ACAD / ACADIA Pharmaceuticals Inc. - Insider Trading and Ownership Report - SEC Form 3, 4, 5

ACADIA Pharmaceuticals Inc.
US ˙ NasdaqGS ˙ US0042251084

Jumlah Saham Beredar 168,712,220 shares
Saham Orang Dalam47,784,968 shares
Kepemilikan oleh Orang Dalam28.32 %
Orang Dalam Sejati51
Skor Sentimen Orang Dalam

Skor Sentimen Orang Dalam mengidentifikasi perusahaan yang dibeli oleh orang dalam korporat.

Ini adalah hasil dari model kuantitatif multifaktor yang canggih yang mengidentifikasi perusahaan dengan tingkat akumulasi internal tertinggi. Model penilaian ini menggunakan kombinasi dari jumlah bersih orang dalam yang membeli dalam 90 hari sebelumnya, total saham yang dibeli sebagai persentase dari jumlah saham yang beredar, dan total saham yang dimiliki oleh orang dalam. Angka tersebut berkisar dari 0 hingga 100, dengan angka yang lebih tinggi menunjukkan tingkat akumulasi yang lebih tinggi dibandingkan dengan perusahaan sejenis, dan 50 adalah rata-rata.

Frekuensi Pembaruan: Setiap Hari

Lihat Pilihan Teratas dari Orang Dalam, yang menyediakan daftar perusahaan dengan akumulasi orang dalam tertinggi.

Lihat Saham dengan Peringkat Tertinggi
Skor Sentimen Petugas

Skor Sentimen Pejabat menemukan perusahaan yang dibeli oleh Pejabat Korporat.

Menurut definisi, Pejabat Korporasi adalah Orang Dalam Korporasi, tetapi tidak seperti beberapa Orang Dalam lainnya (Pemegang Saham 10% dan Anggota Dewan), Pejabat bekerja untuk perusahaan setiap hari, dan mereka menggunakan uang mereka sendiri saat bertransaksi . (Pemegang Saham 10% dan Anggota Dewan seringkali adalah manajer dana yang mengelola uang orang lain.) Dengan demikian, transaksi orang dalam yang dilakukan oleh Pejabat jauh lebih signifikan dan harus ditangani dengan tepat.

Seperti Skor Sentimen Internal, Skor Sentimen Pejabat adalah hasil dari model kuantitatif multi-faktor yang canggih yang mengidentifikasi perusahaan dengan tingkat akumulasi pejabat tertinggi.

Frekuensi Pembaruan: Setiap Hari

Lihat Pilihan Teratas dari Orang Dalam, yang menyediakan daftar perusahaan dengan sentimen orang dalam tertinggi.

Lihat Saham dengan Peringkat Tertinggi
Metrik Utama Orang Dalam

Kartu ini menunjukkan peringkat perusahaan berdasarkan berbagai metrik internal. Peringkat persentil menunjukkan bagaimana perusahaan ini dibandingkan dengan perusahaan lain di pasar AS. Peringkat yang lebih tinggi menunjukkan situasi yang lebih baik.

Sebagai contoh, secara umum diterima bahwa pembelian oleh orang dalam perusahaan adalah indikator positif, sehingga perusahaan dengan lebih banyak pembelian oleh orang dalam akan mendapat peringkat lebih tinggi daripada perusahaan dengan lebih sedikit pembelian oleh orang dalam (atau bahkan penjualan oleh orang dalam).

Jumlah Bersih Pembelian oleh Orang Dalam (Peringkat)

-2 ( )

10394 out of 11305

Jumlah Bersih Pembelian oleh Orang Dalam adalah total jumlah orang dalam yang membeli dikurangi total jumlah orang dalam yang menjual dalam 90 hari terakhir. Peringkat persentil ditunjukkan di sini (kisaran dari 0 hingga 100%).

Persentase Saham yang Dibeli oleh Orang Dalam (Peringkat)

-0.020 %( )

10133 out of 11224

Persentase Saham yang Dibeli oleh Orang Dalam adalah total jumlah saham yang dibeli oleh orang dalam dikurangi total jumlah saham yang dijual oleh orang dalam dalam 90 hari terakhir, dibagi dengan total jumlah saham yang beredar dan dikalikan dengan 100.

Grafik Perdagangan Orang Dalam

Grafik berikut menunjukkan ACADIA Pharmaceuticals Inc. transaksi orang dalam. Orang dalam adalah pejabat, direktur, atau investor signifikan dalam suatu perusahaan. Secara umum, melakukan transaksi di perusahaan mereka berdasarkan informasi material yang belum dipublikasikan adalah ilegal bagi orang dalam. Ini tidak berarti bahwa mereka dilarang melakukan transaksi apa pun di perusahaan mereka sendiri. Namun, mereka wajib melaporkan semua transaksi kepada SEC melalui Formulir 4.

Daftar Orang Dalam dan Metrik Profitabilitas

Tabel ini menampilkan daftar orang dalam yang diketahui, dan dibuat secara otomatis dari pengajuan yang diungkapkan kepada SEC. Selain nama, jabatan terbaru, dan sebutan direktur, pejabat, atau pemilik 10%, kami memberikan kepemilikan terbaru yang diungkapkan. Selain itu, jika memungkinkan, kami memberikan kinerja perdagangan historis untuk orang dalam tersebut. Kinerja perdagangan historis adalah rata-rata tertimbang dari kinerja transaksi pembelian pasar terbuka aktual yang dilakukan oleh orang dalam tersebut. Untuk informasi lebih lanjut tentang bagaimana ini dihitung, tonton webinar YouTube ini.

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Orang Dalam Rata-rata Keuntungan (%) Saham
Dimiliki		 Terbagi
Disesuaikan
14159, L.p. Director, 10% Owner - [D] [10%] 71,647 71,647
667, L.p. Director, 10% Owner - [D] [10%] 38,452,877 39,365,965
Thomas H Aasen EXEC VP, CFO AND CBO - [O] 0 0
Baker Bros. Advisors Lp Director, 10% Owner - [D] [10%] 39,365,965 39,365,965
Felix Baker 10% Owner - [10%] 38,452,877 39,365,965
Julian Baker 10% Owner - [10%] 38,452,877 39,365,965
Jeffrey T Barnes 10% Owner - [10%] 236,500 3,160,238
Michael T Borer Director - [D] 0 0
Glenn Baity EVP AND GC - [O] 83,734 83,734
Baker Bros. Advisors (GP) LLC Director, 10% Owner - [D] [10%] 38,452,877 39,365,965
Baker Brothers Life Sciences LP Director, 10% Owner - [D] [10%] 38,452,877 39,365,965
Stephen R Biggar 0
Gordon M Binder 6,500
Laura Brege Director - [D] 15,095 15,095
Mark Carthy 10% Owner - [10%] 236,500 3,160,238
Stephen Davis CEO, Director - [D] [O] 186,555 186,555
James M Daly Director - [D] 34,041 34,041
Orang Dalam Rata-rata Keuntungan (%) Saham
Dimiliki		 Terbagi
Disesuaikan
Jonathan Fleming 10% Owner - [10%] 236,500 3,160,238
Garofalo Elizabeth A. Director - [D] 25,382 25,382
Carl L Gordon Director - [D] 774,006 774,006
Mary Ann Gray Director - [D] 149,476 149,476
Edmund Harrigan Director - [D] 35,041 35,041
Uli Hacksell CEO, Director - [D] [O] 115,549 115,549
Leslie L Iversen Director - [D] 36,127 36,127
Lester J Ph D Kaplan Director - [D] 17,000 17,000
Kim Austin D. EVP,General Counsel, Secretary - [O] 46,901 46,901
James Kihara PRINCIPAL ACCOUNTING OFFICER - [O] 20,395 20,395
Michael Lytton 10% Owner - [10%] 236,500 3,160,238
Mrna Fund Ii Lp 10% Owner - [10%] 236,500
Eric Alejandro Miller Controller & PAO - [O] 270 270
Roger Mills EVP, DEVELOPMENT AND CMO - [O] 18,550 18,550
Terrence O Moore EVP, CHIEF COMMERCIAL OFFICER - [O] 1,671 1,671
Nomura International Plc 10% Owner - [10%] 2,199,010 2,199,010
Adora Ndu Director - [D] 24,801 24,801
Orang Dalam Rata-rata Keuntungan (%) Saham
Dimiliki		 Terbagi
Disesuaikan
Nomura Phase4 Ventures GP LTD 10% Owner - [10%] 2,199,010 2,199,010
Nomura Phase4 Ventures LP 10% Owner - [10%] 2,199,010 2,199,010
Phase4 Ventures LTD Nomura 10% Owner - [10%] 2,199,010 2,199,010
Obp Management Iv Lp 10% Owner - [10%] 236,500 3,160,238
Oxford Bioscience Partners Iv Lp 10% Owner - [10%] 3,160,238 3,160,238
Torsten Rasmussen Director - [D] 8,500 8,500
Elena Ridloff EVP and CFO - [O] 10,553 10,553
Daniel B Soland Director - [D] 44,041 44,041
Schneyer Mark C. EVP, CHIEF FINANCIAL OFFICER - [O] 40,130 40,130
Stankovic Srdjan R. President - [O] 61,234 61,234
Brendan Teehan EVP, COO, HEAD OF COMMERCIAL - [O] 62,105 62,105
Bo-Ragnar Tolf 21,000
Alan G Walton Director, 10% Owner - [D] [10%] 8,833 3,160,238
William McDowall Wells Director - [D] 0 0
Yang Michael J. EVP and CCO - [O] 8,059 8,059
Young Todd S. 4,688
Osch Martien van Director - [D] 1,168,892 1,168,892

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Rekam Jejak Pembelian Orang Dalam - Analisis Keuntungan Jangka Pendek

Pada bagian ini, kami menganalisis profitabilitas setiap pembelian saham oleh orang dalam di pasar terbuka yang tidak direncanakan yang dilakukan di ACAD / ACADIA Pharmaceuticals Inc.. Analisis ini membantu memahami apakah orang dalam tersebut secara konsisten menghasilkan pengembalian abnormal, dan layak untuk diikuti. Analisis ini dilakukan selama satu tahun setelah setiap transaksi, dan hasilnya bersifat teoretis .

Tabel berikut menunjukkan pembelian pasar terbuka terbaru yang bukan bagian dari rencana perdagangan otomatis.

Tanggal Perdagangan Orang Dalam Dilaporkan
Saham		 Dilaporkan
Harga		 Disesuaikan
Saham		 Disesuaikan
Harga		 Dasar Biaya Hari-hari menuju
Maksimal		 Harga di
Maksimal		 Maksimal
Keuntungan ($)		 Maksimum Pengembalian (%)
2023-05-24 BAKER BROS. ADVISORS LP 20,304 25.2723 20,304 25.2723 513,129 54 33.4650 166,345 32.42
2023-05-24 BAKER BROS. ADVISORS LP 218,171 25.2723 218,171 25.2723 5,513,683
2023-05-24 BAKER BROS. ADVISORS LP 2,688 25.5138 2,688 25.5138 68,581
2023-05-24 BAKER BROS. ADVISORS LP 28,878 25.5138 28,878 25.5138 736,788
2023-05-24 BAKER BROS. ADVISORS LP 24,113 25.6500 24,113 25.6500 618,498
2023-05-24 BAKER BROS. ADVISORS LP 259,109 25.6500 259,109 25.6500 6,646,146
2023-05-23 BAKER BROS. ADVISORS LP 10,858 25.3302 10,858 25.3302 275,035
2023-05-23 BAKER BROS. ADVISORS LP 116,672 25.3302 116,672 25.3302 2,955,325
2023-05-23 BAKER BROS. ADVISORS LP 6,941 25.5400 6,941 25.5400 177,273

Harga yang Disesuaikan adalah harga yang disesuaikan dengan pemisahan saham. Ang Adjusted Shares ay ang jumlah saham yang disesuaikan dengan pemisahan saham (stock split).

ACAD / ACADIA Pharmaceuticals Inc. Insider Trades
Rekam Jejak Penjualan Orang Dalam - Analisis Kerugian Jangka Pendek

Dalam bagian ini, kami menganalisis penghindaran kerugian jangka pendek dari setiap penjualan dalam pasar terbuka yang tidak direncanakan oleh orang dalam yang dilakukan di ACAD / ACADIA Pharmaceuticals Inc.. Pola penghindaran kerugian yang konsisten dapat menunjukkan bahwa transaksi penjualan di masa mendatang dapat memprediksi penurunan harga. Analisis ini berlaku untuk satu tahun setelah setiap perdagangan, dan hasilnya bersifat teoretis .

Tabel berikut menunjukkan penjualan pasar terbuka terbaru yang bukan bagian dari rencana perdagangan otomatis.

Tanggal Perdagangan Orang Dalam Dilaporkan
Saham		 Dilaporkan
Harga		 Disesuaikan
Saham		 Disesuaikan
Harga		 Dasar Biaya Hari-hari menuju
Menit		 Harga di
Menit		 Kerugian Maksimal
Dihindari ($)		 Kerugian Maksimal
Dihindari (%)
2025-09-02 GAROFALO ELIZABETH A. 1,600 25.9753 1,600 25.9753 41,560 3 25.2600 -1,144 -2.75
2025-06-04 Brege Laura 14,446 21.7800 14,446 21.7800 314,634
2025-03-05 GAROFALO ELIZABETH A. 4,919 18.2300 4,919 18.2300 89,673
2024-01-08 DAVIS STEPHEN 3,732 29.9600 3,732 29.9600 111,811
2024-01-08 Teehan Brendan 731 29.9600 731 29.9600 21,901
2024-01-08 KIM AUSTIN D. 590 29.9600 590 29.9600 17,676
2023-11-20 Teehan Brendan 4,960 22.6400 4,960 22.6400 112,294
2023-11-20 Kihara James 1,985 22.6400 1,985 22.6400 44,940
2023-11-20 Schneyer Mark C. 5,108 22.6400 5,108 22.6400 115,645

Harga yang Disesuaikan adalah harga yang disesuaikan dengan pemisahan saham. Ang Adjusted Shares ay ang jumlah saham yang disesuaikan dengan pemisahan saham (stock split).

ACAD / ACADIA Pharmaceuticals Inc. Insider Trades
Riwayat Transaksi

Klik ikon tautan untuk melihat riwayat transaksi lengkap. Transaksi yang dilaporkan sebagai bagian dari rencana perdagangan otomatis 10b5-1 akan memiliki tanda X di kolom yang bertanda 10b-5.

