| Jumlah Saham Beredar | 201,622,825 shares |
| Saham Orang Dalam | 18,717,224 shares |
| Kepemilikan oleh Orang Dalam | 9.28 % |
| Orang Dalam Sejati | 61 |
Skor Sentimen Orang Dalam
Skor Sentimen Orang Dalam mengidentifikasi perusahaan yang dibeli oleh orang dalam korporat.
Ini adalah hasil dari model kuantitatif multifaktor yang canggih yang mengidentifikasi perusahaan dengan tingkat akumulasi internal tertinggi. Model penilaian ini menggunakan kombinasi dari jumlah bersih orang dalam yang membeli dalam 90 hari sebelumnya, total saham yang dibeli sebagai persentase dari jumlah saham yang beredar, dan total saham yang dimiliki oleh orang dalam. Angka tersebut berkisar dari 0 hingga 100, dengan angka yang lebih tinggi menunjukkan tingkat akumulasi yang lebih tinggi dibandingkan dengan perusahaan sejenis, dan 50 adalah rata-rata.
Frekuensi Pembaruan: Setiap Hari
Skor Sentimen Petugas
Skor Sentimen Pejabat menemukan perusahaan yang dibeli oleh Pejabat Korporat.
Menurut definisi, Pejabat Korporasi adalah Orang Dalam Korporasi, tetapi tidak seperti beberapa Orang Dalam lainnya (Pemegang Saham 10% dan Anggota Dewan), Pejabat bekerja untuk perusahaan setiap hari, dan mereka menggunakan uang mereka sendiri saat bertransaksi . (Pemegang Saham 10% dan Anggota Dewan seringkali adalah manajer dana yang mengelola uang orang lain.) Dengan demikian, transaksi orang dalam yang dilakukan oleh Pejabat jauh lebih signifikan dan harus ditangani dengan tepat.
Seperti Skor Sentimen Internal, Skor Sentimen Pejabat adalah hasil dari model kuantitatif multi-faktor yang canggih yang mengidentifikasi perusahaan dengan tingkat akumulasi pejabat tertinggi.
Frekuensi Pembaruan: Setiap Hari
Metrik Utama Orang Dalam
Kartu ini menunjukkan peringkat perusahaan berdasarkan berbagai metrik internal. Peringkat persentil menunjukkan bagaimana perusahaan ini dibandingkan dengan perusahaan lain di pasar AS. Peringkat yang lebih tinggi menunjukkan situasi yang lebih baik.
Sebagai contoh, secara umum diterima bahwa pembelian oleh orang dalam perusahaan adalah indikator positif, sehingga perusahaan dengan lebih banyak pembelian oleh orang dalam akan mendapat peringkat lebih tinggi daripada perusahaan dengan lebih sedikit pembelian oleh orang dalam (atau bahkan penjualan oleh orang dalam).
Jumlah Bersih Pembelian oleh Orang Dalam (Peringkat)
-3 ( )
10658 out of 11305Jumlah Bersih Pembelian oleh Orang Dalam adalah total jumlah orang dalam yang membeli dikurangi total jumlah orang dalam yang menjual dalam 90 hari terakhir. Peringkat persentil ditunjukkan di sini (kisaran dari 0 hingga 100%).
Persentase Saham yang Dibeli oleh Orang Dalam (Peringkat)
-0.023 %( )
10161 out of 11224Persentase Saham yang Dibeli oleh Orang Dalam adalah total jumlah saham yang dibeli oleh orang dalam dikurangi total jumlah saham yang dijual oleh orang dalam dalam 90 hari terakhir, dibagi dengan total jumlah saham yang beredar dan dikalikan dengan 100.
Grafik Perdagangan Orang Dalam
Grafik berikut menunjukkan Esperion Therapeutics, Inc. transaksi orang dalam. Orang dalam adalah pejabat, direktur, atau investor signifikan dalam suatu perusahaan. Secara umum, melakukan transaksi di perusahaan mereka berdasarkan informasi material yang belum dipublikasikan adalah ilegal bagi orang dalam. Ini tidak berarti bahwa mereka dilarang melakukan transaksi apa pun di perusahaan mereka sendiri. Namun, mereka wajib melaporkan semua transaksi kepada SEC melalui Formulir 4.
Daftar Orang Dalam dan Metrik Profitabilitas
Tabel ini menampilkan daftar orang dalam yang diketahui, dan dibuat secara otomatis dari pengajuan yang diungkapkan kepada SEC. Selain nama, jabatan terbaru, dan sebutan direktur, pejabat, atau pemilik 10%, kami memberikan kepemilikan terbaru yang diungkapkan. Selain itu, jika memungkinkan, kami memberikan kinerja perdagangan historis untuk orang dalam tersebut. Kinerja perdagangan historis adalah rata-rata tertimbang dari kinerja transaksi pembelian pasar terbuka aktual yang dilakukan oleh orang dalam tersebut. Untuk informasi lebih lanjut tentang bagaimana ini dihitung, tonton webinar YouTube ini.
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| Orang Dalam | Rata-rata Keuntungan (%) | Saham Dimiliki |
Terbagi Disesuaikan |
|---|---|---|---|
|
Aisling Capital Partners Llc
10% Owner -
|
1,837,125 | 1,837,125 | |
|
Aisling Capital Partners, Lp
10% Owner -
|
1,837,125 | 1,837,125 | |
|
Aisling Capital II LP
10% Owner -
|
1,837,125 | 1,837,125 | |
|
Alta Partners Management VIII, LLC
10% Owner -
|
2,552,189 | 2,552,189 | |
|
Alta Partners VIII, L.P.
10% Owner -
|
1,709,967 | 1,709,967 | |
|
Biotech Ag Bb
10% Owner -
|
4,477,964 | 4,477,964 | |
|
Target N V Biotech
10% Owner -
|
4,477,964 | 4,477,964 | |
|
James C Blair
10% Owner -
|
2,216,935 | 2,216,935 | |
| Richard Bartram Chief Financial Officer - [O] | 82,751 | 82,751 | |
| Jeffrey Berkowitz Director - [D] | 23,449 | 23,449 | |
|
Boxer Asset Management Inc.
10% Owner -
|
1,101,250 | 1,101,250 | |
|
Boxer Capital, LLC
10% Owner -
|
1,101,250 | 1,101,250 | |
|
Braslyn Ltd.
10% Owner -
|
2,602,450 | 2,602,450 | |
| Scott Braunstein Director - [D] | 5,019 | 5,019 | |
| J Martin Carroll Director - [D] | 97,650 | 97,650 | |
|
Farah Champsi
10% Owner -
|
2,552,189 | 2,552,189 | |
|
Associates Domain
10% Owner -
|
21,471 | 21,471 | |
|
Parters Vii L P Domain
10% Owner -
|
2,216,935 | 2,216,935 | |
|
Brian H Dovey
10% Owner -
|
2,216,935 | 2,216,935 | |
|
Dp Vii Associates Lp
10% Owner -
|
35,253 | 35,253 |
| Orang Dalam | Rata-rata Keuntungan (%) | Saham Dimiliki |
Terbagi Disesuaikan |
|---|---|---|---|
|
Steve Elms
10% Owner -
|
1,837,125 | 1,837,125 | |
| Patrick G Enright Director - [D] | 18,361 | 18,361 | |
| Fischer Seth H. Z. Director - [D] | 61,150 | 61,150 | |
| Foody Joanne M. Chief Medical Officer - [O] | 272,862 | 272,862 | |
| Alan Fuhrman Director - [D] | 53,404 | 53,404 | |
| Dov A Md Goldstein Director - [D] | 47 | 47 | |
| Antonio M Jr Md D Phil Gotto Director - [D] | 51,599 | 51,599 | |
| Mark A Glickman Chief Commercial Officer - [O] | 25,925 | 25,925 | |
| Robert Hoffman Director - [D] | 5,280 | 5,280 | |
|
Brian K Halak
10% Owner -
|
2,216,935 | 2,216,935 | |
| Ashley Hall Chief Development Officer - [O] | 22,500 | 22,500 | |
| Benjamin Halladay Chief Financial Officer - [O] | 474,462 | 474,462 | |
| Daniel Janney Director - [D] | 23,449 | 23,449 | |
|
Kamdar Kim P.
10% Owner -
|
21,471 | 21,471 | |
| Koenig Sheldon L. President and CEO, Director - [D] [O] | 1,541,488 | 1,541,488 | |
| Louis G Lange Director - [D] | 197,703 | 197,703 | |
|
Joseph Lewis
10% Owner -
|
1,101,250 | 1,101,250 | |
| Lalwani Narendra D. Chief Operating Officer - [O] | 5,000 | 5,000 | |
|
Longitude Capital Associates, L.P.
10% Owner -
|
28,186 | 28,186 | |
|
Longitude Capital Partners, LLC
10% Owner -
|
28,186 | 28,186 |
| Orang Dalam | Rata-rata Keuntungan (%) | Saham Dimiliki |
Terbagi Disesuaikan |
|---|---|---|---|
|
Longitude Venture Partners L.P.
10% Owner -
|
28,186 | 28,186 | |
| Benjamin Looker General Counsel - [O] | 399,937 | 399,937 | |
| Timothy M Mayleben President & CEO, Director - [D] [O] | 122,698 | 122,698 | |
| Mark E Mcgovern Director - [D] | 28,449 | 28,449 | |
| Mary McGowan Chief Medical Officer - [O] | 15,000 | 15,000 | |
| Roger S Newton Director - [D] | 548,726 | 548,726 | |
|
Guy P Nohra
10% Owner -
|
2,552,189 | 2,552,189 | |
| Gilbert S Omenn Director - [D] | 1,000 | 1,000 | |
|
Dennis J Purcell
10% Owner -
|
1,837,125 | 1,837,125 | |
| Stephen Rocamboli Director - [D] | 69,261 | 69,261 | |
| Rosenberg Noah L. | 13,500 | ||
|
Andrew N Schiff
10% Owner -
|
1,837,125 | 1,837,125 | |
|
Kathleen K Schoemaker
10% Owner -
|
2,216,935 | 2,216,935 | |
|
Nimesh Shah
10% Owner -
|
42,942 | 42,942 | |
| Jay Shepard Director - [D] | 84,599 | 84,599 | |
|
Jesse I Treu
10% Owner -
|
2,216,935 | 2,216,935 | |
|
Bakker Juliet Tammenoms
10% Owner -
|
28,186 | 28,186 | |
|
Tuesday Thirteen Inc.
10% Owner -
|
2,602,450 | 2,602,450 | |
|
Nicole Vitullo
Director, 10% Owner -
[D]
|
36,918 | 36,918 | |
| Eric Warren Chief Commercial Officer - [O] | 370,218 | 370,218 | |
| Tracy M Woody Director - [D] | 33,566 | 33,566 |
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Rekam Jejak Pembelian Orang Dalam - Analisis Keuntungan Jangka Pendek
Pada bagian ini, kami menganalisis profitabilitas setiap pembelian saham oleh orang dalam di pasar terbuka yang tidak direncanakan yang dilakukan di ESPR / Esperion Therapeutics, Inc.. Analisis ini membantu memahami apakah orang dalam tersebut secara konsisten menghasilkan pengembalian abnormal, dan layak untuk diikuti. Analisis ini dilakukan selama satu tahun setelah setiap transaksi, dan hasilnya bersifat teoretis .
Tabel berikut menunjukkan pembelian pasar terbuka terbaru yang bukan bagian dari rencana perdagangan otomatis.
Harga yang Disesuaikan adalah harga yang disesuaikan dengan pemisahan saham. Ang Adjusted Shares ay ang jumlah saham yang disesuaikan dengan pemisahan saham (stock split).
Rekam Jejak Penjualan Orang Dalam - Analisis Kerugian Jangka Pendek
Dalam bagian ini, kami menganalisis penghindaran kerugian jangka pendek dari setiap penjualan dalam pasar terbuka yang tidak direncanakan oleh orang dalam yang dilakukan di ESPR / Esperion Therapeutics, Inc.. Pola penghindaran kerugian yang konsisten dapat menunjukkan bahwa transaksi penjualan di masa mendatang dapat memprediksi penurunan harga. Analisis ini berlaku untuk satu tahun setelah setiap perdagangan, dan hasilnya bersifat teoretis .
Tabel berikut menunjukkan penjualan pasar terbuka terbaru yang bukan bagian dari rencana perdagangan otomatis.
Harga yang Disesuaikan adalah harga yang disesuaikan dengan pemisahan saham. Ang Adjusted Shares ay ang jumlah saham yang disesuaikan dengan pemisahan saham (stock split).
Riwayat Transaksi
Klik ikon tautan untuk melihat riwayat transaksi lengkap. Transaksi yang dilaporkan sebagai bagian dari rencana perdagangan otomatis 10b5-1 akan memiliki tanda X di kolom yang bertanda 10b-5.
