of Class of Securities) 45884X103 (CUSIP Number) December 31, 2013 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which

February 14, 2014 SC 13G/A

ITMN / / Flynn James E Passive Investment

SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 SCHEDULE 13G (Rule 13d-102) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO RULES 13d-1(b)(c), AND (d) AND AMENDMENTS THERETO FILED PURSUANT TO RULE 13d-2(b) (Amendment No.

February 14, 2014 SC 13G/A

ITMN / / QVT Financial LP - SCHEDULE 13G AMENDMENT NO. 5 Passive Investment

SC 13G/A 1 d675484dsc13ga.htm SCHEDULE 13G AMENDMENT NO. 5 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 5)* InterMune, Inc. (Name of Issuer) Common Stock, $0.001 par value per share (Title of Class of Securities) 45884X103 (CUSIP Number) December 31, 2013 (Date of Event Which Requires Filing of this St

February 14, 2014 SC 13G/A

ITMN / / PRIMECAP MANAGEMENT CO/CA/ - SC 13G/A Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 OMB APPROVAL OMB Number: 3235-0145 Expires: February 28, 2009 Estimated average burden hours per response. . . . . . . . 10.4 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 3)* InterMune Inc. (Name of Issuer) Common (Title of Class of Securities) 45884X103 (CUSIP Number) December 31, 2013 (Date of Event

February 13, 2014 SC 13G

ITMN / / ORBIMED ADVISORS LLC - SCHEDULE 13G FILING Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Intermune, Inc.

February 11, 2014 SC 13G/A

ITMN / / SECTORAL ASSET MANAGEMENT INC - SC 13G/A Passive Investment

SC 13G/A 1 a14-50133sc13ga.htm SC 13G/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G/A Under the Securities Exchange Act of 1934 (Amendment No. 13)* INTERMUNE INC (Name of Issuer) COMMON STOCK (Title of Class of Securities) 45884X103 (CUSIP Number) DECEMBER 31, 2013 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designat

February 11, 2014 SC 13G/A

ITMN / / VANGUARD GROUP INC Passive Investment

intermune.htm - Generated by SEC Publisher for SEC Filing SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Schedule 13G Under the Securities Exchange Act of 1934 (Amendment No.: 1 )* Name of issuer: InterMune Inc Title of Class of Securities: Common Stock CUSIP Number: 45884X103 Date of Event Which Requires Filing of this Statement: December 31, 2013 Check the appropriate box to designate

February 11, 2014 SC 13G/A

ITMN / / PRICE T ROWE ASSOCIATES INC /MD/ - ITMN AS OF 12/31/2013 Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 3)* INTERMUNE INC (Name of Issuer) COMMON STOCK (Title of Class of Securities) 45884X103 (CUSIP Number) December 31, 2013 (Date of Event which Requires Filing of Statement) Check the appropriate box to designate the Rule pursuant to which this Schedule is fi

January 13, 2014 8-K

Regulation FD Disclosure, Financial Statements and Exhibits, Results of Operations and Financial Condition - 8-K

8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 9, 2014 INTERMUNE, INC. (Exact name of registrant as specified in its charter) Delaware 0-29801 94-3296648 (State or other jurisdiction of incorporation) (Commission File

January 13, 2014 EX-99.2

J.P. Morgan 2014

EX-99.2 J.P. Morgan 2014 Healthcare Conference January 13, 2014 Exhibit 99.2 Forward-looking Statements This presentation contains forward-looking statements made pursuant to the "safe harbor" provisions of the Private Securities Litigation Reform Act of 1995. Investors are cautioned that, without limitation, statements in this presentation regarding InterMune's plans and expectations; anticipated

January 13, 2014 EX-99.1

INTERMUNE REPORTS PRELIMINARY FOURTH QUARTER 2013 ESBRIET® (PIRFENIDONE) REVENUE AND RECENT BUSINESS HIGHLIGHTS – Q4’13 revenue of $25.6 million represents ninth consecutive quarter of Esbriet growth – – Last patient to complete treatment this month

EX-99.1 Exhibit 99.1 Contact: Jim Goff, InterMune, Inc., 415-466-2228, [email protected] INTERMUNE REPORTS PRELIMINARY FOURTH QUARTER 2013 ESBRIET® (PIRFENIDONE) REVENUE AND RECENT BUSINESS HIGHLIGHTS – Q4’13 revenue of $25.6 million represents ninth consecutive quarter of Esbriet growth – – Last patient to complete treatment this month in Phase 3 ASCEND trial – – Strong progress on antifibrotic

December 2, 2013 8-K

Other Events - FORM 8-K

Form 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 29, 2013 INTERMUNE, INC. (Exact name of registrant as specified in its charter) Delaware 0-29801 94-3296648 (State or other jurisdiction of incorporation) (Commissio

November 6, 2013 EX-1.1

InterMune, Inc. Common Stock, par value $0.001 Underwriting Agreement

EX-1.1 Exhibit 1.1 InterMune, Inc. Common Stock, par value $0.001 Underwriting Agreement November 5, 2013 Goldman, Sachs & Co., J.P. Morgan Securities LLC As Representatives of the several Underwriters named in Schedule I hereto, c/o Goldman, Sachs & Co. 200 West Street New York, New York 10282-2198 c/o J.P. Morgan Securities LLC 383 Madison Avenue New York, New York 10179 Ladies and Gentlemen: In

November 6, 2013 424B5

Prospectus Supplement to Prospectus dated July 18, 2013. 6,500,000 Shares InterMune, Inc. Common Stock

424B5 Table of Contents Filed pursuant to Rule 424(b)(5) Registration Statement No.

November 6, 2013 8-K

Financial Statements and Exhibits, Other Events - FORM 8-K

Form 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 5, 2013 INTERMUNE, INC. (Exact name of registrant as specified in its charter) Delaware 0-29801 94-3296648 (State or other jurisdiction of incorporation) (Commission

November 4, 2013 424B5

Subject to Completion. Dated November 4, 2013. Prospectus Supplement to Prospectus dated July 18, 2013. 6,500,000 Shares InterMune, Inc. Common Stock

424B5 Table of Contents The information in this preliminary prospectus supplement and the accompanying prospectus is not complete and may be changed.

November 1, 2013 10-Q

Quarterly Report - FORM 10-Q

Table of Contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 Form 10-Q þ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2013 OR ¨ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number: 0-29801 INTERMUNE, INC.

