PRLD Insider Trading - Prelude Therapeutics Incorporated

Jumlah Saham Beredar	43,750,086 shares
Saham Orang Dalam	35,531,914 shares
Kepemilikan oleh Orang Dalam	81.22 %
Orang Dalam Sejati	21

Skor Sentimen Orang Dalam

Skor Sentimen Orang Dalam mengidentifikasi perusahaan yang dibeli oleh orang dalam korporat.

Ini adalah hasil dari model kuantitatif multifaktor yang canggih yang mengidentifikasi perusahaan dengan tingkat akumulasi internal tertinggi. Model penilaian ini menggunakan kombinasi dari jumlah bersih orang dalam yang membeli dalam 90 hari sebelumnya, total saham yang dibeli sebagai persentase dari jumlah saham yang beredar, dan total saham yang dimiliki oleh orang dalam. Angka tersebut berkisar dari 0 hingga 100, dengan angka yang lebih tinggi menunjukkan tingkat akumulasi yang lebih tinggi dibandingkan dengan perusahaan sejenis, dan 50 adalah rata-rata.

Frekuensi Pembaruan: Setiap Hari

Lihat Pilihan Teratas dari Orang Dalam, yang menyediakan daftar perusahaan dengan akumulasi orang dalam tertinggi.

Lihat Saham dengan Peringkat Tertinggi

Skor Sentimen Petugas

Skor Sentimen Pejabat menemukan perusahaan yang dibeli oleh Pejabat Korporat.

Menurut definisi, Pejabat Korporasi adalah Orang Dalam Korporasi, tetapi tidak seperti beberapa Orang Dalam lainnya (Pemegang Saham 10% dan Anggota Dewan), Pejabat bekerja untuk perusahaan setiap hari, dan mereka menggunakan uang mereka sendiri saat bertransaksi . (Pemegang Saham 10% dan Anggota Dewan seringkali adalah manajer dana yang mengelola uang orang lain.) Dengan demikian, transaksi orang dalam yang dilakukan oleh Pejabat jauh lebih signifikan dan harus ditangani dengan tepat.

Seperti Skor Sentimen Internal, Skor Sentimen Pejabat adalah hasil dari model kuantitatif multi-faktor yang canggih yang mengidentifikasi perusahaan dengan tingkat akumulasi pejabat tertinggi.

Frekuensi Pembaruan: Setiap Hari

Lihat Pilihan Teratas dari Orang Dalam, yang menyediakan daftar perusahaan dengan sentimen orang dalam tertinggi.

Lihat Saham dengan Peringkat Tertinggi

Metrik Utama Orang Dalam

Kartu ini menunjukkan peringkat perusahaan berdasarkan berbagai metrik internal. Peringkat persentil menunjukkan bagaimana perusahaan ini dibandingkan dengan perusahaan lain di pasar AS. Peringkat yang lebih tinggi menunjukkan situasi yang lebih baik.

Sebagai contoh, secara umum diterima bahwa pembelian oleh orang dalam perusahaan adalah indikator positif, sehingga perusahaan dengan lebih banyak pembelian oleh orang dalam akan mendapat peringkat lebih tinggi daripada perusahaan dengan lebih sedikit pembelian oleh orang dalam (atau bahkan penjualan oleh orang dalam).

Jumlah Bersih Pembelian oleh Orang Dalam (Peringkat)

0 ( )

1596 out of 11305

Jumlah Bersih Pembelian oleh Orang Dalam adalah total jumlah orang dalam yang membeli dikurangi total jumlah orang dalam yang menjual dalam 90 hari terakhir. Peringkat persentil ditunjukkan di sini (kisaran dari 0 hingga 100%).

Persentase Saham yang Dibeli oleh Orang Dalam (Peringkat)

0.000 %( )

1589 out of 11224

Persentase Saham yang Dibeli oleh Orang Dalam adalah total jumlah saham yang dibeli oleh orang dalam dikurangi total jumlah saham yang dijual oleh orang dalam dalam 90 hari terakhir, dibagi dengan total jumlah saham yang beredar dan dikalikan dengan 100.