Berkas
Tanggal		 Perdagangan
Tanggal		 Formulir Orang Dalam Ticker Judul Keamanan Kode 10b5-1 Langsung Latihan
Harga		 Satuan
Harga		 Unit
Diubah		 Nilai
Diubah (1 ribu)		 Sisa
Pilihan		 Sisa
Saham
2025-09-03 2025-09-02 4 GAROFALO ELIZABETH A. ACAD Common Stock S - Sale D 25.9753 -1,600 -42 25,382
2025-08-19 2025-08-18 4 Schneyer Mark C. ACAD Common Stock S - Sale D 25.1829 -22,000 -554 40,130
2025-06-05 2025-06-04 4 Brege Laura ACAD Common Stock S - Sale D 21.7800 -14,446 -315 15,095
2025-06-02 2025-05-29 4 Brege Laura ACAD Common Stock M - Exercise D 9,387 29,541
2025-06-02 2025-05-29 4 Daly James M ACAD Common Stock M - Exercise D 9,387 34,041
2025-06-02 2025-05-29 4 GAROFALO ELIZABETH A. ACAD Common Stock M - Exercise D 9,387 26,982
2025-06-02 2025-05-29 4 Ndu Adora ACAD Common Stock M - Exercise D 9,387 24,801
2025-06-02 2025-05-29 4 HARRIGAN EDMUND ACAD Common Stock M - Exercise D 9,387 35,041
2025-06-02 2025-05-29 4 SOLAND DANIEL B ACAD Common Stock M - Exercise D 9,387 44,041
2025-06-02 2025-05-29 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock A - Award I 16,214 39,365,965
2025-06-02 2025-05-29 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock A - Award I 16,214 39,365,965
2025-05-19 2025-05-16 4 Kihara James ACAD Common Stock S - Sale D 20.0000 -2,000 -40 20,395
2025-05-19 2025-05-16 4 Kihara James ACAD Common Stock S - Sale D 25.0000 -2,000 -50 22,395
2025-05-19 2025-05-16 4 Schneyer Mark C. ACAD Common Stock S - Sale D 25.0000 -2,000 -50 62,130
2025-05-02 2025-05-02 4 Kihara James ACAD Common Stock S - Sale D 14.6000 -1,327 -19 23,526
2025-05-02 2025-05-01 4 Kihara James ACAD Common Stock M - Exercise D 2,596 24,853
2025-05-02 2025-05-02 4 Schneyer Mark C. ACAD Common Stock S - Sale D 14.6000 -3,498 -51 62,773
2025-05-02 2025-05-01 4 Schneyer Mark C. ACAD Common Stock M - Exercise D 6,815 66,271
2025-04-08 2025-04-08 4 Schneyer Mark C. ACAD Common Stock S - Sale D 14.8200 -2,708 -40 59,456
2025-04-08 2025-04-05 4 Schneyer Mark C. ACAD Common Stock M - Exercise D 5,275 62,164
2025-04-08 2025-04-08 4 Kihara James ACAD Common Stock S - Sale D 14.8200 -1,028 -15 22,257
2025-04-08 2025-04-05 4 Kihara James ACAD Common Stock M - Exercise D 2,010 23,285
2025-03-26 2025-03-26 4 Kihara James ACAD Common Stock S - Sale D 17.0500 -1,095 -19 21,275
2025-03-26 2025-03-25 4 Kihara James ACAD Common Stock M - Exercise D 2,142 22,370
2025-03-26 2025-03-26 4 Schneyer Mark C. ACAD Common Stock S - Sale D 17.0500 -3,171 -54 56,889
2025-03-26 2025-03-25 4 Schneyer Mark C. ACAD Common Stock M - Exercise D 6,178 60,060
2025-03-06 2025-03-05 4 GAROFALO ELIZABETH A. ACAD Common Stock S - Sale D 18.2300 -4,919 -90 17,595
2025-02-25 2025-02-24 4 Kihara James ACAD Common Stock S - Sale D 19.9600 -475 -9 20,228
2025-02-25 2025-02-23 4 Kihara James ACAD Common Stock M - Exercise D 840 20,703
2025-02-25 2025-02-24 4 Schneyer Mark C. ACAD Common Stock S - Sale D 19.9600 -773 -15 53,882
2025-02-25 2025-02-23 4 Schneyer Mark C. ACAD Common Stock M - Exercise D 1,353 54,655
2024-11-19 2024-11-19 4 Teehan Brendan ACAD Common Stock S - Sale D 16.8100 -10,329 -174 62,105
2024-11-19 2024-11-17 4 Teehan Brendan ACAD Common Stock M - Exercise D 9,913 72,434
2024-11-19 2024-11-17 4 Teehan Brendan ACAD Common Stock M - Exercise D 9,913 72,434
2024-11-19 2024-11-19 4 Kihara James ACAD Common Stock S - Sale D 16.8100 -4,073 -68 19,863
2024-11-19 2024-11-17 4 Kihara James ACAD Common Stock M - Exercise D 3,965 23,936
2024-11-19 2024-11-17 4 Kihara James ACAD Common Stock M - Exercise D 3,965 23,936
2024-11-19 2024-11-19 4 Schneyer Mark C. ACAD Common Stock S - Sale D 16.8100 -10,259 -172 53,302
2024-11-19 2024-11-17 4 Schneyer Mark C. ACAD Common Stock M - Exercise D 9,913 63,561
2024-11-19 2024-11-17 4 Schneyer Mark C. ACAD Common Stock M - Exercise D 9,913 63,561
2024-10-15 2024-10-12 4 Ndu Adora ACAD Common Stock M - Exercise D 4,381 15,414
2024-08-20 2024-08-19 4 Schneyer Mark C. ACAD Common Stock S - Sale D 15.2800 -9,733 -149 43,735
2024-08-20 2024-08-16 4 Schneyer Mark C. ACAD Common Stock A - Award D 13,629 53,468
2024-08-20 2024-08-16 4 Schneyer Mark C. ACAD Common Stock A - Award D 5,275 39,839
2024-08-20 2024-08-19 4 Teehan Brendan ACAD Common Stock S - Sale D 15.2800 -9,534 -146 52,177
2024-08-20 2024-08-16 4 Teehan Brendan ACAD Common Stock A - Award D 13,629 61,711
2024-08-20 2024-08-16 4 Teehan Brendan ACAD Common Stock A - Award D 5,024 48,082
2024-08-20 2024-08-19 4 DAVIS STEPHEN ACAD Common Stock S - Sale D 15.2800 -31,747 -485 186,555
2024-08-20 2024-08-16 4 DAVIS STEPHEN ACAD Common Stock A - Award D 44,782 218,302
2024-08-20 2024-08-16 4 DAVIS STEPHEN ACAD Common Stock A - Award D 17,333 173,520
2024-06-11 2024-06-10 4 Schneyer Mark C. ACAD Common Stock S - Sale D 14.7900 -975 -14 34,564
2024-06-11 2024-06-08 4 Schneyer Mark C. ACAD Common Stock M - Exercise D 1,893 35,539
2024-05-31 2024-05-29 4 Brege Laura ACAD Common Stock M - Exercise D 6,652 20,154
2024-05-31 2024-05-29 4 SOLAND DANIEL B ACAD Common Stock M - Exercise D 6,652 34,654
2024-05-31 2024-05-29 4 HARRIGAN EDMUND ACAD Common Stock M - Exercise D 6,652 25,654
2024-05-31 2024-05-29 4 GAROFALO ELIZABETH A. ACAD Common Stock M - Exercise D 6,652 22,514
2024-05-31 2024-05-29 4 Daly James M ACAD Common Stock M - Exercise D 6,652 24,654
2024-05-31 2024-05-29 4 Ndu Adora ACAD Common Stock M - Exercise D 6,652 11,033
2024-05-31 2024-05-29 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock A - Award I 18,774 39,349,751
2024-05-31 2024-05-29 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock A - Award I 18,774 39,349,751
2024-05-03 2024-05-02 4 Kihara James ACAD Common Stock S - Sale D 16.9400 -1,326 -22 14,370
2024-05-03 2024-05-01 4 Kihara James ACAD Common Stock M - Exercise D 2,596 15,696
2024-05-03 2024-05-02 4 DAVIS STEPHEN ACAD Common Stock S - Sale D 16.9400 -11,427 -194 155,231
2024-05-03 2024-05-01 4 DAVIS STEPHEN ACAD Common Stock M - Exercise D 22,391 166,658
2024-05-03 2024-05-02 4 Teehan Brendan ACAD Common Stock S - Sale D 16.9400 -3,477 -59 42,133
2024-05-03 2024-05-01 4 Teehan Brendan ACAD Common Stock M - Exercise D 6,814 45,610
2024-05-03 2024-05-02 4 Schneyer Mark C. ACAD Common Stock S - Sale D 16.9400 -3,503 -59 32,053
2024-05-03 2024-05-01 4 Schneyer Mark C. ACAD Common Stock M - Exercise D 6,814 35,556
2024-04-09 2024-04-08 4 Kihara James ACAD Common Stock S - Sale D 17.8700 -762 -14 13,100
2024-04-09 2024-04-08 4 Kihara James ACAD Common Stock S - Sale D 17.8700 -1,028 -18 13,862
2024-04-09 2024-04-07 4 Kihara James ACAD Common Stock M - Exercise D 1,489 14,890
2024-04-09 2024-04-05 4 Kihara James ACAD Common Stock M - Exercise D 2,010 13,401
2024-04-09 2024-04-08 4 Schneyer Mark C. ACAD Common Stock S - Sale D 17.8700 -2,716 -49 28,742
2024-04-09 2024-04-05 4 Schneyer Mark C. ACAD Common Stock M - Exercise D 5,275 31,458
2024-04-09 2024-04-08 4 DAVIS STEPHEN ACAD Common Stock S - Sale D 17.8700 -17,716 -317 144,267
2024-04-09 2024-04-08 4 DAVIS STEPHEN ACAD Common Stock S - Sale D 17.8700 -8,858 -158 161,983
2024-04-09 2024-04-05 4 DAVIS STEPHEN ACAD Common Stock M - Exercise D 34,666 170,841
2024-04-09 2024-04-05 4 DAVIS STEPHEN ACAD Common Stock M - Exercise D 17,333 136,175
2024-04-09 2024-04-08 4 Teehan Brendan ACAD Common Stock S - Sale D 17.8700 -2,568 -46 38,796
2024-04-09 2024-04-05 4 Teehan Brendan ACAD Common Stock M - Exercise D 5,024 41,364
2024-03-27 2024-03-27 4 Teehan Brendan ACAD Common Stock S - Sale D 17.9000 -5,140 -92 36,340
2024-03-27 2024-03-25 4 Teehan Brendan ACAD Common Stock A - Award D 10,048 41,480
2024-03-27 2024-03-27 4 DAVIS STEPHEN ACAD Common Stock S - Sale D 17.9000 -17,714 -317 118,842
2024-03-27 2024-03-25 4 DAVIS STEPHEN ACAD Common Stock A - Award D 34,666 136,556
2024-03-27 2024-03-27 4 Schneyer Mark C. ACAD Common Stock S - Sale D 17.9000 -5,434 -97 26,183
2024-03-27 2024-03-25 4 Schneyer Mark C. ACAD Common Stock A - Award D 10,550 31,617
2024-02-27 2024-02-26 4 Schneyer Mark C. ACAD Common Stock S - Sale D 24.6700 -772 -19 21,067
2024-02-27 2024-02-23 4 Schneyer Mark C. ACAD Common Stock M - Exercise D 1,353 21,839
2024-02-27 2024-02-26 4 Teehan Brendan ACAD Common Stock S - Sale D 24.6700 -624 -15 31,432
2024-02-27 2024-02-23 4 Teehan Brendan ACAD Common Stock M - Exercise D 1,107 32,056
2024-02-27 2024-02-26 4 Kihara James ACAD Common Stock S - Sale D 24.6700 -474 -12 11,391
2024-02-27 2024-02-23 4 Kihara James ACAD Common Stock M - Exercise D 840 11,865
2024-02-27 2024-02-26 4 DAVIS STEPHEN ACAD Common Stock S - Sale D 24.6700 -5,577 -138 101,890
2024-02-27 2024-02-23 4 DAVIS STEPHEN ACAD Common Stock M - Exercise D 10,946 107,467
2024-01-09 2024-01-08 4 KIM AUSTIN D. ACAD Common Stock S - Sale D 29.9600 -590 -18 46,901
2024-01-09 2024-01-06 4 KIM AUSTIN D. ACAD Common Stock M - Exercise D 1,634 47,491
2024-01-09 2024-01-08 4 Teehan Brendan ACAD Common Stock S - Sale D 29.9600 -731 -22 30,949
2024-01-09 2024-01-06 4 Teehan Brendan ACAD Common Stock M - Exercise D 1,287 31,680
2024-01-09 2024-01-08 4 DAVIS STEPHEN ACAD Common Stock S - Sale D 29.9600 -3,732 -112 96,521
2024-01-09 2024-01-06 4 DAVIS STEPHEN ACAD Common Stock M - Exercise D 9,528 100,253
2023-12-15 2023-12-15 4 Kihara James ACAD Common Stock S - Sale D 28.3000 -2,000 -57 11,025
2023-11-28 2023-11-24 4 GAROFALO ELIZABETH A. ACAD Common Stock G - Gift D -2,918 15,862
2023-11-21 2023-11-20 4 Kihara James ACAD Common Stock S - Sale D 22.6400 -1,985 -45 13,025
2023-11-21 2023-11-17 4 Kihara James ACAD Common Stock M - Exercise D 1,982 15,010
2023-11-21 2023-11-17 4 Kihara James ACAD Common Stock M - Exercise D 1,982 15,010
2023-11-21 2023-11-20 4 Teehan Brendan ACAD Common Stock S - Sale D 22.6400 -4,960 -112 30,393
2023-11-21 2023-11-17 4 Teehan Brendan ACAD Common Stock M - Exercise D 4,956 35,353
2023-11-21 2023-11-17 4 Teehan Brendan ACAD Common Stock M - Exercise D 4,956 35,353
2023-11-21 2023-11-20 4 Schneyer Mark C. ACAD Common Stock S - Sale D 22.6400 -5,108 -116 20,486
2023-11-21 2023-11-17 4 Schneyer Mark C. ACAD Common Stock M - Exercise D 4,956 25,594
2023-11-21 2023-11-17 4 Schneyer Mark C. ACAD Common Stock M - Exercise D 4,956 25,594
2023-10-16 2023-10-12 4 Ndu Adora ACAD Common Stock M - Exercise D 4,381 4,381
2023-10-06 2023-10-06 4 DAVIS STEPHEN ACAD Common Stock S - Sale D 21.9600 -51,563 -1,132 89,131
2023-10-06 2023-10-05 4 DAVIS STEPHEN ACAD Common Stock M - Exercise D 103,999 140,694
2023-10-06 2023-10-06 4 KIM AUSTIN D. ACAD Common Stock S - Sale D 21.9600 -16,369 -359 45,857
2023-10-06 2023-10-05 4 KIM AUSTIN D. ACAD Common Stock M - Exercise D 36,174 62,226
2023-09-19 2023-09-15 4 Kihara James ACAD Common Stock S - Sale D 25.8800 -2,000 -52 10,778
2023-08-23 2023-08-21 4 Schneyer Mark C. ACAD Common Stock S - Sale D 28.9970 -10,000 -290 15,682
2023-07-18 2023-07-14 4 DAVIS STEPHEN ACAD Common Stock S - Sale D 30.0435 -100,000 -3,004 36,695
2023-07-18 2023-07-14 4 DAVIS STEPHEN ACAD Common Stock M - Exercise D 20.7700 100,000 2,077 136,695
2023-07-13 2023-07-12 4 DAVIS STEPHEN ACAD Common Stock S - Sale D 25.0517 -55,104 -1,380 36,695
2023-07-13 2023-07-11 4 DAVIS STEPHEN ACAD Common Stock S - Sale D 25.0000 -16,498 -412 91,799
2023-06-16 2023-06-15 4 Kihara James ACAD Common Stock S - Sale D 24.1500 -2,000 -48 9,144
2023-06-14 2023-06-12 4 Brege Laura ACAD Common Stock S - Sale D 24.8680 -4,500 -112 13,502
2023-06-12 2023-06-08 4 Schneyer Mark C. ACAD Common Stock S - Sale D 25.0200 -974 -24 22,824
2023-06-12 2023-06-08 4 Schneyer Mark C. ACAD Common Stock M - Exercise D 1,893 23,798
2023-06-05 2023-06-01 4 SOLAND DANIEL B ACAD Common Stock M - Exercise D 8,552 28,002
2023-06-05 2022-06-07 4 SOLAND DANIEL B ACAD Common Stock M - Exercise D 6,391 19,450
2023-06-05 2021-06-22 4 SOLAND DANIEL B ACAD Common Stock M - Exercise D 3,059 13,059
2023-06-05 2023-06-01 4 Brege Laura ACAD Common Stock M - Exercise D 8,552 18,002
2023-06-05 2022-06-07 4 Brege Laura ACAD Common Stock M - Exercise D 6,391 9,450
2023-06-05 2021-06-22 4 Brege Laura ACAD Common Stock M - Exercise D 3,059 3,059
2023-06-05 2023-06-01 4 HARRIGAN EDMUND ACAD Common Stock M - Exercise D 8,552 19,002
2023-06-05 2022-06-07 4 HARRIGAN EDMUND ACAD Common Stock M - Exercise D 6,391 10,450
2023-06-05 2021-06-22 4 HARRIGAN EDMUND ACAD Common Stock M - Exercise D 3,059 4,059
2023-06-05 2023-06-01 4 Daly James M ACAD Common Stock M - Exercise D 8,552 18,002
2023-06-05 2022-06-07 4 Daly James M ACAD Common Stock M - Exercise D 6,391 9,450
2023-06-05 2021-06-22 4 Daly James M ACAD Common Stock M - Exercise D 3,059 3,059
2023-06-05 2023-06-01 4 GAROFALO ELIZABETH A. ACAD Common Stock M - Exercise D 8,552 18,780
2023-06-05 2022-09-29 4 GAROFALO ELIZABETH A. ACAD Common Stock M - Exercise D 1,919 10,228
2023-06-05 2022-06-07 4 GAROFALO ELIZABETH A. ACAD Common Stock M - Exercise D 6,391 8,309
2023-06-05 2023-06-01 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock A - Award I 13,304 39,330,977
2023-06-05 2023-06-01 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock A - Award I 13,304 39,330,977
2023-05-24 2023-05-24 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 25.6500 259,109 6,646 39,317,673
2023-05-24 2023-05-24 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 25.6500 24,113 618 3,610,443
2023-05-24 2023-05-24 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 25.5138 28,878 737 39,058,564
2023-05-24 2023-05-24 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 25.5138 2,688 69 3,586,330
2023-05-24 2023-05-24 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 25.2723 218,171 5,514 39,029,686
2023-05-24 2023-05-24 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 25.2723 20,304 513 3,583,642
2023-05-24 2023-05-23 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 25.5400 74,582 1,905 38,811,515
2023-05-24 2023-05-23 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 25.5400 6,941 177 3,563,338
2023-05-24 2023-05-23 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 25.3302 116,672 2,955 38,736,933
2023-05-24 2023-05-23 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 25.3302 10,858 275 3,556,397
2023-05-24 2023-05-23 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock M - Exercise I 17.0100 12,500 213 38,620,261
2023-05-24 2023-05-23 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock M - Exercise I 17.0100 12,500 213 38,620,261
2023-05-24 2023-05-22 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 24.8000 40,632 1,008 38,607,761
2023-05-24 2023-05-22 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 24.8000 3,781 94 3,533,039
2023-05-24 2023-05-22 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 24.4604 82,148 2,009 38,567,129
2023-05-24 2023-05-22 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 24.4604 7,645 187 3,529,258
2023-05-19 2023-05-17 4 Kihara James ACAD Common Stock S - Sale D 22.5000 -5,947 -134 11,144
2023-05-19 2023-05-17 4 Kihara James ACAD Common Stock M - Exercise D 5,947 17,091
2023-05-19 2023-05-17 4 Kihara James ACAD Common Stock M - Exercise D 5,947 17,091
2023-05-19 2023-05-17 4 Schneyer Mark C. ACAD Common Stock S - Sale D 22.5000 -15,310 -344 21,905
2023-05-19 2023-05-17 4 Schneyer Mark C. ACAD Common Stock M - Exercise D 14,869 37,215
2023-05-19 2023-05-17 4 Schneyer Mark C. ACAD Common Stock M - Exercise D 14,869 37,215
2023-05-19 2023-05-17 4 Teehan Brendan ACAD Common Stock S - Sale D 22.5000 -14,869 -335 24,356
2023-05-19 2023-05-17 4 Teehan Brendan ACAD Common Stock M - Exercise D 14,869 39,225
2023-05-19 2023-05-17 4 Teehan Brendan ACAD Common Stock M - Exercise D 14,869 39,225
2023-05-02 2023-05-01 4 KIM AUSTIN D. ACAD Common Stock S - Sale D 21.1800 -917 -19 25,513
2023-05-02 2023-04-29 4 KIM AUSTIN D. ACAD Common Stock M - Exercise D 3,005 26,430
2023-05-02 2023-05-01 4 Teehan Brendan ACAD Common Stock S - Sale D 21.1800 -548 -12 9,487
2023-05-02 2023-04-29 4 Teehan Brendan ACAD Common Stock M - Exercise D 1,567 10,035
2023-05-02 2023-05-01 4 DAVIS STEPHEN ACAD Common Stock S - Sale D 21.1800 -7,806 -165 108,297
2023-05-02 2023-04-29 4 DAVIS STEPHEN ACAD Common Stock M - Exercise D 15,625 116,103
2023-04-11 2023-04-10 4 Kihara James ACAD Common Stock S - Sale D 18.1400 -523 -9 5,197
2023-04-11 2023-04-07 4 Kihara James ACAD Common Stock M - Exercise D 1,489 5,720
2023-04-07 2023-04-06 4 Teehan Brendan ACAD Common Stock S - Sale D 18.1600 -1,751 -32 8,468
2023-04-07 2023-04-05 4 Teehan Brendan ACAD Common Stock M - Exercise D 5,024 10,219
2023-04-07 2023-04-06 4 Kihara James ACAD Common Stock S - Sale D 18.1600 -701 -13 4,231
2023-04-07 2023-04-05 4 Kihara James ACAD Common Stock M - Exercise D 2,009 4,932
2023-04-07 2023-04-06 4 Schneyer Mark C. ACAD Common Stock S - Sale D 18.1600 -1,916 -35 7,477
2023-04-07 2023-04-05 4 Schneyer Mark C. ACAD Common Stock M - Exercise D 5,275 9,393
2023-04-07 2023-04-06 4 DAVIS STEPHEN ACAD Common Stock S - Sale D 18.1600 -8,582 -156 100,478
2023-04-07 2023-04-05 4 DAVIS STEPHEN ACAD Common Stock M - Exercise D 17,333 109,060
2023-04-07 2023-04-06 4 KIM AUSTIN D. ACAD Common Stock S - Sale D 18.1600 -1,456 -26 23,425
2023-04-07 2023-04-05 4 KIM AUSTIN D. ACAD Common Stock M - Exercise D 4,773 24,881
2023-02-27 2023-02-24 4 DAVIS STEPHEN ACAD Common Stock S - Sale D 18.7800 -3,851 -72 91,727
2023-02-27 2023-02-23 4 DAVIS STEPHEN ACAD Common Stock M - Exercise D 10,945 95,578
2023-02-27 2023-02-24 4 Schneyer Mark C. ACAD Common Stock S - Sale D 18.7800 -577 -11 4,118
2023-02-27 2023-02-23 4 Schneyer Mark C. ACAD Common Stock M - Exercise D 1,353 4,695
2023-02-27 2023-02-24 4 Teehan Brendan ACAD Common Stock S - Sale D 18.7800 -461 -9 5,195
2023-02-27 2023-02-23 4 Teehan Brendan ACAD Common Stock M - Exercise D 1,107 5,656
2023-02-27 2023-02-24 4 KIM AUSTIN D. ACAD Common Stock S - Sale D 18.7800 -803 -15 20,108
2023-02-27 2023-02-23 4 KIM AUSTIN D. ACAD Common Stock M - Exercise D 2,214 20,911
2023-02-27 2023-02-24 4 Kihara James ACAD Common Stock S - Sale D 18.7800 -350 -7 2,923
2023-02-27 2023-02-23 4 Kihara James ACAD Common Stock M - Exercise D 840 3,273
2023-01-17 2023-01-12 4 Brege Laura ACAD Common Stock S - Sale D 18.2500 -12,500 -228 0
2023-01-17 2023-01-12 4 Brege Laura ACAD Common Stock M - Exercise D 17.0100 12,500 213 12,500
2023-01-17 2023-01-12 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock M - Exercise I 5.2200 15,000 78 38,484,981
2023-01-17 2023-01-12 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock M - Exercise I 5.2200 15,000 78 38,484,981
2023-01-10 2023-01-09 4 DAVIS STEPHEN ACAD Common Stock S - Sale D 17.1303 -3,904 -67 84,633
2023-01-10 2023-01-06 4 DAVIS STEPHEN ACAD Common Stock M - Exercise D 9,528 88,537
2023-01-10 2023-01-09 4 Teehan Brendan ACAD Common Stock S - Sale D 17.1303 -532 -9 4,549
