| Jumlah Saham Beredar | 26,832,457 shares |
| Saham Orang Dalam | 1,118,641 shares |
| Kepemilikan oleh Orang Dalam | 4.17 % |
| Orang Dalam Sejati | 61 |
Skor Sentimen Orang Dalam
Skor Sentimen Orang Dalam mengidentifikasi perusahaan yang dibeli oleh orang dalam korporat.
Ini adalah hasil dari model kuantitatif multifaktor yang canggih yang mengidentifikasi perusahaan dengan tingkat akumulasi internal tertinggi. Model penilaian ini menggunakan kombinasi dari jumlah bersih orang dalam yang membeli dalam 90 hari sebelumnya, total saham yang dibeli sebagai persentase dari jumlah saham yang beredar, dan total saham yang dimiliki oleh orang dalam. Angka tersebut berkisar dari 0 hingga 100, dengan angka yang lebih tinggi menunjukkan tingkat akumulasi yang lebih tinggi dibandingkan dengan perusahaan sejenis, dan 50 adalah rata-rata.
Frekuensi Pembaruan: Setiap Hari
Skor Sentimen Petugas
Skor Sentimen Pejabat menemukan perusahaan yang dibeli oleh Pejabat Korporat.
Menurut definisi, Pejabat Korporasi adalah Orang Dalam Korporasi, tetapi tidak seperti beberapa Orang Dalam lainnya (Pemegang Saham 10% dan Anggota Dewan), Pejabat bekerja untuk perusahaan setiap hari, dan mereka menggunakan uang mereka sendiri saat bertransaksi . (Pemegang Saham 10% dan Anggota Dewan seringkali adalah manajer dana yang mengelola uang orang lain.) Dengan demikian, transaksi orang dalam yang dilakukan oleh Pejabat jauh lebih signifikan dan harus ditangani dengan tepat.
Seperti Skor Sentimen Internal, Skor Sentimen Pejabat adalah hasil dari model kuantitatif multi-faktor yang canggih yang mengidentifikasi perusahaan dengan tingkat akumulasi pejabat tertinggi.
Frekuensi Pembaruan: Setiap Hari
Metrik Utama Orang Dalam
Kartu ini menunjukkan peringkat perusahaan berdasarkan berbagai metrik internal. Peringkat persentil menunjukkan bagaimana perusahaan ini dibandingkan dengan perusahaan lain di pasar AS. Peringkat yang lebih tinggi menunjukkan situasi yang lebih baik.
Sebagai contoh, secara umum diterima bahwa pembelian oleh orang dalam perusahaan adalah indikator positif, sehingga perusahaan dengan lebih banyak pembelian oleh orang dalam akan mendapat peringkat lebih tinggi daripada perusahaan dengan lebih sedikit pembelian oleh orang dalam (atau bahkan penjualan oleh orang dalam).
Jumlah Bersih Pembelian oleh Orang Dalam (Peringkat)
0 ( )
1264 out of 11323Jumlah Bersih Pembelian oleh Orang Dalam adalah total jumlah orang dalam yang membeli dikurangi total jumlah orang dalam yang menjual dalam 90 hari terakhir. Peringkat persentil ditunjukkan di sini (kisaran dari 0 hingga 100%).
Persentase Saham yang Dibeli oleh Orang Dalam (Peringkat)
0.000 %( )
1259 out of 11244Persentase Saham yang Dibeli oleh Orang Dalam adalah total jumlah saham yang dibeli oleh orang dalam dikurangi total jumlah saham yang dijual oleh orang dalam dalam 90 hari terakhir, dibagi dengan total jumlah saham yang beredar dan dikalikan dengan 100.
Grafik Perdagangan Orang Dalam
Grafik berikut menunjukkan Syros Pharmaceuticals, Inc. transaksi orang dalam. Orang dalam adalah pejabat, direktur, atau investor signifikan dalam suatu perusahaan. Secara umum, melakukan transaksi di perusahaan mereka berdasarkan informasi material yang belum dipublikasikan adalah ilegal bagi orang dalam. Ini tidak berarti bahwa mereka dilarang melakukan transaksi apa pun di perusahaan mereka sendiri. Namun, mereka wajib melaporkan semua transaksi kepada SEC melalui Formulir 4.
Daftar Orang Dalam dan Metrik Profitabilitas
Tabel ini menampilkan daftar orang dalam yang diketahui, dan dibuat secara otomatis dari pengajuan yang diungkapkan kepada SEC. Selain nama, jabatan terbaru, dan sebutan direktur, pejabat, atau pemilik 10%, kami memberikan kepemilikan terbaru yang diungkapkan. Selain itu, jika memungkinkan, kami memberikan kinerja perdagangan historis untuk orang dalam tersebut. Kinerja perdagangan historis adalah rata-rata tertimbang dari kinerja transaksi pembelian pasar terbuka aktual yang dilakukan oleh orang dalam tersebut. Untuk informasi lebih lanjut tentang bagaimana ini dihitung, tonton webinar YouTube ini.
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| Orang Dalam | Rata-rata Keuntungan (%) | Saham Dimiliki |
Terbagi Disesuaikan |
|---|---|---|---|
|
Noubar Afeyan
10% Owner -
|
0 | 0 | |
|
Aisling Capital Iii Lp
10% Owner -
|
908,565 | 90,856 | |
| Srinivas Akkaraju Director - [D] | 9,333 | 9,333 | |
|
ARCH Venture Partners VII, L.P.
10% Owner -
|
4,242,051 | 424,205 | |
|
ARCH Venture Partners VII, LLC
10% Owner -
|
4,242,051 | 424,205 | |
|
Aisling Capital Partners III LLC
10% Owner -
|
908,565 | 90,856 | |
|
Aisling Capital Partners III LP
10% Owner -
|
908,565 | 90,856 | |
| Mark J Alles Director - [D] | 3,666 | 3,666 | |
|
Arch Venture Fund VII LP
10% Owner -
|
4,242,051 | 424,205 | |
| Michael W Bonney | 11,000 | ||
|
Clinton Bybee
10% Owner -
|
4,242,051 | 424,205 | |
| Stephane Bancel Director - [D] | 47,980 | 4,798 | |
|
Keith Crandell
10% Owner -
|
4,242,051 | 424,205 | |
| Conley Chee President & CEO, Director - [D] [O] | 0 | 0 | |
|
Management Co Deerfield
10% Owner -
|
628,566 | 62,857 | |
| Colleen Elizabeth DeSimone Principal Accounting Officer - [O] | 0 | 0 | |
|
Deerfield Mgmt III, L.P.
10% Owner -
|
628,566 | 62,857 | |
|
Deerfield Mgmt L.P.
10% Owner -
|
628,566 | 62,857 | |
|
Deerfield Private Design Fund III, L.P.
10% Owner -
|
628,566 | 62,857 | |
|
Deerfield Special Situations Fund, L.P.
10% Owner -
|
628,566 | 62,857 |
| Orang Dalam | Rata-rata Keuntungan (%) | Saham Dimiliki |
Terbagi Disesuaikan |
|---|---|---|---|
| Deborah Dunsire Director - [D] | 12,000 | 12,000 | |
|
Steve Elms
10% Owner -
|
908,565 | 90,856 | |
| Sue Gail Eckhardt Director - [D] | 16,000 | 16,000 | |
| Marsha Fanucci Director - [D] | 16,000 | 16,000 | |
| Joseph J Jr Ferra Chief Financial Officer - [O] | 87,000 | 8,700 | |
|
Flagship VentureLabs IV, LLC
10% Owner -
|
0 | 0 | |
|
Flagship Ventures Fund IV General Partner LLC
10% Owner -
|
0 | 0 | |
|
Flagship Ventures Fund IV, L.P.
10% Owner -
|
0 | 0 | |
|
Flagship Ventures Fund IV-Rx, L.P.
10% Owner -
|
0 | 0 | |
|
James E Flynn
10% Owner -
|
628,566 | 62,857 | |
|
Nathanael Gray
10% Owner -
|
853,332 | 85,333 | |
|
Jeremy Green
10% Owner -
|
49,793 | 4,979 | |
| Jason Haas Chief Financial Officer - [O] | 0 | 0 | |
|
JEB Syros Trust
10% Owner -
|
703,332 | 70,333 | |
|
Edwin M Jr Kania
10% Owner -
|
0 | 0 | |
| Kuvalanka Kyle D. | 78,000 | ||
|
Robert Nelsen
10% Owner -
|
4,242,051 | 424,205 | |
|
Amir Nashat
Director, 10% Owner -
[D]
|
48,320 | 4,832 | |
| Oh Andrew M. Director - [D] | 16,000 | 16,000 | |
| Eric R Olson Chief Scientific Officer - [O] | 6,661 | 6,661 |
| Orang Dalam | Rata-rata Keuntungan (%) | Saham Dimiliki |
Terbagi Disesuaikan |
|---|---|---|---|
| Sanj K Patel | 11,000 | ||
|
Perspecta Trust LLC
10% Owner -
|
703,332 | 70,333 | |
|
Polaris Entrepreneurs' Fund VII, L.P.
10% Owner -
|
48,320 | 4,832 | |
|
Polaris Management Co. VII, L.L.C.
10% Owner -
|
48,320 | 4,832 | |
|
Polaris Partners VII, L.P.
10% Owner -
|
48,320 | 4,832 | |
|
Dennis J Purcell
10% Owner -
|
908,565 | 90,856 | |
| Gerald E Quirk Chief Legal & Compliance Offic - [O] | 0 | 0 | |
|
Redmile Group, LLC
10% Owner -
|
49,793 | 4,979 | |
| David Roth Chief Medical Officer - [O] | 0 | 0 | |
| Vicki L Sato | 11,000 | ||
|
Andrew N Schiff
10% Owner -
|
908,565 | 90,856 | |
| Philip A Sharp Director - [D] | 40,000 | 4,000 | |
| Alice Tsang Shaw | 22,000 | ||
| Nancy A Simonian Director - [D] | 4,000 | 4,000 | |
| Springhorn Jeremy P. Chief Business Officer - [O] | 35,000 | 3,500 | |
| Kristin Stephens Chief Development Officer - [O] | 0 | 0 | |
| Timothy Tyson Director - [D] | 33,189 | 33,189 | |
| Peter Wirth Director - [D] | 16,000 | 16,000 | |
|
WuXi Healthcare Ventures II, L.P.
10% Owner -
|
423,805 | 42,380 | |
|
WuXi PharmTech Healthcare Fund I L.P.