Grafik Perdagangan Orang Dalam

Grafik berikut menunjukkan Prelude Therapeutics Incorporated transaksi orang dalam. Orang dalam adalah pejabat, direktur, atau investor signifikan dalam suatu perusahaan. Secara umum, melakukan transaksi di perusahaan mereka berdasarkan informasi material yang belum dipublikasikan adalah ilegal bagi orang dalam. Ini tidak berarti bahwa mereka dilarang melakukan transaksi apa pun di perusahaan mereka sendiri. Namun, mereka wajib melaporkan semua transaksi kepada SEC melalui Formulir 4.

Daftar Orang Dalam dan Metrik Profitabilitas

Tabel ini menampilkan daftar orang dalam yang diketahui, dan dibuat secara otomatis dari pengajuan yang diungkapkan kepada SEC. Selain nama, jabatan terbaru, dan sebutan direktur, pejabat, atau pemilik 10%, kami memberikan kepemilikan terbaru yang diungkapkan. Selain itu, jika memungkinkan, kami memberikan kinerja perdagangan historis untuk orang dalam tersebut. Kinerja perdagangan historis adalah rata-rata tertimbang dari kinerja transaksi pembelian pasar terbuka aktual yang dilakukan oleh orang dalam tersebut. Untuk informasi lebih lanjut tentang bagaimana ini dihitung, tonton webinar YouTube ini.

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Orang Dalam	Saham Dimiliki	Terbagi Disesuaikan
Baker Bros. Advisors Lp Director, 10% Owner - [D] [10%]	9,252,951	9,252,951
Julian Baker Director, 10% Owner - [D] [10%]	9,252,951	9,252,951
Martin Babler	36,400
David P Bonita Director, 10% Owner - [D] [10%]	10,646,056	10,646,056
Laurent Chardonnet Chief Financial Officer - [O]	42,165	42,165
Andrew Combs Chief Chemistry Officer - [O]	480,123	480,123
Mardi Dier Director - [D]	10,000	10,000

Orang Dalam	Saham Dimiliki	Terbagi Disesuaikan
Paul A Friedman Director - [D]	500,098	500,098
Jane Huang President, CMO - [O]	80,897	80,897
Bryant David Lim CLO, Interim CFO, Corp Sec. - [O]	27,400	27,400
David J Mauro Chief Medical Officer - [O]	0	0
Deborah Morosini EVP, Chief of Clinical Affairs - [O]	444	444
Kelvin Neu	0
Orbimed Advisors Llc Director, 10% Owner - [D] [10%]	10,646,056	10,646,056

Orang Dalam	Saham Dimiliki	Terbagi Disesuaikan
Orbimed Capital Llc Director, 10% Owner - [D] [10%]	5,596,886	10,646,056
OrbiMed Capital GP VI LLC Director, 10% Owner - [D] [10%]	5,596,886	10,646,056
Christopher Pierce EVP and Chief of Business Oper - [O]	3,750	3,750
Brian Piper Chief Financial Officer - [O]	0	0
Victor Sandor	11,206
Peggy Scherle Chief Scientific Officer - [O]	172,920	172,920
Krishna Vaddi CEO, Director - [D] [O]	3,669,054	3,669,054

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Rekam Jejak Pembelian Orang Dalam - Analisis Keuntungan Jangka Pendek

Pada bagian ini, kami menganalisis profitabilitas setiap pembelian saham oleh orang dalam di pasar terbuka yang tidak direncanakan yang dilakukan di PRLD / Prelude Therapeutics Incorporated. Analisis ini membantu memahami apakah orang dalam tersebut secara konsisten menghasilkan pengembalian abnormal, dan layak untuk diikuti. Analisis ini dilakukan selama satu tahun setelah setiap transaksi, dan hasilnya bersifat teoretis .