2023-01-10 2023-01-06 4 Teehan Brendan ACAD Common Stock M - Exercise D 1,286 5,081
2023-01-10 2023-01-09 4 KIM AUSTIN D. ACAD Common Stock S - Sale D 17.1303 -589 -10 18,697
2023-01-10 2023-01-06 4 KIM AUSTIN D. ACAD Common Stock M - Exercise D 1,633 19,286
2022-11-22 2022-11-21 4 Stankovic Srdjan R. ACAD Common Stock S - Sale D 15.0700 -1,847 -28 61,234
2022-11-22 2022-11-19 4 Stankovic Srdjan R. ACAD Common Stock M - Exercise D 6,250 63,081
2022-10-18 2022-10-15 4 Stankovic Srdjan R. ACAD Common Stock S - Sale D 15.8100 -1,326 -21 56,831
2022-10-18 2022-10-15 4 Stankovic Srdjan R. ACAD Common Stock M - Exercise D 2,969 58,157
2022-10-18 2022-10-15 4 DAVIS STEPHEN ACAD Common Stock S - Sale D 15.8100 -2,804 -44 79,009
2022-10-18 2022-10-15 4 DAVIS STEPHEN ACAD Common Stock M - Exercise D 5,938 81,813
2022-06-10 2022-06-09 4 Schneyer Mark C. ACAD Common Stock S - Sale D 17.9095 -653 -12 3,342
2022-06-10 2022-06-08 4 Schneyer Mark C. ACAD Common Stock M - Exercise D 1,893 3,995
2022-06-09 2022-06-07 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock A - Award I 17,104 38,469,981
2022-06-09 2022-06-07 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock A - Award I 17,104 38,469,981
2022-05-03 2022-05-02 4 DAVIS STEPHEN ACAD Common Stock S - Sale D 18.1819 -5,483 -100 75,875
2022-05-03 2022-04-29 4 DAVIS STEPHEN ACAD Restricted Stock Units M - Exercise D -15,625 15,625
2022-05-03 2022-04-29 4 DAVIS STEPHEN ACAD Common Stock M - Exercise D 15,625 81,358
2022-05-03 2022-05-02 4 Stankovic Srdjan R. ACAD Common Stock S - Sale D 18.1818 -2,865 -52 55,188
2022-05-03 2022-04-29 4 Stankovic Srdjan R. ACAD Restricted Stock Units M - Exercise D -9,616 9,616
2022-05-03 2022-04-29 4 Stankovic Srdjan R. ACAD Common Stock M - Exercise D 9,616 58,053
2022-05-03 2022-05-02 4 KIM AUSTIN D. ACAD Common Stock S - Sale D 18.1820 -894 -16 16,742
2022-05-03 2022-04-29 4 KIM AUSTIN D. ACAD Restricted Stock Units M - Exercise D -3,005 3,005
2022-05-03 2022-04-29 4 KIM AUSTIN D. ACAD Common Stock M - Exercise D 3,005 17,636
2022-05-03 2022-05-02 4 Teehan Brendan ACAD Common Stock S - Sale D 18.1820 -552 -10 3,437
2022-05-03 2022-04-29 4 Teehan Brendan ACAD Restricted Stock Units M - Exercise D -1,567 1,567
2022-05-03 2022-04-29 4 Teehan Brendan ACAD Common Stock M - Exercise D 1,567 3,989
2022-04-11 2022-04-08 4 Kihara James ACAD Common Stock S - Sale D 27.0500 -1,025 -28 2,433
2022-04-11 2022-04-07 4 Kihara James ACAD Restricted Stock Units M - Exercise D -2,977 2,978
2022-04-11 2022-04-07 4 Kihara James ACAD Common Stock M - Exercise D 2,977 3,458
2022-04-07 2022-04-05 4 Kihara James ACAD Restricted Stock Units A - Award D 8,039 8,039
2022-04-07 2022-04-05 4 Kihara James ACAD Stock Options (Right to Buy) A - Award D 25.75 13,793 13,793
2022-04-07 2022-04-05 4 Teehan Brendan ACAD Restricted Stock Units A - Award D 20,096 20,096
2022-04-07 2022-04-05 4 Teehan Brendan ACAD Stock Options (Right to Buy) A - Award D 25.75 68,966 68,966
2022-04-07 2022-04-05 4 Schneyer Mark C. ACAD Restricted Stock Units A - Award D 21,101 21,101
2022-04-07 2022-04-05 4 Schneyer Mark C. ACAD Stock Options (Right to Buy) A - Award D 25.75 72,414 72,414
2022-04-07 2022-04-05 4 KIM AUSTIN D. ACAD Restricted Stock Units A - Award D 96,463 96,463
2022-04-07 2022-04-05 4 KIM AUSTIN D. ACAD Restricted Stock Units A - Award D 19,092 19,092
2022-04-07 2022-04-05 4 KIM AUSTIN D. ACAD Stock Options (Right to Buy) A - Award D 25.75 65,517 65,517
2022-04-07 2022-04-05 4 Stankovic Srdjan R. ACAD Restricted Stock Units A - Award D 144,695 144,695
2022-04-07 2022-04-05 4 Stankovic Srdjan R. ACAD Restricted Stock Units A - Award D 36,174 36,174
2022-04-07 2022-04-05 4 Stankovic Srdjan R. ACAD Stock Options (Right to Buy) A - Award D 25.75 124,138 124,138
2022-04-07 2022-04-05 4 DAVIS STEPHEN ACAD Restricted Stock Units A - Award D 277,331 277,331
2022-04-07 2022-04-05 4 DAVIS STEPHEN ACAD Restricted Stock Units A - Award D 69,333 69,333
2022-04-07 2022-04-05 4 DAVIS STEPHEN ACAD Stock Options (Right to Buy) A - Award D 25.75 237,931 237,931
2022-02-25 2022-02-23 4 Schneyer Mark C. ACAD Restricted Stock Units M - Exercise D 1,352 4,059
2022-02-25 2022-02-23 4 Schneyer Mark C. ACAD Common Stock S - Sale D 23.8000 -553 -13 2,102
2022-02-25 2022-02-23 4 Schneyer Mark C. ACAD Common Stock M - Exercise D 1,352 2,655
2022-02-25 2022-02-23 4 KIM AUSTIN D. ACAD Restricted Stock Units M - Exercise D 2,213 6,642
2022-02-25 2022-02-23 4 KIM AUSTIN D. ACAD Common Stock S - Sale D 23.8000 -782 -19 14,631
2022-02-25 2022-02-23 4 KIM AUSTIN D. ACAD Common Stock M - Exercise D 2,213 15,413
2022-02-25 2022-02-23 4 Teehan Brendan ACAD Restricted Stock Units M - Exercise D 1,106 3,321
2022-02-25 2022-02-23 4 Teehan Brendan ACAD Common Stock S - Sale D 23.8000 -472 -11 2,422
2022-02-25 2022-02-23 4 Teehan Brendan ACAD Common Stock M - Exercise D 1,106 2,894
2022-02-25 2022-02-23 4 DAVIS STEPHEN ACAD Restricted Stock Units M - Exercise D 10,945 32,837
2022-02-25 2022-02-23 4 DAVIS STEPHEN ACAD Common Stock S - Sale D 23.8000 -3,928 -93 65,733
2022-02-25 2022-02-23 4 DAVIS STEPHEN ACAD Common Stock M - Exercise D 10,945 69,661
2022-02-25 2022-02-23 4 Kihara James ACAD Restricted Stock Units M - Exercise D 840 2,520
2022-02-25 2022-02-23 4 Kihara James ACAD Common Stock S - Sale D 23.8000 -359 -9 481
2022-02-25 2022-02-23 4 Kihara James ACAD Common Stock M - Exercise D 840 840
2022-02-25 2022-02-23 4 Stankovic Srdjan R. ACAD Restricted Stock Units M - Exercise D 4,919 14,758
2022-02-25 2022-02-23 4 Stankovic Srdjan R. ACAD Common Stock S - Sale D 23.8000 -1,501 -36 48,437
2022-02-25 2022-02-23 4 Stankovic Srdjan R. ACAD Common Stock M - Exercise D 4,919 49,938
2022-01-10 2022-01-06 4 DAVIS STEPHEN ACAD Restricted Stock Units M - Exercise D -9,527 19,056
2022-01-10 2022-01-06 4 DAVIS STEPHEN ACAD Common Stock S - Sale D 23.0500 -3,718 -86 58,716
2022-01-10 2022-01-06 4 DAVIS STEPHEN ACAD Common Stock M - Exercise D 9,527 62,434
2022-01-10 2022-01-06 4 KIM AUSTIN D. ACAD Restricted Stock Units M - Exercise D -1,633 3,267
2022-01-10 2022-01-06 4 KIM AUSTIN D. ACAD Common Stock S - Sale D 23.0500 -574 -13 13,200
2022-01-10 2022-01-06 4 KIM AUSTIN D. ACAD Common Stock M - Exercise D 1,633 13,774
2022-01-10 2022-01-06 4 Stankovic Srdjan R. ACAD Restricted Stock Units M - Exercise D -5,444 10,889
2022-01-10 2022-01-06 4 Stankovic Srdjan R. ACAD Common Stock S - Sale D 23.0500 -1,937 -45 45,019
2022-01-10 2022-01-06 4 Stankovic Srdjan R. ACAD Common Stock M - Exercise D 5,444 46,956
2022-01-10 2022-01-06 4 Teehan Brendan ACAD Restricted Stock Units M - Exercise D -1,286 2,573
2022-01-10 2022-01-06 4 Teehan Brendan ACAD Common Stock S - Sale D 23.0500 -538 -12 1,788
2022-01-10 2022-01-06 4 Teehan Brendan ACAD Common Stock M - Exercise D 1,286 2,326
2021-12-20 3 Schneyer Mark C. ACAD Common Stock D 1,303
2021-11-23 2021-11-22 4 Stankovic Srdjan R. ACAD Common Stock S - Sale D 19.0100 -2,803 -53 41,512
2021-11-23 2021-11-19 4 Stankovic Srdjan R. ACAD Restricted Stock Units M - Exercise D -6,250 6,250
2021-11-23 2021-11-19 4 Stankovic Srdjan R. ACAD Common Stock M - Exercise D 6,250 44,315
2021-11-19 2021-11-17 4 Kihara James ACAD Restricted Stock Units A - Award D 15,860 15,860
2021-11-19 2021-11-17 4 Kihara James ACAD Restricted Stock Units A - Award D 15,860 15,860
2021-11-19 2021-11-17 4 Teehan Brendan ACAD Restricted Stock Units A - Award D 39,651 39,651
2021-11-19 2021-11-17 4 Teehan Brendan ACAD Restricted Stock Units A - Award D 39,651 39,651
2021-11-05 3 Teehan Brendan ACAD Common Stock D 807
2021-10-19 2021-10-18 4 Stankovic Srdjan R. ACAD Common Stock S - Sale D 17.4100 -1,338 -23 38,065
2021-10-19 2021-10-15 4 Stankovic Srdjan R. ACAD Restricted Stock Units M - Exercise D -2,969 2,969
2021-10-19 2021-10-15 4 Stankovic Srdjan R. ACAD Common Stock M - Exercise D 2,969 39,403
2021-10-19 2021-10-18 4 DAVIS STEPHEN ACAD Common Stock S - Sale D 17.4100 -2,963 -52 52,906
2021-10-19 2021-10-15 4 DAVIS STEPHEN ACAD Restricted Stock Units M - Exercise D -5,938 5,938
2021-10-19 2021-10-15 4 DAVIS STEPHEN ACAD Common Stock M - Exercise D 5,938 55,869
2021-10-01 2021-09-29 4 GAROFALO ELIZABETH A. ACAD Restricted Stock Units M - Exercise D 1,918 1,919
2021-10-01 2021-09-29 4 GAROFALO ELIZABETH A. ACAD Common Stock M - Exercise D 1,918 1,918
2021-06-24 2021-06-22 4 SOLAND DANIEL B ACAD Restricted Stock Units A - Award D 6,391 6,391
2021-06-24 2021-06-22 4 SOLAND DANIEL B ACAD Director Stock Options (Right to Buy) A - Award D 24.88 11,637 11,637
2021-06-24 2021-06-22 4 GAROFALO ELIZABETH A. ACAD Restricted Stock Units A - Award D 6,391 6,391
2021-06-24 2021-06-22 4 GAROFALO ELIZABETH A. ACAD Director Stock Options (Right to Buy) A - Award D 24.88 11,637 11,637
2021-06-24 2021-06-22 4 HARRIGAN EDMUND ACAD Restricted Stock Units A - Award D 6,391 6,391
2021-06-24 2021-06-22 4 HARRIGAN EDMUND ACAD Director Stock Options (Right to Buy) A - Award D 24.88 11,637 11,637
2021-06-24 2021-06-22 4 Daly James M ACAD Restricted Stock Units A - Award D 6,391 6,391
2021-06-24 2021-06-22 4 Daly James M ACAD Director Stock Options (Right to Buy) A - Award D 24.88 11,637 11,637
2021-06-24 2021-06-22 4 Brege Laura ACAD Restricted Stock Units A - Award D 6,391 6,391
2021-06-24 2021-06-22 4 Brege Laura ACAD Director Stock Options (Right to Buy) A - Award D 24.88 11,637 11,637
2021-06-24 2021-06-22 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Non-Qualified Stock Options (right to buy) A - Award I 24.88 23,274 23,274
2021-06-24 2021-06-22 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock A - Award I 12,782 38,452,877
2021-06-24 2021-06-22 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock A - Award I 12,782 38,452,877
2021-04-30 2021-04-30 4 Ridloff Elena ACAD Common Stock S - Sale D 20.3300 -1,032 -21 10,553
2021-04-30 2021-04-29 4 Ridloff Elena ACAD Restricted Stock Units M - Exercise D -3,245 6,491
2021-04-30 2021-04-29 4 Ridloff Elena ACAD Common Stock M - Exercise D 3,245 11,585
2021-04-30 2021-04-30 4 KIM AUSTIN D. ACAD Common Stock S - Sale D 20.3300 -1,054 -21 11,371
2021-04-30 2021-04-29 4 KIM AUSTIN D. ACAD Restricted Stock Units M - Exercise D -3,005 6,010
2021-04-30 2021-04-29 4 KIM AUSTIN D. ACAD Common Stock M - Exercise D 3,005 12,425
2021-04-30 2021-04-30 4 DAVIS STEPHEN ACAD Common Stock S - Sale D 20.3300 -7,850 -160 49,312
2021-04-30 2021-04-29 4 DAVIS STEPHEN ACAD Restricted Stock Units M - Exercise D -15,625 31,250
2021-04-30 2021-04-29 4 DAVIS STEPHEN ACAD Common Stock M - Exercise D 15,625 57,162
2021-04-30 2021-04-30 4 Stankovic Srdjan R. ACAD Common Stock S - Sale D 20.3300 -4,230 -86 36,434
2021-04-30 2021-04-29 4 Stankovic Srdjan R. ACAD Restricted Stock Units M - Exercise D -9,615 19,232
2021-04-30 2021-04-29 4 Stankovic Srdjan R. ACAD Common Stock M - Exercise D 9,615 40,664
2021-02-25 2021-02-23 4 Stankovic Srdjan R. ACAD Restricted Stock Units A - Award D 19,677 19,677
2021-02-25 2021-02-23 4 Stankovic Srdjan R. ACAD Stock Options (Right to Buy) A - Award D 49.74 72,463 72,463
2021-02-25 2021-02-23 4 Kihara James ACAD Restricted Stock Units A - Award D 3,360 3,360
2021-02-25 2021-02-23 4 Kihara James ACAD Stock Options (Right to Buy) A - Award D 49.74 6,187 6,187
2021-02-25 2021-02-23 4 Ridloff Elena ACAD Restricted Stock Units A - Award D 9,839 9,839
2021-02-25 2021-02-23 4 Ridloff Elena ACAD Stock Options (Right to Buy) A - Award D 49.74 36,231 36,231
2021-02-25 2021-02-23 4 KIM AUSTIN D. ACAD Restricted Stock Units A - Award D 8,855 8,855
2021-02-25 2021-02-23 4 KIM AUSTIN D. ACAD Stock Options (Right to Buy) A - Award D 49.74 32,608 32,608
2021-02-25 2021-02-23 4 DAVIS STEPHEN ACAD Restricted Stock Units A - Award D 43,782 43,782
2021-02-25 2021-02-23 4 DAVIS STEPHEN ACAD Stock Options (Right to Buy) A - Award D 49.74 161,230 161,230
2021-02-08 2021-02-04 4 DAVIS STEPHEN ACAD Employee Stock Options (Right to Buy) A - Award D 21.28 23,750 23,750
2021-02-08 2021-02-04 4 DAVIS STEPHEN ACAD Employee Stock Options (Right to Buy) A - Award D 29.59 40,625 40,625
2021-02-08 2021-02-04 4 DAVIS STEPHEN ACAD Employee Stock Options (Right to Buy) A - Award D 35.80 40,625 40,625
2021-02-08 2021-02-04 4 DAVIS STEPHEN ACAD Common Stock S - Sale D 50.6100 -14,195 -718 28,900
2021-02-08 2021-02-04 4 DAVIS STEPHEN ACAD Common Stock A - Award D 31,250 43,059
2021-02-08 2021-02-04 4 Ridloff Elena ACAD Common Stock S - Sale D 50.6100 -2,051 -104 8,340
2021-02-08 2021-02-04 4 Ridloff Elena ACAD Common Stock A - Award D 6,490 10,391
2021-02-08 2021-02-04 4 Stankovic Srdjan R. ACAD Employee Stock Option (Right to Buy) A - Award D 21.28 11,875 11,875
2021-02-08 2021-02-04 4 Stankovic Srdjan R. ACAD Employee Stock Option (Right to Buy) A - Award D 35.80 21,875 21,875
2021-02-08 2021-02-04 4 Stankovic Srdjan R. ACAD Employee Stock Option (Right to Buy) A - Award D 29.59 15,625 15,625
2021-02-08 2021-02-04 4 Stankovic Srdjan R. ACAD Common Stock S - Sale D 50.6100 -8,429 -427 31,049
2021-02-08 2021-02-04 4 Stankovic Srdjan R. ACAD Common Stock A - Award D 19,231 39,478
2021-02-08 2021-02-04 4 KIM AUSTIN D. ACAD Common Stock S - Sale D 50.6100 -2,107 -107 9,911
2021-02-08 2021-02-04 4 KIM AUSTIN D. ACAD Common Stock A - Award D 6,009 12,018
2021-01-14 2021-01-12 4 Stankovic Srdjan R. ACAD Stock Option (Right to Buy) M - Exercise D 18.12 -700 89,562
2021-01-14 2021-01-12 4 Stankovic Srdjan R. ACAD Common Stock S - Sale D 55.0100 -700 -39 20,247
2021-01-14 2021-01-12 4 Stankovic Srdjan R. ACAD Common Stock M - Exercise D 18.1200 700 13 20,947
2021-01-08 2021-01-06 4 YANG MICHAEL J. ACAD Restricted Stock Units M - Exercise D -2,722 8,167
2021-01-08 2021-01-06 4 YANG MICHAEL J. ACAD Common Stock S - Sale D 53.3400 -1,120 -60 8,059
2021-01-08 2021-01-06 4 YANG MICHAEL J. ACAD Common Stock M - Exercise D 2,722 9,179
2021-01-08 2021-01-06 4 KIM AUSTIN D. ACAD Restricted Stock Units M - Exercise D -1,633 4,900
2021-01-08 2021-01-06 4 KIM AUSTIN D. ACAD Common Stock S - Sale D 53.3400 -678 -36 5,518
2021-01-08 2021-01-06 4 KIM AUSTIN D. ACAD Common Stock M - Exercise D 1,633 6,196
2021-01-08 2021-01-06 4 Ridloff Elena ACAD Restricted Stock Units M - Exercise D -1,016 9,873
2021-01-08 2021-01-06 4 Ridloff Elena ACAD Common Stock S - Sale D 53.3400 -1,016 -54 3,901
2021-01-08 2021-01-06 4 Ridloff Elena ACAD Common Stock M - Exercise D 2,722 4,917
2021-01-08 2021-01-06 4 DAVIS STEPHEN ACAD Restricted Stock Units M - Exercise D -9,527 28,583
2021-01-08 2021-01-06 4 DAVIS STEPHEN ACAD Common Stock S - Sale D 53.3400 -3,484 -186 24,482
2021-01-08 2021-01-06 4 DAVIS STEPHEN ACAD Common Stock M - Exercise D 9,527 27,966
2021-01-08 2021-01-08 4 Stankovic Srdjan R. ACAD Stock Option (Right to Buy) M - Exercise D 18.12 -3,488 90,262
2021-01-08 2021-01-08 4 Stankovic Srdjan R. ACAD Stock Option (Right to Buy) M - Exercise D 21.28 -12,864 22,761
2021-01-08 2021-01-08 4 Stankovic Srdjan R. ACAD Stock Option (Right to Buy) M - Exercise D 35.80 -13,381 56,250
2021-01-08 2021-01-08 4 Stankovic Srdjan R. ACAD Common Stock S - Sale D 55.2192 -29,733 -1,642 20,247
2021-01-08 2021-01-08 4 Stankovic Srdjan R. ACAD Common Stock M - Exercise D 18.1200 3,488 63 49,980
2021-01-08 2021-01-08 4 Stankovic Srdjan R. ACAD Common Stock M - Exercise D 21.2800 12,864 274 46,492
2021-01-08 2021-01-08 4 Stankovic Srdjan R. ACAD Common Stock M - Exercise D 35.8000 13,381 479 33,628
2021-01-08 2021-01-07 4 Stankovic Srdjan R. ACAD Common Stock S - Sale D 55.1159 -61,619 -3,396 20,247
2021-01-08 2021-01-07 4 Stankovic Srdjan R. ACAD Common Stock M - Exercise D 35.8000 61,619 2,206 81,866
2021-01-08 2021-01-06 4 Stankovic Srdjan R. ACAD Stock Option (Right to Buy) M - Exercise D 35.80 -61,619 69,631
2021-01-08 2021-01-06 4 Stankovic Srdjan R. ACAD Restricted Stock Units M - Exercise D -5,444 16,333
2021-01-08 2021-01-06 4 Stankovic Srdjan R. ACAD Common Stock S - Sale D 53.3400 -1,725 -92 20,247
2021-01-08 2021-01-06 4 Stankovic Srdjan R. ACAD Common Stock M - Exercise D 5,444 21,972
2020-11-20 2020-11-20 4 Stankovic Srdjan R. ACAD Common Stock S - Sale D 53.5000 -2,728 -146 16,528
2020-11-20 2020-11-19 4 Stankovic Srdjan R. ACAD Restricted Stock Units M - Exercise D -6,250 12,500
2020-11-20 2020-11-19 4 Stankovic Srdjan R. ACAD Common Stock M - Exercise D 6,250 19,256
2020-10-29 2020-10-27 4 KIM AUSTIN D. ACAD Stock Option (Right to Buy) M - Exercise D 17.58 -8,750 113,750
2020-10-29 2020-10-27 4 KIM AUSTIN D. ACAD Common Stock S - Sale D 45.1013 -8,750 -395 3,851
2020-10-29 2020-10-27 4 KIM AUSTIN D. ACAD Common Stock M - Exercise D 17.5800 8,750 154 12,601
2020-10-19 2020-10-16 4 YANG MICHAEL J. ACAD Common Stock S - Sale D 42.5600 -1,247 -53 6,457
2020-10-19 2020-10-15 4 YANG MICHAEL J. ACAD Restricted Stock Units M - Exercise D -2,500 5,000
2020-10-19 2020-10-15 4 YANG MICHAEL J. ACAD Common Stock M - Exercise D 2,500 7,704
2020-10-19 2020-10-16 4 Stankovic Srdjan R. ACAD Common Stock S - Sale D 42.5600 -1,297 -55 13,006
2020-10-19 2020-10-15 4 Stankovic Srdjan R. ACAD Restricted Stock Units M - Exercise D -2,969 5,938
2020-10-19 2020-10-15 4 Stankovic Srdjan R. ACAD Common Stock M - Exercise D 2,969 14,303
2020-10-19 2020-10-16 4 DAVIS STEPHEN ACAD Common Stock S - Sale D 42.5600 -2,960 -126 14,786
2020-10-19 2020-10-15 4 DAVIS STEPHEN ACAD Restricted Stock Units M - Exercise D -5,937 11,876
2020-10-19 2020-10-15 4 DAVIS STEPHEN ACAD Common Stock M - Exercise D 5,937 17,746
2020-10-01 2020-09-29 4 GAROFALO ELIZABETH A. ACAD Restricted Stock Units A - Award D 3,837 3,837
2020-10-01 2020-09-29 4 GAROFALO ELIZABETH A. ACAD Stock Option (Right to Buy) A - Award D 40.41 6,865 6,865
2020-07-09 2020-07-07 4 YANG MICHAEL J. ACAD Stock Option (Right to Buy) M - Exercise D 25.12 -14,750 44,292
2020-07-09 2020-07-07 4 YANG MICHAEL J. ACAD Stock Option (Right to Buy) M - Exercise D 21.28 -5,000 25,000
2020-07-09 2020-07-07 4 YANG MICHAEL J. ACAD Stock Option (Right to Buy) M - Exercise D 19.98 -7,500 570,000
2020-07-09 2020-07-07 4 YANG MICHAEL J. ACAD Common Stock S - Sale D 56.5382 -11,100 -628 5,204
2020-07-09 2020-07-07 4 YANG MICHAEL J. ACAD Common Stock S - Sale D 56.0503 -16,150 -905 16,304
2020-07-09 2020-07-07 4 YANG MICHAEL J. ACAD Common Stock M - Exercise D 25.1200 14,750 371 32,454
2020-07-09 2020-07-07 4 YANG MICHAEL J. ACAD Common Stock M - Exercise D 21.2800 5,000 106 17,704
2020-07-09 2020-07-07 4 YANG MICHAEL J. ACAD Common Stock M - Exercise D 19.9800 7,500 150 12,704
2020-06-25 2020-06-23 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Non-Qualified Stock Options (right to buy) A - Award I 52.73 11,158 11,158
2020-06-25 2020-06-23 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock A - Award I 6,118 38,440,095
2020-06-25 2020-06-23 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock A - Award I 6,118 38,440,095
