RLYP Insider Trading - Relypsa, Inc.

Saham Orang Dalam

17,834,860 shares

Skor Sentimen Orang Dalam

Skor Sentimen Orang Dalam mengidentifikasi perusahaan yang dibeli oleh orang dalam korporat.

Ini adalah hasil dari model kuantitatif multifaktor yang canggih yang mengidentifikasi perusahaan dengan tingkat akumulasi internal tertinggi. Model penilaian ini menggunakan kombinasi dari jumlah bersih orang dalam yang membeli dalam 90 hari sebelumnya, total saham yang dibeli sebagai persentase dari jumlah saham yang beredar, dan total saham yang dimiliki oleh orang dalam. Angka tersebut berkisar dari 0 hingga 100, dengan angka yang lebih tinggi menunjukkan tingkat akumulasi yang lebih tinggi dibandingkan dengan perusahaan sejenis, dan 50 adalah rata-rata.

Frekuensi Pembaruan: Setiap Hari

Lihat Pilihan Teratas dari Orang Dalam, yang menyediakan daftar perusahaan dengan akumulasi orang dalam tertinggi.

Lihat Saham dengan Peringkat Tertinggi

Skor Sentimen Petugas

Skor Sentimen Pejabat menemukan perusahaan yang dibeli oleh Pejabat Korporat.

Menurut definisi, Pejabat Korporasi adalah Orang Dalam Korporasi, tetapi tidak seperti beberapa Orang Dalam lainnya (Pemegang Saham 10% dan Anggota Dewan), Pejabat bekerja untuk perusahaan setiap hari, dan mereka menggunakan uang mereka sendiri saat bertransaksi . (Pemegang Saham 10% dan Anggota Dewan seringkali adalah manajer dana yang mengelola uang orang lain.) Dengan demikian, transaksi orang dalam yang dilakukan oleh Pejabat jauh lebih signifikan dan harus ditangani dengan tepat.

Seperti Skor Sentimen Internal, Skor Sentimen Pejabat adalah hasil dari model kuantitatif multi-faktor yang canggih yang mengidentifikasi perusahaan dengan tingkat akumulasi pejabat tertinggi.

Frekuensi Pembaruan: Setiap Hari

Lihat Pilihan Teratas dari Orang Dalam, yang menyediakan daftar perusahaan dengan sentimen orang dalam tertinggi.

Lihat Saham dengan Peringkat Tertinggi

Metrik Utama Orang Dalam

Kartu ini menunjukkan peringkat perusahaan berdasarkan berbagai metrik internal. Peringkat persentil menunjukkan bagaimana perusahaan ini dibandingkan dengan perusahaan lain di pasar AS. Peringkat yang lebih tinggi menunjukkan situasi yang lebih baik.

Sebagai contoh, secara umum diterima bahwa pembelian oleh orang dalam perusahaan adalah indikator positif, sehingga perusahaan dengan lebih banyak pembelian oleh orang dalam akan mendapat peringkat lebih tinggi daripada perusahaan dengan lebih sedikit pembelian oleh orang dalam (atau bahkan penjualan oleh orang dalam).

Jumlah Bersih Pembelian oleh Orang Dalam (Peringkat)

N/A

Jumlah Bersih Pembelian oleh Orang Dalam adalah total jumlah orang dalam yang membeli dikurangi total jumlah orang dalam yang menjual dalam 90 hari terakhir. Peringkat persentil ditunjukkan di sini (kisaran dari 0 hingga 100%).

Persentase Saham yang Dibeli oleh Orang Dalam (Peringkat)

N/A

Persentase Saham yang Dibeli oleh Orang Dalam adalah total jumlah saham yang dibeli oleh orang dalam dikurangi total jumlah saham yang dijual oleh orang dalam dalam 90 hari terakhir, dibagi dengan total jumlah saham yang beredar dan dikalikan dengan 100.

Grafik Perdagangan Orang Dalam

Grafik berikut menunjukkan Relypsa, Inc. transaksi orang dalam. Orang dalam adalah pejabat, direktur, atau investor signifikan dalam suatu perusahaan. Secara umum, melakukan transaksi di perusahaan mereka berdasarkan informasi material yang belum dipublikasikan adalah ilegal bagi orang dalam. Ini tidak berarti bahwa mereka dilarang melakukan transaksi apa pun di perusahaan mereka sendiri. Namun, mereka wajib melaporkan semua transaksi kepada SEC melalui Formulir 4.

Daftar Orang Dalam dan Metrik Profitabilitas

Tabel ini menampilkan daftar orang dalam yang diketahui, dan dibuat secara otomatis dari pengajuan yang diungkapkan kepada SEC. Selain nama, jabatan terbaru, dan sebutan direktur, pejabat, atau pemilik 10%, kami memberikan kepemilikan terbaru yang diungkapkan. Selain itu, jika memungkinkan, kami memberikan kinerja perdagangan historis untuk orang dalam tersebut. Kinerja perdagangan historis adalah rata-rata tertimbang dari kinerja transaksi pembelian pasar terbuka aktual yang dilakukan oleh orang dalam tersebut. Untuk informasi lebih lanjut tentang bagaimana ini dihitung, tonton webinar YouTube ini.

See our leaderboard of most profitable insider traders.

Orang Dalam	Rata-rata Keuntungan (%)	Saham Dimiliki	Terbagi Disesuaikan

Report errors via our new Insider Auditing Tool

Rekam Jejak Pembelian Orang Dalam - Analisis Keuntungan Jangka Pendek

Pada bagian ini, kami menganalisis profitabilitas setiap pembelian saham oleh orang dalam di pasar terbuka yang tidak direncanakan yang dilakukan di RLYP / Relypsa, Inc.. Analisis ini membantu memahami apakah orang dalam tersebut secara konsisten menghasilkan pengembalian abnormal, dan layak untuk diikuti. Analisis ini dilakukan selama satu tahun setelah setiap transaksi, dan hasilnya bersifat teoretis .

Tabel berikut menunjukkan pembelian pasar terbuka terbaru yang bukan bagian dari rencana perdagangan otomatis.

Tanggal Perdagangan	Orang Dalam	Dilaporkan Saham	Dilaporkan Harga	Disesuaikan Saham	Disesuaikan Harga	Dasar Biaya	Hari-hari menuju Maksimal
2016-08-17	DONDERO JAMES D	500	31.9210	500	31.9210	15,960	16
2016-03-16	BALL KRISTINE M	7,000	12.1500	7,000	12.1500	85,050
2016-03-15	Schuetz Thomas J.	30,000	13.3944	30,000	13.3944	401,832
2015-10-22	ORBIMED ADVISORS LLC	310,700	12.9200	310,700	12.9200	4,014,244
2015-10-22	ORBIMED ADVISORS LLC	189,300	11.9700	189,300	11.9700	2,265,921
2013-11-20	New Leaf Ventures I, L.P.	185,978	11.0000	185,978	11.0000	2,045,758
2013-11-20	Orwin John A	15,000	11.0000	15,000	11.0000	165,000

Harga yang Disesuaikan adalah harga yang disesuaikan dengan pemisahan saham. Ang Adjusted Shares ay ang jumlah saham yang disesuaikan dengan pemisahan saham (stock split).

Rekam Jejak Penjualan Orang Dalam - Analisis Kerugian Jangka Pendek

Dalam bagian ini, kami menganalisis penghindaran kerugian jangka pendek dari setiap penjualan dalam pasar terbuka yang tidak direncanakan oleh orang dalam yang dilakukan di RLYP / Relypsa, Inc.. Pola penghindaran kerugian yang konsisten dapat menunjukkan bahwa transaksi penjualan di masa mendatang dapat memprediksi penurunan harga. Analisis ini berlaku untuk satu tahun setelah setiap perdagangan, dan hasilnya bersifat teoretis .

Tabel berikut menunjukkan penjualan pasar terbuka terbaru yang bukan bagian dari rencana perdagangan otomatis.

Tanggal Perdagangan	Orang Dalam	Dilaporkan Saham	Dilaporkan Harga	Disesuaikan Saham	Disesuaikan Harga	Dasar Biaya	Hari-hari menuju Menit
2016-08-16	Montgomery Monte	510	31.9200	510	31.9200	16,279	17
2016-08-11	DONDERO JAMES D	37,000	31.9600	37,000	31.9600	1,182,520
2016-07-25	ORBIMED ADVISORS LLC	343,600	31.9800	343,600	31.9800	10,988,328
2016-07-22	ORBIMED ADVISORS LLC	3,700,000	32.0000	3,700,000	32.0000	118,400,000
2016-06-07	HASTINGS PAUL J	1,013	19.3218	1,013	19.3218	19,573
2016-06-07	Butler John P.	1,013	19.3192	1,013	19.3192	19,570
2016-06-07	Torley Helen	1,013	19.3187	1,013	19.3187	19,570
2016-06-07	Hillan Kenneth J.	1,013	19.3115	1,013	19.3115	19,563
2016-06-07	MCGIRR DAVID W J	1,013	19.3366	1,013	19.3366	19,588

Harga yang Disesuaikan adalah harga yang disesuaikan dengan pemisahan saham. Ang Adjusted Shares ay ang jumlah saham yang disesuaikan dengan pemisahan saham (stock split).

Riwayat Transaksi

Klik ikon tautan untuk melihat riwayat transaksi lengkap. Transaksi yang dilaporkan sebagai bagian dari rencana perdagangan otomatis 10b5-1 akan memiliki tanda X di kolom yang bertanda 10b-5.