Tabel berikut menunjukkan pembelian pasar terbuka terbaru yang bukan bagian dari rencana perdagangan otomatis.

Tanggal Perdagangan	Orang Dalam	Dilaporkan Saham	Dilaporkan Harga	Disesuaikan Saham	Disesuaikan Harga	Dasar Biaya	Hari-hari menuju Maksimal	Harga di Maksimal	Maksimal Keuntungan ($)	Maksimum Pengembalian (%)
2025-03-25	Combs Andrew	100,000	0.6925	100,000	0.6925	69,250	156	1.3100	61,750	89.17
2025-03-25	Vaddi Krishna	675,000	0.6925	675,000	0.6925	467,438
2025-03-21	Vaddi Krishna	15,000	0.7306	15,000	0.7306	10,959
2025-03-20	Vaddi Krishna	5,416	0.7294	5,416	0.7294	3,950
2025-03-17	Vaddi Krishna	9,106	0.7499	9,106	0.7499	6,829
2025-03-14	Vaddi Krishna	29,999	0.7544	29,999	0.7544	22,631
2025-03-13	Vaddi Krishna	50,000	0.7164	50,000	0.7164	35,820
2025-03-12	Vaddi Krishna	47,500	0.7104	47,500	0.7104	33,744
2024-12-31	Vaddi Krishna	5,000	1.2087	5,000	1.2087	6,044

Harga yang Disesuaikan adalah harga yang disesuaikan dengan pemisahan saham. Ang Adjusted Shares ay ang jumlah saham yang disesuaikan dengan pemisahan saham (stock split).

PRLD / Prelude Therapeutics Incorporated Insider Trades

Rekam Jejak Penjualan Orang Dalam - Analisis Kerugian Jangka Pendek

Dalam bagian ini, kami menganalisis penghindaran kerugian jangka pendek dari setiap penjualan dalam pasar terbuka yang tidak direncanakan oleh orang dalam yang dilakukan di PRLD / Prelude Therapeutics Incorporated. Pola penghindaran kerugian yang konsisten dapat menunjukkan bahwa transaksi penjualan di masa mendatang dapat memprediksi penurunan harga. Analisis ini berlaku untuk satu tahun setelah setiap perdagangan, dan hasilnya bersifat teoretis .

Tabel berikut menunjukkan penjualan pasar terbuka terbaru yang bukan bagian dari rencana perdagangan otomatis.

Tanggal Perdagangan	Orang Dalam	Dilaporkan Saham	Dilaporkan Harga	Disesuaikan Saham	Disesuaikan Harga	Dasar Biaya	Hari-hari menuju Menit	Harga di Menit	Kerugian Maksimal Dihindari ($)	Kerugian Maksimal Dihindari (%)
2023-04-06	Huang Jane	13,280	6.1200	13,280	6.1200	81,274	208	1.6900	-58,830	-72.39

Harga yang Disesuaikan adalah harga yang disesuaikan dengan pemisahan saham. Ang Adjusted Shares ay ang jumlah saham yang disesuaikan dengan pemisahan saham (stock split).

Riwayat Transaksi

Klik ikon tautan untuk melihat riwayat transaksi lengkap. Transaksi yang dilaporkan sebagai bagian dari rencana perdagangan otomatis 10b5-1 akan memiliki tanda X di kolom yang bertanda 10b-5.