| Berkas Tanggal |
Perdagangan Tanggal |
Formulir | Orang Dalam | Ticker | Judul Keamanan | Kode | Langsung | Latihan Harga |
Satuan Harga |
Unit Diubah |
Nilai Diubah (1 ribu) |
Sisa Pilihan |
Sisa Saham |
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2025-07-18 | 2025-07-17 | 4 | Looker Benjamin | ESPR | Common Stock | D | 1.1270 | -1,304 | -1 | 399,937 | ||||
| 2025-07-18 | 2025-07-17 | 4 | Halladay Benjamin | ESPR | Common Stock | D | 1.1150 | -11 | -0 | 474,462 | ||||
| 2025-06-18 | 2025-06-17 | 4 | Koenig Sheldon L. | ESPR | Common Stock | D | 1.1090 | -30,474 | -34 | 1,541,488 | ||||
| 2025-06-18 | 2025-06-17 | 4 | Looker Benjamin | ESPR | Common Stock | D | 1.1520 | -6,422 | -7 | 401,241 | ||||
| 2025-06-18 | 2025-06-17 | 4 | Halladay Benjamin | ESPR | Common Stock | D | 1.1520 | -7,229 | -8 | 474,473 | ||||
| 2025-06-02 | 2025-05-29 | 4 | CARROLL J MARTIN | ESPR | Common Stock | D | 33,000 | 97,650 | ||||||
| 2025-06-02 | 2025-05-29 | 4 | HOFFMAN ROBERT | ESPR | Common Stock | D | 5,280 | 5,280 | ||||||
| 2025-06-02 | 2025-05-29 | 4 | Fischer Seth H. Z. | ESPR | Common Stock | D | 33,000 | 61,150 | ||||||
| 2025-06-02 | 2025-05-29 | 4 | ROCAMBOLI STEPHEN | ESPR | Common Stock | D | 33,000 | 69,261 | ||||||
| 2025-06-02 | 2025-05-29 | 4 | Shepard Jay | ESPR | Common Stock | D | 33,000 | 84,599 | ||||||
| 2025-04-21 | 2025-04-17 | 4 | Halladay Benjamin | ESPR | Common Stock | D | 0.9640 | -8 | -0 | 481,702 | ||||
| 2025-04-21 | 2025-04-17 | 4 | Warren Eric | ESPR | Common Stock | D | 0.9780 | -108 | -0 | 370,218 | ||||
| 2025-03-19 | 2025-03-18 | 4 | Warren Eric | ESPR | Common Stock | D | 1.4870 | -2,433 | -4 | 370,326 | ||||
| 2025-03-19 | 2025-03-18 | 4 | Halladay Benjamin | ESPR | Common Stock | D | 1.4830 | -3,535 | -5 | 481,710 | ||||
| 2025-03-19 | 2025-03-18 | 4 | Koenig Sheldon L. | ESPR | Common Stock | D | 1.5040 | -13,047 | -20 | 1,571,962 | ||||
| 2025-03-17 | 2025-03-14 | 4 | Koenig Sheldon L. | ESPR | Common Stock | D | 840,000 | 1,585,009 | ||||||
| 2025-03-17 | 2025-03-14 | 4 | Halladay Benjamin | ESPR | Common Stock | D | 238,000 | 485,245 | ||||||
| 2025-03-17 | 2025-03-14 | 4 | Looker Benjamin | ESPR | Common Stock | D | 224,000 | 407,663 | ||||||
| 2025-03-17 | 2025-03-14 | 4 | Warren Eric | ESPR | Common Stock | D | 213,000 | 372,759 | ||||||
| 2025-02-20 | 2025-02-19 | 4 | Halladay Benjamin | ESPR | Common Stock | D | 1.8600 | -11 | -0 | 240,671 | ||||
| 2025-02-20 | 2025-02-19 | 4 | Warren Eric | ESPR | Common Stock | D | 1.8680 | -239 | -0 | 159,759 | ||||
| 2025-01-21 | 2025-01-17 | 4 | Halladay Benjamin | ESPR | Common Stock | D | 2.2650 | -9 | -0 | 240,682 | ||||
| 2025-01-21 | 2025-01-17 | 4 | Warren Eric | ESPR | Common Stock | D | 2.2600 | -123 | -0 | 159,998 | ||||
| 2024-12-18 | 2024-12-17 | 4 | Halladay Benjamin | ESPR | Common Stock | D | 2.4240 | -3,245 | -8 | 240,691 | ||||
| 2024-12-18 | 2024-12-17 | 4 | Warren Eric | ESPR | Common Stock | D | 2.4290 | -2,234 | -5 | 160,121 | ||||
| 2024-12-18 | 2024-12-17 | 4 | Koenig Sheldon L. | ESPR | Common Stock | D | 2.4660 | -12,447 | -31 | 739,819 | ||||
| 2024-11-20 | 2024-11-19 | 4 | Warren Eric | ESPR | Common Stock | D | 2.1650 | -197 | -0 | 162,355 | ||||
| 2024-10-18 | 2024-10-17 | 4 | Warren Eric | ESPR | Common Stock | D | 2.1190 | -107 | -0 | 162,552 | ||||
| 2024-09-18 | 2024-09-17 | 4 | Koenig Sheldon L. | ESPR | Common Stock | D | 1.7960 | -14,550 | -26 | 752,266 | ||||
| 2024-09-18 | 2024-09-17 | 4 | Warren Eric | ESPR | Common Stock | D | 1.7830 | -2,608 | -5 | 162,659 | ||||
| 2024-08-20 | 2024-08-19 | 4 | Warren Eric | ESPR | Common Stock | D | 1.9460 | -211 | -0 | 165,267 | ||||
| 2024-07-19 | 2024-07-17 | 4 | Foody Joanne M. | ESPR | Common Stock | D | 2.5990 | -917 | -2 | 272,862 | ||||
| 2024-07-19 | 2024-07-17 | 4 | Warren Eric | ESPR | Common Stock | D | 2.5870 | -108 | -0 | 165,478 | ||||
| 2024-06-20 | 2024-06-18 | 4 | Foody Joanne M. | ESPR | Common Stock | D | 2.8670 | -3,285 | -9 | 273,779 | ||||
| 2024-06-20 | 2024-06-18 | 4 | Warren Eric | ESPR | Common Stock | D | 2.8560 | -2,540 | -7 | 165,586 | ||||
| 2024-05-24 | 2024-05-23 | 4 | CARROLL J MARTIN | ESPR | Common Stock | D | 23,000 | 64,650 | ||||||
| 2024-05-24 | 2024-05-23 | 4 | Fischer Seth H. Z. | ESPR | Common Stock | D | 23,000 | 28,150 | ||||||
| 2024-05-24 | 2024-05-23 | 4 | Fuhrman Alan | ESPR | Common Stock | D | 23,000 | 53,404 | ||||||
| 2024-05-24 | 2024-05-23 | 4 | ROCAMBOLI STEPHEN | ESPR | Common Stock | D | 23,000 | 36,261 | ||||||
| 2024-05-24 | 2024-05-23 | 4 | GOTTO ANTONIO M JR MD D PHIL | ESPR | Common Stock | D | 23,000 | 51,599 | ||||||
| 2024-05-24 | 2024-05-23 | 4 | Shepard Jay | ESPR | Common Stock | D | 23,000 | 51,599 | ||||||
| 2024-05-20 | 2024-05-17 | 4 | Warren Eric | ESPR | Common Stock | D | 2.4830 | -192 | -0 | 168,126 | ||||
| 2024-03-15 | 2024-03-14 | 4 | Warren Eric | ESPR | Common Stock | D | 100,000 | 168,318 | ||||||
| 2024-03-15 | 2024-03-14 | 4 | Koenig Sheldon L. | ESPR | Common Stock | D | 454,000 | 766,816 | ||||||
| 2024-03-15 | 2024-03-14 | 4 | Looker Benjamin | ESPR | Common Stock | D | 100,000 | 183,663 | ||||||
| 2024-03-15 | 2024-03-14 | 4 | Foody Joanne M. | ESPR | Common Stock | D | 150,000 | 277,064 | ||||||
| 2024-03-15 | 2024-03-14 | 4 | Halladay Benjamin | ESPR | Common Stock | D | 170,000 | 243,936 | ||||||
| 2023-09-21 | 2023-09-20 | 4 | Warren Eric | ESPR | Common Stock | D | 1.2450 | -742 | -1 | 68,318 | ||||
| 2023-08-21 | 2023-08-18 | 4 | Warren Eric | ESPR | Common Stock | D | 1.4140 | -243 | -0 | 69,060 | ||||
| 2023-07-20 | 2023-07-19 | 4 | Warren Eric | ESPR | Common Stock | D | 1.5850 | -106 | -0 | 69,303 | ||||
| 2023-06-22 | 2023-06-21 | 4 | Warren Eric | ESPR | Common Stock | D | 1.4830 | -603 | -1 | 69,409 | ||||
| 2023-06-16 | 2023-06-15 | 4 | Fuhrman Alan | ESPR | Common Stock | D | 5,150 | 30,404 | ||||||
| 2023-06-16 | 2023-06-15 | 4 | CARROLL J MARTIN | ESPR | Common Stock | D | 5,150 | 41,650 | ||||||
| 2023-06-16 | 2023-06-15 | 4 | Fischer Seth H. Z. | ESPR | Common Stock | D | 5,150 | 5,150 | ||||||
| 2023-06-16 | 2023-06-15 | 4 | Woody Tracy M | ESPR | Common Stock | D | 5,150 | 33,566 | ||||||
| 2023-06-16 | 2023-06-15 | 4 | ROCAMBOLI STEPHEN | ESPR | Common Stock | D | 5,150 | 13,261 | ||||||
| 2023-06-16 | 2023-06-15 | 4 | Shepard Jay | ESPR | Common Stock | D | 5,150 | 28,599 | ||||||
| 2023-06-16 | 2023-06-15 | 4 | VITULLO NICOLE | ESPR | Common Stock | D | 5,150 | 36,918 | ||||||
| 2023-06-16 | 2023-06-15 | 4 | GOTTO ANTONIO M JR MD D PHIL | ESPR | Common Stock | D | 5,150 | 28,599 | ||||||
| 2023-05-18 | 2023-05-17 | 4 | Warren Eric | ESPR | Common Stock | D | 1.6240 | -219 | -0 | 70,012 | ||||
| 2023-05-11 | 2023-05-11 | 4 | CARROLL J MARTIN | ESPR | Common Stock | D | 1.5714 | 23,091 | 36 | 36,500 | ||||
| 2023-05-11 | 2023-05-10 | 4 | CARROLL J MARTIN | ESPR | Common Stock | D | 1.4919 | 8,409 | 13 | 13,409 | ||||
| 2023-05-11 | 2023-05-10 | 4 | ROCAMBOLI STEPHEN | ESPR | Common Stock | D | 1.4950 | 8,111 | 12 | 8,111 | ||||
| 2023-05-10 | 2023-05-09 | 4 | Koenig Sheldon L. | ESPR | Common Stock | D | 1.2596 | 20,000 | 25 | 312,816 | ||||
| 2023-04-20 | 2023-04-19 | 4 | Warren Eric | ESPR | Common Stock | D | 1.2780 | -115 | -0 | 70,231 | ||||
| 2023-04-20 | 2023-04-19 | 4 | Looker Benjamin | ESPR | Common Stock | D | 1.2720 | -1,290 | -2 | 83,663 | ||||
| 2023-04-20 | 2023-04-19 | 4 | Foody Joanne M. | ESPR | Common Stock | D | 1.2710 | -938 | -1 | 127,064 | ||||
| 2023-03-20 | 2023-03-17 | 4 | Foody Joanne M. | ESPR | Common Stock | D | 1.7819 | -3,808 | -7 | 128,002 | ||||
| 2023-03-20 | 2023-03-17 | 4 | Warren Eric | ESPR | Common Stock | D | 1.7823 | -526 | -1 | 70,346 | ||||
| 2023-03-20 | 2023-03-17 | 4 | Koenig Sheldon L. | ESPR | Common Stock | D | 1.7830 | -6,999 | -12 | 292,816 | ||||
| 2023-03-15 | 2023-03-14 | 4 | Koenig Sheldon L. | ESPR | Common Stock | D | 105,000 | 299,815 | ||||||
| 2023-03-15 | 2023-03-14 | 4 | Warren Eric | ESPR | Common Stock | D | 22,300 | 70,872 | ||||||
| 2023-03-15 | 2023-03-14 | 4 | Looker Benjamin | ESPR | Common Stock | D | 20,500 | 84,953 | ||||||
| 2023-03-15 | 2023-03-14 | 4 | Foody Joanne M. | ESPR | Common Stock | D | 28,750 | 131,810 | ||||||
| 2023-03-15 | 2023-03-14 | 4 | Halladay Benjamin | ESPR | Common Stock | D | 9,200 | 73,936 | ||||||
| 2023-03-08 | 2023-03-07 | 4 | Warren Eric | ESPR | Common Stock | D | 5.0550 | -5,090 | -26 | 48,572 | ||||
| 2023-03-08 | 2023-03-07 | 4 | Foody Joanne M. | ESPR | Common Stock | D | 5.0650 | -3,884 | -20 | 103,060 | ||||
| 2023-03-08 | 2023-03-07 | 4 | Koenig Sheldon L. | ESPR | Common Stock | D | 5.0560 | -5,441 | -28 | 194,815 | ||||
| 2023-01-19 | 2023-01-18 | 4 | Looker Benjamin | ESPR | Common Stock | D | 6.9960 | -6,347 | -44 | 64,453 | ||||
| 2023-01-19 | 2023-01-18 | 4 | Foody Joanne M. | ESPR | Common Stock | D | 6.9850 | -1,191 | -8 | 106,944 | ||||
| 2022-12-12 | 2022-12-09 | 4 | Halladay Benjamin | ESPR | Common Stock | D | 44,000 | 63,771 | ||||||
| 2022-11-16 | 3 | Halladay Benjamin | ESPR | Common Stock | D | 19,771 | ||||||||
| 2022-10-19 | 2022-10-18 | 4 | Foody Joanne M. | ESPR | Common Stock | D | 7.6880 | -942 | -7 | 108,135 | ||||
| 2022-10-19 | 2022-10-18 | 4 | Warren Eric | ESPR | Common Stock | D | 7.6900 | -107 | -1 | 53,662 | ||||
| 2022-09-20 | 2022-09-19 | 4 | Warren Eric | ESPR | Common Stock | D | 6.9210 | -255 | -2 | 53,769 | ||||
| 2022-09-20 | 2022-09-19 | 4 | Koenig Sheldon L. | ESPR | Common Stock | D | 6.9380 | -3,394 | -24 | 198,257 | ||||
| 2022-08-31 | 2022-08-31 | 4 | Warren Eric | ESPR | Common Stock | D | 7.4600 | 1,000 | 7 | 54,024 | ||||
| 2022-08-18 | 2022-08-17 | 4 | Warren Eric | ESPR | Common Stock | D | 6.8150 | -199 | -1 | 53,024 | ||||
| 2022-08-08 | 2022-08-05 | 4 | Koenig Sheldon L. | ESPR | Common Stock | D | 5.8041 | 8,606 | 50 | 198,771 | ||||
| 2022-07-20 | 2022-07-19 | 4 | Warren Eric | ESPR | Common Stock | D | 6.5820 | -431 | -3 | 53,223 | ||||
| 2022-07-20 | 2022-07-19 | 4 | Foody Joanne M. | ESPR | Common Stock | D | 6.5500 | -3,901 | -26 | 109,077 | ||||