10% Owner -
|
931,857 | 93,186 | |
| Richard A Young Director - [D] | 10,667 | 10,667 |
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Rekam Jejak Pembelian Orang Dalam - Analisis Keuntungan Jangka Pendek
Pada bagian ini, kami menganalisis profitabilitas setiap pembelian saham oleh orang dalam di pasar terbuka yang tidak direncanakan yang dilakukan di SYRS / Syros Pharmaceuticals, Inc.. Analisis ini membantu memahami apakah orang dalam tersebut secara konsisten menghasilkan pengembalian abnormal, dan layak untuk diikuti. Analisis ini dilakukan selama satu tahun setelah setiap transaksi, dan hasilnya bersifat teoretis .
Tabel berikut menunjukkan pembelian pasar terbuka terbaru yang bukan bagian dari rencana perdagangan otomatis.
Harga yang Disesuaikan adalah harga yang disesuaikan dengan pemisahan saham. Ang Adjusted Shares ay ang jumlah saham yang disesuaikan dengan pemisahan saham (stock split).
Rekam Jejak Penjualan Orang Dalam - Analisis Kerugian Jangka Pendek
Dalam bagian ini, kami menganalisis penghindaran kerugian jangka pendek dari setiap penjualan dalam pasar terbuka yang tidak direncanakan oleh orang dalam yang dilakukan di SYRS / Syros Pharmaceuticals, Inc.. Pola penghindaran kerugian yang konsisten dapat menunjukkan bahwa transaksi penjualan di masa mendatang dapat memprediksi penurunan harga. Analisis ini berlaku untuk satu tahun setelah setiap perdagangan, dan hasilnya bersifat teoretis .
Tabel berikut menunjukkan penjualan pasar terbuka terbaru yang bukan bagian dari rencana perdagangan otomatis.
Harga yang Disesuaikan adalah harga yang disesuaikan dengan pemisahan saham. Ang Adjusted Shares ay ang jumlah saham yang disesuaikan dengan pemisahan saham (stock split).
Riwayat Transaksi
Klik ikon tautan untuk melihat riwayat transaksi lengkap. Transaksi yang dilaporkan sebagai bagian dari rencana perdagangan otomatis 10b5-1 akan memiliki tanda X di kolom yang bertanda 10b-5.
| Berkas Tanggal |
Perdagangan Tanggal |
Formulir | Orang Dalam | Ticker | Judul Keamanan | Kode | Langsung | Latihan Harga |
Satuan Harga |
Unit Diubah |
Nilai Diubah (1 ribu) |
Sisa Pilihan |
Sisa Saham |
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2024-12-04 | 2024-12-02 | 4 | Simonian Nancy A | SYRS | Common Stock | D | 0.2702 | -37,070 | -10 | 4,000 | ||||
| 2024-11-27 | 2024-11-25 | 4 | Simonian Nancy A | SYRS | Common Stock | D | 0.2653 | -134,713 | -36 | 41,070 | ||||
| 2024-11-20 | 2024-11-18 | 4 | Haas Jason | SYRS | Common Stock | D | 0.2103 | -137,803 | -29 | 0 | ||||
| 2024-11-20 | 2024-11-18 | 4 | Chee Conley | SYRS | Common Stock | D | 0.1998 | -134,797 | -27 | 0 | ||||
| 2024-11-20 | 2024-11-19 | 4 | Quirk Gerald E | SYRS | Common Stock | D | 0.2212 | -46,657 | -10 | 0 | ||||
| 2024-11-20 | 2024-11-18 | 4 | Stephens Kristin | SYRS | Common Stock | D | 0.2200 | -36,133 | -8 | 0 | ||||
| 2024-11-20 | 2024-11-18 | 4 | Roth David | SYRS | Common Stock | D | 0.1969 | -12,099 | -2 | 0 | ||||
| 2024-11-04 | 2024-10-31 | 4 | Simonian Nancy A | SYRS | Common Stock | D | 40,125 | 175,783 | ||||||
| 2024-11-04 | 2024-10-31 | 4 | Chee Conley | SYRS | Common Stock | D | 2.0900 | -8,707 | -18 | 130,797 | ||||
| 2024-11-04 | 2024-10-31 | 4 | Chee Conley | SYRS | Common Stock | D | 17,000 | 139,504 | ||||||
| 2024-11-04 | 2024-10-31 | 4 | Roth David | SYRS | Common Stock | D | 2.0900 | -6,776 | -14 | 12,099 | ||||
| 2024-11-04 | 2024-10-31 | 4 | Roth David | SYRS | Common Stock | D | 18,875 | 18,875 | ||||||
| 2024-11-04 | 2024-10-31 | 4 | Haas Jason | SYRS | Common Stock | D | 2.0900 | -5,624 | -12 | 137,803 | ||||
| 2024-11-04 | 2024-10-31 | 4 | Haas Jason | SYRS | Common Stock | D | 18,875 | 143,427 | ||||||
| 2024-11-04 | 2024-10-31 | 4 | Stephens Kristin | SYRS | Common Stock | D | 2.0900 | -6,104 | -13 | 36,133 | ||||
| 2024-11-04 | 2024-10-31 | 4 | Stephens Kristin | SYRS | Common Stock | D | 17,000 | 42,237 | ||||||
| 2024-10-02 | 2024-09-30 | 4 | Quirk Gerald E | SYRS | Common Stock | D | 2.1000 | -3,100 | -7 | 46,657 | ||||
| 2024-10-02 | 2024-09-30 | 4 | Quirk Gerald E | SYRS | Common Stock | D | 10,000 | 49,757 | ||||||
| 2024-09-18 | 2024-09-16 | 4 | Young Richard A | SYRS | Common Stock | D | 2,667 | 10,667 | ||||||
| 2024-09-18 | 2024-09-16 | 4 | AKKARAJU SRINIVAS | SYRS | Common Stock | D | 2,667 | 9,333 | ||||||
| 2024-09-12 | 2024-09-11 | 4 | Chee Conley | SYRS | Common Stock | D | 1.7084 | 50,000 | 85 | 122,504 | ||||
| 2024-09-12 | 2024-09-10 | 4 | Chee Conley | SYRS | Common Stock | D | 1.5052 | 50,000 | 75 | 72,504 | ||||
| 2024-09-12 | 2024-09-12 | 4 | Haas Jason | SYRS | Common Stock | D | 1.6762 | 45,344 | 76 | 124,552 | ||||
| 2024-09-12 | 2024-09-11 | 4 | Haas Jason | SYRS | Common Stock | D | 1.5781 | 19,293 | 30 | 79,208 | ||||
| 2024-09-12 | 2024-09-10 | 4 | Haas Jason | SYRS | Common Stock | D | 1.5493 | 35,363 | 55 | 59,915 | ||||
| 2024-07-02 | 2024-06-28 | 4 | Young Richard A | SYRS | Common Stock | D | 5.1200 | -34,837 | -178 | 8,000 | ||||
| 2024-06-07 | 2024-06-05 | 4 | OH ANDREW M. | SYRS | Common Stock | D | 4,000 | 16,000 | ||||||
| 2024-06-07 | 2024-06-05 | 4 | Simonian Nancy A | SYRS | Common Stock | D | 4,000 | 135,658 | ||||||
| 2024-06-07 | 2024-06-05 | 4 | WIRTH PETER | SYRS | Common Stock | D | 4,000 | 16,000 | ||||||
| 2024-06-07 | 2024-06-05 | 4 | Fanucci Marsha | SYRS | Common Stock | D | 4,000 | 16,000 | ||||||
| 2024-06-07 | 2024-06-05 | 4 | Eckhardt Sue Gail | SYRS | Common Stock | D | 4,000 | 16,000 | ||||||
| 2024-06-07 | 2024-06-05 | 4 | TYSON TIMOTHY | SYRS | Common Stock | D | 4,000 | 33,189 | ||||||
| 2024-06-07 | 2024-06-05 | 4 | Young Richard A | SYRS | Common Stock | D | 4,000 | 42,837 | ||||||
| 2024-06-04 | 2024-06-01 | 4 | Dunsire Deborah | SYRS | Common Stock | D | 4,000 | 12,000 | ||||||
| 2024-06-04 | 2024-06-01 | 4 | AKKARAJU SRINIVAS | SYRS | Common Stock | D | 4,000 | 6,666 | ||||||
| 2024-04-05 | 2024-04-03 | 4 | Roth David | SYRS | Common Stock | D | 4.9500 | -10,451 | -52 | 0 | ||||
| 2024-04-02 | 2024-04-01 | 4 | Stephens Kristin | SYRS | Common Stock | D | 5.1200 | -4,218 | -22 | 25,237 | ||||
| 2024-04-02 | 2024-03-31 | 4 | Stephens Kristin | SYRS | Common Stock | D | 11,666 | 29,455 | ||||||
| 2024-04-02 | 2024-03-31 | 4 | Stephens Kristin | SYRS | Common Stock | D | 2,000 | 17,789 | ||||||
| 2024-04-02 | 2024-04-01 | 4 | Simonian Nancy A | SYRS | Common Stock | D | 5.1200 | -14,052 | -72 | 131,658 | ||||
| 2024-04-02 | 2024-03-31 | 4 | Simonian Nancy A | SYRS | Common Stock | D | 39,566 | 145,710 | ||||||
| 2024-04-02 | 2024-03-31 | 4 | Simonian Nancy A | SYRS | Common Stock | D | 6,000 | 106,144 | ||||||
| 2024-04-02 | 2024-04-02 | 4 | Roth David | SYRS | Common Stock | D | 4.9803 | -150 | -1 | 10,451 | ||||
| 2024-04-02 | 2024-04-01 | 4 | Roth David | SYRS | Common Stock | D | 5.1200 | -4,732 | -24 | 10,601 | ||||
| 2024-04-02 | 2024-03-31 | 4 | Roth David | SYRS | Common Stock | D | 13,333 | 15,333 | ||||||
| 2024-04-02 | 2024-03-31 | 4 | Roth David | SYRS | Common Stock | D | 2,000 | 2,000 | ||||||
| 2024-04-02 | 2024-03-28 | 4 | Quirk Gerald E | SYRS | Common Stock | D | 5.5900 | -7,046 | -39 | 39,757 | ||||
| 2024-04-02 | 2024-03-27 | 4 | Quirk Gerald E | SYRS | Common Stock | D | 22,500 | 46,803 | ||||||
| 2024-04-02 | 2024-04-01 | 4 | Haas Jason | SYRS | Common Stock | D | 5.1200 | -4,732 | -24 | 24,552 | ||||
| 2024-04-02 | 2024-03-31 | 4 | Haas Jason | SYRS | Common Stock | D | 13,333 | 29,284 | ||||||
| 2024-04-02 | 2024-03-31 | 4 | Haas Jason | SYRS | Common Stock | D | 2,000 | 15,951 | ||||||
| 2024-04-02 | 2024-04-01 | 4 | Chee Conley | SYRS | Common Stock | D | 5.1200 | -3,500 | -18 | 22,504 | ||||
| 2024-04-02 | 2024-03-31 | 4 | Chee Conley | SYRS | Common Stock | D | 11,666 | 26,004 | ||||||