Berkas Tanggal	Perdagangan Tanggal	Formulir	Orang Dalam	Ticker	Judul Keamanan	Kode	Langsung	Latihan Harga	Satuan Harga	Unit Diubah	Nilai Diubah (1 ribu)	Sisa Pilihan	Sisa Saham
2025-07-08	2025-07-04	4	Huang Jane	PRLD	Common Stock	F - Taxes	D		0.7939	-3,355	-3		80,897
2025-07-08	2025-07-04	4	Huang Jane	PRLD	Common Stock	M - Exercise	D			9,375			84,252
2025-04-07	2025-04-04	4	Huang Jane	PRLD	Common Stock	F - Taxes	D		0.6750	-3,355	-2		74,877
2025-04-07	2025-04-04	4	Huang Jane	PRLD	Common Stock	M - Exercise	D			9,375			78,232
2025-03-27	2025-03-25	4	Combs Andrew	PRLD	Common Stock	P - Purchase	D		0.6925	100,000	69		480,123
2025-03-27	2025-03-25	4	Vaddi Krishna	PRLD	Common Stock	P - Purchase	D		0.6925	675,000	467		1,999,296
2025-03-24	2025-03-21	4	Vaddi Krishna	PRLD	Common Stock	P - Purchase	D		0.7306	15,000	11		1,324,296
2025-03-24	2025-03-20	4	Vaddi Krishna	PRLD	Common Stock	P - Purchase	D		0.7294	5,416	4		1,309,296
2025-03-18	2025-03-17	4	Vaddi Krishna	PRLD	Common Stock	P - Purchase	D		0.7499	9,106	7		1,303,880
2025-03-18	2025-03-14	4	Vaddi Krishna	PRLD	Common Stock	P - Purchase	D		0.7544	29,999	23		1,294,774
2025-03-14	2025-03-13	4	Vaddi Krishna	PRLD	Common Stock	P - Purchase	D		0.7164	50,000	36		1,264,775
2025-03-14	2025-03-12	4	Vaddi Krishna	PRLD	Common Stock	P - Purchase	D		0.7104	47,500	34		1,214,775
2025-01-07	2025-01-04	4	Huang Jane	PRLD	Common Stock	F - Taxes	D		1.3900	-3,859	-5		68,857
2025-01-07	2025-01-04	4	Huang Jane	PRLD	Common Stock	M - Exercise	D			9,375			72,716
2025-01-03	2024-12-31	4	Vaddi Krishna	PRLD	Common Stock	P - Purchase	I		1.2087	5,000	6		142,553
2025-01-02	2024-12-30	4	Vaddi Krishna	PRLD	Common Stock	P - Purchase	I		1.2000	10,000	12		137,553
2024-12-26	2024-12-23	4	Combs Andrew	PRLD	Common Stock	P - Purchase	D		1.3667	60,000	82		377,623
2024-12-26	2024-12-20	4	Combs Andrew	PRLD	Common Stock	P - Purchase	D		1.1500	3,075	4		317,623
2024-12-20	2024-12-19	4	Lim Bryant David	PRLD	Common Stock	P - Purchase	D		0.9055	25,000	23		27,400
2024-12-20	2024-12-19	4	Vaddi Krishna	PRLD	Common Stock	P - Purchase	I		0.8879	6,888	6		127,553
2024-12-20	2024-12-18	4	Vaddi Krishna	PRLD	Common Stock	P - Purchase	D		0.9321	100,000	93		1,167,275
2024-10-07	2024-10-04	4	Huang Jane	PRLD	Common Stock	F - Taxes	D		2.0000	-3,349	-7		63,341
2024-10-07	2024-10-04	4	Huang Jane	PRLD	Common Stock	M - Exercise	D			9,375			66,690
2024-07-08	2024-07-04	4	Huang Jane	PRLD	Common Stock	F - Taxes	D		3.6000	-3,347	-12		57,315
2024-07-08	2024-07-04	4	Huang Jane	PRLD	Common Stock	M - Exercise	D			9,375			60,662
2024-04-08	2024-04-04	4	Huang Jane	PRLD	Common Stock	F - Taxes	D		4.7400	-3,347	-16		51,287