| 2022-06-21 | 2022-06-17 | 4 | Koenig Sheldon L. | ESPR | Common Stock | D | 4.9910 | -4,552 | -23 | 190,165 | ||||
| 2022-06-21 | 2022-06-17 | 4 | Warren Eric | ESPR | Common Stock | D | 4.9000 | -256 | -1 | 53,654 | ||||
| 2022-06-03 | 2022-06-02 | 4 | CARROLL J MARTIN | ESPR | Common Stock | D | 5.6359 | 5,000 | 28 | 5,000 | ||||
| 2022-05-27 | 2022-05-26 | 4 | Woody Tracy M | ESPR | Stock Option (right to buy) | D | 5.51 | 20,000 | 20,000 | |||||
| 2022-05-27 | 2022-05-26 | 4 | Berkowitz Jeffrey | ESPR | Stock Option (right to buy) | D | 5.51 | 20,000 | 20,000 | |||||
| 2022-05-27 | 2022-05-26 | 4 | Fischer Seth H. Z. | ESPR | Stock Option (right to buy | D | 5.51 | 11,561 | 11,561 | |||||
| 2022-05-27 | 2022-05-26 | 4 | Fuhrman Alan | ESPR | Stock Option (right to buy) | D | 5.51 | 20,000 | 20,000 | |||||
| 2022-05-27 | 2022-05-26 | 4 | ROCAMBOLI STEPHEN | ESPR | Stock Option (right to buy) | D | 5.51 | 1,589 | 1,589 | |||||
| 2022-05-27 | 2022-05-26 | 4 | ROCAMBOLI STEPHEN | ESPR | Stock Option (right to buy) | D | 5.51 | 40,000 | 40,000 | |||||
| 2022-05-27 | 2022-05-26 | 4 | VITULLO NICOLE | ESPR | Stock Option (right to buy) | D | 5.51 | 20,000 | 20,000 | |||||
| 2022-05-27 | 2022-05-26 | 4 | Shepard Jay | ESPR | Stock Option (right to buy) | D | 5.51 | 20,000 | 20,000 | |||||
| 2022-05-27 | 2022-05-26 | 4 | GOTTO ANTONIO M JR MD D PHIL | ESPR | Stock Option (right to buy) | D | 5.51 | 20,000 | 20,000 | |||||
| 2022-05-18 | 2022-05-17 | 4 | Warren Eric | ESPR | Common Stock | D | 5.9810 | -196 | -1 | 53,910 | ||||
| 2022-03-18 | 2022-03-17 | 4 | Koenig Sheldon L. | ESPR | Common Stock | D | 4.5800 | -571 | -3 | 194,717 | ||||
| 2022-03-16 | 2022-03-14 | 4 | Warren Eric | ESPR | Common Stock | D | 13,000 | 54,106 | ||||||
| 2022-03-16 | 2022-03-14 | 4 | Foody Joanne M. | ESPR | Common Stock | D | 28,000 | 112,978 | ||||||
| 2022-03-16 | 2022-03-14 | 4 | Koenig Sheldon L. | ESPR | Common Stock | D | 116,000 | 195,288 | ||||||
| 2022-03-16 | 2022-03-14 | 4 | Bartram Richard | ESPR | Common Stock | D | 37,000 | 82,751 | ||||||
| 2022-03-09 | 3 | Warren Eric | ESPR | Common Stock | D | 24,000 | ||||||||
| 2022-03-09 | 3 | Warren Eric | ESPR | Common Stock | D | 5,899 | ||||||||
| 2022-03-09 | 3 | Warren Eric | ESPR | Common Stock | D | 11,207 | ||||||||
| 2022-01-28 | 2022-01-27 | 4 | Looker Benjamin | ESPR | Stock Option (right to buy) | D | 3.65 | 100,450 | 100,450 | |||||
| 2022-01-28 | 2022-01-27 | 4 | Looker Benjamin | ESPR | Common Stock | D | 70,800 | 70,800 | ||||||
| 2021-11-01 | 2021-10-29 | 4 | Koenig Sheldon L. | ESPR | Common Stock | D | 26,700 | 76,700 | ||||||
| 2021-11-01 | 2021-10-29 | 4 | Foody Joanne M. | ESPR | Common Stock | D | 22,450 | 84,978 | ||||||
| 2021-11-01 | 2021-10-29 | 4 | Bartram Richard | ESPR | Common Stock | D | 18,700 | 43,852 | ||||||
| 2021-07-08 | 2021-06-28 | 4 | Foody Joanne M. | ESPR | Stock Option (right to buy) | D | 22.52 | 88,692 | 88,692 | |||||
| 2021-07-08 | 2021-06-28 | 4 | Foody Joanne M. | ESPR | Common Stock | D | 62,528 | 62,528 | ||||||
| 2021-06-30 | 2021-06-28 | 4 | Bartram Richard | ESPR | Performance-based Restricted Stock Units | D | 26,400 | 26,400 | ||||||
| 2021-06-30 | 2021-06-28 | 4 | Bartram Richard | ESPR | Stock Option (right to buy) | D | 22.52 | 37,500 | 37,500 | |||||
| 2021-05-28 | 2021-05-27 | 4 | MCGOVERN MARK E | ESPR | Common Stock | D | 12,376 | 28,449 | ||||||
| 2021-05-28 | 2021-05-27 | 4 | Fuhrman Alan | ESPR | Common Stock | D | 12,376 | 25,254 | ||||||
| 2021-05-28 | 2021-05-27 | 4 | Berkowitz Jeffrey | ESPR | Common Stock | D | 12,376 | 23,449 | ||||||
| 2021-05-28 | 2021-05-27 | 4 | GOTTO ANTONIO M JR MD D PHIL | ESPR | Common Stock | D | 12,376 | 23,449 | ||||||
| 2021-05-28 | 2021-05-27 | 4 | Shepard Jay | ESPR | Common Stock | D | 12,376 | 23,449 | ||||||
| 2021-05-28 | 2021-05-27 | 4 | Woody Tracy M | ESPR | Common Stock | D | 12,376 | 28,416 | ||||||
| 2021-05-28 | 2021-05-27 | 4 | JANNEY DANIEL | ESPR | Common Stock | D | 12,376 | 23,449 | ||||||
| 2021-05-28 | 2021-05-27 | 4 | VITULLO NICOLE | ESPR | Common Stock | D | 12,376 | 31,768 | ||||||
| 2021-05-26 | 2021-05-24 | 4 | BIOTECH TARGET N V | ESPR | Common Stock | D | 20.2162 | 100,000 | 2,022 | 4,477,964 | ||||
| 2021-05-21 | 2021-05-19 | 4 | BIOTECH TARGET N V | ESPR | Common Stock | D | 20.3698 | 200,000 | 4,074 | 4,377,964 | ||||
| 2021-05-18 | 2021-05-17 | 4 | Koenig Sheldon L. | ESPR | Stock Option (right to buy) | D | 20.87 | 120,000 | 120,000 | |||||
| 2021-05-18 | 2021-05-17 | 4 | Koenig Sheldon L. | ESPR | Common Stock | D | 20,000 | 50,000 | ||||||
| 2021-05-07 | 2021-05-06 | 4 | BIOTECH TARGET N V | ESPR | Common Stock | D | 20.5704 | 80,000 | 1,646 | 4,177,964 | ||||
| 2021-05-07 | 2021-05-05 | 4 | BIOTECH TARGET N V | ESPR | Common Stock | D | 20.0190 | 150,000 | 3,003 | 4,097,964 | ||||
| 2021-01-29 | 2021-01-28 | 4 | Hall Ashley | ESPR | Stock Option (right to buy) | D | 32.12 | 31,000 | 31,000 | |||||
| 2021-01-29 | 2021-01-28 | 4 | Hall Ashley | ESPR | Common Stock | D | 7,000 | 22,500 | ||||||
| 2021-01-29 | 2021-01-28 | 4 | Bartram Richard | ESPR | Stock Option (right to buy) | D | 32.12 | 50,000 | 50,000 | |||||
| 2021-01-29 | 2021-01-28 | 4 | Bartram Richard | ESPR | Common Stock | D | 5,000 | 23,617 | ||||||
| 2021-01-29 | 2021-01-28 | 4 | MAYLEBEN TIMOTHY M | ESPR | Stock Option (right to buy) | D | 32.12 | 175,000 | 175,000 | |||||
| 2021-01-29 | 2021-01-28 | 4 | Koenig Sheldon L. | ESPR | Stock Option (right to buy) | D | 32.12 | 150,000 | 150,000 | |||||
| 2021-01-29 | 2021-01-28 | 4 | Koenig Sheldon L. | ESPR | Common Stock | D | 30,000 | 30,000 | ||||||
| 2020-12-31 | 2020-12-30 | 4 | MAYLEBEN TIMOTHY M | ESPR | Stock Option (right to buy) | D | 2.10 | -10,700 | 262,959 | |||||
| 2020-12-31 | 2020-12-30 | 4 | MAYLEBEN TIMOTHY M | ESPR | Common Stock | D | 2.0960 | 10,700 | 22 | 122,698 | ||||
| 2020-11-04 | 2020-11-03 | 4 | BIOTECH TARGET N V | ESPR | Common Stock | D | 25.3106 | 200,000 | 5,062 | 3,947,964 | ||||
| 2020-05-29 | 2020-05-28 | 4 | Woody Tracy M | ESPR | Common Stock | D | 6,106 | 16,040 | ||||||
| 2020-05-29 | 2020-05-28 | 4 | VITULLO NICOLE | ESPR | Common Stock | D | 6,106 | 19,392 | ||||||
| 2020-05-29 | 2020-05-28 | 4 | Shepard Jay | ESPR | Common Stock | D | 6,106 | 11,073 | ||||||
| 2020-05-29 | 2020-05-28 | 4 | MCGOVERN MARK E | ESPR | Common Stock | D | 6,106 | 16,073 | ||||||
| 2020-05-29 | 2020-05-28 | 4 | JANNEY DANIEL | ESPR | Common Stock | D | 6,106 | 11,073 | ||||||
| 2020-05-29 | 2018-02-28 | 4 | JANNEY DANIEL By Alta Bioequities, L.P. | ESPR | Common Stock | I | 24,565 | 24,565 | ||||||
| 2020-05-29 | 2020-05-28 | 4 | GOTTO ANTONIO M JR MD D PHIL | ESPR | Common Stock | D | 6,106 | 11,073 | ||||||
| 2020-05-29 | 2020-05-28 | 4 | Fuhrman Alan | ESPR | Common Stock | D | 1,221 | 12,878 | ||||||
| 2020-05-29 | 2020-05-28 | 4 | Berkowitz Jeffrey | ESPR | Common Stock | D | 6,106 | 11,073 | ||||||
| 2020-05-18 | 2020-05-15 | 4 | Fuhrman Alan | ESPR | Common Stock | D | 11,003 | 11,657 | ||||||
| 2020-03-18 | 3 | Fuhrman Alan | ESPR | Common Stock | D | 1,308 | ||||||||
| 2020-03-18 | 3 | Fuhrman Alan | ESPR | Common Stock | D | 1,308 | ||||||||
| 2020-03-18 | 3 | Fuhrman Alan | ESPR | Common Stock | D | 1,308 | ||||||||
| 2020-03-12 | 2020-03-11 | 4 | MAYLEBEN TIMOTHY M | ESPR | Common Stock | D | 43.0000 | 2,500 | 108 | 111,998 | ||||
| 2020-03-02 | 2020-02-28 | 4 | MAYLEBEN TIMOTHY M | ESPR | Common Stock | D | 49.0000 | 5,000 | 245 | 109,498 | ||||
| 2020-02-28 | 3 | Hall Ashley | ESPR | Common Stock | D | 21,000 | ||||||||
| 2020-02-28 | 3 | Hall Ashley | ESPR | Common Stock | D | 25,500 | ||||||||
| 2020-02-28 | 3 | Hall Ashley | ESPR | Common Stock | D | 21,000 | ||||||||
| 2020-02-28 | 3 | Hall Ashley | ESPR | Common Stock | D | 25,500 | ||||||||
| 2020-02-28 | 3 | Hall Ashley | ESPR | Common Stock | D | 25,500 | ||||||||
| 2020-02-28 | 3 | Hall Ashley | ESPR | Common Stock | D | 21,000 | ||||||||
| 2020-01-27 | 2020-01-23 | 4 | BIOTECH TARGET N V | ESPR | Common Stock | D | 52.1199 | 20,000 | 1,042 | 3,747,964 | ||||
| 2020-01-03 | 2020-01-02 | 4 | MAYLEBEN TIMOTHY M | ESPR | Stock Option (right to buy) | D | 61.34 | 104,175 | 104,175 | |||||
| 2020-01-03 | 2020-01-02 | 4 | MAYLEBEN TIMOTHY M | ESPR | Common Stock | D | 23,150 | 104,498 | ||||||
| 2020-01-03 | 2019-11-15 | 4 | MAYLEBEN TIMOTHY M | ESPR | Common Stock | D | -365 | 81,348 | ||||||
| 2020-01-03 | 2019-11-11 | 4 | MAYLEBEN TIMOTHY M | ESPR | Common Stock | D | -1,950 | 81,173 | ||||||
| 2020-01-03 | 2020-01-02 | 4 | Bartram Richard | ESPR | Stock Option (right to buy) | D | 61.34 | 33,900 | 33,900 | |||||
| 2020-01-03 | 2020-01-02 | 4 | Bartram Richard | ESPR | Common Stock | D | 7,525 | 18,673 | ||||||
| 2020-01-03 | 2020-01-02 | 4 | Glickman Mark A | ESPR | Stock Option (right to buy | D | 61.34 | 26,625 | 26,625 | |||||
| 2020-01-03 | 2020-01-02 | 4 | Glickman Mark A | ESPR | Common Stock | D | 5,925 | 25,925 | ||||||
| 2019-11-08 | 2019-11-06 | 4 | MAYLEBEN TIMOTHY M | ESPR | Common Stock | D | 36.9800 | 5,000 | 185 | 83,663 | ||||
| 2019-11-08 | 2019-11-06 | 4 | BIOTECH TARGET N V | ESPR | Common Stock | D | 37.3008 | 75,000 | 2,798 | 3,727,964 | ||||
| 2019-09-06 | 2019-09-04 | 4 | BIOTECH TARGET N V | ESPR | Common Stock | D | 33.7776 | 80,000 | 2,702 | 3,652,964 | ||||
| 2019-09-06 | 2019-09-06 | 4 | MAYLEBEN TIMOTHY M | ESPR | Common Stock | D | 35.2500 | 2,500 | 88 | 78,663 | ||||
| 2019-09-06 | 2019-09-04 | 4 | MAYLEBEN TIMOTHY M | ESPR | Common Stock | D | 33.4200 | 148 | 5 | 76,163 | ||||
| 2019-09-06 | 2019-09-04 | 4 | MAYLEBEN TIMOTHY M | ESPR | Common Stock | D | 34.2200 | 4,852 | 166 | 76,015 | ||||
| 2019-08-02 | 2019-08-01 | 4 | MAYLEBEN TIMOTHY M | ESPR | Common Stock | D | 39.5600 | 5,000 | 198 | 71,163 | ||||
| 2019-07-25 | 2019-07-23 | 4 | BIOTECH TARGET N V | ESPR | Common Stock | D | 42.6513 | 50,000 | 2,133 | 3,572,964 | ||||
| 2019-07-01 | 2019-06-28 | 4 | MAYLEBEN TIMOTHY M | ESPR | Common Stock | D | 46.0000 | 5,000 | 230 | 66,163 | ||||
| 2019-05-31 | 2019-05-29 | 4 | VITULLO NICOLE | ESPR | Common Stock | D | 4,967 | 13,286 | ||||||