Berkas Tanggal	Perdagangan Tanggal	Formulir	Orang Dalam	Ticker	Judul Keamanan	Kode	Langsung	Latihan Harga	Satuan Harga	Unit Diubah	Nilai Diubah (1 ribu)	Sisa Pilihan	Sisa Saham
2016-09-02	2016-09-01	4	BALL KRISTINE M	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	28.38		-38,500		0
2016-09-02	2016-09-01	4	BALL KRISTINE M	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	27.21		-35,000		0
2016-09-02	2016-09-01	4	BALL KRISTINE M	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	7.40		-43,603		0
2016-09-02	2016-09-01	4	BALL KRISTINE M	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	3.96		-122,872		0
2016-09-02	2016-09-01	4	BALL KRISTINE M	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	18.87		-25,000		0
2016-09-02	2016-09-01	4	BALL KRISTINE M	RLYP	Stock Option (Right to Buy)	A - Award	D	18.87		16,667		25,000
2016-09-02	2016-09-01	4	BALL KRISTINE M	RLYP	Common Stock	D - Sale to Issuer	D		32.0000	-20,355	-651		0
2016-09-02	2016-09-01	4	BALL KRISTINE M	RLYP	Common Stock	U - Other	D		32.0000	-11,922	-382		20,355
2016-09-02	2016-09-01	4	BALL KRISTINE M	RLYP	Common Stock	A - Award	D			4,167			32,277
2016-09-02	2016-09-01	4	HASTINGS PAUL J	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	35.79		-4,500		0
2016-09-02	2016-09-01	4	HASTINGS PAUL J	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	17.00		-4,500		0
2016-09-02	2016-09-01	4	HASTINGS PAUL J	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	23.96		-3,828		0
2016-09-02	2016-09-01	4	HASTINGS PAUL J	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	7.40		-15,953		0
2016-09-02	2016-09-01	4	HASTINGS PAUL J	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	3.96		-21,802		0
2016-09-02	2016-09-01	4	HASTINGS PAUL J	RLYP	Common Stock	D - Sale to Issuer	D		32.0000	-2,250	-72		0
2016-09-02	2016-09-01	4	HASTINGS PAUL J	RLYP	Common Stock	U - Other	D		32.0000	-2,495	-80		2,250
2016-09-02	2016-09-01	4	MCGIRR DAVID W J	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	17.00		-4,500		0
2016-09-02	2016-09-01	4	MCGIRR DAVID W J	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	35.79		-4,500		0
2016-09-02	2016-09-01	4	MCGIRR DAVID W J	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	23.96		-3,828		0
2016-09-02	2016-09-01	4	MCGIRR DAVID W J	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	7.40		-10,140		0
2016-09-02	2016-09-01	4	MCGIRR DAVID W J	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	3.96		-55,232		0
2016-09-02	2016-09-01	4	MCGIRR DAVID W J	RLYP	Common Stock	D - Sale to Issuer	D		32.0000	-2,250	-72		0
2016-09-02	2016-09-01	4	MCGIRR DAVID W J	RLYP	Common Stock	U - Other	D		32.0000	-2,729	-87		2,250
2016-09-02	2016-09-01	4	SPIEGELMAN DANIEL K	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	17.00		-4,500		0
2016-09-02	2016-09-01	4	SPIEGELMAN DANIEL K	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	35.79		-4,500		0
2016-09-02	2016-09-01	4	SPIEGELMAN DANIEL K	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	23.96		-12,000		0
2016-09-02	2016-09-01	4	SPIEGELMAN DANIEL K	RLYP	Common Stock	D - Sale to Issuer	D		32.0000	-2,250	-72		0
2016-09-02	2016-09-01	4	SPIEGELMAN DANIEL K	RLYP	Common Stock	U - Other	D		32.0000	-1,237	-40		2,250
2016-09-02	2016-09-01	4	Berman Lance	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	28.38		-38,500		0
2016-09-02	2016-09-01	4	Berman Lance	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	27.21		-35,000		0
2016-09-02	2016-09-01	4	Berman Lance	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	7.40		-25,414		0
2016-09-02	2016-09-01	4	Berman Lance	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	3.96		-21,765		0
2016-09-02	2016-09-01	4	Berman Lance	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	3.96		-10,668		0
2016-09-02	2016-09-01	4	Berman Lance	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	18.87		-25,000		0
2016-09-02	2016-09-01	4	Berman Lance	RLYP	Stock Option (Right to Buy)	A - Award	D	18.87		16,667		25,000
2016-09-02	2016-09-01	4	Berman Lance	RLYP	Common Stock	D - Sale to Issuer	D		32.0000	-20,355	-651		0
2016-09-02	2016-09-01	4	Berman Lance	RLYP	Common Stock	U - Other	D		32.0000	-4,922	-158		20,355
2016-09-02	2016-09-01	4	Berman Lance	RLYP	Common Stock	A - Award	D			4,167			25,277
2016-09-02	2016-09-01	4	Orwin John A	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	28.38		-105,000		0
2016-09-02	2016-09-01	4	Orwin John A	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	27.21		-94,500		0
2016-09-02	2016-09-01	4	Orwin John A	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	7.40		-727,877		0
2016-09-02	2016-09-01	4	Orwin John A	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	18.87		-67,500		0
2016-09-02	2016-09-01	4	Orwin John A	RLYP	Stock Option (Right to Buy)	A - Award	D	18.87		45,000		67,500
2016-09-02	2016-09-01	4	Orwin John A	RLYP	Common Stock	D - Sale to Issuer	D		32.0000	-55,000	-1,760		0
2016-09-02	2016-09-01	4	Orwin John A	RLYP	Common Stock	U - Other	D		32.0000	-10,142	-325		55,000
2016-09-02	2016-09-01	4	Orwin John A	RLYP	Common Stock	A - Award	D			11,250			65,142
2016-09-02	2016-09-01	4	Torley Helen	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	17.00		-4,500		0
2016-09-02	2016-09-01	4	Torley Helen	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	35.79		-4,500		0
2016-09-02	2016-09-01	4	Torley Helen	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	36.83		-12,000		0
2016-09-02	2016-09-01	4	Torley Helen	RLYP	Common Stock	D - Sale to Issuer	D		32.0000	-2,250	-72		0
2016-09-02	2016-09-01	4	Torley Helen	RLYP	Common Stock	U - Other	D		32.0000	-1,237	-40		2,250
2016-09-02	2016-09-01	4	Garland J. Scott	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	28.38		-35,000		0
2016-09-02	2016-09-01	4	Garland J. Scott	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	21.36		-100,000		0
2016-09-02	2016-09-01	4	Garland J. Scott	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	18.87		-25,000		0
2016-09-02	2016-09-01	4	Garland J. Scott	RLYP	Stock Option (Right to Buy)	A - Award	D	18.87		16,667		25,000
2016-09-02	2016-09-01	4	Garland J. Scott	RLYP	Common Stock	D - Sale to Issuer	D		32.0000	-16,042	-513		0
2016-09-02	2016-09-01	4	Garland J. Scott	RLYP	Common Stock	U - Other	D		32.0000	-2,470	-79		16,042
2016-09-02	2016-09-01	4	Garland J. Scott	RLYP	Common Stock	A - Award	D			4,167			18,512
2016-09-02	2016-09-01	4	Schuetz Thomas J.	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	35.79		-4,500		0
2016-09-02	2016-09-01	4	Schuetz Thomas J.	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	17.00		-4,500		0
2016-09-02	2016-09-01	4	Schuetz Thomas J.	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	23.96		-3,828		0
2016-09-02	2016-09-01	4	Schuetz Thomas J.	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	7.40		-10,140		0
2016-09-02	2016-09-01	4	Schuetz Thomas J.	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	3.96		-9,011		0
2016-09-02	2016-09-01	4	Schuetz Thomas J.	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	3.96		-15,697		0
2016-09-02	2016-09-01	4	Schuetz Thomas J.	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	4.65		-872		0
2016-09-02	2016-09-01	4	Schuetz Thomas J.	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	4.65		-1,744		0
2016-09-02	2016-09-01	4	Schuetz Thomas J.	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	4.65		-581		0
2016-09-02	2016-09-01	4	Schuetz Thomas J.	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	4.65		-6,976		0
2016-09-02	2016-09-01	4	Schuetz Thomas J.	RLYP	Common Stock	D - Sale to Issuer	D		32.0000	-2,250	-72		0
2016-09-02	2016-09-01	4	Schuetz Thomas J.	RLYP	Common Stock	U - Other	D		32.0000	-33,962	-1,087		2,250
2016-09-02	2016-09-01	4	Butler John P.	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	35.79		-4,500		0
2016-09-02	2016-09-01	4	Butler John P.	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	17.00		-4,500		0
2016-09-02	2016-09-01	4	Butler John P.	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	23.96		-3,828		0
2016-09-02	2016-09-01	4	Butler John P.	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	11.00		-24,632		0
2016-09-02	2016-09-01	4	Butler John P.	RLYP	Common Stock	D - Sale to Issuer	D		32.0000	-2,250	-72		0
2016-09-02	2016-09-01	4	Butler John P.	RLYP	Common Stock	U - Other	D		32.0000	-2,849	-91		2,250
2016-09-02	2016-09-01	4	Stahl Wilhelm	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	27.21		-24,500		0
2016-09-02	2016-09-01	4	Stahl Wilhelm	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	28.38		-24,500		0
2016-09-02	2016-09-01	4	Stahl Wilhelm	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	7.40		-37,789		0
2016-09-02	2016-09-01	4	Stahl Wilhelm	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	3.96		-46,597		0
2016-09-02	2016-09-01	4	Stahl Wilhelm	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	3.96		-27,759		0
2016-09-02	2016-09-01	4	Stahl Wilhelm	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	18.87		-17,500		0
2016-09-02	2016-09-01	4	Stahl Wilhelm	RLYP	Stock Option (Right to Buy)	A - Award	D	18.87		11,667		17,500
2016-09-02	2016-09-01	4	Stahl Wilhelm	RLYP	Common Stock	D - Sale to Issuer	D		32.0000	-14,167	-453		0
2016-09-02	2016-09-01	4	Stahl Wilhelm	RLYP	Common Stock	U - Other	D		32.0000	-3,479	-111		14,167
2016-09-02	2016-09-01	4	Stahl Wilhelm	RLYP	Common Stock	A - Award	D			2,917			17,646
2016-09-02	2016-09-01	4	Krasnow Ronald A.	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	28.38		-24,500		0
2016-09-02	2016-09-01	4	Krasnow Ronald A.	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	27.21		-24,500		0
2016-09-02	2016-09-01	4	Krasnow Ronald A.	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	7.40		-43,603		0
2016-09-02	2016-09-01	4	Krasnow Ronald A.	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	3.96		-37,611		0
2016-09-02	2016-09-01	4	Krasnow Ronald A.	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	3.96		-8,783		0
2016-09-02	2016-09-01	4	Krasnow Ronald A.	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	4.65		-17,441		0
2016-09-02	2016-09-01	4	Krasnow Ronald A.	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	18.87		-17,500		0
2016-09-02	2016-09-01	4	Krasnow Ronald A.	RLYP	Stock Option (Right to Buy)	A - Award	D	18.87		11,667		17,500
2016-09-02	2016-09-01	4	Krasnow Ronald A.	RLYP	Common Stock	D - Sale to Issuer	D		32.0000	-14,167	-453		0
2016-09-02	2016-09-01	4	Krasnow Ronald A.	RLYP	Common Stock	U - Other	D		32.0000	-3,479	-111		14,167
2016-09-02	2016-09-01	4	Krasnow Ronald A.	RLYP	Common Stock	A - Award	D			2,917			17,646
2016-09-02	2016-09-01	4	Corbett Mary	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	27.21		-24,500		0
2016-09-02	2016-09-01	4	Corbett Mary	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	28.38		-24,500		0
2016-09-02	2016-09-01	4	Corbett Mary	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	33.76		-50,000		0
2016-09-02	2016-09-01	4	Corbett Mary	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	18.87		-17,500		0
2016-09-02	2016-09-01	4	Corbett Mary	RLYP	Stock Option (Right to Buy)	A - Award	D	18.87		11,667		17,500
2016-09-02	2016-09-01	4	Corbett Mary	RLYP	Common Stock	D - Sale to Issuer	D		32.0000	-14,167	-453		0