November 1, 2013 EX-10.1

SEPARATION AND TRANSITION AGREEMENT AND GENERAL RELEASE

EX-10.1 Exhibit 10.1 SEPARATION AND TRANSITION AGREEMENT AND GENERAL RELEASE This Separation and Transition Agreement and General Release (the “Agreement”) is made by and between Robin Steele (“Executive”) and InterMune, Inc. (the “Company”), effective as of the date Executive signs this Agreement (the “Effective Date”). A. Executive is employed as Senior Vice President of Legal Affairs, General C

October 30, 2013 EX-99.1

INTERMUNE REPORTS THIRD QUARTER 2013 FINANCIAL RESULTS AND BUSINESS HIGHLIGHTS — Reports 8th Consecutive Quarter of Esbriet Revenue Growth —

EX-99.1 Exhibit 99.1 Contact: Jim Goff, InterMune, Inc., 415-466-2228, [email protected] INTERMUNE REPORTS THIRD QUARTER 2013 FINANCIAL RESULTS AND BUSINESS HIGHLIGHTS — Reports 8th Consecutive Quarter of Esbriet Revenue Growth — BRISBANE, Calif., October 30, 2013 — InterMune, Inc. (NASDAQ: ITMN) today announced results from operations for the third quarter and nine months ended September 30, 20

October 30, 2013 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition - 8-K

8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 30, 2013 INTERMUNE, INC. (Exact name of registrant as specified in its charter) Delaware 0-29801 94-3296648 (State or other jurisdiction of incorporation) (Commission File

August 23, 2013 8-K

Amendments to Articles of Incorporation or Bylaws; Change in Fiscal Year, Financial Statements and Exhibits - FORM 8-K

Form 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 19, 2013 INTERMUNE, INC. (Exact name of registrant as specified in its charter) Delaware 0-29801 94-3296648 (State or other jurisdiction of incorporation) (Commission

August 23, 2013 EX-3.1

AMENDMENT TO AMENDED AND RESTATED BYLAWS INTERMUNE, INC. (A DELAWARE CORPORATION) August 19, 2013

EX-3.1 Exhibit 3.1 AMENDMENT TO AMENDED AND RESTATED BYLAWS OF INTERMUNE, INC. (A DELAWARE CORPORATION) August 19, 2013 Pursuant to the resolutions duly adopted by the Board of Directors of InterMune, Inc., a Delaware corporation (the “Company”), effective August 19, 2013, the Amended and Restated Bylaws of the Company, effective as of March 22, 2010 (the “Bylaws”), are amended as follows. A new A

July 24, 2013 EX-99.1

INTERMUNE REPORTS SECOND QUARTER 2013 FINANCIAL RESULTS AND BUSINESS HIGHLIGHTS — Reports 7th Consecutive Quarter of Esbriet Revenue Growth —

EX-99.1 Exhibit 99.1 Contact: Jim Goff, InterMune, Inc., 415-466-2228, [email protected] INTERMUNE REPORTS SECOND QUARTER 2013 FINANCIAL RESULTS AND BUSINESS HIGHLIGHTS — Reports 7th Consecutive Quarter of Esbriet Revenue Growth — BRISBANE, Calif., July 24, 2013 — InterMune, Inc. (NASDAQ: ITMN) today announced results from operations for the second quarter ended June 30, 2013, and recent busines

July 24, 2013 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 24, 2013 INTERMUNE, INC. (Exact name of registrant as specified in its charter) Delaware 0-29801 94-3296648 (State or other jurisdiction of incorporation) (Commission File Number

July 18, 2013 CORRESP

-

CORRESPONDENCE INTERMUNE, INC. 3280 BAYSHORE BOULEVARD BRISBANE, CALIFORNIA 94005 July 18, 2013 VIA EDGAR Securities and Exchange Commission Division of Corporation Finance 100 F Street, N.E. Washington, DC 20549 Attention: Jeffrey P. Riedler, Assistant Director Johnny Gharib Re: InterMune, Inc. Registration Statement on Form S-3 (Registration No. 333-189467) Ladies and Gentlemen: In accordance wi

July 10, 2013 SC 13G/A

ITMN / / PRICE T ROWE ASSOCIATES INC /MD/ - ITMN AS OF 06/30/2013 Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 2)* INTERMUNE INC (Name of Issuer) COMMON STOCK (Title of Class of Securities) 45884X103 (CUSIP Number) June 30, 2013 (Date of Event which Requires Filing of Statement) Check the appropriate box to designate the Rule pursuant to which this Schedule is filed:

June 19, 2013 EX-25.1

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM T-1 STATEMENT OF ELIGIBILITY UNDER THE TRUST INDENTURE ACT OF 1939 OF A CORPORATION DESIGNATED TO ACT AS TRUSTEE

EX-25.1 Exhibit 25.1 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM T-1 STATEMENT OF ELIGIBILITY UNDER THE TRUST INDENTURE ACT OF 1939 OF A CORPORATION DESIGNATED TO ACT AS TRUSTEE ¨ CHECK IF AN APPLICATION TO DETERMINE ELIGIBILITY OF A TRUSTEE PURSUANT TO SECTION 305(b)(2) THE BANK OF NEW YORK MELLON TRUST COMPANY, N.A. (Exact name of trustee as specified in its char

June 19, 2013 S-3

- FORM S-3

Form S-3 Table of Contents As filed with the Securities and Exchange Commission on June 19, 2013 Registration No.

June 19, 2013 EX-12.1

COMPUTATION OF RATIO OF EARNINGS TO FIXED CHARGES Three months ended March 31, Year ended December 31, 2013 2012 2011 2010(A) 2009 2008 (In thousands) Earnings: Income (loss) from continuing operations and before income taxes ($ 49,706 ) ($ 203,322 )

EX-12.1 Exhibit 12.1 COMPUTATION OF RATIO OF EARNINGS TO FIXED CHARGES Three months ended March 31, Year ended December 31, 2013 2012 2011 2010(A) 2009 2008 (In thousands) Earnings: Income (loss) from continuing operations and before income taxes ($ 49,706 ) ($ 203,322 ) ($ 166,945 ) $ 109,228 ($ 131,875 ) ($ 126,993 ) Add: Fixed Charges 3,582 9,281 6,998 9,367 11,097 14,124 Earnings, as defined (

June 14, 2013 S-8

- S-8

S-8 As filed with the Securities and Exchange Commission on June 14, 2013 Registration No.

