AUTL / Autolus Therapeutics plc - Depositary Receipt (Common Stock) - Pengajuan SECLaporan Tahunan, Pernyataan Proksi

Autolus Therapeutics plc - Depositary Receipt (Common Stock)
US ˙ NasdaqGS ˙ US05280R1005

Mga Batayang Estadistika
LEI 549300C0KZP8EYROLL02
CIK 1730463
SEC Filings
All companies that sell securities in the United States must register with the Securities and Exchange Commission (SEC) and file reports on a regular basis. These reports include company annual reports (10K, 10Q), news updates (8K), investor presentations (found in 8Ks), insider trades (form 4), ownership reports (13D, and 13G), and reports related to the specific securities sold, such as registration statements and prospectus. This page shows recent SEC filings related to Autolus Therapeutics plc - Depositary Receipt (Common Stock)
SEC Filings (Chronological Order)
Halaman ini menyediakan daftar lengkap dan kronologis dari Pengajuan SEC, tidak termasuk pengajuan kepemilikan yang kami sediakan di tempat lain.
August 12, 2025 EX-10.1

Autolus Therapeutics plc - 2025 Employee Share Purchase Plan

ex-101xautolustherapeuti 303197006 v5 Exhibit 10.1 AUTOLUS THERAPEUTICS PLC 2025 EMPLOYEE SHARE PURCHASE PLAN ADOPTED BY THE BOARD OF DIRECTORS: MAY 20, 2025 APPROVED BY THE SHAREHOLDERS: JUNE 26, 2025 1. GENERAL; PURPOSE. (a) The Plan provides a means by which Eligible Employees of the Company and certain Designated Companies may be given an opportunity to purchase Shares. The Plan permits the Co

August 12, 2025 EX-99.1

Autolus Therapeutics Reports Second Quarter 2025 Financial Results and Business Updates August 12, 2025 at 7:00 AM EDT Company reports Q2 2025 AUCATZYL® net product revenue of $20.9 million and $29.9 for the first six months of 2025 Company recently

autlex-991pr120825 Autolus Therapeutics Reports Second Quarter 2025 Financial Results and Business Updates August 12, 2025 at 7:00 AM EDT Company reports Q2 2025 AUCATZYL® net product revenue of $20.

August 12, 2025 EX-10.1

Autolus Therapeutics plc - 2025

ex-101xautolustherapeuti 303197006 v5 Exhibit 10.1 AUTOLUS THERAPEUTICS PLC 2025 EMPLOYEE SHARE PURCHASE PLAN ADOPTED BY THE BOARD OF DIRECTORS: MAY 20, 2025 APPROVED BY THE SHAREHOLDERS: JUNE 26, 2025 1. GENERAL; PURPOSE. (a) The Plan provides a means by which Eligible Employees of the Company and certain Designated Companies may be given an opportunity to purchase Shares. The Plan permits the Co

August 12, 2025 EX-99.2

Q2 2025 Financial Results and Business Updates August 12, 2025 Autolus.com For Investor communication only. Not for use in product promotion. Not for further distribution. EX-99.2 Disclaimer These slides contain forward-looking statements within the

autlex-992cp120825 Q2 2025 Financial Results and Business Updates August 12, 2025 Autolus.

August 12, 2025 EX-10.2

Autolus Therapeutics plc - 2025

ex-102xautolustherapeuti Exhibit 10.2 AUTOLUS THERAPEUTICS PLC UK SHARESAVE SUB-PLAN TO THE AUTOLUS THERAPEUTICS PLC 2025 EMPLOYEE SHARE PURCHASE PLAN Adopted by the Board on May 20, 2025 Registered with HM Revenue & Customs on under number . CONTENTS Clause Page 1. INTERPRETATION.......................................................................................................................

August 12, 2025 EX-10.2

Autolus Therapeutics plc - 2025 UK Sharesave Sub-plan

ex-102xautolustherapeuti Exhibit 10.2 AUTOLUS THERAPEUTICS PLC UK SHARESAVE SUB-PLAN TO THE AUTOLUS THERAPEUTICS PLC 2025 EMPLOYEE SHARE PURCHASE PLAN Adopted by the Board on May 20, 2025 Registered with HM Revenue & Customs on under number . CONTENTS Clause Page 1. INTERPRETATION.......................................................................................................................

August 12, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 12, 2025 Autolus Therapeut

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 12, 2025 Autolus Therapeutics plc (Exact name of registrant as specified in its Charter) England and Wales 001-38547 Not applicable (State or other jurisdiction of incorporatio

August 12, 2025 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

Table of contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2025 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number 001

August 12, 2025 424B3

Up to 54,584,250 American Depositary Shares Representing 54,584,250 Ordinary Shares Offered by Selling Securityholders

Table of contents Filed pursuant to Rule 424(b)(3) Registration No. 333-287097 PROSPECTUS SUPPLEMENT NO. 3 (To the prospectus dated May 15, 2025) Up to 54,584,250 American Depositary Shares Representing 54,584,250 Ordinary Shares Offered by Selling Securityholders This prospectus supplement supplements the prospectus, dated May 15, 2025 (the “Prospectus”), which forms a part of our registration st

June 30, 2025 424B3

Up to 54,584,250 American Depositary Shares Representing 54,584,250 Ordinary Shares Offered by Selling Securityholders

Filed pursuant to Rule 424(b)(3) Registration No. 333-287097 PROSPECTUS SUPPLEMENT NO. 2 (To the prospectus dated May 15, 2025) Up to 54,584,250 American Depositary Shares Representing 54,584,250 Ordinary Shares Offered by Selling Securityholders This prospectus supplement supplements the prospectus, dated May 15, 2025 (the “Prospectus”), which forms a part of our registration statement on Form S-

June 27, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 26, 2025 Autolus Therapeutic

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 26, 2025 Autolus Therapeutics plc (Exact name of registrant as specified in its Charter) England and Wales 001-38547 Not applicable (State or other jurisdiction of incorporation

June 2, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 2, 2025 Autolus Therapeutics

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 2, 2025 Autolus Therapeutics plc (Exact name of registrant as specified in its Charter) England and Wales 001-38547 Not applicable (State or other jurisdiction of incorporation o

June 2, 2025 EX-99.3

Form of Proxy - Annual General Meeting to be held on 26 June 2025 Kindly Note: This form is issued only to the addressee(s) and is specific to the unique designated account printed hereon. This personalised form is not transferable between different:

Form of Proxy - Annual General Meeting to be held on 26 June 2025 Kindly Note: This form is issued only to the addressee(s) and is specific to the unique designated account printed hereon.

June 2, 2025 EX-99.1

statement of liabilities parent company

statement of liabilities parent company

June 2, 2025 EX-99.2

1 THIS DOCUMENT IS IMPORTANT AND REQUIRES YOUR IMMEDIATE ATTENTION. If you are in any doubt as to the action to be taken, please seek your own independent financial advice from your stockbroker, solicitor, accountant or other appropriately authorised

1 THIS DOCUMENT IS IMPORTANT AND REQUIRES YOUR IMMEDIATE ATTENTION. If you are in any doubt as to the action to be taken, please seek your own independent financial advice from your stockbroker, solicitor, accountant or other appropriately authorised independent financial adviser. If you have recently sold or transferred all of your ordinary shares in Autolus Therapeutics plc, you should forward t

May 30, 2025 424B3

Up to 54,584,250 American Depositary Shares Representing 54,584,250 Ordinary Shares Offered by Selling Securityholders

Filed pursuant to Rule 424(b)(3) Registration No. 333-287097 PROSPECTUS SUPPLEMENT NO. 1 (To the prospectus dated May 15, 2025) Up to 54,584,250 American Depositary Shares Representing 54,584,250 Ordinary Shares Offered by Selling Securityholders This prospectus supplement supplements the prospectus, dated May 15, 2025 (the “Prospectus”), which forms a part of our registration statement on Form S-

May 30, 2025 8-K

Current Report

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 23, 2025 Autolus Therapeutics plc (Exact name of registrant as specified in its Charter) England and Wales 001-38547 Not applicable (State or other jurisdiction of incorporation o

May 15, 2025 424B3

Up to 54,584,250 American Depositary Shares Representing 54,584,250 Ordinary Shares

424B3 Table of Contents Filed pursuant to Rule 424(b)(3) File No. 333-287097 Up to 54,584,250 American Depositary Shares Representing 54,584,250 Ordinary Shares This prospectus relates to the resale from time to time by the selling securityholders identified in this prospectus, of up to 54,584,250 American Depositary Shares, or ADSs, consisting of (i) 51,318,944 ADSs, representing 51,318,944 of ou

May 13, 2025 CORRESP

The MediaWorks 191 Wood Lane White City London W12 7FP United Kingdom VIA EDGAR

CORRESP The MediaWorks 191 Wood Lane White City London W12 7FP United Kingdom VIA EDGAR May 13, 2025 U.

May 8, 2025 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

Table of contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2025 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number 00

May 8, 2025 EX-99.2

Q1 2025 Financial Results and Business Updates May 8, 2025 Autolus.com For Investor communication only. Not for use in product promotion. Not for further distribution. Ex-99.2 Disclaimer These slides contain forward-looking statements within the mean

autlex-992cp080525 Q1 2025 Financial Results and Business Updates May 8, 2025 Autolus.

May 8, 2025 EX-FILING FEES

Filing Fee Table

EX-FILING FEES Exhibit 107 Calculation of Filing Fee Tables Form S-1 (Form Type) Autolus Therapeutics plc (Exact Name of Registrant as Specified in its Charter) Table 1 – Newly Registered and Carry Forward Securities Security Type Security Class Title Fee Calculation or Carry Forward Rule Amount Registered Proposed Maximum  Offering Price Per Unit Maximum Aggregate Offering Price Fee Rate  Amount

May 8, 2025 S-1

As filed with the Securities and Exchange Commission on May 8, 2025

S-1 Table of Contents As filed with the Securities and Exchange Commission on May 8, 2025 Registration No.

May 8, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 8, 2025 Autolus Therapeutics

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 8, 2025 Autolus Therapeutics plc (Exact name of registrant as specified in its Charter) England and Wales 001-38547 Not applicable (State or other jurisdiction of incorporation or

May 8, 2025 EX-10.2

Form of Stock Option Grant Notice and Stock Option Agreement for the Autolus Therapeutics plc - 2025 Inducement Plan.

Exhibit 10.2 AUTOLUS THERAPEUTICS PLC OPTION GRANT NOTICE (2025 INDUCEMENT PLAN) Autolus Therapeutics plc (the “Company”), pursuant to its 2025 Inducement Plan (the “Plan”), hereby grants to Optionholder the option described in this grant notice at the exercise price set forth below (the “Option”). This Option is subject to all of the terms and conditions as set forth in this Option Grant Notice (

May 8, 2025 EX-10.3

Form of Restricted Stock Unit Grant Notice and Award Agreement for the Autolus Therapeutics plc - 2025 Inducement

Exhibit 10.3 AUTOLUS THERAPEUTICS PLC RESTRICTED SHARE UNIT GRANT NOTICE (2025 INDUCEMENT PLAN) Autolus Therapeutics plc (the “Company”), pursuant to Section 6(b) of the Company’s 2025 Inducement Plan (the “Plan”), hereby awards to Participant Restricted Share Units (“RSUs” or “Restricted Share Units”) described below (sometimes referred to as the “Award”). The Award is subject to all of the terms

May 8, 2025 EX-99.1

Autolus Therapeutics Reports First Quarter 2025 Financial Results and Business Updates May 8, 2025 at 7:00 AM EDT Company reports Q1 2025 AUCATZYL® net product revenue of $9.0 million U.K. Medicines and Healthcare products Regulatory Agency (MHRA) gr

autlex-991pr080525 Autolus Therapeutics Reports First Quarter 2025 Financial Results and Business Updates May 8, 2025 at 7:00 AM EDT Company reports Q1 2025 AUCATZYL® net product revenue of $9.

May 8, 2025 EX-10.1

utolus Therapeutics plc - 2025 In

Exhibit 10.1 Autolus Therapeutics plc 2025 Inducement Plan Adopted by the Board: March 27, 2025 1.General. (a)Eligible Award Recipients. The only persons eligible to receive grants of Awards under this Plan are individuals who satisfy the standards for inducement grants under Nasdaq Marketplace Rule 5635(c)(4) or 5635(c)(3), if applicable, and the related guidance under Nasdaq IM 5635-1. A person

April 23, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 23, 2025 Autolus Therapeuti

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 23, 2025 Autolus Therapeutics plc (Exact name of registrant as specified in its Charter) England and Wales 001-38547 Not applicable (State or other jurisdiction of incorporation

April 3, 2025 8-K

Current Report

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 28, 2025 Autolus Therapeutics plc (Exact name of registrant as specified in its Charter) England and Wales 001-38547 Not applicable (State or other jurisdiction of incorporat

March 20, 2025 EX-99.1

Exhibit 99.1 1 Autolus Therapeutics Reports Fourth Quarter and Full Year 2024 Financial Results and Business Updates • AUCATZYL® (obecabtagene autoleucel) U.S. commercial launch progressing on track with 33 authorized treatment centers as of March 19

autlex-991pr200325 Exhibit 99.1 1 Autolus Therapeutics Reports Fourth Quarter and Full Year 2024 Financial Results and Business Updates • AUCATZYL® (obecabtagene autoleucel) U.S. commercial launch progressing on track with 33 authorized treatment centers as of March 19, 2025, following US FDA approval on November 8, 2024 • Obe-cel MHRA and EMA marketing authorizations expected in H2 2025 • Initial

March 20, 2025 EX-21.1

Subsidiaries of the registrant.