| 2019-05-31 | 2019-05-29 | 4 | Shepard Jay | ESPR | Common Stock | D | 4,967 | 4,967 | ||||||
| 2019-05-31 | 2019-05-29 | 4 | MCGOVERN MARK E | ESPR | Common Stock | D | 4,967 | 9,967 | ||||||
| 2019-05-31 | 2019-05-29 | 4 | GOTTO ANTONIO M JR MD D PHIL | ESPR | Common Stock | D | 4,967 | 4,967 | ||||||
| 2019-05-31 | 2019-05-29 | 4 | JANNEY DANIEL | ESPR | Common Stock | D | 4,967 | 4,967 | ||||||
| 2019-05-31 | 2018-02-28 | 4 | JANNEY DANIEL By Alta Bioequities, L.P. | ESPR | Common Stock | I | 24,565 | 24,565 | ||||||
| 2019-05-31 | 2019-05-29 | 4 | Berkowitz Jeffrey | ESPR | Common Stock | D | 4,967 | 4,967 | ||||||
| 2019-05-31 | 2019-05-29 | 4 | Braunstein Scott | ESPR | Common Stock | D | 4,967 | 5,019 | ||||||
| 2019-05-31 | 2019-05-29 | 4 | Woody Tracy M | ESPR | Common Stock | D | 9,934 | 9,934 | ||||||
| 2019-04-05 | 2019-04-03 | 4 | Bartram Richard | ESPR | Common Stock | D | 43.6200 | 1,500 | 65 | 11,092 | ||||
| 2019-04-05 | 2019-04-03 | 4 | Bartram Richard | ESPR | Common Stock | D | 42.7100 | 6,500 | 278 | 12,592 | ||||
| 2019-04-01 | 2019-03-29 | 4 | MAYLEBEN TIMOTHY M | ESPR | Common Stock | D | 40.0000 | 5,000 | 200 | 61,163 | ||||
| 2019-03-21 | 2019-03-20 | 4 | MAYLEBEN TIMOTHY M | ESPR | Common Stock | D | 43.4800 | 5,000 | 217 | 56,163 | ||||
| 2019-03-21 | 2019-03-21 | 4 | VITULLO NICOLE | ESPR | Common Stock | D | 1,356 | 8,319 | ||||||
| 2019-03-21 | 2019-03-21 | 4 | VITULLO NICOLE By One Palmer Square Associates VII, LLC | ESPR | Common Stock | I | -17,790 | 0 | ||||||
| 2019-03-21 | 2019-03-19 | 4 | VITULLO NICOLE By DP VII Associates, L.P. | ESPR | Common Stock | I | 45.2500 | -1,700 | -77 | 0 | ||||
| 2019-03-21 | 2019-03-19 | 4 | VITULLO NICOLE By DP VII Associates, L.P. | ESPR | Common Stock | I | 44.6600 | -13,629 | -609 | 1,700 | ||||
| 2019-03-21 | 2019-03-19 | 4 | VITULLO NICOLE By One Palmer Square Associates VII, LLC | ESPR | Common Stock | I | 17,790 | 17,790 | ||||||
| 2019-03-21 | 2019-03-19 | 4 | VITULLO NICOLE By Domain Partners VII, L.P. | ESPR | Common Stock | I | -1,101,080 | 0 | ||||||
| 2019-03-15 | 2019-03-14 | 4 | BIOTECH TARGET N V | ESPR | Common Stock | D | 49.8871 | 50,000 | 2,494 | 3,522,964 | ||||
| 2019-03-14 | 2019-03-12 | 4 | NEWTON ROGER S | ESPR | Common Stock | D | 50.0600 | -25,000 | -1,252 | 548,726 | ||||
| 2019-03-14 | 2019-03-14 | 4 | MAYLEBEN TIMOTHY M | ESPR | Common Stock | D | 48.7300 | 5,000 | 244 | 51,163 | ||||
| 2019-01-07 | 2019-01-04 | 4 | BIOTECH TARGET N V | ESPR | Common Stock | D | 41.2907 | 80,000 | 3,303 | 3,472,964 | ||||
| 2018-12-26 | 2018-12-24 | 4 | BIOTECH TARGET N V | ESPR | Common Stock | D | 39.9145 | 50,000 | 1,996 | 3,392,964 | ||||
| 2018-12-21 | 3 | Glickman Mark A | ESPR | Common Stock | D | 40,000 | ||||||||
| 2018-12-21 | 3 | Glickman Mark A | ESPR | Common Stock | D | 40,000 | ||||||||
| 2018-12-21 | 3 | Glickman Mark A | ESPR | Common Stock | D | 40,000 | ||||||||
| 2018-12-19 | 2018-12-17 | 4 | BIOTECH TARGET N V | ESPR | Common Stock | D | 47.7345 | 60,000 | 2,864 | 3,342,964 | ||||
| 2018-11-30 | 2018-11-28 | 4 | MAYLEBEN TIMOTHY M | ESPR | Stock Option (right to buy) | D | 52.38 | 110,000 | 110,000 | |||||
| 2018-11-30 | 2018-11-28 | 4 | Lalwani Narendra D. | ESPR | Stock Option (right to buy) | D | 52.38 | 8,000 | 8,000 | |||||
| 2018-11-30 | 2018-11-28 | 4 | Bartram Richard | ESPR | Stock Option (right to buy) | D | 52.38 | 12,000 | 12,000 | |||||
| 2018-11-05 | 2018-11-05 | 4 | Boxer Capital, LLC | ESPR | Common Stock | D | 60.2800 | -5,000 | -301 | 1,101,250 | ||||
| 2018-11-05 | 2018-11-05 | 4 | Boxer Capital, LLC | ESPR | Common Stock | D | 59.4800 | -13,610 | -810 | 1,106,250 | ||||
| 2018-11-05 | 2018-11-05 | 4 | Boxer Capital, LLC | ESPR | Common Stock | D | 58.8200 | -6,390 | -376 | 1,119,860 | ||||
| 2018-11-05 | 2018-11-05 | 4 | Boxer Capital, LLC | ESPR | Common Stock | D | 57.3800 | -2,000 | -115 | 1,126,250 | ||||
| 2018-11-05 | 2018-11-05 | 4 | Boxer Capital, LLC | ESPR | Common Stock | D | 56.1900 | -6,500 | -365 | 1,128,250 | ||||
| 2018-11-05 | 2018-11-05 | 4 | Boxer Capital, LLC | ESPR | Common Stock | D | 55.2100 | -26,500 | -1,463 | 1,134,750 | ||||
| 2018-11-05 | 2018-11-02 | 4 | Boxer Capital, LLC | ESPR | Common Stock | D | 55.2500 | -37,500 | -2,072 | 1,161,250 | ||||
| 2018-11-05 | 2018-11-02 | 4 | Boxer Capital, LLC | ESPR | Common Stock | D | 54.6500 | -2,500 | -137 | 1,198,750 | ||||
| 2018-11-02 | 2018-11-02 | 4 | NEWTON ROGER S | ESPR | Common Stock | D | 50.7600 | -227 | -12 | 573,726 | ||||
| 2018-11-02 | 2018-11-01 | 4 | NEWTON ROGER S | ESPR | Common Stock | D | 50.0100 | -2,600 | -130 | 573,953 | ||||
| 2018-10-30 | 3 | Boxer Capital, LLC | ESPR | Common Stock | D | 2,602,450 | ||||||||
| 2018-10-30 | 3 | Boxer Capital, LLC | ESPR | Common Stock | D | 4,003,350 | ||||||||
| 2018-10-30 | 3 | Boxer Capital, LLC | ESPR | Common Stock | D | 3,803,600 | ||||||||
| 2018-10-30 | 3 | Boxer Capital, LLC | ESPR | Common Stock | D | 4,003,350 | ||||||||
| 2018-10-30 | 3 | Boxer Capital, LLC | ESPR | Common Stock | D | 3,803,600 | ||||||||
| 2018-10-30 | 3 | Boxer Capital, LLC | ESPR | Common Stock | D | 2,602,450 | ||||||||
| 2018-10-30 | 3 | Boxer Capital, LLC | ESPR | Common Stock | D | 4,003,350 | ||||||||
| 2018-10-30 | 3 | Boxer Capital, LLC | ESPR | Common Stock | D | 3,803,600 | ||||||||
| 2018-10-30 | 3 | Boxer Capital, LLC | ESPR | Common Stock | D | 2,602,450 | ||||||||
| 2018-10-30 | 3 | Boxer Capital, LLC | ESPR | Common Stock | D | 3,803,600 | ||||||||
| 2018-10-30 | 3 | Boxer Capital, LLC | ESPR | Common Stock | D | 2,602,450 | ||||||||
| 2018-10-30 | 3 | Boxer Capital, LLC | ESPR | Common Stock | D | 4,003,350 | ||||||||
| 2018-10-30 | 3 | Boxer Capital, LLC | ESPR | Common Stock | D | 3,803,600 | ||||||||
| 2018-10-30 | 3 | Boxer Capital, LLC | ESPR | Common Stock | D | 2,602,450 | ||||||||
| 2018-10-30 | 3 | Boxer Capital, LLC | ESPR | Common Stock | D | 4,003,350 | ||||||||
| 2018-10-30 | 3 | Boxer Capital, LLC | ESPR | Common Stock | D | 3,803,600 | ||||||||
| 2018-10-30 | 3 | Boxer Capital, LLC | ESPR | Common Stock | D | 2,602,450 | ||||||||
| 2018-10-30 | 3 | Boxer Capital, LLC | ESPR | Common Stock | D | 4,003,350 | ||||||||
| 2018-10-30 | 3 | Boxer Capital, LLC | ESPR | Common Stock | D | 4,003,350 | ||||||||
| 2018-10-30 | 3 | Boxer Capital, LLC | ESPR | Common Stock | D | 3,803,600 | ||||||||
| 2018-10-30 | 3 | Boxer Capital, LLC | ESPR | Common Stock | D | 2,602,450 | ||||||||
| 2018-10-18 | 2018-10-18 | 4 | NEWTON ROGER S | ESPR | Common Stock | D | 50.0000 | -100 | -5 | 576,553 | ||||
| 2018-10-18 | 2018-10-17 | 4 | NEWTON ROGER S | ESPR | Common Stock | D | 50.0200 | -12,673 | -634 | 576,653 | ||||
| 2018-10-18 | 2018-10-16 | 4 | NEWTON ROGER S | ESPR | Common Stock | D | 50.0100 | -9,400 | -470 | 589,326 | ||||
| 2018-08-29 | 2018-08-27 | 4 | NEWTON ROGER S | ESPR | Common Stock | D | 50.6500 | -12,100 | -613 | 598,726 | ||||
| 2018-08-29 | 2018-08-27 | 4 | NEWTON ROGER S | ESPR | Common Stock | D | 51.4600 | -4,200 | -216 | 610,826 | ||||
| 2018-08-29 | 2018-08-27 | 4 | NEWTON ROGER S | ESPR | Common Stock | D | 52.9100 | -700 | -37 | 615,026 | ||||
| 2018-08-29 | 2018-08-27 | 4 | NEWTON ROGER S | ESPR | Common Stock | D | 53.6800 | -700 | -38 | 615,726 | ||||
| 2018-08-22 | 2018-08-17 | 4 | NEWTON ROGER S | ESPR | Common Stock | D | 50.0600 | -7,300 | -365 | 616,426 | ||||
| 2018-08-06 | 2018-08-03 | 4 | BIOTECH TARGET N V | ESPR | Common Stock | D | 46.1394 | 50,000 | 2,307 | 3,282,964 | ||||
| 2018-07-13 | 2018-07-12 | 4 | BIOTECH TARGET N V | ESPR | Common Stock | D | 41.7660 | 50,000 | 2,088 | 3,232,964 | ||||
| 2018-07-03 | 2018-06-29 | 4 | BIOTECH TARGET N V | ESPR | Common Stock | D | 39.4761 | 50,000 | 1,974 | 3,182,964 | ||||
| 2018-06-26 | 2018-06-22 | 4 | VITULLO NICOLE | ESPR | Common Stock | D | 3,846 | 6,963 | ||||||
| 2018-06-26 | 2018-06-22 | 4 | VITULLO NICOLE By Domain Associates, LLC | ESPR | Common Stock | I | -21,471 | 0 | ||||||
| 2018-06-25 | 2018-06-21 | 4 | BIOTECH TARGET N V | ESPR | Common Stock | D | 38.5704 | 60,000 | 2,314 | 3,132,964 | ||||
| 2018-06-11 | 2018-06-07 | 4 | BIOTECH TARGET N V | ESPR | Common Stock | D | 37.7882 | 60,000 | 2,267 | 3,072,964 | ||||
| 2018-06-08 | 2018-06-06 | 4 | GOLDSTEIN DOV A MD | ESPR | Stock Option (right to buy) | D | 17.75 | 8,000 | 0 | |||||
| 2018-06-08 | 2018-06-06 | 4 | GOLDSTEIN DOV A MD | ESPR | Stock Option (right to buy) | D | 14.42 | 5,000 | 0 | |||||
| 2018-06-08 | 2018-06-06 | 4 | GOLDSTEIN DOV A MD | ESPR | Common Stock | D | -8,000 | 47 | ||||||
| 2018-06-08 | 2018-06-06 | 4 | GOLDSTEIN DOV A MD | ESPR | Common Stock | D | -5,000 | 8,047 | ||||||
| 2018-06-08 | 2018-06-06 | 4 | GOLDSTEIN DOV A MD | ESPR | Common Stock | D | 17.7500 | 8,000 | 142 | 13,047 | ||||
| 2018-06-08 | 2018-06-06 | 4 | GOLDSTEIN DOV A MD | ESPR | Common Stock | D | 14.4200 | 5,000 | 72 | 5,047 | ||||
| 2018-06-07 | 2018-06-05 | 4 | BIOTECH TARGET N V | ESPR | Common Stock | D | 38.4740 | 60,000 | 2,308 | 3,012,964 | ||||
| 2018-05-29 | 2018-05-24 | 4 | Shepard Jay | ESPR | Stock Option (right to buy) | D | 37.69 | 18,700 | 18,700 | |||||
| 2018-05-25 | 2018-05-23 | 4 | Braunstein Scott | ESPR | Stock Option (right to buy) | D | 38.32 | 10,100 | 10,100 | |||||
| 2018-05-25 | 2018-05-23 | 4 | Berkowitz Jeffrey | ESPR | Stock Option (right to buy) | D | 38.32 | 4,427 | 4,427 | |||||
| 2018-05-25 | 2018-05-23 | 4 | MCGOVERN MARK E | ESPR | Stock Option (right to buy) | D | 38.32 | 10,100 | 10,100 | |||||
| 2018-05-25 | 2018-05-23 | 4 | NEWTON ROGER S | ESPR | Stock Option (right tobuy) | D | 38.32 | 10,100 | 10,100 | |||||
| 2018-05-25 | 2018-05-23 | 4 | JANNEY DANIEL | ESPR | Stock Option (right to buy) | D | 38.32 | 10,100 | 10,100 | |||||
| 2018-05-25 | 2018-05-23 | 4 | VITULLO NICOLE | ESPR | Stock Option (Right to Buy) | D | 38.32 | 10,100 | 10,100 | |||||
| 2018-05-25 | 2018-05-23 | 4 | GOTTO ANTONIO M JR MD D PHIL | ESPR | Stock Option (right to buy) | D | 38.32 | 10,100 | 10,100 | |||||
| 2018-05-25 | 2018-05-23 | 4 | GOLDSTEIN DOV A MD | ESPR | Stock Option (right to buy) | D | 38.32 | 10,100 | 10,100 | |||||