| 2024-04-02 | 2024-03-31 | 4 | Chee Conley | SYRS | Common Stock | D | 2,000 | 14,338 | ||||||
| 2023-12-26 | 2023-12-21 | 4 | AKKARAJU SRINIVAS By Samsara BioCapital, L.P. | SYRS | Common Stock | I | 4.4200 | 904,977 | 4,000 | 1,786,427 | ||||
| 2023-12-14 | 2023-12-12 | 4 | Roth David | SYRS | Common Stock | D | 4.9500 | -6,287 | -31 | 0 | ||||
| 2023-12-08 | 2023-12-06 | 4 | Roth David | SYRS | Common Stock | D | 3.9500 | -6,287 | -25 | 6,287 | ||||
| 2023-11-02 | 2023-11-01 | 4 | Simonian Nancy A | SYRS | Common Stock | D | 2.2200 | -13,401 | -30 | 100,144 | ||||
| 2023-11-02 | 2023-10-31 | 4 | Simonian Nancy A | SYRS | Common Stock | D | 40,125 | 113,545 | ||||||
| 2023-11-02 | 2023-11-01 | 4 | Haas Jason | SYRS | Common Stock | D | 2.2200 | -6,301 | -14 | 13,951 | ||||
| 2023-11-02 | 2023-10-31 | 4 | Haas Jason | SYRS | Common Stock | D | 18,875 | 20,252 | ||||||
| 2023-11-02 | 2023-11-01 | 4 | Stephens Kristin | SYRS | Common Stock | D | 2.2200 | -5,676 | -13 | 15,789 | ||||
| 2023-11-02 | 2023-10-31 | 4 | Stephens Kristin | SYRS | Common Stock | D | 17,000 | 21,465 | ||||||
| 2023-11-02 | 2023-11-01 | 4 | Roth David | SYRS | Common Stock | D | 2.2200 | -6,301 | -14 | 12,574 | ||||
| 2023-11-02 | 2023-10-31 | 4 | Roth David | SYRS | Common Stock | D | 18,875 | 18,875 | ||||||
| 2023-11-02 | 2023-11-01 | 4 | Chee Conley | SYRS | Common Stock | D | 2.2200 | -6,004 | -13 | 12,338 | ||||
| 2023-11-02 | 2023-10-31 | 4 | Chee Conley | SYRS | Common Stock | D | 17,000 | 18,342 | ||||||
| 2023-10-20 | 2023-10-19 | 4 | Quirk Gerald E | SYRS | Common Stock | D | 2.1000 | -6,897 | -14 | 24,303 | ||||
| 2023-10-20 | 2023-10-11 | 4 | Quirk Gerald E | SYRS | Common Stock | D | 22,500 | 31,200 | ||||||
| 2023-09-19 | 2023-09-16 | 4 | Young Richard A | SYRS | Common Stock | D | 2,666 | 38,837 | ||||||
| 2023-09-19 | 2023-09-16 | 4 | AKKARAJU SRINIVAS | SYRS | Common Stock | D | 2,666 | 2,666 | ||||||
| 2023-09-19 | 2023-09-16 | 4 | Alles Mark J | SYRS | Common Stock | D | 2,666 | 3,666 | ||||||
| 2023-08-02 | 2023-07-31 | 4 | Roth David | SYRS | Common Stock | D | 3.9500 | -7,348 | -29 | 0 | ||||
| 2023-07-18 | 2023-07-17 | 4 | Olson Eric R | SYRS | Common Stock | D | 3.5000 | -689 | -2 | 6,661 | ||||
| 2023-06-02 | 2023-06-01 | 4 | WIRTH PETER | SYRS | Common Stock | D | 4,000 | 12,000 | ||||||
| 2023-06-02 | 2023-06-01 | 4 | Young Richard A | SYRS | Common Stock | D | 4,000 | 36,171 | ||||||
| 2023-06-02 | 2023-06-01 | 4 | OH ANDREW M. | SYRS | Common Stock | D | 4,000 | 12,000 | ||||||
| 2023-06-02 | 2023-06-01 | 4 | TYSON TIMOTHY | SYRS | Common Stock | D | 4,000 | 29,189 | ||||||
| 2023-06-02 | 2023-06-01 | 4 | Eckhardt Sue Gail | SYRS | Common Stock | D | 4,000 | 12,000 | ||||||
| 2023-06-02 | 2023-06-01 | 4 | Fanucci Marsha | SYRS | Common Stock | D | 4,000 | 12,000 | ||||||
| 2023-04-20 | 2022-09-16 | 4/A | TYSON TIMOTHY | SYRS | Common Stock | D | 257 | 8,257 | ||||||
| 2023-04-20 | 2022-09-16 | 4/A | TYSON TIMOTHY | SYRS | Common Stock | D | 8,000 | 8,000 | ||||||
| 2023-04-20 | 2022-09-16 | 4/A | AKKARAJU SRINIVAS | SYRS | Common Stock | I | 691,489 | 881,450 | ||||||
| 2023-04-04 | 2023-04-03 | 4 | Chee Conley | SYRS | Common Stock | D | 2.5800 | -658 | -2 | 1,342 | ||||
| 2023-04-04 | 2023-03-31 | 4 | Chee Conley | SYRS | Common Stock | D | 2,000 | 2,000 | ||||||
| 2023-04-04 | 2023-04-03 | 4 | Olson Eric R | SYRS | Common Stock | D | 2.5800 | -623 | -2 | 7,350 | ||||
| 2023-04-04 | 2023-03-31 | 4 | Olson Eric R | SYRS | Common Stock | D | 2,000 | 7,973 | ||||||
| 2023-04-04 | 2023-04-03 | 4 | Stephens Kristin | SYRS | Common Stock | D | 2.5800 | -623 | -2 | 4,465 | ||||
| 2023-04-04 | 2023-03-31 | 4 | Stephens Kristin | SYRS | Common Stock | D | 2,000 | 5,088 | ||||||
| 2023-04-04 | 2023-04-03 | 4 | Simonian Nancy A | SYRS | Common Stock | D | 2.5800 | -1,852 | -5 | 73,420 | ||||
| 2023-04-04 | 2023-03-31 | 4 | Simonian Nancy A | SYRS | Common Stock | D | 6,000 | 75,272 | ||||||
| 2023-04-04 | 2023-04-03 | 4 | Haas Jason | SYRS | Common Stock | D | 2.5800 | -623 | -2 | 1,377 | ||||
| 2023-04-04 | 2023-03-31 | 4 | Haas Jason | SYRS | Common Stock | D | 2,000 | 2,000 | ||||||
| 2023-04-04 | 2023-04-03 | 4 | Roth David | SYRS | Common Stock | D | 2.5800 | -623 | -2 | 7,348 | ||||
| 2023-04-04 | 2023-03-31 | 4 | Roth David | SYRS | Common Stock | D | 2,000 | 7,971 | ||||||
| 2022-10-13 | 3 | Quirk Gerald E | SYRS | Common Stock | D | 8,700 | ||||||||
| 2022-10-03 | 2022-09-30 | 4 | TYSON TIMOTHY | SYRS | Common Stock | D | 6.3704 | 14,000 | 89 | 24,932 | ||||
| 2022-10-03 | 2022-09-29 | 4 | TYSON TIMOTHY | SYRS | Common Stock | D | 5.7196 | 2,932 | 17 | 10,932 | ||||
| 2022-09-19 | 2022-09-16 | 4 | WIRTH PETER | SYRS | Common Stock | D | 8,000 | 8,000 | ||||||
| 2022-09-19 | 2022-09-16 | 4 | Fanucci Marsha | SYRS | Common Stock | D | 8,000 | 8,000 | ||||||
| 2022-09-19 | 2022-09-16 | 4 | OH ANDREW M. | SYRS | Common Stock | D | 8,000 | 8,000 | ||||||
| 2022-09-19 | 2022-09-16 | 4 | TYSON TIMOTHY | SYRS | Common Stock | D | 8,000 | 8,000 | ||||||
| 2022-09-19 | 2022-09-16 | 4 | Eckhardt Sue Gail | SYRS | Common Stock | D | 8,000 | 8,000 | ||||||
| 2022-09-19 | 2022-09-16 | 4 | Dunsire Deborah | SYRS | Common Stock | D | 8,000 | 8,000 | ||||||
| 2022-04-04 | 2022-04-01 | 4 | Roth David | SYRS | Common Stock | D | 1.1200 | -27,281 | -31 | 59,719 | ||||
| 2022-04-04 | 2022-04-01 | 4 | Stephens Kristin | SYRS | Common Stock | D | 1.1200 | -14,115 | -16 | 30,885 | ||||
| 2022-04-04 | 2022-04-01 | 4 | Simonian Nancy A | SYRS | Common Stock | D | 1.1200 | -58,883 | -66 | 692,723 | ||||
| 2022-04-04 | 2022-04-01 | 4 | Olson Eric R | SYRS | Common Stock | D | 1.1200 | -27,266 | -31 | 59,734 | ||||
| 2022-02-17 | 2022-02-15 | 4 | Simonian Nancy A | SYRS | Restricted Stock Units | D | 400,000 | 400,000 | ||||||
| 2022-02-17 | 2022-02-15 | 4 | Simonian Nancy A | SYRS | Restricted Stock Units | D | 240,000 | 240,000 | ||||||
| 2022-02-17 | 2022-02-15 | 4 | Simonian Nancy A | SYRS | Stock Option (right to buy) | D | 1.59 | 375,000 | 375,000 | |||||
| 2022-02-17 | 2022-02-15 | 4 | Roth David | SYRS | Restricted Stock Units | D | 200,000 | 200,000 | ||||||
| 2022-02-17 | 2022-02-15 | 4 | Roth David | SYRS | Restricted Stock Units | D | 80,000 | 80,000 | ||||||
| 2022-02-17 | 2022-02-15 | 4 | Roth David | SYRS | Stock Option (right to buy) | D | 1.59 | 125,000 | 125,000 | |||||
| 2022-02-17 | 2022-02-15 | 4 | Olson Eric R | SYRS | Restricted Stock Units | D | 200,000 | 200,000 | ||||||
| 2022-02-17 | 2022-02-15 | 4 | Olson Eric R | SYRS | Restricted Stock Units | D | 80,000 | 80,000 | ||||||
| 2022-02-17 | 2022-02-15 | 4 | Olson Eric R | SYRS | Stock Option (right to buy) | D | 1.59 | 100,000 | 100,000 | |||||
| 2022-02-17 | 2022-02-15 | 4 | Stephens Kristin | SYRS | Restricted Stock Units | D | 200,000 | 200,000 | ||||||
| 2022-02-17 | 2022-02-15 | 4 | Stephens Kristin | SYRS | Restricted Stock Units | D | 80,000 | 80,000 | ||||||
| 2022-02-17 | 2022-02-15 | 4 | Stephens Kristin | SYRS | Stock Option (right to buy) | D | 1.59 | 100,000 | 100,000 | |||||
| 2022-02-17 | 2022-02-15 | 4 | Haas Jason | SYRS | Restricted Stock Units | D | 80,000 | 80,000 | ||||||
| 2022-02-17 | 2022-02-15 | 4 | Haas Jason | SYRS | Stock Option (right to buy) | D | 1.59 | 125,000 | 125,000 | |||||
| 2022-02-17 | 2022-02-15 | 4 | Chee Conley | SYRS | Restricted Stock Units | D | 80,000 | 80,000 | ||||||
| 2022-02-17 | 2022-02-15 | 4 | Chee Conley | SYRS | Stock Option (right to buy) | D | 1.59 | 100,000 | 100,000 | |||||
| 2022-01-06 | 2022-01-05 | 4 | Olson Eric R | SYRS | Common Stock | D | 3.4669 | -2,208 | -8 | 0 | ||||
| 2021-10-13 | 2021-10-12 | 4 | Haas Jason | SYRS | Stock Option (right to buy) | D | 4.54 | 750,000 | 750,000 | |||||