2024-04-08	2024-04-04	4	Huang Jane	PRLD	Common Stock	M - Exercise	D			9,375			54,634
2024-01-08	2024-01-04	4	Huang Jane	PRLD	Common Stock	F - Taxes	D		3.7700	-3,844	-14		45,259
2024-01-08	2024-01-04	4	Huang Jane	PRLD	Common Stock	M - Exercise	D			9,375			49,103
2023-10-06	2023-10-04	4	Huang Jane	PRLD	Common Stock	M - Exercise	D			9,375			39,728
2023-07-06	2023-07-04	4	Huang Jane	PRLD	Common Stock	F - Taxes	D		4.6500	-3,242	-15		30,353
2023-07-06	2023-07-04	4	Huang Jane	PRLD	Common Stock	M - Exercise	D			9,375			33,595
2023-05-26	2023-05-25	4	Vaddi Krishna	PRLD	Common Stock	P - Purchase	D		5.3100	900	5		1,067,275
2023-05-26	2023-05-24	4	Vaddi Krishna	PRLD	Common Stock	P - Purchase	D		5.0114	1,000	5		1,066,375
2023-05-25	2023-05-23	4	Chardonnet Laurent	PRLD	Common Stock	P - Purchase	D		5.5000	5,000	28		42,165
2023-05-25	2023-05-24	4	Lim Bryant David	PRLD	Common Stock	P - Purchase	D		5.3900	2,400	13		2,400
2023-05-25	2023-05-23	4	Vaddi Krishna	PRLD	Common Stock	P - Purchase	D		5.6300	11,856	67		1,065,375
2023-05-24	2023-05-22	4	ORBIMED ADVISORS LLC See footnotes	PRLD	Common Stock	P - Purchase	I		5.7500	869,565	5,000		10,119,756
2023-05-24	2023-05-22	4	Bonita David P See footnotes	PRLD	Common Stock	P - Purchase	I		5.7500	869,565	5,000		10,119,756
2023-04-06	2023-04-06	4	Huang Jane	PRLD	Common Stock	S - Sale	D		6.1200	-13,280	-81		24,220
2023-04-06	2023-04-04	4	Huang Jane	PRLD	Common Stock	M - Exercise	D			37,500			37,500
2022-12-21	2022-12-20	4	Vaddi Krishna	PRLD	Common Stock	P - Purchase	I		5.1306	19,188	98		120,665
2022-12-12	2022-12-08	4	Chardonnet Laurent	PRLD	Common Stock	P - Purchase	D		4.7600	10,000	48		35,873
2022-06-01	2022-06-01	4	Chardonnet Laurent	PRLD	Common Stock	P - Purchase	D		4.2300	10,000	42		24,500
2022-05-04	2022-05-02	4	Huang Jane	PRLD	Restricted Stock Unit	A - Award	D			150,000		150,000
2022-05-04	2022-05-02	4	Huang Jane	PRLD	Employee Stock Option (Right to Buy)	A - Award	D	4.86		460,000		460,000
2022-04-04	2022-04-01	4	Combs Andrew	PRLD	Employee Stock Option (right to buy)	M - Exercise	D	1.89		-36,062		50,397
2022-04-04	2022-03-31	4	Combs Andrew	PRLD	Common Stock	M - Exercise	D		1.8900	36,062	68		304,442
2022-03-22	2022-03-21	4	Chardonnet Laurent	PRLD	Common Stock	A - Award	D		7.5100	6,500	49		14,500
2022-02-17	2022-02-15	4	Chardonnet Laurent	PRLD	Employee Stock Option (right to buy)	A - Award	D	10.58		90,000		90,000
2022-02-17	2022-02-15	4	Scherle Peggy	PRLD	Employee Stock Option (right to buy)	A - Award	D	10.58		100,000		100,000
2022-02-17	2022-02-15	4	Morosini Deborah	PRLD	Employee Stock Option (right to buy)	A - Award	D	10.58		90,000		90,000
