VRNA / Verona Pharma plc - Depositary Receipt (Common Stock) - Pengajuan SECLaporan Tahunan, Pernyataan Proksi

Verona Pharma plc - Depositary Receipt (Common Stock)
US ˙ NasdaqGM ˙ US9250501064

Mga Batayang Estadistika
LEI 213800EVI6O6J3TIAL06
CIK 1657312
SEC Filings
All companies that sell securities in the United States must register with the Securities and Exchange Commission (SEC) and file reports on a regular basis. These reports include company annual reports (10K, 10Q), news updates (8K), investor presentations (found in 8Ks), insider trades (form 4), ownership reports (13D, and 13G), and reports related to the specific securities sold, such as registration statements and prospectus. This page shows recent SEC filings related to Verona Pharma plc - Depositary Receipt (Common Stock)
SEC Filings (Chronological Order)
Halaman ini menyediakan daftar lengkap dan kronologis dari Pengajuan SEC, tidak termasuk pengajuan kepemilikan yang kami sediakan di tempat lain.
August 18, 2025 DEFM14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (RULE 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

TABLE OF CONTENTS UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (RULE 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confid

August 6, 2025 EX-10.2

First Amendment to Collaboration and License Agreement, dated November 18, 2024, by and between Verona Pharma plc, Nuance Pharma Limited and Nuance (Shanghai) Pharma Co Ltd

Exhibit 10.2 CERTAIN INFORMATION IN THIS DOCUMENT, MARKED BY [***], HAS BEEN EXCLUDED PURSUANT TO REGULATION S-K, ITEM 601(b)(10)(iv). SUCH EXCLUDED INFORMATION IS NOT MATERIAL AND IS THE TYPE THAT THE REGISTRANT TREATS AS PRIVATE OR CONFIDENTIAL. FIRST AMENDMENT TO COLLABORATION AND LICENSE AGREEMENT This First Amendment to Collaboration and License Agreement (the “Amendment”) is entered into by

August 6, 2025 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2025 ☐ TRANSITION REPORT PURSUANT TO S

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2025 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 FOR THE TRANSITION PERIOD FROM TO Commission File Number: 001-38067 Verona Pharma plc (Ex

August 5, 2025 PREM14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (RULE 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

TABLE OF CONTENTS UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (RULE 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant ☒ Filed by a Party other than the Registrant ☐ Check the appropriate box: ☒ Preliminary Proxy Statement ☐ Confid

August 5, 2025 EX-FILING FEES

Table 1: Transaction Valuation

Calculation of Filing Fee Tables Table 1: Transaction Valuation Proposed Maximum Aggregate Value of Transaction Fee Rate Amount of Filing Fee Fees to be Paid 1 $ 10,050,049,460.

July 30, 2025 DFAN14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 (AMENDMENT NO.  )

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 (AMENDMENT NO.  ) Filed by the Registrant ☐ Filed by a Party other than the Registrant ☒ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule14a-6

July 30, 2025 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (RULE 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (RULE 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant x Filed by a Party other than the Registrant ¨ Check the appropriate box: ¨ Preliminary Proxy Statement ¨ Confidential, for Use of

July 10, 2025 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (RULE 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (RULE 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant x Filed by a Party other than the Registrant ¨ Check the appropriate box: ¨ Preliminary Proxy Statement ¨ Confidential, for Use of

July 10, 2025 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (RULE 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (RULE 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant x Filed by a Party other than the Registrant ¨ Check the appropriate box: ¨ Preliminary Proxy Statement ¨ Confidential, for Use of

July 9, 2025 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (RULE 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (RULE 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 Filed by the Registrant x Filed by a Party other than the Registrant ¨ Check the appropriate box: ¨ Preliminary Proxy Statement ¨ Confidential, for Use of

July 9, 2025 EX-99.1

Press Release, dated July 9, 2025, jointly issued by Verona Pharma plc and Merck.

Exhibit 99.1 News Release Merck to Acquire Verona Pharma, Expanding its Portfolio to Include Ohtuvayre® (ensifentrine), a First-In-Class COPD Maintenance Treatment for Adults and Expected to Drive Growth into the Next Decade Acquisition aligns with Merck’s science-led business development strategy and expands pipeline and portfolio of treatments for cardio-pulmonary diseases Merck to hold investor

July 9, 2025 EX-2.1

Transaction Agreement, dated as of July 8, 2025, by and among Verona Pharma, Merck and Vol Holdings LLC.

Exhibit 2.1 TRANSACTION AGREEMENT by and among MERCK SHARP & DOHME LLC, VOL HOLDINGS LLC and VERONA PHARMA PLC Dated as of July 8, 2025 TABLE OF CONTENTS Page Article I DEFINITIONS & INTERPRETATIONS 4 Section 1.1 Certain Definitions 4 Section 1.2 Additional Definitions 18 Section 1.3 Certain Interpretations 19 Article II THE TRANSACTION 20 Section 2.1 The Transaction 20 Section 2.2 Closing 20 Sect

July 9, 2025 EX-2.1

Transaction Agreement, dated as of July 8, 2025, by and among Verona Pharma, Merck and Vol Holdings LLC.*

Exhibit 2.1 TRANSACTION AGREEMENT by and among MERCK SHARP & DOHME LLC, VOL HOLDINGS LLC and VERONA PHARMA PLC Dated as of July 8, 2025 TABLE OF CONTENTS Page Article I DEFINITIONS & INTERPRETATIONS 4 Section 1.1 Certain Definitions 4 Section 1.2 Additional Definitions 18 Section 1.3 Certain Interpretations 19 Article II THE TRANSACTION 20 Section 2.1 The Transaction 20 Section 2.2 Closing 20 Sect

July 9, 2025 DFAN14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 (AMENDMENT NO.  )

DFAN14A UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 (AMENDMENT NO.  ) Filed by the Registrant ☐ Filed by a Party other than the Registrant ☒ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by R

July 9, 2025 EX-99.1

Merck to Acquire Verona Pharma, Expanding its Portfolio to Include Ohtuvayre® (ensifentrine), a First-In-Class COPD Maintenance Treatment for Adults and Expected to Drive Growth into the Next Decade Acquisition aligns with Merck’s science-led busines

Exhibit 99.1 News Release Merck to Acquire Verona Pharma, Expanding its Portfolio to Include Ohtuvayre® (ensifentrine), a First-In-Class COPD Maintenance Treatment for Adults and Expected to Drive Growth into the Next Decade Acquisition aligns with Merck’s science-led business development strategy and expands pipeline and portfolio of treatments for cardio-pulmonary diseases Merck to hold investor

July 9, 2025 DFAN14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 (AMENDMENT NO. )

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 (AMENDMENT NO. ) Filed by the Registrant ☐ Filed by a Party other than the Registrant ☒ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule14a-6(

July 9, 2025 DFAN14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 (AMENDMENT NO.  )

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 14A (Rule 14a-101) PROXY STATEMENT PURSUANT TO SECTION 14(a) OF THE SECURITIES EXCHANGE ACT OF 1934 (AMENDMENT NO.  ) Filed by the Registrant ☐ Filed by a Party other than the Registrant ☒ Check the appropriate box: ☐ Preliminary Proxy Statement ☐ Confidential, for Use of the Commission Only (as permitted by Rule14a-6

July 9, 2025 EX-10.1

Voting Agreement, dated as of July 8, 2025, by and among Verona Pharma, Merck and the shareholders party thereto.

Exhibit 10.1 CONFIDENTIAL Execution Version VOTING AGREEMENT This Voting Agreement (this “Agreement”) is made and entered into as of July 8, 2025 (the “Agreement Date”), by and among Merck Sharp & Dohme LLC, a New Jersey limited liability company (“Parent”), Verona Pharma plc, a public limited company incorporated under the laws of England and Wales (the “Company”) and each of the shareholders of

July 9, 2025 DEFA14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 8, 2025 Verona Pharma plc (Exa

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 8, 2025 Verona Pharma plc (Exact Name of Registrant as Specified in its Charter) United Kingdom 001-38067 98-1489389 (State or other jurisdiction of incorporation) (Commission File Number) (IRS Employer Identification No.

July 9, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 8, 2025 Verona Pharma plc (Exa

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, DC 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): July 8, 2025 Verona Pharma plc (Exact Name of Registrant as Specified in its Charter) United Kingdom 001-38067 98-1489389 (State or other jurisdiction of incorporation) (Commission File Number) (IRS Employer Identification No.

July 9, 2025 EX-10.1

Voting Agreement, dated as of July 8, 2025, by and among Verona Pharma, Merck and the shareholders party thereto.

Exhibit 10.1 CONFIDENTIAL Execution Version VOTING AGREEMENT This Voting Agreement (this “Agreement”) is made and entered into as of July 8, 2025 (the “Agreement Date”), by and among Merck Sharp & Dohme LLC, a New Jersey limited liability company (“Parent”), Verona Pharma plc, a public limited company incorporated under the laws of England and Wales (the “Company”) and each of the shareholders of

April 29, 2025 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): April 29, 2025 Verona Pharma plc (Exact name of registrant as specified in its charter) United Kingdom 001-38067 98-1489389 (State or other jurisdiction of incorporation) (Commission

April 29, 2025 EX-10.2

Form of Option Agreement pursuant to the Verona Pharma plc 2017 Second Amended and Restated Incentive Award Plan

US-DOCS\159194159.2 VERONA PHARMA PLC 2017 SECOND AMENDED AND RESTATED INCENTIVE AWARD PLAN OPTION GRANT NOTICE Capitalized terms not specifically defined in this Option Grant Notice (the “Grant Notice”) have the meanings given to them in the Second Amended and Restated 2017 Incentive Award Plan (as amended and/or restated from time to time, and together with any Sub-Plan thereunder, the “Plan”) o

April 29, 2025 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2025 ☐ TRANSITION REPORT PURSUANT TO

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2025 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 FOR THE TRANSITION PERIOD FROM TO Commission File Number: 001-38067 Verona Pharma plc (E

April 29, 2025 EX-10.3

Form of Restricted Share Unit Agreement pursuant to the Verona Pharma plc 2017 Second Amended and Restated Incentive Award Plan

rsugrantnoticeandagreeme US-DOCS\159194157.2 RESTRICTED SHARE UNIT GRANT NOTICE Capitalized terms not specifically defined in this Restricted Share Unit Grant Notice (the “Grant Notice”) have the meanings given to them in the Second Amended and Restated 2017 Incentive Award Plan (as amended and/or restated from time to time, and together with any Sub-Plan thereunder, the “Plan”) of Verona Pharma p

April 29, 2025 EX-99.1

Verona Pharma Reports First Quarter 2025 Financial Results and Provides Corporate Update Total net revenue of $76.3 million from Q1 2025 driven by Ohtuvayre® net sales of $71.3 million (+95% vs Q4 2024) ~25,000 prescriptions filled in Q1 2025 Q1 2025

Verona Pharma Reports First Quarter 2025 Financial Results and Provides Corporate Update Total net revenue of $76.

April 29, 2025 EX-10.4

Form of Performance Restricted Share Unit Agreement pursuant to the Verona Pharma plc 2017 Second Amended and Restated Incentive Award Plan

US-DOCS\80100753.1 VERONA PHARMA PLC SECOND AMENDED AND RESTATED 2017 INCENTIVE AWARD PLAN PERFORMANCE RESTRICTED SHARE UNIT GRANT NOTICE Capitalized terms not specifically defined in this Performance Restricted Share Unit Grant Notice (the “Grant Notice”) have the meanings given to them in the Second Amended and Restated 2017 Incentive Award Plan (as amended and/or restated from time to time, and

April 25, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): April 24, 2025 Verona Pharma plc

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): April 24, 2025 Verona Pharma plc (Exact name of registrant as specified in its charter) United Kingdom 001-38067 98-1489389 (State or other jurisdiction of incorporation) (Commission

March 28, 2025 EX-99.1

Verona Pharma Announces Amended Strategic Financing with Oaktree and OMERS RIPSA interests repurchased Term loan facility increased to $450 million with more favorable terms Access to up to an additional $200 million

Exhibit 99.1 Verona Pharma Announces Amended Strategic Financing with Oaktree and OMERS RIPSA interests repurchased Term loan facility increased to $450 million with more favorable terms Access to up to an additional $200 million LONDON and RALEIGH, N.C., March 28, 2025 – Verona Pharma plc (Nasdaq: VRNA) (“Verona Pharma” or the “Company”), a biopharmaceutical company focused on respiratory disease

March 28, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): March 25, 2025 Verona Pharma plc

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): March 25, 2025 Verona Pharma plc (Exact name of registrant as specified in its charter) United Kingdom 001-38067 98-1489389 (State or other jurisdiction of incorporation) (Commission

March 28, 2025 EX-10.1

First Amendment to Credit Agreement and Guaranty, dated as of March 27, 2025, by and among the Company, Verona Pharma, Inc., Oaktree Fund Administration, LLC, as administrative agent, and the lenders party thereto.