Exhibit 21.1 Autolus Therapeutics plc List of Subsidiaries Subsidiary Jurisdiction Autolus Holdings (UK) Limited England and Wales Autolus Limited England and Wales Autolus Inc. Delaware Autolus GmbH Germany Autolus Switzerland AG Switzerland

March 20, 2025 EX-99.2

Q4 2024 Financial Results and Business Updates 20 March 2025 Autolus.com For Investor communication only. Not for use in product promotion. Not for further distribution. Exhibit 99.2 Disclaimer These slides contain forward-looking statements within t

Q4 2024 Financial Results and Business Updates 20 March 2025 Autolus.com For Investor communication only. Not for use in product promotion. Not for further distribution. Exhibit 99.2 Disclaimer These slides contain forward-looking statements within the meaning of the “safe harbor” provisions of the Private Securities Litigation Reform Act of 1995. Forward-looking statements are statements that are

March 20, 2025 EX-19.1

Amended and Restated Insider Trading and Window Period Policy

exhibit191-insidertradin 1. 180019795 v1 AUTOLUS THERAPEUTICS PLC INSIDER TRADING AND WINDOW PERIOD POLICY (REVISED OCTOBER 16, 2020) INTRODUCTION During the course of your relationship with AUTOLUS THERAPEUTICS PLC (“Autolus”), you may receive important information that is not yet publicly available (“inside information”) about Autolus or other publicly traded companies that Autolus has business

March 20, 2025 POS AM

As filed with the Securities and Exchange Commission on March 20, 2025

POS AM Table of Contents As filed with the Securities and Exchange Commission on March 20, 2025 Registration No.

March 20, 2025 POSASR

As filed with the Securities and Exchange Commission on March 20, 2025

Table of Contents As filed with the Securities and Exchange Commission on March 20, 2025 Registration No.

March 20, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 20, 2025 Autolus Therapeuti

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 20, 2025 Autolus Therapeutics plc (Exact name of registrant as specified in its Charter) England and Wales 001-38547 Not applicable (State or other jurisdiction of incorporation

March 20, 2025 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K x ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2024 o TRANSITION REPORT PURSUANT TO SECTI

Table of contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K x ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2024 OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 for the transition period from to Commission file number: 001-38547 Autolus

March 20, 2025 EX-FILING FEES

Filing Fee Table

Exhibit 107 Calculation of Filing Fee Tables Form S-3 (Form Type) Autolus Therapeutics plc (Exact Name of Registrant as Specified in its Charter) Table 1 – Newly Registered Securities Security Type Security Class Title Fee Calculation Rule Amount Registered(1) Proposed Maximum Offering Price Per Unit Maximum Aggregate Offering Price Fee Rate Amount of Registration Fee Fees to be Paid Equity Ordinary shares, nominal value $0.

March 20, 2025 EX-10.20

Amended Management Incentive Compensation Plan

exhibit1020-armanagement Exhibit 10.20 1 Management Incentive Compensation Plan (effective March 1, 2025) 1. Purpose of the Plan The Management Incentive Compensation Plan (the “Plan”) of Autolus Therapeutics plc and its group companies (collectively, “Autolus”) is designed to offer incentive compensation to officers and managers of Autolus (the “Associates”) by rewarding the achievement of corpor

March 20, 2025 EX-10.21

Exclusive Distribution Agreement, effective as of

exhibit1021-cardinalheal Exhibit 10.21 P a g e | 1 This document is confidential. Disclosure to third parties not permitted. Autolus/Cardinal Health: Distribution Services Agreement This Distribution Services Agreement (together with all attached Exhibits, the “Agreement”), effective as of the last date of signature (the “Effective Date”), is entered into by and between: 1) Autolus, Inc. with offi

January 13, 2025 EX-99.1

Developing Next Generation Programmed T Cell Therapies January 2025 Autolus.com Disclaimer These slides contain forward-looking statements within the meaning of the “safe harbor” provisions of the Private Securities Litigation Reform Act of 1995. For

Developing Next Generation Programmed T Cell Therapies January 2025 Autolus.com Disclaimer These slides contain forward-looking statements within the meaning of the “safe harbor” provisions of the Private Securities Litigation Reform Act of 1995. Forward-looking statements are statements that are not historical facts, and in some cases can be identified by terms such as “may,” “will,” “could,” “ex

January 13, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 13, 2025 Autolus Therapeu

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 13, 2025 Autolus Therapeutics plc (Exact name of registrant as specified in its Charter) England and Wales 001-38547 Not applicable (State or other jurisdiction of incorporati

November 14, 2024 EX-99.1

AGREEMENT

EX-99.1 2 d901415dex991.htm EX-99.1 Exhibit 99.1 AGREEMENT In accordance with Rule 13d-1(k) under the Securities Exchange Act of 1934, as amended, the persons named below agree to the joint filing on behalf of each of them of a statement on Schedule 13G (including amendments thereto) with respect to the Ordinary Shares (represented by ADS, each of which represents one Ordinary Share) of Autolus Th

November 14, 2024 SC 13G/A

AUTL / Autolus Therapeutics plc - Depositary Receipt (Common Stock) / Syncona Portfolio Ltd - SC 13G/A Passive Investment

SC 13G/A 1 d901415dsc13ga.htm SC 13G/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 7)* Autolus Therapeutics plc (Name of Issuer) American Depositary Shares and Ordinary Shares, nominal value $0.000042 per share (Title of Class of Securities) 05280R 100** (CUSIP Number) December 31, 2023 (Date of Event

November 14, 2024 S-8

As filed with the U.S. Securities and Exchange Commission on November 14, 2024

As filed with the U.S. Securities and Exchange Commission on November 14, 2024 Registration No. 333-    UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM S-8 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 Autolus Therapeutics plc (Exact name of registrant as specified in its charter) England and Wales Not applicable (State or other jurisdiction of Incorporation

November 14, 2024 SC 13G/A

AUTL / Autolus Therapeutics plc - Depositary Receipt (Common Stock) / Paradigm Biocapital Advisors LP - SC 13G/A Passive Investment

SC 13G/A 1 tm2427604d3sc13ga.htm SC 13G/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 2)* Autolus Therapeutics plc (Name of Issuer) Ordinary Shares, nominal value $0.000042 per share** (Title of Class of Securities) 05280R100*** (CUSIP Number) September 30, 2024 (Date of Event Which Requires Filing of

November 14, 2024 SC 13G/A

AUTL / Autolus Therapeutics plc - Depositary Receipt (Common Stock) / Deep Track Capital, LP Passive Investment

SC 13G/A 1 deeptrack-autl093024a3.htm UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 13G/A Under the Securities Exchange Act of 1934 (Amendment No. 3)* Autolus Therapeutics PLC (Name of Issuer) American Depositary Shares, each representing one ordinary share, nominal value $0.000042 per share (Title of Class of Securities) 05280R100 (CUSIP Number) September 30, 2024

November 14, 2024 EX-FILING FEES

Filing Fee Table.

Exhibit 107 Calculation of Filing Fee Table Form S-8 (Form Type) Autolus Therapeutics plc (Exact Name of Registrant as Specified in its Charter) Table 1: Newly Registered Securities Security Type Security Class Title(1) Fee Calculation Rule Amount Registered(2) Proposed Maximum Offering Price Per Unit Maximum Aggregate Offering Price Fee Rate Amount of Registration Fee Equity Ordinary shares  Other 10,644,770(3) $3.

November 12, 2024 EX-99.1

Autolus Therapeutics Reports Third Quarter 2024 Financial Results and Business Updates November 12, 2024 at 7:00 AM EST AUCATZYL® (obecabtagene autoleucel) approved by US FDA on November 8, ahead of target PDUFA date of November 16; US commercial lau

autlex-991pr121124 Autolus Therapeutics Reports Third Quarter 2024 Financial Results and Business Updates November 12, 2024 at 7:00 AM EST AUCATZYL® (obecabtagene autoleucel) approved by US FDA on November 8, ahead of target PDUFA date of November 16; US commercial launch initiated BLA approval triggers $30m milestone payment to Autolus from Blackstone Marketing authorizations for obe-cel under review with both the MHRA EMA Matthias Will M.

November 12, 2024 EX-10.4

Amended Management Incentive Compensation Plan

EX-10.4 Management Incentive Compensation Plan (October 2024) 1. Purpose of the Plan The Management Incentive Compensation Plan (the “Plan”) of Autolus Therapeutics plc and its group companies (collectively, “Autolus”) is designed to offer incentive compensation to officers and managers of Autolus (the “Associates”) by rewarding the achievement of corporate goals and specifically measured personal

November 12, 2024 EX-10.1

Capital Contribution Deed, dated September 10, 2024, between Forge Life Sciences Nominee I Limited and Forge Life Sciences Nominee 2 Limited, Autolus Limited and Autolus Therapeutics plc relating to The Nucleus Marshgate, Stevenage.

Email: [***] 4171312.18 Dated 2024 FORGE LIFE SCIENCES NOMINEE I LTD AND FORGE LIFE SCIENCES NOMINEE 2 LTD and AUTOLUS LIMITED and AUTOLUS THERAPEUTICS PLC Capital Contribution Deed relating to premises known as The Nucleus Marshgate, Stevenage SG1 1FR formerly known as part of The Marshgate Car Park, Stevenage EX-10.1 4171312.18 1 THIS DEED is dated the day of 2024 PARTIES (1) Forge Life Sciences

November 12, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 12, 2024 Autolus Therape

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 12, 2024 Autolus Therapeutics plc (Exact name of registrant as specified in its Charter) England and Wales 001-38547 Not applicable (State or other jurisdiction of incorporat

November 12, 2024 EX-10.3

Licence for Alterations, dated September 10, 2024, between Forge Life Sciences Nominee I Limited and Forge Life Sciences Nominee 2 Limited, Autolus Limited and Autolus Therapeutics plc relating to The Nucleus Marshgate, Stevenage.

Email: [***] 4171693.3 Dated 2024 FORGE LIFE SCIENCES NOMINEE 1 LTD AND FORGE LIFE SCIENCES NOMINEE 2 LTD and AUTOLUS LIMITED and AUTOLUS THERAPEUTICS PLC Licence for Alterations relating to The Nucleus Marshgate Stevenage SG1 1FR formerly known as part of The Marshgate Car Park, Stevenage EX-10.3 79025116.1 i TABLE OF CONTENTS No. Heading Page 1. INTERPRETATION AND GENERAL PROVISIONS 1 2. GRANT O

November 12, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 8, 2024 Autolus Therapeu

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 8, 2024 Autolus Therapeutics plc (Exact name of registrant as specified in its Charter) England and Wales 001-38547 Not applicable (State or other jurisdiction of incorporati

November 12, 2024 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

Table of contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2024 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Numbe

November 12, 2024 EX-99.2

Autolus.com FDA Approval Conference Call AUCATZYL® (obecabtagene autoleucel) For Investor communication only. Not for use in product promotion. Not for further distribution. EX-99.2 Disclaimer These slides contain forward-looking statements within th

autlex-992cp111124 Autolus.com FDA Approval Conference Call AUCATZYL® (obecabtagene autoleucel) For Investor communication only. Not for use in product promotion. Not for further distribution. EX-99.2 Disclaimer These slides contain forward-looking statements within the meaning of the “safe harbor” provisions of the Private Securities Litigation Reform Act of 1995. Forward-looking statements are s

November 12, 2024 EX-99.2

Q3 2024 Financial Results and Business Updates 12 November 2024 Autolus.com For Investor communication only. Not for use in product promotion. Not for further distribution. EX-99.2 Disclaimer These slides contain forward-looking statements within the

autlex-992cp121124 Q3 2024 Financial Results and Business Updates 12 November 2024 Autolus.

November 12, 2024 EX-10.2

Deed of Variation, dated September 10, 2024, between Forge Life Sciences Nominee I Limited and Forge Life Sciences Nominee 2 Limited, Autolus Limited and Autolus Therapeutics plc relating to The Nucleus Marshgate, Stevenage.

Email: [***] 4174912.2 Dated FORGE LIFE SCIENCES NOMINEE 1 LTD AND FORGE LIFE SCIENCES NOMINEE 2 LTD - and - AUTOLUS LIMITED and AUTOLUS THERAPEUTICS PLC Deed of Variation relating to premises known as The Nucleus Marshgate Stevenage SG1 1FR formerly known as part of The Marshgate Car Park, Stevenage EX-10.2 4174912.2 i TABLE OF CONTENTS No. Heading Page 1. DEFINITIONS AND INTERPRETATION 1 2. BACK

November 12, 2024 EX-99.1

1 Autolus Therapeutics Announces FDA Approval of AUCATZYL® (obecabtagene autoleucel – obe-cel) for adults with relapsed/refractory B-cell acute lymphoblastic leukemia (r/r B-ALL) - AUCATZYL is the first CAR T therapy approved by the FDA with no requi

autlex-991pr081124 1 Autolus Therapeutics Announces FDA Approval of AUCATZYL® (obecabtagene autoleucel – obe-cel) for adults with relapsed/refractory B-cell acute lymphoblastic leukemia (r/r B-ALL) - AUCATZYL is the first CAR T therapy approved by the FDA with no requirement for a REMS program (Risk Evaluation Mitigation Strategy) - Approval based on FELIX clinical trial of obe-cel in adult patien

November 8, 2024 SC 13G

AUTL / Autolus Therapeutics plc - Depositary Receipt (Common Stock) / WELLINGTON MANAGEMENT GROUP LLP - SEC SCHEDULE 13G Passive Investment

SC 13G 1 SEC13GFiling.htm SEC SCHEDULE 13G UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* Autolus Therapeutics plc (Name of Issuer) Common Stock (Title of Class of Securities) G06630100 (CUSIP Number) September 30, 2024 (Date of Event Which Requires Filing of this Statement) Check the appropriate box

November 8, 2024 EX-99

JOINT FILING AGREEMENT

JOINT FILING AGREEMENT The undersigned hereby agree that this Schedule 13G (the “Schedule 13G”) with respect to the common stock of Autolus Therapeutics plc is, and any additional amendment thereto signed by each of the undersigned shall be, filed on behalf of each undersigned pursuant to and in accordance with the provisions of 13d-1(k) under the Securities Exchange Act of 1934, as amended, and that all subsequent amendments to the Schedule 13G shall be filed on behalf of each of the undersigned without the necessity of filing additional joint filing agreements.