| 2018-05-22 | 2018-05-21 | 4 | BIOTECH TARGET N V | ESPR | Common Stock | D | 38.7720 | 80,000 | 3,102 | 2,952,964 | ||||
| 2018-05-22 | 2018-05-18 | 4 | BIOTECH TARGET N V | ESPR | Common Stock | D | 42.2402 | 50,000 | 2,112 | 2,872,964 | ||||
| 2018-05-10 | 3 | BB BIOTECH AG | ESPR | Common Stock | D | 5,645,928 | ||||||||
| 2018-05-10 | 3 | BB BIOTECH AG | ESPR | Common Stock | D | 5,645,928 | ||||||||
| 2018-05-10 | 3 | BB BIOTECH AG | ESPR | Common Stock | D | 5,645,928 | ||||||||
| 2018-05-10 | 3 | BB BIOTECH AG | ESPR | Common Stock | D | 5,645,928 | ||||||||
| 2018-03-29 | 2018-03-29 | 4 | NEWTON ROGER S | ESPR | Common Stock | D | 70.7100 | 200 | 14 | 623,726 | ||||
| 2018-03-29 | 2018-03-29 | 4 | NEWTON ROGER S | ESPR | Common Stock | D | 71.3600 | 7,100 | 507 | 623,926 | ||||
| 2018-03-29 | 2018-03-29 | 4 | NEWTON ROGER S | ESPR | Common Stock | D | 72.3100 | 8,656 | 626 | 631,026 | ||||
| 2018-03-29 | 2018-03-29 | 4 | NEWTON ROGER S | ESPR | Common Stock | D | 73.2600 | -9,044 | -663 | 639,682 | ||||
| 2018-02-23 | 2018-02-22 | 4 | Berkowitz Jeffrey | ESPR | Stock option (right to buy) | D | 77.94 | 25,000 | 25,000 | |||||
| 2018-02-09 | 2018-02-07 | 4 | NEWTON ROGER S | ESPR | Warrant to Purchase Common Stock | D | 6.99 | -34,651 | 0 | |||||
| 2018-02-09 | 2018-02-07 | 4 | NEWTON ROGER S | ESPR | Common Stock | D | 6.9900 | -3,608 | -25 | 648,726 | ||||
| 2018-02-09 | 2018-02-07 | 4 | NEWTON ROGER S | ESPR | Common Stock | D | 6.9900 | 34,651 | 242 | 652,334 | ||||
| 2018-02-09 | 2017-12-12 | 4 | NEWTON ROGER S | ESPR | Common Stock | D | -12,000 | 617,683 | ||||||
| 2018-02-01 | 2018-01-31 | 4 | MAYLEBEN TIMOTHY M | ESPR | Stock Option (right to buy) | D | 1.26 | -2,610 | 0 | |||||
| 2018-02-01 | 2018-01-31 | 4 | MAYLEBEN TIMOTHY M | ESPR | Stock Option (right to buy) | D | 1.05 | -1,939 | 0 | |||||
| 2018-02-01 | 2018-01-31 | 4 | MAYLEBEN TIMOTHY M | ESPR | Common Stock | D | 1.2600 | 2,610 | 3 | 46,163 | ||||
| 2018-02-01 | 2018-01-31 | 4 | MAYLEBEN TIMOTHY M | ESPR | Common Stock | D | 1.0500 | 1,939 | 2 | 43,553 | ||||
| 2018-01-26 | 2018-01-26 | 4 | VITULLO NICOLE | ESPR | Common Stock | D | 645 | 3,177 | ||||||
| 2018-01-26 | 2018-01-26 | 4 | VITULLO NICOLE By One Palmer Square Associates VII, LLC | ESPR | Common Stock | I | -8,500 | 0 | ||||||
| 2018-01-26 | 2018-01-25 | 4 | VITULLO NICOLE By DP VII Associates, L.P. | ESPR | Common Stock | I | 71.7900 | -11,674 | -838 | 15,329 | ||||
| 2018-01-26 | 2018-01-24 | 4 | VITULLO NICOLE By DP VII Associates, L.P. | ESPR | Warrant to Purchase Common Stock | I | 6.99 | -1,193 | 0 | |||||
| 2018-01-26 | 2018-01-24 | 4 | VITULLO NICOLE By Domain Partners VII, L.P. | ESPR | Warrant to Purchase Common Stock | I | 6.99 | -70,042 | 0 | |||||
| 2018-01-26 | 2018-01-24 | 4 | VITULLO NICOLE By DP VII Associates, L.P. | ESPR | Common Stock | I | 71.8200 | -117 | -8 | 27,003 | ||||
| 2018-01-26 | 2018-01-24 | 4 | VITULLO NICOLE By DP VII Associates, L.P. | ESPR | Common Stock | I | 6.9900 | 1,193 | 8 | 27,120 | ||||
| 2018-01-26 | 2018-01-24 | 4 | VITULLO NICOLE By Domain Partners VII, L.P. | ESPR | Common Stock | I | 71.8200 | -6,814 | -489 | 1,101,080 | ||||
| 2018-01-26 | 2018-01-24 | 4 | VITULLO NICOLE By Domain Partners VII, L.P. | ESPR | Common Stock | I | 6.9900 | 70,042 | 490 | 1,107,894 | ||||
| 2018-01-26 | 2018-01-24 | 4 | VITULLO NICOLE By One Palmer Square Associates VII, LLC | ESPR | Common Stock | I | 8,500 | 8,500 | ||||||
| 2018-01-26 | 2018-01-24 | 4 | VITULLO NICOLE By Domain Partners VII, L.P. | ESPR | Common Stock | I | -850,000 | 1,037,852 | ||||||
| 2018-01-22 | 2018-01-18 | 4 | JANNEY DANIEL | ESPR | Warrant to Purchase Common Stock | I | 6.99 | -71,237 | 0 | |||||
| 2018-01-22 | 2018-01-18 | 4 | JANNEY DANIEL | ESPR | Common Stock | I | 74.9600 | -6,640 | -498 | 624,564 | ||||
| 2018-01-22 | 2018-01-18 | 4 | JANNEY DANIEL | ESPR | Common Stock | I | 6.9900 | 71,237 | 498 | 631,204 | ||||
| 2018-01-22 | 2017-12-29 | 4 | JANNEY DANIEL | ESPR | Common Stock | I | -7,020 | 0 | ||||||
| 2018-01-22 | 2017-12-29 | 4 | JANNEY DANIEL | ESPR | Common Stock | I | -31,466 | 0 | ||||||
| 2018-01-03 | 2018-01-02 | 4 | MAYLEBEN TIMOTHY M | ESPR | Stock Option (right to buy) | D | 66.50 | 107,000 | 107,000 | |||||
| 2018-01-03 | 2018-01-02 | 4 | Lalwani Narendra D. | ESPR | Stock Option (right to buy) | D | 66.50 | 36,000 | 36,000 | |||||
| 2018-01-03 | 2018-01-02 | 4 | Bartram Richard | ESPR | Stock Option (right to buy) | D | 3.70 | 17,892 | 0 | |||||
| 2018-01-03 | 2018-01-02 | 4 | Bartram Richard | ESPR | Stock Option (right to buy) | D | 66.50 | 38,500 | 38,500 | |||||
| 2018-01-03 | 2018-01-02 | 4 | Bartram Richard | ESPR | Common Stock | D | 3.7000 | 17,892 | 66 | 19,092 | ||||
| 2017-12-20 | 2017-12-18 | 4 | GOLDSTEIN DOV A MD | ESPR | Stock Option (right to buy) | D | 3.70 | -21,471 | 0 | |||||
| 2017-12-20 | 2017-12-18 | 4 | GOLDSTEIN DOV A MD | ESPR | Common Stock | D | -21,471 | 47 | ||||||
| 2017-12-20 | 2017-12-18 | 4 | GOLDSTEIN DOV A MD | ESPR | Common Stock | D | 3.7000 | 21,471 | 79 | 21,518 | ||||
| 2017-12-14 | 3 | Bartram Richard | ESPR | Common Stock | D | 2,400 | ||||||||
| 2017-12-14 | 3 | Bartram Richard | ESPR | Common Stock | D | 2,400 | ||||||||
| 2017-12-08 | 2017-12-05 | 4 | GOLDSTEIN DOV A MD | ESPR | Common Stock | D | 38 | 47 | ||||||
| 2017-12-08 | 2017-12-08 | 4 | VITULLO NICOLE | ESPR | Common Stock | D | 2,472 | 2,472 | ||||||
| 2017-12-08 | 2017-12-08 | 4 | VITULLO NICOLE By One Palmer Square Associates VII, LLC | ESPR | Common Stock | I | -32,560 | 0 | ||||||
| 2017-12-08 | 2017-12-06 | 4 | VITULLO NICOLE By DP VII Associates, L.P. | ESPR | Common Stock | I | 53.8500 | -9,326 | -502 | 25,927 | ||||
| 2017-12-08 | 2017-12-06 | 4 | VITULLO NICOLE By One Palmer Square Associates VII, LLC | ESPR | Common Stock | I | 3,291 | 32,560 | ||||||
| 2017-12-08 | 2017-12-06 | 4 | VITULLO NICOLE By Domain Partners VII, L.P. | ESPR | Common Stock | I | -329,083 | 1,887,852 | ||||||
| 2017-04-19 | 2017-04-17 | 4 | GOLDSTEIN DOV A MD | ESPR | Stock Option (right to buy) | D | 38.96 | 14,000 | 14,000 | |||||
| 2017-04-19 | 2017-04-17 | 4 | VITULLO NICOLE | ESPR | Stock Option (Right to Buy) | D | 38.96 | 14,000 | 14,000 | |||||
| 2017-04-19 | 2017-04-17 | 4 | OMENN GILBERT S | ESPR | Stock Option (right to buy) | D | 38.96 | 14,000 | 14,000 | |||||
| 2017-04-19 | 2017-04-17 | 4 | MCGOVERN MARK E | ESPR | Stock Option (right to buy) | D | 38.96 | 14,000 | 14,000 | |||||
| 2017-04-19 | 2017-04-17 | 4 | Braunstein Scott | ESPR | Stock Option (right to buy) | D | 38.96 | 14,000 | 14,000 | |||||
| 2017-04-19 | 2017-04-17 | 4 | GOTTO ANTONIO M JR MD D PHIL | ESPR | Stock Option (right to buy) | D | 38.96 | 14,000 | 14,000 | |||||
| 2017-04-19 | 2017-04-17 | 4 | NEWTON ROGER S | ESPR | Stock Option (right to buy) | D | 38.96 | 14,000 | 14,000 | |||||
| 2017-04-19 | 2017-04-17 | 4 | JANNEY DANIEL | ESPR | Stock Option (right to buy) | D | 38.96 | 14,000 | 14,000 | |||||
| 2017-03-23 | 2017-03-21 | 4 | JANNEY DANIEL | ESPR | Common Stock | I | 48.1900 | -700 | -34 | 1,359,967 | ||||
| 2017-03-23 | 2017-03-21 | 4 | JANNEY DANIEL | ESPR | Common Stock | I | 47.5400 | -56,855 | -2,703 | 1,360,667 | ||||
| 2017-03-23 | 2017-03-21 | 4 | JANNEY DANIEL | ESPR | Common Stock | I | 46.6000 | -59,798 | -2,787 | 1,417,522 | ||||
| 2017-03-23 | 2017-03-21 | 4 | JANNEY DANIEL | ESPR | Common Stock | I | 45.4300 | -111,307 | -5,057 | 1,477,320 | ||||
| 2017-03-23 | 2017-03-21 | 4 | JANNEY DANIEL | ESPR | Common Stock | I | 44.9100 | -121,340 | -5,449 | 1,588,627 | ||||
| 2017-03-23 | 2017-03-22 | 4 | GOLDSTEIN DOV A MD By Aisling Capital II, LP | ESPR | Common Stock | I | 38.8200 | -312,642 | -12,137 | 837,125 | ||||
| 2017-03-23 | 2017-03-21 | 4 | GOLDSTEIN DOV A MD By Aisling Capital II, LP | ESPR | Common Stock | I | 43.4800 | -487,358 | -21,190 | 1,149,767 | ||||
| 2017-03-22 | 2017-03-21 | 4 | OMENN GILBERT S By Gilbert S. Omenn Revocable Trust | ESPR | Common Stock | I | 42.2600 | 1,000 | 42 | 1,000 | ||||
| 2017-02-22 | 2017-02-21 | 4 | MAYLEBEN TIMOTHY M | ESPR | Stock Option (right to buy) | D | 24.42 | 171,100 | 171,100 | |||||
| 2017-02-22 | 2017-02-21 | 4 | McGowan Mary | ESPR | Stock Option (right to buy) | D | 24.42 | 140,000 | 140,000 | |||||
| 2017-02-22 | 2017-02-21 | 4 | Lalwani Narendra D. | ESPR | Stock Option (right to buy) | D | 24.42 | 10,800 | 10,800 | |||||
| 2017-01-03 | 2017-01-03 | 4 | MAYLEBEN TIMOTHY M | ESPR | Stock option (right to buy) | D | 12.88 | 140,000 | 140,000 | |||||
| 2017-01-03 | 2017-01-03 | 4 | Lalwani Narendra D. | ESPR | Stock Option (right to buy) | D | 12.88 | 55,000 | 55,000 | |||||
| 2017-01-03 | 2017-01-03 | 4 | McGowan Mary | ESPR | Stock Option (right to buy) | D | 12.88 | 50,000 | 50,000 | |||||
| 2016-11-03 | 2016-11-01 | 4 | Lalwani Narendra D. | ESPR | Common Stock | D | 9.9300 | 5,000 | 50 | 5,000 | ||||
| 2016-07-07 | 2016-07-06 | 4 | MCGOVERN MARK E | ESPR | Common Stock | D | 10.0000 | 4,400 | 44 | 5,000 | ||||
| 2016-07-07 | 2016-07-05 | 4 | MCGOVERN MARK E | ESPR | Common Stock | D | 10.0000 | 600 | 6 | 600 | ||||
| 2016-06-13 | 2016-06-09 | 4 | VITULLO NICOLE | ESPR | Stock Option (Right to Buy) | D | 17.75 | 8,000 | 8,000 | |||||
| 2016-06-10 | 2016-06-09 | 4 | GOLDSTEIN DOV A MD | ESPR | Stock Option (right to buy) | D | 17.75 | 8,000 | 8,000 | |||||
| 2016-06-10 | 2016-06-09 | 4 | OMENN GILBERT S | ESPR | Stock Option (right to buy) | D | 17.75 | 8,000 | 8,000 | |||||
| 2016-06-10 | 2016-06-09 | 4 | MCGOVERN MARK E | ESPR | Stock Option (right to buy) | D | 17.75 | 8,000 | 8,000 | |||||
| 2016-06-10 | 2016-06-09 | 4 | JANNEY DANIEL | ESPR | Stock Option (right to buy) | D | 17.75 | 8,000 | 8,000 | |||||
| 2016-06-10 | 2016-06-09 | 4 | GOTTO ANTONIO M JR MD D PHIL | ESPR | Stock Option (right to buy) | D | 17.75 | 8,000 | 8,000 | |||||
| 2016-06-10 | 2016-06-09 | 4 | Braunstein Scott | ESPR | Stock Option (right to buy) | D | 17.75 | 8,000 | 8,000 | |||||