Exhibit 10.1 Execution Version [***] Certain information in this document has been excluded pursuant to Regulation S-K, Item (601)(b)(10). Such excluded information is both (i) not material and (ii) the type that the Registrant treats as private or confidential. FIRST AMENDMENT TO CREDIT AGREEMENT AND GUARANTY This FIRST AMENDMENT TO CREDIT AGREEMENT AND GUARANTY (this “Amendment”), dated as of Ma

March 18, 2025 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amend

TABLE OF CONTENTS UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.

February 27, 2025 EX-99.1

Verona Pharma Reports Fourth Quarter and Full Year 2024 Financial Results and Provides Corporate Update OhtuvayreTM (ensifentrine) recorded net product sales of $36.6 million in Q4 and $42.3 million in 2024 More prescriptions filled through February

Verona Pharma Reports Fourth Quarter and Full Year 2024 Financial Results and Provides Corporate Update OhtuvayreTM (ensifentrine) recorded net product sales of $36.

February 27, 2025 EX-19.1

Insider Trading Compliance Policy

VERONA PHARMA PLC (the “Company”) INSIDER TRADING COMPLIANCE POLICY Adopted by the Board of Directors of the Company (“Board of Directors”) on January 1, 2021, as amended by the Board of Directors on February 17, 2023, with effect from February 27, 2023, and as further amended by the Board of Directors on January 17, 2025, with effect from January 17, 2025 This Insider Trading Compliance Policy (t

February 27, 2025 EX-10.19

First Amendment to Revenue Interest Purchase and Sale Agreement, dated as of November 7, 2024 between Verona Pharma, Inc., Verona Pharma plc and Oaktree Fund

[***] Certain information in this document has been excluded pursuant to Regulation S-K, Item 601(b)(10).

February 27, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): February 27, 2025 Verona Pharma p

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): February 27, 2025 Verona Pharma plc (Exact name of registrant as specified in its charter) United Kingdom 001-38067 98-1489389 (State or other jurisdiction of incorporation) (Commissi

February 27, 2025 EX-10.10

, between Verona Pharma plc and Andrew Fisher

March 1, 2024 Andrew Fisher xxxxxxxxxxxxx xxxxxxxxxxxxx Dear Andrew, Verona Pharma (the “Company” or “Verona”) is very pleased to offer you a regular full-time, exempt position.

February 27, 2025 EX-FILING FEES

Filing Fee Table

Calculation of Filing Fee Tables S-8 Verona Pharma plc Table 1: Newly Registered Securities Security Type Security Class Title Fee Calculation Rule Amount Registered Proposed Maximum Offering Price Per Unit Maximum Aggregate Offering Price Fee Rate Amount of Registration Fee 1 Equity Ordinary Shares, nominal value GBP0.

February 27, 2025 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2024 ☐ TRANSITION REPORT PURSUANT TO SECTI

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2024 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 FOR THE TRANSITION PERIOD FROM TO Commission file number: 001-38067 Verona Pharma plc (Exact

February 27, 2025 EX-4.3

Description of Securities

Exhibit 4.3 DESCRIPTION OF SECURITIES DESCRIPTION OF SHARE CAPITAL AND ARTICLES OF ASSOCIATION Set forth below is a summary of certain information concerning the share capital of Verona Pharma plc (the “Company,” “we,” “us,” and “our”) as well as a description of certain provisions of our articles of association and relevant provisions of English law. Because the following is only a summary, it do

February 27, 2025 S-8

As filed with the Securities and Exchange Commission on February 27, 2025

As filed with the Securities and Exchange Commission on February 27, 2025 Registration No.

February 14, 2025 EX-99.1

JOINT FILING AGREEMENT

EX-99.1 2 ex-99-02142025110246.htm JOINT FILING AGREEMENT EXHIBIT 99.1 JOINT FILING AGREEMENT This Joint Filing Agreement, dated as of February 14, 2025, is by and among RA Capital Management, L.P., Peter Kolchinsky, Rajeev Shah, and RA Capital Healthcare Fund, L.P. (the foregoing are collectively referred to herein as the “Filers”). Each of the Filers may be required to file with the United State

January 21, 2025 EX-2

POWER OF ATTORNEY

EXHIBIT 2 POWER OF ATTORNEY KNOW ALL MEN BY THESE PRESENTS, that the undersigned hereby constitutes and appoints Zachary Bambach, Nicole Hatcher and Stephanie Brecher, and each of them, with full power to act without the others, his or her true and lawful attorney-in-fact, with full power of substitution, to sign any and all instruments, certificates and documents that may be necessary, desirable

January 21, 2025 EX-1

AGREEMENT

EXHIBIT 1 AGREEMENT Pursuant to Rule 13d-1(k)(1) under the Securities Exchange Act of 1934, the undersigned hereby agree that only one statement containing the information required by Schedule 13D need be filed with respect to the ownership by each of the undersigned of shares of stock of Verona Pharma plc.

January 7, 2025 EX-99.1

Verona Pharma Reports Strong OhtuvayreTM Launch and Provides Preliminary Fourth Quarter and Full Year 2024 Financial Highlights Approximately $36 million and $42 million net product sales of Ohtuvayre for the fourth quarter and full year 2024, respec

Exhibit 99.1 Verona Pharma Reports Strong OhtuvayreTM Launch and Provides Preliminary Fourth Quarter and Full Year 2024 Financial Highlights Approximately $36 million and $42 million net product sales of Ohtuvayre for the fourth quarter and full year 2024, respectively More than 3,500 unique prescribers and over 16,000 prescriptions filled in 2024 across a broad COPD population Approximately 45% o

January 7, 2025 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): January 7, 2025 Verona Pharma plc

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): January 7, 2025 Verona Pharma plc (Exact name of registrant as specified in its charter) United Kingdom 001-38067 98-1489389 (State or other jurisdiction of incorporation) (Commission

November 14, 2024 EX-99.1

Exhibit 1: Joint Filing Agreement

EX-99.1 2 tm2427451d32ex1.htm EXHIBIT 1 EXHIBIT 1 AGREEMENT This Joint Filing Agreement, dated as of November 14, 2024, is by and among RA Capital Management, L.P., Peter Kolchinsky, Rajeev Shah, and RA Capital Healthcare Fund, L.P. (the foregoing are collectively referred to herein as the “Filers”). Each of the Filers may be required to file with the United States Securities and Exchange Commissi

November 14, 2024 EX-99.B

Power of Attorney

EX-99.B 3 d913111dex99b.htm EX-99.B EXHIBIT B Power of Attorney KNOW ALL MEN BY THESE PRESENTS, that I, Lee S. Ainslie III, hereby make, constitute and appoint Trevor Wiessmann as my agent and attorney-in-fact for the purpose of executing (i) in my personal capacity or (ii) in my capacity as manager or other officer or representative of Maverick Capital Management, LLC, Maverick Capital, Ltd. or a

November 14, 2024 EX-99.A

JOINT FILING AGREEMENT

EX-99.A 2 d913111dex99a.htm EX-99.A EXHIBIT A JOINT FILING AGREEMENT The undersigned hereby agree that the statement on Schedule 13G with respect to the Ordinary Shares of Verona Pharma plc dated as of November 14, 2024, is, and any amendments thereto (including amendments on Schedule 13D) signed by each of the undersigned shall be, filed on behalf of each of us pursuant to and in accordance with

November 14, 2024 SC 13G/A

VRNA / Verona Pharma plc - Depositary Receipt (Common Stock) / PERCEPTIVE ADVISORS LLC - SC 13G/A Passive Investment

SC 13G/A 1 d912088dsc13ga.htm SC 13G/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 13G/A Under the Securities Exchange Act of 1934 (Amendment No. 1)* Verona Pharma plc (Name of Issuer) Ordinary shares, nominal value £0.05 per share (Title of Class of Securities) 925050106** (CUSIP Number) September 30, 2024 (Date of Event Which Requires Filing of this Statement

November 14, 2024 SC 13G/A

VRNA / Verona Pharma plc - Depositary Receipt (Common Stock) / RA CAPITAL MANAGEMENT, L.P. - SC 13G/A Passive Investment

SC 13G/A 1 tm2427451d32sc13ga.htm SC 13G/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 13G/A Under the Securities Exchange Act of 1934 (Amendment No. 4)* Verona Pharma plc (Name of Issuer) Ordinary Shares, nominal value £0.05 per share American Depositary Shares, each representing eight Ordinary Shares (Title of Class of Securities) 925050106 (CUSIP Number) Sep

November 14, 2024 SC 13G

VRNA / Verona Pharma plc - Depositary Receipt (Common Stock) / MAVERICK CAPITAL LTD - SC 13G Passive Investment

SC 13G 1 d913111dsc13g.htm SC 13G UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* Verona Pharma plc (Name of Issuer) Ordinary shares, nominal value £0.05 per share (Title of Class of Securities) 925050106** (CUSIP Number) September 30, 2024 (Date of Event Which Requires Filing of this Statement) Check

November 14, 2024 SC 13G/A

VRNA / Verona Pharma plc - Depositary Receipt (Common Stock) / Deep Track Capital, LP Passive Investment

SC 13G/A 1 deeptrack-vrna093024a1.htm UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 13G/A Under the Securities Exchange Act of 1934 (Amendment No. 1)* Verona Pharma plc (Name of Issuer) Ordinary shares, nominal value £0.05 per share (Title of Class of Securities) 925050106 (CUSIP Number) September 30, 2024 (Date of Event Which Requires Filing of this Statement) Che

November 13, 2024 SC 13G/A

VRNA / Verona Pharma plc - Depositary Receipt (Common Stock) / VIVO VENTURES VII, LLC - AMENDMENT NO. 4 TO SCHEDULE 13G Passive Investment

SC 13G/A 1 ea0221168-13ga4vivo7verona.htm AMENDMENT NO. 4 TO SCHEDULE 13G UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G/A Under the Securities Exchange Act of 1934 (Amendment No. 4) * VERONA PHARMA PLC (Name of Issuer) Ordinary Shares, nominal value £0.05 per share (Title of Class of Securities) 925050106 (CUSIP Number) September 30, 2024 (Date of Event which

November 4, 2024 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): November 4, 2024 Verona Pharma plc (Exact name of registrant as specified in its charter) United Kingdom 001-38067 98-1489389 (State or other jurisdiction of incorporation) (Commissio

November 4, 2024 EX-99.1

Verona Pharma Reports Third Quarter 2024 Financial Results and Provides Corporate Update OhtuvayreTM (ensifentrine) launch recorded Q3 net sales of $5.6 million and October net sales exceeded Q3 Through October more than 2,200 unique prescribers and

Verona Pharma Reports Third Quarter 2024 Financial Results and Provides Corporate Update OhtuvayreTM (ensifentrine) launch recorded Q3 net sales of $5.

November 4, 2024 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2024 ☐ TRANSITION REPORT PURSUANT

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2024 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 FOR THE TRANSITION PERIOD FROM TO Commission File Number: 001-38067 Verona Pharma pl

August 28, 2024 SC 13D/A

VRNA / Verona Pharma plc - Depositary Receipt (Common Stock) / Growth Equity Opportunities Fund IV, LLC - GROWTH EQUITY OPPORTUNITIES FUND IV, LLC / VERONA PHARMA PLC -- SCHEDULE 13DA (#3) Activist Investment

Schedule 13D UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D Under the Securities Exchange Act of 1934 (Amendment No. 3)* Verona Pharma plc (Name of Issuer) Ordinary Shares, nominal value £0.05 (represented by American Depositary Shares) (Title of Class of Securities) 925050106 (CUSIP Number) Stephanie Brecher New Enterprise Associates 1954 Greenspring Drive, S

August 8, 2024 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): August 8, 2024 Verona Pharma plc (Exact name of registrant as specified in its charter) United Kingdom 001-38067 98-1489389 (State or other jurisdiction of incorporation) (Commission

August 8, 2024 EX-99.1

Verona Pharma Reports Second Quarter 2024 Financial Results and Provides Corporate Update OhtuvayreTM (ensifentrine) now available; patient shipments started Strong balance sheet supports commercialization and pipeline expansion Conference call today

Verona Pharma Reports Second Quarter 2024 Financial Results and Provides Corporate Update OhtuvayreTM (ensifentrine) now available; patient shipments started Strong balance sheet supports commercialization and pipeline expansion Conference call today at 9:00 a.