June 14, 2013 EX-99.2

InterMune, Inc. Amended and Restated 2000 Equity Incentive Plan Notice of Grant of Stock Option and Stock Option Terms and Conditions InterMune, Inc. 3280 Bayshore Boulevard Brisbane, CA 94005 (415) 466-2200 «First» «Middle» «Last» Social Security Nu

EX-99.2 Exhibit 99.2 InterMune, Inc. Amended and Restated 2000 Equity Incentive Plan Notice of Grant of Stock Option and Stock Option Terms and Conditions InterMune, Inc. 3280 Bayshore Boulevard Brisbane, CA 94005 (415) 466-2200 «First» «Middle» «Last» Social Security Number: «SSNo» «Address» Grant Number: «GrantNo» «City», «State» «Zip» Date of Grant: Vesting Commencement Date: Exercise Price per

June 14, 2013 8-K

Other Events - FORM 8-K

Form 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 14, 2013 INTERMUNE, INC. (Exact name of registrant as specified in its charter) Delaware 0-29801 94-3296648 (State or other jurisdiction of incorporation) (Commission Fi

June 5, 2013 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Amendments to Articles of Incorporation or Bylaws; Change in Fiscal Year, Financial Statements and Exhibits, Submission of Matters to a Vote of Security Holders - FORM 8-K

Form 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 30, 2013 INTERMUNE, INC. (Exact name of registrant as specified in its charter) Delaware 0-29801 94-3296648 (State or other jurisdiction of incorporation) (Commission Fil

June 5, 2013 EX-10.1

INTERMUNE, INC. AMENDED AND RESTATED 2000 EQUITY INCENTIVE PLAN Adopted January 31, 2000 Approved by Stockholders: March 20, 2000 Amended on: April 4, 2002 and June 19, 2002 Approved by Stockholders: June 19, 2002 Amended and Restated on: April 2, 20

EX-10.1 Exhibit 10.1 INTERMUNE, INC. AMENDED AND RESTATED 2000 EQUITY INCENTIVE PLAN Adopted January 31, 2000 Approved by Stockholders: March 20, 2000 Amended on: April 4, 2002 and June 19, 2002 Approved by Stockholders: June 19, 2002 Amended and Restated on: April 2, 2004 Approved by Stockholders: May 27, 2004 Amended and Restated on: March 7, 2007 Amended on: April 27, 2007 Approved by Stockhold

June 5, 2013 EX-10.2

INTERMUNE, INC. RESTRICTED STOCK UNIT DEFERRAL ELECTION AGREEMENT

EX-10.2 Exhibit 10.2 INTERMUNE, INC. RESTRICTED STOCK UNIT DEFERRAL ELECTION AGREEMENT Please complete this Election Agreement and return a signed copy to , of InterMune, Inc. (the “Company”) no later than the thirtieth (30th) day following the Date of Grant specified in your Notice of Grant of Stock Bonus Award (the “Notice of Grant”). Defined terms not explicitly defined in this Election Agreeme

June 5, 2013 EX-3.1

CERTIFICATE OF AMENDMENT OF AMENDED AND RESTATED CERTIFICATE OF INCORPORATION OF INTERMUNE, INC.

EX-3.1 Exhibit 3.1 CERTIFICATE OF AMENDMENT OF AMENDED AND RESTATED CERTIFICATE OF INCORPORATION OF INTERMUNE, INC. INTERMUNE, INC., a corporation organized and existing under and by virtue of the General Corporation Law of the State of Delaware (the “Corporation”), does hereby certify: FIRST: The name of the Corporation is InterMune, Inc. SECOND: The date on which the Certificate of Incorporation

June 5, 2013 EX-10.3

InterMune, Inc. Amended and Restated 2000 Equity Incentive Plan Notice of Grant of Stock Bonus Award – Restricted Stock Units

EX-10.3 Exhibit 10.3 InterMune, Inc. Amended and Restated 2000 Equity Incentive Plan Notice of Grant of Stock Bonus Award – Restricted Stock Units InterMune, Inc. 3280 Bayshore Boulevard Brisbane, CA 94005 (415) 466-2200 «First» «Middle» «Last» «Address» Award Number: «GrantNo» «City», «County» «Postcode» Date of Grant: «DateofGrant» [Vesting Commencement Date: «VestingStartDate»] [Total [Target]

April 24, 2013 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition - CURRENT REPORT ON FORM 8-K

Current Report on Form 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.

April 24, 2013 EX-99.1

INTERMUNE REPORTS FIRST QUARTER 2013 FINANCIAL RESULTS AND BUSINESS HIGHLIGHTS

EX-99.1 Exhibit 99.1 Contact: Jim Goff, InterMune, Inc., 415-466-2228, [email protected] INTERMUNE REPORTS FIRST QUARTER 2013 FINANCIAL RESULTS AND BUSINESS HIGHLIGHTS BRISBANE, Calif., April 24, 2013 – InterMune, Inc. (NASDAQ: ITMN) today announced results from operations for the first quarter ended March 31, 2013 and recent business highlights. InterMune reported Esbriet® (pirfenidone) revenue

April 22, 2013 SC 13G

ITMN / / Visium Asset Management, LP - SCHEDULE 13G Passive Investment

Schedule 13G SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 Intermune, Inc. (Name of Issuer) COMMON STOCK, $0.001 PER SHARE (Title of Class of Securities) 45884X103 (CUSIP Number) April 10, 2013 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which this Schedule is

April 16, 2013 DEF 14A

- DEF 14A

DEF 14A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No. ) Filed by the Registrant x Filed by a Party other than the Registrant ¨ Check the appropriate box: ¨ Preliminary Proxy Statement ¨

April 2, 2013 PRE 14A

- PRELIMINARY PROXY STATEMENT

Preliminary Proxy Statement UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.

March 21, 2013 8-K

Other Events - FORM 8-K

Form 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 20, 2013 INTERMUNE, INC. (Exact name of registrant as specified in its charter) Delaware (State or other jurisdiction of incorporation) 0-29801 (Commission File Number)

March 4, 2013 8-K

Other Events - FORM 8-K

Form 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 1, 2013 INTERMUNE, INC. (Exact name of registrant as specified in its charter) Delaware 0-29801 94-3296648 (State or other jurisdiction of incorporation) (Commission Fi

March 1, 2013 8-K

Non-Reliance on Previously Issued Financial Statements or a Related Audit Report or Completed Interim Review - FORM 8-K

Form 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 25, 2013 INTERMUNE, INC. (Exact name of registrant as specified in its charter) Delaware 0-29801 94-3296648 (State or other jurisdiction of incorporation) (Commissio

February 21, 2013 EX-99.1

INTERMUNE REPORTS FOURTH QUARTER AND FULL YEAR 2012 FINANCIAL RESULTS AND BUSINESS HIGHLIGHTS

EX-99.1 Exhibit 99.1 Contact: Jim Goff, InterMune, Inc., 415-466-2228, [email protected] INTERMUNE REPORTS FOURTH QUARTER AND FULL YEAR 2012 FINANCIAL RESULTS AND BUSINESS HIGHLIGHTS BRISBANE, Calif., February 21, 2013 - InterMune, Inc. (NASDAQ: ITMN) today announced results from operations for the fourth quarter and full year ended December 31, 2012. InterMune reported Esbriet® (pirfenidone) ne