October 25, 2024 EX-99.3

Power of Attorney of AMALAR HOLDING s.r.o., dated as of August 5, 2024.

EX-99.3 3 ea021861902ex99-3autolus.htm POWER OF ATTORNEY OF AMALAR HOLDING S.R.O., DATED AS OF AUGUST 5, 2024 Exhibit 99.3 POWER OF ATTORNEY KNOW ALL BY THESE PRESENTS, that the undersigned does hereby constitute and appoint Lubomír Král and Radomír Johanna as the undersigned’s true and lawful attorneys-in-fact to, as applicable: (1) execute for and on behalf of the undersigned, in the undersigned

October 25, 2024 SC 13D/A

AUTL / Autolus Therapeutics plc - Depositary Receipt (Common Stock) / PPF Group N.V. - AMENDMENT NO. 10 TO SCHEDULE 13D Activist Investment

SC 13D/A 1 ea0218619-13da10ppfautolus.htm AMENDMENT NO. 10 TO SCHEDULE 13D UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D Under the Securities Exchange Act of 1934 (Amendment No. 10) AUTOLUS THERAPEUTICS PLC (Name of Issuer) American Depositary Shares, each representing one ordinary share, nominal value $0.000042 per share, and ordinary shares, nominal value $

October 25, 2024 EX-99.1

Joint Filing Agreement, dated as of October 25, 2024.

EX-99.1 2 ea021861902ex99-1autolus.htm JOINT FILING AGREEMENT, DATED AS OF OCTOBER 25, 2024 Exhibit 99.1 Joint Filing Agreement Pursuant to and in accordance with the Securities Exchange Act of 1934, as amended, and the rules and regulations thereunder (the “Exchange Act”), the undersigned hereby agree to the joint filing on behalf of each of them of any filing required by such party under Section

September 30, 2024 CORRESP

Autolus Therapeutics plc, The MediaWorks, 191 Wood Lane, London, W12 7FP, United Kingdom T: 020 3829 6230 www.autolus.com Registered in England no: 11185179

September 30, 2024 VIA EDGAR United States Securities and Exchange Commission Division of Corporation Finance Office of Life Sciences 100 F.

September 26, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 26, 2024 Autolus Therap

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 26, 2024 Autolus Therapeutics plc (Exact name of registrant as specified in its Charter) England and Wales 001-38547 Not applicable (State or other jurisdiction of incorpora

September 26, 2024 EX-99.1

Developing Next Generation Programmed T Cell Therapies September 2024 Autolus.com EX-99.1 Disclaimer These slides contain forward-looking statements within the meaning of the “safe harbor” provisions of the Private Securities Litigation Reform Act of

Developing Next Generation Programmed T Cell Therapies September 2024 Autolus.com EX-99.1 Disclaimer These slides contain forward-looking statements within the meaning of the “safe harbor” provisions of the Private Securities Litigation Reform Act of 1995. Forward-looking statements are statements that are not historical facts, and in some cases can be identified by terms such as “may,” “will,” “c

September 19, 2024 EX-99.1

1 Autolus Therapeutics announces appointment of Matthias Will, M.D. as Chief Development Officer LONDON, September 19, 2024 -- Autolus Therapeutics plc (Nasdaq: AUTL), a clinical-stage biopharmaceutical company developing next-generation programmed T

1 Autolus Therapeutics announces appointment of Matthias Will, M.D. as Chief Development Officer LONDON, September 19, 2024 - Autolus Therapeutics plc (Nasdaq: AUTL), a clinical-stage biopharmaceutical company developing next-generation programmed T cell therapies, announced the appointment of Matthias Will, M.D., as Chief Development Officer. Dr. Will is joining Autolus’ executive team and will l

September 19, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 13, 2024 Autolus Therap

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 13, 2024 Autolus Therapeutics plc (Exact name of registrant as specified in its Charter) England and Wales 001-38547 Not applicable (State or other jurisdiction of incorpora

September 13, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 10, 2024 Autolus Therap

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): September 10, 2024 Autolus Therapeutics plc (Exact name of registrant as specified in its Charter) England and Wales 001-38547 Not applicable (State or other jurisdiction of incorpora

August 8, 2024 EX-99.2

Q2 2024 Financial Results and Business Updates 8 August 2024 Autolus.com EX-99.2 Disclaimer These slides contain forward-looking statements within the meaning of the “safe harbor” provisions of the Private Securities Litigation Reform Act of 1995. Fo

Q2 2024 Financial Results and Business Updates 8 August 2024 Autolus.com EX-99.2 Disclaimer These slides contain forward-looking statements within the meaning of the “safe harbor” provisions of the Private Securities Litigation Reform Act of 1995. Forward-looking statements are statements that are not historical facts, and in some cases can be identified by terms such as “may,” “will,” “could,” “e

August 8, 2024 EX-99.1

Autolus Therapeutics Reports Second Quarter 2024 Financial Results and Business Updates August 8, 2024 at 7:00 AM EDT On track for potential US commercial launch of obe-cel; PDUFA date November 16, 2024 Longer follow up and subset analyses from pivot

Autolus Therapeutics Reports Second Quarter 2024 Financial Results and Business Updates August 8, 2024 at 7:00 AM EDT On track for potential US commercial launch of obe-cel; PDUFA date November 16, 2024 Longer follow up and subset analyses from pivotal FELIX Phase 2 data presented at ASCO and EHA; majority of responders showed durable responses; 40% of patients in ongoing remission without subsequent stem cell transplant (SCT) or other intervention A Market Authorization Application (MAA) for obe-cel in relapsed/refractory r/r adult B-cell Acute Lymphoblastic Leukemia (B-ALL) was submitted to the Medicine and Healthcare products Regulatory Authority (MHRA) in the UK at the end of July 2024.

August 8, 2024 8-K

Regulation FD Disclosure, Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): August 8, 2024 Autolus Therapeutics plc (Exact name of registrant as specified in its Charter) England and Wales 001-38547 Not applicable (State or other jurisdiction of incorporation

August 8, 2024 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

Table of contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2024 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number 001

June 28, 2024 8-K

Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 28, 2024 Autolus Therapeutics plc (Exact name of registrant as specified in its Charter) England and Wales 001-38547 Not applicable (State or other jurisdiction of incorporation

June 5, 2024 EX-99.2

1 THIS DOCUMENT IS IMPORTANT AND REQUIRES YOUR IMMEDIATE ATTENTION. If you are in any doubt as to the action to be taken, please seek your own financial advice from your stockbroker, solicitor, accountant or other appropriately authorised independent

1 THIS DOCUMENT IS IMPORTANT AND REQUIRES YOUR IMMEDIATE ATTENTION. If you are in any doubt as to the action to be taken, please seek your own financial advice from your stockbroker, solicitor, accountant or other appropriately authorised independent financial adviser. If you have recently sold or transferred all of your ordinary shares in Autolus Therapeutics plc, you should forward this document

June 5, 2024 EX-99.3

MR A SAMPLE < DESIGNATION> SAMPLE STREET SAMPLE TOWN SAMPLE CITY SAMPLE COUNTY AA11 1AA MR A SAMPLE < Designation> Additional Holder 1 Additional Holder 2 Additional Holder 3 Additional Holder 4 Form of Proxy - Annual General Meeting to be held on 28

MR A SAMPLE < DESIGNATION> SAMPLE STREET SAMPLE TOWN SAMPLE CITY SAMPLE COUNTY AA11 1AA MR A SAMPLE < Designation> Additional Holder 1 Additional Holder 2 Additional Holder 3 Additional Holder 4 Form of Proxy - Annual General Meeting to be held on 28 June 2024 Kindly Note: This form is issued only to the addressee(s) and is specific to the unique designated account printed hereon.

June 5, 2024 8-K

Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): June 5, 2024 Autolus Therapeutics plc (Exact name of registrant as specified in its Charter) England and Wales 001-38547 Not applicable (State or other jurisdiction of incorporation o

June 5, 2024 EX-99.1

Registered Number 11185179 (England & Wales) Annual Report and financial statements for the year ended 31 December 2023 for Autolus Therapeutics plc Introduction and Contents Autolus Therapeutics plc (the “Company”, “Group” or “Parent Company”) is a

Registered Number 11185179 (England & Wales) Annual Report and financial statements for the year ended 31 December 2023 for Autolus Therapeutics plc Introduction and Contents Autolus Therapeutics plc (the “Company”, “Group” or “Parent Company”) is a public limited company incorporated under the laws of England and Wales and is listed on the Nasdaq Global Select Market (“NASDAQ”).

June 3, 2024 EX-99.1

Autolus Therapeutics presents longer-term follow-up and additional data analysis of Pivotal Phase 2 FELIX study of obe-cel for adult r/r B-ALL in an oral presentation at ASCO May 31, 2024 at 8:00 AM EDT The majority of patients that responded to obe-

Autolus Therapeutics presents longer-term follow-up and additional data analysis of Pivotal Phase 2 FELIX study of obe-cel for adult r/r B-ALL in an oral presentation at ASCO May 31, 2024 at 8:00 AM EDT The majority of patients that responded to obe-cel showed durable responses with the potential for a long-term plateau of survival outcomes 40% patients are in ongoing remission without subsequent

June 3, 2024 8-K

Regulation FD Disclosure, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 31, 2024 Autolus Therapeutics plc (Exact name of registrant as specified in its Charter) England and Wales 001-38547 Not applicable (State or other jurisdiction of incorporation o

June 3, 2024 EX-99.2

American Society of Clinical Oncology Analyst Call 1 June 2024 Autolus.com Disclaimer These slides contain forward-looking statements within the meaning of the “safe harbor” provisions of the Private Securities Litigation Reform Act of 1995. Forward-

American Society of Clinical Oncology Analyst Call 1 June 2024 Autolus.com Disclaimer These slides contain forward-looking statements within the meaning of the “safe harbor” provisions of the Private Securities Litigation Reform Act of 1995. Forward-looking statements are statements that are not historical facts, and in some cases can be identified by terms such as “may,” “will,” “could,” “expects

May 21, 2024 SC 13D/A

AUTL / Autolus Therapeutics plc - Depositary Receipt (Common Stock) / Blackstone Group Inc - SC 13D/A Activist Investment

SC 13D/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D Under the Securities Exchange Act of 1934 (Amendment No. 2)* Autolus Therapeutics plc (Name of Issuer) American Depositary Shares, each representing one ordinary share, nominal value $0.000042 per share (Title of Class of Securities) 05280R100 ** (CUSIP Number) John G. Finley Blackstone Inc. 345 Park Aven

May 17, 2024 EX-99.2

Q1 2024 Financial Results and Business Updates 17 May 2024 Autolus.com Disclaimer These slides contain forward-looking statements within the meaning of the “safe harbor” provisions of the Private Securities Litigation Reform Act of 1995. Forward-look

Q1 2024 Financial Results and Business Updates 17 May 2024 Autolus.com Disclaimer These slides contain forward-looking statements within the meaning of the “safe harbor” provisions of the Private Securities Litigation Reform Act of 1995. Forward-looking statements are statements that are not historical facts, and in some cases can be identified by terms such as “may,” “will,” “could,” “expects,” “

May 17, 2024 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

Table of contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2024 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Number 00

May 17, 2024 EX-99.1

1 Autolus Therapeutics Reports First Quarter 2024 Financial Results and Business Updates • Longer follow up and subset analyses from the pivotal FELIX Phase 2 data to be presented in oral presentations at ASCO and EHA • Two patients enrolled in Phase

1 Autolus Therapeutics Reports First Quarter 2024 Financial Results and Business Updates • Longer follow up and subset analyses from the pivotal FELIX Phase 2 data to be presented in oral presentations at ASCO and EHA • Two patients enrolled in Phase 1 Systemic Lupus Erythematosus (SLE) trial; study on track for initial data end of 2024 • Market Authorization Application (MAA) for obe-cel in r/r a

May 17, 2024 8-K

Regulation FD Disclosure, Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 17, 2024 Autolus Therapeutics plc (Exact name of registrant as specified in its Charter) England and Wales 001-38547 Not applicable (State or other jurisdiction of incorporation o

May 13, 2024 EX-99.1

Autolus Therapeutics Announces Delay to its First Quarter 2024 Earnings Release and Conference Call

Exhibit 99.1 Autolus Therapeutics Announces Delay to its First Quarter 2024 Earnings Release and Conference Call LONDON, May 13, 2024 — Autolus Therapeutics plc (Nasdaq: AUTL), a clinical-stage biopharmaceutical company developing next-generation programmed T cell therapies, today announced that it intends to file a Form 12b-25, Notification of Late Filing, with the U.S. Securities and Exchange Co

May 13, 2024 NT 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 12b-25 NOTIFICATION OF LATE FILING Commission File Number: 001-38547

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 12b-25 NOTIFICATION OF LATE FILING Commission File Number: 001-38547 (Check one): ☐ Form 10-K ☐ Form 20-F ☐ Form 11-K ☒ Form 10-Q ☐ Form 10-D ☐ Form N-CEN ☐ Form N-CSR For Period Ended: March 31, 2024 ☐ Transition Report on Form 10-K ☐ Transition Report on Form 20-F ☐ Transition Report on Form 11-K ☐ Transition Report on

May 13, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 13, 2024 Autolus Therapeutics

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): May 13, 2024 Autolus Therapeutics plc (Exact name of registrant as specified in its Charter) England and Wales 001-38547 Not applicable (State or other jurisdiction of incorporation o

April 1, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 26, 2024 Autolus Therapeuti

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 26, 2024 Autolus Therapeutics plc (Exact name of registrant as specified in its Charter) England and Wales 001-38547 Not applicable (State or other jurisdiction of incorporation

April 1, 2024 EX-99.1

1 Autolus Therapeutics Announces Changes to its Board of Directors LONDON, April 1, 2024 – Autolus Therapeutics plc (Nasdaq: AUTL), a clinical-stage biopharmaceutical company developing next-generation programmed T cell therapies, today announces the

1 Autolus Therapeutics Announces Changes to its Board of Directors LONDON, April 1, 2024 – Autolus Therapeutics plc (Nasdaq: AUTL), a clinical-stage biopharmaceutical company developing next-generation programmed T cell therapies, today announces the appointment of Mike Bonney as Chairman of the Board, and Ravi Rao M.