August 8, 2024 EX-10.1

Revenue Interest Purchase and Sale Agreement, dated as of May 9, 2024, between Verona Pharma, Inc., Verona Pharma plc and Oaktree Fund Administration, LLC, as the administrative agent and the other purchasers party thereto

[***] Certain information in this document has been excluded pursuant to Regulation S-K, Item (601)(b)(10).

August 8, 2024 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2024 ☐ TRANSITION REPORT PURSUANT TO S

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2024 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 FOR THE TRANSITION PERIOD FROM TO Commission File Number: 001-38067 Verona Pharma plc (Ex

July 29, 2024 EX-99.1

AGREEMENT

EX-99.1 2 d862146dex991.htm EX-99.1 EXHIBIT 1 AGREEMENT The persons below hereby agree that the Schedule 13G to which this agreement is attached as an exhibit, as well as all future amendments to such Schedule 13G, shall be filed on behalf of each of them. This agreement is intended to satisfy the requirements of Rule 13d-1(k)(1)(iii) under the Securities Exchange Act of 1934. Date: July 29, 2024

July 29, 2024 SC 13G

VRNA / Verona Pharma plc - Depositary Receipt (Common Stock) / PERCEPTIVE ADVISORS LLC - SC 13G Passive Investment

SC 13G 1 d862146dsc13g.htm SC 13G UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* Verona Pharma plc (Name of Issuer) Ordinary shares, nominal value £0.05 per share (Title of Class of Securities) 925050106** (CUSIP Number) July 17, 2024 (Date of Event Which Requires Filing of this Statement) Check the a

July 12, 2024 SC 13G

VRNA / Verona Pharma plc - Depositary Receipt (Common Stock) / Deep Track Capital, LP Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No.

June 27, 2024 EX-99.1

Verona Pharma Announces US FDA Approval of OhtuvayreTM (ensifentrine) Ohtuvayre is indicated for the maintenance treatment of COPD allowing for broad use in COPD patients First inhaled COPD treatment providing bronchodilation and non-steroidal anti-i

Exhibit 99.1 Verona Pharma Announces US FDA Approval of OhtuvayreTM (ensifentrine) Ohtuvayre is indicated for the maintenance treatment of COPD allowing for broad use in COPD patients First inhaled COPD treatment providing bronchodilation and non-steroidal anti-inflammatory effects Conference call tomorrow at 8:30 a.m. EDT / 1:30 p.m. BST LONDON and RALEIGH, N.C., June 26, 2024 – Verona Pharma plc

June 27, 2024 8-K

Regulation FD Disclosure, Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): June 26, 2024 Verona Pharma plc (Exact name of registrant as specified in its charter) United Kingdom 001-38067 98-1489389 (State or other jurisdiction of incorporation) (Commission F

May 10, 2024 EX-10.2

redit Agreement and Guaranty, dated as of May 9, 2024, by and among Verona

[***] Certain information in this document has been excluded pursuant to Regulation S-K, Item (601)(b)(10).

May 10, 2024 EX-10.1

dated as of May 9, 2024, between Verona Pharma

[***] Certain information in this document has been excluded pursuant to Regulation S-K, Item (601)(b)(10).

May 10, 2024 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2024 ☐ TRANSITION REPORT PURSUANT TO

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2024 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 FOR THE TRANSITION PERIOD FROM TO Commission File Number: 001-38067 Verona Pharma plc (E

May 10, 2024 S-8

As filed with the Securities and Exchange Commission on May 9, 2024

As filed with the Securities and Exchange Commission on May 9, 2024 Registration No.

May 10, 2024 EX-FILING FEES

Filing Fee Table

Exhibit 107.1 CALCULATION OF FILING FEE TABLE FORM S-8 (Form Type) Verona Pharma plc (Exact Name of Registrant as Specified in its Charter) Table 1: Newly Registered Securities Security Type Security Class Title Fee Calculation Rule Amount to be Registered (1) Proposed Maximum Offering Price Per Unit Maximum Aggregate Offering Price Fee Rate Amount of Registration Fee Equity Ordinary Shares, nomin

May 9, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): May 9, 2024 Verona Pharma plc (Ex

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): May 9, 2024 Verona Pharma plc (Exact name of registrant as specified in its charter) United Kingdom 001-38067 98-1489389 (State or other jurisdiction of incorporation) (Commission Fil

May 9, 2024 EX-99.1

Verona Pharma Reports First Quarter 2024 Financial Results and Provides Corporate Update PDUFA Target Action Date for Ensifentrine of June 26, 2024 Finalizing commercial launch preparations Strong balance sheet supports commercialization and pipeline

Verona Pharma Reports First Quarter 2024 Financial Results and Provides Corporate Update PDUFA Target Action Date for Ensifentrine of June 26, 2024 Finalizing commercial launch preparations Strong balance sheet supports commercialization and pipeline expansion Conference call today at 9:00 a.

May 9, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): May 9, 2024 Verona Pharma plc (Ex

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): May 9, 2024 Verona Pharma plc (Exact name of registrant as specified in its charter) United Kingdom 001-38067 98-1489389 (State or other jurisdiction of incorporation) (Commission Fil

May 9, 2024 EX-99.1

Verona Pharma Announces $650 Million Strategic Financing with Oaktree and OMERS Non-dilutive funding will support planned US commercial launch and expansion of ensifentrine’s clinical activities Cash runway extended beyond 2026

Exhibit 99.1 Verona Pharma Announces $650 Million Strategic Financing with Oaktree and OMERS Non-dilutive funding will support planned US commercial launch and expansion of ensifentrine’s clinical activities Cash runway extended beyond 2026 LONDON and RALEIGH, N.C., May 9, 2024 – Verona Pharma plc (Nasdaq: VRNA) (“Verona Pharma”), announces it and its wholly-owned subsidiary, Verona Pharma, Inc. (

April 30, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): April 26, 2024 Verona Pharma plc

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): April 26, 2024 Verona Pharma plc (Exact name of registrant as specified in its charter) United Kingdom 001-38067 98-1489389 (State or other jurisdiction of incorporation) (Commission

March 20, 2024 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amend

TABLE OF CONTENTS UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.

March 8, 2024 PRE 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amend

TABLE OF CONTENTS UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.

February 29, 2024 EX-10.23

cial Supply Agreement between

[***] Certain information in this document has been excluded pursuant to Regulation S-K, Item (601)(b)(10).

February 29, 2024 10-K

December 31,

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2023 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 FOR THE TRANSITION PERIOD FROM TO Commission File Number: 001-38067 Verona Pharma plc (Exact

February 29, 2024 EX-99.1

Verona Pharma Reports Fourth Quarter and Full Year 2023 Financial Results and Provides Corporate Update PDUFA Target Action Date for ensifentrine of June 26, 2024 Commercialization preparations advance Strong balance sheet supports commercialization

Verona Pharma Reports Fourth Quarter and Full Year 2023 Financial Results and Provides Corporate Update PDUFA Target Action Date for ensifentrine of June 26, 2024 Commercialization preparations advance Strong balance sheet supports commercialization and Company's growth Conference call today at 9:00 a.

February 29, 2024 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): February 29, 2024 Verona Pharma plc (Exact name of registrant as specified in its charter) United Kingdom 001-38067 98-1489389 (State or other jurisdiction of incorporation) (Commissi

February 29, 2024 EX-4.5

Description of Securities

DESCRIPTION OF SECURITIES DESCRIPTION OF SHARE CAPITAL AND ARTICLES OF ASSOCIATION Set forth below is a summary of certain information concerning the share capital of Verona Pharma plc (the “Company,” “we,” “us,” and “our”) as well as a description of certain provisions of our articles of association and relevant provisions of English law.

February 29, 2024 EX-97.#

Policy for Recovery of Erroneously Awarded Compensation

1 Verona Pharma plc Clawback PolicyUS-DOCS\141846929.5 VERONA PHARMA PLC POLICY FOR RECOVERY OF ERRONEOUSLY AWARDED COMPENSATION Adopted by the Verona Pharma plc Board of Directors on October 12, 2023, effective October 2, 2023 Verona Pharma plc (the “Company”) has adopted this Policy for Recovery of Erroneously Awarded Compensation (the “Policy”), effective as of October 2, 2023 (the “Effective D

February 29, 2024 EX-21.1

List of Subsidiaries of Verona Pharma plc

Exhibit 21.1 SUBSIDIARIES OF VERONA PHARMA PLC Legal Name of Subsidiary Jurisdiction of Organization Verona Pharma, Inc. Delaware

February 14, 2024 EX-99.1

Exhibit 1: Joint Filing Agreement

EX-99.1 2 tm246065d22ex1.htm EXHIBIT 1 EXHIBIT 1 AGREEMENT This Joint Filing Agreement, dated as of February 14, 2024, is by and among RA Capital Management, L.P., Peter Kolchinsky, Rajeev Shah, and RA Capital Healthcare Fund, L.P. (the foregoing are collectively referred to herein as the “Filers”). Each of the Filers may be required to file with the United States Securities and Exchange Commissio

February 14, 2024 EX-99.1

AGREEMENT

EX-99.1 2 d635584dex991.htm EX-99.1 EXHIBIT 1 AGREEMENT The persons below hereby agree that the Schedule 13G to which this agreement is attached as an exhibit, as well as all future amendments to such Schedule 13G, shall be filed on behalf of each of them. This agreement is intended to satisfy the requirements of Rule 13d-1(k)(1)(iii) under the Securities Exchange Act of 1934. Date: February 14, 2

February 14, 2024 SC 13G/A

VRNA / Verona Pharma plc - Depositary Receipt (Common Stock) / PERCEPTIVE ADVISORS LLC - SC 13G/A Passive Investment

SC 13G/A 1 d635584dsc13ga.htm SC 13G/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 13G/A Under the Securities Exchange Act of 1934 (Amendment No. 1)* Verona Pharma plc (Name of Issuer) Ordinary shares, nominal value £0.05 per share (Title of Class of Securities) 925050106** (CUSIP Number) December 31, 2023 (Date of Event Which Requires Filing of this Statement)

February 14, 2024 SC 13G/A

VRNA / Verona Pharma plc - Depositary Receipt (Common Stock) / RA CAPITAL MANAGEMENT, L.P. - SC 13G/A Passive Investment

SC 13G/A 1 tm246065d22sc13ga.htm SC 13G/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 13G/A Under the Securities Exchange Act of 1934 (Amendment No. 3)* Verona Pharma plc (Name of Issuer) Ordinary Shares, nominal value £0.05 per share American Depositary Shares, each representing eight Ordinary Shares (Title of Class of Securities) 925050106 (CUSIP Number) Dece

February 8, 2024 SC 13G

VRNA / Verona Pharma plc - Depositary Receipt (Common Stock) / WELLINGTON MANAGEMENT GROUP LLP - SEC SCHEDULE 13G Passive Investment

SC 13G 1 SEC13GFiling.htm SEC SCHEDULE 13G UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* Verona Pharma plc (Name of Issuer) Common Stock (Title of Class of Securities) G9337X139 (CUSIP Number) December 29, 2023 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to desig

February 2, 2024 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): January 31, 2024 Verona Pharma plc (Exact name of registrant as specified in its charter) United Kingdom 001-39067 98-1489389 (State or other jurisdiction of incorporation) (Commissio

January 2, 2024 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): December 27, 2023 Verona Pharma p

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): December 27, 2023 Verona Pharma plc (Exact name of registrant as specified in its charter) United Kingdom 001-38067 98-1489389 (State or other jurisdiction of incorporation) (Commissi

January 2, 2024 EX-10.1

Loan and Security Agreement, dated as of December 27, 2023, by and among Verona Pharma, Inc., Oxford Finance LLC, as collateral agent and as a lender, and the other lenders party thereto

Exhibit 10.1 CERTAIN CONFIDENTIAL INFORMATION CONTAINED IN THIS DOCUMENT, MARKED BY [***], HAS BEEN OMITTED FROM THIS EXHIBIT BECAUSE IT IS BOTH (I) NOT MATERIAL AND (II) THE TYPE OF INFORMATION THAT THE REGISTRANT TREATS AS PRIVATE OR CONFIDENTIAL LOAN AND SECURITY AGREEMENT THIS LOAN AND SECURITY AGREEMENT (as the same may from time to time be amended, restated, amended and restated, supplemente

January 2, 2024 EX-99.1

Verona Pharma enters into Debt Facility of up to $400 Million with Oxford Finance and Hercules Capital Strengthens financial flexibility to support the Company’s continued growth

Exhibit 99.1 Verona Pharma enters into Debt Facility of up to $400 Million with Oxford Finance and Hercules Capital Strengthens financial flexibility to support the Company’s continued growth LONDON and RALEIGH, N.C., January 2, 2024 – Verona Pharma plc (Nasdaq: VRNA) (“Verona Pharma”), announces it and its wholly-owned subsidiary, Verona Pharma, Inc. (the “Company”), have entered into a debt fina

December 18, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): December 14, 2023 Verona Pharma p

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): December 14, 2023 Verona Pharma plc (Exact name of registrant as specified in its charter) United Kingdom 001-38067 98-1489389 (State or other jurisdiction of incorporation) (Commissi

December 18, 2023 EX-16.1

Letter of PricewaterhouseCoopers LLP, dated December 14, 2023.