2020-06-25 2020-06-23 4 Brege Laura ACAD Restricted Stock Units A - Award D 3,059 3,059
2020-06-25 2020-06-23 4 Brege Laura ACAD Director Stock Options (Right to Buy) A - Award D 52.73 5,579 5,579
2020-06-25 2020-06-23 4 Daly James M ACAD Restricted Stock Units A - Award D 3,059 3,059
2020-06-25 2020-06-23 4 Daly James M ACAD Director Stock Options (Right to Buy) A - Award D 52.73 5,579 5,579
2020-06-25 2020-06-23 4 HARRIGAN EDMUND ACAD Restricted Stock Units A - Award D 3,059 3,059
2020-06-25 2020-06-23 4 HARRIGAN EDMUND ACAD Director Stock Options (Right to Buy) A - Award D 52.73 5,579 5,579
2020-06-25 2020-06-23 4 SOLAND DANIEL B ACAD Restricted Stock Units A - Award D 3,059 3,059
2020-06-25 2020-06-23 4 SOLAND DANIEL B ACAD Director Stock Options (Right to Buy) A - Award D 52.73 5,579 5,579
2020-06-19 2020-06-19 4 Stankovic Srdjan R. ACAD Employee Stock Option (Right to Buy) M - Exercise D 18.12 -16,452 93,750
2020-06-19 2020-06-19 4 Stankovic Srdjan R. ACAD Common Stock S - Sale D 50.1164 -16,452 -825 11,334
2020-06-19 2020-06-19 4 Stankovic Srdjan R. ACAD Common Stock M - Exercise D 18.1200 16,452 298 27,786
2020-06-19 2020-06-18 4 Stankovic Srdjan R. ACAD Employee Stock Option (Right to Buy) M - Exercise D 18.12 -39,798 110,202
2020-06-19 2020-06-18 4 Stankovic Srdjan R. ACAD Employee Stock Option (Right to Buy) M - Exercise D 19.98 -17,494 34,112
2020-06-19 2020-06-18 4 Stankovic Srdjan R. ACAD Employee Stock Option (Right to Buy) M - Exercise D 19.65 -8,551 0
2020-06-19 2020-06-18 4 Stankovic Srdjan R. ACAD Common Stock S - Sale D 50.0088 -65,843 -3,293 11,334
2020-06-19 2020-06-18 4 Stankovic Srdjan R. ACAD Common Stock M - Exercise D 18.1200 39,798 721 77,177
2020-06-19 2020-06-18 4 Stankovic Srdjan R. ACAD Common Stock M - Exercise D 19.9800 17,494 350 37,379
2020-06-19 2020-06-18 4 Stankovic Srdjan R. ACAD Common Stock M - Exercise D 19.6500 8,551 168 19,885
2020-05-15 2020-05-14 4 DAVIS STEPHEN ACAD Stock Option (Right to Buy) M - Exercise D 19.65 -88,542 100,000
2020-05-15 2020-05-14 4 DAVIS STEPHEN ACAD Common Stock S - Sale D 45.0148 -4,321 -195 11,809
2020-05-15 2020-05-14 4 DAVIS STEPHEN ACAD Common Stock S - Sale D 45.6489 -84,221 -3,845 16,130
2020-05-15 2020-05-14 4 DAVIS STEPHEN ACAD Common Stock M - Exercise D 19.6500 88,542 1,740 100,351
2020-05-15 2020-05-13 4 DAVIS STEPHEN ACAD Stock Option (Right to Buy) M - Exercise D 19.65 -111,458 188,542
2020-05-15 2020-05-13 4 DAVIS STEPHEN ACAD Common Stock S - Sale D 45.1173 -8,197 -370 11,809
2020-05-15 2020-05-13 4 DAVIS STEPHEN ACAD Common Stock S - Sale D 45.7133 -63,392 -2,898 20,006
2020-05-15 2020-05-13 4 DAVIS STEPHEN ACAD Common Stock S - Sale D 46.4302 -20,756 -964 83,398
2020-05-15 2020-05-13 4 DAVIS STEPHEN ACAD Common Stock S - Sale D 48.5981 -5,205 -253 104,154
2020-05-15 2020-05-13 4 DAVIS STEPHEN ACAD Common Stock S - Sale D 48.9822 -13,908 -681 109,359
2020-05-15 2020-05-13 4 DAVIS STEPHEN ACAD Common Stock M - Exercise D 19.6500 111,458 2,190 123,267
2020-05-13 2020-05-11 4 Daly James M ACAD Stock Option (Right to Buy) M - Exercise D 27.25 -15,000 0
2020-05-13 2020-05-11 4 Daly James M ACAD Stock Option (Right to Buy) M - Exercise D 25.24 -11,250 11,250
2020-05-13 2020-05-11 4 Daly James M ACAD Common Stock S - Sale D 51.1306 -26,250 -1,342 0
2020-05-13 2020-05-11 4 Daly James M ACAD Common Stock M - Exercise D 27.2500 15,000 409 26,250
2020-05-13 2020-05-11 4 Daly James M ACAD Common Stock M - Exercise D 25.2400 11,250 284 11,250
2020-05-01 2020-04-30 4 Stankovic Srdjan R. ACAD Common Stock S - Sale D 49.2100 -4,308 -212 11,334
2020-05-01 2020-04-29 4 Stankovic Srdjan R. ACAD Restricted Stock Units M - Exercise D -9,615 28,847
2020-05-01 2020-04-29 4 Stankovic Srdjan R. ACAD Common Stock M - Exercise D 9,615 15,642
2020-05-01 2020-04-30 4 Ridloff Elena ACAD Common Stock S - Sale D 49.2200 -1,050 -52 2,195
2020-05-01 2020-04-29 4 Ridloff Elena ACAD Restricted Stock Units M - Exercise D -3,245 9,736
2020-05-01 2020-04-29 4 Ridloff Elena ACAD Stock Option (Right to Buy) M - Exercise D 25.12 -10,000 35,547
2020-05-01 2020-04-29 4 Ridloff Elena ACAD Common Stock M - Exercise D 3,245 3,245
2020-05-01 2020-04-29 4 Ridloff Elena ACAD Common Stock S - Sale D 50.7353 -10,000 -507 0
2020-05-01 2020-04-29 4 Ridloff Elena ACAD Common Stock M - Exercise D 25.1200 10,000 251 10,000
2020-05-01 2020-04-30 4 DAVIS STEPHEN ACAD Common Stock S - Sale D 49.2100 -6,770 -333 11,809
2020-05-01 2020-04-29 4 DAVIS STEPHEN ACAD Restricted Stock Units M - Exercise D -15,625 46,875
2020-05-01 2020-04-29 4 DAVIS STEPHEN ACAD Common Stock M - Exercise D 15,625 18,579
2020-05-01 2020-04-30 4 YANG MICHAEL J. ACAD Common Stock S - Sale D 49.2100 -1,501 -74 5,204
2020-05-01 2020-04-29 4 YANG MICHAEL J. ACAD Restricted Stock Units M - Exercise D -4,206 12,621
2020-05-01 2020-04-29 4 YANG MICHAEL J. ACAD Common Stock M - Exercise D 4,206 6,705
2020-05-01 2020-04-30 4 KIM AUSTIN D. ACAD Common Stock S - Sale D 49.2200 -1,072 -53 2,441
2020-05-01 2020-04-29 4 KIM AUSTIN D. ACAD Restricted Stock Units M - Exercise D -3,004 9,015
2020-05-01 2020-04-29 4 KIM AUSTIN D. ACAD Common Stock M - Exercise D 3,004 3,513
2020-04-24 2020-04-23 4 Stankovic Srdjan R. ACAD Employee Stock Option (Right to Buy) M - Exercise D 21.28 -11,875 35,625
2020-04-24 2020-04-23 4 Stankovic Srdjan R. ACAD Employee Stock Option (Right to Buy) M - Exercise D 19.65 -7,074 8,551
2020-04-24 2020-04-23 4 Stankovic Srdjan R. ACAD Common Stock S - Sale D 50.0675 -18,949 -949 6,027
2020-04-24 2020-04-23 4 Stankovic Srdjan R. ACAD Common Stock M - Exercise D 21.2800 11,875 253 24,976
2020-04-24 2020-04-23 4 Stankovic Srdjan R. ACAD Common Stock M - Exercise D 19.6500 7,074 139 13,101
2020-04-22 2020-04-22 4 Stankovic Srdjan R. ACAD Employee Stock Option (Right to Buy) M - Exercise D 19.98 -19,644 51,606
2020-04-22 2020-04-22 4 Stankovic Srdjan R. ACAD Employee Stock Option (Right to Buy) M - Exercise D 19.65 -34,375 15,625
2020-04-22 2020-04-22 4 Stankovic Srdjan R. ACAD Common Stock S - Sale D 50.0177 -54,019 -2,702 6,027
2020-04-22 2020-04-22 4 Stankovic Srdjan R. ACAD Common Stock M - Exercise D 19.9800 19,644 392 60,046
2020-04-22 2020-04-22 4 Stankovic Srdjan R. ACAD Common Stock M - Exercise D 19.6500 34,375 675 40,402
2020-04-22 2020-04-20 4 Stankovic Srdjan R. ACAD Employee Stock Option (Right to Buy) M - Exercise D 19.65 -100,000 50,000
2020-04-22 2020-04-20 4 Stankovic Srdjan R. ACAD Common Stock S - Sale D 50.1545 -100,000 -5,015 6,027
2020-04-22 2020-04-20 4 Stankovic Srdjan R. ACAD Common Stock M - Exercise D 19.6500 100,000 1,965 106,027
2020-03-18 2020-03-18 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 34.4665 42,473 1,464 38,433,977
2020-03-18 2020-03-18 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 34.4665 3,837 132 3,470,609
2020-03-18 2020-03-18 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 33.6321 33,464 1,125 38,391,504
2020-03-18 2020-03-18 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 33.6321 3,023 102 3,466,772
2020-03-18 2020-03-18 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 32.8498 2,201 72 38,358,040
2020-03-18 2020-03-18 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 32.8498 199 7 3,463,749
2020-03-18 2020-03-18 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 32.6072 46,225 1,507 38,355,839
2020-03-18 2020-03-18 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 32.6072 4,175 136 3,463,550
2020-03-18 2020-03-18 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 31.9350 275 9 38,309,614
2020-03-18 2020-03-18 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 31.9350 25 1 3,459,375
2020-03-18 2020-03-17 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 33.8624 93,006 3,149 38,309,339
2020-03-18 2020-03-17 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 33.8624 8,402 285 3,459,350
2020-03-18 2020-03-17 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 32.3194 24,223 783 38,216,333
2020-03-18 2020-03-17 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 32.3194 2,188 71 3,450,948
2020-03-18 2020-03-17 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 32.1908 29,624 954 38,192,110
2020-03-18 2020-03-17 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 32.1908 2,676 86 3,448,760
2020-03-18 2020-03-17 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 31.8300 7,612 242 38,162,486
2020-03-18 2020-03-17 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 31.8300 688 22 3,446,084
2020-03-18 2020-03-17 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 31.7356 43,212 1,371 38,154,874
2020-03-18 2020-03-17 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 31.7356 3,903 124 3,445,396
2020-03-18 2020-03-17 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 30.9955 3,913 121 38,111,662
2020-03-18 2020-03-17 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 30.9955 353 11 3,441,493
2020-03-18 2020-03-16 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 31.5136 631,281 19,894 38,107,749
2020-03-18 2020-03-16 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 31.5136 57,022 1,797 3,441,140
2020-03-18 2020-03-16 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 31.1853 5,503 172 37,476,468
2020-03-18 2020-03-16 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 31.1853 497 15 3,384,118
2020-01-08 2020-01-06 4 DAVIS STEPHEN ACAD Restricted Stock Units A - Award D 38,110 38,110
2020-01-08 2020-01-06 4 DAVIS STEPHEN ACAD Stock Options (Right to Buy) A - Award D 42.81 138,304 138,304
2020-01-08 2020-01-06 4 Stankovic Srdjan R. ACAD Restricted Stock Units A - Award D 21,777 21,777
2020-01-08 2020-01-06 4 Stankovic Srdjan R. ACAD Stock Options (Right to Buy) A - Award D 42.81 79,031 79,031
2020-01-08 2020-01-06 4 KIM AUSTIN D. ACAD Restricted Stock Units A - Award D 6,533 6,533
2020-01-08 2020-01-06 4 KIM AUSTIN D. ACAD Stock Options (Right to Buy) A - Award D 42.81 23,709 23,709
2020-01-08 2020-01-06 4 Ridloff Elena ACAD Restricted Stock Units A - Award D 10,889 10,889
2020-01-08 2020-01-06 4 Ridloff Elena ACAD Stock Options (Right to Buy) A - Award D 42.81 39,516 39,516
2020-01-08 2020-01-06 4 YANG MICHAEL J. ACAD Restricted Stock Units A - Award D 10,889 10,889
2020-01-08 2020-01-06 4 YANG MICHAEL J. ACAD Stock Options (Right to Buy) A - Award D 42.81 39,516 39,516
2020-01-08 2020-01-07 4 Brege Laura ACAD Stock Option (Right to Buy) M - Exercise D 1.75 -10,000 0
2020-01-08 2020-01-07 4 Brege Laura ACAD Common Stock S - Sale D 42.1900 -10,000 -422 0
2020-01-08 2020-01-07 4 Brege Laura ACAD Common Stock M - Exercise D 1.7500 10,000 18 10,000
2019-12-13 2019-12-11 4 KIM AUSTIN D. ACAD Stock Option (Right to Buy) M - Exercise D 17.58 -17,500 122,500
2019-12-13 2019-12-11 4 KIM AUSTIN D. ACAD Common Stock S - Sale D 45.0615 -17,500 -789 509
2019-12-13 2019-12-11 4 KIM AUSTIN D. ACAD Common Stock M - Exercise D 17.5800 17,500 308 18,009
2019-12-13 2019-12-12 4 YANG MICHAEL J. ACAD Stock Option (Right to Buy) M - Exercise D 35.86 -72,979 312,500
2019-12-13 2019-12-12 4 YANG MICHAEL J. ACAD Stock Option (Right to Buy) M - Exercise D 21.28 -10,000 30,000
2019-12-13 2019-12-12 4 YANG MICHAEL J. ACAD Stock Option (Right to Buy) M - Exercise D 19.98 -22,500 577,500
2019-12-13 2019-12-12 4 YANG MICHAEL J. ACAD Common Stock S - Sale D 43.7350 -5,032 -220 2,499
2019-12-13 2019-12-12 4 YANG MICHAEL J. ACAD Common Stock S - Sale D 44.4930 -100,447 -4,469 7,531
2019-12-13 2019-12-12 4 YANG MICHAEL J. ACAD Common Stock M - Exercise D 35.8600 72,979 2,617 107,978
2019-12-13 2019-12-12 4 YANG MICHAEL J. ACAD Common Stock M - Exercise D 21.2800 10,000 213 34,999
2019-12-13 2019-12-12 4 YANG MICHAEL J. ACAD Common Stock M - Exercise D 19.9800 22,500 450 24,999
2019-12-11 2019-12-09 4 Ridloff Elena ACAD Stock Option (Right to Buy) M - Exercise D 15.81 -36,000 64,000
2019-12-11 2019-12-09 4 Ridloff Elena ACAD Common Stock S - Sale D 49.0940 -19,478 -956 0
2019-12-11 2019-12-09 4 Ridloff Elena ACAD Common Stock S - Sale D 49.8080 -5,502 -274 19,478
2019-12-11 2019-12-09 4 Ridloff Elena ACAD Common Stock S - Sale D 50.5950 -11,020 -558 24,980
2019-12-11 2019-12-09 4 Ridloff Elena ACAD Common Stock M - Exercise D 15.8100 36,000 569 36,000
2019-12-11 2019-12-09 4 YANG MICHAEL J. ACAD Stock Option (Right to Buy) M - Exercise D 35.86 -14,521 385,479
2019-12-11 2019-12-09 4 YANG MICHAEL J. ACAD Common Stock S - Sale D 50.0531 -3,502 -175 1,623
2019-12-11 2019-12-09 4 YANG MICHAEL J. ACAD Common Stock S - Sale D 50.5950 -11,019 -558 5,125
2019-12-11 2019-12-09 4 YANG MICHAEL J. ACAD Common Stock M - Exercise D 35.8600 14,521 521 16,144
2019-12-06 2019-12-05 4 DAVIS STEPHEN ACAD Stock Option (Right to Buy) M - Exercise D 19.65 -150,000 300,000
2019-12-06 2019-12-05 4 DAVIS STEPHEN ACAD Common Stock S - Sale D 51.3200 -28,256 -1,450 2,954
2019-12-06 2019-12-05 4 DAVIS STEPHEN ACAD Common Stock S - Sale D 52.0900 -40,159 -2,092 31,210
2019-12-06 2019-12-05 4 DAVIS STEPHEN ACAD Common Stock S - Sale D 52.8200 -81,585 -4,309 71,369
2019-12-06 2019-12-05 4 DAVIS STEPHEN ACAD Common Stock M - Exercise D 19.6500 150,000 2,948 152,954
2019-11-21 2019-11-19 4 Stankovic Srdjan R. ACAD Restricted Stock Units M - Exercise D -6,250 18,750
2019-11-21 2019-11-19 4 Stankovic Srdjan R. ACAD Common Stock S - Sale D 46.4100 -2,160 -100 6,027
2019-11-21 2019-11-19 4 Stankovic Srdjan R. ACAD Common Stock M - Exercise D 6,250 8,187
2019-10-17 2019-10-15 4 DAVIS STEPHEN ACAD Restricted Stock Units M - Exercise D -5,937 17,813
2019-10-17 2019-10-15 4 DAVIS STEPHEN ACAD Common Stock S - Sale D 39.6500 -2,983 -118 2,954
2019-10-17 2019-10-15 4 DAVIS STEPHEN ACAD Common Stock M - Exercise D 5,937 5,937
2019-10-17 2019-10-15 4 Stankovic Srdjan R. ACAD Restricted Stock Units M - Exercise D -2,968 8,907
2019-10-17 2019-10-15 4 Stankovic Srdjan R. ACAD Common Stock S - Sale D 39.6500 -1,031 -41 1,937
2019-10-17 2019-10-15 4 Stankovic Srdjan R. ACAD Common Stock M - Exercise D 2,968 2,968
2019-10-17 2019-10-15 4 YANG MICHAEL J. ACAD Restricted Stock Units M - Exercise D -2,500 7,500
2019-10-17 2019-10-15 4 YANG MICHAEL J. ACAD Common Stock S - Sale D 39.6500 -877 -35 1,623
2019-10-17 2019-10-15 4 YANG MICHAEL J. ACAD Common Stock M - Exercise D 2,500 2,500
2019-10-17 2019-10-15 4 Miller Eric Alejandro ACAD Restricted Stock Units M - Exercise D -417 1,254
2019-10-17 2019-10-15 4 Miller Eric Alejandro ACAD Common Stock S - Sale D 39.6500 -147 -6 270
2019-10-17 2019-10-15 4 Miller Eric Alejandro ACAD Common Stock M - Exercise D 417 417
2019-10-11 2019-10-10 4 DAVIS STEPHEN ACAD Stock Option (Right to Buy) M - Exercise D 19.65 -120,208 450,000
2019-10-11 2019-10-10 4 DAVIS STEPHEN ACAD Common Stock S - Sale D 40.1890 -120,208 -4,831 0
2019-10-11 2019-10-10 4 DAVIS STEPHEN ACAD Common Stock M - Exercise D 19.6500 120,208 2,362 120,208
2019-10-11 2019-10-09 4 DAVIS STEPHEN ACAD Stock Option (Right to Buy) M - Exercise D 19.65 -29,792 570,208
2019-10-11 2019-10-09 4 DAVIS STEPHEN ACAD Common Stock S - Sale D 40.0010 -29,792 -1,192 0
2019-10-11 2019-10-09 4 DAVIS STEPHEN ACAD Common Stock M - Exercise D 19.6500 29,792 585 29,792
2019-09-20 2019-09-20 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 40.0000 1,494,025 59,761 37,470,965
2019-09-20 2019-09-20 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 40.0000 68,475 2,739 3,383,621
2019-09-11 2019-09-11 4 Miller Eric Alejandro ACAD Common Stock S - Sale D 41.1800 -4,645 -191 0
2019-09-11 2019-09-09 4 Miller Eric Alejandro ACAD Stock Option (Right to Buy) M - Exercise D 16.50 -1,972 3,598
2019-09-11 2019-09-09 4 Miller Eric Alejandro ACAD Stock Option (Right to Buy) M - Exercise D 35.80 -4,593 4,594
2019-09-11 2019-09-09 4 Miller Eric Alejandro ACAD Stock Option (Right to Buy) M - Exercise D 36.54 -4,439 2,911
2019-09-11 2019-09-09 4 Miller Eric Alejandro ACAD Stock Option (Right to Buy) M - Exercise D 29.24 -6,063 552
2019-09-11 2019-09-09 4 Miller Eric Alejandro ACAD Stock Option (Right to Buy) M - Exercise D 32.28 -3,900 0
2019-09-11 2019-09-09 4 Miller Eric Alejandro ACAD Stock Option (Right to Buy) M - Exercise D 20.65 -7,500 0
2019-09-11 2019-09-09 4 Miller Eric Alejandro ACAD Common Stock S - Sale D 39.4900 -28,467 -1,124 4,645
2019-09-11 2019-09-09 4 Miller Eric Alejandro ACAD Common Stock M - Exercise D 16.5000 1,972 33 33,112
2019-09-11 2019-09-09 4 Miller Eric Alejandro ACAD Common Stock M - Exercise D 35.8000 4,593 164 31,140
2019-09-11 2019-09-09 4 Miller Eric Alejandro ACAD Common Stock M - Exercise D 36.5400 4,439 162 26,547
2019-09-11 2019-09-09 4 Miller Eric Alejandro ACAD Common Stock M - Exercise D 29.2400 6,063 177 22,108
2019-09-11 2019-09-09 4 Miller Eric Alejandro ACAD Common Stock M - Exercise D 32.2800 3,900 126 16,045
2019-09-11 2019-09-09 4 Miller Eric Alejandro ACAD Common Stock M - Exercise D 20.6500 7,500 155 12,145
2019-09-11 2019-09-09 4 Daly James M ACAD Stock Option (Right to Buy) M - Exercise D 17.52 -30,000 0
2019-09-11 2019-09-09 4 Daly James M ACAD Common Stock S - Sale D 38.3900 -400 -15 0
2019-09-11 2019-09-09 4 Daly James M ACAD Common Stock S - Sale D 37.7873 -29,600 -1,119 400
2019-09-11 2019-09-09 4 Daly James M ACAD Common Stock M - Exercise D 17.5200 30,000 526 30,000
2019-06-28 2019-06-26 4 HARRIGAN EDMUND ACAD Stock Option (Right to Buy) A - Award D 25.24 -22,500 22,500
2019-06-28 2019-06-26 4 Daly James M ACAD Stock Option (Right to Buy) A - Award D 25.24 -22,500 22,500
2019-06-28 2019-06-26 4 SOLAND DANIEL B ACAD Stock Option (Right to Buy) A - Award D 25.24 -22,500 22,500
2019-06-28 2019-06-26 4 Brege Laura ACAD Stock Option (Right to Buy) A - Award D 25.24 -15,000 15,000
2019-06-28 2019-06-26 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Non-Qualified Stock Option (right to buy) A - Award I 25.24 30,000 30,000
2019-06-07 2019-06-06 4 BAKER BROS. ADVISORS LP ACAD Common Stock J - Other D 31,229 102,876
2019-06-07 2019-06-06 4 BAKER BROS. ADVISORS LP ACAD Common Stock J - Other D 31,229 102,876
2019-06-07 2019-06-06 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock J - Other I -421,756 3,315,146
2019-05-01 2019-04-29 4 DAVIS STEPHEN ACAD Restricted Stock Units A - Award D 62,500 62,500
2019-05-01 2019-04-29 4 DAVIS STEPHEN ACAD Stock Options (Right to Buy) A - Award D 25.12 219,298 219,298
2019-05-01 2019-04-29 4 Stankovic Srdjan R. ACAD Restricted Stock Units A - Award D 38,462 38,462
2019-05-01 2019-04-29 4 Stankovic Srdjan R. ACAD Stock Options (Right to Buy) A - Award D 25.12 134,953 134,953
2019-05-01 2019-04-29 4 KIM AUSTIN D. ACAD Restricted Stock Units A - Award D 12,019 12,019
2019-05-01 2019-04-29 4 KIM AUSTIN D. ACAD Stock Options (Right to Buy) A - Award D 25.12 42,173 42,173
2019-05-01 2019-04-29 4 Ridloff Elena ACAD Restricted Stock Units A - Award D 12,981 12,981
2019-05-01 2019-04-29 4 Ridloff Elena ACAD Stock Options (Right to Buy) A - Award D 25.12 45,547 45,547