| 2021-09-28 | 2021-09-27 | 4 | Chee Conley | SYRS | Stock Option (right to buy) | D | 4.81 | 360,000 | 360,000 | |||||
| 2021-09-10 | 2021-09-09 | 4 | Dunsire Deborah | SYRS | Stock Option (right to buy) | D | 5.28 | 35,000 | 35,000 | |||||
| 2021-07-01 | 2021-07-01 | 4 | Olson Eric R | SYRS | Common Stock | D | 5.5500 | -1,164 | -6 | 0 | ||||
| 2021-06-10 | 2021-06-08 | 4 | AKKARAJU SRINIVAS | SYRS | Stock Option (right to buy) | D | 6.30 | 17,500 | 17,500 | |||||
| 2021-06-10 | 2021-06-08 | 4 | Young Richard A | SYRS | Stock Option (right to buy) | D | 6.30 | 17,500 | 17,500 | |||||
| 2021-06-10 | 2021-06-08 | 4 | WIRTH PETER | SYRS | Stock Option (right to buy) | D | 6.30 | 17,500 | 17,500 | |||||
| 2021-06-10 | 2021-06-08 | 4 | SHARP PHILIP A | SYRS | Stock Option (right to buy) | D | 6.30 | 17,500 | 17,500 | |||||
| 2021-06-10 | 2021-06-08 | 4 | Fanucci Marsha | SYRS | Stock Option (right to buy) | D | 6.30 | 17,500 | 17,500 | |||||
| 2021-06-10 | 2021-06-08 | 4 | Nashat Amir | SYRS | Stock Option (right to buy) | D | 6.30 | 17,500 | 17,500 | |||||
| 2021-06-10 | 2021-06-08 | 4 | Eckhardt Sue Gail | SYRS | Stock Option (right to buy) | D | 6.30 | 17,500 | 17,500 | |||||
| 2021-06-10 | 2021-06-08 | 4 | Alles Mark J | SYRS | Stock Option (right to buy) | D | 6.30 | 17,500 | 17,500 | |||||
| 2021-06-10 | 3 | Stephens Kristin | SYRS | Common Stock | D | 45,000 | ||||||||
| 2021-03-17 | 2021-03-15 | 4 | Olson Eric R | SYRS | Stock Option (right to buy) | D | 1.01 | -3,628 | 90,697 | |||||
| 2021-03-17 | 2021-03-15 | 4 | Olson Eric R | SYRS | Common Stock | D | 9.4740 | -3,628 | -34 | 0 | ||||
| 2021-03-17 | 2021-03-15 | 4 | Olson Eric R | SYRS | Common Stock | D | 1.0100 | 3,628 | 4 | 3,628 | ||||
| 2021-02-19 | 2021-02-17 | 4 | Springhorn Jeremy P. | SYRS | Stock Option (right to buy) | D | 11.41 | 94,000 | 94,000 | |||||
| 2021-02-19 | 2021-02-17 | 4 | Quirk Gerald E | SYRS | Stock Option (right to buy) | D | 11.41 | 94,000 | 94,000 | |||||
| 2021-02-19 | 2021-02-17 | 4 | Olson Eric R | SYRS | Stock Option (right to buy) | D | 11.41 | 94,000 | 94,000 | |||||
| 2021-02-19 | 2021-02-17 | 4 | Roth David | SYRS | Stock Option (right to buy) | D | 11.41 | 119,000 | 119,000 | |||||
| 2021-02-19 | 2021-02-17 | 4 | Ferra Joseph J Jr | SYRS | Stock Option (right to buy) | D | 11.41 | 119,000 | 119,000 | |||||
| 2021-02-19 | 2021-02-17 | 4 | Simonian Nancy A | SYRS | Stock Option (right to buy) | D | 11.41 | 304,000 | 304,000 | |||||
| 2021-02-18 | 2021-02-16 | 4 | Young Richard A | SYRS | Common Stock | D | 12.0500 | -3,750 | -45 | 321,711 | ||||
| 2021-02-10 | 2020-11-17 | 4/A | Young Richard A | SYRS | Common Stock | D | 8.7500 | -5,357 | -47 | 329,211 | ||||
| 2021-02-10 | 2020-11-16 | 4/A | Young Richard A | SYRS | Common Stock | D | 8.9800 | -633 | -6 | 334,568 | ||||
| 2021-02-10 | 2021-02-08 | 4 | Young Richard A | SYRS | Common Stock | D | 13.0400 | -3,750 | -49 | 325,461 | ||||
| 2020-12-21 | 2020-12-18 | 4 | Simonian Nancy A | SYRS | Stock Option (right to buy) | D | 10.09 | -4,988 | 280,012 | |||||
| 2020-12-21 | 2020-12-18 | 4 | Simonian Nancy A | SYRS | Stock Option (right to buy) | D | 8.51 | -14,168 | 79,165 | |||||
| 2020-12-21 | 2020-12-18 | 4 | Simonian Nancy A | SYRS | Stock Option (right to buy) | D | 3.04 | -10,761 | 21,524 | |||||
| 2020-12-21 | 2020-12-18 | 4 | Simonian Nancy A | SYRS | Common Stock | D | 10.0900 | 4,988 | 50 | 563,606 | ||||
| 2020-12-21 | 2020-12-18 | 4 | Simonian Nancy A | SYRS | Common Stock | D | 8.5100 | 14,168 | 121 | 558,618 | ||||
| 2020-12-21 | 2020-12-18 | 4 | Simonian Nancy A | SYRS | Common Stock | D | 3.0400 | 10,761 | 33 | 544,450 | ||||
| 2020-12-11 | 2020-12-08 | 4 | AKKARAJU SRINIVAS | SYRS | Warrants (right to buy) | I | 11.00 | 156,250 | 156,250 | |||||
| 2020-12-11 | 2020-12-08 | 4 | AKKARAJU SRINIVAS | SYRS | Common Stock | I | 625,000 | 1,899,616 | ||||||
| 2020-11-18 | 2020-11-17 | 4 | Young Richard A | SYRS | Common Stock | D | 8.7500 | -5,357 | -47 | 339,211 | ||||
| 2020-11-18 | 2020-11-16 | 4 | Young Richard A | SYRS | Common Stock | D | 8.9800 | -633 | -6 | 344,568 | ||||
| 2020-10-19 | 2020-10-19 | 4 | Young Richard A | SYRS | Common Stock | D | 8.7500 | -5,673 | -50 | 335,201 | ||||
| 2020-10-16 | 2020-10-15 | 4 | Young Richard A | SYRS | Common Stock | D | 8.7500 | -317 | -3 | 340,874 | ||||
| 2020-09-16 | 2020-09-15 | 4 | Young Richard A | SYRS | Common Stock | D | 10.3900 | -5,990 | -62 | 341,191 | ||||
| 2020-09-09 | 2020-09-08 | 4 | Eckhardt Sue Gail | SYRS | Stock Option (right to buy) | D | 8.94 | 35,000 | 35,000 | |||||
| 2020-08-19 | 2020-08-17 | 4 | Young Richard A | SYRS | Common Stock | D | 12.5900 | -5,990 | -75 | 347,181 | ||||
| 2020-08-19 | 2020-08-18 | 4 | Olson Eric R | SYRS | Stock Option (right to buy) | D | 1.01 | -10,787 | 94,325 | |||||
| 2020-08-19 | 2020-08-18 | 4 | Olson Eric R | SYRS | Common Stock | D | 13.0000 | -10,787 | -140 | 0 | ||||
| 2020-08-19 | 2020-08-18 | 4 | Olson Eric R | SYRS | Common Stock | D | 1.0100 | 10,787 | 11 | 10,787 | ||||
| 2020-08-19 | 2020-08-17 | 4 | Olson Eric R | SYRS | Stock Option (right to buy) | D | 1.01 | -4,963 | 105,112 | |||||
| 2020-08-19 | 2020-08-17 | 4 | Olson Eric R | SYRS | Common Stock | D | 13.0000 | -4,963 | -65 | 0 | ||||
| 2020-08-19 | 2020-08-17 | 4 | Olson Eric R | SYRS | Common Stock | D | 1.0100 | 4,963 | 5 | 4,963 | ||||
| 2020-08-19 | 2020-08-18 | 4 | AKKARAJU SRINIVAS | SYRS | Common Stock | I | 13.0955 | -158,583 | -2,077 | 1,274,616 | ||||
| 2020-08-19 | 2020-08-17 | 4 | AKKARAJU SRINIVAS | SYRS | Common Stock | I | 13.0000 | -744 | -10 | 1,433,199 | ||||
| 2020-07-17 | 2020-07-15 | 4 | Young Richard A | SYRS | Common Stock | D | 11.8500 | -5,990 | -71 | 353,171 | ||||
| 2020-07-07 | 2020-07-07 | 4 | Olson Eric R | SYRS | Common Stock | D | 11.7162 | -1,753 | -21 | 0 | ||||
| 2020-07-06 | 2020-07-01 | 4 | AKKARAJU SRINIVAS | SYRS | Common Stock | I | 11.0149 | -4,627 | -51 | 1,433,943 | ||||
| 2020-06-25 | 2020-06-25 | 4 | AKKARAJU SRINIVAS | SYRS | Common Stock | I | 11.1484 | -54,972 | -613 | 1,438,570 | ||||
| 2020-06-25 | 2020-06-24 | 4 | AKKARAJU SRINIVAS | SYRS | Common Stock | I | 11.0669 | -48,775 | -540 | 1,493,542 | ||||
| 2020-06-25 | 2020-06-23 | 4 | AKKARAJU SRINIVAS | SYRS | Common Stock | I | 11.1069 | -50,953 | -566 | 1,542,317 | ||||
| 2020-06-16 | 2020-06-15 | 4 | Young Richard A | SYRS | Common Stock | D | 8.7500 | -5,990 | -52 | 359,161 | ||||
| 2020-06-11 | 2020-06-11 | 4 | SHARP PHILIP A | SYRS | Stock Option (right to buy) | D | 9.17 | 17,500 | 17,500 | |||||
| 2020-06-11 | 2020-06-11 | 4 | WIRTH PETER | SYRS | Stock Option (right to buy) | D | 9.17 | 17,500 | 17,500 | |||||
| 2020-06-11 | 2020-06-11 | 4 | Young Richard A | SYRS | Stock Option (right to buy) | D | 9.17 | 17,500 | 17,500 | |||||
| 2020-06-11 | 2020-06-11 | 4 | AKKARAJU SRINIVAS | SYRS | Stock Option (right to buy) | D | 9.17 | 17,500 | 17,500 | |||||
| 2020-06-11 | 2020-06-11 | 4 | Alles Mark J | SYRS | Stock Option (right to buy) | D | 9.17 | 17,500 | 17,500 | |||||
| 2020-06-11 | 2020-06-11 | 4 | Fanucci Marsha | SYRS | Stock Option (right to buy) | D | 9.17 | 17,500 | 17,500 | |||||
| 2020-06-11 | 2020-06-11 | 4 | Nashat Amir | SYRS | Stock Option (right to buy) | D | 9.17 | 17,500 | 17,500 | |||||
| 2020-05-15 | 2020-05-15 | 4 | Young Richard A | SYRS | Common Stock | D | 9.2224 | -5,990 | -55 | 365,151 | ||||
| 2020-05-13 | 2020-05-13 | 4 | Alles Mark J | SYRS | Common Stock | D | 8.8590 | 10,000 | 89 | 10,000 | ||||
| 2020-04-17 | 2020-04-15 | 4 | Young Richard A | SYRS | Common Stock | D | 8.7500 | -23,960 | -210 | 371,141 | ||||
| 2020-02-20 | 2020-02-18 | 4 | Olson Eric R | SYRS | Common Stock | D | 7.3818 | -1,446 | -11 | 0 | ||||