Exhibit 16.1 December 14, 2023 Securities and Exchange Commission 100 F Street, N.E. Washington, DC 20549 Commissioners: We have read the statements made by Verona Pharma plc pursuant to Item 4.01 of Form 8-K (copy attached), which we understand will be filed with the Securities and Exchange Commission as part of the Current Report on Form 8-K of Verona Pharma plc dated December 14, 2023. We agree

November 2, 2023 EX-99.1

Verona Pharma Reports Third Quarter 2023 Financial Results and Provides Corporate Update US FDA accepted NDA filing for ensifentrine for maintenance treatment of COPD PDUFA Target Action Date of June 26, 2024 Commercial launch preparations supported

Verona Pharma Reports Third Quarter 2023 Financial Results and Provides Corporate Update US FDA accepted NDA filing for ensifentrine for maintenance treatment of COPD PDUFA Target Action Date of June 26, 2024 Commercial launch preparations supported by strong balance sheet Conference call today at 9:00 a.

November 2, 2023 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): November 2, 2023 Verona Pharma plc (Exact name of registrant as specified in its charter) United Kingdom 001-38067 98-1489389 (State or other jurisdiction of incorporation) (Commissio

November 2, 2023 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2023 ☐ TRANSITION REPORT PURSUANT

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2023 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 FOR THE TRANSITION PERIOD FROM TO Commission File Number: 001-38067 Verona Pharma pl

September 11, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): September 11, 2023 Verona Pharma

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): September 11, 2023 Verona Pharma plc (Exact name of registrant as specified in its charter) United Kingdom 001-38067 98-1489389 (State or other jurisdiction of incorporation) (Commiss

September 1, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): August 28, 2023 Verona Pharma plc

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): August 28, 2023 Verona Pharma plc (Exact name of registrant as specified in its charter) United Kingdom 001-39067 98-1489389 (State or other jurisdiction of incorporation) (Commission

September 1, 2023 EX-10.1

Agreement of Sublease, dated August 28, 2023, by and between Verona Pharma, Inc. and insightsoftware, LLC

Exhibit 10.1 THIS AGREEMENT OF SUBLEASE (“Sublease”) made as of the 28th day of August, 2023, by and between insightsoftware, LLC (“Sublandlord”) and Verona Pharma, Inc. (“Subtenant”). WITNESSETH: WHEREAS, Sublandlord has leased the Premises (as hereinafter defined) from Highwoods Realty Limited Partnership (as successor in interest to Highwoods-DLF Forum, LLC) (the “Landlord”) pursuant to a certa

August 3, 2023 EX-99.1

Verona Pharma Reports Second Quarter 2023 Financial Results and Provides Corporate Update NDA submitted to US FDA for ensifentrine for maintenance treatment of COPD Phase 3 ENHANCE data published in the American Journal of Respiratory and Critical Ca

Verona Pharma Reports Second Quarter 2023 Financial Results and Provides Corporate Update NDA submitted to US FDA for ensifentrine for maintenance treatment of COPD Phase 3 ENHANCE data published in the American Journal of Respiratory and Critical Care Medicine Strong balance sheet to support commercial launch preparations Conference call today at 9:00 a.

August 3, 2023 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): August 3, 2023 Verona Pharma plc (Exact name of registrant as specified in its charter) United Kingdom 001-39067 98-1489389 (State or other jurisdiction of incorporation) (Commission

August 3, 2023 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2023 ☐ TRANSITION REPORT PURSUANT TO S

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2023 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 FOR THE TRANSITION PERIOD FROM TO Commission File Number: 001-38067 Verona Pharma plc (Ex

May 16, 2023 SC 13D/A

VRNA / Verona Pharma Plc - ADR / ORBIMED ADVISORS LLC - AMENDMENT NO. 4 Activist Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D Under the Securities Exchange Act of 1934 (Amendment No. 4)* Verona Pharma plc (Name of Issuer) Ordinary Shares (Title of Class of Securities) 925050106 (CUSIP Number) OrbiMed Advisors LLC OrbiMed Capital GP VI LLC 601 Lexington Avenue, 54th Floor New York, NY 10022 Telephone: (212) 739-6400 (Name, Address and Tel

May 16, 2023 EX-99.1

JOINT FILING AGREEMENT

Exhibit 1 JOINT FILING AGREEMENT The undersigned hereby agree that the Amendment No.

May 9, 2023 S-8

As filed with the Securities and Exchange Commission on May 9, 2023

As filed with the Securities and Exchange Commission on May 9, 2023 Registration No.

May 9, 2023 EX-FILING FEES

Filing Fee Table

Exhibit 107.1 CALCULATION OF FILING FEE TABLE FORM S-8 (Form Type) Verona Pharma plc (Exact Name of Registrant as Specified in its Charter) Table 1: Newly Registered Securities Security Type Security Class Title Fee Calculation Rule Amount to be Registered (1) Proposed Maximum Offering Price Per Unit Maximum Aggregate Offering Price Fee Rate Amount of Registration Fee Equity Ordinary Shares, nomin

May 9, 2023 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2023 ☐ TRANSITION REPORT PURSUANT TO

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2023 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 FOR THE TRANSITION PERIOD FROM TO Commission File Number: 001-38067 Verona Pharma plc (E

May 9, 2023 EX-99.1

Verona Pharma Reports First Quarter 2023 Financial Results and Provides Corporate Update NDA submission on schedule for Q2 2023 12 abstracts and one symposium expanding on successful Phase 3 ENHANCE data to be presented at American Thoracic Society 2

Verona Pharma Reports First Quarter 2023 Financial Results and Provides Corporate Update NDA submission on schedule for Q2 2023 12 abstracts and one symposium expanding on successful Phase 3 ENHANCE data to be presented at American Thoracic Society 2023 Strong balance sheet to support commercial launch preparations Conference call today at 9:00 a.

May 9, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): May 9, 2023 Verona Pharma plc (Ex

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): May 9, 2023 Verona Pharma plc (Exact name of registrant as specified in its charter) United Kingdom 001-39067 98-1489389 (State or other jurisdiction of incorporation) (Commission Fil

May 1, 2023 EX-10.1

Verona Pharma plc Second Amended and Restated 2017 Incentive Award Plan

Exhibit 10.1 VERONA PHARMA PLC SECOND AMENDED AND RESTATED 2017 INCENTIVE AWARD PLAN (As amended and restated effective March 14, 2023) ARTICLE I. PURPOSE The Plan’s purpose is to enhance the Company’s ability to attract, retain and motivate persons who make (or are expected to make) important contributions to the Company by providing these individuals with equity ownership opportunities. Capitali

May 1, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): April 27, 2023 Verona Pharma plc

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): April 27, 2023 Verona Pharma plc (Exact name of registrant as specified in its charter) United Kingdom 001-38067 98-1489389 (State or other jurisdiction of incorporation) (Commission

April 25, 2023 SC 13G/A

VRNA / Verona Pharma Plc - ADR / Access Industries Holdings LLC - SC 13G/A Passive Investment

SC 13G/A SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 3)* Verona Pharma plc (Name of Issuer) Ordinary shares, nominal value £0.05 per share (Title of Class of Securities) 925050106** (CUSIP Number) April 18, 2023 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule

April 25, 2023 EX-99.1

JOINT FILING AGREEMENT

EX-99.1 Exhibit 99.1 JOINT FILING AGREEMENT Pursuant to Rule 13d-1(k)(1) promulgated under the Securities Exchange Act of 1934, as amended, the undersigned agree that the Statement on Schedule 13G to which this Exhibit is attached is filed on behalf of each of them. Each of them is individually eligible to use the Schedule 13G to which this Exhibit is attached. Each of them is responsible for the

April 20, 2023 EX-99.1

AGREEMENT

EX-99.1 EXHIBIT 1 AGREEMENT The persons below hereby agree that the Schedule 13G to which this agreement is attached as an exhibit, as well as all future amendments to such Schedule 13G, shall be filed on behalf of each of them. This agreement is intended to satisfy the requirements of Rule 13d-1(k)(1)(iii) under the Securities Exchange Act of 1934. Date: April 20, 2023 PERCEPTIVE ADVISORS LLC By:

April 20, 2023 SC 13G

VRNA / Verona Pharma Plc - ADR / PERCEPTIVE ADVISORS LLC - SC 13G Passive Investment

SC 13G UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* Verona Pharma plc (Name of Issuer) Ordinary shares, nominal value £0.05 per share (Title of Class of Securities) 925050106** (CUSIP Number) April 18, 2023 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designat

March 21, 2023 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amend

TABLE OF CONTENTS UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.

March 7, 2023 EX-99.(D)

Exhibit (d)

Exhibit (d) March 7, 2023 Citibank, N.A. – ADR Department 388 Greenwich Street New York, New York 10013 Ladies and Gentlemen: We refer to the Registration Statement on Form F-6 (the “Registration Statement”) to be filed with the Securities and Exchange Commission (the “SEC”) by the legal entity created by the Deposit Agreement (as hereinafter defined) for the purpose of registering under the Unite

March 7, 2023 EX-4.4

Form of Indenture.

Exhibit 4.4 Verona Pharma plc INDENTURE Dated as of , 20 [] Trustee TABLE OF CONTENTS Page ARTICLE I. DEFINITIONS AND INCORPORATION BY REFERENCE 1 Section 1.1. Definitions 1 Section 1.2. Other Definitions 4 Section 1.3. Incorporation by Reference of Trust Indenture Act 5 Section 1.4. Rules of Construction 5 ARTICLE II. THE SECURITIES 5 Section 2.1. Issuable in Series 5 Section 2.2. Establishment o

March 7, 2023 EX-21.1

List of Subsidiaries of Verona Pharma plc

Exhibit 21.1 SUBSIDIARIES OF VERONA PHARMA PLC Legal Name of Subsidiary Jurisdiction of Organization Verona Pharma, Inc. Delaware

March 7, 2023 EX-99.(B)(III)

VERONA PHARMA PLC

EX-99.(B)(III) 5 e618333ex99-biii.htm Exhibit (b)(iii) VERONA PHARMA PLC May 12, 2021 Citibank, N.A. – ADR Department 388 Greenwich Street New York, NY 10013 Attn: Ryan Everett Program ADSs (CUSIP No.: 925050106) Ladies and Gentlemen: Reference is made to the Deposit Agreement, dated as of May 2, 2017, as amended and supplemented from time to time (the “Deposit Agreement”), by and among Verona Pha

March 7, 2023 EX-99.(B)(II)

Verona Pharma plc

Exhibit (b)(ii) Verona Pharma plc As of October 19, 2020 Citibank, N.A. - ADR Department 388 Greenwich Street New York, New York 10013 Re: Restricted ADSs (CUSIP No.: 925050981) Ladies and Gentlemen: Reference is made to the Deposit Agreement, dated as of dated as of May 2, 2017, as amended and supplemented from time to time (the “Deposit Agreement”), by and among Verona Pharma plc, a public limit

March 7, 2023 EX-99.(E)

Rule 466 Certification

Exhibit (e) Rule 466 Certification The depositary, Citibank, N.A., represents and certifies the following: (i) That it had previously filed a registration statement on Form F-6 (Registration No. 333-217353) with respect to Verona Pharma plc, which the U.S. Securities and Exchange Commission declared effective, with terms of deposit identical to the terms of deposit of this Form F-6 Registration St

March 7, 2023 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2022 ☐ TRANSITION REPORT PURSUANT TO SECTI

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2022 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 FOR THE TRANSITION PERIOD FROM TO Commission File Number: 001-38067 Verona Pharma plc (Exact

March 7, 2023 S-3ASR

As filed with the Securities and Exchange Commission on March 7, 2023

TABLE OF CONTENTS As filed with the Securities and Exchange Commission on March 7, 2023 Registration No.