February 21, 2013 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 21, 2013 INTERMUNE, INC. (Exact name of registrant as specified in its charter) Delaware (State or other jurisdiction of incorporation) 0-29801 94-3296648 (Commission File Nu

February 19, 2013 8-K

Entry into a Material Definitive Agreement - FORM 8-K

Form 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 12, 2013 INTERMUNE, INC. (Exact name of registrant as specified in its charter) Delaware 0-29801 94-3296648 (State or other jurisdiction of incorporation) (Commissio

February 14, 2013 SC 13G/A

ITMN / / COLUMBIA WANGER ASSET MANAGEMENT LLC - SCHEDULE 13G AMENDMENT NO.1 Passive Investment

Schedule 13G Amendment No.1 SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G UNDER THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No. 1)* INTERMUNE INC (Name of Issuer) COMMON STOCK (Title of Class of Securities) 45884X103 (CUSIP Number) December 31, 2012 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the Rule pursuant to which

February 14, 2013 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits

Form 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 14, 2013 INTERMUNE, INC. (Exact name of registrant as specified in its charter) Delaware 0-29801 94-3296648 (State or other jurisdiction of incorporation) (Commissio

February 14, 2013 EX-1

POWER OF ATTORNEY FOR CERTAIN REGULATORY FILINGS INCLUDING CERTAIN FILINGS UNDER THE SECURITIES EXCHANGE ACT OF 1934 AND THE INVESTMENT ADVISERS ACT OF 1940

Exhibit 1 POWER OF ATTORNEY FOR CERTAIN REGULATORY FILINGS INCLUDING CERTAIN FILINGS UNDER THE SECURITIES EXCHANGE ACT OF 1934 AND THE INVESTMENT ADVISERS ACT OF 1940 I, David E.

February 14, 2013 SC 13G/A

ITMN / / Flynn James E Passive Investment

SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 SCHEDULE 13G (Rule 13d-102) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO RULES 13d-1(b)(c), AND (d) AND AMENDMENTS THERETO FILED PURSUANT TO RULE 13d-2(b) (Amendment No.

February 14, 2013 SC 13G/A

ITMN / / BANK OF AMERICA CORP /DE/ - INTERMUNE INC 13G/A1 Passive Investment

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G UNDER THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No. 1)* INTERMUNE INC (Name of Issuer) Common Stock (Title of Class of Securities) 45884X103 (CUSIP Number) December 31, 2012 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the Rule pursuant to which this Schedule is filed: [X]

February 14, 2013 SC 13G/A

ITMN / / D. E. Shaw Valence Portfolios, L.L.C. - AMENDMENT TO SCHEDULE 13G Passive Investment

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G (Amendment No. 2) Under the Securities Exchange Act of 1934 InterMune, Inc. (Name of Issuer) Common Stock, $0.001 par value (Title of Class of Securities) 45884X103 (CUSIP Number) December 31, 2012 (Date of Event Which Requires Filing of this Statement) Check the following box to designate the rule pursuant to which the Schedul

February 14, 2013 SC 13G/A

ITMN / / SECTORAL ASSET MANAGEMENT INC - SC 13G/A Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 12)* INTERMUNE INC (Name of Issuer) COMMON STOCK (Title of Class of Securities) 45884X103 (CUSIP Number) DECEMBER 31, 2012 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which this Schedule

February 14, 2013 SC 13G/A

ITMN / / QVT Financial LP - SC 13G/A Passive Investment

SC 13G/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 4)* InterMune, Inc. (Name of Issuer) Common Stock, $0.001 par value per share (Title of Class of Securities) 45884X103 (CUSIP Number) December 31, 2012 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate th

February 14, 2013 EX-99.1

SEAN P. NOLAN JOINS INTERMUNE AS EXECUTIVE VICE PRESIDENT AND CHIEF BUSINESS OFFICER

EX-99.1 Exhibit 99.1 Contacts: Jim Goff, InterMune, Inc., 415-466-2228, [email protected] SEAN P. NOLAN JOINS INTERMUNE AS EXECUTIVE VICE PRESIDENT AND CHIEF BUSINESS OFFICER BRISBANE, Calif., February 14, 2013—InterMune, Inc. (NASDAQ: ITMN) today announced that Sean P. Nolan has joined InterMune as Executive Vice President and Chief Business Officer. In this newly created position, Mr. Nolan wi

February 13, 2013 SC 13G

ITMN / / VANGUARD GROUP INC Passive Investment

intermuneinc.htm - Generated by SEC Publisher for SEC Filing SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Schedule 13G Under the Securities Exchange Act of 1934 (Amendment No.: 0 )* Name of issuer: InterMune Inc Title of Class of Securities: Common Stock CUSIP Number: 45884X103 Date of Event Which Requires Filing of this Statement: December 31, 2012 Check the appropriate box to design

February 7, 2013 SC 13G/A

ITMN / / PRICE T ROWE ASSOCIATES INC /MD/ - ITMN AS OF 12/31/2012 Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 1)* INTERMUNE INC (Name of Issuer) COMMON STOCK (Title of Class of Securities) 45884X103 (CUSIP Number) December 31, 2012 (Date of Event which Requires Filing of Statement) Check the appropriate box to designate the Rule pursuant to which this Schedule is fi

February 5, 2013 SC 13G/A

ITMN / / PRIMECAP MANAGEMENT CO/CA/ - SC 13G/A Passive Investment

OMB APPROVAL UNITED STATES OMB Number: 3235-0145 SECURITIES AND EXCHANGE COMMISSION Expires: February 28, 2009 Washington, D.

February 4, 2013 SC 13G/A

ITMN / / FRANKLIN RESOURCES INC Passive Investment

CUSIP NO. 45884X103 13G Page 1 of 13 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 1)* INTERMUNE, INC. (Name of Issuer) Common Stock, $0.001 par value (Title of Class of Securities) 45884X103 (CUSIP Number) December 31, 2012 (Date of Event Which Requires Filing of this Statement) Check the appropriate b

February 1, 2013 SC 13G

ITMN / / BAKER BROS. ADVISORS LP - SC 13G Passive Investment

SCHEDULE 13G SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 Under the Securities Exchange Act of 1934 (Amendment No.