March 28, 2024 S-3ASR

As filed with the Securities and Exchange Commission on March 28, 2024

Table of Contents As filed with the Securities and Exchange Commission on March 28, 2024 Registration No.

March 28, 2024 EX-FILING FEES

Filing Fee Table

Exhibit 107 Calculation of Filing Fee Table Form S-3 (Form Type) Autolus Therapeutics plc (Exact Name of Registrant as Specified in its Charter) Table 1: Newly Registered Securities Security Type Security Class Title Fee Calculation Rule Amount Registered(1)(2) Proposed Maximum Offering Price Per Unit Maximum Aggregate Offering Price Fee Rate Amount of Registration Fee(6) Equity American Depositary Shares (ADSs) 457(c) 33,333,333 $6.

March 25, 2024 SC 13D/A

AUTL / Autolus Therapeutics plc - Depositary Receipt (Common Stock) / Kellnerova Renata - AMENDMENT NO. 9 TO SCHEDULE 13D Activist Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D Under the Securities Exchange Act of 1934 (Amendment No. 9) AUTOLUS THERAPEUTICS PLC (Name of Issuer) American Depositary Shares, each representing one ordinary share, nominal value $0.000042 per share, and ordinary shares, nominal value $0.000042 per share (Title of Class of Securities) 05280R100** (CUSIP Number)

March 21, 2024 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K x ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2023 o TRANSITION REPORT PURSUANT TO SECTI

Table of contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K x ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2023 OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 for the transition period from to Commission file number: 001-38547 Autolus

March 21, 2024 EX-10.12

License and Option Agreement between the registrant and BioNTech SE, dated February 6, 2024.

299246678 v1 [***] Certain information in this document has been omitted from this exhibit because it is both (i) not material and (ii) is the type that the Registrant treats as private or confidential.

March 21, 2024 EX-21.1

Subsidiaries of the registrant.

Exhibit 21.1 Autolus Therapeutics plc List of Subsidiaries Subsidiary Jurisdiction Autolus Holdings (UK) Limited England and Wales Autolus Limited England and Wales Autolus Inc. Delaware Autolus GmbH Germany Autolus Switzerland AG Switzerland

March 21, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 21, 2024 Autolus Therapeuti

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 21, 2024 Autolus Therapeutics plc (Exact name of registrant as specified in its Charter) England and Wales 001-38547 Not applicable (State or other jurisdiction of incorporation

March 21, 2024 EX-97.1

erroneously awarded compensation, as required by applicable listing

290949680 v3 AUTOLUS THERAPEUTICS PLC INCENTIVE COMPENSATION RECOUPMENT POLICY 1. INTRODUCTION The Compensation Committee (the “Compensation Committee”) of the Board of Directors (the “Board”) of Autolus Therapeutics plc, a public limited company incorporated under the laws of England and Wales (the “Company”), has determined that it is in the best interests of the Company and its shareholders to

March 15, 2024 8-K/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K/A CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 14, 2024 Autolus Therapeu

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K/A CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 14, 2024 Autolus Therapeutics plc (Exact name of registrant as specified in its Charter) England and Wales 001-38547 Not applicable (State or other jurisdiction of incorporati

March 15, 2024 EX-99.1

Event ID: 138235356103 Event Name: Q4 2023 Autolus Therapeutics PLC Earnings Call Event Date: 2024-03-14T12:30:00 UTC P: Operator;; C: Olivia Manser;Autolus Therapeutics PLC;Investor Relations C: Christian Itin;Autolus Therapeutics PLC;Chief Executiv

Event ID: 138235356103 Event Name: Q4 2023 Autolus Therapeutics PLC Earnings Call Event Date: 2024-03-14T12:30:00 UTC P: Operator;; C: Olivia Manser;Autolus Therapeutics PLC;Investor Relations C: Christian Itin;Autolus Therapeutics PLC;Chief Executive Officer, Executive Director C: Rob Dolski;Autolus Therapeutics PLC;Chief Financial Officer P: James Shin;Deutsche Bank;Analyst P: Unidentified Participant;; P: Gil Blum;Needham & Company Inc.

March 14, 2024 8-K

Regulation FD Disclosure, Financial Statements and Exhibits, Results of Operations and Financial Condition, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): March 14, 2024 Autolus Therapeutics plc (Exact name of registrant as specified in its Charter) England and Wales 001-38547 Not applicable (State or other jurisdiction of incorporation

March 14, 2024 EX-99.1

Autolus Therapeutics Reports Full Year 2023 Financial Results and Business Updates March 14, 2024 at 7:00 AM EDT Announced strategic collaboration and equity investment from BioNTech for aggregate proceeds of $250 million upfront, plus underwritten o

Autolus Therapeutics Reports Full Year 2023 Financial Results and Business Updates March 14, 2024 at 7:00 AM EDT Announced strategic collaboration and equity investment from BioNTech for aggregate proceeds of $250 million upfront, plus underwritten offering of ADSs for $350 million, for gross proceeds of $600 million received in February 2024 Submitted a Biologics License Application (BLA) for obe

March 14, 2024 EX-99.2

Full Year 2023 Financial Results and Business Updates March 14, 2024 EX-99.2 Disclaimer 2Developing Next Generation Programmed T Cell Therapies These slides contain forward-looking statements within the meaning of the "safe harbor" provisions of the

Full Year 2023 Financial Results and Business Updates March 14, 2024 EX-99.2 Disclaimer 2Developing Next Generation Programmed T Cell Therapies These slides contain forward-looking statements within the meaning of the "safe harbor" provisions of the Private Securities Litigation Reform Act of 1995. Forward-looking statements are statements that are not historical facts, and in some cases can be id

February 21, 2024 SC 13D

AUTL / Autolus Therapeutics plc - Depositary Receipt (Common Stock) / BioNTech SE - SC 13D Activist Investment

SC 13D 1 d782522dsc13d.htm SC 13D UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D Under the Securities Exchange Act of 1934 (Amendment No. )* Autolus Therapeutics plc (Name of Issuer) Ordinary shares, nominal value $0.000042 per share (including ordinary shares represented by American Depositary Shares)** (Title of Class of Securities) 05280R100*** (CUSIP Numbe

February 14, 2024 SC 13G/A

AUTL / Autolus Therapeutics plc - Depositary Receipt (Common Stock) / Paradigm Biocapital Advisors LP - SC 13G/A Passive Investment

SC 13G/A 1 tm245955d3sc13ga.htm SC 13G/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 1)* Autolus Therapeutics plc (Name of Issuer) Ordinary Shares, nominal value $0.000042 per share** (Title of Class of Securities) 05280R100*** (CUSIP Number) December 31, 2023 (Date of Event Which Requires Filing of t

February 14, 2024 SC 13G/A

AUTL / Autolus Therapeutics plc - Depositary Receipt (Common Stock) / ARMISTICE CAPITAL, LLC Passive Investment

SC 13G/A 1 armistice-autl123123a1.htm UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 13G/A Under the Securities Exchange Act of 1934 (Amendment No. 1)* Autolus Therapeutics, plc (Name of Issuer) American Depository Shares, each representing one ordinary share, nominal value $0.000042 per share (Title of Class of Securities) 05280R100 (CUSIP Number) December 31, 2023

February 14, 2024 SC 13G/A

AUTL / Autolus Therapeutics plc - Depositary Receipt (Common Stock) / Deep Track Capital, LP Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 13G/A Under the Securities Exchange Act of 1934 (Amendment No.

February 13, 2024 EX-99.1

AGREEMENT

EX-99.1 2 d783202dex991.htm EX-99.1 Exhibit 99.1 AGREEMENT In accordance with Rule 13d-1(k) under the Securities Exchange Act of 1934, as amended, the persons named below agree to the joint filing on behalf of each of them of a statement on Schedule 13G (including amendments thereto) with respect to the Ordinary Shares (represented by ADS, each of which represents one Ordinary Share) of Autolus Th

February 13, 2024 EX-99.1

Disclaimer Developing Next Generation Programmed T Cell Therapies These slides contain forward-looking statements within the meaning of the "safe harbor" provisions of the Private Securities Litigation Reform Act of 1995. Forward-looking statements a

Developing Next Generation Programmed T Cell Therapies February 2024 Exhibit 99.1 Disclaimer Developing Next Generation Programmed T Cell Therapies These slides contain forward-looking statements within the meaning of the "safe harbor" provisions of the Private Securities Litigation Reform Act of 1995. Forward-looking statements are statements that are not historical facts, and in some cases can b

February 13, 2024 8-K

Regulation FD Disclosure

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 13, 2024 Autolus Therapeutics plc (Exact name of registrant as specified in its Charter) England and Wales 001-38547 Not applicable (State or other jurisdiction of incorporat

February 13, 2024 SC 13G/A

AUTL / Autolus Therapeutics plc - Depositary Receipt (Common Stock) / Syncona Portfolio Ltd - SC 13G/A Passive Investment

SC 13G/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 6)* Autolus Therapeutics plc (Name of Issuer) American Depositary Shares and Ordinary Shares, nominal value $0.000042 per share (Title of Class of Securities) 05280R 100** (CUSIP Number) December 31, 2023 (Date of Event which Requires Filing of this

February 9, 2024 EX-FILING FEES

Calculation of Filing Fee Tables (Form Type) Autolus Therapeutics plc (Exact Name of Registrant as Specified in its Charter) Table 1: Newly Registered and Carry Forward Securities  Security  Type Security  Class Title  Fee  Calculation  or Carry Forw

Exhibit 107 Calculation of Filing Fee Tables 424(b)(5) (Form Type) Autolus Therapeutics plc (Exact Name of Registrant as Specified in its Charter) Table 1: Newly Registered and Carry Forward Securities  Security  Type Security  Class Title  Fee  Calculation  or Carry Forward Rule Amount  Registered  Proposed  Maximum  Offering Price Per Unit Maximum Aggregate Offering Price(1) Fee Rate Amount of Registration Fee Carry Forward Form Type Carry Forward File Number Carry   forward   Initial Effective Date Filing Fee Previously Paid in Connection with Unsold Securities to be Carried Forward Newly Registered Securities Fees to be Paid Equity Ordinary shares, nominal value $0.

February 9, 2024 424B5

58,333,336 American Depositary Shares Representing Ordinary Shares

Table of Contents Filed Pursuant to Rule 424(b)(5) Registration File No. 333-276942 PROSPECTUS SUPPLEMENT (To Prospectus Dated February 8, 2024) 58,333,336 American Depositary Shares Representing Ordinary Shares We are offering 58,333,336 of our American Depositary Shares, or ADSs. Each ADS represents one ordinary share with a nominal value of $0.000042 per share. The ADSs may be evidenced by Amer

February 8, 2024 8-K

Regulation FD Disclosure, Entry into a Material Definitive Agreement

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 6, 2024 Autolus Therapeutics plc (Exact name of registrant as specified in its Charter) England and Wales 001-38547 Not applicable (State or other jurisdiction of incorporati

February 8, 2024 EX-4.7

Form of Indenture.

Exhibit 4.7 Autolus Therapeutics plc, Issuer AND [TRUSTEE], Trustee FORM OF INDENTURE Dated as of [•], 20 Debt Securities TABLE OF CONTENTS PAGE ARTICLE 1 DEFINITIONS 1 Section 1.01 Definitions of Terms 1 ARTICLE 2 ISSUE, DESCRIPTION, TERMS, EXECUTION, REGISTRATION AND EXCHANGE OF SECURITIES 4 Section 2.01 Designation and Terms of Securities 4 Section 2.02 Form of Securities and Trustee’s Certific

February 8, 2024 EX-1.1

Underwriting Agreement, dated as of February 8, 2024, by and among the Company, Jefferies LLC and Truist Securities, Inc., as representatives of the several underwriters named therein.

Exhibit 1.1 Autolus Therapeutics plc American Depositary Shares Representing Ordinary Shares Underwriting Agreement February 8, 2024 Jefferies LLC Truist Securities, Inc. as representatives (the “Representatives”) of the several Underwriters named in Schedule I hereto Jefferies LLC 520 Madison Avenue New York, New York 10022 Truist Securities, Inc. 3333 Peachtree Road NE 11th Floor Atlanta, GA 303

February 8, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 8, 2024 Autolus Therapeu

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): February 8, 2024 Autolus Therapeutics plc (Exact name of registrant as specified in its Charter) England and Wales 001-38547 Not applicable (State or other jurisdiction of incorporati

February 8, 2024 EX-4.10

Form of Debt Securities Warrant Agreement and Warrant Certificate.

Exhibit 4.10 AUTOLUS THERAPEUTICS PLC AND , AS WARRANT AGENT FORM OF DEBT SECURITIES WARRANT AGREEMENT DATED AS OF AUTOLUS THERAPEUTICS PLC FORM OF DEBT SECURITIES WARRANT AGREEMENT THIS DEBT SECURITIES WARRANT AGREEMENT (this “Agreement”), dated as of [•], between AUTOLUS THERAPEUTICS PLC, a public limited company incorporated under the laws of England and Wales under company number 11185179 and

February 8, 2024 EX-10.3

Letter Agreement between the registrant and BioNTech SE, dated February 6, 2024.