March 7, 2023 EX-99.(A)

DEPOSIT AGREEMENT by and among Verona Pharma plc CITIBANK, N.A., as Depositary, ALL HOLDERS AND BENEFICIAL OWNERS OF AMERICAN DEPOSITARY SHARES ISSUED HEREUNDER Dated as of May 2, 2017 TABLE OF CONTENTS

Exhibit (a) DEPOSIT AGREEMENT by and among Verona Pharma plc and CITIBANK, N.A., as Depositary, and ALL HOLDERS AND BENEFICIAL OWNERS OF AMERICAN DEPOSITARY SHARES ISSUED HEREUNDER Dated as of May 2, 2017 TABLE OF CONTENTS ARTICLE I DEFINITIONS 1 Section 1.1 “ADS Record Date” 1 Section 1.2 “Affiliate” 1 Section 1.3 “American Depositary Receipt(s)”, “ADR(s)” and “Receipt(s)” 1 Section 1.4 “American

March 7, 2023 F-6EF

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM F-6 REGISTRATION STATEMENT THE SECURITIES ACT OF 1933 FOR AMERICAN DEPOSITARY SHARES EVIDENCED BY AMERICAN DEPOSITARY RECEIPTS Verona Pharma plc (Exact name of issuer of deposited securit

As filed with the Securities and Exchange Commission on March 7, 2023 Registration No.

March 7, 2023 EX-1.2

, dated as of March 19, 2021, between Verona Pharma plc and Jefferies LLC, and as amended.

EXHIBIT 1.2 OPEN MARKET SALE AGREEMENT March 19, 2021 JEFFERIES LLC 520 Madison Avenue New York, New York 10022 Ladies and Gentlemen: Verona Pharma plc, a public limited company incorporated under the laws of England and Wales with registered number 5375156 (the “Company”), proposes, subject to the terms and conditions stated herein, to issue and sell from time to time through Jefferies LLC, as sa

March 7, 2023 EX-99.1

Verona Pharma Reports Fourth Quarter and Full Year 2022 Financial Results and Provides Corporate Update Transformational results in Phase 3 ENHANCE program for COPD NDA submission expected Q2 2023 Strong balance sheet to support planned US commercial

Verona Pharma Reports Fourth Quarter and Full Year 2022 Financial Results and Provides Corporate Update Transformational results in Phase 3 ENHANCE program for COPD NDA submission expected Q2 2023 Strong balance sheet to support planned US commercial launch Conference call today at 9:00 a.

March 7, 2023 EX-FILING FEES

Filing Fee Table.

Exhibit 107 Calculation of Filing Fee Table Form S-3 (Form Type) Verona Pharma plc (Exact Name of Registrant as Specified in its Charter) Table 1: Newly Registered and Carry Forward Securities Security Type Security Class Title Fee Calculation or Carry Forward Rule Amount Registered Proposed Maximum Offering Price per Unit Maximum Aggregate Offering Price Fee Rate Amount of Registration Fee Carry Forward Form Type Carry Forward File Number Carry Forward Initial effective date Filing Fee Previously Paid In Connection With Unheld Securities to be Carried Forward Newly Registered Securities Fees to be Paid Equity Ordinary Shares, nominal value £0.

March 7, 2023 EX-99.(B)(I)

VERONA PHARMA PLC

Exhibit (b)(i) VERONA PHARMA PLC As of July 22, 2020 Citibank, N.A. - ADR Department 388 Greenwich Street New York, New York 10013 Attention: Ryan Everett Re: PIPE and Restricted ADS Letter Agreement Ladies and Gentlemen: We refer to the Deposit Agreement, dated as of May 2, 2017 (the “Deposit Agreement”), by and among Verona Pharma plc, a public limited company incorporated under the laws of Engl

March 7, 2023 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): March 7, 2023 Verona Pharma plc (

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): March 7, 2023 Verona Pharma plc (Exact name of registrant as specified in its charter) United Kingdom 001-39067 98-1489389 (State or other jurisdiction of incorporation) (Commission F

February 14, 2023 SC 13G/A

VRNA / Verona Pharma plc / RA CAPITAL MANAGEMENT, L.P. - SC 13G/A Passive Investment

SC 13G/A 1 tm236221d25sc13ga.htm SC 13G/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 13G/A Under the Securities Exchange Act of 1934 (Amendment No. 2)* Verona Pharma plc (Name of Issuer) Ordinary Shares, nominal value £0.05 per share American Depositary Shares, each representing eight Ordinary Shares (Title of Class of Securities) 925050106 (CUSIP Number) Dece

February 14, 2023 SC 13G/A

VRNA / Verona Pharma plc / VIVO VENTURES VII, LLC - AMENDMENT NO. 3 TO SCHEDULE 13G Passive Investment

SC 13G/A 1 ea173391-13ga3vivo7verona.htm AMENDMENT NO. 3 TO SCHEDULE 13G UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G/A Under the Securities Exchange Act of 1934 (Amendment No. 3) * VERONA PHARMA PLC (Name of Issuer) Ordinary Shares, nominal value £0.05 per share (Title of Class of Securities) 925050106 (CUSIP Number) December 31, 2022 (Date of Event which R

February 9, 2023 SC 13G/A

VRNA / Verona Pharma plc / Access Industries Holdings LLC - SC 13G/A Passive Investment

SC 13G/A 1 d459827dsc13ga.htm SC 13G/A SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 2)* Verona Pharma plc (Name of Issuer) Ordinary shares, nominal value £0.05 per share (Title of Class of Securities) 925050106** (CUSIP Number) February 8, 2023 (Date of Event Which Requires Filing of this Statement) Check the approp

February 9, 2023 EX-99.1

JOINT FILING AGREEMENT

EX-99.1 2 d459827dex991.htm EX-99.1 Exhibit 99.1 JOINT FILING AGREEMENT Pursuant to Rule 13d-1(k)(1) promulgated under the Securities Exchange Act of 1934, as amended, the undersigned agree that the Statement on Schedule 13G to which this Exhibit is attached is filed on behalf of each of them. Each of them is individually eligible to use the Schedule 13G to which this Exhibit is attached. Each of

February 6, 2023 SC 13G/A

VRNA / Verona Pharma plc / WELLINGTON MANAGEMENT GROUP LLP - SEC SCHEDULE 13G Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 1 )* Verona Pharma PLC (Name of Issuer) Common Stock (Title of Class of Securities) 925050106 (CUSIP Number) December 30, 2022 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which this Sche

December 27, 2022 EX-99.1

JOINT FILING AGREEMENT

Exhibit 1 JOINT FILING AGREEMENT The undersigned hereby agree that the Amendment No.

December 27, 2022 SC 13D/A

VRNA / Verona Pharma plc / ORBIMED ADVISORS LLC - AMENDMENT NO. 3 Activist Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D Under the Securities Exchange Act of 1934 (Amendment No. 3)* Verona Pharma plc (Name of Issuer) Ordinary Shares (Title of Class of Securities) 925050106 (CUSIP Number) OrbiMed Advisors LLC OrbiMed Capital GP VI LLC OrbiMed Capital LLC 601 Lexington Avenue, 54th Floor New York, NY 10022 Telephone: (212) 739-6400 (N

December 20, 2022 EX-99.1

ENHANCE - 1 Phase 3 data December 2022 Nasdaq: VRNA | www.veronapharma.com Forward - looking statements This presentation contains “forward‐looking” statements that are based on the beliefs and assumptions and on information currently available to ma

Exhibit 99.1 ENHANCE - 1 Phase 3 data December 2022 Nasdaq: VRNA | www.veronapharma.com Forward - looking statements This presentation contains “forward‐looking” statements that are based on the beliefs and assumptions and on information currently available to management of Verona Pharma plc (together with its consolidated subsidiary, the “Company”) .. All statements other than statements of histo

December 20, 2022 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): December 20, 2022 Verona Pharma p

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): December 20, 2022 Verona Pharma plc (Exact name of registrant as specified in its charter) United Kingdom 001-39067 98-1489389 (State or other jurisdiction of incorporation) (Commissi

November 15, 2022 EX-FILING FEES

Filing Fee Table

Exhibit 107.1 Calculation of Filing Fee Tables Form S-8 (Form Type) Verona Pharma plc (Exact Name of Registrant as Specified in its Charter) Table 1—Newly Registered Securities Security Type Security Class Title Fee Calculation Rule Amount to be Registered (1) Proposed Maximum Offering Price Per Unit Maximum Aggregate Offering Price Fee Rate Amount of Registration Fee Equity Ordinary Shares, nomin

November 15, 2022 S-8

As filed with the Securities and Exchange Commission on November 15, 2022

As filed with the Securities and Exchange Commission on November 15, 2022 Registration No.

November 9, 2022 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): November 9, 2022 Verona Pharma pl

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): November 9, 2022 Verona Pharma plc (Exact name of registrant as specified in its charter) United Kingdom 001-39067 98-1489389 (State or other jurisdiction of incorporation) (Commissio

November 9, 2022 EX-99.1

Verona Pharma Reports Third Quarter 2022 Financial Results and Provides Corporate Update Access to up to $400 million expected to provide cash runway through at least 2025 Top-line Phase 3 ENHANCE-1 data expected around the end of 2022 Conference cal

Verona Pharma Reports Third Quarter 2022 Financial Results and Provides Corporate Update Access to up to $400 million expected to provide cash runway through at least 2025 Top-line Phase 3 ENHANCE-1 data expected around the end of 2022 Conference call today at 9:00 a.

November 9, 2022 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2022 ☐ TRANSITION REPORT PURSUANT

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2022 OR ☐ TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 FOR THE TRANSITION PERIOD FROM TO Commission File Number: 001-38067 Verona Pharma pl

October 17, 2022 8-K

Entry into a Material Definitive Agreement, Termination of a Material Definitive Agreement, Creation of a Direct Financial Obligation or an Obligation under an Off-Balance Sheet Arrangement of a Registrant

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): October 14, 2022 Verona Pharma plc (Exact name of registrant as specified in its charter) United Kingdom 001-38067 98-1489389 (State or other jurisdiction of incorporation) (Commissio

October 17, 2022 EX-10.1

Loan and Security Agreement, dated as of October 14, 2022, by and among Verona Pharma plc, Verona Pharma, Inc., Oxford Finance Luxembourg S.À R.L., as collateral agent and as a lender, and the other lenders party thereto

Exhibit 10.1 LOAN AND SECURITY AGREEMENT THIS LOAN AND SECURITY AGREEMENT (as the same may from time to time be amended, restated, amended and restated, supplemented or otherwise modified, this ?Agreement?) dated as of October 14, 2022 (the ?Effective Date?) among OXFORD FINANCE LUXEMBOURG S.? R.L., a Luxembourg private limited liability company (soci?t? ? responsabilit? limit?e) with registered o

September 7, 2022 SC 13D/A

VRNA / Verona Pharma plc / Growth Equity Opportunities Fund IV, LLC - GROWTH EQUITY OPPORTUNITIES FUND IV, LLC / VERONA PHARMA PLC -- SCHEDULE 13DA (#2) Activist Investment

Schedule 13D UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D Under the Securities Exchange Act of 1934 (Amendment No. 2)* Verona Pharma plc (Name of Issuer) Ordinary Shares, nominal value £0.05 (represented by American Depositary Shares) (Title of Class of Securities) 925050106 (CUSIP Number) Louis S. Citron, Esq. New Enterprise Associates 1954 Greenspring Driv

August 12, 2022 EX-99.1

JOINT FILING AGREEMENT

Exhibit 1 JOINT FILING AGREEMENT The undersigned hereby agree that the Amendment No.