| 2020-02-14 | 2020-02-13 | 4 | Simonian Nancy A | SYRS | Stock Option (right to buy) | D | 7.54 | 294,000 | 294,000 | |||||
| 2020-02-14 | 2020-02-13 | 4 | Ferra Joseph J Jr | SYRS | Stock Option (right to buy) | D | 7.54 | 94,000 | 94,000 | |||||
| 2020-02-14 | 2020-02-13 | 4 | Olson Eric R | SYRS | Stock Option (right to buy) | D | 7.54 | 94,000 | 94,000 | |||||
| 2020-02-14 | 2020-02-13 | 4 | Quirk Gerald E | SYRS | Stock Option (right to buy) | D | 7.54 | 94,000 | 94,000 | |||||
| 2020-02-14 | 2020-02-13 | 4 | Roth David | SYRS | Stock Option (right to buy) | D | 7.54 | 94,000 | 94,000 | |||||
| 2020-02-14 | 2020-02-13 | 4 | Springhorn Jeremy P. | SYRS | Stock Option (right to buy) | D | 7.54 | 94,000 | 94,000 | |||||
| 2019-12-23 | 2019-12-23 | 4 | Simonian Nancy A | SYRS | Stock Option (right to buy) | D | 3.04 | -8,210 | 1,018,123 | |||||
| 2019-12-23 | 2019-12-23 | 4 | Simonian Nancy A | SYRS | Stock Option (right to buy) | D | 3.04 | -10,762 | 1,026,333 | |||||
| 2019-12-23 | 2019-12-23 | 4 | Simonian Nancy A | SYRS | Stock Option (right to buy) | D | 3.04 | -33,429 | 1,037,095 | |||||
| 2019-12-23 | 2019-12-23 | 4 | Simonian Nancy A | SYRS | Common Stock | D | 3.0400 | 52,401 | 159 | 533,689 | ||||
| 2019-12-20 | 2019-12-19 | 4 | Alles Mark J | SYRS | Stock Option (right to buy) | D | 6.22 | 35,000 | 35,000 | |||||
| 2019-11-12 | 2019-11-12 | 4 | Springhorn Jeremy P. | SYRS | Common Stock | D | 4.9667 | 10,121 | 50 | 35,000 | ||||
| 2019-11-12 | 2019-11-11 | 4 | Springhorn Jeremy P. | SYRS | Common Stock | D | 4.9932 | 9,879 | 49 | 24,879 | ||||
| 2019-08-19 | 2019-08-16 | 4 | Young Richard A | SYRS | Common Stock | D | 10.0000 | -22,700 | -227 | 395,101 | ||||
| 2019-08-19 | 2019-08-15 | 4 | Young Richard A | SYRS | Common Stock | D | 10.0000 | -2,300 | -23 | 417,801 | ||||
| 2019-07-17 | 2019-07-17 | 4 | Arch Venture Fund VII LP | SYRS | Common Stock | D | 7.6964 | -34,521 | -266 | 4,242,051 | ||||
| 2019-07-17 | 2019-07-16 | 4 | Arch Venture Fund VII LP | SYRS | Common Stock | D | 7.8078 | -25,779 | -201 | 4,276,572 | ||||
| 2019-07-17 | 2019-07-15 | 4 | Arch Venture Fund VII LP | SYRS | Common Stock | D | 8.2651 | -2,700 | -22 | 4,302,051 | ||||
| 2019-06-12 | 2019-06-11 | 4 | SHARP PHILIP A | SYRS | Stock Option (right to buy) | D | 5.60 | 11,000 | 11,000 | |||||
| 2019-06-12 | 2019-06-11 | 4 | Shaw Alice Tsang | SYRS | Stock Option (right to buy) | D | 5.60 | 22,000 | 22,000 | |||||
| 2019-06-12 | 2019-06-11 | 4 | WIRTH PETER | SYRS | Stock Option (right to buy) | D | 5.60 | 11,000 | 11,000 | |||||
| 2019-06-12 | 2019-06-11 | 4 | Young Richard A | SYRS | Stock Option (right to buy) | D | 5.60 | 11,000 | 11,000 | |||||
| 2019-06-12 | 2019-06-11 | 4 | AKKARAJU SRINIVAS | SYRS | Stock Option (right to buy) | D | 5.60 | 11,000 | 11,000 | |||||
| 2019-06-12 | 2019-06-11 | 4 | BONNEY MICHAEL W | SYRS | Stock Option (right to buy) | D | 5.60 | 11,000 | 11,000 | |||||
| 2019-06-12 | 2019-06-11 | 4 | Fanucci Marsha | SYRS | Common Stock (right to buy) | D | 5.60 | 11,000 | 11,000 | |||||
| 2019-06-12 | 2019-06-11 | 4 | Nashat Amir | SYRS | Stock Option (right to buy) | D | 5.60 | 11,000 | 11,000 | |||||
| 2019-06-12 | 2019-06-11 | 4 | SATO VICKI L | SYRS | Common Stock (right to buy) | D | 5.60 | 11,000 | 11,000 | |||||
| 2019-04-11 | 2019-04-09 | 4 | AKKARAJU SRINIVAS | SYRS | Common Stock Warrants (rights to buy) | I | 8.62 | 133,333 | 133,333 | |||||
| 2019-04-11 | 2019-04-09 | 4 | AKKARAJU SRINIVAS | SYRS | Common Stock | I | 7.5000 | 533,332 | 4,000 | 1,593,270 | ||||
| 2019-03-14 | 2019-03-14 | 4 | Arch Venture Fund VII LP | SYRS | Common Stock | D | 8.1498 | -43,000 | -350 | 4,305,051 | ||||
| 2019-03-14 | 2019-03-13 | 4 | Arch Venture Fund VII LP | SYRS | Common Stock | D | 8.1993 | -2,820 | -23 | 4,348,051 | ||||
| 2019-03-14 | 2019-03-13 | 4 | Arch Venture Fund VII LP | SYRS | Common Stock | D | 7.8862 | -81,591 | -643 | 4,350,871 | ||||
| 2019-03-14 | 2019-03-12 | 4 | Arch Venture Fund VII LP | SYRS | Common Stock | D | 7.3674 | -40,092 | -295 | 4,432,462 | ||||
| 2019-03-11 | 2019-03-11 | 4 | Arch Venture Fund VII LP | SYRS | Common Stock | D | 6.4924 | -44,878 | -291 | 4,472,554 | ||||
| 2019-03-11 | 2019-03-08 | 4 | Arch Venture Fund VII LP | SYRS | Common Stock | D | 6.9266 | -84,496 | -585 | 4,517,432 | ||||
| 2019-03-11 | 2019-03-07 | 4 | Arch Venture Fund VII LP | SYRS | Common Stock | D | 6.8736 | -35,209 | -242 | 4,601,928 | ||||
| 2019-02-14 | 2019-02-12 | 4 | Ferra Joseph J Jr | SYRS | Stock Option (right to buy) | D | 6.71 | 75,000 | 75,000 | |||||
| 2019-02-14 | 2019-02-12 | 4 | Ferra Joseph J Jr | SYRS | Common Stock | D | 87,000 | 87,000 | ||||||
| 2019-02-14 | 2019-02-12 | 4 | Olson Eric R | SYRS | Stock Option (right to buy) | D | 6.71 | 75,000 | 75,000 | |||||
| 2019-02-14 | 2019-02-12 | 4 | Olson Eric R | SYRS | Common Stock | D | 87,000 | 87,000 | ||||||
| 2019-02-14 | 2019-02-12 | 4 | Quirk Gerald E | SYRS | Stock Option (right to buy) | D | 6.71 | 75,000 | 75,000 | |||||
| 2019-02-14 | 2019-02-12 | 4 | Quirk Gerald E | SYRS | Common Stock | D | 87,000 | 87,000 | ||||||
| 2019-02-14 | 2019-02-12 | 4 | Roth David | SYRS | Stock Option (right to buy) | D | 6.71 | 75,000 | 75,000 | |||||
| 2019-02-14 | 2019-02-12 | 4 | Roth David | SYRS | Common Stock | D | 87,000 | 87,000 | ||||||
| 2019-02-14 | 2019-02-12 | 4 | Simonian Nancy A | SYRS | Stock Option (right to buy) | D | 6.71 | 285,000 | 285,000 | |||||
| 2019-02-14 | 2019-02-12 | 4 | Simonian Nancy A | SYRS | Common Stock | D | 188,000 | 669,288 | ||||||
| 2019-02-14 | 2019-02-12 | 4 | Springhorn Jeremy P. | SYRS | Stock Option (right to buy) | D | 6.71 | 75,000 | 75,000 | |||||
| 2019-02-14 | 2019-02-12 | 4 | Springhorn Jeremy P. | SYRS | Common Stock | D | 87,000 | 102,000 | ||||||
| 2018-12-03 | 2018-11-29 | 4 | Simonian Nancy A | SYRS | Stock Option (right to buy) | D | 3.04 | 12,084 | 785,523 | |||||
| 2018-12-03 | 2018-11-29 | 4 | Simonian Nancy A | SYRS | Stock Option (right to buy) | D | 1.01 | 75,050 | 797,607 | |||||
| 2018-12-03 | 2018-11-29 | 4 | Simonian Nancy A | SYRS | Stock Option (right to buy) | D | 1.01 | 23,454 | 872,657 | |||||
| 2018-12-03 | 2018-11-29 | 4 | Simonian Nancy A | SYRS | Common Stock | D | 3.0400 | 12,084 | 37 | 481,288 | ||||
| 2018-12-03 | 2018-11-29 | 4 | Simonian Nancy A | SYRS | Common Stock | D | 1.0100 | 98,504 | 99 | 469,204 | ||||
| 2018-06-15 | 2018-06-14 | 4 | BONNEY MICHAEL W | SYRS | Stock Option (right to buy) | D | 12.95 | 13,000 | 13,000 | |||||
| 2018-06-15 | 2018-06-14 | 4 | Fanucci Marsha | SYRS | Stock Option (right to buy) | D | 12.95 | 11,000 | 11,000 | |||||
| 2018-06-15 | 2018-06-14 | 4 | Nashat Amir | SYRS | Stock Option (right to buy) | D | 12.95 | 11,000 | 11,000 | |||||
| 2018-06-15 | 2018-06-14 | 4 | SATO VICKI L | SYRS | Stock Option (right to buy) | D | 12.95 | 11,000 | 11,000 | |||||
| 2018-06-15 | 2018-06-14 | 4 | SHARP PHILIP A | SYRS | Stock Option (right to buy) | D | 12.95 | 11,000 | 11,000 | |||||
| 2018-06-15 | 2018-06-14 | 4 | WIRTH PETER | SYRS | Stock Option (right to buy) | D | 12.95 | 11,000 | 11,000 | |||||
| 2018-06-15 | 2018-06-14 | 4 | Young Richard A | SYRS | Stock Option (right to buy) | D | 12.95 | 11,000 | 11,000 | |||||
| 2018-06-15 | 2018-06-14 | 4 | AKKARAJU SRINIVAS | SYRS | Stock Option (right to buy) | D | 12.95 | 11,000 | 11,000 | |||||
| 2018-03-12 | 2018-03-12 | 4 | Ferra Joseph J Jr | SYRS | Stock Option (right to buy) | D | 12.32 | 50,000 | 50,000 | |||||
| 2018-03-12 | 2018-03-12 | 4 | Ferra Joseph J Jr | SYRS | Stock Option (right to buy) | D | 12.32 | 150,000 | 150,000 | |||||
| 2018-02-21 | 2018-02-16 | 4 | Olson Eric R | SYRS | Stock Option (right to buy) | D | 10.09 | 75,000 | 75,000 | |||||
| 2018-02-21 | 2018-02-16 | 4 | Quirk Gerald E | SYRS | Stock Option (right to buy) | D | 13.30 | 11,666 | 11,666 | |||||