2016-09-02	2016-09-01	4	Corbett Mary	RLYP	Common Stock	U - Other	D		32.0000	-6,080	-195		14,167
2016-09-02	2016-09-01	4	Corbett Mary	RLYP	Common Stock	A - Award	D			2,917			20,247
2016-09-02	2016-09-01	4	Hillan Kenneth J.	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	17.00		-4,500		0
2016-09-02	2016-09-01	4	Hillan Kenneth J.	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	35.79		-4,500		0
2016-09-02	2016-09-01	4	Hillan Kenneth J.	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	23.96		-12,000		0
2016-09-02	2016-09-01	4	Hillan Kenneth J.	RLYP	Common Stock	D - Sale to Issuer	D		32.0000	-2,250	-72		0
2016-09-02	2016-09-01	4	Hillan Kenneth J.	RLYP	Common Stock	U - Other	D		32.0000	-1,237	-40		2,250
2016-09-02	2016-09-01	4	Harrison Stephen D	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	28.38		-35,000		0
2016-09-02	2016-09-01	4	Harrison Stephen D	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	30.80		-75,000		0
2016-09-02	2016-09-01	4	Harrison Stephen D	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	18.87		-25,000		0
2016-09-02	2016-09-01	4	Harrison Stephen D	RLYP	Stock Option (Right to Buy)	A - Award	D	18.87		16,667		25,000
2016-09-02	2016-09-01	4	Harrison Stephen D	RLYP	Common Stock	D - Sale to Issuer	D		32.0000	-16,042	-513		0
2016-09-02	2016-09-01	4	Harrison Stephen D	RLYP	Common Stock	U - Other	D		32.0000	-5,969	-191		16,042
2016-09-02	2016-09-01	4	Harrison Stephen D	RLYP	Common Stock	A - Award	D			4,167			22,011
2016-09-02	2016-09-01	4	Montgomery Monte	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	28.38		-11,200		0
2016-09-02	2016-09-01	4	Montgomery Monte	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	27.21		-14,000		0
2016-09-02	2016-09-01	4	Montgomery Monte	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	7.40		-2,907		0
2016-09-02	2016-09-01	4	Montgomery Monte	RLYP	Stock Option (Right to Buy)	D - Sale to Issuer	D	4.99		-2,059		0
2016-09-02	2016-09-01	4	Montgomery Monte	RLYP	Common Stock	D - Sale to Issuer	D		32.0000	-13,200	-422		0
2016-09-02	2016-09-01	4	Montgomery Monte	RLYP	Common Stock	U - Other	D		32.0000	-2,066	-66		13,200
2016-09-02	2016-09-01	4	Montgomery Monte	RLYP	Common Stock	A - Award	D			2,200			15,266
2016-08-18	2016-08-17	4	DONDERO JAMES D	RLYP	Common stock, par value $0.001 per share	P - Purchase	I		31.9210	500	16		128,500
2016-08-18	2016-08-16	4	Montgomery Monte	RLYP	Common Stock	S - Sale	D		31.9200	-510	-16		12,539
2016-08-17	2016-08-15	4	BALL KRISTINE M	RLYP	Common Stock	F - Taxes	D		31.8900	-1,480	-47		28,110
2016-08-17	2016-08-15	4	Berman Lance	RLYP	Common Stock	F - Taxes	D		31.8900	-1,480	-47		21,110
2016-08-17	2016-08-15	4	Orwin John A	RLYP	Common Stock	F - Taxes	D		31.8900	-3,994	-127		53,892
2016-08-17	2016-08-15	4	Garland J. Scott	RLYP	Common Stock	F - Taxes	D		31.8900	-705	-22		14,345
2016-08-17	2016-08-15	4	Stahl Wilhelm	RLYP	Common Stock	F - Taxes	D		31.8900	-1,034	-33		14,729
2016-08-17	2016-08-15	4	Krasnow Ronald A.	RLYP	Common Stock	F - Taxes	D		31.8900	-1,034	-33		14,729
2016-08-17	2016-08-15	4	Corbett Mary	RLYP	Common Stock	F - Taxes	D		31.8900	-1,034	-33		17,330
2016-08-17	2016-08-15	4	Harrison Stephen D	RLYP	Common Stock	F - Taxes	D		31.8900	-705	-22		17,844
2016-08-15	2016-08-11	4	DONDERO JAMES D	RLYP	Option to purchase Common stock, par value $0.001 per share	P - Purchase	I	32.00	0.1500	5,000	1	65,799
2016-08-15	2016-08-11	4	DONDERO JAMES D	RLYP	Common stock, par value $0.001 per share	S - Sale	I		31.9600	-37,000	-1,183		128,000
2016-08-10		3	Montgomery Monte	RLYP	Common Stock		D						26,098
2016-08-10		3	Montgomery Monte	RLYP	Common Stock		D						26,098
2016-08-09	2016-08-05	4	DONDERO JAMES D	RLYP	Option to purchase Common stock, par value $0.001 per share	P - Purchase	I	32.00	0.1500	3,300	0	60,799
2016-08-08		3	DONDERO JAMES D	RLYP	Common stock, par value $0.001 per share		I						330,000
2016-08-08		3	DONDERO JAMES D	RLYP	Common stock, par value $0.001 per share		I						330,000
2016-07-26	2016-07-25	4	ORBIMED ADVISORS LLC See Footnotes	RLYP	Common Stock	S - Sale	I		31.9800	-343,600	-10,988		3,356,400
2016-07-26	2016-07-22	4	ORBIMED ADVISORS LLC See Footnotes	RLYP	Common Stock	S - Sale	I		32.0000	-3,700,000	-118,400		3,700,000
2016-06-23	2016-06-21	4	SPIEGELMAN DANIEL K	RLYP	Stock Option (Right to Buy)	A - Award	D	17.00		4,500		4,500
2016-06-23	2016-06-21	4	SPIEGELMAN DANIEL K	RLYP	Common Stock	A - Award	D			2,250			3,487
2016-06-23	2016-06-21	4	HASTINGS PAUL J	RLYP	Stock Option (Right to Buy)	A - Award	D	17.00		4,500		4,500
2016-06-23	2016-06-21	4	HASTINGS PAUL J	RLYP	Common Stock	A - Award	D			2,250			4,745
2016-06-23	2016-06-21	4	MCGIRR DAVID W J	RLYP	Stock Option (Right to Buy)	A - Award	D	17.00		4,500		4,500
2016-06-23	2016-06-21	4	MCGIRR DAVID W J	RLYP	Common Stock	A - Award	D			2,250			4,979
2016-06-23	2016-06-21	4	Torley Helen	RLYP	Stock Option (Right to Buy)	A - Award	D	17.00		4,500		4,500
2016-06-23	2016-06-21	4	Torley Helen	RLYP	Common Stock	A - Award	D			2,250			3,487
2016-06-23	2016-06-21	4	Schuetz Thomas J.	RLYP	Stock Option (Right to Buy)	A - Award	D	17.00		4,500		4,500
2016-06-23	2016-06-21	4	Schuetz Thomas J.	RLYP	Common Stock	A - Award	D			2,250			36,212
2016-06-23	2016-06-21	4	Butler John P.	RLYP	Stock Option (Right to Buy)	A - Award	D	17.00		4,500		4,500
2016-06-23	2016-06-21	4	Butler John P.	RLYP	Common Stock	A - Award	D			2,250			5,099
2016-06-23	2016-06-21	4	Hillan Kenneth J.	RLYP	Stock Option (Right to Buy)	A - Award	D	17.00		4,500		4,500
2016-06-23	2016-06-21	4	Hillan Kenneth J.	RLYP	Common Stock	A - Award	D			2,250			3,487
2016-06-08	2016-06-07	4	MCGIRR DAVID W J	RLYP	Common Stock	S - Sale	D		19.3366	-1,013	-20		2,729
2016-06-08	2016-06-07	4	HASTINGS PAUL J	RLYP	Common Stock	S - Sale	D		19.3218	-1,013	-20		2,495
2016-06-08	2016-06-07	4	SPIEGELMAN DANIEL K	RLYP	Common Stock	S - Sale	D		19.3106	-1,013	-20		1,237
2016-06-08	2016-06-07	4	Torley Helen	RLYP	Common Stock	S - Sale	D		19.3187	-1,013	-20		1,237
2016-06-08	2016-06-07	4	Butler John P.	RLYP	Common Stock	S - Sale	D		19.3192	-1,013	-20		2,849
2016-06-08	2016-06-07	4	Hillan Kenneth J.	RLYP	Common Stock	S - Sale	D		19.3115	-1,013	-20		1,237
2016-06-07	2016-06-03	4	BALL KRISTINE M	RLYP	Stock Option (Right to Buy)	A - Award	D	18.87		8,333		8,333
2016-06-07	2016-06-03	4	BALL KRISTINE M	RLYP	Common Stock	F - Taxes	D		19.9600	-783	-16		29,590
2016-06-07	2016-06-03	4	BALL KRISTINE M	RLYP	Common Stock	A - Award	D			2,083			30,373
2016-06-07	2016-06-03	4	Berman Lance	RLYP	Stock Option (Right to Buy)	A - Award	D	18.87		8,333		8,333
2016-06-07	2016-06-03	4	Berman Lance	RLYP	Common Stock	F - Taxes	D		19.9600	-783	-16		22,590
2016-06-07	2016-06-03	4	Berman Lance	RLYP	Common Stock	A - Award	D			2,083			23,373
2016-06-07	2016-06-03	4	Orwin John A	RLYP	Stock Option (Right to Buy)	A - Award	D	18.87		22,500		22,500
2016-06-07	2016-06-03	4	Orwin John A	RLYP	Common Stock	F - Taxes	D		19.9600	-2,114	-42		57,886
2016-06-07	2016-06-03	4	Orwin John A	RLYP	Common Stock	A - Award	D			5,625			60,000
2016-06-07	2016-06-03	4	Garland J. Scott	RLYP	Stock Option (Right to Buy)	A - Award	D	18.87		8,333		8,333
2016-06-07	2016-06-03	4	Garland J. Scott	RLYP	Common Stock	F - Taxes	D		19.9600	-783	-16		15,050
2016-06-07	2016-06-03	4	Garland J. Scott	RLYP	Common Stock	A - Award	D			2,083			15,833
2016-06-07	2016-06-03	4	Stahl Wilhelm	RLYP	Stock Option (Right to Buy)	A - Award	D	18.87		5,833		5,833
2016-06-07	2016-06-03	4	Stahl Wilhelm	RLYP	Common Stock	F - Taxes	D		19.9600	-548	-11		15,763
2016-06-07	2016-06-03	4	Stahl Wilhelm	RLYP	Common Stock	A - Award	D			1,458			16,311
2016-06-07	2016-06-03	4	Krasnow Ronald A.	RLYP	Stock Option (Right to Buy)	A - Award	D	18.87		5,833		5,833
2016-06-07	2016-06-03	4	Krasnow Ronald A.	RLYP	Common Stock	F - Taxes	D		19.9600	-548	-11		15,763
2016-06-07	2016-06-03	4	Krasnow Ronald A.	RLYP	Common Stock	A - Award	D			1,458			16,311
2016-06-07	2016-06-03	4	Corbett Mary	RLYP	Stock Option (Right to Buy)	A - Award	D	18.87		5,833		5,833
2016-06-07	2016-06-03	4	Corbett Mary	RLYP	Common Stock	F - Taxes	D		19.9600	-548	-11		18,364
2016-06-07	2016-06-03	4	Corbett Mary	RLYP	Common Stock	A - Award	D			1,458			18,912
2016-06-07	2016-06-03	4	Harrison Stephen D	RLYP	Stock Option (Right to Buy)	A - Award	D	18.87		8,333		8,333
2016-06-07	2016-06-03	4	Harrison Stephen D	RLYP	Common Stock	F - Taxes	D		19.9600	-783	-16		18,549
2016-06-07	2016-06-03	4	Harrison Stephen D	RLYP	Common Stock	A - Award	D			2,083			19,332
2016-03-16	2016-03-16	4	BALL KRISTINE M	RLYP	Common Stock	P - Purchase	D		12.1500	7,000	85		28,290
2016-03-16	2016-03-15	4	Schuetz Thomas J.	RLYP	Common Stock	P - Purchase	D		13.3944	30,000	402		33,962
2016-03-16	2016-02-29	4	Corbett Mary	RLYP	Common Stock	A - Award	D		11.2710	1,274	14		17,454
2016-03-16	2016-02-29	4	Harrison Stephen D	RLYP	Common Stock	A - Award	D		11.2710	2,218	25		17,249
2016-01-04	2015-12-31	4	Stahl Wilhelm	RLYP	Stock Option (right to buy)	M - Exercise	D	3.96		-3,709		46,597
2016-01-04	2015-12-31	4	Stahl Wilhelm	RLYP	Stock Option (right to buy)	M - Exercise	D	3.96		-16,291		27,759
2016-01-04	2015-12-31	4	Stahl Wilhelm	RLYP	Common Stock	S - Sale	D		28.5279	-20,000	-571		14,853
2016-01-04	2015-12-31	4	Stahl Wilhelm	RLYP	Common Stock	M - Exercise	D		3.9600	3,709	15		34,853
2016-01-04	2015-12-31	4	Stahl Wilhelm	RLYP	Common Stock	M - Exercise	D		3.9600	16,291	65		31,144
2015-12-23	2015-12-23	4	ORBIMED ADVISORS LLC See Footnotes	RLYP	Common Stock	S - Sale	I		27.5400	-52,058	-1,434		7,400,000
2015-12-23	2015-12-23	4	ORBIMED ADVISORS LLC See Footnotes	RLYP	Common Stock	S - Sale	I		26.7800	-47,942	-1,284		7,452,058
2015-12-23	2015-12-22	4	ORBIMED ADVISORS LLC See Footnotes	RLYP	Common Stock	S - Sale	I		27.0200	-38,630	-1,044		7,500,000
2015-12-23	2015-12-22	4	ORBIMED ADVISORS LLC See Footnotes	RLYP	Common Stock	S - Sale	I		26.3900	-111,370	-2,939		7,538,630
2015-12-23	2015-12-21	4	ORBIMED ADVISORS LLC See Footnotes	RLYP	Common Stock	S - Sale	I		28.3900	-14,171	-402		7,650,000
2015-12-23	2015-12-21	4	ORBIMED ADVISORS LLC See Footnotes	RLYP	Common Stock	S - Sale	I		27.5000	-235,829	-6,485		7,664,171
2015-12-09	2015-12-07	4	Orwin John A	RLYP	Stock Option (right to buy)	M - Exercise	D	7.40		-10,000		727,877
2015-12-09	2015-12-07	4	Orwin John A	RLYP	Common Stock	S - Sale	D		29.6658	-800	-24		54,375
2015-12-09	2015-12-07	4	Orwin John A	RLYP	Common Stock	S - Sale	D		28.5202	-7,379	-210		55,175
2015-12-09	2015-12-07	4	Orwin John A	RLYP	Common Stock	S - Sale	D		27.8477	-6,821	-190		62,554
2015-12-09	2015-12-07	4	Orwin John A	RLYP	Common Stock	M - Exercise	D		7.4000	10,000	74		69,375
2015-12-09	2015-12-09	4	Berman Lance	RLYP	Stock Option (right to buy)	M - Exercise	D	7.40		-750		25,414
2015-12-09	2015-12-09	4	Berman Lance	RLYP	Common Stock	S - Sale	D		29.5000	-750	-22		21,290
2015-12-09	2015-12-09	4	Berman Lance	RLYP	Common Stock	M - Exercise	D		7.4000	750	6		22,040
2015-12-09	2015-12-07	4	Berman Lance	RLYP	Stock Option (right to buy)	M - Exercise	D	7.40		-4,755		26,164
2015-12-09	2015-12-07	4	Berman Lance	RLYP	Stock Option (right to buy)	M - Exercise	D	3.96		-11,349		21,765
2015-12-09	2015-12-07	4	Berman Lance	RLYP	Stock Option (right to buy)	M - Exercise	D	3.96		-13,896		10,668
2015-12-09	2015-12-07	4	Berman Lance	RLYP	Common Stock	S - Sale	D		29.7800	-30,000	-893		21,290