January 22, 2013 EX-1.2

InterMune, Inc. 2.50% Convertible Senior Notes due 2017 Underwriting Agreement

Underwriting Agreement Exhibit 1.2 InterMune, Inc. 2.50% Convertible Senior Notes due 2017 Underwriting Agreement January 15, 2013 Goldman, Sachs & Co., J.P. Morgan Securities LLC As Representatives of the several Underwriters named in Schedule I hereto, c/o Goldman, Sachs & Co. 200 West Street New York, New York 10282-2198 c/o J.P. Morgan Securities LLC 383 Madison Avenue New York, New York 10179

January 22, 2013 EX-1.1

InterMune, Inc. Common Stock, par value $0.001 Underwriting Agreement

Exhibit 1.1 InterMune, Inc. Common Stock, par value $0.001 Underwriting Agreement January 15, 2013 Goldman, Sachs & Co., J.P. Morgan Securities LLC As Representatives of the several Underwriters named in Schedule I hereto, c/o Goldman, Sachs & Co. 200 West Street New York, New York 10282-2198 c/o J.P. Morgan Securities LLC 383 Madison Avenue New York, New York 10179 Ladies and Gentlemen: InterMune

January 22, 2013 EX-4.2

INTERMUNE, INC. as Issuer THE BANK OF NEW YORK MELLON TRUST COMPANY, N.A. as Trustee Second Supplemental Indenture Dated as of January 22, 2013 Indenture dated as of September 19, 2011 2.50% Convertible Senior Notes due 2017 TABLE OF CONTENTS PAGE AR

Second Supplemental Indenture Exhibit 4.2 EXECUTION VERSION INTERMUNE, INC. as Issuer AND THE BANK OF NEW YORK MELLON TRUST COMPANY, N.A. as Trustee Second Supplemental Indenture Dated as of January 22, 2013 to Indenture dated as of September 19, 2011 2.50% Convertible Senior Notes due 2017 TABLE OF CONTENTS PAGE ARTICLE 1 CERTAIN DEFINITIONS AND PROVISIONS OF GENERAL APPLICATION Section 1.01 . De

January 22, 2013 8-K

Entry into a Material Definitive Agreement, Financial Statements and Exhibits, Creation of a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement of a Registrant, Other Events - FORM 8-K

Form 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 15, 2013 INTERMUNE, INC. (Exact name of registrant as specified in its charter) Delaware 0-29801 94-3296648 (State or other jurisdiction of incorporation) (Commission

January 16, 2013 424B5

Prospectus Supplement to Prospectus dated December 28, 2012. 13,500,000 Shares InterMune, Inc. Common Stock

Filed Pursuant to Rule 424(b)(5) Table of Contents Filed pursuant to Rule 424(b)(5) Registration Statement No.

January 16, 2013 424B5

Prospectus Supplement to Prospectus dated December 28, 2012. InterMune, Inc. 2.50% Convertible Senior Notes due 2017

Filed Pursuant to Rule 424(b)(5) Table of Contents Filed pursuant to Rule 424(b)(5) Registration Statement No.

January 16, 2013 FWP

InterMune, Inc. Concurrent Offerings of 13,500,000 Shares of Common Stock (the “Common Stock Offering”) $105,000,000 principal amount of 2.50% Convertible Senior Notes due 2017 (the “Convertible Senior Notes Offering”)

Free Writing Prospectus Pricing Term Sheet Filed pursuant to Rule 433 dated January 15, 2013 Registration File No.

January 14, 2013 424B5

Subject to Completion. Dated January 14, 2013. Prospectus Supplement to Prospectus dated December 28, 2012. 12,500,000 Shares InterMune, Inc. Common Stock

Filed Pursuant to Rule 424(b)(5) Table of Contents Filed pursuant to Rule 424(b)(5) Registration Statement No.

January 14, 2013 8-K

Financial Statements and Exhibits, Other Events - FORM 8-K

Form 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 14, 2013 INTERMUNE, INC. (Exact name of registrant as specified in its charter) Delaware 0-29801 94-3296648 (State or other jurisdiction of incorporation) (Commission

January 14, 2013 EX-99.2

RISK FACTORS

Risk Factors Exhibit 99.2 RISK FACTORS Investing in our common stock involves a high degree of risk. Before deciding whether to invest in our common stock, you should consider carefully the risk factors described below. If any of these risks actually occur, it may materially harm our business, financial condition, operating results or cash flow. As a result, the market price of our common stock co

January 14, 2013 EX-99.1

INTERMUNE ANNOUNCES PROPOSED CONCURRENT PUBLIC OFFERINGS OF COMMON STOCK AND CONVERTIBLE DEBT

Press Release Exhibit 99.1 Contact: Jim Goff, InterMune, Inc., 415-466-2228, [email protected] INTERMUNE ANNOUNCES PROPOSED CONCURRENT PUBLIC OFFERINGS OF COMMON STOCK AND CONVERTIBLE DEBT BRISBANE, Calif., January 14, 2013 — InterMune, Inc. (Nasdaq: ITMN) today announced that it plans to offer, subject to market and other conditions, $85.0 million aggregate principal amount of convertible senio

January 14, 2013 424B5

Subject to Completion. Dated January 14, 2013. Prospectus Supplement to Prospectus dated December 28, 2012. InterMune, Inc. % Convertible Senior Notes due 2017

Filed Pursuant to Rule 424(b)(5) Table of Contents Filed pursuant to Rule 424(b)(5) Registration Statement No.

January 7, 2013 8-K

Regulation FD Disclosure, Financial Statements and Exhibits - FORM 8-K

Form 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 7, 2013 INTERMUNE, INC. (Exact name of registrant as specified in its charter) Delaware 0-29801 94-3296648 (State or other jurisdiction of incorporation) (Commission

January 7, 2013 EX-99.1

J.P. Morgan 31st Annual

Company slide presentation J.P. Morgan 31st Annual Healthcare Conference January 7-10, 2013 Exhibit 99.1 2 Forward-looking Statements This presentation contains forward-looking statements made pursuant to the "safe harbor" provisions of the Private Securities Litigation Reform Act of 1995. Investors are cautioned that, without limitation, statements in this presentation regarding InterMune's plans

January 3, 2013 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition - FORM 8-K

Form 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 3, 2013 INTERMUNE, INC. (Exact name of registrant as specified in its charter) Delaware 0-29801 94-3296648 (State or other jurisdiction of incorporation) (Commission

January 3, 2013 EX-99.1

INTERMUNE REPORTS PRELIMINARY FOURTH QUARTER 2012 ESBRIET® (PIRFENIDONE) REVENUE AND OTHER RECENT BUSINESS HIGHLIGHTS – Reports Full Enrollment of Phase 3 ASCEND Trial – – Provides 2013 Revenue Guidance for Esbriet® –

Press Release Exhibit 99.1 Contact: Jim Goff, InterMune, Inc., 415-466-2228, [email protected] INTERMUNE REPORTS PRELIMINARY FOURTH QUARTER 2012 ESBRIET® (PIRFENIDONE) REVENUE AND OTHER RECENT BUSINESS HIGHLIGHTS – Reports Full Enrollment of Phase 3 ASCEND Trial – – Provides 2013 Revenue Guidance for Esbriet® – BRISBANE, Calif., January 3, 2013 — InterMune, Inc. (NASDAQ: ITMN) today announced un

December 17, 2012 S-3

- FORM S-3

Form S-3 Table of Contents As filed with the Securities and Exchange Commission on December 17, 2012 Registration No.