Exhibit 10.3 Execution Version AUTOLUS THERAPEUTICS PLC The MediaWorks 191 Wood Lane London, W12 7FP, United Kingdom 6 February 2024 BioNTech SE An der Goldgrube 12 55131 Mainz Germany Re: Director Nomination and Shareholder Restrictions This letter agreement (this “Letter Agreement”) confirms the agreement between Autolus Therapeutics plc (registered number 11185179), a public limited company inc

February 8, 2024 EX-10.1

Securities Purchase Agreement between the registrant and BioNTech SE, dated February 6, 2024.

Exhibit 10.1 Execution Version SECURITIES PURCHASE AGREEMENT This SECURITIES PURCHASE AGREEMENT (this “Agreement”) is made and entered into as of February 6, 2024 by and among AUTOLUS THERAPEUTICS PLC (registered number 11185179), a public limited company incorporated in England and Wales whose registered office is at The MediaWorks, 191 Wood Lane, London W12 7FP, United Kingdom (the “Company”), a

February 8, 2024 EX-10.2

Registration Rights Agreement between the registrant and BioNTech SE, dated February 6, 2024.

Exhibit 10.2 Execution Version AUTOLUS THERAPEUTICS PLC REGISTRATION RIGHTS AGREEMENT This REGISTRATION RIGHTS AGREEMENT (this “Agreement”) is made and entered into as of February 6, 2024 by and between Autolus Therapeutics plc, a public limited company incorporated under the laws of England and Wales (the “Company”), and BioNTech SE, a Societas Europaea organized and existing under the laws of Ge

February 8, 2024 EX-4.9

Form of Ordinary Share Warrant Agreement and Warrant Certificate.

Exhibit 4.9 AUTOLUS THERAPEUTICS PLC AND , AS WARRANT AGENT FORM OF ORDINARY SHARES WARRANT AGREEMENT DATED AS OF AUTOLUS THERAPEUTICS PLC FORM OF ORDINARY SHARES WARRANT AGREEMENT THIS ORDINARY SHARES WARRANT AGREEMENT (this “Agreement”), dated as of [•], between AUTOLUS THERAPEUTICS PLC, a public limited company incorporated under the laws of England and Wales under company number 11185179 and h

February 8, 2024 S-3ASR

As filed with the Securities and Exchange Commission on February 8, 2024

S-3ASR Table of Contents As filed with the Securities and Exchange Commission on February 8, 2024 Registration No.

February 8, 2024 EX-99.1

BioNTech and Autolus Announce Strategic CAR-T Cell Therapy Collaboration to Advance Pipeline and Expand Late-Stage Programs

Exhibit 99.1 BioNTech and Autolus Announce Strategic CAR-T Cell Therapy Collaboration to Advance Pipeline and Expand Late-Stage Programs • Strategic alliance leverages manufacturing and commercial infrastructure as well as technology with the aim to advance both companies’ autologous CAR-T programs towards market, pending market authorization • BioNTech secures the right to utilize Autolus’ manufa

February 8, 2024 EX-99.1

Autolus Announces Pricing of Underwritten Offering

Exhibit 99.1 Autolus Announces Pricing of Underwritten Offering LONDON – 8 February 2024 – Autolus Therapeutics plc (Nasdaq: AUTL), a clinical-stage biopharmaceutical company developing next-generation programmed T cell therapies, today announced the pricing of an underwritten offering in the United States of 58,333,336 American Depositary Shares (“ADSs”) representing 58,333,336 ordinary shares at

February 8, 2024 EX-FILING FEES

Filing Fee Table

Exhibit 107 Calculation of Filing Fee Tables Form S-3 (Form Type) Autolus Therapeutics plc (Exact Name of Registrant as Specified in its Charter) Table 1: Newly Registered and Carry Forward Securities Security Type Security Class Title(1) Fee Calculation or Carry Forward Rule Amount Registered Proposed Maximum Offering Price per Unit Maximum Aggregate Offering Price Fee Rate Amount of Registration Fee Carry Forward Form Type Carry Forward File Number Carry Forward Initial Effective Date Filing Fee Previously Paid in Connection with Unsold Securities to be Carried Forward Newly Registered Securities Fees to Be Paid Equity Ordinary shares, nominal value $0.

January 31, 2024 SC 13G/A

AUTL / Autolus Therapeutics plc - Depositary Receipt (Common Stock) / Tetragon Financial Management LP - AUTOLUS THERAPEUTICS PLC Passive Investment

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G/A Under the Securities Exchange Act of 1934 (Amendment No. 1)* Autolus Therapeutics plc (Name of Issuer) Ordinary shares, nominal value $0.000042 per share (Title of Class of Securities) 05280R100** (CUSIP Number) December 31, 2023 (Date of Event Which Requires Filing of This Statement) Check the appropriate box to designate th

January 26, 2024 8-K

Regulation FD Disclosure, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 22, 2024 Autolus Therapeutics plc (Exact name of registrant as specified in its Charter) England and Wales 001-38547 Not applicable (State or other jurisdiction of incorporati

January 26, 2024 EX-99.1

Autolus Therapeutics announces acceptance of Biologics License Application for obecabtagene autoleucel (obe-cel) as a potential treatment for relapsed/refractory Adult B-cell Acute Lymphoblastic Leukemia (ALL) January 22, 2024 at 7:00 AM EST PDUFA Go

Autolus Therapeutics announces acceptance of Biologics License Application for obecabtagene autoleucel (obe-cel) as a potential treatment for relapsed/refractory Adult B-cell Acute Lymphoblastic Leukemia (ALL) January 22, 2024 at 7:00 AM EST PDUFA Goal date is November 16, 2024 Company on track to submit a marketing authorization application to the European Medicines Agency (EMA) in the first half of 2024 LONDON, Jan.

January 10, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 9, 2024 Autolus Therapeut

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): January 9, 2024 Autolus Therapeutics plc (Exact name of registrant as specified in its Charter) England and Wales 001-38547 Not applicable (State or other jurisdiction of incorporatio

January 10, 2024 EX-99.1

Autolus Therapeu�cs announces the appointment of Robert W. Azelby to its Board of Directors LONDON, January 10, 2024 -- Autolus Therapeu�cs plc (Nasdaq: AUTL), a clinical-stage biopharmaceu�cal company developing next-genera�on programmed T cell ther

Autolus Therapeu�cs announces the appointment of Robert W. Azelby to its Board of Directors LONDON, January 10, 2024 - Autolus Therapeu�cs plc (Nasdaq: AUTL), a clinical-stage biopharmaceu�cal company developing next-genera�on programmed T cell therapies, today announced the appointment of Robert W. Azelby to the Board of Directors. Mr. Azelby brings more than 30 years of biopharmaceu�cal leadersh

December 22, 2023 EX-99.1

Autolus Therapeu�cs Announces Changes to its Board of Directors - Appointment of Elisabeth (“Lis”) Leiderman, M.D. - Resigna�on of Kapil Dhingra, M.D. LONDON, December 22, 2023 -- Autolus Therapeu�cs plc (Nasdaq: AUTL), a clinical-stage biopharmaceu�

pressreleasedateddecembe Autolus Therapeu�cs Announces Changes to its Board of Directors - Appointment of Elisabeth (“Lis”) Leiderman, M.

December 22, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 19, 2023 Autolus Therape

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 19, 2023 Autolus Therapeutics plc (Exact name of registrant as specified in its Charter) England and Wales 001-38547 Not applicable (State or other jurisdiction of incorporat

December 11, 2023 EX-99.1

ACTIVE/112974591.2 Exhibit 99.1 Autolus Therapeutics Presents Clinical Data Updates at the American Society of Hematology (ASH) Annual Meeting 2023 - Pooled analysis of the FELIX Phase Ib/II study demonstrated prolonged event free survival and low ov

ACTIVE/112974591.2 Exhibit 99.1 Autolus Therapeutics Presents Clinical Data Updates at the American Society of Hematology (ASH) Annual Meeting 2023 - Pooled analysis of the FELIX Phase Ib/II study demonstrated prolonged event free survival and low overall immunotoxicity across all cohorts in r/r B-ALL, and particularly in patients with low leukemic burden at lymphodepletion - Longer-term data from

December 11, 2023 EX-99.2

Developing Next Generation Programmed T Cell Therapies ASH Analyst Meeting and Webcast December 2023 Disclaimer 2Developing Next Generation Programmed T Cell Therapies These slides contain forward-looking statements within the meaning of the "safe ha

ashcorporatepresentation Developing Next Generation Programmed T Cell Therapies ASH Analyst Meeting and Webcast December 2023 Disclaimer 2Developing Next Generation Programmed T Cell Therapies These slides contain forward-looking statements within the meaning of the "safe harbor" provisions of the Private Securities Litigation Reform Act of 1995.

December 11, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 9, 2023 Autolus Therapeu

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): December 9, 2023 Autolus Therapeutics plc (Exact name of registrant as specified in its Charter) England and Wales 001-38547 Not applicable (State or other jurisdiction of incorporati

November 27, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 27, 2023 Autolus Therape

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 27, 2023 Autolus Therapeutics plc (Exact name of registrant as specified in its Charter) England and Wales 001-38547 Not applicable (State or other jurisdiction of incorporat

November 27, 2023 EX-99.1

1 Autolus Therapeutics Submits Biologics License Application to U.S. Food and Drug Administration for obecabtagene autoleucel (obe-cel) for Patients with Relapsed/refractory (r/r) Adult B-Cell Acute Lymphoblastic Leukemia (ALL) • BLA submission inclu

1 Autolus Therapeutics Submits Biologics License Application to U.S. Food and Drug Administration for obecabtagene autoleucel (obe-cel) for Patients with Relapsed/refractory (r/r) Adult B-Cell Acute Lymphoblastic Leukemia (ALL) • BLA submission includes results from pivotal Phase 2 FELIX study evaluating obe-cel in relapsed/refractory (r/r) adult B-cell Acute Lymphoblastic Leukemia (ALL) • Company

November 9, 2023 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q

Table of contents UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q (Mark One) ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2023 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the transition period from to Commission File Numbe

November 9, 2023 EX-10.2

Amendment 2 to Supply Agreement, dated as of September 27, 2023, by and between Autolus Limited and Miltenyi Biotec B.V. & Co. KG.

Confidential 1 of 16 AMENDMENT NO. 2 TO SUPPLY AGREEMENT This Amendment No. 2 to Supply Agreement (the “Amendment”) between the Parties is made and effective as of the date of the last signature (the “Amendment Effective Date”), by and between: Autolus Limited, a corporation having its principal place of business at MediaWorks, 191 Wood Lane, White City, London, W12 7FP, United Kingdom (“Autolus”)

November 9, 2023 EX-10.1

Lease Agreement, dated September 19, 2023, between Forge Life Sciences Nominee I Limited and Forge Life Sciences Nominee 2 Limited, Autolus Limited and Autolus Therapeutics plc relating to The Nucleus Marshgate, Stevenage.

19 September Dated 2023 FORGE LIFE SCIENCES NOMINEE 1 LIMITED AND FORGE LIFE SCIENCES NOMINEE 2 LIMITED and AUTOLUS LIMITED and AUTOLUS THERAPEUTICS PLC LEASE OF THE NUCLEUS MARSHGATE STEVENAGE SG1 1FR FORMERLY KNOWN AS PART OF THE MARSHGATE CAR PARK, STEVENAGE 76907807.

November 9, 2023 8-K

Regulation FD Disclosure

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): November 9, 2023 Autolus Therapeutics plc (Exact name of registrant as specified in its Charter) England and Wales 001-38547 Not applicable (State or other jurisdiction of incorporati

November 3, 2023 EX-FILING FEES

Filing Fee Table.

Exhibit 107 Calculation of Filing Fee Table Form S-8 (Form Type) Autolus Therapeutics plc (Exact Name of Registrant as Specified in its Charter) Table 1: Newly Registered Securities Security Type Security Class Title Fee Calculation Rule Amount Registered(1) Proposed Maximum Offering Price Per Unit Maximum Aggregate Offering Price Fee Rate Amount of Registration Fee Equity Ordinary shares, nominal value $0.

November 3, 2023 S-8

As filed with the U.S. Securities and Exchange Commission on November 3, 2023

S-8 As filed with the U.S. Securities and Exchange Commission on November 3, 2023 Registration No. 333- UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM S-8 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 Autolus Therapeutics plc (Exact name of registrant as specified in its charter) England and Wales Not applicable (State or other jurisdiction of Incorporation

November 2, 2023 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of November 2023 Commission File Number: 001-3

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of November 2023 Commission File Number: 001-38547 Autolus Therapeutics plc (Translation of registrant’s name into English) The MediaWorks 191 Wood Lane London W12 7FP United Kingdom (Address of p

November 2, 2023 EX-99.3

Autolus Therapeutics Reports Third Quarter 2023 Financial Results and Business Updates November 2, 2023 at 7:12 AM EDT Obe-cel, a potentially transformational treatment for relapsed/refractory (r/r) adult B-cell Acute Lymphoblastic Leukemia (ALL), on

Autolus Therapeutics Reports Third Quarter 2023 Financial Results and Business Updates November 2, 2023 at 7:12 AM EDT Obe-cel, a potentially transformational treatment for relapsed/refractory (r/r) adult B-cell Acute Lymphoblastic Leukemia (ALL), on track for a Biologics License Application (BLA) submission to the US Food & Drug Administration (FDA) by end of 2023 Updated clinical data at the Ame

November 2, 2023 EX-99.2

MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS

Exhibit 99.2 MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS The following discussion and analysis of our financial condition and results of operations should be read together with the unaudited condensed consolidated financial statements and the related notes to those statements included as Exhibit 99.1 to this Report on Form 6-K submitted to the Securities a

November 2, 2023 EX-99.1

INDEX TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS Condensed Consolidated Balance Sheets as of September 30, 2023 (Unaudited) and December 31, 2022 2 Condensed Consolidated Statements of Operations and Comprehensive Loss for the Three and Nine Mont

Exhibit 99.1 INDEX TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS Condensed Consolidated Balance Sheets as of September 30, 2023 (Unaudited) and December 31, 2022 2 Condensed Consolidated Statements of Operations and Comprehensive Loss for the Three and Nine Months Ended September 30, 2023 and 2022 (Unaudited) 3 Condensed Consolidated Statements of Shareholders’ Equity for the Three and Nine Month

August 7, 2023 S-8

As filed with the U.S. Securities and Exchange Commission on August 7, 2023

S-8 As filed with the U.S. Securities and Exchange Commission on August 7, 2023 Registration No. 333- UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM S-8 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 Autolus Therapeutics plc (Exact name of registrant as specified in its charter) England and Wales Not applicable (State or other jurisdiction of Incorporation or

August 7, 2023 EX-FILING FEES

Filing Fee Table.