| 2018-02-21 | 2018-02-16 | 4 | Quirk Gerald E | SYRS | Stock Option (right to buy) | D | 10.09 | 75,000 | 75,000 | |||||
| 2018-02-21 | 2018-02-16 | 4 | Simonian Nancy A | SYRS | Stock Option (right to buy) | D | 10.09 | 285,000 | 285,000 | |||||
| 2018-02-21 | 2018-02-16 | 4 | Roth David | SYRS | Stock Option (right to buy) | D | 10.09 | 75,000 | 75,000 | |||||
| 2018-02-13 | 2017-09-08 | 5 | AFEYAN NOUBAR | SYRS | Common Stock | D | -24,527 | 0 | ||||||
| 2018-02-02 | 2018-01-31 | 4 | AKKARAJU SRINIVAS see footnote 1 | SYRS | Common Stock | I | 9.5500 | 209,424 | 2,000 | 1,059,938 | ||||
| 2017-12-22 | 3/A | AKKARAJU SRINIVAS By Samsara BioCapital, L.P. | SYRS | Common Stock | I | 740,740 | ||||||||
| 2017-12-15 | 2017-12-15 | 4 | Springhorn Jeremy P. | SYRS | Common Stock | D | 9.0840 | 15,000 | 136 | 15,000 | ||||
| 2017-12-14 | 2017-12-14 | 4 | AKKARAJU SRINIVAS | SYRS | Common Stock | I | 8.9900 | 26,600 | 239 | 830,494 | ||||
| 2017-12-14 | 2017-12-13 | 4 | AKKARAJU SRINIVAS | SYRS | Common Stock | I | 8.9700 | 68,400 | 614 | 803,894 | ||||
| 2017-12-14 | 2017-12-12 | 4 | AKKARAJU SRINIVAS | SYRS | Common Stock | I | 9.4000 | 14,774 | 139 | 735,494 | ||||
| 2017-11-14 | 2017-11-13 | 4 | Springhorn Jeremy P. | SYRS | Stock Option (right to buy) | D | 11.65 | 50,000 | 50,000 | |||||
| 2017-11-14 | 2017-11-13 | 4 | Springhorn Jeremy P. | SYRS | Stock Option (right to buy) | D | 11.65 | 150,000 | 150,000 | |||||
| 2017-10-23 | 2017-10-23 | 4 | DeSimone Colleen Elizabeth | SYRS | Stock Option (right to buy) | D | 3.04 | -550 | 13,016 | |||||
| 2017-10-23 | 2017-10-23 | 4 | DeSimone Colleen Elizabeth | SYRS | Common Stock | D | 16.0605 | -550 | -9 | 0 | ||||
| 2017-10-23 | 2017-10-23 | 4 | DeSimone Colleen Elizabeth | SYRS | Common Stock | D | 3.0400 | 550 | 2 | 550 | ||||
| 2017-09-22 | 2017-06-08 | 4/A | AKKARAJU SRINIVAS | SYRS | Stock Option (right to buy) | D | 14.62 | 22,000 | 22,000 | |||||
| 2017-09-22 | 2017-06-08 | 4/A | Fanucci Marsha | SYRS | Stock Option (right to buy) | D | 14.62 | 11,000 | 11,000 | |||||
| 2017-09-22 | 2017-06-08 | 4/A | Nashat Amir | SYRS | Stock Option (right to buy) | D | 14.62 | 11,000 | 11,000 | |||||
| 2017-09-22 | 2017-06-08 | 4/A | Patel Sanj K | SYRS | Stock Option (right to buy) | D | 14.62 | 11,000 | 11,000 | |||||
| 2017-09-22 | 2017-06-08 | 4/A | SATO VICKI L | SYRS | Stock Option (right to buy) | D | 14.62 | 11,000 | 11,000 | |||||
| 2017-09-22 | 2017-06-08 | 4/A | SHARP PHILIP A | SYRS | Stock Option (right to buy) | D | 14.62 | 11,000 | 11,000 | |||||
| 2017-09-22 | 2017-06-08 | 4/A | Young Richard A | SYRS | Stock Option (right to buy) | D | 14.62 | 11,000 | 11,000 | |||||
| 2017-09-22 | 2017-06-08 | 4/A | NELSEN ROBERT | SYRS | Stock Option (right to buy) | D | 14.62 | 11,000 | 11,000 | |||||
| 2017-08-21 | 2017-08-17 | 4 | Flagship Ventures Fund IV, L.P. | SYRS | Common Stock | I | -54,293 | 0 | ||||||
| 2017-08-21 | 2017-08-17 | 4 | Flagship Ventures Fund IV, L.P. | SYRS | Common Stock | I | -306,222 | 612,442 | ||||||
| 2017-08-21 | 2017-08-17 | 4 | Flagship Ventures Fund IV, L.P. | SYRS | Common Stock | D | -1,295,997 | 2,378,663 | ||||||
| 2017-08-16 | 2017-08-14 | 4 | Young Richard A | SYRS | Common Stock | D | 22.0000 | -3,282 | -72 | 420,101 | ||||
| 2017-08-08 | 2017-08-07 | 4 | Olson Eric R | SYRS | Stock Option (right to buy) | D | 1.01 | 2,500 | 110,075 | |||||
| 2017-08-08 | 2017-08-07 | 4 | Olson Eric R | SYRS | Common Stock | D | 23.5876 | -2,500 | -59 | 0 | ||||
| 2017-08-08 | 2017-08-07 | 4 | Olson Eric R | SYRS | Common Stock | D | 1.0100 | 2,500 | 3 | 2,500 | ||||
| 2017-07-27 | 2017-07-25 | 4 | Young Richard A | SYRS | Common Stock | D | 22.0889 | -3,282 | -72 | 423,383 | ||||
| 2017-07-27 | 2017-07-25 | 4 | Olson Eric R | SYRS | Stock Option (right to buy) | D | 1.01 | 12,500 | 25,025 | |||||
| 2017-07-27 | 2017-07-25 | 4 | Olson Eric R | SYRS | Common Stock | D | 21.8500 | -12,500 | -273 | 0 | ||||
| 2017-07-27 | 2017-07-25 | 4 | Olson Eric R | SYRS | Common Stock | D | 1.0100 | 12,500 | 13 | 12,500 | ||||
| 2017-06-12 | 3 | AKKARAJU SRINIVAS by Samsara BioCapital, L.P. | SYRS | Common Stock | I | 1,441,440 | ||||||||
| 2017-06-12 | 3 | AKKARAJU SRINIVAS by Samsara BioCapital, L.P. | SYRS | Common Stock | I | 1,441,440 | ||||||||
| 2017-06-12 | 2017-06-08 | 4 | Young Richard A | SYRS | Stock Option (right to buy) | D | 14.26 | 11,000 | 11,000 | |||||
| 2017-06-12 | 2017-06-08 | 4 | SHARP PHILIP A | SYRS | Stock Option (right to buy) | D | 14.26 | 11,000 | 11,000 | |||||
| 2017-06-12 | 2017-06-08 | 4 | SATO VICKI L | SYRS | Stock Option (right to buy) | D | 14.26 | 11,000 | 11,000 | |||||
| 2017-06-12 | 2017-06-08 | 4 | NELSEN ROBERT | SYRS | Stock Option (right to buy) | D | 14.26 | 11,000 | 11,000 | |||||
| 2017-06-12 | 2017-06-08 | 4 | Patel Sanj K | SYRS | Stock Option (right to buy) | D | 14.26 | 11,000 | 11,000 | |||||
| 2017-06-12 | 2017-06-08 | 4 | Nashat Amir | SYRS | Stock Option (right to buy) | D | 14.26 | 11,000 | 11,000 | |||||
| 2017-06-12 | 2017-06-08 | 4 | Fanucci Marsha | SYRS | Stock Option (right to buy) | D | 14.26 | 11,000 | 11,000 | |||||
| 2017-06-12 | 2017-06-08 | 4 | AKKARAJU SRINIVAS | SYRS | Stock Option (right to buy) | D | 14.26 | 22,000 | 22,000 | |||||
| 2017-02-13 | 2017-02-09 | 5 | Young Richard A | SYRS | Common Stock | D | -106,667 | 426,665 | ||||||
| 2017-02-13 | 2017-02-10 | 4 | Roth David | SYRS | Stock Option (right to buy) | D | 10.90 | 63,500 | 63,500 | |||||
| 2017-02-13 | 2017-02-10 | 4 | Quirk Gerald E | SYRS | Stock Option (right to buy) | D | 10.90 | 40,000 | 40,000 | |||||
| 2017-02-13 | 2017-02-10 | 4 | Olson Eric R | SYRS | Stock Option (right to buy) | D | 10.90 | 63,500 | 63,500 | |||||
| 2017-02-13 | 2017-02-10 | 4 | Simonian Nancy A | SYRS | Stock Option (right to buy) | D | 10.90 | 175,000 | 175,000 | |||||
| 2017-02-13 | 2017-02-10 | 4 | Kuvalanka Kyle D. | SYRS | Stock Option (right to buy) | D | 10.90 | 78,000 | 78,000 | |||||
| 2017-01-30 | 2017-01-27 | 4 | WIRTH PETER | SYRS | Stock Option (Right to Buy) | D | 10.76 | 22,000 | 22,000 | |||||
| 2016-09-29 | 2016-09-27 | 4 | Quirk Gerald E | SYRS | Stock Option (right to buy) | D | 13.30 | 105,000 | 105,000 | |||||
| 2016-09-19 | 2016-09-15 | 4 | NELSEN ROBERT | SYRS | Stock Option (right to buy) | D | 12.59 | 22,000 | 22,000 | |||||
| 2016-09-19 | 2016-09-15 | 4 | Fanucci Marsha | SYRS | Stock Option (right to buy) | D | 12.59 | 22,000 | 22,000 | |||||
| 2016-09-19 | 2016-09-15 | 4 | Young Richard A | SYRS | Stock Option (right to buy) | D | 12.59 | 22,000 | 22,000 | |||||
| 2016-09-19 | 2016-09-15 | 4 | Bancel Stephane | SYRS | Stock Option (right to buy) | D | 12.59 | 22,000 | 22,000 | |||||
| 2016-09-19 | 2016-09-15 | 4 | SHARP PHILIP A | SYRS | Stock Option (right to buy) | D | 12.59 | 22,000 | 22,000 | |||||
| 2016-09-19 | 2016-09-15 | 4 | Patel Sanj K | SYRS | Stock Option (right to buy) | D | 12.59 | 22,000 | 22,000 | |||||
| 2016-09-19 | 2016-09-15 | 4 | SATO VICKI L | SYRS | Stock Option (right to buy) | D | 12.59 | 22,000 | 22,000 | |||||
| 2016-09-19 | 2016-09-16 | 4 | Simonian Nancy A | SYRS | Stock Option (right to buy) | D | 12.17 | 75,000 | 75,000 | |||||
| 2016-09-19 | 2016-09-15 | 4 | Nashat Amir | SYRS | Stock Option (right to buy) | D | 12.59 | 22,000 | 22,000 | |||||
| 2016-07-07 | 2016-07-06 | 4 | Arch Venture Fund VII LP | SYRS | Series B Preferred Stock | D | -1,589,269 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Arch Venture Fund VII LP | SYRS | Series A-3 Preferred Stock | D | -7,500,000 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Arch Venture Fund VII LP | SYRS | Series A-2 Preferred Stock | D | -5,000,000 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Arch Venture Fund VII LP | SYRS | Series A-1 Preferred Stock | D | -1,000,000 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Arch Venture Fund VII LP | SYRS | Common Stock | D | 12.5000 | 400,000 | 5,000 | 4,637,137 | ||||