2019-05-01 2019-04-29 4 YANG MICHAEL J. ACAD Restricted Stock Units A - Award D 16,827 16,827
2019-05-01 2019-04-29 4 YANG MICHAEL J. ACAD Stock Options (Right to Buy) A - Award D 25.12 59,042 59,042
2019-05-01 2019-04-29 4 Miller Eric Alejandro ACAD Restricted Stock Units A - Award D 3,442 3,442
2019-05-01 2019-04-29 4 Miller Eric Alejandro ACAD Stock Options (Right to Buy) A - Award D 25.12 6,039 6,039
2019-04-02 2019-04-01 4 Ridloff Elena ACAD Restricted Stock Units A - Award D 40,000 40,000
2019-01-11 2019-01-09 4 Brege Laura ACAD Stock Option (Right to Buy) M - Exercise D 2.16 -10,000 0
2019-01-11 2019-01-09 4 Brege Laura ACAD Common Stock S - Sale D 20.0041 -10,000 -200 0
2019-01-11 2019-01-09 4 Brege Laura ACAD Common Stock M - Exercise D 2.1600 10,000 22 10,000
2018-12-04 2018-11-30 4 BAKER BROS. ADVISORS LP ACAD Common Stock Warrant (right to buy) J - Other D 0.01 1,569 1,569
2018-12-04 2018-11-30 4 BAKER BROS. ADVISORS LP ACAD Common Stock Warrant (right to buy) J - Other D 0.01 1,569 1,569
2018-12-04 2018-11-30 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock Warrant (right to buy) J - Other I 0.01 -10,731 0
2018-12-04 2018-11-30 4 BAKER BROS. ADVISORS LP ACAD Common Stock J - Other D 71,647 71,647
2018-12-04 2018-11-30 4 BAKER BROS. ADVISORS LP ACAD Common Stock J - Other D 71,647 71,647
2018-12-04 2018-11-30 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock J - Other I -489,977 0
2018-12-04 2018-11-30 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 17.0000 11,178,823 190,040 35,976,940
2018-12-04 2018-11-30 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 17.0000 585,882 9,960 3,736,902
2018-11-20 2018-11-19 4 Stankovic Srdjan R. ACAD Restricted Stock Units A - Award D 25,000 25,000
2018-11-20 2018-11-19 4 Stankovic Srdjan R. ACAD Employee Stock Options (Right to Buy) A - Award D 18.12 150,000 150,000
2018-11-09 3 Miller Eric Alejandro ACAD Common Stock D 6,424
2018-11-09 3 Miller Eric Alejandro ACAD Common Stock D 6,424
2018-11-09 3 Miller Eric Alejandro ACAD Common Stock D 6,424
2018-10-24 2018-10-15 4 DAVIS STEPHEN ACAD Restricted Stock Units A - Award D 23,750 23,750
2018-10-24 2018-10-15 4 DAVIS STEPHEN ACAD Stock Option(right to buy) A - Award D 21.28 95,000 95,000
2018-10-24 2018-10-15 4 Stankovic Srdjan R. ACAD Restricted Stock Units A - Award D 11,875 11,875
2018-10-24 2018-10-15 4 Stankovic Srdjan R. ACAD Stock Option (right to buy) A - Award D 21.28 47,500 47,500
2018-10-24 2018-10-15 4 YANG MICHAEL J. ACAD Restricted Stock Units A - Award D 10,000 10,000
2018-10-24 2018-10-15 4 YANG MICHAEL J. ACAD Stock Option (right to buy) A - Award D 21.28 40,000 40,000
2018-10-24 2018-10-15 4 YOUNG TODD S. ACAD Restricted Stock Units A - Award D 4,688 4,688
2018-10-24 2018-10-15 4 YOUNG TODD S. ACAD Stock Option (right to buy) A - Award D 21.28 18,750 18,750
2018-09-24 2018-09-20 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 19.0924 131,007 2,501 24,798,117
2018-09-24 2018-09-20 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 19.0924 14,555 278 3,151,020
2018-09-24 2018-09-20 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 19.0110 38,207 726 24,667,110
2018-09-24 2018-09-20 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 19.0110 4,245 81 3,136,465
2018-09-24 2018-09-20 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 18.6366 920,495 17,155 24,628,903
2018-09-24 2018-09-20 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 18.6366 102,267 1,906 3,132,220
2018-07-20 2018-07-18 4 KIM AUSTIN D. ACAD Stock Option (right to buy) A - Award D 17.58 140,000 140,000
2018-06-08 2018-06-06 4 Brege Laura ACAD Stock option (right to buy) A - Award D 17.52 15,000 15,000
2018-06-08 2018-06-06 4 Daly James M ACAD Stock Option (right to buy) A - Award D 17.52 15,000 15,000
2018-06-08 2018-06-06 4 Daly James M ACAD Stock Option (right to buy) A - Award D 17.52 15,000 15,000
2018-06-08 2018-06-06 4 HARRIGAN EDMUND ACAD Stock Option (right to buy) A - Award D 17.52 15,000 15,000
2018-06-08 2018-06-06 4 HARRIGAN EDMUND ACAD Stock Option (right to buy) A - Award D 17.52 15,000 15,000
2018-06-08 2018-06-06 4 SOLAND DANIEL B ACAD Stock Option (right to buy) A - Award D 17.52 15,000 15,000
2018-06-08 2018-06-06 4 SOLAND DANIEL B ACAD Stock Option (right to buy) A - Award D 17.52 15,000 15,000
2018-06-08 2018-06-06 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Non-Qualified Stock Option (right to buy) A - Award I 17.52 30,000 30,000
2018-04-20 2018-04-18 4 Baity Glenn ACAD Stock Option (right to buy) A - Award D 19.98 28,125 28,125
2018-04-20 2018-04-18 4 DAVIS STEPHEN ACAD Stock Option (right to buy) A - Award D 19.98 135,000 135,000
2018-04-20 2018-04-18 4 Stankovic Srdjan R. ACAD Stock Option (right to buy) A - Award D 19.98 71,250 71,250
2018-04-20 2018-04-18 4 YANG MICHAEL J. ACAD Stock Option (right to buy) A - Award D 19.98 60,000 60,000
2018-04-20 2018-04-18 4 YOUNG TODD S. ACAD Stock Option (right to buy) A - Award D 19.98 28,125 28,125
2018-03-02 2018-03-02 4 SOLAND DANIEL B ACAD Common Stock P - Purchase D 22.5200 3,000 68 10,000
2018-03-02 2018-03-01 4 SOLAND DANIEL B ACAD Common Stock P - Purchase D 24.5200 2,000 49 7,000
2018-03-02 2018-03-01 4 SOLAND DANIEL B ACAD Common Stock P - Purchase D 24.0900 3,000 72 5,000
2018-03-02 2018-03-01 4 SOLAND DANIEL B ACAD Common Stock P - Purchase D 23.0200 2,000 46 2,000
2018-01-31 2018-01-29 4 Baity Glenn ACAD Common Stock S - Sale D 32.3884 -36,558 -1,184 83,734
2018-01-11 2018-01-10 4 Baity Glenn ACAD Stock Option (right to buy) M - Exercise D 2.18 -50,179 0
2018-01-11 2018-01-10 4 Baity Glenn ACAD Common Stock M - Exercise D 2.1800 50,179 109 120,292
2018-01-04 2018-01-02 4 Brege Laura ACAD Stock option (right to buy) M - Exercise D 8.49 -10,000 0
2018-01-04 2018-01-02 4 Brege Laura ACAD Stock option (right to buy) M - Exercise D 8.06 -15,000 0
2018-01-04 2018-01-02 4 Brege Laura ACAD Common Stock S - Sale D 30.0617 -25,000 -752 0
2018-01-04 2018-01-02 4 Brege Laura ACAD Common Stock M - Exercise D 8.4900 10,000 85 25,000
2018-01-04 2018-01-02 4 Brege Laura ACAD Common Stock M - Exercise D 8.0600 15,000 121 15,000
2018-01-04 2018-01-02 4 Baity Glenn ACAD Stock Option (right to buy) M - Exercise D 2.18 -74,321 0
2018-01-04 2018-01-02 4 Baity Glenn ACAD Common Stock S - Sale D 30.1414 -74,321 -2,240 70,113
2018-01-04 2018-01-02 4 Baity Glenn ACAD Common Stock M - Exercise D 2.1800 74,321 162 144,434
2017-11-29 2017-11-27 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock Warrant (right to buy) M - Exercise I 1.38 -39,378 0
2017-11-29 2017-11-27 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock F - Taxes I 28.0000 -1,941 -54 489,977
2017-11-29 2017-11-27 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock M - Exercise I 1.3800 39,378 54 491,918
2017-10-16 2017-10-13 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock Warrant (right to buy) M - Exercise I 1.38 -1,426,590 0
2017-10-16 2017-10-13 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock F - Taxes I 35.4000 -55,457 -1,963 23,708,408
2017-10-16 2017-10-13 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock M - Exercise I 1.3800 1,426,590 1,969 23,763,865
2017-10-06 2017-10-05 4 Baity Glenn ACAD Stock Option (right to buy) M - Exercise D 2.00 -20,000 0
2017-10-06 2017-10-05 4 Baity Glenn ACAD Stock Option (right to buy) M - Exercise D 1.62 -7,500 0
2017-10-06 2017-10-05 4 Baity Glenn ACAD Stock Option (right to buy) M - Exercise D 2.18 -1,000 124,500
2017-10-06 2017-10-05 4 Baity Glenn ACAD Common Stock S - Sale D 40.9078 -37,500 -1,534 69,656
2017-10-06 2017-10-05 4 Baity Glenn ACAD Common Stock M - Exercise D 2.0000 20,000 40 107,156
2017-10-06 2017-10-05 4 Baity Glenn ACAD Common Stock M - Exercise D 1.6200 7,500 12 99,656
2017-10-06 2017-10-05 4 Baity Glenn ACAD Common Stock M - Exercise D 2.1800 1,000 2 79,656
2017-10-06 2017-10-04 4 Baity Glenn ACAD Stock Option (right to buy) M - Exercise D 2.18 -4,500 125,500
2017-10-06 2017-10-04 4 Baity Glenn ACAD Stock Option (right to buy) M - Exercise D 1.62 -6,500 7,500
2017-10-06 2017-10-04 4 Baity Glenn ACAD Common Stock M - Exercise D 2.1800 4,500 10 78,656
2017-10-06 2017-10-04 4 Baity Glenn ACAD Common Stock M - Exercise D 1.6200 6,500 11 74,156
2017-09-08 2017-09-07 4 Stankovic Srdjan R. ACAD Stock Option (right to buy) A - Award D 35.80 131,250 131,250
2017-09-08 2017-09-07 4 YANG MICHAEL J. ACAD Stock Option (right to buy) A - Award D 35.80 93,750 93,750
2017-09-08 2017-09-07 4 Baity Glenn ACAD Stock Option (right to buy) A - Award D 35.80 46,875 46,875
2017-09-08 2017-09-07 4 YOUNG TODD S. ACAD Stock Option (right to buy) A - Award D 35.80 56,250 56,250
2017-09-08 2017-09-07 4 DAVIS STEPHEN ACAD Stock Option (right to buy) A - Award D 35.80 243,750 243,750
2017-09-01 2017-08-30 4 Baity Glenn ACAD Stock Option (right to buy) M - Exercise D 1.62 -16,507 14,000
2017-09-01 2017-08-30 4 Baity Glenn ACAD Common Stock S - Sale D 34.8706 -26,507 -924 67,656
2017-09-01 2017-08-30 4 Baity Glenn ACAD Common Stock M - Exercise D 1.6200 16,507 27 94,163
2017-08-11 2017-08-09 4 Baity Glenn ACAD Stock Option (right to buy) M - Exercise D 1.62 -13,400 30,507
2017-08-11 2017-08-09 4 Baity Glenn ACAD Stock Option (right to buy) M - Exercise D 1.55 -922 0
2017-08-11 2017-08-09 4 Baity Glenn ACAD Common Stock S - Sale D 34.8788 -14,322 -500 77,656
2017-08-11 2017-08-09 4 Baity Glenn ACAD Common Stock M - Exercise D 1.6200 13,400 22 91,978
2017-08-11 2017-08-09 4 Baity Glenn ACAD Common Stock M - Exercise D 1.5500 922 1 78,578
2017-08-08 2017-08-04 4 Baity Glenn ACAD Stock Option (right to buy) M - Exercise D 1.62 -6,500 43,907
2017-08-08 2017-08-04 4 Baity Glenn ACAD Common Stock M - Exercise D 1.6200 6,500 11 77,656
2017-07-21 2017-07-20 4 Baity Glenn ACAD Stock Option (right to buy) M - Exercise D 1.62 -28,097 28,000
2017-07-21 2017-07-20 4 Baity Glenn ACAD Common Stock S - Sale D 30.0000 -38,097 -1,143 71,156
2017-07-21 2017-07-20 4 Baity Glenn ACAD Common Stock M - Exercise D 1.6200 28,097 46 109,253
2017-07-19 2017-07-17 4 SOLAND DANIEL B ACAD Stock Option (right to buy) A - Award D 28.85 15,000 15,000
2017-07-19 2017-07-17 4 HARRIGAN EDMUND ACAD Stock Option (right to buy) A - Award D 28.85 15,000 15,000
2017-07-19 2017-07-17 4 Daly James M ACAD Stock Option (right to buy) A - Award D 28.85 15,000 15,000
2017-06-26 2017-06-22 4 Baity Glenn ACAD Stock Option (right to buy) M - Exercise D 1.62 -1,903 56,097
2017-06-26 2017-06-22 4 Baity Glenn ACAD Common Stock S - Sale D 30.0004 -1,903 -57 81,156
2017-06-26 2017-06-22 4 Baity Glenn ACAD Common Stock M - Exercise D 1.6200 1,903 3 83,059
2017-06-14 2017-06-13 4 HARRIGAN EDMUND ACAD Stock Option (right to buy) A - Award D 27.25 15,000 15,000
2017-06-14 2017-06-13 4 Brege Laura ACAD Stock Option (right to buy) A - Award D 27.25 15,000 15,000
2017-06-14 2017-06-13 4 Daly James M ACAD Stock Option (right to buy) A - Award D 27.25 15,000 15,000
2017-06-14 2017-06-13 4 SOLAND DANIEL B ACAD Stock Option (right to buy) A - Award D 27.25 15,000 15,000
2017-06-14 2017-06-13 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Non-Qualified Stock Option (right to buy) A - Award I 27.25 30,000 30,000
2017-05-17 2017-05-15 4 Baity Glenn ACAD Stock Option (right to buy) M - Exercise D 1.62 -14,093 58,000
2017-05-17 2017-05-15 4 Baity Glenn ACAD Common Stock M - Exercise D 1.6200 14,093 23 81,156
2017-03-31 2017-03-29 4 YANG MICHAEL J. ACAD Stock Option (right to buy) A - Award D 35.86 400,000 400,000
2017-03-10 2017-03-08 4 Moore Terrence O ACAD Stock Option (right to buy) A - Award D 36.54 33,750 33,750
2017-03-10 2017-03-08 4 Stankovic Srdjan R. ACAD Stock Option (right to buy) A - Award D 36.54 93,750 93,750
2017-03-10 2017-03-08 4 YOUNG TODD S. ACAD Stock Option (right to buy) A - Award D 36.54 37,500 37,500
2017-03-10 2017-03-08 4 DAVIS STEPHEN ACAD Stock Option (right to buy) A - Award D 36.54 243,750 243,750
2017-03-10 2017-03-08 4 Baity Glenn ACAD Stock Option (right to buy) A - Award D 36.54 46,875 46,875
2017-02-23 2017-02-21 4 Moore Terrence O ACAD Stock Option (right to buy) M - Exercise D 34.45 -7,856 82,500
2017-02-23 2017-02-21 4 Moore Terrence O ACAD Common Stock S - Sale D 39.6500 -7,856 -311 1,671
2017-02-23 2017-02-21 4 Moore Terrence O ACAD Common Stock M - Exercise D 34.4500 7,856 271 9,527
2017-02-16 2017-02-14 4 Baity Glenn ACAD Stock Option (right to buy) M - Exercise D 1.64 -6,365 0
2017-02-16 2017-02-14 4 Baity Glenn ACAD Stock Option (right to buy) M - Exercise D 8.32 -3,224 0
2017-02-16 2017-02-14 4 Baity Glenn ACAD Stock Option (right to buy) M - Exercise D 8.32 -16,776 0
2017-02-16 2017-02-14 4 Baity Glenn ACAD Common Stock S - Sale D 39.6555 -26,365 -1,046 67,063
2017-02-16 2017-02-14 4 Baity Glenn ACAD Common Stock M - Exercise D 1.6400 6,365 10 93,428
2017-02-16 2017-02-14 4 Baity Glenn ACAD Common Stock M - Exercise D 8.3200 20,000 166 87,063
2017-02-16 2017-02-16 4 Moore Terrence O ACAD Stock Option (right to buy) M - Exercise D 34.35 -29,644 90,356
2017-02-16 2017-02-16 4 Moore Terrence O ACAD Stock Option (right to buy) M - Exercise D 27.20 -19,687 13,125
2017-02-16 2017-02-16 4 Moore Terrence O ACAD Stock Option (right to buy) M - Exercise D 19.61 -17,421 36,102
2017-02-16 2017-02-16 4 Moore Terrence O ACAD Common Stock S - Sale D 39.8807 -66,752 -2,662 1,671
2017-02-16 2017-02-16 4 Moore Terrence O ACAD Common Stock M - Exercise D 34.4500 29,644 1,021 68,423
2017-02-16 2017-02-16 4 Moore Terrence O ACAD Common Stock M - Exercise D 27.2000 19,687 535 38,779
2017-02-16 2017-02-16 4 Moore Terrence O ACAD Common Stock M - Exercise D 19.6100 17,421 342 19,092
2017-02-16 2017-02-15 4 Moore Terrence O ACAD Stock Option (right to buy) M - Exercise D 19.61 -1,700 53,523
2017-02-16 2017-02-15 4 Moore Terrence O ACAD Common Stock S - Sale D 39.6500 -1,700 -67 1,671
2017-02-16 2017-02-15 4 Moore Terrence O ACAD Common Stock M - Exercise D 19.6100 1,700 33 3,371
2017-02-16 2017-02-14 4 Moore Terrence O ACAD Stock Option (right to buy) M - Exercise D 19.61 -74,381 55,223
2017-02-16 2017-02-14 4 Moore Terrence O ACAD Stock Option (right to buy) M - Exercise D 19.61 -12,747 7,649
2017-02-16 2017-02-14 4 Moore Terrence O ACAD Common Stock S - Sale D 39.6863 -89,088 -3,536 1,671
2017-02-16 2017-02-14 4 Moore Terrence O ACAD Common Stock M - Exercise D 19.6100 87,128 1,709 90,759
2017-02-03 2017-02-01 4 Baity Glenn ACAD Stock Option (right to buy) M - Exercise D 1.55 -21,078 0
2017-02-03 2017-02-01 4 Baity Glenn ACAD Common Stock S - Sale D 35.1497 -31,078 -1,092 67,063
2017-02-03 2017-02-01 4 Baity Glenn ACAD Common Stock M - Exercise D 1.5500 21,078 33 98,141
2016-12-29 2016-12-28 4 Baity Glenn ACAD Stock Option (right to buy) M - Exercise D 1.62 -5,500 72,093
2016-12-29 2016-12-28 4 Baity Glenn ACAD Common Stock M - Exercise D 1.6200 5,500 9 77,063
2016-12-29 2016-12-27 4 Baity Glenn ACAD Stock Option (right to buy) M - Exercise D 1.55 -9,800 21,078
2016-12-29 2016-12-27 4 Baity Glenn ACAD Common Stock S - Sale D 30.4565 -9,800 -298 71,563
2016-12-29 2016-12-27 4 Baity Glenn ACAD Common Stock M - Exercise D 1.5500 9,800 15 81,363
2016-12-21 2016-12-20 4 Baity Glenn ACAD Stock Option (right to buy) M - Exercise D 1.55 -10,000 30,878
2016-12-21 2016-12-20 4 Baity Glenn ACAD Common Stock S - Sale D 30.0001 -10,000 -300 71,563
2016-12-21 2016-12-20 4 Baity Glenn ACAD Common Stock M - Exercise D 1.5500 10,000 16 81,563
2016-12-21 2016-12-19 4 Baity Glenn ACAD Stock Option (right to buy) M - Exercise D 1.64 -8,635 0
2016-12-21 2016-12-19 4 Baity Glenn ACAD Common Stock M - Exercise D 1.6400 8,635 14 71,563
2016-11-14 2016-11-10 4 Baity Glenn ACAD Stock Option (right to buy) M - Exercise D 1.55 -10,200 40,878
2016-11-14 2016-11-10 4 Baity Glenn ACAD Common Stock S - Sale D 30.0674 -10,200 -307 62,921
2016-11-14 2016-11-10 4 Baity Glenn ACAD Common Stock M - Exercise D 1.5500 10,200 16 73,121
2016-08-24 2016-08-22 4 YOUNG TODD S. ACAD Stock Option (right to buy) A - Award D 34.32 200,000 200,000
2016-08-18 2016-08-16 4 HARRIGAN EDMUND ACAD Common Stock P - Purchase D 32.9700 1,000 33 1,000
2016-08-12 2016-08-10 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 33.0000 1,169,877 38,606 22,337,275
2016-08-12 2016-08-10 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 33.0000 133,153 4,394 3,029,953
2016-07-13 2016-07-12 4 Baity Glenn ACAD Stock Option (right to buy) M - Exercise D 6.78 -2,625 0
2016-07-13 2016-07-12 4 Baity Glenn ACAD Stock Option (right to buy) M - Exercise D 6.78 -3,375 0
2016-07-13 2016-07-12 4 Baity Glenn ACAD Stock Option (right to buy) M - Exercise D 6.78 -645 0
2016-07-13 2016-07-12 4 Baity Glenn ACAD Stock Option (right to buy) M - Exercise D 6.78 -5,298 0
2016-07-13 2016-07-12 4 Baity Glenn ACAD Common Stock S - Sale D 35.0022 -11,943 -418 62,921
2016-07-13 2016-07-12 4 Baity Glenn ACAD Common Stock M - Exercise D 6.7800 2,625 18 74,864
2016-07-13 2016-07-12 4 Baity Glenn ACAD Common Stock M - Exercise D 6.7800 3,375 23 72,239
2016-07-13 2016-07-12 4 Baity Glenn ACAD Common Stock M - Exercise D 6.7800 645 4 68,864
2016-07-13 2016-07-12 4 Baity Glenn ACAD Common Stock M - Exercise D 6.7800 5,298 36 68,219
2016-07-13 2016-07-11 4 Baity Glenn ACAD Stock Option (right to buy) M - Exercise D 6.78 -4,057 5,298
2016-07-13 2016-07-11 4 Baity Glenn ACAD Common Stock S - Sale D 35.0016 -4,057 -142 62,921
2016-07-13 2016-07-11 4 Baity Glenn ACAD Common Stock M - Exercise D 6.7800 4,057 28 66,978
2016-06-13 2016-06-10 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Non-Qualified Stock Option (right to buy) A - Award I 39.60 26,500 26,500
2016-06-10 2016-06-10 4 HARRIGAN EDMUND ACAD Stock Option (right to buy) A - Award D 39.60 12,500 12,500
2016-06-10 2016-06-10 4 SOLAND DANIEL B ACAD Stock Option (right to buy) A - Award D 39.60 12,500 12,500
2016-06-10 2016-06-10 4 Brege Laura ACAD Stock option (right to buy) A - Award D 39.60 12,500 12,500
2016-06-10 2016-06-10 4 Daly James M ACAD Stock Option (right to buy) A - Award D 39.60 12,500 12,500
2016-06-09 2016-06-07 4 GRAY MARY ANN ACAD Stock option (right to buy) M - Exercise D 9.04 -10,000 0
2016-06-09 2016-06-07 4 GRAY MARY ANN ACAD Stock option (right to buy) M - Exercise D 9.04 -6,637 0
2016-06-09 2016-06-07 4 GRAY MARY ANN ACAD Common Stock M - Exercise D 9.0400 10,000 90 149,476
2016-06-09 2016-06-07 4 GRAY MARY ANN ACAD Common Stock M - Exercise D 9.0400 6,637 60 139,476
2016-04-20 2016-04-18 4 Iversen Leslie L ACAD Stock option (right to buy) M - Exercise D 1.75 -33,697 0
2016-04-20 2016-04-18 4 Iversen Leslie L ACAD Common Stock S - Sale D 33.5341 -33,697 -1,130 36,127
2016-04-20 2016-04-18 4 Iversen Leslie L ACAD Common Stock M - Exercise D 1.7500 33,697 59 69,824