December 17, 2012 EX-12.1

COMPUTATION OF RATIO OF EARNINGS TO FIXED CHARGES Nine months ended September 30, Year ended December 31, 2012 2011 2010(A) 2009 2008 2007 (In thousands) Earnings: Income (loss) from continuing operations and before income taxes ($ 144,651 ) ($ 167,1

Statement regarding computation of ratios Exhibit 12.1 COMPUTATION OF RATIO OF EARNINGS TO FIXED CHARGES Nine months ended September 30, Year ended December 31, 2012 2011 2010(A) 2009 2008 2007 (In thousands) Earnings: Income (loss) from continuing operations and before income taxes ($ 144,651 ) ($ 167,150 ) $ 109,228 ($ 131,875 ) ($ 126,993 ) ($ 130,180 ) Add: Fixed Charges 6,763 6,998 9,367 11,0

December 17, 2012 EX-25.1

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM T-1 STATEMENT OF ELIGIBILITY UNDER THE TRUST INDENTURE ACT OF 1939 OF A CORPORATION DESIGNATED TO ACT AS TRUSTEE

Statement of Eligibility of Trustee on Form T-1 Exhibit 25.1 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM T-1 STATEMENT OF ELIGIBILITY UNDER THE TRUST INDENTURE ACT OF 1939 OF A CORPORATION DESIGNATED TO ACT AS TRUSTEE ¨ CHECK IF AN APPLICATION TO DETERMINE ELIGIBILITY OF A TRUSTEE PURSUANT TO SECTION 305(b)(2) THE BANK OF NEW YORK MELLON TRUST COMPANY, N.A. (Exact

November 30, 2012 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers - FORM 8-K

Form 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 26, 2012 INTERMUNE, INC. (Exact name of registrant as specified in its charter) Delaware 0-29801 94-3296648 (State or other jurisdiction of incorporation) (Commissio

November 29, 2012 8-K

Other Events - FORM 8-K

Form 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 29, 2012 INTERMUNE, INC. (Exact name of registrant as specified in its charter) Delaware 0-29801 94-3296648 (State or other jurisdiction of incorporation) (Commissio

November 13, 2012 S-8

- FORM S-8

Form S-8 As filed with the Securities and Exchange Commission on November 13, 2012 Registration No.

November 7, 2012 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition - FORM 8-K

Form 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 7, 2012 INTERMUNE, INC. (Exact name of registrant as specified in its charter) Delaware (State or other jurisdiction of incorporation) 0-29801 94-3296648 (Commission

November 7, 2012 EX-99.1

INTERMUNE REPORTS THIRD QUARTER 2012 FINANCIAL RESULTS AND BUSINESS HIGHLIGHTS

Press Release Exhibit 99.1 Contact: Jim Goff, InterMune, Inc., 415-466-2228, [email protected] INTERMUNE REPORTS THIRD QUARTER 2012 FINANCIAL RESULTS AND BUSINESS HIGHLIGHTS BRISBANE, Calif., November 7, 2012 — InterMune, Inc. (NASDAQ: ITMN) today announced results from operations for the third quarter and nine months ended September 30, 2012. InterMune reported Esbriet® (pirfenidone) net revenu

October 17, 2012 8-K

Other Events - FORM 8-K

Form 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 16, 2012 INTERMUNE, INC. (Exact name of registrant as specified in its charter) Delaware 0-29801 94-3296648 (State or other jurisdiction of incorporation) (Commission

October 16, 2012 SC 13G

ITMN / / Flynn James E Passive Investment

SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 SCHEDULE 13G (Rule 13d-102) INFORMATION TO BE INCLUDED IN STATEMENTS FILED PURSUANT TO RULES 13d-1(b)(c), AND (d) AND AMENDMENTS THERETO FILED PURSUANT TO RULE 13d-2(b) (Amendment No.

October 2, 2012 8-K

Other Events - FORM 8-K

Form 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): October 2, 2012 INTERMUNE, INC. (Exact name of registrant as specified in its charter) Delaware 0-29801 94-3296648 (State or other jurisdiction of incorporation) (Commission

September 11, 2012 8-K

Other Events - CURRENT REPORT ON FORM 8-K

Current Report on Form 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.

September 6, 2012 SC 13G/A

ITMN / / PRIMECAP MANAGEMENT CO/CA/ - SC 13G/A Passive Investment

OMB APPROVAL UNITED STATES OMB Number: 3235-0145 SECURITIES AND EXCHANGE COMMISSION Expires: February 28, 2009 Washington, D.

July 23, 2012 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition, Other Events - FORM 8-K

Form 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 23, 2012 INTERMUNE, INC. (Exact name of registrant as specified in its charter) Delaware 0-29801 94-3296648 (State or other jurisdiction of incorporation) (Commission Fi

July 23, 2012 EX-99.1

INTERMUNE REPORTS SECOND QUARTER 2012 FINANCIAL RESULTS AND BUSINESS HIGHLIGHTS – Finalizes price of Esbriet® in Germany –

Press Release Exhibit 99.1 Contact: Jim Goff, InterMune, Inc., 415-466-2228, [email protected] INTERMUNE REPORTS SECOND QUARTER 2012 FINANCIAL RESULTS AND BUSINESS HIGHLIGHTS – Finalizes price of Esbriet® in Germany – BRISBANE, Calif., July 23, 2012 — InterMune, Inc. (NASDAQ: ITMN) today announced results from operations for the second quarter and six months ended June 30, 2012. InterMune also r

July 6, 2012 8-K

Other Events - FORM 8-K

Form 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 5, 2012 INTERMUNE, INC. (Exact name of registrant as specified in its charter) Delaware 0-29801 94-3296648 (State or other jurisdiction of incorporation) (Commission Fil

June 20, 2012 8-K

- FORM 8-K

Form 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 19, 2012 INTERMUNE, INC. (Exact name of registrant as specified in its charter) Delaware 0-29801 94-3296648 (State or other jurisdiction of incorporation) (Commission Fi