| 2016-05-05 | 2016-05-04 | 4 | MAYLEBEN TIMOTHY M | ESPR | Common Stock | D | 14.8500 | 7,000 | 104 | 41,614 | ||||
| 2016-03-02 | 2016-03-01 | 4 | OMENN GILBERT S | ESPR | Common Stock | D | 15.2800 | 5,000 | 76 | 10,000 | ||||
| 2016-01-28 | 2016-01-27 | 4 | MAYLEBEN TIMOTHY M | ESPR | Common Stock | D | 15.8800 | 3,600 | 57 | 34,614 | ||||
| 2016-01-19 | 2016-01-15 | 4 | MAYLEBEN TIMOTHY M | ESPR | Common Stock | D | 14.0800 | 7,200 | 101 | 31,014 | ||||
| 2016-01-05 | 2016-01-04 | 4 | McGowan Mary | ESPR | Stock Option (right to buy) | D | 21.65 | 15,000 | 15,000 | |||||
| 2016-01-05 | 2016-01-04 | 4 | Lalwani Narendra D. | ESPR | Stock Option (right to buy) | D | 21.65 | 15,000 | 15,000 | |||||
| 2016-01-05 | 2016-01-04 | 4 | MAYLEBEN TIMOTHY M | ESPR | Stock Option (right to buy) | D | 21.65 | 30,000 | 22 | |||||
| 2015-12-18 | 3 | Shah Nimesh By Domain Associates, LLC | ESPR | Common Stock | I | 42,942 | ||||||||
| 2015-12-18 | 3 | Shah Nimesh By Domain Associates, LLC | ESPR | Common Stock | I | 42,942 | ||||||||
| 2015-08-21 | 2015-08-19 | 4 | McGowan Mary | ESPR | Stock Option (right to buy) | D | 57.54 | 210,000 | 210,000 | |||||
| 2015-08-21 | 2015-08-19 | 4 | McGowan Mary | ESPR | Common Stock | D | 15,000 | 15,000 | ||||||
| 2015-08-21 | 2015-08-19 | 4 | Braunstein Scott | ESPR | Stock Option (right to buy) | D | 57.54 | 20,000 | 20,000 | |||||
| 2015-06-15 | 3 | Braunstein Scott | ESPR | Common Stock | D | 104 | ||||||||
| 2015-06-15 | 3 | Braunstein Scott | ESPR | Common Stock | D | 104 | ||||||||
| 2015-05-18 | 2015-05-14 | 4 | GOLDSTEIN DOV A MD | ESPR | Stock Option (right to buy) | D | 107.74 | 8,000 | 8,000 | |||||
| 2015-05-18 | 2015-05-14 | 4 | OMENN GILBERT S | ESPR | Stock Option (right to buy) | D | 107.74 | 8,000 | 8,000 | |||||
| 2015-05-18 | 2015-05-14 | 4 | MCGOVERN MARK E | ESPR | Stock Option (right to buy) | D | 107.74 | 8,000 | 8,000 | |||||
| 2015-05-18 | 2015-05-14 | 4 | ENRIGHT PATRICK G | ESPR | Stock Option (right to buy) | D | 107.74 | 8,000 | 8,000 | |||||
| 2015-05-18 | 2015-05-14 | 4 | JANNEY DANIEL | ESPR | Stock Option (right to buy) | D | 107.74 | 8,000 | 8,000 | |||||
| 2015-05-18 | 2015-05-14 | 4 | GOTTO ANTONIO M JR MD D PHIL | ESPR | Stock Option (right to buy) | D | 107.74 | 8,000 | 8,000 | |||||
| 2015-05-15 | 2015-05-14 | 4 | VITULLO NICOLE | ESPR | Stock Option (Right to Buy) | D | 107.74 | 8,000 | 8,000 | |||||
| 2015-04-30 | 2015-04-28 | 4 | GOLDSTEIN DOV A MD By Aisling Capital II, LP | ESPR | Common Stock | I | -199,991 | 1,637,125 | ||||||
| 2015-04-27 | 2015-04-24 | 4 | GOLDSTEIN DOV A MD By Aisling Capital II, LP | ESPR | Common Stock | I | 106.1000 | -61,726 | -6,549 | 1,837,125 | ||||
| 2015-04-27 | 2015-04-24 | 4 | GOLDSTEIN DOV A MD By Aisling Capital II, LP | ESPR | Common Stock | I | 108.0000 | -5,743 | -620 | 1,898,851 | ||||
| 2015-04-27 | 2015-04-23 | 4 | GOLDSTEIN DOV A MD By Aisling Capital II, LP | ESPR | Common Stock | I | 109.1000 | -150,000 | -16,365 | 1,904,594 | ||||
| 2015-04-27 | 2015-04-24 | 4 | Aisling Capital II LP By Aisling Capital II, LP | ESPR | Common Stock | I | 106.1000 | -61,726 | -6,549 | 1,837,125 | ||||
| 2015-04-27 | 2015-04-24 | 4 | Aisling Capital II LP By Aisling Capital II, LP | ESPR | Common Stock | I | 108.0000 | -5,743 | -620 | 1,898,851 | ||||
| 2015-04-27 | 2015-04-23 | 4 | Aisling Capital II LP By Aisling Capital II, L.P. | ESPR | Common Stock | I | 109.1000 | -150,000 | -16,365 | 1,904,594 | ||||
| 2015-03-24 | 2015-03-20 | 4 | DOMAIN PARTERS VII L P | ESPR | Common Stock | D | -350,000 | 2,216,935 | ||||||
| 2015-03-23 | 2015-03-19 | 4 | ENRIGHT PATRICK G By LCA | ESPR | Common Stock | I | 116.0530 | -123 | -14 | 18,361 | ||||
| 2015-03-23 | 2015-03-19 | 4 | ENRIGHT PATRICK G By LCA | ESPR | Common Stock | I | 114.1453 | -44 | -5 | 18,484 | ||||
| 2015-03-23 | 2015-03-19 | 4 | ENRIGHT PATRICK G By LCA | ESPR | Common Stock | I | 113.9185 | -3,907 | -445 | 18,528 | ||||
| 2015-03-23 | 2015-03-19 | 4 | ENRIGHT PATRICK G By LCA | ESPR | Common Stock | I | 111.0594 | -67 | -7 | 22,435 | ||||
| 2015-03-23 | 2015-03-19 | 4 | ENRIGHT PATRICK G By LCA | ESPR | Common Stock | I | 110.0069 | -5,684 | -625 | 22,502 | ||||
| 2015-03-23 | 2015-03-19 | 4 | ENRIGHT PATRICK G By LVP | ESPR | Common Stock | I | 116.0530 | -6,077 | -705 | 916,035 | ||||
| 2015-03-23 | 2015-03-19 | 4 | ENRIGHT PATRICK G By LVP | ESPR | Common Stock | I | 114.1453 | -2,156 | -246 | 922,112 | ||||
| 2015-03-23 | 2015-03-19 | 4 | ENRIGHT PATRICK G By LVP | ESPR | Common Stock | I | 113.9183 | -194,988 | -22,213 | 924,268 | ||||
| 2015-03-23 | 2015-03-19 | 4 | ENRIGHT PATRICK G By LVP | ESPR | Common Stock | I | 111.0590 | -3,353 | -372 | 1,119,256 | ||||
| 2015-03-23 | 2015-03-19 | 4 | ENRIGHT PATRICK G By LVP | ESPR | Common Stock | I | 110.0069 | -283,601 | -31,198 | 1,122,609 | ||||
| 2015-03-20 | 2015-03-18 | 4 | Lalwani Narendra D. | ESPR | Stock option (right to buy) | D | 105.72 | 20,000 | 20,000 | |||||
| 2015-03-20 | 2015-03-18 | 4 | MAYLEBEN TIMOTHY M | ESPR | Stock option (right to buy) | D | 105.72 | 36,800 | 36,800 | |||||
| 2015-03-20 | 2015-03-18 | 4 | NEWTON ROGER S | ESPR | Stock option (right to buy) | D | 105.72 | 8,000 | 8,000 | |||||
| 2015-02-20 | 2015-02-18 | 4 | Alta Partners VIII, L.P. | ESPR | Common Stock | D | -842,222 | 1,709,967 | ||||||
| 2015-02-17 | 2014-12-22 | 5 | MAYLEBEN TIMOTHY M | ESPR | Common Stock | D | -500 | 23,814 | ||||||
| 2015-02-17 | 2013-09-03 | 5 | MAYLEBEN TIMOTHY M | ESPR | Common Stock | D | -4,500 | 24,314 | ||||||
| 2015-01-06 | 2015-01-02 | 4 | NEWTON ROGER S | ESPR | Stock Option (right to buy) | D | 41.23 | 20,000 | 20,000 | |||||
| 2015-01-06 | 2015-01-02 | 4 | MAYLEBEN TIMOTHY M | ESPR | Stock Option (right to buy) | D | 41.23 | 92,000 | 92,000 | |||||
| 2015-01-06 | 2015-01-02 | 4 | Lalwani Narendra D. | ESPR | Stock Option (right to buy) | D | 41.23 | 50,000 | 50,000 | |||||
| 2014-11-19 | 2014-11-18 | 4 | ENRIGHT PATRICK G By LCA | ESPR | Common Stock | I | 32.1313 | -8 | -0 | 28,186 | ||||
| 2014-11-19 | 2014-11-18 | 4 | ENRIGHT PATRICK G By LCA | ESPR | Common Stock | I | 31.5666 | -92 | -3 | 28,194 | ||||
| 2014-11-19 | 2014-11-18 | 4 | ENRIGHT PATRICK G By LVP | ESPR | Common Stock | I | 32.1377 | -412 | -13 | 1,406,210 | ||||
| 2014-11-19 | 2014-11-18 | 4 | ENRIGHT PATRICK G By LVP | ESPR | Common Stock | I | 31.5644 | -4,592 | -145 | 1,406,622 | ||||
| 2014-11-19 | 2014-11-17 | 4 | ENRIGHT PATRICK G By LCA | ESPR | Common Stock | I | 33.7896 | -2,722 | -92 | 28,286 | ||||
| 2014-11-19 | 2014-11-17 | 4 | ENRIGHT PATRICK G By LCA | ESPR | Common Stock | I | 32.9339 | -2,728 | -90 | 31,008 | ||||
| 2014-11-19 | 2014-11-17 | 4 | ENRIGHT PATRICK G By LCA | ESPR | Common Stock | I | 32.0115 | -4,021 | -129 | 33,736 | ||||
| 2014-11-19 | 2014-11-17 | 4 | ENRIGHT PATRICK G By LVP | ESPR | Common Stock | I | 33.7897 | -135,816 | -4,589 | 1,411,214 | ||||
| 2014-11-19 | 2014-11-17 | 4 | ENRIGHT PATRICK G By LVP | ESPR | Common Stock | I | 32.9339 | -136,148 | -4,484 | 1,547,030 | ||||
| 2014-11-19 | 2014-11-17 | 4 | ENRIGHT PATRICK G By LVP | ESPR | Common Stock | I | 32.0115 | -200,591 | -6,421 | 1,683,178 | ||||
| 2014-11-19 | 2014-11-18 | 4 | Longitude Capital Partners, LLC By LCA | ESPR | Common Stock | I | 32.1313 | -8 | -0 | 28,186 | ||||
| 2014-11-19 | 2014-11-18 | 4 | Longitude Capital Partners, LLC By LCA | ESPR | Common Stock | I | 31.5666 | -92 | -3 | 28,194 | ||||
| 2014-11-19 | 2014-11-18 | 4 | Longitude Capital Partners, LLC By LVP | ESPR | Common Stock | I | 32.1377 | -412 | -13 | 1,406,210 | ||||
| 2014-11-19 | 2014-11-18 | 4 | Longitude Capital Partners, LLC By LVP | ESPR | Common Stock | I | 31.5644 | -4,592 | -145 | 1,406,622 | ||||
| 2014-11-19 | 2014-11-17 | 4 | Longitude Capital Partners, LLC By LCA | ESPR | Common Stock | I | 33.7896 | -2,722 | -92 | 28,286 | ||||
| 2014-11-19 | 2014-11-17 | 4 | Longitude Capital Partners, LLC By LCA | ESPR | Common Stock | I | 32.9339 | -2,728 | -90 | 31,008 | ||||
| 2014-11-19 | 2014-11-17 | 4 | Longitude Capital Partners, LLC By LCA | ESPR | Common Stock | I | 32.0115 | -4,021 | -129 | 33,736 | ||||
| 2014-11-19 | 2014-11-17 | 4 | Longitude Capital Partners, LLC By LVP | ESPR | Common Stock | I | 33.7897 | -135,816 | -4,589 | 1,411,214 | ||||
| 2014-11-19 | 2014-11-17 | 4 | Longitude Capital Partners, LLC By LVP | ESPR | Common Stock | I | 32.9339 | -136,148 | -4,484 | 1,547,030 | ||||
| 2014-11-19 | 2014-11-17 | 4 | Longitude Capital Partners, LLC By LVP | ESPR | Common Stock | I | 32.0115 | -200,591 | -6,421 | 1,683,178 | ||||
| 2014-10-21 | 2014-10-21 | 4 | JANNEY DANIEL | ESPR | Common Stock | I | 20.0000 | 500,000 | 10,000 | 2,552,189 | ||||
| 2014-10-21 | 2014-10-21 | 4 | OMENN GILBERT S | ESPR | Common Stock | D | 20.0000 | 5,000 | 100 | 5,000 | ||||
| 2014-10-21 | 2014-10-21 | 4 | DOMAIN PARTERS VII L P | ESPR | Common Stock | D | 20.0000 | 500,000 | 10,000 | 2,566,935 | ||||
| 2014-10-21 | 2014-10-21 | 4 | Alta Partners VIII, L.P. | ESPR | Common Stock | I | 20.0000 | 500,000 | 10,000 | 2,552,189 | ||||
| 2014-10-14 | 2014-10-09 | 4 | ENRIGHT PATRICK G By LCA | ESPR | Common Stock | I | 30.0000 | -19 | -1 | 37,757 | ||||
| 2014-10-14 | 2014-10-09 | 4 | ENRIGHT PATRICK G By LVP | ESPR | Common Stock | I | 30.0000 | -924 | -28 | 1,883,769 | ||||
| 2014-10-14 | 2014-10-09 | 4 | Longitude Capital Partners, LLC By LCA | ESPR | Common Stock | I | 30.0000 | -19 | -1 | 37,757 | ||||
| 2014-10-14 | 2014-10-09 | 4 | Longitude Capital Partners, LLC By LVP | ESPR | Common Stock | I | 30.0000 | -924 | -28 | 1,883,769 | ||||
| 2014-10-09 | 2014-10-07 | 4 | Longitude Capital Partners, LLC By LCA | ESPR | Common Stock | I | 30.0403 | -235 | -7 | 37,776 | ||||
| 2014-10-09 | 2014-10-07 | 4 | Longitude Capital Partners, LLC By LVP | ESPR | Common Stock | I | 30.0402 | -11,692 | -351 | 1,884,693 | ||||
| 2014-10-09 | 2014-10-07 | 4 | ENRIGHT PATRICK G By LCA | ESPR | Common Stock | I | 30.0403 | -235 | -7 | 37,776 | ||||
| 2014-10-09 | 2014-10-07 | 4 | ENRIGHT PATRICK G By LVP | ESPR | Common Stock | I | 30.0402 | -11,692 | -351 | 1,884,693 | ||||