2016-04-07 2016-04-07 4 GRAY MARY ANN ACAD Stock option (right to buy) M - Exercise D 1.36 1.3600 -10,000 -14 0
2016-04-07 2016-04-07 4 GRAY MARY ANN ACAD Stock option (right to buy) M - Exercise D 1.36 1.3600 -55,147 -75 0
2016-04-07 2016-04-07 4 GRAY MARY ANN ACAD Stock option (right to buy) M - Exercise D 1.30 1.3000 -57,692 -75 0
2016-04-07 2016-04-07 4 GRAY MARY ANN ACAD Stock option (right to buy) M - Exercise D 1.30 1.3000 -10,000 -13 0
2016-04-07 2016-04-07 4 GRAY MARY ANN ACAD Common Stock M - Exercise D 1.3600 10,000 14 132,839
2016-04-07 2016-04-07 4 GRAY MARY ANN ACAD Common Stock M - Exercise D 1.3600 55,147 75 122,839
2016-04-07 2016-04-07 4 GRAY MARY ANN ACAD Common Stock M - Exercise D 1.3000 57,692 75 67,692
2016-04-07 2016-04-07 4 GRAY MARY ANN ACAD Common Stock M - Exercise D 1.3000 10,000 13 10,000
2016-04-01 2016-04-01 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 28.5484 262,253 7,487 21,167,398
2016-04-01 2016-04-01 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 28.5484 28,647 818 2,896,800
2016-04-01 2016-04-01 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 27.8202 10,818 301 20,905,145
2016-04-01 2016-04-01 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 27.8202 1,182 33 2,868,153
2016-04-01 2016-03-31 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 27.7173 318,969 8,841 20,894,327
2016-04-01 2016-03-31 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 27.7173 34,844 966 2,866,971
2016-04-01 2016-03-31 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 27.5588 60,587 1,670 20,575,358
2016-04-01 2016-03-31 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 27.5588 6,618 182 2,832,127
2016-04-01 2016-03-31 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 26.5545 28,433 755 20,514,771
2016-04-01 2016-03-31 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 26.5545 3,106 82 2,825,509
2016-04-01 2016-03-31 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 26.4944 180,122 4,772 20,486,338
2016-04-01 2016-03-31 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 26.4944 19,676 521 2,822,403
2016-04-01 2016-03-31 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 26.2850 13,433 353 20,306,216
2016-04-01 2016-03-31 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 26.2850 1,467 39 2,802,727
2016-04-01 2016-03-31 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 25.6070 14,775 378 20,292,783
2016-04-01 2016-03-31 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 25.6070 1,614 41 2,801,260
2016-04-01 2016-03-30 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 26.3472 16,057 423 2,799,646
2016-04-01 2016-03-30 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 25.9750 37,882 984 2,783,589
2016-04-01 2016-03-30 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 25.9247 408,607 10,593 2,745,707
2016-03-17 2016-03-15 4 DAVIS STEPHEN ACAD Stock Option (right to buy) A - Award D 19.65 600,000 600,000
2016-03-17 2016-03-15 4 Stankovic Srdjan R. ACAD Stock Option (right to buy) A - Award D 19.65 150,000 150,000
2016-03-17 2016-03-15 4 Moore Terrence O ACAD Stock Option (right to buy) A - Award D 19.65 150,000 150,000
2016-03-17 2016-03-15 4 Baity Glenn ACAD Stock Option (right to buy) A - Award D 19.65 150,000 150,000
2016-03-04 2016-03-02 4 Baity Glenn ACAD Stock Option (right to buy) M - Exercise D 15.37 -7,000 0
2016-03-04 2016-03-02 4 Baity Glenn ACAD Common Stock S - Sale D 20.7971 -7,000 -146 62,921
2016-03-04 2016-03-02 4 Baity Glenn ACAD Common Stock M - Exercise D 15.3700 7,000 108 69,921
2016-01-11 2016-01-07 4 Daly James M ACAD Stock Option (right to buy) A - Award D 28.73 15,000 15,000
2016-01-08 2016-01-07 4/A BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 29.0000 1,801,161 52,234 20,278,008
2016-01-08 2016-01-07 4/A BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 29.0000 785,045 22,766 2,337,100
2016-01-08 2016-01-07 4 14159, L.P. See Footnotes ACAD Common Stock P - Purchase I 29.0000 1,801,161 52,234 20,278,008
2016-01-08 2016-01-07 4 14159, L.P. See Footnotes ACAD Common Stock P - Purchase I 29.0000 785,045 22,766 2,337,100
2015-12-15 2015-12-11 4 BAKER BROS. ADVISORS LP ACAD Non-Qualified Stock Option (right to buy) A - Award I 32.50 15,000 15,000
2015-11-30 2015-11-25 4 HARRIGAN EDMUND ACAD Stock Option (right to buy) A - Award D 38.28 15,000 15,000
2015-11-30 2015-11-25 4 Stankovic Srdjan R. ACAD Stock Option (right to buy) A - Award D 38.28 250,000 250,000
2015-11-13 2015-11-11 4 Iversen Leslie L ACAD Stock option (right to buy) M - Exercise D 1.75 -4,874 33,697
2015-11-13 2015-11-11 4 Iversen Leslie L ACAD Stock option (right to buy) M - Exercise D 9.04 -9,126 0
2015-11-13 2015-11-11 4 Iversen Leslie L ACAD Stock option (right to buy) M - Exercise D 9.04 -10,000 0
2015-11-13 2015-11-11 4 Iversen Leslie L ACAD Stock option (right to buy) M - Exercise D 9.04 -6,000 0
2015-11-13 2015-11-11 4 Iversen Leslie L ACAD Common Stock S - Sale D 36.0109 -30,000 -1,080 36,127
2015-11-13 2015-11-11 4 Iversen Leslie L ACAD Common Stock M - Exercise D 1.7500 4,874 9 66,127
2015-11-13 2015-11-11 4 Iversen Leslie L ACAD Common Stock M - Exercise D 9.0400 9,126 82 61,253
2015-11-13 2015-11-11 4 Iversen Leslie L ACAD Common Stock M - Exercise D 9.0400 10,000 90 52,127
2015-11-13 2015-11-11 4 Iversen Leslie L ACAD Common Stock M - Exercise D 9.0400 6,000 54 42,127
2015-09-03 2015-09-01 4 DAVIS STEPHEN ACAD Stock Option (right to buy) A - Award D 35.91 225,000 225,000
2015-08-21 2015-08-19 4 Iversen Leslie L ACAD Stock option (right to buy) M - Exercise D 11.00 -8,500 0
2015-08-21 2015-08-19 4 Iversen Leslie L ACAD Common Stock M - Exercise D 11.0000 8,500 94 36,127
2015-08-21 2015-08-19 4 Iversen Leslie L ACAD Stock option (right to buy) M - Exercise D 11.00 -8,500 0
2015-08-21 2015-08-19 4 Iversen Leslie L ACAD Common Stock M - Exercise D 11.0000 8,500 94 36,127
2015-08-13 2015-08-11 4 KAPLAN LESTER J PH D ACAD Stock option (right to buy) M - Exercise D 11.00 -8,500 0
2015-08-13 2015-08-11 4 KAPLAN LESTER J PH D ACAD Common Stock M - Exercise D 11.0000 8,500 94 17,000
2015-06-17 2015-06-15 4 KAPLAN LESTER J PH D ACAD Stock option (right to buy) A - Award D 39.06 12,500 12,500
2015-06-17 2015-06-15 4 KAPLAN LESTER J PH D ACAD Stock option (right to buy) A - Award D 39.06 12,500 12,500
2015-06-17 2015-06-15 4 BORER MICHAEL T ACAD Stock Option (right to buy) A - Award D 39.06 12,500 12,500
2015-06-17 2015-06-15 4 GRAY MARY ANN ACAD Stock option (right to buy) A - Award D 39.06 12,500 12,500
2015-06-17 2015-06-15 4 Iversen Leslie L ACAD Stock option (right to buy) A - Award D 39.06 14,000 14,000
2015-06-17 2015-06-15 4 Rasmussen Torsten ACAD Stock option (right to buy) A - Award I 39.06 12,500 12,500
2015-06-17 2015-06-15 4 SOLAND DANIEL B ACAD Stock Option (right to buy) A - Award D 39.06 12,500 12,500
2015-06-17 2015-06-15 4 Brege Laura ACAD Stock option (right to buy) A - Award D 39.06 12,500 12,500
2015-06-17 2015-06-15 4 Wells William McDowall ACAD Stock Option (right to buy) A - Award D 39.06 12,500 12,500
2015-06-17 2015-06-15 4 BAKER BROS. ADVISORS LP ACAD Non-Qualified Stock Option (right to buy) A - Award I 39.06 12,500 12,500
2015-06-03 2015-06-01 4 Iversen Leslie L ACAD Stock option (right to buy) M - Exercise D 8.85 -7,627 0
2015-06-03 2015-06-01 4 Iversen Leslie L ACAD Stock option (right to buy) M - Exercise D 8.85 -6,500 0
2015-06-03 2015-06-01 4 Iversen Leslie L ACAD Common Stock M - Exercise D 8.8500 7,627 67 27,627
2015-06-03 2015-06-01 4 Iversen Leslie L ACAD Common Stock M - Exercise D 8.8500 6,500 58 20,000
2015-03-24 2015-03-20 4 DAVIS STEPHEN ACAD Stock Option (right to buy) A - Award D 34.45 120,000 120,000
2015-03-24 2015-03-20 4 DAVIS STEPHEN ACAD Stock Option (right to buy) A - Award D 34.45 100,000 100,000
2015-03-24 2015-03-20 4 SOLAND DANIEL B ACAD Stock Option (right to buy) A - Award D 34.45
2015-03-24 2015-03-20 4 Mills Roger ACAD Stock Option (right to buy) A - Award D 34.45 180,000 180,000
2015-03-24 2015-03-20 4 Moore Terrence O ACAD Stock Option (right to buy) A - Award D 34.45 120,000 120,000
2015-03-24 2015-03-20 4 Baity Glenn ACAD Stock Option (right to buy) A - Award D 34.45 120,000 120,000
2015-02-19 2015-02-17 4 Rasmussen Torsten ACAD Stock option (right to buy) M - Exercise I 1.36 -10,000 0
2015-02-19 2015-02-17 4 Rasmussen Torsten ACAD Stock option (right to buy) M - Exercise I 8.49 -7,067 0
2015-02-19 2015-02-17 4 Rasmussen Torsten ACAD Stock option (right to buy) M - Exercise I 8.49 -2,780 0
2015-02-19 2015-02-17 4 Rasmussen Torsten ACAD Common Stock S - Sale I 35.0453 -19,847 -696 8,500
2015-02-19 2015-02-17 4 Rasmussen Torsten ACAD Common Stock M - Exercise I 1.3600 10,000 14 28,347
2015-02-19 2015-02-17 4 Rasmussen Torsten ACAD Common Stock M - Exercise I 8.4900 7,067 60 18,347
2015-02-19 2015-02-17 4 Rasmussen Torsten ACAD Common Stock M - Exercise I 8.4900 2,780 24 11,280
2015-02-19 2015-02-17 4 Hacksell Uli ACAD Stock Option (right to buy) M - Exercise D 1.55 -30,000 313,500
2015-02-19 2015-02-17 4 Hacksell Uli By Family Trust ACAD Common Stock S - Sale I 34.2956 -30,000 -1,029 115,549
2015-02-19 2015-02-17 4 Hacksell Uli By Family Trust ACAD Common Stock G - Gift I 30,000 145,549
2015-02-19 2015-02-17 4 Hacksell Uli ACAD Common Stock G - Gift D -30,000 0
2015-02-19 2015-02-17 4 Hacksell Uli ACAD Common Stock M - Exercise D 1.5500 30,000 46 30,000
2015-02-13 2015-02-11 4 Brege Laura ACAD Stock option (right to buy) M - Exercise D 1.75 -10,000 0
2015-02-13 2015-02-11 4 Brege Laura ACAD Common Stock S - Sale D 33.6349 -10,000 -336 0
2015-02-13 2015-02-11 4 Brege Laura ACAD Common Stock M - Exercise D 1.7500 10,000 18 10,000
2015-01-16 2015-01-15 4 BORER MICHAEL T ACAD Stock Option (right to buy) M - Exercise D 15.02 -2,996 0
2015-01-16 2015-01-15 4 BORER MICHAEL T ACAD Stock Option (right to buy) M - Exercise D 15.02 -10,000 0
2015-01-16 2015-01-15 4 BORER MICHAEL T ACAD Stock Option (right to buy) M - Exercise D 9.04 -10,000 0
2015-01-16 2015-01-15 4 BORER MICHAEL T ACAD Stock Option (right to buy) M - Exercise D 9.04 -4,977 0
2015-01-16 2015-01-15 4 BORER MICHAEL T ACAD Common Stock S - Sale D 33.0235 -27,973 -924 0
2015-01-16 2015-01-15 4 BORER MICHAEL T ACAD Common Stock M - Exercise D 15.0200 2,996 45 27,973
2015-01-16 2015-01-15 4 BORER MICHAEL T ACAD Common Stock M - Exercise D 15.0200 10,000 150 24,977
2015-01-16 2015-01-15 4 BORER MICHAEL T ACAD Common Stock M - Exercise D 9.0400 4,977 45 14,977
2015-01-16 2015-01-15 4 BORER MICHAEL T ACAD Common Stock M - Exercise D 9.0400 10,000 90 10,000
2015-01-16 2015-01-14 4 Hacksell Uli ACAD Stock Option (right to buy) M - Exercise D 2.00 -30,000 0
2015-01-16 2015-01-14 4 Hacksell Uli By Family Trust ACAD Common Stock S - Sale I 33.9810 -30,000 -1,019 115,549
2015-01-16 2015-01-14 4 Hacksell Uli By Family Trust ACAD Common Stock G - Gift I 30,000 145,549
2015-01-16 2015-01-14 4 Hacksell Uli ACAD Common Stock G - Gift D -30,000 0
2015-01-16 2015-01-14 4 Hacksell Uli ACAD Common Stock M - Exercise D 2.0000 30,000 60 30,000
2015-01-15 2015-01-13 4 Rasmussen Torsten ACAD Stock option (right to buy) M - Exercise I 8.49 -7,220 2,780
2015-01-15 2015-01-13 4 Rasmussen Torsten ACAD Stock option (right to buy) M - Exercise I 15.02 -4,685 0
2015-01-15 2015-01-13 4 Rasmussen Torsten ACAD Common Stock S - Sale I 35.0001 -11,905 -417 8,500
2015-01-15 2015-01-13 4 Rasmussen Torsten ACAD Common Stock M - Exercise I 8.4900 7,220 61 20,405
2015-01-15 2015-01-13 4 Rasmussen Torsten ACAD Common Stock M - Exercise I 15.0200 4,685 70 13,185
2015-01-15 2015-01-13 4 GRAY MARY ANN ACAD Stock option (right to buy) M - Exercise D 11.00 -4,250 0
2015-01-15 2015-01-13 4 GRAY MARY ANN ACAD Common Stock S - Sale D 35.0000 -4,250 -149 0
2015-01-15 2015-01-13 4 GRAY MARY ANN ACAD Common Stock M - Exercise D 11.0000 4,250 47 4,250
2014-12-17 2014-12-15 4 Hacksell Uli ACAD Stock Option (right to buy) M - Exercise D 2.00 -30,000 30,000
2014-12-17 2014-12-15 4 Hacksell Uli By Family Trust ACAD Common Stock S - Sale I 30.9972 -30,000 -930 115,549
2014-12-17 2014-12-15 4 Hacksell Uli By Family Trust ACAD Common Stock G - Gift I 30,000 145,549
2014-12-17 2014-12-15 4 Hacksell Uli ACAD Common Stock G - Gift D -30,000 0
2014-12-17 2014-12-15 4 Hacksell Uli ACAD Common Stock M - Exercise D 2.0000 30,000 60 30,000
2014-12-17 2014-12-15 4 GRAY MARY ANN ACAD Stock option (right to buy) M - Exercise D 11.00 -4,250 4,250
2014-12-17 2014-12-15 4 GRAY MARY ANN ACAD Stock option (right to buy) M - Exercise D 8.85 -6,500 0
2014-12-17 2014-12-15 4 GRAY MARY ANN ACAD Stock option (right to buy) M - Exercise D 7.67 -1,500 0
2014-12-17 2014-12-15 4 GRAY MARY ANN ACAD Common Stock S - Sale D 31.7400 -12,250 -389 0
2014-12-17 2014-12-15 4 GRAY MARY ANN ACAD Common Stock M - Exercise D 11.0000 4,250 47 12,250
2014-12-17 2014-12-15 4 GRAY MARY ANN ACAD Common Stock M - Exercise D 8.8500 6,500 58 8,000
2014-12-17 2014-12-15 4 GRAY MARY ANN ACAD Common Stock M - Exercise D 7.6700 1,500 12 1,500
2014-12-10 2014-12-09 4 Baity Glenn ACAD Stock Option (right to buy) M - Exercise D 1.55 -8,000 52,000
2014-12-10 2014-12-09 4 Baity Glenn ACAD Common Stock M - Exercise D 1.5500 8,000 12 62,423
2014-11-26 2014-11-26 4 BORER MICHAEL T ACAD Stock Option (right to buy) M - Exercise D 11.00 -15,000 0
2014-11-26 2014-11-26 4 BORER MICHAEL T ACAD Common Stock S - Sale D 30.0510 -15,000 -451 0
2014-11-26 2014-11-26 4 BORER MICHAEL T ACAD Common Stock M - Exercise D 11.0000 15,000 165 15,000
2014-11-26 2014-11-26 4 Mills Roger ACAD Stock Option (right to buy) M - Exercise D 1.55 -25,000 139,035
2014-11-26 2014-11-26 4 Mills Roger ACAD Common Stock S - Sale D 30.0906 -25,000 -752 18,550
2014-11-26 2014-11-26 4 Mills Roger ACAD Common Stock M - Exercise D 25,000 43,550
2014-11-26 2014-11-24 4 Hacksell Uli ACAD Stock Option (right to buy) M - Exercise D 2.00 -30,000 60,000
2014-11-26 2014-11-24 4 Hacksell Uli By Family Trust ACAD Common Stock S - Sale I 29.2799 -30,000 -878 115,549
2014-11-26 2014-11-24 4 Hacksell Uli By Family Trust ACAD Common Stock G - Gift I 30,000 145,549
2014-11-26 2014-11-24 4 Hacksell Uli ACAD Common Stock G - Gift D -30,000 0
2014-11-26 2014-11-24 4 Hacksell Uli ACAD Common Stock M - Exercise D 2.0000 30,000 60 30,000
2014-11-21 2014-11-21 4 Wells William McDowall ACAD Stock Option (right to buy) M - Exercise D 1.36 -5,810 9,117
2014-11-21 2014-11-21 4 Wells William McDowall ACAD Common Stock S - Sale D 29.0000 -5,810 -168 0
2014-11-21 2014-11-21 4 Wells William McDowall ACAD Common Stock M - Exercise D 1.3600 5,810 8 5,810
2014-10-10 2014-10-08 4 Hacksell Uli ACAD Stock Option (right to buy) M - Exercise D 2.00 -30,000 90,000
2014-10-10 2014-10-08 4 Hacksell Uli By Family Trust ACAD Common Stock S - Sale I 24.1510 -30,000 -725 115,549
2014-10-10 2014-10-08 4 Hacksell Uli By Family Trust ACAD Common Stock G - Gift I 30,000 145,549
2014-10-10 2014-10-08 4 Hacksell Uli ACAD Common Stock G - Gift D -30,000 0
2014-10-10 2014-10-08 4 Hacksell Uli ACAD Common Stock M - Exercise D 2.0000 30,000 60 30,000
2014-09-16 2014-09-12 4 Wells William McDowall ACAD Stock Option (right to buy) M - Exercise D 1.36 -9,190 14,927
2014-09-16 2014-09-12 4 Wells William McDowall ACAD Common Stock S - Sale D 29.1483 -9,190 -268 0
2014-09-16 2014-09-12 4 Wells William McDowall ACAD Common Stock M - Exercise D 1.3600 9,190 12 9,190
2014-09-16 2014-09-15 4 Brege Laura ACAD Stock option (right to buy) M - Exercise D 1.75 -10,000 10,000
2014-09-16 2014-09-15 4 Brege Laura ACAD Common Stock S - Sale D 28.0669 -10,000 -281 0
2014-09-16 2014-09-15 4 Brege Laura ACAD Common Stock M - Exercise D 1.7500 10,000 18 10,000
2014-09-12 2014-09-10 4 Hacksell Uli ACAD Stock Option (right to buy) M - Exercise D 2.00 -30,000 120,000
2014-09-12 2014-09-10 4 Hacksell Uli By Family Trust ACAD Common Stock S - Sale I 27.3607 -30,000 -821 115,549
2014-09-12 2014-09-10 4 Hacksell Uli By Family Trust ACAD Common Stock G - Gift I 30,000 145,549
2014-09-12 2014-09-10 4 Hacksell Uli ACAD Common Stock G - Gift D -30,000 0
2014-09-12 2014-09-10 4 Hacksell Uli ACAD Common Stock M - Exercise D 2.0000 30,000 60 30,000
2014-09-09 2014-09-05 4 Baity Glenn ACAD Stock Option (right to buy) A - Award D 26.96 25,000 25,000
2014-09-04 2014-09-02 4 KAPLAN LESTER J PH D ACAD Stock option (right to buy) M - Exercise D 1.30 -57,692 0
2014-09-04 2014-09-02 4 KAPLAN LESTER J PH D ACAD Common Stock S - Sale D 26.7600 -57,692 -1,544 8,500
2014-09-04 2014-09-02 4 KAPLAN LESTER J PH D ACAD Common Stock M - Exercise D 1.3000 57,692 75 66,192
2014-09-04 2014-09-02 4 Wells William McDowall ACAD Stock option (right to buy) M - Exercise D 1.36 -20,000 24,117
2014-09-04 2014-09-02 4 Wells William McDowall ACAD Stock Option (right to buy) M - Exercise D 1.36 -10,000 0
2014-09-04 2014-09-02 4 Wells William McDowall ACAD Common Stock S - Sale D 27.0000 -15,000 -405 0
2014-09-04 2014-09-02 4 Wells William McDowall ACAD Common Stock S - Sale D 26.7600 -15,000 -401 15,000
2014-09-04 2014-09-02 4 Wells William McDowall ACAD Common Stock M - Exercise D 1.3600 30,000 41 30,000
2014-08-15 2014-08-15 4 Hacksell Uli ACAD Stock Option (right to buy) M - Exercise D 6.86 -15,000 0
2014-08-15 2014-08-15 4 Hacksell Uli By Family Trust ACAD Common Stock S - Sale I 22.8914 -15,000 -343 115,549
2014-08-15 2014-08-15 4 Hacksell Uli By Family Trust ACAD Common Stock G - Gift I 15,000 130,549
2014-08-15 2014-08-15 4 Hacksell Uli ACAD Common Stock G - Gift D -15,000 0
2014-08-15 2014-08-15 4 Hacksell Uli ACAD Common Stock M - Exercise D 6.8600 15,000 103 15,000
2014-07-16 2014-07-15 4 DAVIS STEPHEN ACAD Stock Option (right to buy) A - Award D 20.77 320,000 320,000
2014-07-16 2014-07-14 4 Hacksell Uli ACAD Stock Option (right to buy) M - Exercise D 6.86 -20,000 15,000
2014-07-16 2014-07-14 4 Hacksell Uli By Family Trust ACAD Common Stock S - Sale I 22.2187 -20,000 -444 115,549
2014-07-16 2014-07-14 4 Hacksell Uli By Family Trust ACAD Common Stock G - Gift I 20,000 135,549
2014-07-16 2014-07-14 4 Hacksell Uli ACAD Common Stock G - Gift D -20,000 0
2014-07-16 2014-07-14 4 Hacksell Uli ACAD Common Stock M - Exercise D 6.8600 20,000 137 20,000
2014-06-18 2014-06-16 4 Hacksell Uli ACAD Stock Option (right to buy) M - Exercise D 6.86 -20,000 35,000
2014-06-18 2014-06-16 4 Hacksell Uli By Family Trust ACAD Common Stock S - Sale I 23.1002 -20,000 -462 115,549
2014-06-18 2014-06-16 4 Hacksell Uli By Family Trust ACAD Common Stock G - Gift I 20,000 135,549
2014-06-18 2014-06-16 4 Hacksell Uli ACAD Common Stock G - Gift D -20,000 0
2014-06-18 2014-06-16 4 Hacksell Uli ACAD Common Stock M - Exercise D 6.8600 20,000 137 20,000
2014-06-10 2014-06-06 4 KAPLAN LESTER J PH D ACAD Stock option (right to buy) A - Award D 21.99 12,500 12,500