2015-12-09	2015-12-07	4	Berman Lance	RLYP	Common Stock	M - Exercise	D		7.4000	4,755	35		51,290
2015-12-09	2015-12-07	4	Berman Lance	RLYP	Common Stock	M - Exercise	D		3.9600	11,349	45		46,535
2015-12-09	2015-12-07	4	Berman Lance	RLYP	Common Stock	M - Exercise	D		3.9600	13,896	55		35,186
2015-12-04	2015-12-04	4	Orwin John A	RLYP	Stock Option (right to buy)	M - Exercise	D	7.40		-20,000		737,877
2015-12-04	2015-12-04	4	Orwin John A	RLYP	Common Stock	S - Sale	D		25.0000	-20,000	-500		59,375
2015-12-04	2015-12-04	4	Orwin John A	RLYP	Common Stock	M - Exercise	D		7.4000	20,000	148		79,375
2015-12-04	2015-12-02	4	Orwin John A	RLYP	Stock Option (right to buy)	M - Exercise	D	7.40		-20,000		757,877
2015-12-04	2015-12-02	4	Orwin John A	RLYP	Common Stock	S - Sale	D		25.0000	-20,000	-500		59,375
2015-12-04	2015-12-02	4	Orwin John A	RLYP	Common Stock	M - Exercise	D		7.4000	20,000	148		79,375
2015-11-10	2015-11-06	4	Krasnow Ronald A.	RLYP	Common Stock	A - Award	D			4,375			14,853
2015-11-10	2015-11-06	4	Harrison Stephen D	RLYP	Common Stock	A - Award	D			6,250			13,750
2015-11-10	2015-11-06	4	Corbett Mary	RLYP	Common Stock	A - Award	D			4,375			14,853
2015-11-10	2015-11-06	4	Stahl Wilhelm	RLYP	Common Stock	A - Award	D			4,375			14,853
2015-11-10	2015-11-06	4	BALL KRISTINE M	RLYP	Common Stock	A - Award	D			6,250			21,290
2015-11-10	2015-11-06	4	Garland J. Scott	RLYP	Common Stock	A - Award	D			6,250			13,750
2015-11-10	2015-11-06	4	Orwin John A	RLYP	Common Stock	A - Award	D			16,875			59,375
2015-11-10	2015-11-06	4	Berman Lance	RLYP	Common Stock	A - Award	D			6,250			21,290
2015-10-22	2015-10-22	4	ORBIMED ADVISORS LLC See Footnotes	RLYP	Common Stock	P - Purchase	I		12.9200	310,700	4,014		7,900,000
2015-10-22	2015-10-22	4	ORBIMED ADVISORS LLC See Footnotes	RLYP	Common Stock	P - Purchase	I		11.9700	189,300	2,266		7,589,300
2015-09-03	2015-09-02	4	BALL KRISTINE M	RLYP	Common Stock	S - Sale	D		22.9600	-646	-15		15,040
2015-08-19	2015-08-17	4	Krasnow Ronald A.	RLYP	Common Stock	S - Sale	D		24.7545	-522	-13		10,478
2015-08-19	2015-08-17	4	Corbett Mary	RLYP	Common Stock	S - Sale	D		24.7200	-1	-0		10,478
2015-08-19	2015-08-17	4	Corbett Mary	RLYP	Common Stock	S - Sale	D		24.7243	-521	-13		10,479
2015-08-19	2015-08-17	4	Berman Lance	RLYP	Common Stock	S - Sale	D		24.7693	-710	-18		15,040
2015-08-19	2015-08-17	4	Orwin John A	RLYP	Common Stock	S - Sale	D		25.0000	-2,366	-59		42,500
2015-08-19	2015-08-17	4	Orwin John A	RLYP	Common Stock	S - Sale	D		24.6900	-2,634	-65		44,866
2015-08-19	2015-08-17	4	Stahl Wilhelm	RLYP	Common Stock	S - Sale	D		24.7010	-522	-13		10,478
2015-08-19	2015-08-17	4	Lockey Claire	RLYP	Common Stock	S - Sale	D		24.6906	-522	-13		10,478
2015-08-19	2015-08-17	4	BALL KRISTINE M	RLYP	Common Stock	S - Sale	D		24.7845	-710	-18		15,040
2015-08-12	2015-08-10	4	Lockey Claire	RLYP	Stock Option (right to buy)	A - Award	D	28.38		24,500		24,500
2015-08-12	2015-08-10	4	Lockey Claire	RLYP	Common Stock	A - Award	D			5,500			11,000
2015-08-12	2015-08-10	4	Krasnow Ronald A.	RLYP	Stock Option (right to buy)	A - Award	D	28.38		24,500		24,500
2015-08-12	2015-08-10	4	Krasnow Ronald A.	RLYP	Common Stock	A - Award	D			5,500			11,000
2015-08-12	2015-08-10	4	Harrison Stephen D	RLYP	Stock Option (right to buy)	A - Award	D	28.38		35,000		35,000
2015-08-12	2015-08-10	4	Harrison Stephen D	RLYP	Common Stock	A - Award	D			7,500			7,500
2015-08-12	2015-08-10	4	Corbett Mary	RLYP	Stock Option (right to buy)	A - Award	D	28.38		24,500		24,500
2015-08-12	2015-08-10	4	Corbett Mary	RLYP	Common Stock	A - Award	D			5,500			11,000
2015-08-12	2015-08-10	4	Berman Lance	RLYP	Stock Option (right to buy)	A - Award	D	28.38		38,500		38,500
2015-08-12	2015-08-10	4	Berman Lance	RLYP	Common Stock	A - Award	D			8,250			15,750
2015-08-12	2015-08-10	4	Stahl Wilhelm	RLYP	Stock Option (right to buy)	A - Award	D	28.38		24,500		24,500
2015-08-12	2015-08-10	4	Stahl Wilhelm	RLYP	Common Stock	A - Award	D			5,500			11,000
2015-08-12	2015-08-10	4	BALL KRISTINE M	RLYP	Stock Option (right to buy)	A - Award	D	28.38		38,500		38,500
2015-08-12	2015-08-10	4	BALL KRISTINE M	RLYP	Common Stock	A - Award	D			8,250			15,750
2015-08-12	2015-08-10	4	Garland J. Scott	RLYP	Stock Option (right to buy)	A - Award	D	28.38		35,000		35,000
2015-08-12	2015-08-10	4	Garland J. Scott	RLYP	Common Stock	A - Award	D			7,500			7,500
2015-08-12	2015-08-10	4	Orwin John A	RLYP	Stock Option (right to buy)	A - Award	D	28.38		105,000		105,000
2015-08-12	2015-08-10	4	Orwin John A	RLYP	Common Stock	A - Award	D			22,500			47,500
2015-08-03	2015-07-31	4	Orwin John A	RLYP	Stock Option (right to buy)	M - Exercise	D	7.40		-5,000		777,877
2015-08-03	2015-07-31	4	Orwin John A	RLYP	Common Stock	S - Sale	D		34.1400	-200	-7		25,000
2015-08-03	2015-07-31	4	Orwin John A	RLYP	Common Stock	S - Sale	D		33.5099	-9,800	-328		25,200
2015-08-03	2015-07-31	4	Orwin John A	RLYP	Common Stock	M - Exercise	D		7.4000	5,000	37		35,000
2015-08-03	2015-07-30	4	Orwin John A	RLYP	Stock Option (right to buy)	M - Exercise	D	7.40		-20,000		782,877
2015-08-03	2015-07-30	4	Orwin John A	RLYP	Common Stock	S - Sale	D		34.1100	-200	-7		30,000
2015-08-03	2015-07-30	4	Orwin John A	RLYP	Common Stock	S - Sale	D		33.5733	-19,800	-665		30,200
2015-08-03	2015-07-30	4	Orwin John A	RLYP	Common Stock	M - Exercise	D		7.4000	20,000	148		50,000
2015-06-15	2015-06-11	4	HASTINGS PAUL J	RLYP	Common Stock	S - Sale	D		34.6349	-1,454	-50		3,508
2015-06-15	2015-06-11	4	MCGIRR DAVID W J	RLYP	Common Stock	S - Sale	D		34.6724	-1,220	-42		3,742
2015-06-15	2015-06-11	4	Schuetz Thomas J.	RLYP	Common Stock	S - Sale	D		34.5710	-1,000	-35		3,962
2015-06-15	2015-06-11	4	Butler John P.	RLYP	Common Stock	S - Sale	D		34.6241	-1,100	-38		3,862
2015-06-09	2015-06-04	4	MCGIRR DAVID W J	RLYP	Stock Option (right to buy)	A - Award	D	35.79		4,500		4,500
2015-06-09	2015-06-04	4	MCGIRR DAVID W J	RLYP	Common Stock	A - Award	D			2,250			4,962
2015-06-08	2015-06-04	4	HASTINGS PAUL J	RLYP	Stock Option (right to buy)	A - Award	D	35.79		4,500		4,500
2015-06-08	2015-06-04	4	HASTINGS PAUL J	RLYP	Common Stock	A - Award	D			2,250			4,962
2015-06-08	2015-06-04	4	SPIEGELMAN DANIEL K	RLYP	Stock Option (right to buy)	A - Award	D	35.79		4,500		4,500
2015-06-08	2015-06-04	4	SPIEGELMAN DANIEL K	RLYP	Common Stock	A - Award	D			2,250			2,250
2015-06-08	2015-06-04	4	Torley Helen	RLYP	Stock Option (right to buy)	A - Award	D	35.79		4,500		4,500
2015-06-08	2015-06-04	4	Torley Helen	RLYP	Common Stock	A - Award	D			2,250			2,250
2015-06-08	2015-06-04	4	Schuetz Thomas J.	RLYP	Stock Option (right to buy)	A - Award	D	35.79		4,500		4,500
2015-06-08	2015-06-04	4	Schuetz Thomas J.	RLYP	Common Stock	A - Award	D			2,250			4,962
2015-06-08	2015-06-04	4	Butler John P.	RLYP	Stock Option (right to buy)	A - Award	D	35.79		4,500		4,500
2015-06-08	2015-06-04	4	Butler John P.	RLYP	Common Stock	A - Award	D			2,250			4,962
2015-06-08	2015-06-04	4	Hillan Kenneth J.	RLYP	Stock Option (right to buy)	A - Award	D	35.79		4,500		4,500
2015-06-08	2015-06-04	4	Hillan Kenneth J.	RLYP	Common Stock	A - Award	D			2,250			2,250
2015-06-02	2015-06-01	4	Orwin John A	RLYP	Stock Option (right to buy)	M - Exercise	D	7.40		-8,555		802,877
2015-06-02	2015-06-01	4	Orwin John A	RLYP	Common Stock	S - Sale	D		36.9437	-5,204	-192		30,000
2015-06-02	2015-06-01	4	Orwin John A	RLYP	Common Stock	S - Sale	D		35.7913	-8,351	-299		35,204
2015-06-02	2015-06-01	4	Orwin John A	RLYP	Common Stock	M - Exercise	D		7.4000	8,555	63		43,555
2015-06-02	2015-05-29	4	Orwin John A	RLYP	Stock Option (right to buy)	M - Exercise	D	7.40		-20,000		811,432
2015-06-02	2015-05-29	4	Orwin John A	RLYP	Common Stock	S - Sale	D		36.9786	-5,306	-196		35,000
2015-06-02	2015-05-29	4	Orwin John A	RLYP	Common Stock	S - Sale	D		36.3953	-14,694	-535		40,306
2015-06-02	2015-05-29	4	Orwin John A	RLYP	Common Stock	M - Exercise	D		7.4000	20,000	148		55,000
2015-05-20	2015-05-18	4	ORBIMED ADVISORS LLC See Footnotes	RLYP	Common Stock	S - Sale	I		34.1300	-1,457,551	-49,746		7,400,000
2015-05-13	2015-05-11	4	VEITINGER KLAUS R DR	RLYP	Stock Option (right to buy)	M - Exercise	D	3.96		-5,834		69,543
2015-05-13	2015-05-11	4	VEITINGER KLAUS R DR	RLYP	Common Stock	S - Sale	D		36.0622	-5,834	-210		2,712
2015-05-13	2015-05-11	4	VEITINGER KLAUS R DR	RLYP	Common Stock	M - Exercise	D		3.9600	5,834	23		8,546
2015-04-13	2015-04-10	4	VEITINGER KLAUS R DR	RLYP	Stock Option (right to buy)	M - Exercise	D	3.96		-5,832		75,377
2015-04-13	2015-04-10	4	VEITINGER KLAUS R DR	RLYP	Common Stock	S - Sale	D		35.3530	-5,832	-206		2,712
2015-04-13	2015-04-10	4	VEITINGER KLAUS R DR	RLYP	Common Stock	M - Exercise	D		3.9600	5,832	23		8,544
2015-03-12	2015-03-10	4	VEITINGER KLAUS R DR	RLYP	Stock Option (right to buy)	M - Exercise	D	3.96		-2,503		81,209
2015-03-12	2015-03-10	4	VEITINGER KLAUS R DR	RLYP	Stock Option (right to buy)	M - Exercise	D	4.65		-3,331		12,795
2015-03-12	2015-03-10	4	VEITINGER KLAUS R DR	RLYP	Common Stock	S - Sale	D		38.6688	-5,834	-226		2,712
2015-03-12	2015-03-10	4	VEITINGER KLAUS R DR	RLYP	Common Stock	M - Exercise	D		3.9600	2,503	10		8,546
2015-03-12	2015-03-10	4	VEITINGER KLAUS R DR	RLYP	Common Stock	M - Exercise	D		4.6500	3,331	15		6,043
2015-03-06	2015-03-04	4	Lockey Claire	RLYP	Stock Option (right to buy)	M - Exercise	D	3.79		-948		25,214
2015-03-06	2015-03-04	4	Lockey Claire	RLYP	Stock Option (right to buy)	M - Exercise	D	4.65		-9,052		215
2015-03-06	2015-03-04	4	Lockey Claire	RLYP	Common Stock	S - Sale	D		40.0000	-10,000	-400		5,500
2015-03-06	2015-03-04	4	Lockey Claire	RLYP	Common Stock	M - Exercise	D		3.7900	948	4		15,500
2015-03-06	2015-03-04	4	Lockey Claire	RLYP	Common Stock	M - Exercise	D		4.6500	9,052	42		14,552
2015-03-05	2015-03-05	4	BALL KRISTINE M	RLYP	Stock Option (right to buy)	M - Exercise	D	3.96		-3,000		122,872
2015-03-05	2015-03-05	4	BALL KRISTINE M	RLYP	Common Stock	S - Sale	D		41.0000	-3,000	-123		7,500
2015-03-05	2015-03-05	4	BALL KRISTINE M	RLYP	Common Stock	M - Exercise	D		3.9600	3,000	12		10,500
2015-03-05	2015-03-03	4	BALL KRISTINE M	RLYP	Common Stock	S - Sale	D		38.8000	-519	-20		7,500
2015-02-27	2015-02-27	4	Krasnow Ronald A.	RLYP	Common Stock	S - Sale	D		39.0000	-348	-14		5,500
2015-02-27	2015-02-26	4	Krasnow Ronald A.	RLYP	Common Stock	S - Sale	D		39.0000	-5,000	-195		5,848
2015-02-27	2015-02-25	4	Krasnow Ronald A.	RLYP	Common Stock	S - Sale	D		39.0000	-5,000	-195		10,848
2015-02-25	2015-02-24	4	Krasnow Ronald A.	RLYP	Common Stock	S - Sale	D		39.0000	-5,000	-195		15,848
2015-02-25	2015-02-23	4	Krasnow Ronald A.	RLYP	Common Stock	S - Sale	D		39.0000	-5,000	-195		20,848
2015-02-25	2015-02-24	4	Berman Lance	RLYP	Stock Option (right to buy)	M - Exercise	D	7.40		-1,840		30,919
2015-02-25	2015-02-24	4	Berman Lance	RLYP	Stock Option (right to buy)	M - Exercise	D	3.96		-1,580		33,114
2015-02-25	2015-02-24	4	Berman Lance	RLYP	Stock Option (right to buy)	M - Exercise	D	3.96		-1,580		33,114
2015-02-25	2015-02-24	4	Berman Lance	RLYP	Common Stock	S - Sale	D		38.6274	-2,300	-89		7,500
2015-02-25	2015-02-24	4	Berman Lance	RLYP	Common Stock	S - Sale	D		37.8170	-2,700	-102		9,800
2015-02-25	2015-02-24	4	Berman Lance	RLYP	Common Stock	M - Exercise	D		7.4000	1,840	14		12,500
2015-02-25	2015-02-24	4	Berman Lance	RLYP	Common Stock	M - Exercise	D		3.9600	1,580	6		10,660