| 2014-08-08 | 2014-08-07 | 4 | OMENN GILBERT S | ESPR | Stock option (right to buy) | D | 15.33 | 20,000 | 20,000 | |||||
| 2014-08-08 | 2014-08-07 | 4 | Lalwani Narendra D. | ESPR | Stock Option (right to buy) | D | 15.33 | 250,000 | 250,000 | |||||
| 2014-05-16 | 2014-05-15 | 4 | VITULLO NICOLE | ESPR | Stock Option (Right to Buy) | D | 14.42 | 5,000 | 5,000 | |||||
| 2014-05-16 | 2014-05-15 | 4 | GOLDSTEIN DOV A MD | ESPR | Stock Option (right to buy) | D | 14.42 | 5,000 | 5,000 | |||||
| 2014-05-16 | 2014-05-15 | 4 | GOTTO ANTONIO M JR MD D PHIL | ESPR | Stock Option (right to buy) | D | 14.42 | 5,000 | 5,000 | |||||
| 2014-05-16 | 2014-05-15 | 4 | MCGOVERN MARK E | ESPR | Stock Option (right to buy) | D | 14.42 | 5,000 | 5,000 | |||||
| 2014-05-16 | 2014-05-15 | 4 | ENRIGHT PATRICK G | ESPR | Stock Option (right to buy) | D | 14.42 | 5,000 | 5,000 | |||||
| 2014-05-16 | 2014-05-15 | 4 | JANNEY DANIEL | ESPR | Stock Option (right to buy) | D | 14.42 | 5,000 | 5,000 | |||||
| 2014-02-28 | 2014-02-26 | 4 | MCGOVERN MARK E | ESPR | Stock Option (right to buy) | D | 15.32 | 20,000 | 20,000 | |||||
| 2014-02-20 | 2013-12-20 | 4 | MAYLEBEN TIMOTHY M | ESPR | Stock Option (right to buy) | D | 12.92 | 40,000 | 40,000 | |||||
| 2014-02-20 | 2013-12-20 | 4 | NEWTON ROGER S | ESPR | Stock Option (right to buy) | D | 12.92 | 20,000 | 20,000 | |||||
| 2013-07-25 | 2013-07-23 | 4 | MAYLEBEN TIMOTHY M | ESPR | Stock Option (right to buy) | D | 17.11 | 190,000 | 190,000 | |||||
| 2013-07-25 | 2013-07-23 | 4 | NEWTON ROGER S | ESPR | Stock Option (right to buy) | D | 17.11 | 90,000 | 90,000 | |||||
| 2013-07-25 | 2013-07-23 | 4 | Rosenberg Noah L. | ESPR | Stock Option (right to buy) | D | 17.11 | 13,500 | 13,500 | |||||
| 2013-07-02 | 2013-07-01 | 4 | VITULLO NICOLE By DP VII Associates, L.P. | ESPR | Warrant to Purchase Common Stock | I | 6.99 | 1,193 | 1,193 | |||||
| 2013-07-02 | 2013-07-01 | 4 | VITULLO NICOLE By DP VII Associates, L.P. | ESPR | Warrant to Purchase Series A Preferred Stock | I | 1.00 | -8,346 | 0 | |||||
| 2013-07-02 | 2013-07-01 | 4 | VITULLO NICOLE By DP VII Associates, L.P. | ESPR | Series A Preferred Stock | I | -30,462 | 0 | ||||||
| 2013-07-02 | 2013-07-01 | 4 | VITULLO NICOLE By Domain Partners VII, L.P. | ESPR | Warrant to Purchase Common Stock | I | 6.99 | 70,042 | 70,042 | |||||
| 2013-07-02 | 2013-07-01 | 4 | VITULLO NICOLE By Domain Partners VII, L.P. | ESPR | Warrant to Purchase Series A Preferred Stock | I | 1.00 | -489,320 | 0 | |||||
| 2013-07-02 | 2013-07-01 | 4 | VITULLO NICOLE By Domain Partners VII, L.P. | ESPR | Series A Preferred Stock | I | -1,786,012 | 0 | ||||||
| 2013-07-02 | 2013-07-01 | 4 | VITULLO NICOLE By DP VII Associates, L.P. | ESPR | Common Stock | I | 14.0000 | 4,791 | 67 | 35,253 | ||||
| 2013-07-02 | 2013-07-01 | 4 | VITULLO NICOLE By DP VII Associates, L.P. | ESPR | Common Stock | I | 30,462 | 30,462 | ||||||
| 2013-07-02 | 2013-07-01 | 4 | VITULLO NICOLE By Domain Partners VII, L.P. | ESPR | Common Stock | I | 14.0000 | 280,923 | 3,933 | 2,066,935 | ||||
| 2013-07-02 | 2013-07-01 | 4 | VITULLO NICOLE By Domain Partners VII, L.P. | ESPR | Common Stock | I | 1,786,012 | 1,786,012 | ||||||
| 2013-07-02 | 2013-07-01 | 4 | SCHOEMAKER KATHLEEN K By DP VII Associates, L.P. | ESPR | Warrant to Purchase Common Stock | I | 6.99 | 1,193 | 1,193 | |||||
| 2013-07-02 | 2013-07-01 | 4 | SCHOEMAKER KATHLEEN K By DP VII Associates, L.P. | ESPR | Warrant to Purchase Series A Preferred Stock | I | 1.00 | -8,346 | 0 | |||||
| 2013-07-02 | 2013-07-01 | 4 | SCHOEMAKER KATHLEEN K By DP VII Associates, L.P. | ESPR | Series A Preferred Stock | I | -30,462 | 0 | ||||||
| 2013-07-02 | 2013-07-01 | 4 | SCHOEMAKER KATHLEEN K By Domain Partners VII, L.P. | ESPR | Warrant to Purchase Common Stock | I | 6.99 | 70,042 | 70,042 | |||||
| 2013-07-02 | 2013-07-01 | 4 | SCHOEMAKER KATHLEEN K By Domain Partners VII, L.P. | ESPR | Warrant to Purchase Series A Preferred Stock | I | 1.00 | -489,320 | 0 | |||||
| 2013-07-02 | 2013-07-01 | 4 | SCHOEMAKER KATHLEEN K By Domain Partners VII, L.P. | ESPR | Series A Preferred Stock | I | -1,786,012 | 0 | ||||||
| 2013-07-02 | 2013-07-01 | 4 | SCHOEMAKER KATHLEEN K By DP VII Associates, L.P. | ESPR | Common Stock | I | 14.0000 | 4,791 | 67 | 35,253 | ||||
| 2013-07-02 | 2013-07-01 | 4 | SCHOEMAKER KATHLEEN K By DP VII Associates, L.P. | ESPR | Common Stock | I | 30,462 | 30,462 | ||||||
| 2013-07-02 | 2013-07-01 | 4 | SCHOEMAKER KATHLEEN K By Domain Partners VII, L.P. | ESPR | Common Stock | I | 14.0000 | 280,923 | 3,933 | 2,066,935 | ||||
| 2013-07-02 | 2013-07-01 | 4 | SCHOEMAKER KATHLEEN K By Domain Partners VII, L.P. | ESPR | Common Stock | I | 1,786,012 | 1,786,012 | ||||||
| 2013-07-02 | 2013-07-01 | 4 | TREU JESSE I By DP VII Associates, L.P. | ESPR | Warrant to Purchase Common Stock | I | 6.99 | 1,193 | 1,193 | |||||
| 2013-07-02 | 2013-07-01 | 4 | TREU JESSE I By DP VII Associates, L.P. | ESPR | Warrant to Purchase Series A Preferred Stock | I | 1.00 | -8,346 | 0 | |||||
| 2013-07-02 | 2013-07-01 | 4 | TREU JESSE I By DP VII Associates, L.P. | ESPR | Series A Preferred Stock | I | -30,462 | 0 | ||||||
| 2013-07-02 | 2013-07-01 | 4 | TREU JESSE I By Domain Partners VII, L.P. | ESPR | Warrant to Purchase Common Stock | I | 6.99 | 70,042 | 70,042 | |||||
| 2013-07-02 | 2013-07-01 | 4 | TREU JESSE I By Domain Partners VII, L.P. | ESPR | Warrant to Purchase Series A Preferred Stock | I | 1.00 | -489,320 | 0 | |||||
| 2013-07-02 | 2013-07-01 | 4 | TREU JESSE I By Domain Partners VII, L.P. | ESPR | Series A Preferred Stock | I | -1,786,012 | 0 | ||||||
| 2013-07-02 | 2013-07-01 | 4 | TREU JESSE I By DP VII Associates, L.P. | ESPR | Common Stock | I | 14.0000 | 4,791 | 67 | 35,253 | ||||
| 2013-07-02 | 2013-07-01 | 4 | TREU JESSE I By DP VII Associates, L.P. | ESPR | Common Stock | I | 30,462 | 30,462 | ||||||
| 2013-07-02 | 2013-07-01 | 4 | TREU JESSE I By Domain Partners VII, L.P. | ESPR | Common Stock | I | 14.0000 | 280,923 | 3,933 | 2,066,935 | ||||
| 2013-07-02 | 2013-07-01 | 4 | TREU JESSE I By Domain Partners VII, L.P. | ESPR | Common Stock | I | 1,786,012 | 1,786,012 | ||||||
| 2013-07-02 | 2013-07-01 | 4 | DOVEY BRIAN H By DP VII Associates, L.P. | ESPR | Warrant to Purchase Common Stock | I | 6.99 | 1,193 | 1,193 | |||||
| 2013-07-02 | 2013-07-01 | 4 | DOVEY BRIAN H By DP VII Associates, L.P. | ESPR | Warrant to Purchase Series A Preferred Stock | I | 1.00 | -8,346 | 0 | |||||
| 2013-07-02 | 2013-07-01 | 4 | DOVEY BRIAN H By DP VII Associates, L.P. | ESPR | Series A Preferred Stock | I | -30,462 | 0 | ||||||
| 2013-07-02 | 2013-07-01 | 4 | DOVEY BRIAN H By Domain Partners VII, L.P. | ESPR | Warrant to Purchase Common Stock | I | 6.99 | 70,042 | 70,042 | |||||
| 2013-07-02 | 2013-07-01 | 4 | DOVEY BRIAN H By Domain Partners VII, L.P. | ESPR | Warrant to Purchase Series A Preferred Stock | I | 1.00 | -489,320 | 0 | |||||
| 2013-07-02 | 2013-07-01 | 4 | DOVEY BRIAN H By Domain Partners VII, L.P. | ESPR | Series A Preferred Stock | I | -1,786,012 | 0 | ||||||
| 2013-07-02 | 2013-07-01 | 4 | DOVEY BRIAN H By DP VII Associates, L.P. | ESPR | Common Stock | I | 14.0000 | 4,791 | 67 | 35,253 | ||||
| 2013-07-02 | 2013-07-01 | 4 | DOVEY BRIAN H By DP VII Associates, L.P. | ESPR | Common Stock | I | 30,462 | 30,462 | ||||||
| 2013-07-02 | 2013-07-01 | 4 | DOVEY BRIAN H By Domain Partners VII, L.P. | ESPR | Common Stock | I | 14.0000 | 280,923 | 3,933 | 2,066,935 | ||||
| 2013-07-02 | 2013-07-01 | 4 | DOVEY BRIAN H By Domain Partners VII, L.P. | ESPR | Common Stock | I | 1,786,012 | 1,786,012 | ||||||
| 2013-07-02 | 2013-07-01 | 4 | Halak Brian K By DP VII Associates, L.P. | ESPR | Warrant to Purchase Common Stock | I | 6.99 | 1,193 | 1,193 | |||||
| 2013-07-02 | 2013-07-01 | 4 | Halak Brian K By DP VII Associates, L.P. | ESPR | Warrant to Purchase Series A Preferred Stock | I | 1.00 | -8,346 | 0 | |||||
| 2013-07-02 | 2013-07-01 | 4 | Halak Brian K By DP VII Associates, L.P. | ESPR | Series A Preferred Stock | I | -30,462 | 0 | ||||||
| 2013-07-02 | 2013-07-01 | 4 | Halak Brian K By Domain Partners VII, L.P. | ESPR | Warrant to Purchase Common Stock | I | 6.99 | 70,042 | 70,042 | |||||
| 2013-07-02 | 2013-07-01 | 4 | Halak Brian K By Domain Partners VII, L.P. | ESPR | Warrant to Purchase Series A Preferred Stock | I | 1.00 | -489,320 | 0 | |||||
| 2013-07-02 | 2013-07-01 | 4 | Halak Brian K By Domain Partners VII, L.P. | ESPR | Series A Preferred Stock | I | -1,786,012 | 0 | ||||||
| 2013-07-02 | 2013-07-01 | 4 | Halak Brian K By DP VII Associates, L.P. | ESPR | Common Stock | I | 14.0000 | 4,791 | 67 | 35,253 | ||||
| 2013-07-02 | 2013-07-01 | 4 | Halak Brian K By DP VII Associates, L.P. | ESPR | Common Stock | I | 30,462 | 30,462 | ||||||
| 2013-07-02 | 2013-07-01 | 4 | Halak Brian K By Domain Partners VII, L.P. | ESPR | Common Stock | I | 14.0000 | 280,923 | 3,933 | 2,066,935 | ||||
| 2013-07-02 | 2013-07-01 | 4 | Halak Brian K By Domain Partners VII, L.P. | ESPR | Common Stock | I | 1,786,012 | 1,786,012 | ||||||
| 2013-07-02 | 2013-07-01 | 4 | BLAIR JAMES C By DP VII Associates, L.P. | ESPR | Warrant to Purchase Common Stock | I | 6.99 | 1,193 | 1,193 | |||||
| 2013-07-02 | 2013-07-01 | 4 | BLAIR JAMES C By DP VII Associates, L.P. | ESPR | Warrant to Purchase Series A Preferred Stock | I | 1.00 | -8,346 | 0 | |||||
| 2013-07-02 | 2013-07-01 | 4 | BLAIR JAMES C By DP VII Associates, L.P. | ESPR | Series A Preferred Stock | I | -30,462 | 0 | ||||||
| 2013-07-02 | 2013-07-01 | 4 | BLAIR JAMES C By Domain Partners VII, L.P. | ESPR | Warrant to Purchase Common Stock | I | 6.99 | 70,042 | 70,042 | |||||
| 2013-07-02 | 2013-07-01 | 4 | BLAIR JAMES C By Domain Partners VII, L.P. | ESPR | Warrant to Purchase Series A Preferred Stock | I | 1.00 | -489,320 | 0 | |||||
| 2013-07-02 | 2013-07-01 | 4 | BLAIR JAMES C By Domain Partners VII, L.P. | ESPR | Series A Preferred Stock | I | -1,786,012 | 0 | ||||||
| 2013-07-02 | 2013-07-01 | 4 | BLAIR JAMES C By DP VII Associates, L.P. | ESPR | Common Stock | I | 14.0000 | 4,791 | 67 | 35,253 | ||||