2014-06-10 2014-06-06 4 BORER MICHAEL T ACAD Stock Option (right to buy) A - Award D 21.99 12,500 12,500
2014-06-10 2014-06-06 4 GRAY MARY ANN ACAD Stock option (right to buy) A - Award D 21.99 12,500 12,500
2014-06-10 2014-06-06 4 Iversen Leslie L ACAD Stock option (right to buy) A - Award D 21.99 14,000 14,000
2014-06-10 2014-06-06 4 Rasmussen Torsten ACAD Stock option (right to buy) A - Award I 21.99 12,500 12,500
2014-06-10 2014-06-06 4 Brege Laura ACAD Stock option (right to buy) A - Award D 21.99 12,500 12,500
2014-06-10 2014-06-06 4 Wells William McDowall ACAD Stock Option (right to buy) A - Award D 21.99 12,500 12,500
2014-06-10 2014-06-09 4 Wells William McDowall ACAD Stock option (right to buy) M - Exercise D 1.60 -15,000 0
2014-06-10 2014-06-09 4 Wells William McDowall ACAD Common Stock S - Sale D 23.0304 -15,000 -345 0
2014-06-10 2014-06-09 4 Wells William McDowall ACAD Common Stock M - Exercise D 1.6000 15,000 24 15,000
2014-06-10 2014-06-06 4 BAKER BROS. ADVISORS LP ACAD Non-Qualified Stock Option (right to buy) A - Award I 21.99 12,500 12,500
2014-06-04 2014-06-02 4 KAPLAN LESTER J PH D ACAD Stock option (right to buy) M - Exercise D 6.10 -4,450 0
2014-06-04 2014-06-02 4 KAPLAN LESTER J PH D ACAD Common Stock S - Sale D 20.5249 -4,450 -91 8,500
2014-06-04 2014-06-02 4 KAPLAN LESTER J PH D ACAD Common Stock M - Exercise D 6.1000 4,450 27 12,950
2014-05-02 2014-05-01 4 Rasmussen Torsten ACAD Stock option (right to buy) M - Exercise I 15.02 -5,315 4,685
2014-05-02 2014-05-01 4 Rasmussen Torsten ACAD Stock option (right to buy) M - Exercise I 9.04 -10,000 0
2014-05-02 2014-05-01 4 Rasmussen Torsten ACAD Stock option (right to buy) M - Exercise I 11.00 -8,500 0
2014-05-02 2014-05-01 4 Rasmussen Torsten ACAD Stock option (right to buy) M - Exercise I 8.85 -2,542 0
2014-05-02 2014-05-01 4 Rasmussen Torsten ACAD Stock option (right to buy) M - Exercise I 8.85 -6,500 0
2014-05-02 2014-05-01 4 Rasmussen Torsten ACAD Common Stock S - Sale I 20.0333 -32,857 -658 8,500
2014-05-02 2014-05-01 4 Rasmussen Torsten ACAD Common Stock M - Exercise I 15.0200 5,315 80 41,357
2014-05-02 2014-05-01 4 Rasmussen Torsten ACAD Common Stock M - Exercise I 9.0400 10,000 90 36,042
2014-05-02 2014-05-01 4 Rasmussen Torsten ACAD Common Stock M - Exercise I 11.0000 8,500 94 26,042
2014-05-02 2014-05-01 4 Rasmussen Torsten ACAD Common Stock M - Exercise I 8.8500 2,542 22 17,542
2014-05-02 2014-05-01 4 Rasmussen Torsten ACAD Common Stock M - Exercise I 8.8500 6,500 58 15,000
2014-04-17 2014-04-15 4 Hacksell Uli ACAD Stock Option (right to buy) M - Exercise D 6.95 -25,000 0
2014-04-17 2014-04-15 4 Hacksell Uli By Family Trust ACAD Common Stock S - Sale I 17.7534 -25,000 -444 115,549
2014-04-17 2014-04-15 4 Hacksell Uli By Family Trust ACAD Common Stock G - Gift I 25,000 140,549
2014-04-17 2014-04-15 4 Hacksell Uli ACAD Common Stock G - Gift D -25,000 0
2014-04-17 2014-04-15 4 Hacksell Uli ACAD Common Stock M - Exercise D 6.9500 25,000 174 25,000
2014-04-04 2014-04-04 4 Rasmussen Torsten ACAD Stock option (right to buy) M - Exercise I 1.75 -15,500 27,357
2014-04-04 2014-04-04 4 Rasmussen Torsten ACAD Stock option (right to buy) M - Exercise I 1.75 -10,000 0
2014-04-04 2014-04-04 4 Rasmussen Torsten ACAD Stock option (right to buy) M - Exercise I 6.10 -4,500 0
2014-04-04 2014-04-04 4 Rasmussen Torsten ACAD Common Stock S - Sale I 21.9795 -30,000 -659 8,500
2014-04-04 2014-04-04 4 Rasmussen Torsten ACAD Common Stock M - Exercise I 1.7500 15,500 27 38,500
2014-04-04 2014-04-04 4 Rasmussen Torsten ACAD Common Stock M - Exercise I 1.7500 10,000 18 23,000
2014-04-04 2014-04-04 4 Rasmussen Torsten ACAD Common Stock M - Exercise I 6.1000 4,500 27 13,000
2014-04-04 2014-04-04 4 Aasen Thomas H ACAD Stock Option (right to buy) M - Exercise D 1.55 -7,500 82,971
2014-04-04 2014-04-04 4 Aasen Thomas H By Family Trust ACAD Common Stock S - Sale I 22.4840 -15,000 -337 0
2014-04-04 2014-04-04 4 Aasen Thomas H By Family Trust ACAD Common Stock G - Gift I 15,000 15,000
2014-04-04 2014-04-04 4 Aasen Thomas H ACAD Common Stock G - Gift D -15,000 23,848
2014-04-04 2014-04-04 4 Aasen Thomas H ACAD Common Stock M - Exercise D 1.5500 7,500 12 38,848
2014-04-04 2014-04-04 4 Brege Laura ACAD Stock option (right to buy) M - Exercise D 1.75 -14,285 20,000
2014-04-04 2014-04-04 4 Brege Laura ACAD Common Stock S - Sale D 22.5359 -14,285 -322 0
2014-04-04 2014-04-04 4 Brege Laura ACAD Common Stock M - Exercise D 1.7500 14,285 25 14,285
2014-03-11 2014-03-07 4 Hacksell Uli ACAD Stock Option (right to buy) A - Award D 27.20 250,000 250,000
2014-03-11 2014-03-07 4 Mills Roger ACAD Stock Option (right to buy) A - Award D 27.20 155,000 155,000
2014-03-11 2014-03-07 4 Moore Terrence O ACAD Stock Option (right to buy) A - Award D 27.20 35,000 35,000
2014-03-11 2014-03-07 4 Baity Glenn ACAD Stock Option (right to buy) A - Award D 27.20 115,000 115,000
2014-03-07 2014-03-05 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 28.5000 11,738 335 452,540
2014-03-07 2014-03-05 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 28.5000 475,644 13,556 18,476,847
2014-03-07 2014-03-05 4 BAKER BROS. ADVISORS LP See Footnotes ACAD Common Stock P - Purchase I 28.5000 38,934 1,110 1,552,055
2014-02-28 2014-02-26 4 Baity Glenn ACAD Stock Option (right to buy) M - Exercise D 6.17 -42,000 0
2014-02-28 2014-02-26 4 Baity Glenn ACAD Common Stock S - Sale D 30.2790 -42,000 -1,272 47,788
2014-02-28 2014-02-26 4 Baity Glenn ACAD Common Stock M - Exercise D 6.1700 42,000 259 89,788
2014-02-20 2014-02-18 4 Hacksell Uli ACAD Stock Option (right to buy) M - Exercise D 6.95 -25,000 25,000
2014-02-20 2014-02-18 4 Hacksell Uli By Family Trust ACAD Common Stock S - Sale I 24.1411 -25,000 -604 115,549
2014-02-20 2014-02-18 4 Hacksell Uli By Family Trust ACAD Common Stock G - Gift I 25,000 140,549
2014-02-20 2014-02-18 4 Hacksell Uli ACAD Common Stock G - Gift D -25,000 0
2014-02-20 2014-02-18 4 Hacksell Uli ACAD Common Stock M - Exercise D 6.9500 25,000 174 25,000
2014-01-17 2014-01-15 4 Hacksell Uli ACAD Stock Option (right to buy) M - Exercise D 6.95 -25,000 50,000
2014-01-17 2014-01-15 4 Hacksell Uli By Family Trust ACAD Common Stock S - Sale I 24.0115 -25,000 -600 115,549
2014-01-17 2014-01-15 4 Hacksell Uli By Family Trust ACAD Common Stock G - Gift I 25,000 140,549
2014-01-17 2014-01-15 4 Hacksell Uli ACAD Common Stock G - Gift D -25,000 0
2014-01-17 2014-01-15 4 Hacksell Uli ACAD Common Stock M - Exercise D 6.9500 25,000 174 25,000
2014-01-17 2014-01-15 4 Brege Laura ACAD Stock option (right to buy) M - Exercise D 1.36 -10,000 0
2014-01-17 2014-01-15 4 Brege Laura ACAD Common Stock S - Sale D 24.1764 -10,000 -242 0
2014-01-17 2014-01-15 4 Brege Laura ACAD Common Stock M - Exercise D 1.3600 10,000 14 10,000
2014-01-03 2014-01-02 4 Aasen Thomas H ACAD Stock Option (right to buy) M - Exercise D 1.55 -22,000 90,471
2014-01-03 2014-01-02 4 Aasen Thomas H By Family Trust ACAD Common Stock S - Sale I 24.8778 -30,000 -746 0
2014-01-03 2014-01-02 4 Aasen Thomas H By Family Trust ACAD Common Stock G - Gift I 30,000 30,000
2014-01-03 2014-01-02 4 Aasen Thomas H ACAD Common Stock G - Gift D -30,000 31,348
2014-01-03 2014-01-02 4 Aasen Thomas H ACAD Common Stock M - Exercise D 1.5500 22,000 34 61,348
2014-01-03 2014-01-02 4 Iversen Leslie L ACAD Stock option (right to buy) M - Exercise D 1.30 -29,500 0
2014-01-03 2014-01-02 4 Iversen Leslie L ACAD Stock option (right to buy) M - Exercise D 2.16 -20,500 7,277
2014-01-03 2014-01-02 4 Iversen Leslie L ACAD Stock option (right to buy) M - Exercise D 2.16 -10,000 0
2014-01-03 2014-01-02 4 Iversen Leslie L ACAD Common Stock S - Sale D 25.0292 -60,000 -1,502 13,500
2014-01-03 2014-01-02 4 Iversen Leslie L ACAD Common Stock M - Exercise D 1.3000 29,500 38 73,500
2014-01-03 2014-01-02 4 Iversen Leslie L ACAD Common Stock M - Exercise D 2.1600 20,500 44 44,000
2014-01-03 2014-01-02 4 Iversen Leslie L ACAD Common Stock M - Exercise D 2.1600 10,000 22 23,500
2013-12-18 2013-12-17 4 Hacksell Uli ACAD Stock Option (right to buy) M - Exercise D 1.55 -6,500 343,500
2013-12-18 2013-12-17 4 Hacksell Uli By Family Trust ACAD Common Stock G - Gift I 6,500 115,549
2013-12-18 2013-12-17 4 Hacksell Uli ACAD Common Stock G - Gift D -6,500 0
2013-12-18 2013-12-17 4 Hacksell Uli ACAD Common Stock M - Exercise D 1.5500 6,500 10 6,500
2013-12-16 2013-12-12 4 Aasen Thomas H ACAD Stock Option (right to buy) M - Exercise D 6.95 -1,000 25,000
2013-12-16 2013-12-12 4 Aasen Thomas H ACAD Stock Option (right to buy) M - Exercise D 1.55 -11,000 112,471
2013-12-16 2013-12-12 4 Aasen Thomas H ACAD Common Stock M - Exercise D 6.9500 1,000 7 39,348
2013-12-16 2013-12-12 4 Aasen Thomas H ACAD Common Stock M - Exercise D 1.5500 11,000 17 38,348
2013-12-16 2013-12-02 4 Aasen Thomas H ACAD Common Stock G - Gift D -2,000 27,348
2013-12-12 2013-12-10 4 Brege Laura ACAD Stock option (right to buy) M - Exercise D 1.36 -44,117 0
2013-12-12 2013-12-10 4 Brege Laura ACAD Common Stock S - Sale D 23.4130 -44,117 -1,033 0
2013-12-12 2013-12-10 4 Brege Laura ACAD Common Stock M - Exercise D 1.3600 44,117 60 44,117
2013-12-04 2013-12-02 4 Hacksell Uli ACAD Stock Option (right to buy) M - Exercise D 2.00 -15,000 0
2013-12-04 2013-12-02 4 Hacksell Uli By Family Trust ACAD Common Stock S - Sale I 23.4538 -15,000 -352 109,049
2013-12-04 2013-12-02 4 Hacksell Uli By Family Trust ACAD Common Stock G - Gift I 15,000 124,049
2013-12-04 2013-12-02 4 Hacksell Uli ACAD Common Stock G - Gift D -15,000 0
2013-12-04 2013-12-02 4 Hacksell Uli ACAD Common Stock M - Exercise D 2.0000 15,000 30 15,000
2013-11-01 2013-11-01 4 Hacksell Uli ACAD Stock Option (right to buy) M - Exercise D 2.00 -15,000 15,000
2013-11-01 2013-11-01 4 Hacksell Uli By Family Trust ACAD Common Stock S - Sale I 23.2425 -15,000 -349 109,049
2013-11-01 2013-11-01 4 Hacksell Uli By Family Trust ACAD Common Stock G - Gift I 15,000 124,049
2013-11-01 2013-11-01 4 Hacksell Uli ACAD Common Stock G - Gift D -15,000 0
2013-11-01 2013-11-01 4 Hacksell Uli ACAD Common Stock M - Exercise D 2.0000 15,000 30 15,000
2013-11-01 2013-11-01 4 Rasmussen Torsten ACAD Stock option (right to buy) M - Exercise I 1.30 -37,692 0
2013-11-01 2013-11-01 4 Rasmussen Torsten ACAD Common Stock S - Sale I 23.0031 -37,692 -867 8,500
2013-11-01 2013-11-01 4 Rasmussen Torsten ACAD Common Stock M - Exercise I 1.3000 37,692 49 46,192
2013-10-11 2013-10-10 4 Brege Laura ACAD Stock option (right to buy) M - Exercise D 1.30 -10,000 0
2013-10-11 2013-10-10 4 Brege Laura ACAD Common Stock S - Sale D 21.6256 -10,000 -216 0
2013-10-11 2013-10-10 4 Brege Laura ACAD Common Stock M - Exercise D 1.3000 10,000 13 10,000
2013-10-03 2013-10-01 4 Aasen Thomas H ACAD Stock Option (right to buy) M - Exercise D 1.55 -17,500 123,471
2013-10-03 2013-10-01 4 Aasen Thomas H ACAD Stock Option (right to buy) M - Exercise D 6.95 -5,000 26,000
2013-10-03 2013-10-01 4 Aasen Thomas H By Family Trust ACAD Common Stock S - Sale I 27.8707 -30,000 -836 0
2013-10-03 2013-10-01 4 Aasen Thomas H By Family Trust ACAD Common Stock G - Gift I 30,000 30,000
2013-10-03 2013-10-01 4 Aasen Thomas H ACAD Common Stock G - Gift D -30,000 24,085
2013-10-03 2013-10-01 4 Aasen Thomas H ACAD Common Stock M - Exercise D 1.5500 17,500 27 54,085
2013-10-03 2013-10-01 4 Aasen Thomas H ACAD Common Stock M - Exercise D 6.9500 5,000 35 36,585
2013-09-20 2013-09-20 4 Mills Roger ACAD Stock Option (right to buy) M - Exercise D 1.55 -35,965 164,035
2013-09-20 2013-09-20 4 Mills Roger ACAD Common Stock S - Sale D 25.0052 -35,965 -899 15,775
2013-09-20 2013-09-20 4 Mills Roger ACAD Common Stock M - Exercise D 35,965 51,740
2013-09-13 2013-09-12 4 KAPLAN LESTER J PH D ACAD Stock option (right to buy) M - Exercise D 2.16 -34,722 0
2013-09-13 2013-09-12 4 KAPLAN LESTER J PH D ACAD Stock option (right to buy) M - Exercise D 9.04 -10,000 0
2013-09-13 2013-09-12 4 KAPLAN LESTER J PH D ACAD Stock option (right to buy) M - Exercise D 2.16 -10,000 0
2013-09-13 2013-09-12 4 KAPLAN LESTER J PH D ACAD Stock option (right to buy) M - Exercise D 8.85 -5,084 0
2013-09-13 2013-09-12 4 KAPLAN LESTER J PH D ACAD Stock option (right to buy) M - Exercise D 8.85 -6,500 0
2013-09-13 2013-09-12 4 KAPLAN LESTER J PH D ACAD Stock option (right to buy) M - Exercise D 6.10 -50 4,450
2013-09-13 2013-09-12 4 KAPLAN LESTER J PH D ACAD Common Stock S - Sale D 22.9018 -66,356 -1,520 8,500
2013-09-13 2013-09-12 4 KAPLAN LESTER J PH D ACAD Common Stock M - Exercise D 2.1600 34,722 75 74,856
2013-09-13 2013-09-12 4 KAPLAN LESTER J PH D ACAD Common Stock M - Exercise D 2.1600 10,000 22 40,134
2013-09-13 2013-09-12 4 KAPLAN LESTER J PH D ACAD Common Stock M - Exercise D 9.0400 10,000 90 30,134
2013-09-13 2013-09-12 4 KAPLAN LESTER J PH D ACAD Common Stock M - Exercise D 8.8500 5,084 45 20,134
2013-09-13 2013-09-12 4 KAPLAN LESTER J PH D ACAD Common Stock M - Exercise D 8.8500 6,500 58 15,050
2013-09-13 2013-09-12 4 KAPLAN LESTER J PH D ACAD Common Stock M - Exercise D 6.1000 50 0 8,550
2013-09-13 2013-09-12 4 Iversen Leslie L ACAD Stock option (right to buy) M - Exercise D 1.30 -45,500 29,500
2013-09-13 2013-09-12 4 Iversen Leslie L ACAD Stock option (right to buy) M - Exercise D 1.30 -10,000 0
2013-09-13 2013-09-12 4 Iversen Leslie L ACAD Stock option (right to buy) M - Exercise D 6.10 -4,500 0
2013-09-13 2013-09-12 4 Iversen Leslie L ACAD Common Stock S - Sale D 22.9245 -60,000 -1,375 13,500
2013-09-13 2013-09-12 4 Iversen Leslie L ACAD Common Stock M - Exercise D 1.3000 45,500 59 73,500
2013-09-13 2013-09-12 4 Iversen Leslie L ACAD Common Stock M - Exercise D 1.3000 10,000 13 28,000
2013-09-13 2013-09-12 4 Iversen Leslie L ACAD Common Stock M - Exercise D 6.1000 4,500 27 18,000
2013-09-12 2013-09-10 4 Brege Laura ACAD Stock option (right to buy) M - Exercise D 1.30 -46,153 0
2013-09-12 2013-09-10 4 Brege Laura ACAD Common Stock S - Sale D 22.7969 -46,153 -1,052 0
2013-09-12 2013-09-10 4 Brege Laura ACAD Common Stock M - Exercise D 1.3000 46,153 60 46,153
2013-09-05 2013-09-03 4 Rasmussen Torsten ACAD Stock option (right to buy) M - Exercise I 1.30 -20,000 37,692
2013-09-05 2013-09-03 4 Rasmussen Torsten ACAD Stock option (right to buy) M - Exercise I 2.16 -10,000 0
2013-09-05 2013-09-03 4 Rasmussen Torsten ACAD Stock option (right to buy) M - Exercise I 1.30 -10,000 0
2013-09-05 2013-09-03 4 Rasmussen Torsten ACAD Common Stock S - Sale I 20.2775 -40,000 -811 8,500
2013-09-05 2013-09-03 4 Rasmussen Torsten ACAD Common Stock M - Exercise I 1.3000 20,000 26 48,500
2013-09-05 2013-09-03 4 Rasmussen Torsten ACAD Common Stock M - Exercise I 1.3000 10,000 13 28,500
2013-09-05 2013-09-03 4 Rasmussen Torsten ACAD Common Stock M - Exercise I 2.1600 10,000 22 18,500
2013-08-28 2013-08-26 4 GRAY MARY ANN ACAD Stock option (right to buy) M - Exercise D 8.49 -10,000 0
2013-08-28 2013-08-26 4 GRAY MARY ANN ACAD Stock option (right to buy) M - Exercise D 7.67 -5,000 1,500
2013-08-28 2013-08-26 4 GRAY MARY ANN ACAD Common Stock S - Sale D 20.7129 -10,000 -207 0
2013-08-28 2013-08-26 4 GRAY MARY ANN ACAD Common Stock S - Sale D 20.6164 -5,000 -103 10,000
2013-08-28 2013-08-26 4 GRAY MARY ANN ACAD Common Stock M - Exercise D 8.4900 10,000 85 15,000
2013-08-28 2013-08-26 4 GRAY MARY ANN ACAD Common Stock M - Exercise D 7.6700 5,000 38 5,000
2013-08-20 2013-08-19 4 Moore Terrence O ACAD Stock Option (right to buy) A - Award D 19.61 150,000 150,000
2013-08-15 2013-08-13 4 Hacksell Uli ACAD Stock Option (right to buy) M - Exercise D 1.08 -17,771 0
2013-08-15 2013-08-13 4 Hacksell Uli ACAD Stock Option (right to buy) M - Exercise D 1.08 -35,000 0
2013-08-15 2013-08-13 4 Hacksell Uli By Family Trust ACAD Common Stock S - Sale I 20.1448 -52,771 -1,063 109,049
2013-08-15 2013-08-13 4 Hacksell Uli By Family Trust ACAD Common Stock G - Gift I 52,771 161,820
2013-08-15 2013-08-13 4 Hacksell Uli ACAD Common Stock G - Gift D -52,771 0
2013-08-15 2013-08-13 4 Hacksell Uli ACAD Common Stock M - Exercise D 1.0800 17,771 19 52,771
2013-08-15 2013-08-13 4 Hacksell Uli ACAD Common Stock M - Exercise D 1.0800 35,000 38 35,000
2013-08-15 2013-08-13 4 Aasen Thomas H ACAD Stock Option (right to buy) M - Exercise D 1.55 -15,000 58,708
2013-08-15 2013-08-13 4 Aasen Thomas H ACAD Stock Option (right to buy) M - Exercise D 1.55 -30,000 82,263
2013-08-15 2013-08-13 4 Aasen Thomas H By Family Trust ACAD Common Stock S - Sale I 20.1530 -60,000 -1,209 0
2013-08-15 2013-08-13 4 Aasen Thomas H By Family Trust ACAD Common Stock G - Gift I 60,000 60,000
2013-08-15 2013-08-13 4 Aasen Thomas H ACAD Common Stock G - Gift D -60,000 31,585
2013-08-15 2013-08-13 4 Aasen Thomas H ACAD Common Stock M - Exercise D 1.5500 15,000 23 91,585
2013-08-15 2013-08-13 4 Aasen Thomas H ACAD Common Stock M - Exercise D 1.5500 30,000 46 76,585
2013-06-11 2013-06-07 4 KAPLAN LESTER J PH D ACAD Stock option (right to buy) A - Award D 17.01 12,500 12,500
2013-06-11 2013-06-07 4 BORER MICHAEL T ACAD Stock Option (right to buy) A - Award D 17.01 12,500 12,500
2013-06-11 2013-06-07 4 GRAY MARY ANN ACAD Stock option (right to buy) A - Award D 17.01 12,500 12,500
2013-06-11 2013-06-07 4 Iversen Leslie L ACAD Stock option (right to buy) A - Award D 17.01 14,000 14,000
2013-06-11 2013-06-07 4 Rasmussen Torsten ACAD Stock option (right to buy) A - Award I 17.01 12,500 12,500
2013-06-11 2013-06-07 4 Hacksell Uli ACAD Stock Option (right to buy) A - Award D 17.01 300,000 300,000
2013-06-11 2013-06-07 4 Aasen Thomas H ACAD Stock Option (right to buy) A - Award D 17.01 175,000 175,000
2013-06-11 2013-06-07 4 Brege Laura ACAD Stock option (right to buy) A - Award D 17.01 12,500 12,500
2013-06-11 2013-06-07 4 Mills Roger ACAD Stock Option (right to buy) A - Award D 17.01 175,000 175,000
2013-06-11 2013-06-07 4 Wells William McDowall ACAD Stock Option (right to buy) A - Award D 17.01 12,500 12,500
2013-06-11 2013-06-07 4 Baity Glenn ACAD Stock Option (right to buy) A - Award D 17.01 130,000 130,000
2013-06-11 2013-06-07 4 BAKER BROS. ADVISORS LP ACAD Non-Qualified Stock Option (right to buy) A - Award I 17.01 12,500 12,500
2013-06-11 2013-06-07 4 BAKER BROS. ADVISORS LP ACAD Non-Qualified Stock Option (right to buy) A - Award I 17.01 12,500 12,500
2013-06-11 2013-06-07 4 BAKER BROS. ADVISORS LP ACAD Non-Qualified Stock Option (right to buy) A - Award I 17.01 12,500 12,500
2013-06-05 2013-06-05 4 BAKER FELIX ACAD Common Stoc P - Purchase I 14.4641 5,437 79 440,802
2013-06-05 2013-06-05 4 BAKER FELIX ACAD Common Stoc P - Purchase I 14.4641 217,986 3,153 18,001,203
2013-06-05 2013-06-05 4 BAKER FELIX ACAD Common Stoc P - Purchase I 14.4641 26,577 384 1,513,121
2013-06-05 2013-06-05 4 BAKER FELIX ACAD Common Stoc P - Purchase I 14.5502 3,790 55 435,365
2013-06-05 2013-06-05 4 BAKER FELIX ACAD Common Stoc P - Purchase I 14.5502 151,980 2,211 17,783,217
2013-06-05 2013-06-05 4 BAKER FELIX ACAD Common Stoc P - Purchase I 14.5502 18,530 270 1,486,544