Exhibit 107 Calculation of Filing Fee Table Form S-8 (Form Type) Autolus Therapeutics plc (Exact Name of Registrant as Specified in its Charter) Table 1: Newly Registered Securities Security Type Security Class Title Fee Calculation Rule Amount Registered(1) Proposed Maximum Offering Price Per Unit Maximum Aggregate Offering Price Fee Rate Amount of Registration Fee Equity Ordinary shares, nominal value $0.

August 3, 2023 EX-99.3

1 Autolus Therapeutics Reports Second Quarter 2023 Financial Results and Operational Progress - Obe-cel, a potentially transformational treatment for relapsed/refractory (r/r) adult B-cell Acute Lymphoblastic Leukemia (ALL), on track for a Biologics

pressreleaseasofaugust03 1 Autolus Therapeutics Reports Second Quarter 2023 Financial Results and Operational Progress - Obe-cel, a potentially transformational treatment for relapsed/refractory (r/r) adult B-cell Acute Lymphoblastic Leukemia (ALL), on track for a Biologics License Application (BLA) submission to the US Food & Drug Administration (FDA) by end of 2023 - Pivotal FELIX data at ASCO s

August 3, 2023 EX-99.1

INDEX TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS Condensed Consolidated Balance Sheets as of June 30, 2023 (Unaudited) and December 31, 2022 2 Condensed Consolidated Statements of Operations and Comprehensive Loss for the Three and Six Months End

Exhibit 99.1 INDEX TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS Condensed Consolidated Balance Sheets as of June 30, 2023 (Unaudited) and December 31, 2022 2 Condensed Consolidated Statements of Operations and Comprehensive Loss for the Three and Six Months Ended June 30, 2023 and 2022 (Unaudited) 3 Condensed Consolidated Statements of Shareholders’ Equity for the Three and Six Months Ended June

August 3, 2023 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of August 2023 Commission File Number: 001-385

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of August 2023 Commission File Number: 001-38547 Autolus Therapeutics plc (Translation of registrant’s name into English) The MediaWorks 191 Wood Lane London W12 7FP United Kingdom (Address of pri

August 3, 2023 EX-99.2

MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS

Exhibit 99.2 MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS The following discussion and analysis of our financial condition and results of operations should be read together with the unaudited condensed consolidated financial statements and the related notes to those statements included as Exhibit 99.1 to this Report on Form 6-K submitted to the Securities a

July 21, 2023 EX-99.1

Autolus Therapeutics announces appointment of Robert F. Dolski as Chief Financial Officer July 19, 2023 at 7:00 AM EDT - Veronica Hersberger appointed as Senior Vice President, Medical Affairs - Miranda Neville promoted to Senior Vice President, Proj

pressreleasedatedjuly192 Autolus Therapeutics announces appointment of Robert F. Dolski as Chief Financial Officer July 19, 2023 at 7:00 AM EDT - Veronica Hersberger appointed as Senior Vice President, Medical Affairs - Miranda Neville promoted to Senior Vice President, Project Management and will continue to lead the obe-cel program LONDON, July 19, 2023 (GLOBE NEWSWIRE) - Autolus Therapeutics pl

July 21, 2023 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of July 2023 Commission File Number: 001-38547

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of July 2023 Commission File Number: 001-38547 Autolus Therapeutics plc (Translation of registrant’s name into English) The MediaWorks 191 Wood Lane London W12 7FP United Kingdom (Address of princ

July 10, 2023 EX-99.1

Joint Filing Agreement

Exhibit 1 JOINT FILING AGREEMENT In accordance with Rule 13d-1(k) under the Securities Exchange Act of 1934, as amended, the persons named below agree to the joint filing on behalf of each of them of a statement on Schedule 13G (including amendments thereto) with respect to the ordinary shares, nominal value $0.

July 10, 2023 SC 13G

AUTL / Autolus Therapeutics plc - ADR / Paradigm Biocapital Advisors LP - SC 13G Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* Autolus Therapeutics plc (Name of Issuer) Ordinary shares, nominal value $0.000042 per share** (Title of Class of Securities) 05280R100*** (CUSIP Number) June 30, 2023 (Date of Event Which Requires Filing of this statement) Check the appropriate box to de

July 7, 2023 6-K/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K/A REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of June 2023 Commission File Number: 001-385

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K/A REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of June 2023 Commission File Number: 001-38547 Autolus Therapeutics plc (Translation of registrant’s name into English) The MediaWorks 191 Wood Lane London W12 7FP United Kingdom (Address of pri

July 7, 2023 EX-99.1

EX-99.1

ex991annualreportandacco

July 7, 2023 EX-99.2

1 THIS DOCUMENT IS IMPORTANT AND REQUIRES YOUR IMMEDIATE ATTENTION. If you are in any doubt as to the action to be taken, please seek your own financial advice from your stockbroker, solicitor, accountant or other appropriately authorised independent

ex992noticeofannualgener 1 THIS DOCUMENT IS IMPORTANT AND REQUIRES YOUR IMMEDIATE ATTENTION.

July 6, 2023 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of June 2023 Commission File Number: 001-38547

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of June 2023 Commission File Number: 001-38547 Autolus Therapeutics plc (Translation of registrant’s name into English) The MediaWorks 191 Wood Lane London W12 7FP United Kingdom (Address of princ

June 20, 2023 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of June 2023 Commission File Number: 001-38547

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of June 2023 Commission File Number: 001-38547 Autolus Therapeutics plc (Translation of registrant’s name into English) The MediaWorks 191 Wood Lane London W12 7FP United Kingdom (Address of princ

June 20, 2023 EX-99.1

Autolus Therapeutics strengthens its Board with the appointment of Dr. Robert Iannone as a Non-Executive Director June 20, 2023 LONDON, June 20, 2023 (GLOBE NEWSWIRE) -- Autolus Therapeutics plc (Nasdaq: AUTL), a clinical-stage biopharmaceutical comp

pressreleasedatedjune202 Autolus Therapeutics strengthens its Board with the appointment of Dr.

June 6, 2023 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of June 2023 Commission File Number: 001-38547

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of June 2023 Commission File Number: 001-38547 Autolus Therapeutics plc (Translation of registrant’s name into English) The MediaWorks 191 Wood Lane London W12 7FP United Kingdom (Address of princ

June 6, 2023 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of June 2023 Commission File Number: 001-38547

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of June 2023 Commission File Number: 001-38547 Autolus Therapeutics plc (Translation of registrant’s name into English) The MediaWorks 191 Wood Lane London W12 7FP United Kingdom (Address of princ

June 6, 2023 EX-99.2

1 THIS DOCUMENT IS IMPORTANT AND REQUIRES YOUR IMMEDIATE ATTENTION. If you are in any doubt as to the action to be taken, please seek your own financial advice from your stockbroker, solicitor, accountant or other appropriately authorised independent

ex992noticeofannualgener 1 THIS DOCUMENT IS IMPORTANT AND REQUIRES YOUR IMMEDIATE ATTENTION.

June 6, 2023 EX-99.1

EX-99.1

ex991annualreportandacco

June 6, 2023 EX-99.3

MR A SAMPLE < DESIGNATION> SAMPLE STREET SAMPLE TOWN SAMPLE CITY SAMPLE COUNTY AA11 1AA MR A SAMPLE < Designation> Additional Holder 1 Additional Holder 2 Additional Holder 3 Additional Holder 4 Form of Proxy - Annual General Meeting to be held on 30

ex993formofproxy MR A SAMPLE < DESIGNATION> SAMPLE STREET SAMPLE TOWN SAMPLE CITY SAMPLE COUNTY AA11 1AA MR A SAMPLE < Designation> Additional Holder 1 Additional Holder 2 Additional Holder 3 Additional Holder 4 Form of Proxy - Annual General Meeting to be held on 30 June 2023 Kindly Note: This form is issued only to the addressee(s) and is specific to the unique designated account printed hereon.

June 6, 2023 EX-99.1

Autolus Therapeutics Presents Positive Results from Pivotal Phase 2 FELIX study in adult r/r B-ALL at ASCO June 2, 2023 76% of patients treated with obe-cel in the FELIX study achieved a response (CR/CRi), primary endpoint has been met based on previ

ex-991pressreleasedatedj Autolus Therapeutics Presents Positive Results from Pivotal Phase 2 FELIX study in adult r/r B-ALL at ASCO June 2, 2023 76% of patients treated with obe-cel in the FELIX study achieved a response (CR/CRi), primary endpoint has been met based on previously communicated interim analysis Potential best in class tolerability, with very low levels of high-grade CRS and ICANS Robust and reliable manufacturing and logistics, with 84% of enrolled patients receiving obe-cel Analyst call to be held today, June 2, 2023 at 4.

May 4, 2023 EX-99.2

MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS

Exhibit 99.2 MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS The following discussion and analysis of our financial condition and results of operations should be read together with the unaudited condensed consolidated financial statements and the related notes to those statements included as Exhibit 99.1 to this Report on Form 6-K submitted to the Securities a

May 4, 2023 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of May 2023 Commission File Number: 001-38547

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of May 2023 Commission File Number: 001-38547 Autolus Therapeutics plc (Translation of registrant’s name into English) The MediaWorks 191 Wood Lane London W12 7FP United Kingdom (Address of princi

May 4, 2023 EX-99.3

Autolus Therapeutics Reports First Quarter 2023 Financial Results and Operational Progress May 4, 2023 Obe-cel, a potentially transformational treatment for relapsed/refractory (r/r) B-cell Acute Lymphoblastic Leukemia (ALL), on track for next data u

pressrelease04may2023 Autolus Therapeutics Reports First Quarter 2023 Financial Results and Operational Progress May 4, 2023 Obe-cel, a potentially transformational treatment for relapsed/refractory (r/r) B-cell Acute Lymphoblastic Leukemia (ALL), on track for next data update at ASCO and EHA, with a Biologics License Application (BLA) submission to the US FDA planned by end of the year Establishi

May 4, 2023 EX-99.1

INDEX TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS Condensed Consolidated Balance Sheets as of March 31, 2023 (Unaudited) and December 31, 2022 2 Condensed Consolidated Statements of Operations and Comprehensive Loss for the Three Months Ended Marc

Exhibit 99.1 INDEX TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS Condensed Consolidated Balance Sheets as of March 31, 2023 (Unaudited) and December 31, 2022 2 Condensed Consolidated Statements of Operations and Comprehensive Loss for the Three Months Ended March 31, 2023 and 2022 (Unaudited) 3 Condensed Consolidated Statements of Shareholders’ Equity for the Three Months Ended March 31, 2023 and

March 20, 2023 SC 13G

AUTL / Autolus Therapeutics plc - ADR / Tetragon Financial Management LP - TETRAGON FINANCIAL MANAGEMENT LP Passive Investment

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* Autolus Therapeutics plc (Name of Issuer) Ordinary shares, nominal value $0.000042 per share (Title of Class of Securities) 05280R100** (CUSIP Number) March 9, 2023 (Date of Event Which Requires Filing of This Statement) Check the appropriate box to designate the rule

March 20, 2023 EX-99.1

JOINT ACQUISITION STATEMENT PURSUANT TO RULE 13d-1(k)

EXHIBIT 99.1 JOINT ACQUISITION STATEMENT PURSUANT TO RULE 13d-1(k) The undersigned acknowledge and agree that the foregoing statement on Schedule 13G is filed on behalf of each of the undersigned and that all subsequent amendments to this statement on Schedule 13G shall be filed on behalf of each of the undersigned without the necessity of filing additional joint acquisition statements. The unders

March 14, 2023 EX-99.1

Autolus Therapeutics announces resignation of Chief Financial Officer March 14, 2023 - Dr. Lucinda Crabtree to step down with effect from Q3 2023 – - Search for new CFO has been initiated - LONDON, March 14, 2023 (GLOBE NEWSWIRE) -- Autolus Therapeut

pressreleasedatedmarch14 Autolus Therapeutics announces resignation of Chief Financial Officer March 14, 2023 - Dr.

March 14, 2023 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of March 2023 Commission File Number: 001-3854

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of March 2023 Commission File Number: 001-38547 Autolus Therapeutics plc (Translation of registrant’s name into English) The MediaWorks 191 Wood Lane London W12 7FP United Kingdom (Address of prin

March 7, 2023 EX-12.2

Certification by the Principal Financial Officer pursuant to Securities Exchange Act Rules 13a-14(a) and 15d-14(a) as adopted pursuant to Section 302 of the Sarbanes-Oxley Act of 2002

Certification by the Principal Financial Officer pursuant to Securities Exchange Act Rules 13a-14(a) and 15d-14(a) as adopted pursuant to Section 302 of the Sarbanes-Oxley Act of 2002 I, Lucinda C.