August 12, 2022 SC 13D/A

VRNA / Verona Pharma plc / ORBIMED ADVISORS LLC - AMENDMENT NO. 2 Activist Investment

SC 13D/A 1 ss1244824sc13da.htm AMENDMENT NO. 2 UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D Under the Securities Exchange Act of 1934 (Amendment No. 2)* Verona Pharma plc (Name of Issuer) Ordinary Shares (Title of Class of Securities) 925050106 (CUSIP Number) OrbiMed Advisors LLC OrbiMed Capital GP VI LLC OrbiMed Capital LLC 601 Lexington Avenue, 54th Floor

August 12, 2022 8-K

Financial Statements and Exhibits, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): August 10, 2022 Verona Pharma plc (Exact name of registrant as specified in its charter) United Kingdom 001-38067 98-1489389 (State or other jurisdiction of incorporation) (Commission

August 12, 2022 EX-1.1

Underwriting Agreement, dated as of August 10, 2022, by and among Verona Pharma plc, Jefferies LLC, Piper Sandler & Co. and Truist Securities, Inc., as representatives of the several underwriters named therein.

EX-1.1 2 tm2222808d3ex1-1.htm EXHIBIT 1.1 Exhibit 1.1 Execution Version Verona Pharma plc 12,400,000 American Depositary Shares Each Representing Eight Ordinary Shares (Nominal value £0.05 Per Share) UNDERWRITING AGREEMENT August 10, 2022 JEFFERIES LLC PIPER SANDLER & CO. TRUIST SECURITIES, INC. As Representatives of the several Underwriters c/o Jefferies LLC 520 Madison Avenue New York, New York

August 11, 2022 SC 13D/A

VRNA / Verona Pharma plc / Abingworth LLP - SC 13D/A Activist Investment

SC 13D/A SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13D Under the Securities Exchange Act of 1934 (Amendment No. 2)* Verona Pharma plc (Name of Issuer) Ordinary Shares, nominal value £0.05 per share (Title of Class of Securities) 925050106 (CUSIP Number) John Heard Abingworth LLP Princes House 38 Jermyn Street London, England SW1Y 6DN +44 20 7534 1500 (Name, Address and Tel

August 11, 2022 424B5

12,400,000 American Depositary Shares (Representing Ordinary Shares) Verona Pharma plc

TABLE OF CONTENTS ?Filed Pursuant to Rule 424(b)(5)? ?Registration No. 333-254530? PROSPECTUS SUPPLEMENT (To Prospectus dated March 29, 2021) 12,400,000 American Depositary Shares (Representing Ordinary Shares)? Verona Pharma plc ? We are offering 12,400,000 American Depositary Shares, or ADSs. Each ADS represents eight ordinary shares of Verona Pharma plc, nominal value ?0.05 each. Our ADSs are l

August 10, 2022 SC 13G/A

VRNA / Verona Pharma plc / Access Industries Holdings LLC - SC 13G/A Passive Investment

SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 1)* Verona Pharma plc (Name of Issuer) Ordinary shares, nominal value ?0.05 per share (Title of Class of Securities) 925050106** (CUSIP Number) August 9, 2022 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant

August 9, 2022 EX-99.1

Verona Pharma Reports Second Quarter 2022 Financial Results and Provides Corporate Update Ensifentrine met primary and secondary endpoints of evaluating lung function in Phase 3 ENHANCE-2 trial for COPD Top-line Phase 3 ENHANCE-1 data expected around

Verona Pharma Reports Second Quarter 2022 Financial Results and Provides Corporate Update Ensifentrine met primary and secondary endpoints of evaluating lung function in Phase 3 ENHANCE-2 trial for COPD Top-line Phase 3 ENHANCE-1 data expected around the end of 2022 Conference call today at 8:30 a.

August 9, 2022 8-K

Regulation FD Disclosure, Financial Statements and Exhibits, Results of Operations and Financial Condition, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): August 9, 2022 Verona Pharma plc (Exact name of registrant as specified in its charter) United Kingdom 001-39067 98-1489389 (State or other jurisdiction of incorporation) (Commission

August 9, 2022 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2022 ☐ TRANSITION REPORT PURSUANT TO S

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2022 OR ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 FOR THE TRANSITION PERIOD FROM TO Commission File Number: 001-38067 Verona Pharma plc (Ex

August 9, 2022 EX-99.2

ENHANCE-2 Phase 3 data August 2022 Nasdaq: VRNA | www.veronapharma.com Forward-looking statements This presentation contains “forward‐looking” statements that are based on the beliefs and assumptions and on information currently available to manageme

vrnaenh2datacallslidesf ENHANCE-2 Phase 3 data August 2022 Nasdaq: VRNA | www.veronapharma.com Forward-looking statements This presentation contains “forward‐looking” statements that are based on the beliefs and assumptions and on information currently available to management of Verona Pharma plc (together with its consolidated subsidiaries, the “Company”). All statements other than statements of

August 9, 2022 424B5

SUBJECT TO COMPLETION, DATED AUGUST 9, 2022

TABLE OF CONTENTS The information in this preliminary prospectus supplement and the accompanying prospectus, relating to an effective registration statement under the Securities Act of 1933, as amended, is not complete and may be changed.

May 3, 2022 EX-99.1

Verona Pharma Reports First Quarter 2022 Financial Results and Provides Corporate Update Phase 3 ENHANCE-2 trial on target to report top-line COPD data in Q3 2022 James Brady joined the Board as Non-Executive Director Conference call today at 9:00 a.

Verona Pharma Reports First Quarter 2022 Financial Results and Provides Corporate Update Phase 3 ENHANCE-2 trial on target to report top-line COPD data in Q3 2022 James Brady joined the Board as Non-Executive Director Conference call today at 9:00 a.

May 3, 2022 EX-10.1

Second Amendment to Loan and Security Agreement, dated as of March 2, 2022, by and among Silicon Valley Bank, Verona Pharma plc and Verona Pharma, Inc.

297684974.1 SECOND AMENDMENT TO LOAN AND SECURITY AGREEMENT This Second Amendment to Loan and Security Agreement (this ?Amendment?) is entered into this 2nd day of March, 2022, by and between (a) SILICON VALLEY BANK, a California corporation (?Bank?) and (b) VERONA PHARMA PLC., a company registered under the laws of England and Wales with company number 05375156 (?Parent? or ?UK Borrower?) and VER

May 3, 2022 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2022 ☐ TRANSITION REPORT PURSUANT TO

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2022 OR ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 FOR THE TRANSITION PERIOD FROM TO Commission File Number: 001-38067 Verona Pharma plc (E

May 3, 2022 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): May 3, 2022 Verona Pharma plc (Exact name of registrant as specified in its charter) United Kingdom 001-39067 98-1489389 (State or other jurisdiction of incorporation) (Commission Fil

April 29, 2022 8-K

Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): April 27, 2022 Verona Pharma plc (Exact name of registrant as specified in its charter) United Kingdom 001-38067 98-1489389 (State or other jurisdiction of incorporation) (Commission

March 30, 2022 8-K

Entry into a Material Definitive Agreement, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): March 24, 2022 Verona Pharma plc (Exact name of registrant as specified in its charter) United Kingdom 001-38067 98-1489389 (State or other jurisdiction of incorporation) (Commission

March 30, 2022 EX-10.1

Amendment Agreement by and between Verona Pharma plc and Ligand U.K. Development Limited dated March 23, 2022

Exhibit 10.1 Confidential and Without Prejudice Amendment Agreement THIS AMENDMENT AGREEMENT (this ?Amendment?) is made the 24th day of March 2022 BETWEEN: (1) Verona Pharma plc, a company incorporated under the laws of England and Wales, under company registration number 05375156 whose registered office is at One Central Square, Cardiff, CF10 1FS, United Kingdom (?Verona?); and (2) Ligand UK Deve

March 22, 2022 DEF 14A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amend

TABLE OF CONTENTS UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549? ? SCHEDULE 14A (Rule 14a-101)? INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.

March 16, 2022 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): March 14, 2022 Verona Pharma plc (Exact name of registrant as specified in its charter) United Kingdom 001-39067 98-1489389 (State or other jurisdiction of incorporation) (Commission

March 3, 2022 EX-10.4.8

Renewal Agreement to Lease by and between the Verona Pharma plc and Regus Management (U.K.) Limited dated December 7, 2021

04/01/2022, 11:10 Regus https://serviceagreement.regus.com/ServiceAgreement.aspx?id=4717c5f6853dd453481216da462cc186&user=regus&term=12&mostRecentVersi? 1/1 Renewal Agreement: Agreement Date : 7 December 2021 Confirmation No : R-2030978 Business Centre Details London - London Bridge Client Details Company Name VERONA PHARMA PLC Phone +44 20 3223 4200 Email [email protected] Service Provis

March 3, 2022 EX-10.4.7

Renewal Agreement to Lease by and between the Verona Pharma plc and Regus Management (U.K.) Limited dated November 9, 2021

Renewal Agreement: THIS AGREEMENT HAS BEEN UPDATED PLEASE CLICK THE LINK BELOW TO VIEW THE MOST RECENT VERSION.

March 3, 2022 EX-99.1

Verona Pharma Reports Fourth Quarter and Full Year 2021 Financial Results and Provides Corporate Update Phase 3 ENHANCE program on track to report top-line COPD data in 2022 Conference call today at 9:00 a.m. EST / 2:00 p.m. GMT

Verona Pharma Reports Fourth Quarter and Full Year 2021 Financial Results and Provides Corporate Update Phase 3 ENHANCE program on track to report top-line COPD data in 2022 Conference call today at 9:00 a.

March 3, 2022 EX-10.4.9

Agreement to Lease by and between the Verona Pharma Inc. and Brier Creek Office #4, LLC dated March 6, 2020

BRIER CREEK OFFICE PARK WAKE COUNTY, NORTH CAROLINA LEASE BETWEEN BRIER CREEK OFFICE #4, LLC Landlord, AND VERONA PHARMA INC.

March 3, 2022 EX-21.1

List of Subsidiaries of Verona Pharma plc

Exhibit 21.1 SUBSIDIARIES OF VERONA PHARMA PLC Legal Name of Subsidiary Jurisdiction of Organization Verona Pharma, Inc. Delaware

March 3, 2022 EX-10.19.3

Second Amendment to Loan and Security Agreement, dated as of March 2, 2022, by and among Silicon Valley Bank, Verona Pharma plc and Verona Pharma, Inc.

CERTAIN INFORMATION IN THIS DOCUMENT, MARKED BY [***], HAS BEEN EXCLUDED PURSUANT TO REGULATION S-K, ITEM 601(b)(10)(iv).

March 3, 2022 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): March 3, 2022 Verona Pharma plc (Exact name of registrant as specified in its charter) United Kingdom 001-39067 98-1489389 (State or other jurisdiction of incorporation) (Commission F

March 3, 2022 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K ☒ ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2021 ☐ TRANSITION REPORT PURSUANT TO SECTI

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K ? ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2021 OR ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 FOR THE TRANSITION PERIOD FROM TO Commission File Number: 001-38067 Verona Pharma plc (Exact

February 14, 2022 SC 13G/A

VRNA / Verona Pharma plc / RA CAPITAL MANAGEMENT, L.P. - SC 13G/A Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 13G/A Under the Securities Exchange Act of 1934 (Amendment No. 1)* Verona Pharma plc (Name of Issuer) Ordinary Shares, nominal value ?0.05 per share American Depositary Shares, each representing eight Ordinary Shares (Title of Class of Securities) 925050106 (CUSIP Number) December 31, 2021 (Date of Event Which Require

February 11, 2022 SC 13G/A

VRNA / Verona Pharma plc / Vivo Ventures VI, LLC - AMENDMENT NO. 2 TO SCHEDULE 13G Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G/A Under the Securities Exchange Act of 1934 (Amendment No. 2) * VERONA PHARMA PLC (Name of Issuer) Ordinary Shares, nominal value ?0.05 per share (Title of Class of Securities) 925050106 (CUSIP Number) December 31, 2021 (Date of Event which Requires Filing of this Statement) Check the appropriate box to designate

February 4, 2022 SC 13G

VRNA / Verona Pharma plc / WELLINGTON MANAGEMENT GROUP LLP - SEC SCHEDULE 13G Passive Investment

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* Verona Pharma PLC (Name of Issuer) Common Stock (Title of Class of Securities) G9337X139 (CUSIP Number) December 31, 2021 (Date of Event Which Requires Filing of this Statement) Check the appropriate box to designate the rule pursuant to which this Schedu

January 5, 2022 EX-99.1

Verona Pharma Completes Enrollment in ENHANCE-1 48-week Subset ENHANCE-2 Screening Complete with Full Enrollment Expected in January 2022 ENHANCE Phase 3 Program on Track to Report Top-line Data in 2022

Exhibit 99.1 Verona Pharma Completes Enrollment in ENHANCE-1 48-week Subset ENHANCE-2 Screening Complete with Full Enrollment Expected in January 2022 ENHANCE Phase 3 Program on Track to Report Top-line Data in 2022 LONDON and RALEIGH, N.C., January 5, 2022 ? Verona Pharma plc (Nasdaq: VRNA) (?Verona Pharma? or the ?Company?), a clinical-stage biopharmaceutical company focused on respiratory disea

January 5, 2022 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition, Other Events

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): January 5, 2022 Verona Pharma plc (Exact name of registrant as specified in its charter) United Kingdom 001-39067 Not Applicable (State or other jurisdiction of incorporation) (Commis

November 9, 2021 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2021 ☐ TRANSITION REPORT PURSUANT

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended September 30, 2021 OR ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 FOR THE TRANSITION PERIOD FROM TO Commission File Number: 001-38067 Verona Pharma pl

November 9, 2021 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): November 9, 2021 Verona Pharma plc (Exact name of registrant as specified in its charter) United Kingdom 001-39067 98-1489389 (State or other jurisdiction of incorporation) (Commissio

November 9, 2021 EX-99.1

Verona Pharma Reports Third Quarter 2021 Financial Results and Provides Corporate Update Enrollment in ENHANCE-1 48-week subset and ENHANCE-2 expected to complete around year-end 2021 ENHANCE Phase 3 program on track to report top-line data in 2022 C

Verona Pharma Reports Third Quarter 2021 Financial Results and Provides Corporate Update Enrollment in ENHANCE-1 48-week subset and ENHANCE-2 expected to complete around year-end 2021 ENHANCE Phase 3 program on track to report top-line data in 2022 Conference call today at 9:00 a.