2015-02-25	2015-02-24	4	Berman Lance	RLYP	Common Stock	M - Exercise	D		3.9600	1,580	6		10,660
2015-02-10	2015-02-10	4	VEITINGER KLAUS R DR	RLYP	Stock Option (right to buy)	M - Exercise	D	4.65		-5,834		16,126
2015-02-10	2015-02-10	4	VEITINGER KLAUS R DR	RLYP	Common Stock	S - Sale	D		32.7400	-100	-3		2,712
2015-02-10	2015-02-10	4	VEITINGER KLAUS R DR	RLYP	Common Stock	S - Sale	D		32.1042	-5,734	-184		2,812
2015-02-10	2015-02-10	4	VEITINGER KLAUS R DR	RLYP	Common Stock	M - Exercise	D		4.6500	5,834	27		8,546
2015-01-26	2015-01-22	4	Torley Helen	RLYP	Stock Option (right to buy)	A - Award	D	36.83		12,000		12,000
2015-01-23	2015-01-21	4	Lockey Claire	RLYP	Stock Option (right to buy)	M - Exercise	D	4.65		-5,000		9,267
2015-01-23	2015-01-21	4	Lockey Claire	RLYP	Common Stock	S - Sale	D		35.0000	-5,000	-175		5,500
2015-01-23	2015-01-21	4	Lockey Claire	RLYP	Common Stock	M - Exercise	D		4.6500	5,000	23		10,500
2015-01-23	2015-01-21	4	Krasnow Ronald A.	RLYP	Stock Option (right to buy)	M - Exercise	D	3.96		-13,551		37,611
2015-01-23	2015-01-21	4	Krasnow Ronald A.	RLYP	Stock Option (right to buy)	M - Exercise	D	3.96		-33,368		8,783
2015-01-23	2015-01-21	4	Krasnow Ronald A.	RLYP	Stock Option (right to buy)	M - Exercise	D	2.76		-8,081		0
2015-01-23	2015-01-21	4	Krasnow Ronald A.	RLYP	Common Stock	S - Sale	D		35.0000	-55,000	-1,925		25,848
2015-01-23	2015-01-21	4	Krasnow Ronald A.	RLYP	Common Stock	M - Exercise	D		3.9600	13,551	54		80,848
2015-01-23	2015-01-21	4	Krasnow Ronald A.	RLYP	Common Stock	M - Exercise	D		3.9600	33,368	132		67,297
2015-01-23	2015-01-21	4	Krasnow Ronald A.	RLYP	Common Stock	M - Exercise	D		2.7600	8,081	22		33,929
2015-01-23	2015-01-21	4	BALL KRISTINE M	RLYP	Stock Option (right to buy)	M - Exercise	D	3.96		-3,000		125,872
2015-01-23	2015-01-21	4	BALL KRISTINE M	RLYP	Common Stock	S - Sale	D		36.0000	-3,000	-108		7,500
2015-01-23	2015-01-21	4	BALL KRISTINE M	RLYP	Common Stock	M - Exercise	D		3.9600	3,000	12		10,500
2015-01-16	2015-01-14	4	Krasnow Ronald A.	RLYP	Stock Option (right to buy)	M - Exercise	D	2.76		-5,000		8,081
2015-01-16	2015-01-14	4	Krasnow Ronald A.	RLYP	Common Stock	S - Sale	D		34.0939	-1,080	-37		25,848
2015-01-16	2015-01-14	4	Krasnow Ronald A.	RLYP	Common Stock	S - Sale	D		33.4371	-3,920	-131		26,928
2015-01-16	2015-01-14	4	Krasnow Ronald A.	RLYP	Common Stock	M - Exercise	D		2.7600	5,000	14		30,848
2015-01-14	2015-01-12	4	VEITINGER KLAUS R DR	RLYP	Stock Option (right to buy)	M - Exercise	D	4.65		-5,834		21,960
2015-01-14	2015-01-12	4	VEITINGER KLAUS R DR	RLYP	Common Stock	S - Sale	D		32.7922	-1,448	-47		2,712
2015-01-14	2015-01-12	4	VEITINGER KLAUS R DR	RLYP	Common Stock	S - Sale	D		32.1718	-4,386	-141		4,160
2015-01-14	2015-01-12	4	VEITINGER KLAUS R DR	RLYP	Common Stock	M - Exercise	D		4.6500	5,834	27		8,546
2015-01-06	2015-01-02	4	Harrison Stephen D	RLYP	Stock Option (Right to Buy)	A - Award	D	30.80		75,000		75,000
2014-12-12	2014-12-12	4	VEITINGER KLAUS R DR	RLYP	Stock Option (right to buy)	M - Exercise	D	4.65		-9,852		27,794
2014-12-12	2014-12-12	4	VEITINGER KLAUS R DR	RLYP	Common Stock	S - Sale	D		32.5000	-9,852	-320		2,712
2014-12-12	2014-12-12	4	VEITINGER KLAUS R DR	RLYP	Common Stock	M - Exercise	D		4.6500	9,852	46		12,564
2014-12-12	2014-12-11	4	VEITINGER KLAUS R DR	RLYP	Stock Option (right to buy)	M - Exercise	D	4.65		-150		37,646
2014-12-12	2014-12-11	4	VEITINGER KLAUS R DR	RLYP	Common Stock	S - Sale	D		32.5000	-150	-5		2,712
2014-12-12	2014-12-11	4	VEITINGER KLAUS R DR	RLYP	Common Stock	M - Exercise	D		4.6500	150	1		2,862
2014-12-12	2014-12-10	4	VEITINGER KLAUS R DR	RLYP	Stock Option (right to buy)	M - Exercise	D	4.65		-4,167		37,796
2014-12-12	2014-12-10	4	VEITINGER KLAUS R DR	RLYP	Common Stock	S - Sale	D		32.1990	-263	-8		2,712
2014-12-12	2014-12-10	4	VEITINGER KLAUS R DR	RLYP	Common Stock	S - Sale	D		31.5211	-3,104	-98		2,975
2014-12-12	2014-12-10	4	VEITINGER KLAUS R DR	RLYP	Common Stock	S - Sale	D		30.3838	-800	-24		6,079
2014-12-12	2014-12-10	4	VEITINGER KLAUS R DR	RLYP	Common Stock	M - Exercise	D		4.6500	4,167	19		6,879
2014-12-11	2014-12-09	4	5AM Partners III, LLC See footnotes	RLYP	Common Stock	S - Sale	I		30.0400	-14,814	-445		47,502
2014-12-11	2014-12-09	4	5AM Partners III, LLC See footnotes	RLYP	Common Stock	S - Sale	I		30.0400	-574,823	-17,268		1,843,243
2014-12-10	2014-12-09	4	Lockey Claire	RLYP	Stock Option (right to buy)	M - Exercise	D	4.65		-8,000		14,267
2014-12-10	2014-12-09	4	Lockey Claire	RLYP	Common Stock	S - Sale	D		30.0000	-8,000	-240		5,500
2014-12-10	2014-12-09	4	Lockey Claire	RLYP	Common Stock	M - Exercise	D		4.6500	8,000	37		13,500
2014-12-02	2014-11-28	4	Berman Lance	RLYP	Stock Option (right to buy)	M - Exercise	D	7.40		-786		32,759
2014-12-02	2014-11-28	4	Berman Lance	RLYP	Stock Option (right to buy)	M - Exercise	D	3.96		-2,107		34,694
2014-12-02	2014-11-28	4	Berman Lance	RLYP	Stock Option (right to buy)	M - Exercise	D	3.96		-2,107		34,694
2014-12-02	2014-11-28	4	Berman Lance	RLYP	Common Stock	S - Sale	D		25.0000	-5,000	-125		7,500
2014-12-02	2014-11-28	4	Berman Lance	RLYP	Common Stock	M - Exercise	D		7.4000	786	6		12,500
2014-12-02	2014-11-28	4	Berman Lance	RLYP	Common Stock	M - Exercise	D		3.9600	2,107	8		11,714
2014-12-02	2014-11-28	4	Berman Lance	RLYP	Common Stock	M - Exercise	D		3.9600	2,107	8		11,714
2014-11-26	2014-11-25	4	Berman Lance	RLYP	Stock Option (Right to Buy)	M - Exercise	D	7.40		-2,616		33,545
2014-11-26	2014-11-25	4	Berman Lance	RLYP	Stock Option (Right to Buy)	M - Exercise	D	3.96		-11,585		36,801
2014-11-26	2014-11-25	4	Berman Lance	RLYP	Stock Option (right to buy)	M - Exercise	D	3.96		-799		28,251
2014-11-26	2014-11-25	4	Berman Lance	RLYP	Common Stock	S - Sale	D		25.0000	-15,000	-375		7,500
2014-11-26	2014-11-25	4	Berman Lance	RLYP	Common Stock	M - Exercise	D		7.4000	2,616	19		22,500
2014-11-26	2014-11-25	4	Berman Lance	RLYP	Common Stock	M - Exercise	D		3.9600	11,585	46		19,884
2014-11-26	2014-11-25	4	Berman Lance	RLYP	Common Stock	M - Exercise	D		3.9600	799	3		8,299
2014-11-26	2014-11-24	4	Berman Lance	RLYP	Stock Option (right to buy)	M - Exercise	D	3.96		-15,000		29,050
2014-11-26	2014-11-24	4	Berman Lance	RLYP	Common Stock	S - Sale	D		25.0000	-15,000	-375		7,500
2014-11-26	2014-11-24	4	Berman Lance	RLYP	Common Stock	M - Exercise	D		3.9600	15,000	59		22,500
2014-11-24	2014-11-20	4	VEITINGER KLAUS R DR	RLYP	Stock Option (right to buy)	M - Exercise	D	4.65		-3,334		41,963
2014-11-24	2014-11-20	4	VEITINGER KLAUS R DR	RLYP	Common Stock	S - Sale	D		22.5000	-3,334	-75		2,712
2014-11-24	2014-11-20	4	VEITINGER KLAUS R DR	RLYP	Common Stock	M - Exercise	D		4.6500	3,334	16		6,046
2014-11-18	2014-11-17	4	Garland J. Scott	RLYP	Stock Option (right to buy)	A - Award	D	21.36		100,000		100,000
2014-11-12	2014-11-10	4	VEITINGER KLAUS R DR	RLYP	Stock Option (right to buy)	M - Exercise	D	4.65		-2,500		45,297
2014-11-12	2014-11-10	4	VEITINGER KLAUS R DR	RLYP	Common Stock	S - Sale	D		20.0576	-2,500	-50		2,712
2014-11-12	2014-11-10	4	VEITINGER KLAUS R DR	RLYP	Common Stock	M - Exercise	D		4.6500	2,500	12		5,212
2014-10-15	2014-10-10	4	VEITINGER KLAUS R DR	RLYP	Stock Option (right to buy)	M - Exercise	D	4.65		-2,500		47,797
2014-10-15	2014-10-10	4	VEITINGER KLAUS R DR	RLYP	Common Stock	S - Sale	D		19.8600	-100	-2		2,712
2014-10-15	2014-10-10	4	VEITINGER KLAUS R DR	RLYP	Common Stock	S - Sale	D		19.3155	-2,400	-46		2,812
2014-10-15	2014-10-10	4	VEITINGER KLAUS R DR	RLYP	Common Stock	M - Exercise	D		4.6500	2,500	12		5,212
2014-09-25	2014-09-24	4	Berman Lance	RLYP	Stock Option (right to buy)	M - Exercise	D	7.40		-649		36,161
2014-09-25	2014-09-24	4	Berman Lance	RLYP	Stock Option (right to buy)	M - Exercise	D	3.96		-1,848		48,386
2014-09-25	2014-09-24	4	Berman Lance	RLYP	Stock Option (right to buy)	M - Exercise	D	3.96		-2,503		44,050
2014-09-25	2014-09-24	4	Berman Lance	RLYP	Common Stock	S - Sale	D		22.0000	-5,000	-110		7,500
2014-09-25	2014-09-24	4	Berman Lance	RLYP	Common Stock	M - Exercise	D		7.4000	649	5		12,500
2014-09-25	2014-09-24	4	Berman Lance	RLYP	Common Stock	M - Exercise	D		3.9600	1,848	7		11,851
2014-09-25	2014-09-24	4	Berman Lance	RLYP	Common Stock	M - Exercise	D		3.9600	2,503	10		10,003
2014-09-18	2014-09-17	4	ORBIMED ADVISORS LLC See footnotes	RLYP	Common Stock	S - Sale	I		25.0700	-49,000	-1,228		8,857,551
2014-09-18	2014-09-16	4	ORBIMED ADVISORS LLC See footnotes	RLYP	Common Stock	S - Sale	I		26.0600	-2,600	-68		8,906,551
2014-09-18	2014-09-16	4	ORBIMED ADVISORS LLC See footnotes	RLYP	Common Stock	S - Sale	I		25.4500	-42,400	-1,079		8,909,151
2014-09-17	2014-09-16	4	5AM Partners II, LLC See Footnotes	RLYP	Common Stock	S - Sale	I		26.0300	-23,252	-605		50,082
2014-09-17	2014-09-16	4	5AM Partners II, LLC See Footnotes	RLYP	Common Stock	S - Sale	I		26.0300	-589,288	-15,339		1,269,398
2014-09-11	2014-09-10	4	VEITINGER KLAUS R DR	RLYP	Stock Option (right to buy)	M - Exercise	D	4.65		-4,167		50,297
2014-09-11	2014-09-10	4	VEITINGER KLAUS R DR	RLYP	Common Stock	S - Sale	D		23.0024	-4,167	-96		2,712
2014-09-11	2014-09-10	4	VEITINGER KLAUS R DR	RLYP	Common Stock	M - Exercise	D		4.6500	4,167	19		6,879
2014-09-03	2014-08-29	4	Stahl Wilhelm	RLYP	Stock Option (Right to Buy)	M - Exercise	D	4.65		-5,813		0
2014-09-03	2014-08-29	4	Stahl Wilhelm	RLYP	Stock Option (Right to Buy)	M - Exercise	D	3.96		-9,972		50,306
2014-09-03	2014-08-29	4	Stahl Wilhelm	RLYP	Common Stock	S - Sale	D		25.2932	-15,785	-399		5,500
2014-09-03	2014-08-29	4	Stahl Wilhelm	RLYP	Common Stock	M - Exercise	D		4.6500	5,813	27		21,285
2014-09-03	2014-08-29	4	Stahl Wilhelm	RLYP	Common Stock	M - Exercise	D		3.9600	9,972	39		15,472
2014-08-27	2014-08-26	4	5AM Partners II, LLC See footnotes	RLYP	Common Stock	S - Sale	I		26.5300	-3,656	-97		73,334
2014-08-27	2014-08-26	4	5AM Partners II, LLC See footnotes	RLYP	Common Stock	S - Sale	I		26.5300	-92,654	-2,458		1,858,686
2014-08-27	2014-08-25	4	5AM Partners II, LLC See footnotes	RLYP	Common Stock	S - Sale	I		26.5000	-12,781	-339		76,990
2014-08-27	2014-08-25	4	5AM Partners II, LLC See footnotes	RLYP	Common Stock	S - Sale	I		26.5000	-323,909	-8,584		1,951,340
2014-08-26	2014-08-25	4	Berman Lance	RLYP	Stock Option (Right to Buy)	M - Exercise	D	7.40		-5,000		36,810
2014-08-26	2014-08-25	4	Berman Lance	RLYP	Common Stock	S - Sale	D		26.4758	-5,000	-132		7,500
2014-08-26	2014-08-25	4	Berman Lance	RLYP	Common Stock	M - Exercise	D		7.4000	5,000	37		12,500
2014-08-26	2014-08-22	4	Berman Lance	RLYP	Stock Option (Right to Buy)	M - Exercise	D	7.40		-1,793		41,810
2014-08-26	2014-08-22	4	Berman Lance	RLYP	Stock Option (Right to Buy)	M - Exercise	D	3.96		-13,207		56,438
2014-08-26	2014-08-22	4	Berman Lance	RLYP	Common Stock	S - Sale	D		25.6895	-15,000	-385		7,500
2014-08-26	2014-08-22	4	Berman Lance	RLYP	Common Stock	M - Exercise	D		7.4000	1,793	13		22,500
2014-08-26	2014-08-22	4	Berman Lance	RLYP	Common Stock	M - Exercise	D		3.9600	13,207	52		20,707
2014-08-19	2014-08-15	4	ORBIMED ADVISORS LLC See footnotes	RLYP	Common Stock	S - Sale	I		26.3500	-990,000	-26,086		8,951,551
2014-08-18	2014-08-14	4	BALL KRISTINE M	RLYP	Stock Option (right to buy)	A - Award	D	27.21		35,000		35,000
2014-08-18	2014-08-14	4	BALL KRISTINE M	RLYP	Common Stock	A - Award	D			7,500			7,500