March 7, 2023 20-F

Form 20-F

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 20-F (Mark One) o REGISTRATION STATEMENT PURSUANT TO SECTION 12(b) OR (g) OF THE SECURITIES EXCHANGE ACT OF 1934 OR x ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2022 OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXC

March 7, 2023 EX-12.1

Certification by the Principal Executive Officer pursuant to Securities Exchange Act Rules 13a-14(a) and 15d-14(a) as adopted pursuant to Section 302 of the Sarbanes-Oxley Act of 2002

Certification by the Principal Executive Officer pursuant to Securities Exchange Act Rules 13a-14(a) and 15d-14(a) as adopted pursuant to Section 302 of the Sarbanes-Oxley Act of 2002 I, Christian Itin, certify that: 1.

March 7, 2023 EX-15.1

Consent of Independent Registered Public Accounting Firm

Consent of Independent Registered Public Accounting Firm We consent to the incorporation by reference in the following Registration Statements: (1)Registration Statement (Form S-8 No.

March 7, 2023 EX-13.1

Certification by the Principal Executive Officer and Principal Financial Officer pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002

Certification by the Principal Executive Officer and Principal Financial Officer pursuant to 18 U.

March 1, 2023 EX-99.(E)

Rule 466 Certification

Exhibit (e) Rule 466 Certification The depositary, Citibank, N.A., represents and certifies the following: (i) That it previously had filed a registration statement on Form F-6 (Registration No. 333-260904), which the U.S. Securities and Exchange Commission declared effective, with terms of deposit identical to the terms of deposit of this Form F-6 Registration Statement and (ii) That its ability

March 1, 2023 EX-99.(B)(I)

Autolus Therapeutics plc

Exhibit (b)(i) Autolus Therapeutics plc As of November 16, 2021 Citibank, N.A. - ADR Department 388 Greenwich Street New York, New York 10013 Re: Restricted ADSs (CUSIP No.: 05280R993) Ladies and Gentlemen: Reference is made to the Deposit Agreement, dated as of June 26, 2018, as amended and supplemented from time to time (the “Deposit Agreement”), by and among Autolus Therapeutics plc, a public l

March 1, 2023 EX-99.(B)(III)

and Citibank, N.A. BLACKSTONE – WARRANT

Exhibit (b)(iii) SERIES EXHIBIT B to Restricted ADS Letter Agreement, dated as of November 16, 2021 (the “Restricted ADS Letter Agreement”), by and between Autolus Therapeutics plc and Citibank, N.

March 1, 2023 EX-99.(B)(II)

and Citibank, N.A. BLACKSTONE – PIPE SECURITIES PURCHASE AGREEMENT

Exhibit (b)(ii) SERIES EXHIBIT A to Restricted ADS Letter Agreement, dated as of November 16, 2021 (the “Restricted ADS Letter Agreement”), by and between Autolus Therapeutics plc and Citibank, N.

March 1, 2023 EX-99.(D)

Exhibit (d)

Exhibit (d) March 1, 2023 Citibank, N.A. – ADR Department 388 Greenwich Street New York, New York 10013 Ladies and Gentlemen: We refer to the Registration Statement on Form F-6 (the “Registration Statement”) to be filed with the Securities and Exchange Commission (the “SEC”) by the legal entity created by the Deposit Agreement (as hereinafter defined) for the purpose of registering under the Unite

March 1, 2023 F-6EF

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM F-6 REGISTRATION STATEMENT THE SECURITIES ACT OF 1933 FOR AMERICAN DEPOSITARY SHARES EVIDENCED BY AMERICAN DEPOSITARY RECEIPTS AUTOLUS THERAPEUTICS plc (Exact name of issuer of deposited

As filed with the Securities and Exchange Commission on March 1, 2023 Registration No.

February 14, 2023 SC 13G/A

AUTL / Autolus Therapeutics PLC / Deep Track Capital, LP Passive Investment

SC 13G/A 1 deeptrack-autl123122a1.htm UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 13G/A Under the Securities Exchange Act of 1934 (Amendment No. 1)* Autolus Therapeutics PLC (Name of Issuer) American Depositary Shares, each representing one ordinary share, nominal value $0.000042 per share (Title of Class of Securities) 05280R100 (CUSIP Number) December 31, 2022

February 14, 2023 SC 13G/A

AUTL / Autolus Therapeutics PLC / Nantahala Capital Management, LLC - SC 13G/A Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 1)* Autolus Therapeutics plc (Name of Issuer) American Depository Shares, each representing one ordinary share, nominal value $0.000042 per share (Title of Class of Securities) 05280R100 (CUSIP Number) December 31, 2022 (Date of Event which Requires Filing o

February 14, 2023 SC 13G/A

AUTL / Autolus Therapeutics PLC / Frazier Life Sciences Public Fund, L.P. - SC 13G/A Passive Investment

SC 13G/A 1 d437783dsc13ga.htm SC 13G/A SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 1)* Autolus Therapeutics plc (Name of Issuer) Ordinary Shares (Title of Class of Securities) 05280R100** (CUSIP Number) December 31, 2022 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate th

February 14, 2023 SC 13G

AUTL / Autolus Therapeutics PLC / ARMISTICE CAPITAL, LLC Passive Investment

SC 13G 1 armistice-autl123122.htm UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* Autolus Therapeutics, plc (Name of Issuer) American Depository Shares, each representing one ordinary share, nominal value $0.000042 per share (Title of Class of Securities) 05280R100 (CUSIP Number) December 31, 2022 (Date

February 14, 2023 EX-99.1

/s/ Martin Murphy Martin Murphy

EX-99.1 Exhibit 99.1 AGREEMENT In accordance with Rule 13d-1(k) under the Securities Exchange Act of 1934, as amended, the persons named below agree to the joint filing on behalf of each of them of a statement on Schedule 13G (including amendments thereto) with respect to the Ordinary Shares (represented by ADS, each of which represents one Ordinary Share) of Autolus Therapeutics plc and further a

February 14, 2023 SC 13G/A

AUTL / Autolus Therapeutics PLC / Syncona Portfolio Ltd - SC 13G/A Passive Investment

SC 13G/A 1 d411686dsc13ga.htm SC 13G/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 5)* Autolus Therapeutics plc (Name of Issuer) American Depositary Shares and Ordinary Shares, nominal value $0.000042 per share (Title of Class of Securities) 05280R 100** (CUSIP Number) December 31, 2022 (Date of Event

February 13, 2023 SC 13G/A

AUTL / Autolus Therapeutics PLC / Capital World Investors - SEC SCHEDULE 13G Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 1 )* Autolus Therapeutics PLC (Name of Issuer) Common Stock (Title of Class of Securities) 05280R100 (CUSIP Number) December 30, 2022 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which th

January 23, 2023 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of January 2023 Commission File Number: 001-38

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of January 2023 Commission File Number: 001-38547 Autolus Therapeutics plc (Translation of registrant’s name into English) The MediaWorks 191 Wood Lane London W12 7FP United Kingdom (Address of pr

January 23, 2023 EX-99.1

Autolus Therapeutics announces Board changes January 20, 2023 LONDON, Jan. 20, 2023 (GLOBE NEWSWIRE) -- Autolus Therapeutics plc (Nasdaq: AUTL), a clinical-stage biopharmaceutical company developing next-generation programmed T cell therapies, announ

pressreleasedatedjanuary Autolus Therapeutics announces Board changes January 20, 2023 LONDON, Jan.

December 21, 2022 EX-99.1

Autolus Announces Partial Exercise of Underwriters’ Option to Purchase Additional ADSs

Exhibit 99.1 Autolus Announces Partial Exercise of Underwriters? Option to Purchase Additional ADSs LONDON ? 21 December 2022 ? Autolus Therapeutics plc (Nasdaq: AUTL), a clinical-stage biopharmaceutical company developing next-generation programmed T cell therapies, announced today that the underwriters of its previously announced public offering of American Depositary Shares, or ADSs, which clos

December 21, 2022 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of December 2022 Commission File Number: 001-3

6-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of December 2022 Commission File Number: 001-38547 Autolus Therapeutics plc (Translation of registrant’s name into English) The MediaWorks 191 Wood Lane London W12 7FP United Kingdom (Address

December 19, 2022 SC 13G

AUTL / Autolus Therapeutics PLC / Deep Track Capital, LP Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No.

December 13, 2022 SC 13D/A

AUTL / Autolus Therapeutics PLC / Blackstone Group Inc - SC 13D/A Activist Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D Under the Securities Exchange Act of 1934 (Amendment No. 1)* Autolus Therapeutics plc (Name of Issuer) American Depositary Shares, each representing one ordinary share, nominal value $0.000042 per share (Title of Class of Securities) 05280R100 ** (CUSIP Number) John G. Finley Blackstone Inc. 345 Park Avenue New Yo

December 13, 2022 EX-99.A

EXHIBIT A

EXHIBIT A The Schedule 13G to which this attachment is appended is filed by Qatar Investment Authority on behalf of itself and the following subsidiaries: Qatar Holding LLC

December 13, 2022 SC 13G

AUTL / Autolus Therapeutics PLC / Qatar Investment Authority - ACQUISITION OF BENEFICIAL OWNERSHIP Passive Investment

SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. ) * AUTOLUS THERAPEUTICS PLC (Name of Issuer) American Depositary Shares, each representing one ordinary share, par value $0.000042 per share (Title of Class of Securities) 05280R100** (CUSIP Number) December 9, 2022 (Date of Event Which Requires Filing this Statement) Ch

December 13, 2022 EX-99.B

CERTIFICATE OF INCUMBENCY

EXHIBIT B CERTIFICATE OF INCUMBENCY I, Ahmad Mohammed F Q Al-Khanji, Chief of Legal and General Counsel, of Qatar Investment Authority, established by Emiri Decision No 22 in 2005, with its registered office at, Ooredoo Tower (Building 14), Al Dafna Street (Street 801), Al Dafna (Zone 61), Doha, State of Qatar, do hereby confirm that Andrew Watkins is the duly appointed Associate General Counsel, Compliance, an officer of the Qatar Investment Authority, and as such, is authorized to sign regulatory filings on behalf of the Qatar Investment Authority.

December 12, 2022 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of December 2022 Commission File Number: 001-3

6-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of December 2022 Commission File Number: 001-38547 Autolus Therapeutics plc (Translation of registrant’s name into English) The MediaWorks 191 Wood Lane London W12 7FP United Kingdom (Address

December 12, 2022 424B5

75,000,000 American Depositary Shares Representing 75,000,000 Ordinary Shares

424B5 Table of Contents Filed pursuant to Rule 424(b)(5) Registration No. 333-258556 PROSPECTUS SUPPLEMENT (To Prospectus Dated August 19, 2021) 75,000,000 American Depositary Shares Representing 75,000,000 Ordinary Shares We are offering 75,000,000 of our American Depositary Shares, or ADSs. Each ADS represents one ordinary share with a nominal value of $0.000042 per share. The ADSs may be eviden

December 12, 2022 EX-1.1

Underwriting Agreement, dated as of December 8, 2022, among the Company and Jefferies LLC, William Blair & Company, L.L.C. and Wells Fargo Securities, LLC, as representatives of the several underwriters named therein.

EX-1.1 Exhibit 1.1 Autolus Therapeutics plc American Depositary Shares Representing Ordinary Shares Underwriting Agreement December 8, 2022 Jefferies LLC William Blair & Company, L.L.C. Wells Fargo Securities, LLC as representatives (the “Representatives”) of the several Underwriters named in Schedule I hereto Jefferies LLC 520 Madison Avenue New York, New York 10022 William Blair & Company, L.L.C

December 12, 2022 EX-99.1

Autolus Announces Pricing of Public Offering

EX-99.1 Exhibit 99.1 Autolus Announces Pricing of Public Offering LONDON – 8 December 2022 – Autolus Therapeutics plc (Nasdaq: AUTL), a clinical-stage biopharmaceutical company developing next-generation programmed T cell therapies, today announced the pricing of its previously announced underwritten public offering in the United States of 75,000,000 American Depositary Shares (“ADSs”) representin

December 8, 2022 424B5

SUBJECT TO COMPLETION, DATED DECEMBER 8, 2022

424B5 Table of Contents Filed Pursuant to Rule 424(b)(5) Registration File No. 333-258556 The information in this preliminary prospectus supplement is not complete and may be changed. A registration statement relating to these securities has been filed with the Securities and Exchange Commission and is effective. This preliminary prospectus supplement and the accompanying prospectus are not an off

December 8, 2022 EX-99.1

Material U.S. Federal Income Tax Considerations for U.S. Holders

EX-99.1 Exhibit 99.1 TAXATION The following summary contains a description of material U.K. and U.S. federal income tax consequences of the acquisition, ownership and disposition of our ADSs. This summary should not be considered a comprehensive description of all the tax considerations that may be relevant to beneficial owners of ADSs. Material U.S. Federal Income Tax Considerations for U.S. Hold

December 8, 2022 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of December 2022 Commission File Number: 001-3

6-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of December 2022 Commission File Number: 001-38547 Autolus Therapeutics plc (Translation of registrant’s name into English) The MediaWorks 191 Wood Lane London W12 7FP United Kingdom (Address

December 8, 2022 EX-99.2

Autolus Announces Proposed Public Offering in the United States

EX-99.2 Exhibit 99.2 Autolus Announces Proposed Public Offering in the United States LONDON – 8 December 2022 – Autolus Therapeutics plc (Nasdaq: AUTL), a clinical-stage biopharmaceutical company developing next-generation programmed T cell therapies, today announced that it has commenced an underwritten public offering of American Depositary Shares (“ADSs”), each ADS representing one ordinary sha

November 21, 2022 6-K/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K/A REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of November 2022 Commission File Number: 001

6-K/A 1 autolus-300920226ka.htm 6-K/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K/A REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of November 2022 Commission File Number: 001-38547 Autolus Therapeutics plc (Translation of registrant’s name into English) The MediaWorks 191 Wood Lane Lon

November 21, 2022 EX-99.2

MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS

Exhibit 99.2 MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS The following discussion and analysis of our financial condition and results of operations should be read together with the unaudited condensed consolidated financial statements and the related notes to those statements included as Exhibit 99.1 to this Report on Form 6-K submitted to the Securities a