2013-06-05 2013-06-05 4 BAKER FELIX ACAD Common Stoc P - Purchase I 14.5838 4,312 63 431,575
2013-06-05 2013-06-05 4 BAKER FELIX ACAD Common Stoc P - Purchase I 14.5838 172,893 2,521 17,631,237
2013-06-05 2013-06-05 4 BAKER FELIX ACAD Common Stoc P - Purchase I 14.5838 21,080 307 1,468,014
2013-06-05 2013-06-05 4 BAKER FELIX ACAD Common Stoc P - Purchase I 14.4565 5,437 79 427,263
2013-06-05 2013-06-05 4 BAKER FELIX ACAD Common Stoc P - Purchase I 14.4565 217,986 3,151 17,458,344
2013-06-05 2013-06-05 4 BAKER FELIX ACAD Common Stoc P - Purchase I 14.4565 26,577 384 1,446,934
2013-06-05 2013-06-04 4 BAKER FELIX ACAD Common Stock P - Purchase I 14.4159 2,775 40 421,826
2013-06-05 2013-06-04 4 BAKER FELIX ACAD Common Stock P - Purchase I 14.4159 111,266 1,604 17,240,358
2013-06-05 2013-06-04 4 BAKER FELIX ACAD Common Stock P - Purchase I 14.4159 13,566 196 1,420,357
2013-06-05 2013-06-04 4 BAKER FELIX ACAD Common Stock P - Purchase I 14.4525 11,552 167 419,051
2013-06-05 2013-06-04 4 BAKER FELIX ACAD Common Stock P - Purchase I 14.4525 463,197 6,694 17,129,092
2013-06-05 2013-06-04 4 BAKER FELIX ACAD Common Stock P - Purchase I 14.4525 56,475 816 1,406,791
2013-06-05 2013-06-04 4 BAKER FELIX ACAD Common Stock P - Purchase I 14.4977 890 13 407,499
2013-06-05 2013-06-04 4 BAKER FELIX ACAD Common Stock P - Purchase I 14.4977 35,702 518 16,665,895
2013-06-05 2013-06-04 4 BAKER FELIX ACAD Common Stock P - Purchase I 14.4977 4,353 63 1,350,316
2013-06-05 2013-06-03 4 BAKER FELIX ACAD Common Stock P - Purchase I 13.9990 5,189 73 406,609
2013-06-05 2013-06-03 4 BAKER FELIX ACAD Common Stock P - Purchase I 13.9990 208,063 2,913 16,630,193
2013-06-05 2013-06-03 4 BAKER FELIX ACAD Common Stock P - Purchase I 13.9990 25,368 355 1,345,963
2013-06-05 2013-06-03 4 BAKER FELIX ACAD Common Stock P - Purchase I 14.0822 11,511 162 401,420
2013-06-05 2013-06-03 4 BAKER FELIX ACAD Common Stock P - Purchase I 14.0822 461,548 6,500 16,422,130
2013-06-05 2013-06-03 4 BAKER FELIX ACAD Common Stock P - Purchase I 14.0822 56,274 792 1,320,595
2013-05-17 2013-05-15 4 BAKER FELIX ACAD Common Stock P - Purchase I 12.5000 43,184 540 389,909
2013-05-17 2013-05-15 4 BAKER FELIX ACAD Common Stock P - Purchase I 12.5000 1,730,970 21,637 15,960,582
2013-05-17 2013-05-15 4 BAKER FELIX ACAD Common Stock P - Purchase I 12.5000 218,846 2,736 1,264,321
2013-05-03 2013-05-02 4 Hacksell Uli ACAD Stock Option (right to buy) M - Exercise D 1.08 -20,449 35,000
2013-05-03 2013-05-02 4 Hacksell Uli By Family Trust ACAD Common Stock S - Sale I 12.3427 -20,449 -252 109,049
2013-05-03 2013-05-02 4 Hacksell Uli By Family Trust ACAD Common Stock G - Gift I 20,449 129,498
2013-05-03 2013-05-02 4 Hacksell Uli ACAD Common Stock G - Gift D -20,449 0
2013-05-03 2013-05-02 4 Hacksell Uli ACAD Common Stock M - Exercise D 1.0800 20,449 22 20,449
2013-05-03 2013-05-01 4 Hacksell Uli ACAD Stock Option (right to buy) M - Exercise D 1.08 -19,551 55,449
2013-05-03 2013-05-01 4 Hacksell Uli By Family Trust ACAD Common Stock S - Sale I 12.7113 -19,551 -249 109,049
2013-05-03 2013-05-01 4 Hacksell Uli By Family Trust ACAD Common Stock G - Gift I 19,551 128,600
2013-05-03 2013-05-01 4 Hacksell Uli ACAD Common Stock G - Gift D -19,551 0
2013-05-03 2013-05-01 4 Hacksell Uli ACAD Common Stock M - Exercise D 1.0800 19,551 21 19,551
2013-04-24 2013-04-22 4 Baity Glenn ACAD Stock Option (right to buy) M - Exercise D 1.62 -10,000 22,407
2013-04-24 2013-04-22 4 Baity Glenn ACAD Common Stock S - Sale D 13.1493 -10,000 -131 40,000
2013-04-24 2013-04-22 4 Baity Glenn ACAD Common Stock M - Exercise D 1.6200 10,000 16 50,000
2013-04-17 2013-04-16 4 Hacksell Uli ACAD Stock Option (right to buy) M - Exercise D 1.08 -16,729 75,000
2013-04-17 2013-04-16 4 Hacksell Uli By Family Trust ACAD Common Stock S - Sale I 12.3168 -16,729 -206 109,049
2013-04-17 2013-04-16 4 Hacksell Uli By Family Trust ACAD Common Stock G - Gift I 16,729 125,778
2013-04-17 2013-04-16 4 Hacksell Uli ACAD Common Stock G - Gift D -16,729 0
2013-04-17 2013-04-16 4 Hacksell Uli ACAD Common Stock M - Exercise D 1.0800 16,729 18 16,729
2013-04-17 2013-04-17 4 Baity Glenn ACAD Stock Option (right to buy) M - Exercise D 1.55 -10,000 59,078
2013-04-17 2013-04-17 4 Baity Glenn ACAD Common Stock S - Sale D 12.2600 -10,000 -123 40,000
2013-04-17 2013-04-17 4 Baity Glenn ACAD Common Stock M - Exercise D 1.5500 10,000 16 50,000
2013-04-17 2013-04-16 4 Baity Glenn ACAD Stock Option (right to buy) M - Exercise D 1.55 -10,000 922
2013-04-17 2013-04-16 4 Baity Glenn ACAD Stock Option (right to buy) M - Exercise D 1.55 -10,000 922
2013-04-17 2013-04-16 4 Baity Glenn ACAD Common Stock S - Sale D 12.3000 -20,000 -246 40,000
2013-04-17 2013-04-16 4 Baity Glenn ACAD Common Stock M - Exercise D 1.5500 10,000 16 60,000
2013-04-17 2013-04-16 4 Baity Glenn ACAD Common Stock M - Exercise D 1.5500 10,000 16 60,000
2013-04-17 2013-04-15 4 Baity Glenn ACAD Stock Option (right to buy) M - Exercise D 1.55 -10,000 10,922
2013-04-17 2013-04-15 4 Baity Glenn ACAD Stock Option (right to buy) M - Exercise D 1.55 -10,000 10,922
2013-04-17 2013-04-15 4 Baity Glenn ACAD Common Stock S - Sale D 12.5000 -20,000 -250 40,000
2013-04-17 2013-04-15 4 Baity Glenn ACAD Common Stock M - Exercise D 1.5500 10,000 16 60,000
2013-04-17 2013-04-15 4 Baity Glenn ACAD Common Stock M - Exercise D 1.5500 10,000 16 60,000
2013-04-12 2013-04-11 4 Aasen Thomas H ACAD Stock Option (right to buy) M - Exercise D 1.55 -14,029 73,708
2013-04-12 2013-04-11 4 Aasen Thomas H ACAD Stock Option (right to buy) M - Exercise D 2.00 -12,500 0
2013-04-12 2013-04-11 4 Aasen Thomas H ACAD Stock Option (right to buy) M - Exercise D 1.08 -7,500 0
2013-04-12 2013-04-11 4 Aasen Thomas H By Family Trust ACAD Common Stock S - Sale I 11.0600 -40,000 -442 0
2013-04-12 2013-04-11 4 Aasen Thomas H By Family Trust ACAD Common Stock G - Gift I 40,000 40,000
2013-04-12 2013-04-11 4 Aasen Thomas H ACAD Common Stock G - Gift D -40,000 44,500
2013-04-12 2013-04-11 4 Aasen Thomas H ACAD Common Stock M - Exercise D 1.5500 14,029 22 84,500
2013-04-12 2013-04-11 4 Aasen Thomas H ACAD Common Stock M - Exercise D 2.0000 12,500 25 70,471
2013-04-12 2013-04-11 4 Aasen Thomas H ACAD Common Stock M - Exercise D 1.0800 7,500 8 57,971
2013-04-12 2013-04-12 4 Baity Glenn ACAD Stock Option (right to buy) M - Exercise D 1.62 -10,000 32,407
2013-04-12 2013-04-12 4 Baity Glenn ACAD Stock Option (right to buy) M - Exercise D 1.55 -10,000 32,407
2013-04-12 2013-04-12 4 Baity Glenn ACAD Stock Option (right to buy) M - Exercise D 1.55 -10,000 20,922
2013-04-12 2013-04-12 4 Baity Glenn ACAD Common Stock S - Sale D 13.0000 -10,000 -130 40,000
2013-04-12 2013-04-12 4 Baity Glenn ACAD Common Stock M - Exercise D 1.6200 10,000 16 50,000
2013-04-12 2013-04-12 4 Baity Glenn ACAD Common Stock S - Sale D 12.7400 -20,000 -255 40,000
2013-04-12 2013-04-12 4 Baity Glenn ACAD Common Stock M - Exercise D 1.5500 10,000 16 60,000
2013-04-12 2013-04-12 4 Baity Glenn ACAD Common Stock M - Exercise D 1.5500 10,000 16 60,000
2013-04-12 2013-04-11 4 Baity Glenn ACAD Stock Option (right to buy) M - Exercise D 1.55 -10,000 42,407
2013-04-12 2013-04-11 4 Baity Glenn ACAD Stock Option (right to buy) M - Exercise D 1.62 -10,000 42,407
2013-04-12 2013-04-11 4 Baity Glenn ACAD Stock Option (right to buy) M - Exercise D 1.55 -10,000 30,922
2013-04-12 2013-04-11 4 Baity Glenn ACAD Common Stock S - Sale D 13.0000 -10,000 -130 40,000
2013-04-12 2013-04-11 4 Baity Glenn ACAD Common Stock M - Exercise D 1.6200 10,000 16 50,000
2013-04-12 2013-04-11 4 Baity Glenn ACAD Common Stock S - Sale D 12.0000 -10,000 -120 40,000
2013-04-12 2013-04-11 4 Baity Glenn ACAD Common Stock M - Exercise D 1.5500 10,000 16 50,000
2013-04-12 2013-04-11 4 Baity Glenn ACAD Common Stock M - Exercise D 1.5500 10,000 16 50,000
2013-04-12 2013-04-11 4 Baity Glenn ACAD Common Stock S - Sale D 11.0600 -10,000 -111 40,000
2013-04-03 2013-04-01 4 Hacksell Uli ACAD Stock Option (right to buy) M - Exercise D 1.08 -40,000 91,729
2013-04-03 2013-04-01 4 Hacksell Uli By Family Trust ACAD Common Stock S - Sale I 7.6761 -40,000 -307 109,049
2013-04-03 2013-04-01 4 Hacksell Uli By Family Trust ACAD Common Stock G - Gift I 40,000 149,049
2013-04-03 2013-04-01 4 Hacksell Uli ACAD Common Stock G - Gift D -40,000 0
2013-04-03 2013-04-01 4 Hacksell Uli ACAD Common Stock M - Exercise D 1.0800 40,000 43 40,000
2013-04-03 2013-04-01 4 Aasen Thomas H ACAD Stock Option (right to buy) M - Exercise D 1.08 -36,490 7,500
2013-04-03 2013-04-01 4 Aasen Thomas H ACAD Stock Option (right to buy) M - Exercise D 1.08 -3,510 0
2013-04-03 2013-04-01 4 Aasen Thomas H By Family Trust ACAD Common Stock S - Sale I 7.6771 -40,000 -307 0
2013-04-03 2013-04-01 4 Aasen Thomas H By Family Trust ACAD Common Stock G - Gift I 40,000 40,000
2013-04-03 2013-04-01 4 Aasen Thomas H ACAD Common Stock G - Gift D -40,000 50,471
2013-04-03 2013-04-01 4 Aasen Thomas H ACAD Common Stock M - Exercise D 1.0800 36,490 39 90,471
2013-04-03 2013-04-01 4 Aasen Thomas H ACAD Common Stock M - Exercise D 1.0800 3,510 4 53,981
2013-04-03 2013-04-01 4 Mills Roger ACAD Common Stock S - Sale D 7.6875 -58,584 -450 14,017
2013-04-03 2013-04-02 4 Baity Glenn ACAD Common Stock S - Sale D 8.0000 -13,163 -105 40,000
2013-02-22 2013-02-21 4 Iversen Leslie L ACAD Stock option (right to buy) M - Exercise D 1.08 -4,500 0
2013-02-22 2013-02-21 4 Iversen Leslie L ACAD Common Stock M - Exercise D 4,500 13,500
2013-01-23 3 Baker Brothers Life Sciences LP ACAD Common Stock D 14,229,612
2013-01-23 3 14159, L.P. ACAD Common Stock D 346,725
2013-01-23 3 667, L.P. ACAD Common Stock D 1,045,475
2013-01-23 2013-01-18 4 BAKER FELIX ACAD Stock Options (right to buy) A - Award I 5.22 15,000 15,000
2013-01-18 2013-01-18 4 Hacksell Uli ACAD Stock Option (right to buy) M - Exercise D 1.08 -7,500 0
2013-01-18 2013-01-18 4 Hacksell Uli By Family Trust ACAD Common Stock G - Gift I 7,500 109,049
2013-01-18 2013-01-18 4 Hacksell Uli ACAD Common Stock G - Gift D -7,500 0
2013-01-18 2013-01-18 4 Hacksell Uli ACAD Common Stock M - Exercise D 7,500 7,500
2013-01-18 2013-01-17 4 Aasen Thomas H ACAD Stock Option (right to buy) M - Exercise D 1.08 -12,000 43,990
2013-01-18 2013-01-17 4 Aasen Thomas H ACAD Common Stock M - Exercise D 1.0800 12,000 13 50,471
2013-01-15 2013-01-14 4 KAPLAN LESTER J PH D ACAD Stock option (right to buy) M - Exercise D 1.08 -4,500 0
2013-01-15 2013-01-14 4 KAPLAN LESTER J PH D ACAD Common Stock M - Exercise D 1.0800 4,500 5 8,500
2013-01-10 2013-01-10 4 Rasmussen Torsten See footnote (1) ACAD Stock option (right to buy) M - Exercise I 1.08 -4,500 0
2013-01-10 2013-01-10 4 Rasmussen Torsten ACAD Common stock M - Exercise I 1.0800 4,500 5 8,500
2012-12-21 3 BAKER JULIAN See Footnotes ACAD Common Stock I 14,229,612
2012-12-21 3 BAKER JULIAN See Footnotes ACAD Common Stock I 1,045,475
2012-12-21 3 BAKER JULIAN See Footnotes ACAD Common Stock I 346,725
2012-11-29 2012-11-28 4 Aasen Thomas H ACAD Stock Option (right to buy) M - Exercise D 1.08 -5,000 3,510
2012-11-29 2012-11-28 4 Aasen Thomas H By Family Trust ACAD Common Stock S - Sale I 5.2499 -9,100 -48 0
2012-11-29 2012-11-28 4 Aasen Thomas H By Family Trust ACAD Common Stock G - Gift I 5,000 9,100
2012-11-29 2012-11-28 4 Aasen Thomas H ACAD Common Stock G - Gift D -5,000 28,471
2012-11-29 2012-11-28 4 Aasen Thomas H ACAD Common Stock M - Exercise D 1.0800 5,000 5 33,471
2012-11-29 2012-11-27 4 Aasen Thomas H By Family Trust ACAD Common Stock S - Sale I 6.2414 -30,900 -193 4,100
2012-11-29 2012-11-27 4 Aasen Thomas H By Family Trust ACAD Common Stock G - Gift I 33,631 35,000
2012-11-29 2012-11-27 4 Aasen Thomas H ACAD Common Stock G - Gift D -33,631 28,471
2012-11-29 2012-11-28 4 Baity Glenn ACAD Common Stock S - Sale D 5.2526 -4,396 -23 43,163
2012-11-29 2012-11-27 4 Baity Glenn ACAD Common Stock S - Sale D 6.2788 -16,206 -102 47,559
2012-09-11 2012-09-07 4 Aasen Thomas H ACAD Stock Option (right to buy) M - Exercise D 1.50 -7,500 20,000
2012-09-11 2012-09-07 4 Aasen Thomas H ACAD Common Stock M - Exercise D 1.5000 7,500 11 62,102
2012-08-22 2012-08-22 4 Hacksell Uli ACAD Stock Option (right to buy) M - Exercise D 1.50 -23,333 0
2012-08-22 2012-08-22 4 Hacksell Uli By Family Trust ACAD Common Stock G - Gift I 23,333 101,549
2012-08-22 2012-08-22 4 Hacksell Uli ACAD Common Stock G - Gift D -23,333 0
2012-08-22 2012-08-22 4 Hacksell Uli ACAD Common Stock M - Exercise D 23,333 23,333
2012-08-06 2012-08-03 4 Aasen Thomas H ACAD Stock Option (right to buy) M - Exercise D 1.50 -5,000 27,500
2012-08-06 2012-08-03 4 Aasen Thomas H ACAD Common Stock M - Exercise D 1.5000 5,000 8 54,602
2012-06-11 2012-06-08 4 KAPLAN LESTER J PH D ACAD Stock option (right to buy) A - Award D 1.36 55,147 55,147
2012-06-11 2012-06-08 4 KAPLAN LESTER J PH D ACAD Stock option (right to buy) A - Award D 1.36 10,000 10,000
2012-06-11 2012-06-08 4 BORER MICHAEL T ACAD Stock Option (right to buy) A - Award D 1.36 22,058 22,058
2012-06-11 2012-06-08 4 BORER MICHAEL T ACAD Stock Option (right to buy) A - Award D 1.36 10,000 10,000
2012-06-11 2012-06-08 4 GRAY MARY ANN ACAD Stock option (right to buy) A - Award D 1.36 55,147 55,147
2012-06-11 2012-06-08 4 GRAY MARY ANN ACAD Stock option (right to buy) A - Award D 1.36 10,000 10,000
2012-06-11 2012-06-08 4 Rasmussen Torsten ACAD Stock option (right to buy) A - Award I 1.36 10,000 10,000
2012-06-11 2012-06-08 4 Iversen Leslie L ACAD Stock option (right to buy) A - Award D 1.36 93,750 93,750
2012-06-11 2012-06-08 4 Iversen Leslie L ACAD Stock option (right to buy) A - Award D 1.36 10,000 10,000
2012-06-11 2012-06-08 4 Brege Laura ACAD Stock option (right to buy) A - Award D 1.36 44,117 44,117
2012-06-11 2012-06-08 4 Brege Laura ACAD Stock option (right to buy) A - Award D 1.36 10,000 10,000
2012-06-11 2012-06-08 4 Wells William McDowall ACAD Stock Option (right to buy) A - Award D 1.36 44,117 44,117
2012-06-11 2012-06-08 4 Wells William McDowall ACAD Stock Option (right to buy) A - Award D 1.36 10,000 10,000
2012-03-26 2012-03-23 4/A Baity Glenn ACAD Stock Option (right to buy) A - Award D 2.18 130,000 130,000
2012-03-26 2012-03-23 4/A Aasen Thomas H ACAD Stock Option (right to buy) A - Award D 2.18 175,000 175,000
2012-03-26 2012-03-23 4/A Mills Roger ACAD Stock Option (right to buy) A - Award D 2.18 175,000 175,000
2012-03-26 2012-03-23 4/A Hacksell Uli ACAD Stock Option (right to buy) A - Award D 2.18 300,000 300,000
2012-03-26 2012-03-23 4 Hacksell Uli ACAD Stock Option (right to buy) A - Award D 1.18 300,000 300,000
2012-03-26 2012-03-23 4 Aasen Thomas H ACAD Stock Option (right to buy) A - Award D 1.18 175,000 175,000
2012-03-26 2012-03-23 4 Mills Roger ACAD Stock Option (right to buy) A - Award D 1.18 175,000 175,000
2012-03-26 2012-03-23 4 Baity Glenn ACAD Stock Option (right to buy) A - Award D 1.18 130,000 130,000
2012-01-31 2012-01-27 4 Wells William McDowall ACAD Stock Option (right to buy) A - Award D 1.60 15,000 15,000
2010-03-16 3 Baity Glenn ACAD Common Stock D 30,203
2008-06-17 2008-06-13 4 WALTON ALAN G ACAD Stock Option (Right to Buy) A - Award D 8.49 8,833 8,833
2008-06-17 2008-06-13 4 WALTON ALAN G ACAD Stock Option (Right to Buy) A - Award D 8.49 10,000 10,000
2008-03-11 2008-03-07 4 Hacksell Uli ACAD Srock option (right to buy) A - Award D 8.32 60,000 60,000
2008-03-11 2008-03-07 4 Aasen Thomas H ACAD Stock option (right to buy) A - Award D 8.32 26,000 26,000
2008-03-11 2008-03-07 4 Tolf Bo-Ragnar ACAD Stock option (right to buy) A - Award D 8.32 21,000 21,000
2007-06-19 2007-06-15 4 WALTON ALAN G ACAD Stock Option (Right to Buy) A - Award D 15.02 3,994 3,994
2007-06-19 2007-06-15 4 WALTON ALAN G ACAD Stock Option (Right to Buy) A - Award D 15.02 10,000 10,000
2006-06-15 2006-06-13 4 WALTON ALAN G ACAD Stock Option (Right to Buy) A - Award D 9.04 16,637 16,637
2005-09-13 2005-09-09 4 WALTON ALAN G ACAD Stock Option (Right to Buy) A - Award D 11.00 8,500 8,500
2005-08-26 3 Nomura Phase4 Ventures LP Notes ACAD Common Stock, par value $0.0001 per share ("Common Stock") I 2,199,010
2005-08-02 2005-07-29 4 OXFORD BIOSCIENCE PARTNERS IV LP ACAD Common Stock Warrant (right to buy) P - Purchase D 8.15 3.0900 89,900 278 236,500
2005-06-14 2005-06-10 4 Binder Gordon M ACAD Stock Option (Right to Buy) A - Award D 8.85 6,500 6,500
2005-06-14 2005-06-10 4 KAPLAN LESTER J PH D ACAD Stock Option (Right to Buy) A - Award D 8.85 5,084 5,084
2005-06-14 2005-06-10 4 KAPLAN LESTER J PH D ACAD Stock Option (Right to Buy) A - Award D 8.85 6,500 6,500
2005-06-14 2005-06-10 4 Rasmussen Torsten Please see footnote. ACAD Stock Option (Right to Buy) A - Award I 8.85 2,542 2,542
2005-06-14 2005-06-10 4 Rasmussen Torsten Please see footnote. ACAD Stock Option (Right to Buy) A - Award I 8.85 6,500 6,500
2005-06-14 2005-06-09 4 Iversen Leslie L ACAD Stock Option (Right to Buy) A - Award D 8.85 7,627 7,627
2005-06-14 2005-06-09 4 Iversen Leslie L ACAD Stock Option (Right to Buy) A - Award D 8.85 6,500 6,500
2005-06-14 2005-06-10 4 WALTON ALAN G ACAD Stock Option (Right to Buy) A - Award D 8.85 5,084 5,084
2005-06-14 2005-06-10 4 WALTON ALAN G ACAD Stock Option (Right to Buy) A - Award D 8.85 6,500 6,500
2005-04-22 2005-04-20 4 GORDON CARL L ACAD Common Stock Warrant (Right to Buy) A - Award I 8.15 0.0313 89,900 3 89,900
2005-04-22 2005-04-20 4 GORDON CARL L ACAD Common Stock P - Purchase I 6.7900 359,603 2,442 774,006
2005-04-22 2005-04-20 4 van Osch Martien ACAD Common Stock Warrant (Right to Buy) A - Award I 8.15 0.0313 91,625 3 91,625
2005-04-22 2005-04-20 4 van Osch Martien ACAD Common Stock P - Purchase I 6.7900 366,501 2,489 1,168,892
2005-04-21 2005-04-20 4 OXFORD BIOSCIENCE PARTNERS IV LP ACAD Common Stock Warrant (right to buy) P - Purchase D 8.15 146,600 146,600
2005-04-21 2005-04-20 4 OXFORD BIOSCIENCE PARTNERS IV LP ACAD Common Stock P - Purchase D 6.8213 586,402 4,000 3,160,238
P
Pembelian sekuritas non-derivatif atau derivatif di pasar terbuka atau secara pribadi.
S
Penjualan terbuka atau penjualan pribadi atas sekuritas non-derivatif atau derivatif.
A
Hibah, penghargaan, atau perolehan sekuritas lainnya dari perusahaan (seperti opsi)
C
Konversi turunan
D
Penjualan atau pengalihan sekuritas kembali ke perusahaan.
F
Pembayaran harga pelaksanaan atau kewajiban pajak menggunakan sebagian sekuritas yang diterima dari perusahaan.
G
Pemberian sekuritas oleh atau kepada orang dalam.
K
Swap ekuitas dan transaksi lindung nilai serupa
M
Pelaksanaan atau konversi sekuritas derivatif yang diterima dari perusahaan (seperti opsi)
V
Transaksi yang dilaporkan secara sukarela pada Formulir 4.
J
Lainnya (disertai dengan catatan kaki yang menjelaskan transaksi tersebut)
Other Listings
DE:DR6 € 21.73
GB:0A4W
MX:ACAD
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