2014-08-18	2014-08-14	4	Berman Lance	RLYP	Stock Option (right to buy)	A - Award	D	27.21		35,000		35,000
2014-08-18	2014-08-14	4	Berman Lance	RLYP	Common Stock	A - Award	D			7,500			7,500
2014-08-18	2014-08-14	4	Orwin John A	RLYP	Stock Option (right to buy)	A - Award	D	27.21		94,500		94,500
2014-08-18	2014-08-14	4	Orwin John A	RLYP	Common Stock	A - Award	D			20,000			35,000
2014-08-18	2014-08-14	4	Lockey Claire	RLYP	Stock Option (right to buy)	A - Award	D	27.21		24,500		24,500
2014-08-18	2014-08-14	4	Lockey Claire	RLYP	Common Stock	A - Award	D			5,500			5,500
2014-08-18	2014-08-14	4	Stahl Wilhelm	RLYP	Stock Option (right to buy)	A - Award	D	27.21		24,500		24,500
2014-08-18	2014-08-14	4	Stahl Wilhelm	RLYP	Common Stock	A - Award	D			5,500			5,500
2014-08-18	2014-08-14	4	Krasnow Ronald A.	RLYP	Stock Option (right to buy)	A - Award	D	27.21		24,500		24,500
2014-08-18	2014-08-14	4	Krasnow Ronald A.	RLYP	Common Stock	A - Award	D			5,500			25,848
2014-08-18	2014-08-14	4	Corbett Mary	RLYP	Stock Option (right to buy)	A - Award	D	27.21		24,500		24,500
2014-08-18	2014-08-14	4	Corbett Mary	RLYP	Common Stock	A - Award	D			5,500			5,500
2014-08-12	2014-08-11	4	VEITINGER KLAUS R DR	RLYP	Stock Option (right to buy)	M - Exercise	D	4.65		-4,167		54,464
2014-08-12	2014-08-11	4	VEITINGER KLAUS R DR	RLYP	Common Stock	S - Sale	D		27.7330	-4,167	-116		2,712
2014-08-12	2014-08-11	4	VEITINGER KLAUS R DR	RLYP	Common Stock	M - Exercise	D		4.6500	4,167	19		6,879
2014-08-12	2014-08-08	4	Lockey Claire	RLYP	Stock Option (right to buy)	M - Exercise	D	4.65		-10,000		22,267
2014-08-12	2014-08-08	4	Lockey Claire	RLYP	Common Stock	S - Sale	D		27.5000	-6,000	-165		0
2014-08-12	2014-08-08	4	Lockey Claire	RLYP	Common Stock	S - Sale	D		25.0000	-4,000	-100		6,000
2014-08-12	2014-08-08	4	Lockey Claire	RLYP	Common Stock	M - Exercise	D		4.6500	10,000	46		10,000
2014-08-12	2014-08-08	4	Stahl Wilhelm	RLYP	Stock Option (right to buy)	M - Exercise	D	3.96		-8,001		60,278
2014-08-12	2014-08-08	4	Stahl Wilhelm	RLYP	Stock Option (right to buy)	M - Exercise	D	3.96		-41,299		44,050
2014-08-12	2014-08-08	4	Stahl Wilhelm	RLYP	Common Stock	S - Sale	D		25.0930	-49,300	-1,237		0
2014-08-12	2014-08-08	4	Stahl Wilhelm	RLYP	Common Stock	M - Exercise	D		3.9600	8,001	32		49,300
2014-08-12	2014-08-08	4	Stahl Wilhelm	RLYP	Common Stock	M - Exercise	D		3.9600	41,299	164		41,299
2014-07-24	2014-07-24	4	Berman Lance	RLYP	Stock Option (right to buy)	M - Exercise	D	3.96		-6,204		63,441
2014-07-24	2014-07-24	4	Berman Lance	RLYP	Stock Option (right to buy)	M - Exercise	D	3.96		-8,796		46,553
2014-07-24	2014-07-24	4	Berman Lance	RLYP	Common Stock	S - Sale	D		24.5859	-1,472	-36		0
2014-07-24	2014-07-24	4	Berman Lance	RLYP	Common Stock	S - Sale	D		23.7807	-13,528	-322		1,472
2014-07-24	2014-07-24	4	Berman Lance	RLYP	Common Stock	M - Exercise	D		3.9600	6,204	25		15,000
2014-07-24	2014-07-24	4	Berman Lance	RLYP	Common Stock	M - Exercise	D		3.9600	8,796	35		8,796
2014-07-24	2014-07-23	4	Berman Lance	RLYP	Stock Option (right to buy)	M - Exercise	D	3.96		-15,000		55,349
2014-07-24	2014-07-23	4	Berman Lance	RLYP	Common Stock	S - Sale	D		24.6738	-400	-10		0
2014-07-24	2014-07-23	4	Berman Lance	RLYP	Common Stock	S - Sale	D		24.2296	-14,600	-354		400
2014-07-24	2014-07-23	4	Berman Lance	RLYP	Common Stock	M - Exercise	D		3.9600	15,000	59		15,000
2014-07-24	2014-07-22	4	Berman Lance	RLYP	Stock Option (right to buy)	M - Exercise	D	3.96		-15,000		70,349
2014-07-24	2014-07-22	4	Berman Lance	RLYP	Common Stock	S - Sale	D		23.6662	-15,000	-355		0
2014-07-24	2014-07-22	4	Berman Lance	RLYP	Common Stock	M - Exercise	D		3.9600	15,000	59		15,000
2014-07-11	2014-07-10	4	VEITINGER KLAUS R DR	RLYP	Stock Option (right to buy)	M - Exercise	D	4.65		-4,167		58,631
2014-07-11	2014-07-10	4	VEITINGER KLAUS R DR	RLYP	Common Stock	S - Sale	D		23.1232	-4,167	-96		2,712
2014-07-11	2014-07-10	4	VEITINGER KLAUS R DR	RLYP	Common Stock	M - Exercise	D		4.6500	4,167	19		6,879
2014-06-23	2014-06-19	4	SPIEGELMAN DANIEL K	RLYP	Stock Option (right to buy)	A - Award	D	23.96		12,000		12,000
2014-06-23	2014-06-19	4	HASTINGS PAUL J	RLYP	Stock Option (right to buy)	A - Award	D	23.96		3,828		3,828
2014-06-23	2014-06-19	4	HASTINGS PAUL J	RLYP	Common Stock	A - Award	D			2,712			2,712
2014-06-23	2014-06-19	4	MCGIRR DAVID W J	RLYP	Stock Option (right to buy)	A - Award	D	23.96		3,828		3,828
2014-06-23	2014-06-19	4	MCGIRR DAVID W J	RLYP	Common Stock	A - Award	D			2,712			2,712
2014-06-23	2014-06-19	4	VEITINGER KLAUS R DR	RLYP	Stock Option (right to buy)	A - Award	D	23.96		3,828		3,828
2014-06-23	2014-06-19	4	VEITINGER KLAUS R DR	RLYP	Common Stock	A - Award	D			2,712			2,712
2014-06-23	2014-06-19	4	Schuetz Thomas J.	RLYP	Stock Option (right to buy)	A - Award	D	23.96		3,828		3,828
2014-06-23	2014-06-19	4	Schuetz Thomas J.	RLYP	Common Stock	A - Award	D			2,712			2,712
2014-06-23	2014-06-19	4	Butler John P.	RLYP	Stock Option (right to buy)	A - Award	D	23.96		3,828		3,828
2014-06-23	2014-06-19	4	Butler John P.	RLYP	Common Stock	A - Award	D			2,712			2,712
2014-06-23	2014-06-19	4	Hillan Kenneth J.	RLYP	Stock Option (right to buy)	A - Award	D	23.96		12,000		12,000
2014-02-03	2014-01-30	4	Corbett Mary	RLYP	Stock Option (right to buy)	A - Award	D	33.76		50,000		50,000
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Warrant to Purchase Preferred Stock	J - Other	I	0.17		-676		0
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Warrant to Purchase Common Stock	M - Exercise	I	0.17		-2,931		0
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Warrant to Purchase Common Stock	J - Other	I	0.17		2,931		2,931
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Warrant to Purchase Preferred Stock	J - Other	I	0.17		-2,931		0
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Warrant to Purchase Common Stock	M - Exercise	I	9.18		-1,461		0
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Warrant to Purchase Common Stock	J - Other	I	9.18		1,461		1,461
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Warrant to Purchase Preferred Stock	J - Other	I	13.50		-994		0
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Warrant to Purchase Common Stock	M - Exercise	I	0.17		-17,141		0
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Warrant to Purchase Common Stock	J - Other	I	0.17		17,141		17,141
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Warrant to Purchase Preferred Stock	J - Other	I	0.17		-17,141		0
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Warrant to Purchase Common Stock	M - Exercise	I	0.17		-74,281		0
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Warrant to Purchase Common Stock	J - Other	I	0.17		74,281		74,281
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Warrant to Purchase Preferred Stock	J - Other	I	0.17		-74,281		0
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Warrant to Purchase Common Stock	M - Exercise	I	9.18		-37,056		0
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Warrant to Purchase Common Stock	J - Other	I	9.18		37,056		37,056
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Warrant to Purchase Preferred Stock	J - Other	I	13.50		-25,208		0
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Series C-2 Preferred Stock	C - Conversion	I			-7,340		0
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Series C-1 Preferred Stock	C - Conversion	I			-31,809		0
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Series C-2 Preferred Stock	C - Conversion	I			-284,822		0
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Series C-1 Preferred Stock	C - Conversion	I			-1,234,230		0
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Series C-2 Preferred Stock	C - Conversion	I			-1,888		0
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Series C-1 Preferred Stock	C - Conversion	I			-8,181		0
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Series B-2 Preferred Stock	C - Conversion	I			-22,765		0
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Series B-1 Preferred Stock	C - Conversion	I			-15,260		0
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Series A-1 Preferred Stock	C - Conversion	I			-29,876		0
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Series C-2 Preferred Stock	C - Conversion	I			-47,849		0
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Series C-1 Preferred Stock	C - Conversion	I			-207,347		0
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Series B-2 Preferred Stock	C - Conversion	I			-576,958		0
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Series B-1 Preferred Stock	C - Conversion	I			-386,754		0
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Series A-1 Preferred Stock	C - Conversion	I			-757,187		0
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Common Stock	C - Conversion	I			31,809			31,809
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Common Stock	P - Purchase	I		11.0000	363,328	3,997		2,418,066
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Common Stock	F - Taxes	I		11.0000	-1,596	-18		2,054,738
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Common Stock	M - Exercise	I		0.1700	102,036	17		2,056,334
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Common Stock	F - Taxes	I		11.0000	-6,914	-76		1,954,298
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Common Stock	M - Exercise	I		0.1700	442,160	75		1,961,212
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Common Stock	C - Conversion	I			284,822			1,519,052
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Common Stock	C - Conversion	I			1,234,230			1,234,230
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Common Stock	F - Taxes	I		11.0000	-11	-0		89,771
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Common Stock	M - Exercise	I		0.1700	676	0		89,782
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Common Stock	F - Taxes	I		11.0000	-46	-1		89,106
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Common Stock	M - Exercise	I		0.1700	2,931	0		89,152
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Common Stock	F - Taxes	I		11.0000	-1,220	-13		86,221
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Common Stock	M - Exercise	I		9.1848	1,461	13		87,441
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Common Stock	C - Conversion	I			1,888			85,980
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Common Stock	C - Conversion	I			8,181			84,092
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Common Stock	C - Conversion	I			22,765			75,911
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Common Stock	C - Conversion	I			22,432			53,146
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Common Stock	C - Conversion	I			29,876			30,714
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Common Stock	F - Taxes	I		11.0000	-269	-3		2,275,248
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Common Stock	M - Exercise	I		0.1700	17,141	3		2,275,517
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Common Stock	F - Taxes	I		11.0000	-1,162	-13		2,258,376
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Common Stock	M - Exercise	I		0.1700	74,281	13		2,259,538
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Common Stock	F - Taxes	I		11.0000	-30,942	-340		2,185,257