June 8, 2012 EX-10.1

INTERMUNE, INC. AMENDED AND RESTATED 2000 EQUITY INCENTIVE PLAN Adopted January 31, 2000 Approved by Stockholders: March 20, 2000 Amended on: April 4, 2002 and June 19, 2002 Approved by Stockholders: June 19, 2002 Amended and Restated on: April 2, 20

Exhibit 10.1 INTERMUNE, INC. AMENDED AND RESTATED 2000 EQUITY INCENTIVE PLAN Adopted January 31, 2000 Approved by Stockholders: March 20, 2000 Amended on: April 4, 2002 and June 19, 2002 Approved by Stockholders: June 19, 2002 Amended and Restated on: April 2, 2004 Approved by Stockholders: May 27, 2004 Amended and Restated on: March 7, 2007 Amended on: April 27, 2007 Approved by Stockholders: May

June 8, 2012 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits, Submission of Matters to a Vote of Security Holders - FORM 8-K

Form 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 4, 2012 INTERMUNE, INC. (Exact name of registrant as specified in its charter) Delaware 0-29801 94-3296648 (State or other jurisdiction of incorporation) (Commission Fil

June 8, 2012 SC 13G

ITMN / / PRIMECAP MANAGEMENT CO/CA/ - SC 13G Passive Investment

OMB APPROVAL UNITED STATES OMB Number: 3235-0145 SECURITIES AND EXCHANGE COMMISSION Expires: February 28, 2009 Washington, D.

May 23, 2012 DEFA14A

- DEFINITIVE ADDITIONAL MATERIALS

Definitive Additional Materials UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.

May 21, 2012 8-K

Entry into a Material Definitive Agreement - FORM 8-K

Form 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 15, 2012 INTERMUNE, INC. (Exact name of registrant as specified in its charter) Delaware 0-29801 94-3296648 (State or other jurisdiction of incorporation) (Commission Fil

April 30, 2012 DEF 14A

- DEFINITIVE PROXY STATEMENT

Definitive Proxy Statement UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.

April 26, 2012 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers - FORM 8-K

Form 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 23, 2012 INTERMUNE, INC. (Exact name of registrant as specified in its charter) Delaware 0-29801 94-3296648 (State or other jurisdiction of incorporation) (Commission F

April 26, 2012 EX-99.1

INTERMUNE REPORTS FIRST QUARTER 2012 FINANCIAL RESULTS AND BUSINESS HIGHLIGHTS

Press Release Exhibit 99.1 Contact: Jim Goff, InterMune, Inc., 415-466-2228, [email protected] INTERMUNE REPORTS FIRST QUARTER 2012 FINANCIAL RESULTS AND BUSINESS HIGHLIGHTS BRISBANE, Calif., April 26, 2012 — InterMune, Inc. (NASDAQ: ITMN) today announced results from operations for the first quarter ended March 31, 2012. InterMune also highlighted its recent clinical development and business ac

April 26, 2012 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition - FORM 8-K

Form 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 26, 2012 INTERMUNE, INC. (Exact name of registrant as specified in its charter) Delaware (State or other jurisdiction of incorporation) 0-29801 94-3296648 (Commission F

April 10, 2012 SC 13G/A

ITMN / / SECTORAL ASSET MANAGEMENT INC - SC 13G/A Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 11)* INTERMUNE INC (Name of Issuer) COMMON STOCK (Title of Class of Securities) 45884X103 (CUSIP Number) MARCH 29, 2012 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which this Schedule is

April 5, 2012 8-K

Other Events - FORM 8-K

Form 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 5, 2012 INTERMUNE, INC. (Exact name of registrant as specified in its charter) Delaware 0-29801 94-3296648 (State or other jurisdiction of incorporation) (Commission Fi

March 27, 2012 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers - FORM 8-K

Form 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 26, 2012 INTERMUNE, INC. (Exact name of registrant as specified in its charter) Delaware 0-29801 94-3296648 (State or other jurisdiction of incorporation) (Commission F

March 15, 2012 8-K

Other Events - FORM 8-K

Form 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 15, 2012 INTERMUNE, INC. (Exact name of registrant as specified in its charter) Delaware (State or other jurisdiction of incorporation) 0-29801 (Commission File Number)

March 12, 2012 SC 13G/A

ITMN / / QVT Financial LP - AMENDMENT NO. 3 TO SCHEDULE 13G Passive Investment

Amendment No. 3 to Schedule 13G UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 3)* InterMune, Inc. (Name of Issuer) Common Stock, $0.001 par value per share (Title of Class of Securities) 45884X103 (CUSIP Number) March 1, 2012 (Date of Event Which Requires Filing of this Statement) Check the appropriate

February 14, 2012 SC 13G

ITMN / / BANK OF AMERICA CORP /DE/ - INTERMUNE INC 13G Passive Investment

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G UNDER THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No. )* INTERMUNE INC (Name of Issuer) Common Stock (Title of Class of Securities) 45884X103 (CUSIP Number) December 30, 2011 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the Rule pursuant to which this Schedule is filed: [X] R

February 14, 2012 SC 13G/A

ITMN / / D. E. Shaw Valence Portfolios, L.L.C. - AMENDMENT TO SCHEDULE 13G Passive Investment

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G (Amendment No. 1) Under the Securities Exchange Act of 1934 InterMune, Inc. (Name of Issuer) Common Stock, $0.001 par value (Title of Class of Securities) 45884X103 (CUSIP Number) December 31, 2011 (Date of Event Which Requires Filing of this Statement) Check the following box to designate the rule pursuant to which the Schedul

February 14, 2012 SC 13G/A

ITMN / / QVT Financial LP - SCHEDULE 13G AMENDMENT NO. 2 Passive Investment

Schedule 13G Amendment No. 2 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 2)* InterMune, Inc. (Name of Issuer) Common Stock, $0.001 par value per share (Title of Class of Securities) 45884X103 (CUSIP Number) December 31, 2011 (Date of Event Which Requires Filing of this Statement) Check the appropriate

February 14, 2012 EX-1

POWER OF ATTORNEY FOR CERTAIN REGULATORY FILINGS INCLUDING CERTAIN FILINGS UNDER THE SECURITIES EXCHANGE ACT OF 1934 AND THE INVESTMENT ADVISERS ACT OF 1940

Exhibit 1 POWER OF ATTORNEY FOR CERTAIN REGULATORY FILINGS INCLUDING CERTAIN FILINGS UNDER THE SECURITIES EXCHANGE ACT OF 1934 AND THE INVESTMENT ADVISERS ACT OF 1940 I, David E.