| 2016-07-07 | 2016-07-06 | 4 | Arch Venture Fund VII LP | SYRS | Common Stock | D | 423,805 | 4,237,137 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Arch Venture Fund VII LP | SYRS | Common Stock | D | 2,000,000 | 3,813,332 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Arch Venture Fund VII LP | SYRS | Common Stock | D | 1,333,333 | 1,813,332 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Arch Venture Fund VII LP | SYRS | Common Stock | D | 266,666 | 479,999 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Nashat Amir | SYRS | Series B Preferred Stock | I | -83,129 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Nashat Amir | SYRS | Series B Preferred Stock | I | -4,366,825 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Nashat Amir | SYRS | Common Stock | I | 12.5000 | 26,153 | 327 | 48,320 | ||||
| 2016-07-07 | 2016-07-06 | 4 | Nashat Amir | SYRS | Common Stock | I | 12.5000 | 373,847 | 4,673 | 1,538,333 | ||||
| 2016-07-07 | 2016-07-06 | 4 | Nashat Amir | SYRS | Common Stock | I | 22,167 | 22,167 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Nashat Amir | SYRS | Common Stock | I | 1,164,486 | 1,164,486 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Flagship Ventures Fund IV, L.P. | SYRS | Series B Preferred Stock | I | -444,995 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Flagship Ventures Fund IV, L.P. | SYRS | Series B Preferred Stock | I | -1,779,981 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Flagship Ventures Fund IV, L.P. | SYRS | Series A-3 Preferred Stock | I | -1,500,000 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Flagship Ventures Fund IV, L.P. | SYRS | Series A-3 Preferred Stock | I | -6,000,000 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Flagship Ventures Fund IV, L.P. | SYRS | Series A-2 Preferred Stock | I | -1,000,000 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Flagship Ventures Fund IV, L.P. | SYRS | Series A-2 Preferred Stock | I | -4,000,000 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Flagship Ventures Fund IV, L.P. | SYRS | Series A-1 Preferred Stock | I | -200,000 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Flagship Ventures Fund IV, L.P. | SYRS | Series A-1 Preferred Stock | I | -800,000 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Flagship Ventures Fund IV, L.P. | SYRS | Common Stock | I | 12.5000 | 80,000 | 1,000 | 918,664 | ||||
| 2016-07-07 | 2016-07-06 | 4 | Flagship Ventures Fund IV, L.P. | SYRS | Common Stock | I | 12.5000 | 320,000 | 4,000 | 3,674,660 | ||||
| 2016-07-07 | 2016-07-06 | 4 | Flagship Ventures Fund IV, L.P. | SYRS | Common Stock | I | 118,665 | 838,664 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Flagship Ventures Fund IV, L.P. | SYRS | Common Stock | I | 474,661 | 3,354,660 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Flagship Ventures Fund IV, L.P. | SYRS | Common Stock | I | 400,000 | 719,999 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Flagship Ventures Fund IV, L.P. | SYRS | Common Stock | I | 1,600,000 | 2,879,999 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Flagship Ventures Fund IV, L.P. | SYRS | Common Stock | I | 266,666 | 319,999 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Flagship Ventures Fund IV, L.P. | SYRS | Common Stock | I | 1,066,666 | 1,279,999 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Flagship Ventures Fund IV, L.P. | SYRS | Common Stock | I | 53,333 | 53,333 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Flagship Ventures Fund IV, L.P. | SYRS | Common Stock | I | 213,333 | 213,333 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Redmile Group, LLC | SYRS | Series B Preferred Stock | D | -151,576 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Redmile Group, LLC | SYRS | Series B Preferred Stock | D | -117,931 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Redmile Group, LLC | SYRS | Series B Preferred Stock | D | -982,762 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Redmile Group, LLC | SYRS | Series B Preferred Stock | D | -178,074 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Redmile Group, LLC | SYRS | Series B Preferred Stock | D | -317,853 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Redmile Group, LLC | SYRS | Common Stock | D | 12.5000 | 9,373 | 117 | 49,793 | ||||
| 2016-07-07 | 2016-07-06 | 4 | Redmile Group, LLC | SYRS | Common Stock | D | 12.5000 | 174,320 | 2,179 | 205,767 | ||||
| 2016-07-07 | 2016-07-06 | 4 | Redmile Group, LLC | SYRS | Common Stock | D | 12.5000 | 104,670 | 1,308 | 366,739 | ||||
| 2016-07-07 | 2016-07-06 | 4 | Redmile Group, LLC | SYRS | Common Stock | D | 12.5000 | 144,383 | 1,805 | 191,869 | ||||
| 2016-07-07 | 2016-07-06 | 4 | Redmile Group, LLC | SYRS | Common Stock | D | 40,420 | 40,420 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Redmile Group, LLC | SYRS | Common Stock | D | 31,447 | 31,447 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Redmile Group, LLC | SYRS | Common Stock | D | 262,069 | 262,069 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Redmile Group, LLC | SYRS | Common Stock | D | 47,486 | 47,486 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Redmile Group, LLC | SYRS | Common Stock | D | 84,760 | 84,760 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | WuXi PharmTech Healthcare Fund I L.P. | SYRS | Series B Preferred Stock | D | -1,994,471 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | WuXi PharmTech Healthcare Fund I L.P. | SYRS | Series A-3 Preferred Stock | D | -500,000 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | WuXi PharmTech Healthcare Fund I L.P. | SYRS | Series A-1 Preferred Stock | D | -500,000 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | WuXi PharmTech Healthcare Fund I L.P. | SYRS | Series A-2 Preferred Stock | D | -500,000 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | WuXi PharmTech Healthcare Fund I L.P. | SYRS | Common Stock | D | 531,858 | 931,857 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | WuXi PharmTech Healthcare Fund I L.P. | SYRS | Common Stock | D | 133,333 | 399,999 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | WuXi PharmTech Healthcare Fund I L.P. | SYRS | Common Stock | D | 133,333 | 399,999 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | WuXi PharmTech Healthcare Fund I L.P. | SYRS | Common Stock | D | 133,333 | 399,999 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Polaris Management Co. VII, L.L.C. | SYRS | Series B Preferred Stock | I | -83,129 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Polaris Management Co. VII, L.L.C. | SYRS | Series B Preferred Stock | I | -4,366,825 | 0 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Polaris Management Co. VII, L.L.C. | SYRS | Common Stock | I | 12.5000 | 26,153 | 327 | 48,320 | ||||
| 2016-07-07 | 2016-07-06 | 4 | Polaris Management Co. VII, L.L.C. | SYRS | Common Stock | I | 12.5000 | 373,847 | 4,673 | 1,538,333 | ||||
| 2016-07-07 | 2016-07-06 | 4 | Polaris Management Co. VII, L.L.C. | SYRS | Common Stock | I | 22,167 | 22,167 | ||||||
| 2016-07-07 | 2016-07-06 | 4 | Polaris Management Co. VII, L.L.C. | SYRS | Common Stock | I | 1,164,486 | 1,164,486 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | AISLING CAPITAL III LP | SYRS | Series B Preferred Stock | D | -1,907,122 | 0 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | AISLING CAPITAL III LP | SYRS | Common Stock | D | 12.5000 | 400,000 | 5,000 | 908,565 | ||||