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Common Stock	M - Exercise	I		9.1848	37,056	340		2,216,199
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Common Stock	C - Conversion	I			47,849			2,179,143
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Common Stock	C - Conversion	I			207,347			2,131,294
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Common Stock	C - Conversion	I			576,958			1,923,947
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Common Stock	C - Conversion	I			568,542			1,346,989
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Common Stock	C - Conversion	I			757,187			778,447
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Warrant to Purchase Common Stock	M - Exercise	I	0.17		-2,629		0
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Warrant to Purchase Common Stock	J - Other	I	0.17		2,629		2,629
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Warrant to Purchase Preferred Stock	J - Other	I	0.17		-2,629		0
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Warrant to Purchase Common Stock	M - Exercise	I	0.17		-11,395		0
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Warrant to Purchase Common Stock	J - Other	I	0.17		11,395		11,395
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Warrant to Purchase Preferred Stock	J - Other	I	0.17		-11,395		0
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Warrant to Purchase Common Stock	M - Exercise	I	0.17		-102,036		0
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Warrant to Purchase Common Stock	J - Other	I	0.17		102,036		102,036
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Warrant to Purchase Preferred Stock	J - Other	I	0.17		-102,036		0
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Warrant to Purchase Common Stock	M - Exercise	I	0.17		-442,160		0
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Warrant to Purchase Common Stock	J - Other	I	0.17		442,160		442,160
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Warrant to Purchase Preferred Stock	J - Other	I	0.17		-442,160		0
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Warrant to Purchase Common Stock	M - Exercise	I	0.17		-676		0
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Warrant to Purchase Common Stock	J - Other	I	0.17		676		676
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Common Stock	P - Purchase	I		11.0000	9,364	103		62,316
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Common Stock	F - Taxes	I		11.0000	-42	-0		52,952
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Common Stock	M - Exercise	I		0.1700	2,629	0		52,994
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Common Stock	F - Taxes	I		11.0000	-179	-2		50,365
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Common Stock	M - Exercise	I		0.1700	11,395	2		50,544
2013-11-20	2013-11-20	4	ROCKLAGE SCOTT M See Footnotes	RLYP	Common Stock	C - Conversion	I			7,340			39,149
2013-11-20	2013-11-20	4	SILVERSTEIN JONATHAN See Footnotes	RLYP	Warrant to Purchase Common Stock	M - Exercise	I	0.17		-327,133		0
2013-11-20	2013-11-20	4	SILVERSTEIN JONATHAN See Footnotes	RLYP	Warrant to Purchase Common Stock	J - Other	I	0.17		327,133		327,133
2013-11-20	2013-11-20	4	SILVERSTEIN JONATHAN See Footnotes	RLYP	Warrant to Purchase Preferred Stock	J - Other	I	0.17		-327,133		0
2013-11-20	2013-11-20	4	SILVERSTEIN JONATHAN See Footnotes	RLYP	Warrant to Purchase Common Stock	M - Exercise	I	0.17		-1,417,578		0
2013-11-20	2013-11-20	4	SILVERSTEIN JONATHAN See Footnotes	RLYP	Warrant to Purchase Common Stock	J - Other	I	0.17		1,417,578		1,417,578
2013-11-20	2013-11-20	4	SILVERSTEIN JONATHAN See Footnotes	RLYP	Warrant to Purchase Preferred Stock	J - Other	I	0.17		-1,417,578		0
2013-11-20	2013-11-20	4	SILVERSTEIN JONATHAN See Footnotes	RLYP	Series C-2 Preferred Stock	C - Conversion	I			-693,991		0
2013-11-20	2013-11-20	4	SILVERSTEIN JONATHAN See Footnotes	RLYP	Series C-1 Preferred Stock	C - Conversion	I			-3,007,297		0
2013-11-20	2013-11-20	4	SILVERSTEIN JONATHAN See Footnotes	RLYP	Series B-2 Preferred Stock	C - Conversion	I			-1,905,702		0
2013-11-20	2013-11-20	4	SILVERSTEIN JONATHAN See Footnotes	RLYP	Series B-1 Preferred Stock	C - Conversion	I			-1,295,845		0
2013-11-20	2013-11-20	4	SILVERSTEIN JONATHAN See Footnotes	RLYP	Common Stock	P - Purchase	I		11.0000	712,192	7,834		9,941,551
2013-11-20	2013-11-20	4	SILVERSTEIN JONATHAN See Footnotes	RLYP	Common Stock	F - Taxes	I		11.0000	-5,116	-56		9,229,359
2013-11-20	2013-11-20	4	SILVERSTEIN JONATHAN See Footnotes	RLYP	Common Stock	M - Exercise	I		0.1700	327,133	56		9,234,475
2013-11-20	2013-11-20	4	SILVERSTEIN JONATHAN See Footnotes	RLYP	Common Stock	F - Taxes	I		11.0000	-22,166	-244		8,907,342
2013-11-20	2013-11-20	4	SILVERSTEIN JONATHAN See Footnotes	RLYP	Common Stock	M - Exercise	I		0.1700	1,417,578	241		8,929,508
2013-11-20	2013-11-20	4	SILVERSTEIN JONATHAN See Footnotes	RLYP	Common Stock	C - Conversion	I			693,991			7,511,930
2013-11-20	2013-11-20	4	SILVERSTEIN JONATHAN See Footnotes	RLYP	Common Stock	C - Conversion	I			3,007,297			6,817,939
2013-11-20	2013-11-20	4	SILVERSTEIN JONATHAN See Footnotes	RLYP	Common Stock	C - Conversion	I			1,905,702			3,810,642
2013-11-20	2013-11-20	4	SILVERSTEIN JONATHAN See Footnotes	RLYP	Common Stock	C - Conversion	I			1,904,940			1,904,940
2013-11-20	2013-11-20	4	HUNT RONALD	RLYP	Warrant to Purchase Common Stock	M - Exercise	I	9.18		-25,977		0
2013-11-20	2013-11-20	4	HUNT RONALD	RLYP	Warrant to Purchase Common Stock	J - Other	I	9.18		25,977		25,977
2013-11-20	2013-11-20	4	HUNT RONALD	RLYP	Warrant to Purchase Preferred Stock	J - Other	I	13.50		-17,671		0
2013-11-20	2013-11-20	4	HUNT RONALD	RLYP	Series C-2 Preferred Stock	C - Conversion	I			-125,067		0
2013-11-20	2013-11-20	4	HUNT RONALD	RLYP	Series C-1 Preferred Stock	C - Conversion	I			-541,960		0
2013-11-20	2013-11-20	4	HUNT RONALD	RLYP	Series B-2 Preferred Stock	C - Conversion	I			-378,773		0
2013-11-20	2013-11-20	4	HUNT RONALD	RLYP	Series B-1 Preferred Stock	C - Conversion	I			-259,676		0
2013-11-20	2013-11-20	4	HUNT RONALD	RLYP	Series A-1 Preferred Stock	C - Conversion	I			-497,093		0
2013-11-20	2013-11-20	4	HUNT RONALD	RLYP	Common Stock	P - Purchase	I		11.0000	185,978	2,046		2,114,890
2013-11-20	2013-11-20	4	HUNT RONALD	RLYP	Common Stock	F - Taxes	I		11.0000	-21,691	-239		1,928,912
2013-11-20	2013-11-20	4	HUNT RONALD	RLYP	Common Stock	M - Exercise	I		9.1848	25,977	239		1,950,603
2013-11-20	2013-11-20	4	HUNT RONALD	RLYP	Common Stock	C - Conversion	I			125,067			1,924,626
2013-11-20	2013-11-20	4	HUNT RONALD	RLYP	Common Stock	C - Conversion	I			541,960			1,799,559
2013-11-20	2013-11-20	4	HUNT RONALD	RLYP	Common Stock	C - Conversion	I			378,773			1,257,599
2013-11-20	2013-11-20	4	HUNT RONALD	RLYP	Common Stock	C - Conversion	I			381,733			878,826
2013-11-20	2013-11-20	4	HUNT RONALD	RLYP	Common Stock	C - Conversion	I			497,093			497,093
2013-11-20	2013-11-20	4	Orwin John A	RLYP	Common Stock	P - Purchase	D		11.0000	15,000	165		15,000
2013-11-20	2013-11-20	4	ORBIMED ADVISORS LLC See footnotes	RLYP	Warrant to Purchase Common Stock	M - Exercise	I	0.17		-327,133		0
2013-11-20	2013-11-20	4	ORBIMED ADVISORS LLC See footnotes	RLYP	Warrant to Purchase Common Stock	J - Other	I	0.17		327,133		327,133
2013-11-20	2013-11-20	4	ORBIMED ADVISORS LLC See footnotes	RLYP	Warrant to Purchase Preferred Stock	J - Other	I	0.17		-327,133		0
2013-11-20	2013-11-20	4	ORBIMED ADVISORS LLC See footnotes	RLYP	Warrant to Purchase Common Stock	M - Exercise	I	0.17		-1,417,578		0
2013-11-20	2013-11-20	4	ORBIMED ADVISORS LLC See footnotes	RLYP	Warrant to Purchase Common Stock	J - Other	I	0.17		1,417,578		1,417,578
2013-11-20	2013-11-20	4	ORBIMED ADVISORS LLC See footnotes	RLYP	Warrant to Purchase Preferred Stock	J - Other	I	0.17		-1,417,578		0
2013-11-20	2013-11-20	4	ORBIMED ADVISORS LLC See footnotes	RLYP	Series C-2 Preferred Stock	C - Conversion	I			-693,991		0
2013-11-20	2013-11-20	4	ORBIMED ADVISORS LLC See footnotes	RLYP	Series C-1 Preferred Stock	C - Conversion	I			-3,007,297		0
2013-11-20	2013-11-20	4	ORBIMED ADVISORS LLC See footnotes	RLYP	Series B-2 Preferred Stock	C - Conversion	I			-1,905,702		0
2013-11-20	2013-11-20	4	ORBIMED ADVISORS LLC See footnotes	RLYP	Series B-1 Preferred Stock	C - Conversion	I			-1,295,845		0
2013-11-20	2013-11-20	4	ORBIMED ADVISORS LLC See footnotes	RLYP	Common Stock	P - Purchase	I		11.0000	712,192	7,834		9,941,551
2013-11-20	2013-11-20	4	ORBIMED ADVISORS LLC See footnotes	RLYP	Common Stock	F - Taxes	I		11.0000	-5,116	-56		9,229,359
2013-11-20	2013-11-20	4	ORBIMED ADVISORS LLC See footnotes	RLYP	Common Stock	M - Exercise	I		0.1700	327,133	56		9,234,475
2013-11-20	2013-11-20	4	ORBIMED ADVISORS LLC See footnotes	RLYP	Common Stock	F - Taxes	I		11.0000	-22,166	-244		8,907,342
2013-11-20	2013-11-20	4	ORBIMED ADVISORS LLC See footnotes	RLYP	Common Stock	M - Exercise	I		0.1700	1,417,578	241		8,929,508
2013-11-20	2013-11-20	4	ORBIMED ADVISORS LLC See footnotes	RLYP	Common Stock	C - Conversion	I			693,991			7,511,930
2013-11-20	2013-11-20	4	ORBIMED ADVISORS LLC See footnotes	RLYP	Common Stock	C - Conversion	I			3,007,297			6,817,939
2013-11-20	2013-11-20	4	ORBIMED ADVISORS LLC See footnotes	RLYP	Common Stock	C - Conversion	I			1,905,702			3,810,642
2013-11-20	2013-11-20	4	ORBIMED ADVISORS LLC See footnotes	RLYP	Common Stock	C - Conversion	I			1,904,940			1,904,940
2013-11-20	2013-11-20	4	New Leaf Ventures I, L.P.	RLYP	Warrant to Purchase Common Stock	M - Exercise	I	9.18		-25,977		0
2013-11-20	2013-11-20	4	New Leaf Ventures I, L.P.	RLYP	Warrant to Purchase Common Stock	J - Other	I	9.18		25,977		25,977
2013-11-20	2013-11-20	4	New Leaf Ventures I, L.P.	RLYP	Warrant to Purchase Preferred Stock	J - Other	I	13.50		-17,671		0
2013-11-20	2013-11-20	4	New Leaf Ventures I, L.P.	RLYP	Series C-2 Preferred Stock	C - Conversion	I			-125,067		0
2013-11-20	2013-11-20	4	New Leaf Ventures I, L.P.	RLYP	Series C-1 Preferred Stock	C - Conversion	I			-541,960		0
2013-11-20	2013-11-20	4	New Leaf Ventures I, L.P.	RLYP	Series B-2 Preferred Stock	C - Conversion	I			-378,773		0
2013-11-20	2013-11-20	4	New Leaf Ventures I, L.P.	RLYP	Series B-1 Preferred Stock	C - Conversion	I			-259,676		0
2013-11-20	2013-11-20	4	New Leaf Ventures I, L.P.	RLYP	Series A-1 Preferred Stock	C - Conversion	I			-497,093		0
2013-11-20	2013-11-20	4	New Leaf Ventures I, L.P.	RLYP	Common Stock	P - Purchase	I		11.0000	185,978	2,046		2,114,890
2013-11-20	2013-11-20	4	New Leaf Ventures I, L.P.	RLYP	Common Stock	F - Taxes	I		11.0000	-21,691	-239		1,928,912
2013-11-20	2013-11-20	4	New Leaf Ventures I, L.P.	RLYP	Common Stock	M - Exercise	I		9.1848	25,977	239		1,950,603
2013-11-20	2013-11-20	4	New Leaf Ventures I, L.P.	RLYP	Common Stock	C - Conversion	I			125,067			1,924,626
2013-11-20	2013-11-20	4	New Leaf Ventures I, L.P.	RLYP	Common Stock	C - Conversion	I			541,960			1,799,559
2013-11-20	2013-11-20	4	New Leaf Ventures I, L.P.	RLYP	Common Stock	C - Conversion	I			378,773			1,257,599
2013-11-20	2013-11-20	4	New Leaf Ventures I, L.P.	RLYP	Common Stock	C - Conversion	I			381,733			878,826
2013-11-20	2013-11-20	4	New Leaf Ventures I, L.P.	RLYP	Common Stock	C - Conversion	I			497,093			497,093
2013-11-20	2013-11-20	4	5AM Partners II, LLC See Footnotes	RLYP	Warrant to Purchase Common Stock	M - Exercise	I	0.17		-676		0