2022-02-17	2022-02-15	4	Vaddi Krishna	PRLD	Employee Stock Option (right to buy)	A - Award	D	10.58		327,900		327,900
2022-02-17	2022-02-15	4	Combs Andrew	PRLD	Employee Stock Option (right to buy)	A - Award	D	10.58		100,000		100,000
2022-01-05	2022-01-03	4	Sandor Victor	PRLD	Director Stock Option (Right to Buy)	A - Award	D	13.22		11,206		11,206
2021-12-17	2021-12-15	4	Morosini Deborah	PRLD	Employee Stock Option (right to buy)	M - Exercise	D	12.85		-882		195,163
2021-12-17	2021-12-15	4	Morosini Deborah	PRLD	Employee Stock Option (right to buy)	M - Exercise	D	12.85		-24,853		74,575
2021-12-17	2021-12-15	4	Morosini Deborah	PRLD	Employee Stock Option (right to buy)	M - Exercise	D	1.89		-3,016		1,307
2021-12-17	2021-12-15	4	Morosini Deborah	PRLD	Common Stock	S - Sale	D		13.0000	-28,751	-374		444
2021-12-17	2021-12-15	4	Morosini Deborah	PRLD	Common Stock	M - Exercise	D		12.8500	25,735	331		29,195
2021-12-17	2021-12-15	4	Morosini Deborah	PRLD	Common Stock	M - Exercise	D		1.8900	3,016	6		3,460
2021-12-15	2021-12-14	4	Combs Andrew	PRLD	Common Stock	P - Purchase	D		11.6000	4,000	46		268,380
2021-12-15	2021-12-13	4	Combs Andrew	PRLD	Common Stock	P - Purchase	D		12.1200	4,000	48		264,380
2021-12-14	2021-12-13	4	Chardonnet Laurent	PRLD	Common Stock	A - Award	D		12.2800	5,000	61		8,000
2021-12-14	2021-12-13	4	Vaddi Krishna	PRLD	Common Stock	A - Award	D		12.1294	8,000	97		1,053,519
2021-12-01	2021-11-29	4	Chardonnet Laurent	PRLD	Employee Stock Option (Right to Buy)	A - Award	D	13.75		180,000		180,000
2021-12-01		3	Chardonnet Laurent	PRLD	Common Stock		D						3,000
2021-11-18	2021-11-16	4	Morosini Deborah	PRLD	Employee Stock Option (right to buy)	M - Exercise	D	12.85		-28,751		196,045
2021-11-18	2021-11-16	4	Morosini Deborah	PRLD	Common Stock	S - Sale	D		16.4250	-400	-7		444
2021-11-18	2021-11-16	4	Morosini Deborah	PRLD	Common Stock	S - Sale	D		15.8711	-28,351	-450		844
2021-11-18	2021-11-16	4	Morosini Deborah	PRLD	Common Stock	M - Exercise	D		12.8500	28,751	369		29,195
2021-10-14	2021-10-13	4	Sandor Victor	PRLD	Director Stock Option (Right to Buy)	A - Award	D	15.81		8,022		8,022
2021-10-06	2021-10-05	4	Mauro David J	PRLD	Employee Stock Option (Right to Buy)	M - Exercise	D	1.89		-15,000		137,610
2021-10-06	2021-10-05	4	Mauro David J	PRLD	Common Stock	S - Sale	D		32.0637	-1,289	-41		0
2021-10-06	2021-10-05	4	Mauro David J	PRLD	Common Stock	S - Sale	D		31.3030	-7,803	-244		1,289
2021-10-06	2021-10-05	4	Mauro David J	PRLD	Common Stock	S - Sale	D		30.2577	-5,908	-179		9,092
2021-10-06	2021-10-05	4	Mauro David J	PRLD	Common Stock	M - Exercise	D		1.8900	15,000	28		15,000