August 11, 2021 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers, Financial Statements and Exhibits

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): August 9, 2021 Verona Pharma plc (Exact name of registrant as specified in its charter) United Kingdom 001-39067 Not Applicable (State or other jurisdiction of incorporation) (Commiss

August 11, 2021 EX-10.1

Employee Change in Control Severance Benefit Plan

Exhibti 10.1 Verona Pharma plc (the ?Company?) EMPLOYEE CHANGE IN CONTROL SEVERANCE BENEFIT PLAN Adopted by the Remuneration Committee on August 9, 2021 Section 1. Introduction. This Verona Pharma Employee Change in Control Severance Benefit Plan (the ?Plan?) is hereby adopted effective as of August 9, 2021 (the ?Effective Date?). The purpose of the Plan is to provide for the payment of severance

August 5, 2021 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): August 5, 2021 Verona Pharma plc (Exact name of registrant as specified in its charter) United Kingdom 001-39067 98-1489389 (State or other jurisdiction of incorporation) (Commission

August 5, 2021 EX-99.1

Verona Pharma Reports Second Quarter 2021 Financial Results and Provides Corporate Update ENHANCE Phase 3 program on track to report top-line data in 2022 Up to $219 million strategic collaboration with Nuance Pharma in Greater China Conference call

Verona Pharma Reports Second Quarter 2021 Financial Results and Provides Corporate Update ENHANCE Phase 3 program on track to report top-line data in 2022 Up to $219 million strategic collaboration with Nuance Pharma in Greater China Conference call today at 8:30 a.

August 5, 2021 EX-10.1

Collaboration and License Agreement, effective as of June 9, 2021, by and between Verona Pharma plc, Nuance Pharma Limited and Nuance (Shanghai) Pharma Co Ltd

Exhibit 10.1 CERTAIN INFORMATION IN THIS DOCUMENT, MARKED BY [***], HAS BEEN EXCLUDED PURSUANT TO REGULATION S-K, ITEM 601(b)(10)(iv). SUCH EXCLUDED INFORMATION IS NOT MATERIAL AND IS THE TYPE THAT THE REGISTRANT TREATS AS PRIVATE OR CONFIDENTIAL. COLLABORATION AND LICENSE AGREEMENT BY AND BETWEEN VERONA PHARMA PLC AND NUANCE PHARMA LIMITED AND NUANCE (SHANGHAI) PHARMA CO LTD TABLE OF CONTENTS Pag

August 5, 2021 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q ☒ QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2021 ☐ TRANSITION REPORT PURSUANT TO S

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended June 30, 2021 OR ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 FOR THE TRANSITION PERIOD FROM TO Commission File Number: 001-38067 Verona Pharma plc (Ex

July 20, 2021 8-K/A

Entry into a Material Definitive Agreement

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K/A (Amendment No. 1) CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): July 15, 2021 (June 9, 2021) Verona Pharma plc (Exact name of registrant as specified in its charter) United Kingdom 001-39067 Not Applicable (State or other juris

June 11, 2021 8-K

Entry into a Material Definitive Agreement

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): June 9, 2021 Verona Pharma plc (Exact name of registrant as specified in its charter) United Kingdom 001-39067 Not Applicable (State or other jurisdiction of incorporation) (Commissio

May 3, 2021 8-K

Submission of Matters to a Vote of Security Holders

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): April 27, 2021 Verona Pharma plc (Exact name of registrant as specified in its charter) United Kingdom 001-39067 Not Applicable (State or other jurisdiction of incorporation) (Commiss

April 29, 2021 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): April 29, 2021 Verona Pharma plc (Exact name of registrant as specified in its charter) United Kingdom 001-39067 Not Applicable (State or other jurisdiction of incorporation) (Commiss

April 29, 2021 EX-99.1

Verona Pharma Reports First Quarter 2021 Financial Results and Provides Corporate Update ENHANCE Phase 3 program enrollment continues on track to complete in 2H21 Board strengthened with NED appointment of Lisa Deschamps Conference call today at 9:00

Exhibit 99.1 Verona Pharma Reports First Quarter 2021 Financial Results and Provides Corporate Update ENHANCE Phase 3 program enrollment continues on track to complete in 2H21 Board strengthened with NED appointment of Lisa Deschamps Conference call today at 9:00 a.m. EDT / 2:00 p.m. BST LONDON and RALEIGH, N.C., April 29, 2021 ? Verona Pharma plc (Nasdaq: VRNA) (?Verona Pharma? or the ?Company?),

April 29, 2021 10-Q

Quarterly Report - 10-Q

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-Q ? QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the quarterly period ended March 31, 2021 OR ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 FOR THE TRANSITION PERIOD FROM TO Commission File Number: 001-38067 Verona Pharma plc (E

March 26, 2021 CORRESP

March 26, 2021

March 26, 2021 Via EDGAR Transmission United States Securities and Exchange Commission Division of Corporation Finance Office of Life Sciences 100 F Street, N.

March 19, 2021 S-3

- S-3

TABLE OF CONTENTS As filed with the Securities and Exchange Commission on March 19, 2021 Registration No.

March 19, 2021 DEF 14A

Definitive Proxy Statement on Schedule 14A, filed with the SEC on March 19, 2021

TABLE OF CONTENTS UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, DC 20549 ? SCHEDULE 14A (Rule 14a-101) INFORMATION REQUIRED IN PROXY STATEMENT SCHEDULE 14A INFORMATION Proxy Statement Pursuant to Section 14(a) of the Securities Exchange Act of 1934 (Amendment No.

March 19, 2021 EX-4.5

Form of Indenture.

Exhibit 4.5 Verona Pharma plc INDENTURE Dated as of , 20 [] Trustee TABLE OF CONTENTS Page ARTICLE I. DEFINITIONS AND INCORPORATION BY REFERENCE 1 Section 1.1. Definitions 1 Section 1.2. Other Definitions. 5 Section 1.3. Incorporation by Reference of Trust Indenture Act 5 Section 1.4. Rules of Construction 5 ARTICLE II. THE SECURITIES 6 Section 2.1. Issuable in Series 6 Section 2.2. Establishment

March 19, 2021 POS AM

- POS AM

TABLE OF CONTENTS As filed with the Securities and Exchange Commission on March 19, 2021 Registration No.

March 19, 2021 EX-1.2

, dated as of March 19, 2021, between Verona Pharma plc and Jefferies LLC.

EX-1.2 2 tm2110174d2ex1-2.htm EXHIBIT 1.2 EXHIBIT 1.2 OPEN MARKET SALE AGREEMENT March 19, 2021 JEFFERIES LLC 520 Madison Avenue New York, New York 10022 Ladies and Gentlemen: Verona Pharma plc, a public limited company incorporated under the laws of England and Wales with registered number 5375156 (the “Company”), proposes, subject to the terms and conditions stated herein, to issue and sell from

March 2, 2021 8-K

Departure of Directors or Certain Officers; Election of Directors; Appointment of Certain Officers; Compensatory Arrangements of Certain Officers

8-K 1 tm218427d18k.htm FORM 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): February 24, 2021 Verona Pharma plc (Exact name of registrant as specified in its charter) United Kingdom 001-39067 Not Applicable (State or other juri

February 25, 2021 EX-10.20

Form of Non-Executive Director letter of appointment

DRAFT PRIVATE AND CONFIDENTIAL [Name] [Address] [Date] Dear [Name], Letter of appointment as a non-executive director On behalf of the board of directors (?Board?) of Verona Pharma plc (?Company?), it is with pleasure that I confirm your appointment as a non-executive director of the Company, with effect from [Date] (?Effective Date?) and to set out your duties, terms of appointment and remuneration.

February 25, 2021 8-K

Financial Statements and Exhibits, Results of Operations and Financial Condition

8-K 1 tm217921d18k.htm FORM 8-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): February 25, 2021 Verona Pharma plc (Exact name of registrant as specified in its charter) United Kingdom 001-39067 Not Applicable (State or other juri

February 25, 2021 10-K

Annual Report - 10-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 10-K ? ANNUAL REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 For the fiscal year ended December 31, 2020 OR ? TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934 FOR THE TRANSITION PERIOD FROM TO Commission File Number: 001-38067 Verona Pharma plc (Exact

February 25, 2021 EX-10.19.2

First Amendment to Loan and Security Agreement, dated as of November 19, 2020, by and among Silicon Valley Bank, Verona Pharma plc and Verona Pharma, Inc.

FIRST AMENDMENT TO LOAN AND SECURITY AGREEMENT This First Amendment to Loan and Security Agreement (this ?Amendment?) is entered into this 28th day of January, 2021, by and between SILICON VALLEY BANK, a California corporation (?Bank?) and VERONA PHARMA PLC.

February 25, 2021 EX-4.5

Description of Securities

DESCRIPTION OF SECURITIES DESCRIPTION OF SHARE CAPITAL AND ARTICLES OF ASSOCIATION Set forth below is a summary of certain information concerning the share capital of Verona Pharma plc (the ?Company,? ?we,? ?us,? and ?our?) as well as a description of certain provisions of our articles of association and relevant provisions of English law.

February 25, 2021 EX-99.1

Verona Pharma Reports Fourth Quarter and Full Year 2020 Financial Results and Provides Corporate Update Positive Phase 2 results with pMDI ensifentrine in COPD Enrollment ongoing in ENHANCE Phase 3 program Up to $30 million debt finance facility incr

Exhibit 99.1 Verona Pharma Reports Fourth Quarter and Full Year 2020 Financial Results and Provides Corporate Update Positive Phase 2 results with pMDI ensifentrine in COPD Enrollment ongoing in ENHANCE Phase 3 program Up to $30 million debt finance facility increases financial flexibility Conference call today at 9:00 a.m. EST / 2:00 p.m. GMT LONDON and RALEIGH, N.C., February 25, 2021 – Verona P

February 16, 2021 SC 13G

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* Verona Pharma plc (Name of Issuer) Ordinary Shares, nominal value £0.05 per share American Depositary Sha

UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* Verona Pharma plc (Name of Issuer) Ordinary Shares, nominal value £0.05 per share American Depositary Shares, each representing eight Ordinary Shares (Title of Class of Securities) 925050106 (CUSIP Number) December 31, 2020 (Date of Event Which Requires F

February 5, 2021 SC 13G/A

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 2)* Verona Pharma plc (Name of Issuer) Ordinary Shares, nominal value £0.05 per share American Depositary Sh

Amendment No. 2 to Schedule 13G UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. 2)* Verona Pharma plc (Name of Issuer) Ordinary Shares, nominal value £0.05 per share American Depositary Shares, each representing eight Ordinary Shares (Title of class of securities) 925050106** (CUSIP number) February 2, 20

January 25, 2021 8-K

Results of Operations and Financial Condition - FORM 8-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 8-K CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of report (Date of earliest event reported): January 25, 2021 Verona Pharma plc (Exact name of registrant as specified in its charter) United Kingdom 001-39067 Not Applicable (State or other jurisdiction of incorporation) (Commi

January 4, 2021 424B3

EXPLANATORY NOTE

Filed Pursuant to Rule 424(b)(3) Registration No. 333-225107 EXPLANATORY NOTE As of January 1, 2021, Verona Pharma plc, or the Company, commenced reporting as a domestic issuer under the Securities Exchange Act of 1934, as amended, or the Exchange Act. In connection with such reporting, the Company is filing this prospectus supplement as part of the Registration Statement on Form F-3 (File No. 333

December 30, 2020 6-K

Current Report of Foreign Issuer - FORM 6-K

6-K 1 tm2039594d16k.htm FORM 6-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of December 2020 Commission File Number: 001-38067 Verona Pharma plc (Translation of registrant's name into English) 3 More London Riverside London SE1 2RE UK +44

December 30, 2020 EX-1

Articles of Association, as amended and as currently in effect

Exhibit 1 THE COMPANIES ACT 2006 PUBLIC COMPANY LIMITED BY SHARES ARTICLES OF ASSOCIATION - of - Verona Pharma plc (as adopted by Special Resolution on 18 December 2020) TABLE OF CONTENTS 1.