2013-11-20	2013-11-20	4	5AM Partners II, LLC See Footnotes	RLYP	Warrant to Purchase Common Stock	J - Other	I	0.17		676		676
2013-11-20	2013-11-20	4	5AM Partners II, LLC See Footnotes	RLYP	Warrant to Purchase Preferred Stock	J - Other	I	0.17		-676		0
2013-11-20	2013-11-20	4	5AM Partners II, LLC See Footnotes	RLYP	Warrant to Purchase Common Stock	M - Exercise	I	0.17		-2,931		0
2013-11-20	2013-11-20	4	5AM Partners II, LLC See Footnotes	RLYP	Warrant to Purchase Common Stock	J - Other	I	0.17		2,931		2,931
2013-11-20	2013-11-20	4	5AM Partners II, LLC See Footnotes	RLYP	Warrant to Purchase Preferred Stock	J - Other	I	0.17		-2,931		0
2013-11-20	2013-11-20	4	5AM Partners II, LLC See Footnotes	RLYP	Warrant to Purchase Common Stock	M - Exercise	I	9.18		-1,461		0
2013-11-20	2013-11-20	4	5AM Partners II, LLC See Footnotes	RLYP	Warrant to Purchase Common Stock	J - Other	I	9.18		1,461		1,461
2013-11-20	2013-11-20	4	5AM Partners II, LLC See Footnotes	RLYP	Warrant to Purchase Preferred Stock	J - Other	I	13.50		-994		0
2013-11-20	2013-11-20	4	5AM Partners II, LLC See Footnotes	RLYP	Warrant to Purchase Common Stock	M - Exercise	I	0.17		-17,141		0
2013-11-20	2013-11-20	4	5AM Partners II, LLC See Footnotes	RLYP	Warrant to Purchase Common Stock	J - Other	I	0.17		17,141		17,141
2013-11-20	2013-11-20	4	5AM Partners II, LLC See Footnotes	RLYP	Warrant to Purchase Preferred Stock	J - Other	I	0.17		-17,141		0
2013-11-20	2013-11-20	4	5AM Partners II, LLC See Footnotes	RLYP	Warrant to Purchase Common Stock	M - Exercise	I	0.17		-74,281		0
2013-11-20	2013-11-20	4	5AM Partners II, LLC See Footnotes	RLYP	Warrant to Purchase Common Stock	J - Other	I	0.17		74,281		74,281
2013-11-20	2013-11-20	4	5AM Partners II, LLC See Footnotes	RLYP	Warrant to Purchase Preferred Stock	J - Other	I	0.17		-74,281		0
2013-11-20	2013-11-20	4	5AM Partners II, LLC See Footnotes	RLYP	Warrant to Purchase Common Stock	M - Exercise	I	9.18		-37,056		0
2013-11-20	2013-11-20	4	5AM Partners II, LLC See Footnotes	RLYP	Warrant to Purchase Common Stock	J - Other	I	9.18		37,056		37,056
2013-11-20	2013-11-20	4	5AM Partners II, LLC See Footnotes	RLYP	Warrant to Purchase Preferred Stock	J - Other	I	13.50		-25,208		0
2013-11-20	2013-11-20	4	5AM Partners II, LLC See Footnotes	RLYP	Series C-2 Preferred Stock	C - Conversion	I			-1,888		0
2013-11-20	2013-11-20	4	5AM Partners II, LLC See Footnotes	RLYP	Series C-1 Preferred Stock	C - Conversion	I			-8,181		0
2013-11-20	2013-11-20	4	5AM Partners II, LLC See Footnotes	RLYP	Series B-2 Preferred Stock	C - Conversion	I			-22,765		0
2013-11-20	2013-11-20	4	5AM Partners II, LLC See Footnotes	RLYP	Series B-1 Preferred Stock	C - Conversion	I			-15,260		0
2013-11-20	2013-11-20	4	5AM Partners II, LLC See Footnotes	RLYP	Series A-1 Preferred Stock	C - Conversion	I			-29,876		0
2013-11-20	2013-11-20	4	5AM Partners II, LLC See Footnotes	RLYP	Series C-2 Preferred Stock	C - Conversion	I			-47,849		0
2013-11-20	2013-11-20	4	5AM Partners II, LLC See Footnotes	RLYP	Series C-1 Preferred Stock	C - Conversion	I			-207,347		0
2013-11-20	2013-11-20	4	5AM Partners II, LLC See Footnotes	RLYP	Series B-2 Preferred Stock	C - Conversion	I			-576,958		0
2013-11-20	2013-11-20	4	5AM Partners II, LLC See Footnotes	RLYP	Series B-1 Preferred Stock	C - Conversion	I			-386,754		0
2013-11-20	2013-11-20	4	5AM Partners II, LLC See Footnotes	RLYP	Series A-1 Preferred Stock	C - Conversion	I			-757,187		0
2013-11-20	2013-11-20	4	5AM Partners II, LLC See Footnotes	RLYP	Common Stock	F - Taxes	I		11.0000	-11	-0		89,771
2013-11-20	2013-11-20	4	5AM Partners II, LLC See Footnotes	RLYP	Common Stock	M - Exercise	I		0.1700	676	0		89,782
2013-11-20	2013-11-20	4	5AM Partners II, LLC See Footnotes	RLYP	Common Stock	F - Taxes	I		11.0000	-46	-1		89,106
2013-11-20	2013-11-20	4	5AM Partners II, LLC See Footnotes	RLYP	Common Stock	M - Exercise	I		0.1700	2,931	0		89,152
2013-11-20	2013-11-20	4	5AM Partners II, LLC See Footnotes	RLYP	Common Stock	F - Taxes	I		11.0000	-1,220	-13		86,221
2013-11-20	2013-11-20	4	5AM Partners II, LLC See Footnotes	RLYP	Common Stock	M - Exercise	I		9.1848	1,461	13		87,441
2013-11-20	2013-11-20	4	5AM Partners II, LLC See Footnotes	RLYP	Common Stock	C - Conversion	I			1,888			85,980
2013-11-20	2013-11-20	4	5AM Partners II, LLC See Footnotes	RLYP	Common Stock	C - Conversion	I			8,181			84,092
2013-11-20	2013-11-20	4	5AM Partners II, LLC See Footnotes	RLYP	Common Stock	C - Conversion	I			22,765			75,911
2013-11-20	2013-11-20	4	5AM Partners II, LLC See Footnotes	RLYP	Common Stock	C - Conversion	I			22,432			53,146
2013-11-20	2013-11-20	4	5AM Partners II, LLC See Footnotes	RLYP	Common Stock	C - Conversion	I			29,876			30,714
2013-11-20	2013-11-20	4	5AM Partners II, LLC See Footnotes	RLYP	Common Stock	F - Taxes	I		11.0000	-269	-3		2,275,248
2013-11-20	2013-11-20	4	5AM Partners II, LLC See Footnotes	RLYP	Common Stock	M - Exercise	I		0.1700	17,141	3		2,275,517
2013-11-20	2013-11-20	4	5AM Partners II, LLC See Footnotes	RLYP	Common Stock	F - Taxes	I		11.0000	-1,162	-13		2,258,376
2013-11-20	2013-11-20	4	5AM Partners II, LLC See Footnotes	RLYP	Common Stock	M - Exercise	I		0.1700	74,281	13		2,259,538
2013-11-20	2013-11-20	4	5AM Partners II, LLC See Footnotes	RLYP	Common Stock	F - Taxes	I		11.0000	-30,942	-340		2,185,257
2013-11-20	2013-11-20	4	5AM Partners II, LLC See Footnotes	RLYP	Common Stock	M - Exercise	I		9.1848	37,056	340		2,216,199
2013-11-20	2013-11-20	4	5AM Partners II, LLC See Footnotes	RLYP	Common Stock	C - Conversion	I			47,849			2,179,143
2013-11-20	2013-11-20	4	5AM Partners II, LLC See Footnotes	RLYP	Common Stock	C - Conversion	I			207,347			2,131,294
2013-11-20	2013-11-20	4	5AM Partners II, LLC See Footnotes	RLYP	Common Stock	C - Conversion	I			576,958			1,923,947
2013-11-20	2013-11-20	4	5AM Partners II, LLC See Footnotes	RLYP	Common Stock	C - Conversion	I			568,542			1,346,989
2013-11-20	2013-11-20	4	5AM Partners II, LLC See Footnotes	RLYP	Common Stock	C - Conversion	I			757,187			778,447
2013-11-20	2013-11-20	4	5AM Partners III, LLC See Footnotes	RLYP	Warrant to Purchase Common Stock	M - Exercise	I	0.17		-2,629		0
2013-11-20	2013-11-20	4	5AM Partners III, LLC See Footnotes	RLYP	Warrant to Purchase Common Stock	J - Other	I	0.17		2,629		2,629
2013-11-20	2013-11-20	4	5AM Partners III, LLC See Footnotes	RLYP	Warrant to Purchase Preferred Stock	J - Other	I	0.17		-2,629		0
2013-11-20	2013-11-20	4	5AM Partners III, LLC See Footnotes	RLYP	Warrant to Purchase Common Stock	M - Exercise	I	0.17		-11,395		0
2013-11-20	2013-11-20	4	5AM Partners III, LLC See Footnotes	RLYP	Warrant to Purchase Common Stock	J - Other	I	0.17		11,395		11,395
2013-11-20	2013-11-20	4	5AM Partners III, LLC See Footnotes	RLYP	Warrant to Purchase Preferred Stock	J - Other	I	0.17		-11,395		0
2013-11-20	2013-11-20	4	5AM Partners III, LLC See Footnotes	RLYP	Warrant to Purchase Common Stock	M - Exercise	I	0.17		-102,036		0
2013-11-20	2013-11-20	4	5AM Partners III, LLC See Footnotes	RLYP	Warrant to Purchase Common Stock	J - Other	I	0.17		102,036		102,036
2013-11-20	2013-11-20	4	5AM Partners III, LLC See Footnotes	RLYP	Warrant to Purchase Preferred Stock	J - Other	I	0.17		-102,036		0
2013-11-20	2013-11-20	4	5AM Partners III, LLC See Footnotes	RLYP	Warrant to Purchase Common Stock	M - Exercise	I	0.17		-442,160		0
2013-11-20	2013-11-20	4	5AM Partners III, LLC See Footnotes	RLYP	Warrant to Purchase Common Stock	J - Other	I	0.17		442,160		442,160
2013-11-20	2013-11-20	4	5AM Partners III, LLC See Footnotes	RLYP	Warrant to Purchase Preferred Stock	J - Other	I	0.17		-442,160		0
2013-11-20	2013-11-20	4	5AM Partners III, LLC See Footnotes	RLYP	Series C-2 Preferred Stock	C - Conversion	I			-7,340		0
2013-11-20	2013-11-20	4	5AM Partners III, LLC See Footnotes	RLYP	Series C-1 Preferred Stock	C - Conversion	I			-31,809		0
2013-11-20	2013-11-20	4	5AM Partners III, LLC See Footnotes	RLYP	Series C-2 Preferred Stock	C - Conversion	I			-284,822		0
2013-11-20	2013-11-20	4	5AM Partners III, LLC See Footnotes	RLYP	Series C-1 Preferred Stock	C - Conversion	I			-1,234,230		0
2013-11-20	2013-11-20	4	5AM Partners III, LLC See Footnotes	RLYP	Common Stock	P - Purchase	I		11.0000	9,364	103		62,316
2013-11-20	2013-11-20	4	5AM Partners III, LLC See Footnotes	RLYP	Common Stock	F - Taxes	I		11.0000	-42	-0		52,952
2013-11-20	2013-11-20	4	5AM Partners III, LLC See Footnotes	RLYP	Common Stock	M - Exercise	I		0.1700	2,629	0		52,994
2013-11-20	2013-11-20	4	5AM Partners III, LLC See Footnotes	RLYP	Common Stock	F - Taxes	I		11.0000	-179	-2		50,365
2013-11-20	2013-11-20	4	5AM Partners III, LLC See Footnotes	RLYP	Common Stock	M - Exercise	I		0.1700	11,395	2		50,544
2013-11-20	2013-11-20	4	5AM Partners III, LLC See Footnotes	RLYP	Common Stock	C - Conversion	I			7,340			39,149
2013-11-20	2013-11-20	4	5AM Partners III, LLC See Footnotes	RLYP	Common Stock	C - Conversion	I			31,809			31,809
2013-11-20	2013-11-20	4	5AM Partners III, LLC See Footnotes	RLYP	Common Stock	P - Purchase	I		11.0000	363,328	3,997		2,418,066
2013-11-20	2013-11-20	4	5AM Partners III, LLC See Footnotes	RLYP	Common Stock	F - Taxes	I		11.0000	-1,596	-18		2,054,738
2013-11-20	2013-11-20	4	5AM Partners III, LLC See Footnotes	RLYP	Common Stock	M - Exercise	I		0.1700	102,036	17		2,056,334
2013-11-20	2013-11-20	4	5AM Partners III, LLC See Footnotes	RLYP	Common Stock	F - Taxes	I		11.0000	-6,914	-76		1,954,298
2013-11-20	2013-11-20	4	5AM Partners III, LLC See Footnotes	RLYP	Common Stock	M - Exercise	I		0.1700	442,160	75		1,961,212
2013-11-20	2013-11-20	4	5AM Partners III, LLC See Footnotes	RLYP	Common Stock	C - Conversion	I			284,822			1,519,052
2013-11-20	2013-11-20	4	5AM Partners III, LLC See Footnotes	RLYP	Common Stock	C - Conversion	I			1,234,230			1,234,230
2013-11-18	2013-11-14	4	Butler John P.	RLYP	Stock Option (right to buy)	A - Award	D	11.00		8,247		8,247
2013-11-18	2013-11-14	4	Butler John P.	RLYP	Stock Option (right to buy)	A - Award	D	11.00		16,385		16,385
2013-11-14		3	ROCKLAGE SCOTT M See Footnotes	RLYP	Common Stock		I						21,260
2013-11-14		3	ROCKLAGE SCOTT M See Footnotes	RLYP	Common Stock		I						838
2013-11-14		3	5AM CO-INVESTORS II LP See Footnotes	RLYP	Common Stock		I						21,260
2013-11-14		3	5AM CO-INVESTORS II LP See Footnotes	RLYP	Common Stock		I						838
2013-11-14		3	Buysse Jerry M.	RLYP	Common Stock		D						36,046
2013-11-14		3	Krasnow Ronald A.	RLYP	Common Stock		D						20,348

Pembelian sekuritas non-derivatif atau derivatif di pasar terbuka atau secara pribadi.

Penjualan terbuka atau penjualan pribadi atas sekuritas non-derivatif atau derivatif.

Hibah, penghargaan, atau perolehan sekuritas lainnya dari perusahaan (seperti opsi)

Konversi turunan

Penjualan atau pengalihan sekuritas kembali ke perusahaan.

Pembayaran harga pelaksanaan atau kewajiban pajak menggunakan sebagian sekuritas yang diterima dari perusahaan.

Pemberian sekuritas oleh atau kepada orang dalam.

Swap ekuitas dan transaksi lindung nilai serupa

Pelaksanaan atau konversi sekuritas derivatif yang diterima dari perusahaan (seperti opsi)

Transaksi yang dilaporkan secara sukarela pada Formulir 4.

Lainnya (disertai dengan catatan kaki yang menjelaskan transaksi tersebut)

RLYP / Relypsa, Inc. - Insider Trading and Ownership Report - SEC Form 3, 4, 5