February 14, 2012 SC 13G/A

ITMN / / SAC Capital Advisors LP - AMENDMENT NO. 1 Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 1)* INTERMUNE, INC. (Name of Issuer) Common Stock, Par Value $0.001 Per Share (Title of Class of Securities) 45884X103 (CUSIP Number) December 31, 2011 (Date of Event which Requires Filing of this Statement) Check the appropriate box to designate the rule pu

February 14, 2012 SC 13G/A

ITMN / / SECTORAL ASSET MANAGEMENT INC - SC 13G/A Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 10)* INTERMUNE INC (Name of Issuer) COMMON STOCK (Title of Class of Securities) 45884X103 (CUSIP Number) DECEMBER 31, 2011 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which this Schedule

February 10, 2012 SC 13G/A

ITMN / / Visium Asset Management, LP - AMENDMENT NO. 5 Passive Investment

SC 13G/A 1 d299422dsc13ga.htm AMENDMENT NO. 5 SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 5)* InterMune, Inc. (Name of Issuer) COMMON STOCK, $.001 PER SHARE (Title of Class of Securities) 45884X103 (CUSIP Number) December 31, 2011 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to

February 10, 2012 SC 13G

ITMN / / PRICE T ROWE ASSOCIATES INC /MD/ - ITMN AS OF 12/31/2011 Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* INTERMUNE INC (Name of Issuer) COMMON STOCK (Title of Class of Securities) 45884X103 (CUSIP Number) December 31, 2011 (Date of Event which Requires Filing of Statement) Check the appropriate box to designate the Rule pursuant to which this Schedule is fil

February 10, 2012 SC 13G

ITMN / / COLUMBIA WANGER ASSET MANAGEMENT LLC - SCHEDULE 13G Passive Investment

Schedule 13G SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G UNDER THE SECURITIES EXCHANGE ACT OF 1934 (Amendment No. )* INTERMUNE INC (Name of Issuer) COMMON STOCK (Title of Class of Securities) 45884X103 (CUSIP Number) December 31, 2011 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the Rule pursuant to which this Schedule is

February 9, 2012 EX-10.1

3280 Bayshore Boulevard, Brisbane, CA 94005 Tel: 415.466.2200 Fax: 415.466.2300

Employment Offer Letter Exhibit 10.1 January 27, 2012 Jonathan A. Leff, M.D. 178 Seminary Drive Menlo Park, CA 94025 650.421.6618 Re: Employment with InterMune, Inc. Dear Jonathan: On behalf of InterMune, Inc., I am pleased to extend to you this official offer of employment with InterMune as Executive Vice President, Research and Development, reporting to Dan Welch, Chairman, CEO & President in ou

February 9, 2012 EX-99.1

INTERMUNE REPORTS FOURTH QUARTER AND FULL YEAR 2011 FINANCIAL RESULTS AND BUSINESS HIGHLIGHTS

Press Release Exhibit 99.1 Contact: Jim Goff, InterMune, Inc., 415-466-2228, [email protected] INTERMUNE REPORTS FOURTH QUARTER AND FULL YEAR 2011 FINANCIAL RESULTS AND BUSINESS HIGHLIGHTS BRISBANE, Calif., February 9, 2012 — InterMune, Inc. (NASDAQ: ITMN) today announced results from operations for the fourth quarter and full year ended December 31, 2011. InterMune reported product revenue in t

February 9, 2012 EX-99.2

INTERMUNE NAMES JONATHAN A. LEFF, M.D., AS EXECUTIVE VICE PRESIDENT OF RESEARCH AND DEVELOPMENT

Press Release Exhibit 99.2 Contact: Jim Goff, InterMune, Inc., 415-466-2228, [email protected] INTERMUNE NAMES JONATHAN A. LEFF, M.D., AS EXECUTIVE VICE PRESIDENT OF RESEARCH AND DEVELOPMENT BRISBANE, Calif., February 9, 2012 — InterMune, Inc. (NASDAQ: ITMN) today announced that Jonathan A. Leff, M.D., has been appointed InterMune’s Executive Vice President of Research and Development, effective

February 9, 2012 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits, Results of Operations and Financial Condition - FORM 8-K

Form 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 9, 2012 INTERMUNE, INC. (Exact name of registrant as specified in its charter) Delaware 0-29801 94-3296648 (State or other jurisdiction of incorporation) (Commission

February 8, 2012 SC 13G

ITMN / / FRANKLIN RESOURCES INC Passive Investment

inte11in.htm - Generated by SEC Publisher for SEC Filing CUSIP NO. 45884X103 13G Page 1 of 15 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* InterMune, Inc. (Name of Issuer) Common Stock, $0.001 par value (Title of Class of Securities) 45884X103 (CUSIP Number) December 31, 2011 (Date of Event Which Re

January 5, 2012 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 5, 2012 INTERMUNE, INC. (Exact name of registrant as specified in its charter) Delaware (State or other jurisdiction of incorporation) 0-29801 94-3296648 (Commission File Numb

January 5, 2012 EX-99.1

INTERMUNE REPORTS PRELIMINARY FOURTH QUARTER 2011 ESBRIET® (PIRFENIDONE) REVENUE AND OTHER RECENT BUSINESS HIGHLIGHTS – Company to host conference call and webcast today at 8:30 a.m. EST –

Press Release Exhibit 99.1 Contact: Jim Goff, InterMune, Inc., 415-466-2228, [email protected] INTERMUNE REPORTS PRELIMINARY FOURTH QUARTER 2011 ESBRIET® (PIRFENIDONE) REVENUE AND OTHER RECENT BUSINESS HIGHLIGHTS – Company to host conference call and webcast today at 8:30 a.m. EST – BRISBANE, Calif., January 5, 2012 — InterMune, Inc. (NASDAQ: ITMN) today announced unaudited net sales of Esbriet®

December 13, 2011 CORRESP

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Correspondence December 13, 2011 Mr. Jim B. Rosenberg Senior Assistant Chief Accountant Securities and Exchange Commission Division of Corporation Finance Washington D.C. 20549 Re: InterMune, Inc. Form 10-K for the Year Ended December 31, 2010 Filed March 9, 2011 Form 10-Q for the Quarterly Period Ended September 30, 2011 Filed November 7, 2011 File No. 000-29801 Dear Mr. Rosenberg, We are furnish

November 29, 2011 CORRESP

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Correspondence [InterMune Letterhead] November 29, 2011 VIA EDGAR and FEDERAL EXPRESS Senior Assistant Chief Accountant United States Securities and Exchange Commission Division of Corporation Finance 100 F Street, N.

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