November 3, 2022 EX-99.3

1 Autolus Therapeutics Reports Third Quarter 2022 Financial Results and Operational Progress - Pivotal FELIX Phase 2 clinical trial of obe-cel in relapsed/refractory (r/r) Acute Lymphoblastic Leukemia (ALL) on track for Q4 2022 update - Commercial ma

1 Autolus Therapeutics Reports Third Quarter 2022 Financial Results and Operational Progress - Pivotal FELIX Phase 2 clinical trial of obe-cel in relapsed/refractory (r/r) Acute Lymphoblastic Leukemia (ALL) on track for Q4 2022 update - Commercial manufacturing site build on schedule for handover of first clean rooms to Autolus in Q4 2022 - Post-period end announcements: Bristol Myers Squibb licen

November 3, 2022 EX-99.2

MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS

Exhibit 99.2 MANAGEMENT?S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS The following discussion and analysis of our financial condition and results of operations should be read together with the unaudited condensed consolidated financial statements and the related notes to those statements included as Exhibit 99.1 to this Report on Form 6-K submitted to the Securities a

November 3, 2022 EX-99.1

INDEX TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS Condensed Consolidated Balance Sheets as of September 30, 2022 and December 31, 2021 (Unaudited) 2 Condensed Consolidated Statements of Operations and Comprehensive Loss for the Three and Nine Mont

Exhibit 99.1 INDEX TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS Condensed Consolidated Balance Sheets as of September 30, 2022 and December 31, 2021 (Unaudited) 2 Condensed Consolidated Statements of Operations and Comprehensive Loss for the Three and Nine Months Ended September 30, 2022 and 2021 (Unaudited) 3 Condensed Consolidated Statements of Shareholders? Equity for the Three and Nine Month

November 3, 2022 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of November 2022 Commission File Number: 001-3

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of November 2022 Commission File Number: 001-38547 Autolus Therapeutics plc (Translation of registrant’s name into English) The MediaWorks 191 Wood Lane London W12 7FP United Kingdom (Address of p

October 5, 2022 SC 13D/A

AUTL / Autolus Therapeutics PLC / PPF Capital Partners Fund B.V. - AMENDMENT NO. 8 TO SCHEDULE 13D Activist Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D Under the Securities Exchange Act of 1934 (Amendment No. 8) AUTOLUS THERAPEUTICS PLC (Name of Issuer) American Depositary Shares, each representing one ordinary share, nominal value $0.000042 per share, and ordinary shares, nominal value $0.000042 per share (Title of Class of Securities) 05280R100** (CUSIP Number)

August 4, 2022 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of August 2022 Commission File Number: 001-385

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of August 2022 Commission File Number: 001-38547 Autolus Therapeutics plc (Translation of registrant?s name into English) The MediaWorks 191 Wood Lane London W12 7FP United Kingdom (Address of pri

August 4, 2022 EX-99.1

INDEX TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS Condensed Consolidated Balance Sheets as of June 30, 2022 and December 31, 2021 (Unaudited) 2 Condensed Consolidated Statements of Operations and Comprehensive Loss for the Three and Six Months End

Exhibit 99.1 INDEX TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS Condensed Consolidated Balance Sheets as of June 30, 2022 and December 31, 2021 (Unaudited) 2 Condensed Consolidated Statements of Operations and Comprehensive Loss for the Three and Six Months Ended June 30, 2022 and 2021 (Unaudited) 3 Condensed Consolidated Statements of Shareholders? Equity for the Three and Six Months Ended June

August 4, 2022 EX-99.3

Autolus Therapeutics Reports Second Quarter 2022 Financial Results and Operational Progress August 4, 2022 - Conference call to be held on August 4, 2022 at 8:30 am ET/1:30 pm BST - LONDON, Aug. 04, 2022 (GLOBE NEWSWIRE) -- Autolus Therapeutics plc (

Autolus Therapeutics Reports Second Quarter 2022 Financial Results and Operational Progress August 4, 2022 - Conference call to be held on August 4, 2022 at 8:30 am ET/1:30 pm BST - LONDON, Aug.

August 4, 2022 EX-99.2

MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS

Exhibit 99.2 MANAGEMENT?S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS The following discussion and analysis of our financial condition and results of operations should be read together with the unaudited condensed consolidated financial statements and the related notes to those statements included as Exhibit 99.1 to this Report on Form 6-K submitted to the Securities a

July 1, 2022 EX-1

Annual Report and Accounts for the 12-month period ended December 31, 2021

Registered Number 11185179 (England & Wales) Annual Report and Accounts for the year ended 31 December 2021 for Autolus Therapeutics plc AUTOLUS THERAPEUTICS PLC Introduction and Contents Autolus Therapeutics plc (the ?Company?, ?Group? or ?Parent Company?) is a public limited company incorporated under the laws of England and Wales and is listed on the Nasdaq Global Select Market (?NASDAQ?).

July 1, 2022 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of June 2022 Commission File Number: 001-38547

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of June 2022 Commission File Number: 001-38547 Autolus Therapeutics plc (Translation of registrant?s name into English) The MediaWorks 191 Wood Lane London W12 7FP United Kingdom (Address of princ

June 1, 2022 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 OF THE SECURITIES EXCHANGE ACT OF 1934 For the month of June 2022 (Commission File No. 001-38547) Auto

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 OF THE SECURITIES EXCHANGE ACT OF 1934 For the month of June 2022 (Commission File No. 001-38547) Autolus Therapeutics plc (Translation of registrant?s name into English) The MediaWorks 191 Wood Lane London W12 7FP United Kingdom (Address of registrant

June 1, 2022 EX-99.1

1

Exhibit 99.1 THIS DOCUMENT IS IMPORTANT AND REQUIRES YOUR IMMEDIATE ATTENTION. If you are in any doubt as to the action to be taken, please seek your own financial advice from your stockbroker, solicitor, accountant or other appropriately authorised independent financial adviser. If you have recently sold or transferred all of your shares in Autolus Therapeutics plc, you should forward this docume

May 18, 2022 424B3

12,180,333 American Depositary Shares Representing 12,180,333 Ordinary Shares

Table of Contents Filed Pursuant to Rule 424(b)(3) Registration No. 333-264650 PROSPECTUS 12,180,333 American Depositary Shares Representing 12,180,333 Ordinary Shares This prospectus relates to the resale by the selling securityholders identified in this prospectus, or the selling securityholders, of up to 12,180,333 American Depositary Shares, or ADSs, representing 12,180,333 ordinary shares of

May 13, 2022 CORRESP

The MediaWorks 191 Wood Lane White City London W12 7FP United Kingdom VIA EDGAR

The MediaWorks 191 Wood Lane White City London W12 7FP United Kingdom VIA EDGAR May 13, 2022 U.

May 5, 2022 EX-99.3

Material U.S. Federal Income Tax Considerations for U.S. Holders

Exhibit 99.3 TAXATION The following summary contains a description of material U.K. and U.S. federal income tax consequences of the acquisition, ownership and disposition of our ADSs. This summary should not be considered a comprehensive description of all the tax considerations that may be relevant to beneficial owners of ADSs Material U.S. Federal Income Tax Considerations for U.S. Holders The f

May 5, 2022 EX-99.2

MANAGEMENT’S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS

Exhibit 99.2 MANAGEMENT?S DISCUSSION AND ANALYSIS OF FINANCIAL CONDITION AND RESULTS OF OPERATIONS The following discussion and analysis of our financial condition and results of operations should be read together with the unaudited condensed consolidated financial statements and the related notes to those statements included as Exhibit 99.1 to this Report on Form 6-K submitted to the Securities a

May 5, 2022 EX-99.1

INDEX TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS Condensed Consolidated Balance Sheets as of March 31, 2022 and December 31, 2021 (Unaudited) 2 Condensed Consolidated Statements of Operations and Comprehensive Loss for the Three Months Ended Marc

Exhibit 99.1 INDEX TO CONDENSED CONSOLIDATED FINANCIAL STATEMENTS Condensed Consolidated Balance Sheets as of March 31, 2022 and December 31, 2021 (Unaudited) 2 Condensed Consolidated Statements of Operations and Comprehensive Loss for the Three Months Ended March 31, 2022 and 2021 (Unaudited) 3 Condensed Consolidated Statements of Shareholders? Equity for the Three Months Ended March 31, 2022 and

May 5, 2022 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of May 2022 Commission File Number: 001-38547

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the Month of May 2022 Commission File Number: 001-38547 Autolus Therapeutics plc (Translation of registrant?s name into English) The MediaWorks 191 Wood Lane London W12 7FP United Kingdom (Address of princi

May 4, 2022 F-3

As filed with the Securities and Exchange Commission on May 3, 2022

Table of Contents As filed with the Securities and Exchange Commission on May 3, 2022 Registration No.

May 4, 2022 EX-FILING FEES

Filing Fee Table

Exhibit 107 Calculation of Filing Fee Table Form F-3 (Form Type) Autolus Therapeutics plc (Exact Name of Registrant as Specified in its Charter) Table 1: Newly Registered Securities Security Type Security Class Title Fee Calculation Rule Amount Registered(1)(2) Proposed Maximum Offering Price Per Unit Maximum Aggregate Offering Price Fee Rate Amount of Registration Fee(6) Equity American Depositary Shares (ADSs) 457(c) 12,180,333 $3.

May 3, 2022 424B3

21,250,917 American Depositary Shares Representing 21,250,917 Ordinary Shares

Table of Contents Filed Pursuant to Rule 424(b)(3) Registration No. 333-264304 PROSPECTUS 21,250,917 American Depositary Shares Representing 21,250,917 Ordinary Shares This prospectus relates to the resale by the selling securityholders identified in this prospectus, or the selling securityholders, of up 21,250,917 American Depositary Shares, or ADSs, representing 21,250,917 ordinary shares of Aut

April 26, 2022 CORRESP

The MediaWorks 191 Wood Lane White City London W12 7FP United Kingdom VIA EDGAR

The MediaWorks 191 Wood Lane White City London W12 7FP United Kingdom VIA EDGAR April 26, 2022 U.

April 15, 2022 EX-FILING FEES

Filing Fee Table

Exhibit 107 Calculation of Filing Fee Table Form F-3 (Form Type) Autolus Therapeutics plc (Exact Name of Registrant as Specified in its Charter) Table 1: Newly Registered Securities Security Type Security Class Title Fee Calculation Rule Amount Registered(1)(2) Proposed Maximum Offering Price Per Unit Maximum Aggregate Offering Price Fee Rate Amount of Registration Fee(6) Equity American Depositary Shares (ADSs) 457(c) 21,250,917 $4.

April 15, 2022 F-3

As filed with the Securities and Exchange Commission on April 14, 2022

Table of Contents As filed with the Securities and Exchange Commission on April 14, 2022 Registration No.

March 10, 2022 EX-15.1

Consent of Independent Registered Public Accounting Firm

Consent of Independent Registered Public Accounting Firm We consent to the incorporation by reference in the following Registration Statements: (1)Registration Statement (Form S-8 No.

March 10, 2022 20-F

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 20-F (Mark One) o REGISTRATION STATEMENT PURSUANT TO SECTION 12(b) OR (g) OF THE SECURITIES EXCHANGE ACT OF 1934 x ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECUR

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 20-F (Mark One) o REGISTRATION STATEMENT PURSUANT TO SECTION 12(b) OR (g) OF THE SECURITIES EXCHANGE ACT OF 1934 OR x ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2021 OR o TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXC

March 10, 2022 EX-4.7

Collaboration and Financing Agreement, dated as of November 6, 2021, between Autolus Limited and BXLS V — Autobahn L.P.

ACTIVE/115687690.3 CERTAIN CONFIDENTIAL INFORMATION CONTAINED IN THIS DOCUMENTS, MARKED BY [***], HAS BEEN OMITTED BECAUSE IT IS NOT MATERIAL AND WOULD LIKELY CAUSE COMPETITIVE HARM TO THE COMPANY IF PUBLICLY DISCLOSED. -i- COLLABORATION AND FINANCING AGREEMENT by and between AUTOLUS LIMITED AND BXLS V ? AUTOBAHN L.P. ACTIVE/115687690.3 CERTAIN CONFIDENTIAL INFORMATION CONTAINED IN THIS DOCUMENTS,

March 10, 2022 EX-12.1

Certification by the Principal Executive Officer pursuant to Securities Exchange Act Rules 13a-14(a) and 15d-14(a) as adopted pursuant to Section 302 of the Sarbanes-Oxley Act of 2002

Certification by the Principal Executive Officer pursuant to Securities Exchange Act Rules 13a-14(a) and 15d-14(a) as adopted pursuant to Section 302 of the Sarbanes-Oxley Act of 2002 I, Christian Itin, certify that: 1.

March 10, 2022 EX-12.2

Certification by the Principal Financial Officer pursuant to Securities Exchange Act Rules 13a-14(a) and 15d-14(a) as adopted pursuant to Section 302 of the Sarbanes-Oxley Act of 2002

Certification by the Principal Financial Officer pursuant to Securities Exchange Act Rules 13a-14(a) and 15d-14(a) as adopted pursuant to Section 302 of the Sarbanes-Oxley Act of 2002 I, Andrew J.

March 10, 2022 EX-13.1

Certification by the Principal Executive Officer and Principal Financial Officer pursuant to 18 U.S.C. Section 1350, as adopted pursuant to Section 906 of the Sarbanes-Oxley Act of 2002

Certification by the Principal Executive Officer and Principal Financial Officer pursuant to 18 U.

February 14, 2022 SC 13G

AUTL / Autolus Therapeutics PLC / Nantahala Capital Management, LLC - SC 13G Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* Autolus Therapeutics plc (Name of Issuer) American Depositary Shares and Ordinary Shares, nominal value $0.000042 per share (Title of Class of Securities) 05280R100 (CUSIP Number) December 31, 2021 (Date of Event which Requires Filing of this Statement) C

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