November 24, 2020 EX-1.2

Term Loan Announcement

EX-1.2 3 tm2036424d1ex1-2.htm EXHIBIT 1.2 Exhibit 1.2 Verona Pharma Secures up to $30 Million Debt Financing from Silicon Valley Bank Non-dilutive capital to provide further financial flexibility LONDON and RALEIGH, N.C., November 23, 2020 – Verona Pharma plc (Nasdaq: VRNA) (“Verona Pharma” or the “Company”), a clinical-stage biopharmaceutical company focused on respiratory diseases, announces tha

November 24, 2020 6-K

Current Report of Foreign Issuer - FORM 6-K

6-K 1 tm2036424-16k.htm FORM 6-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of November 2020 Commission File Number: 001-38067 Verona Pharma plc (Translation of registrant's name into English) 3 More London Riverside London SE1 2RE UK +44

November 24, 2020 EX-1.1

Loan and Security Agreement, dated as of November 19, 2020, by and among Silicon Valley Bank, Verona Pharma plc and Verona Pharma, Inc.

EX-1.1 2 tm2036424d1ex1-1.htm EXHIBIT 1.1 Exhibit 1.1 [***] Certain information in this document has been excluded in accordance with applicable Securities and Exchange Commission rules and regulations. Such excluded information is not material and would likely cause competitive harm to the registrant if publicly disclosed. Execution Version LOAN AND SECURITY AGREEMENT THIS LOAN AND SECURITY AGREE

November 12, 2020 6-K

Current Report of Foreign Issuer - 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of November 2020 Commission File Number: 001-38067 Verona Pharma plc (Translation of registrant's name into English) 3 More London Riverside London SE1 2RE UK +44 203 283 4200 (Address of principa

November 12, 2020 EX-1

Notice of General Meeting of Verona Pharma plc.

a260051veronapharma-noti THIS DOCUMENT AND THE ENCLOSED FORM OF PROXY ARE IMPORTANT AND REQUIRE YOUR IMMEDIATE ATTENTION.

November 12, 2020 EX-3

Proposed Articles of Association, marked to show changes.

veronapharmaamendedartic THE COMPANIES ACT 2006 PUBLIC COMPANY LIMITED BY SHARES ARTICLES OF ASSOCIATION - of - Verona Pharma plc (as adopted by Special Resolution on 8th February 2017) on 2020) TABLE OF CONTENTS 1.

November 12, 2020 EX-2

Form of Proxy.

veronapharmadec182020gmp VERONA PHARMA PLC FORM OF PROXY I/We ……………………………………………………………………………………………………………….

October 29, 2020 EX-1

Verona Pharma plc Interim Results for the

Verona Pharma plc Operational Update and Financial Results for the Three and Nine Months Ended September 30, 2020 Initiated ENHANCE Phase 3 clinical trials in COPD Completed $200 million private placement Commenced a pilot clinical study in U.

October 29, 2020 6-K

Current Report of Foreign Issuer - 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of October 2020 Commission File Number: 001-38067 Verona Pharma plc (Translation of registrant's name into English) 3 More London Riverside London SE1 2RE UK +44 203 283 4200 (Address of principal

October 5, 2020 SC 13D/A

VRNA / Verona Pharma plc / Novo Holdings A/S - SC 13D/A Activist Investment

SC 13D/A UNITED STATES SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 SCHEDULE 13D Under the Securities Exchange Act of 1934 (Amendment No. 2)* Verona Pharma plc (Name of Issuer) Ordinary Shares, nominal value £0.05 per share American Depositary Shares, each representing eight Ordinary Shares (Title of Class of Securities) 925050106 (CUSIP Number) Peter Haahr Novo Holdings A/S Tuborg Ha

September 25, 2020 6-K

Current Report of Foreign Issuer - 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of September 2020 Commission File Number: 001-38067 Verona Pharma plc (Translation of registrant's name into English) 3 More London Riverside London SE1 2RE UK +44 203 283 4200 (Address of princip

September 25, 2020 EX-1.1

Initiation of Phase 3 Announcement

Verona Pharma Initiates Phase 3 Clinical Trials with Nebulized Ensifentrine for the Maintenance Treatment of COPD LONDON and RALEIGH, N.

September 22, 2020 EX-2

AIM Delisting Frequently Asked Questions

AIM DELISTING – INFORMATION FOR HOLDERS OF ORDINARY SHARES AND FREQUENTLY ASKED QUESTIONS On September 21, 2020, Verona Pharma plc (“Verona Pharma” or the “Company”) announced the intended cancellation of its Ordinary Shares from admission to trading on AIM (the “AIM Delisting”).

September 22, 2020 6-K

Current Report of Foreign Issuer - 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of September 2020 Commission File Number: 001-38067 Verona Pharma plc (Translation of registrant's name into English) 3 More London Riverside London SE1 2RE UK +44 203 283 4200 (Address of princip

September 22, 2020 EX-1

AIM Delisting Announcement

THIS ANNOUNCEMENT CONTAINS INSIDE INFORMATION FOR THE PURPOSES OF ARTICLE 7 OF THE MARKET ABUSE REGULATION (EU) NO.

September 14, 2020 6-K

Current Report of Foreign Issuer - 6-K

6-K 1 a20200914covid-19initi.htm 6-K UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of September 2020 Commission File Number: 001-38067 Verona Pharma plc (Translation of registrant's name into English) 3 More London Riverside London SE1 2RE UK

September 14, 2020 EX-1.1

ilot Study Announcement

Verona Pharma Initiates Pilot Study with pMDI Ensifentrine in U.S. Patients Hospitalized with COVID-19 LONDON and RALEIGH, N.C., September 8, 2020 – Verona Pharma plc (AIM: VRP) (Nasdaq: VRNA) (“Verona Pharma”), a clinical-stage biopharmaceutical company focused on respiratory diseases, announces the initiation of a pilot study to investigate the efficacy and safety of ensifentrine delivered via p

August 27, 2020 6-K

Current Report of Foreign Issuer - 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of August 2020 Commission File Number: 001-38067 Verona Pharma plc (Translation of registrant's name into English) 3 More London Riverside London SE1 2RE UK +44 203 283 4200 (Address of principal

August 27, 2020 EX-1.1

Grant of RADSUs and PDMR Dealings

Grant of RADSUs and PDMR Dealings LONDON and RALEIGH, N.C., August 26, 2020 – Verona Pharma plc (AIM:VRP) (Nasdaq:VRNA) (“Verona Pharma” or the “Company”), a clinical-stage biopharmaceutical company focused on respiratory diseases, announces that, on August 20, 2020 it granted 6,794,521 Restricted American Depositary Share Units (“RADSUs”), representing 54,356,168 ordinary shares of 5 pence each (

August 25, 2020 CORRESP

-

August 25, 2020 Via EDGAR Transmission Division of Corporation Finance Securities and Exchange Commission 100 F Street, N.

August 25, 2020 F-1/A

Powers of Attorney (incorporated by reference to the signature page hereto).

TABLE OF CONTENTS As filed with the Securities and Exchange Commission on August 25, 2020 Registration No.

August 25, 2020 EX-1

Unaudited financial statements for Verona Pharma plc for the three- and six-month periods ended June 30, 2020

Exhibit 1 VERONA PHARMA PLC CONDENSED CONSOLIDATED INTERIM STATEMENTS OF FINANCIAL POSITION (UNAUDITED) AS OF JUNE 30, 2020, AND DECEMBER 31, 2019 Notes As of June 30, 2020 As of December 31, 2019 £'000s £'000s ASSETS Non-current assets: Goodwill 441 441 Intangible assets 9 25,430 2,757 Property, plant and equipment 37 43 Right-of-use asset 10 1,096 971 Total non-current assets 27,004 4,212 Curren

August 25, 2020 6-K/A

Form 6-K furnished to the SEC on August 25, 2020

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K/A REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of August 2020 Commission File Number: 001-38067 Verona Pharma plc (Translation of registrant's name into English) 3 More London Riverside London SE1 2RE UK +44 203 283 4200 (Address of principa

August 20, 2020 S-8

- FORM S-8

As filed with the Securities and Exchange Commission on August 20, 2020 Registration No.

August 19, 2020 6-K

Current Report of Foreign Issuer - 6-K

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of August 2020 Commission File Number: 001-38067 Verona Pharma plc (Translation of registrant's name into English) 3 More London Riverside London SE1 2RE UK +44 203 283 4200 (Address of principal

August 19, 2020 EX-1.1

pMDI Part B Announcement

EX-1.1 2 vrnapmdipartbstrtfinal.htm EX-1.1 Verona Pharma Initiates Multiple Dose Part of Phase 2 Clinical Trial with pMDI Formulation of Ensifentrine in COPD Results expected in the first half of 2021 LONDON and RALEIGH, N.C., August 19, 2020 – Verona Pharma plc (AIM: VRP) (Nasdaq: VRNA) (“Verona Pharma”), a clinical-stage biopharmaceutical company focused on respiratory diseases, announces the in

August 17, 2020 F-1

Form F-1 (Registration No. 333-247928)

F-1 1 tm2027314-1f1.htm F-1 TABLE OF CONTENTS As filed with the Securities and Exchange Commission on August 17, 2020 Registration No. 333-      UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 Form F-1 REGISTRATION STATEMENT UNDER THE SECURITIES ACT OF 1933 VERONA PHARMA PLC (Exact Name of Registrant as Specified in its Charter) Not Applicable (Translation of Registrant’s N

August 17, 2020 EX-10.12

Employment Agreement, dated February 1, 2020, between Verona Pharma Inc. and Mark Hahn

Exhibit 10.12 January 28, 2020 Mark Hahn XXXXXXXXX XXXXXXXXX Re: Offer of Employment Dear Mark: On behalf of Verona Pharma Inc. (the “Company” or “Verona Pharma”), I am pleased to offer you employment with the Company. This offer letter agreement, together with Exhibit A hereto (together, the “Agreement”) sets forth the terms of employment the Company is offering you. If you accept this offer, we

August 14, 2020 6-K

Form 6-K furnished to the SEC on August 14, 2020

UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 FORM 6-K REPORT OF FOREIGN PRIVATE ISSUER PURSUANT TO RULE 13a-16 OR 15d-16 UNDER THE SECURITIES EXCHANGE ACT OF 1934 For the month of August 2020 Commission File Number: 001-38067 Verona Pharma plc (Translation of registrant's name into English) 3 More London Riverside London SE1 2RE UK +44 203 283 4200 (Address of principal

August 14, 2020 EX-1

Verona Pharma plc Interim Results for the six months ended June 30,

Verona Pharma plc Operational Update and Financial Results for the Three and Six Months Ended June 30, 2020 Completed $200 million private placement post period Phase 3 COPD clinical trials planned to start later this year Pilot clinical study in patients hospitalized with COVID-19 planned to start in the third quarter Conference Call Today at 9:00 am EDT / 2:00 pm BST LONDON, UK and RALEIGH, NC, August 14, 2020 – Verona Pharma plc (AIM: VRP) (Nasdaq: VRNA) (“Verona Pharma” or the “Company”), a clinical-stage biopharmaceutical company focused on developing and commercializing innovative therapies for respiratory diseases, announces financial results for the three and six months ended June 30, 2020 and provides a corporate update.

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