| 2013-07-02 | 2013-07-01 | 4 | BLAIR JAMES C By DP VII Associates, L.P. | ESPR | Common Stock | I | 30,462 | 30,462 | ||||||
| 2013-07-02 | 2013-07-01 | 4 | BLAIR JAMES C By Domain Partners VII, L.P. | ESPR | Common Stock | I | 14.0000 | 280,923 | 3,933 | 2,066,935 | ||||
| 2013-07-02 | 2013-07-01 | 4 | BLAIR JAMES C By Domain Partners VII, L.P. | ESPR | Common Stock | I | 1,786,012 | 1,786,012 | ||||||
| 2013-07-02 | 2013-07-01 | 4 | DOMAIN PARTERS VII L P | ESPR | Warrant to Purchase Common Stock | D | 6.99 | 70,042 | 70,042 | |||||
| 2013-07-02 | 2013-07-01 | 4 | DOMAIN PARTERS VII L P | ESPR | Warrant to Purchase Series A Preferred Stock | D | 1.00 | -489,320 | 0 | |||||
| 2013-07-02 | 2013-07-01 | 4 | DOMAIN PARTERS VII L P | ESPR | Series A Preferred Stock | D | -1,786,012 | 0 | ||||||
| 2013-07-02 | 2013-07-01 | 4 | DOMAIN PARTERS VII L P | ESPR | Common Stock | D | 14.0000 | 280,923 | 3,933 | 2,066,935 | ||||
| 2013-07-02 | 2013-07-01 | 4 | DOMAIN PARTERS VII L P | ESPR | Common Stock | D | 1,786,012 | 1,786,012 | ||||||
| 2013-07-02 | 2013-07-01 | 4 | DP VII ASSOCIATES LP | ESPR | Warrant to Purchase Common Stock | D | 6.99 | 1,193 | 1,193 | |||||
| 2013-07-02 | 2013-07-01 | 4 | DP VII ASSOCIATES LP | ESPR | Warrant to Purchase Series A Preferred Stock | D | 1.00 | -8,346 | 0 | |||||
| 2013-07-02 | 2013-07-01 | 4 | DP VII ASSOCIATES LP | ESPR | Series A Preferred Stock | D | -30,462 | 0 | ||||||
| 2013-07-02 | 2013-07-01 | 4 | DP VII ASSOCIATES LP | ESPR | Common Stock | D | 14.0000 | 4,791 | 67 | 35,253 | ||||
| 2013-07-02 | 2013-07-01 | 4 | DP VII ASSOCIATES LP | ESPR | Common Stock | D | 30,462 | 30,462 | ||||||
| 2013-07-01 | 2013-07-01 | 4 | Aisling Capital II LP By Aisling Capital II, L.P. | ESPR | Warrant to Purchase Common Stock | I | 6.99 | 71,237 | 71,237 | |||||
| 2013-07-01 | 2013-07-01 | 4 | Aisling Capital II LP By Aisling Capital II, L.P. | ESPR | Warrant to Purchase Preferred Stock | I | 1.00 | -497,666 | 0 | |||||
| 2013-07-01 | 2013-07-01 | 4 | Aisling Capital II LP By Aisling Capital II, L.P. | ESPR | Series A Preferred Stock | I | -1,816,475 | 0 | ||||||
| 2013-07-01 | 2013-07-01 | 4 | Aisling Capital II LP By Aisling Capital II, L.P. | ESPR | Common Stock | I | 14.0000 | 238,119 | 3,334 | 2,054,594 | ||||
| 2013-07-01 | 2013-07-01 | 4 | Aisling Capital II LP By Aisling Capital II, L.P. | ESPR | Common Stock | I | 1,816,475 | 1,816,475 | ||||||
| 2013-07-01 | 2013-07-01 | 4 | Alta Partners VIII, L.P. | ESPR | Warrant to Purchase Common Stock | I | 6.99 | 71,237 | 71,237 | |||||
| 2013-07-01 | 2013-07-01 | 4 | Alta Partners VIII, L.P. | ESPR | Warrant to Purchase Preferred Stock | I | 1.00 | -497,666 | 0 | |||||
| 2013-07-01 | 2013-07-01 | 4 | Alta Partners VIII, L.P. | ESPR | Series A Preferred Stock | I | -1,816,475 | 0 | ||||||
| 2013-07-01 | 2013-07-01 | 4 | Alta Partners VIII, L.P. | ESPR | Common Stock | I | 14.0000 | 235,714 | 3,300 | 2,052,189 | ||||
| 2013-07-01 | 2013-07-01 | 4 | Alta Partners VIII, L.P. | ESPR | Common Stock | I | 1,816,475 | 1,816,475 | ||||||
| 2013-07-01 | 2013-07-01 | 4 | JANNEY DANIEL By Alta Partners VIII, L.P. | ESPR | Warrant to Purchase Common Stock | I | 6.99 | 71,237 | 71,237 | |||||
| 2013-07-01 | 2013-07-01 | 4 | JANNEY DANIEL By Alta Partners VIII, L.P. | ESPR | Warrant to Purchase Preferred Stock | I | 1.00 | -497,666 | 0 | |||||
| 2013-07-01 | 2013-07-01 | 4 | JANNEY DANIEL By Alta Partners VIII, L.P. | ESPR | Series A Preferred Stock | I | -1,816,475 | 0 | ||||||
| 2013-07-01 | 2013-07-01 | 4 | JANNEY DANIEL By Alta Partners VIII, L.P. | ESPR | Common Stock | I | 14.0000 | 235,714 | 3,300 | 2,052,189 | ||||
| 2013-07-01 | 2013-07-01 | 4 | JANNEY DANIEL By Alta Partners VIII, L.P. | ESPR | Common Stock | I | 1,816,475 | 1,816,475 | ||||||
| 2013-07-01 | 2013-07-01 | 4 | ENRIGHT PATRICK G | ESPR | Stock Option (right to buy) | D | 14.00 | 21,471 | 21,471 | |||||
| 2013-07-01 | 2013-07-01 | 4 | ENRIGHT PATRICK G By Longitude Capital Associates, L.P. | ESPR | Series A Preferred Stock | I | -33,753 | 0 | ||||||
| 2013-07-01 | 2013-07-01 | 4 | ENRIGHT PATRICK G By Longitude Venture Partners, L.P. | ESPR | Series A Preferred Stock | I | -1,683,967 | 0 | ||||||
| 2013-07-01 | 2013-07-01 | 4 | ENRIGHT PATRICK G By Longitude Capital Associates, L.P. | ESPR | Common Stock | I | 14.0000 | 4,258 | 60 | 38,011 | ||||
| 2013-07-01 | 2013-07-01 | 4 | ENRIGHT PATRICK G By Longitude Venture Partners, L.P. | ESPR | Common Stock | I | 14.0000 | 212,418 | 2,974 | 1,896,385 | ||||
| 2013-07-01 | 2013-07-01 | 4 | ENRIGHT PATRICK G By Longitude Capital Associates, L.P. | ESPR | Common Stock | I | 33,753 | 33,753 | ||||||
| 2013-07-01 | 2013-07-01 | 4 | ENRIGHT PATRICK G By Longitude Venture Partners, L.P. | ESPR | Common Stock | I | 1,683,967 | 1,683,967 | ||||||
| 2013-07-01 | 2013-07-01 | 4 | GOLDSTEIN DOV A MD By Aisling Capital II, L.P. | ESPR | Warrant to Purchase Common Stock | I | 6.99 | 71,237 | 71,237 | |||||
| 2013-07-01 | 2013-07-01 | 4 | GOLDSTEIN DOV A MD By Aisling Capital II, L.P. | ESPR | Warrant to Purchase Preferred Stock | I | 1.00 | -497,666 | 0 | |||||
| 2013-07-01 | 2013-07-01 | 4 | GOLDSTEIN DOV A MD By Aisling Capital II, L.P. | ESPR | Series A Preferred Stock | I | -1,816,475 | 0 | ||||||
| 2013-07-01 | 2013-07-01 | 4 | GOLDSTEIN DOV A MD By Aisling Capital II, LP | ESPR | Common Stock | I | 14.0000 | 238,119 | 3,334 | 2,054,594 | ||||
| 2013-07-01 | 2013-07-01 | 4 | GOLDSTEIN DOV A MD By Aisling Capital II, LP | ESPR | Common Stock | I | 1,816,475 | 1,816,475 | ||||||
| 2013-07-01 | 2013-07-01 | 4 | LANGE LOUIS G By Asset Management Company Venture Fund, L.P. | ESPR | Warrant to Purchase Common Stock | I | 6.99 | 7,333 | 7,333 | |||||
| 2013-07-01 | 2013-07-01 | 4 | LANGE LOUIS G By Asset Management Company Venture Fund, L.P. | ESPR | Warrant to Purchase Preferred Stock | I | 1.00 | -51,230 | 0 | |||||
| 2013-07-01 | 2013-07-01 | 4 | LANGE LOUIS G | ESPR | Series A Preferred Stock | D | -14,314 | 0 | ||||||
| 2013-07-01 | 2013-07-01 | 4 | LANGE LOUIS G By Asset Management Company Venture Fund, L.P. | ESPR | Series A Preferred Stock | I | -186,989 | 0 | ||||||
| 2013-07-01 | 2013-07-01 | 4 | LANGE LOUIS G By Asset Management Company Venture Fund, L.P. | ESPR | Common Stock | I | 14.0000 | 10,714 | 150 | 197,703 | ||||
| 2013-07-01 | 2013-07-01 | 4 | LANGE LOUIS G | ESPR | Common Stock | D | 14.0000 | 3,500 | 49 | 17,814 | ||||
| 2013-07-01 | 2013-07-01 | 4 | LANGE LOUIS G | ESPR | Common Stock | D | 14,314 | 14,314 | ||||||
| 2013-07-01 | 2013-07-01 | 4 | LANGE LOUIS G By Asset Management Company Venture Fund, L.P. | ESPR | Common Stock | I | 186,989 | 186,989 | ||||||
| 2013-07-01 | 2013-07-01 | 4 | NEWTON ROGER S | ESPR | Warrant to Purchase Common Stock | D | 6.99 | 34,651 | 34,651 | |||||
| 2013-07-01 | 2013-07-01 | 4 | NEWTON ROGER S | ESPR | Warrant to Purchase Preferred Stock | D | 1.00 | -242,082 | 0 | |||||
| 2013-07-01 | 2013-07-01 | 4 | NEWTON ROGER S | ESPR | Series A Preferred Stock | D | -301,051 | 0 | ||||||
| 2013-07-01 | 2013-07-01 | 4 | NEWTON ROGER S | ESPR | Common Stock | D | 14.0000 | 42,346 | 593 | 629,683 | ||||
| 2013-07-01 | 2013-07-01 | 4 | NEWTON ROGER S | ESPR | Common Stock | D | 301,051 | 587,337 | ||||||
| 2013-07-01 | 2013-07-01 | 4 | MAYLEBEN TIMOTHY M | ESPR | Common Stock | D | 14.0000 | 5,000 | 70 | 28,814 | ||||
| 2013-07-01 | 2013-07-01 | 4 | Longitude Capital Partners, LLC By Longitude Capital Associates, L.P. | ESPR | Series A Preferred Stock | I | -33,753 | 0 | ||||||
| 2013-07-01 | 2013-07-01 | 4 | Longitude Capital Partners, LLC By Longitude Venture Partners, L.P. | ESPR | Series A Preferred Stock | I | -1,683,967 | 0 | ||||||
| 2013-07-01 | 2013-07-01 | 4 | Longitude Capital Partners, LLC By Longitude Capital Associates, L.P. | ESPR | Common Stock | I | 14.0000 | 4,258 | 60 | 38,011 | ||||
| 2013-07-01 | 2013-07-01 | 4 | Longitude Capital Partners, LLC By Longitude Venture Partners, L.P. | ESPR | Common Stock | I | 14.0000 | 212,418 | 2,974 | 1,896,385 | ||||
| 2013-07-01 | 2013-07-01 | 4 | Longitude Capital Partners, LLC By Longitude Capital Associates, L.P. | ESPR | Common Stock | I | 33,753 | 33,753 | ||||||
| 2013-07-01 | 2013-07-01 | 4 | Longitude Capital Partners, LLC By Longitude Venture Partners, L.P. | ESPR | Common Stock | I | 1,683,967 | 1,683,967 | ||||||
| 2013-06-25 | 3 | DOVEY BRIAN H By Domain Associates, LLC | ESPR | Common Stock | I | 21,471 | ||||||||
| 2013-06-25 | 3 | BLAIR JAMES C By Domain Associates, LLC | ESPR | Common Stock | I | 21,471 | ||||||||
| 2013-06-25 | 3 | SCHOEMAKER KATHLEEN K By Domain Associates, LLC | ESPR | Common Stock | I | 21,471 | ||||||||
| 2013-06-25 | 3 | VITULLO NICOLE By Domain Associates, LLC | ESPR | Common Stock | I | 21,471 | ||||||||
| 2013-06-25 | 3 | TREU JESSE I By Domain Associates, LLC | ESPR | Common Stock | I | 21,471 | ||||||||
| 2013-06-25 | 3 | DOMAIN ASSOCIATES | ESPR | Common Stock | D | 21,471 | ||||||||
| 2013-06-25 | 3 | Halak Brian K By Domain Associates, LLC | ESPR | Common Stock | I | 21,471 | ||||||||
| 2013-06-25 | 3 | NEWTON ROGER S | ESPR | Common Stock | D | 286,286 | ||||||||
| 2013-06-25 | 3 | MAYLEBEN TIMOTHY M | ESPR | Common Stock | D | 23,814 | ||||||||
| 2013-06-25 | 3 | Kamdar Kim P. By Domain Associates, LLC | ESPR | Common Stock | I | 21,471 |
P
Pembelian sekuritas non-derivatif atau derivatif di pasar terbuka atau secara pribadi.
S
Penjualan terbuka atau penjualan pribadi atas sekuritas non-derivatif atau derivatif.
A
Hibah, penghargaan, atau perolehan sekuritas lainnya dari perusahaan (seperti opsi)
C
Konversi turunan
D
Penjualan atau pengalihan sekuritas kembali ke perusahaan.
F
Pembayaran harga pelaksanaan atau kewajiban pajak menggunakan sebagian sekuritas yang diterima dari perusahaan.
G
Pemberian sekuritas oleh atau kepada orang dalam.
K
Swap ekuitas dan transaksi lindung nilai serupa
M
Pelaksanaan atau konversi sekuritas derivatif yang diterima dari perusahaan (seperti opsi)
V
Transaksi yang dilaporkan secara sukarela pada Formulir 4.
J
Lainnya (disertai dengan catatan kaki yang menjelaskan transaksi tersebut)