| 2016-07-06 | 2016-07-06 | 4 | AISLING CAPITAL III LP | SYRS | Common Stock | D | 508,565 | 508,565 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | NELSEN ROBERT | SYRS | Series B Preferred Stock | I | -1,589,269 | 0 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | NELSEN ROBERT | SYRS | Series A-3 Preferred Stock | I | -7,500,000 | 0 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | NELSEN ROBERT | SYRS | Series A-2 Preferred Stock | I | -5,000,000 | 0 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | NELSEN ROBERT | SYRS | Series A-1 Preferred Stock | I | -1,000,000 | 0 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | NELSEN ROBERT | SYRS | Common Stock | I | 12.5000 | 400,000 | 5,000 | 4,637,137 | ||||
| 2016-07-06 | 2016-07-06 | 4 | NELSEN ROBERT | SYRS | Common Stock | I | 423,805 | 4,237,137 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | NELSEN ROBERT | SYRS | Common Stock | I | 2,000,000 | 3,813,332 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | NELSEN ROBERT | SYRS | Common Stock | I | 1,333,333 | 1,813,332 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | NELSEN ROBERT | SYRS | Common Stock | I | 266,666 | 479,999 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | Simonian Nancy A | SYRS | Series A-2 Preferred Stock | D | -250,000 | 0 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | Simonian Nancy A | SYRS | Common Stock | D | 66,666 | 370,702 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | SHARP PHILIP A | SYRS | Series A-2 Preferred Stock | I | -150,000 | 0 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | SHARP PHILIP A | SYRS | Series A-2 Preferred Stock | I | -150,000 | 0 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | SHARP PHILIP A | SYRS | Series A-2 Preferred Stock | I | -150,000 | 0 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | SHARP PHILIP A | SYRS | Series A-2 Preferred Stock | D | -550,000 | 0 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | SHARP PHILIP A | SYRS | Common Stock | I | 40,000 | 40,000 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | SHARP PHILIP A | SYRS | Common Stock | I | 40,000 | 40,000 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | SHARP PHILIP A | SYRS | Common Stock | I | 40,000 | 40,000 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | SHARP PHILIP A | SYRS | Common Stock | D | 146,666 | 146,666 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | Bancel Stephane | SYRS | Series A-2 Preferred Stock | D | -100,000 | 0 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | Bancel Stephane | SYRS | Common Stock | D | 26,666 | 47,980 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | Flynn James E Through Deerfield Special Situations Fund, L.P. | SYRS | Series B Convertible Preferred Stock | I | -508,566 | 0 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | Flynn James E Through Deerfield Private Design Fund III, L.P. | SYRS | Series B Convertible Preferred Stock | I | -1,186,654 | 0 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | Flynn James E Through Deerfield Special Situations Fund, L.P. | SYRS | Common Stock | I | 12.5000 | 120,000 | 1,500 | 628,566 | ||||
| 2016-07-06 | 2016-07-06 | 4 | Flynn James E Through Deerfield Private Design Fund III, L.P. | SYRS | Common Stock | I | 12.5000 | 280,000 | 3,500 | 1,466,654 | ||||
| 2016-07-06 | 2016-07-06 | 4 | Flynn James E Through Deerfield Special Situations Fund, L.P. | SYRS | Common Stock | I | 508,566 | 508,566 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | Flynn James E Through Deerfield Private Design Fund III, L.P. | SYRS | Common Stock | I | 1,186,654 | 1,186,654 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | WuXi Healthcare Ventures II, L.P. | SYRS | Series B Preferred Stock | D | -1,589,269 | 0 | ||||||
| 2016-07-06 | 2016-07-06 | 4 | WuXi Healthcare Ventures II, L.P. | SYRS | Common Stock | D | 423,805 | 423,805 | ||||||
| 2016-06-29 | 3 | Gray Nathanael | SYRS | Common Stock | D | 853,332 | ||||||||
| 2016-06-29 | 3 | Gray Nathanael | SYRS | Common Stock | D | 853,332 | ||||||||
| 2016-06-29 | 3 | JEB Syros Trust | SYRS | Common Stock | D | 703,332 | ||||||||
| 2016-06-29 | 3 | JEB Syros Trust | SYRS | Common Stock | D | 703,332 | ||||||||
| 2016-06-29 | 3 | Bancel Stephane | SYRS | Common Stock | D | 42,628 | ||||||||
| 2016-06-29 | 3 | Bancel Stephane | SYRS | Common Stock | D | 42,628 | ||||||||
| 2016-06-29 | 3 | Simonian Nancy A | SYRS | Common Stock | D | 768,072 | ||||||||
| 2016-06-29 | 3 | Simonian Nancy A By the Douglas and Nancy Cole Family Trust f/b/o William H. Cole | SYRS | Common Stock | I | 544,036 | ||||||||
| 2016-06-29 | 3 | Simonian Nancy A By the Douglas and Nancy Cole Family Trust f/b/o Bennett H. Cole | SYRS | Common Stock | I | 544,036 | ||||||||
| 2016-06-29 | 3 | Simonian Nancy A By the Douglas and Nancy Cole Family Trust f/b/o William H. Cole | SYRS | Common Stock | I | 544,036 | ||||||||
| 2016-06-29 | 3 | Simonian Nancy A By the Douglas and Nancy Cole Family Trust f/b/o Bennett H. Cole | SYRS | Common Stock | I | 544,036 | ||||||||
| 2016-06-29 | 3 | Simonian Nancy A | SYRS | Common Stock | D | 768,072 | ||||||||
| 2016-06-29 | 3 | KANIA EDWIN M JR | SYRS | Common Stock | I | 426,664 | ||||||||
| 2016-06-29 | 3 | KANIA EDWIN M JR | SYRS | Common Stock | I | 426,664 | ||||||||
| 2016-06-29 | 3 | KANIA EDWIN M JR | SYRS | Common Stock | I | 426,664 | ||||||||
| 2016-06-29 | 3 | KANIA EDWIN M JR | SYRS | Common Stock | I | 426,664 | ||||||||
| 2016-06-29 | 3 | KANIA EDWIN M JR | SYRS | Common Stock | I | 426,664 | ||||||||
| 2016-06-29 | 3 | KANIA EDWIN M JR | SYRS | Common Stock | I | 426,664 | ||||||||
| 2016-06-29 | 3 | KANIA EDWIN M JR | SYRS | Common Stock | I | 426,664 | ||||||||
| 2016-06-29 | 3 | NELSEN ROBERT Shares held by ARCH Venture Fund VII, L.P. | SYRS | Common Stock | I | 426,666 | ||||||||
| 2016-06-29 | 3 | NELSEN ROBERT Shares held by ARCH Venture Fund VII, L.P. | SYRS | Common Stock | I | 426,666 | ||||||||
| 2016-06-29 | 3 | Perspecta Trust LLC Owned by the JEB Syros Trust, of which Perspecta Trust LLC is trustee. | SYRS | Common Stock | I | 703,332 | ||||||||
| 2016-06-29 | 3 | Perspecta Trust LLC Owned by the JEB Syros Trust, of which Perspecta Trust LLC is trustee. | SYRS | Common Stock | I | 703,332 | ||||||||
| 2016-06-29 | 3 | BYBEE CLINTON | SYRS | Common Stock | D | 426,666 | ||||||||
| 2016-06-29 | 3 | BYBEE CLINTON | SYRS | Common Stock | D | 426,666 | ||||||||
| 2016-06-29 | 3 | BYBEE CLINTON | SYRS | Common Stock | D | 426,666 | ||||||||
| 2016-06-29 | 3 | BYBEE CLINTON | SYRS | Common Stock | D | 426,666 | ||||||||
| 2016-06-29 | 3 | BYBEE CLINTON | SYRS | Common Stock | D | 426,666 | ||||||||
| 2016-06-29 | 3 | BYBEE CLINTON | SYRS | Common Stock | D | 426,666 | ||||||||
| 2016-06-29 | 3 | Young Richard A | SYRS | Common Stock | D | 1,066,664 | ||||||||
| 2016-06-29 | 3 | Young Richard A | SYRS | Common Stock | D | 1,066,664 |
P
Pembelian sekuritas non-derivatif atau derivatif di pasar terbuka atau secara pribadi.
S
Penjualan terbuka atau penjualan pribadi atas sekuritas non-derivatif atau derivatif.
A
Hibah, penghargaan, atau perolehan sekuritas lainnya dari perusahaan (seperti opsi)
C
Konversi turunan
D
Penjualan atau pengalihan sekuritas kembali ke perusahaan.
F
Pembayaran harga pelaksanaan atau kewajiban pajak menggunakan sebagian sekuritas yang diterima dari perusahaan.
G
Pemberian sekuritas oleh atau kepada orang dalam.
K
Swap ekuitas dan transaksi lindung nilai serupa
M
Pelaksanaan atau konversi sekuritas derivatif yang diterima dari perusahaan (seperti opsi)
V
Transaksi yang dilaporkan secara sukarela pada Formulir 4.
J
Lainnya (disertai dengan catatan kaki yang menjelaskan transaksi tersebut)