2021-09-09	2021-09-07	4	Mauro David J	PRLD	Employee Stock Option (Right to Buy)	M - Exercise	D	1.89		-15,000		167,610
2021-09-09	2021-09-07	4	Mauro David J	PRLD	Common Stock	S - Sale	D		37.7876	-4,640	-175		0
2021-09-09	2021-09-07	4	Mauro David J	PRLD	Common Stock	S - Sale	D		36.9234	-2,873	-106		4,640
2021-09-09	2021-09-07	4	Mauro David J	PRLD	Common Stock	S - Sale	D		35.9112	-7,487	-269		7,513
2021-09-09	2021-09-07	4	Mauro David J	PRLD	Common Stock	M - Exercise	D		1.8900	15,000	28		15,000
2021-09-07	2021-09-02	4	Pierce Christopher	PRLD	Employee Stock Option (right to buy)	M - Exercise	D	12.85		-17,000		207,796
2021-09-07	2021-09-02	4	Pierce Christopher	PRLD	Common Stock	S - Sale	D		42.4974	-6,930	-295		3,750
2021-09-07	2021-09-02	4	Pierce Christopher	PRLD	Common Stock	S - Sale	D		41.5176	-6,727	-279		10,680
2021-09-07	2021-09-02	4	Pierce Christopher	PRLD	Common Stock	S - Sale	D		40.2922	-3,343	-135		17,407
2021-09-07	2021-09-02	4	Pierce Christopher	PRLD	Common Stock	M - Exercise	D		12.8500	17,000	218		20,750
2021-08-30	2021-08-27	4	Scherle Peggy	PRLD	Employee Stock Option (Right to Buy)	M - Exercise	D	1.43		-6,014		27,018
2021-08-30	2021-08-27	4	Scherle Peggy	PRLD	Common Stock	S - Sale	D		37.0761	-607	-23		172,920
2021-08-30	2021-08-27	4	Scherle Peggy	PRLD	Common Stock	S - Sale	D		36.2340	-2,707	-98		173,527
2021-08-30	2021-08-27	4	Scherle Peggy	PRLD	Common Stock	S - Sale	D		35.3247	-2,700	-95		176,234
2021-08-30	2021-08-27	4	Scherle Peggy	PRLD	Common Stock	M - Exercise	D		1.4300	6,014	9		178,934
2021-08-30	2021-08-26	4	Scherle Peggy	PRLD	Employee Stock Option (Right to Buy)	M - Exercise	D	1.43		-1,700		33,032
2021-08-30	2021-08-26	4	Scherle Peggy	PRLD	Common Stock	S - Sale	D		35.1879	-1,700	-60		172,920
2021-08-30	2021-08-26	4	Scherle Peggy	PRLD	Common Stock	M - Exercise	D		1.4300	1,700	2		174,620
2021-08-27	2021-08-25	4	Piper Brian	PRLD	Employee Stock Option (Right to Buy)	M - Exercise	D	1.89		-8,333		264,329
2021-08-27	2021-08-25	4	Piper Brian	PRLD	Common Stock	S - Sale	D		34.3299	-2,344	-80		0
2021-08-27	2021-08-25	4	Piper Brian	PRLD	Common Stock	S - Sale	D		33.2308	-3,889	-129		2,344
2021-08-27	2021-08-25	4	Piper Brian	PRLD	Common Stock	S - Sale	D		32.4398	-2,100	-68		6,233
2021-08-27	2021-08-25	4	Piper Brian	PRLD	Common Stock	M - Exercise	D		1.8900	8,333	16		8,333
2021-08-17	2021-08-13	4	Scherle Peggy	PRLD	Employee Stock Option (Right to Buy)	M - Exercise	D	1.43		-1,728		34,732
2021-08-17	2021-08-13	4	Scherle Peggy	PRLD	Employee Stock Option (Right to Buy)	M - Exercise	D	1.89		-558		42,672
2021-08-17	2021-08-13	4	Scherle Peggy	PRLD	Common Stock	S - Sale	D		35.0662	-2,286	-80		172,920
2021-08-17	2021-08-13	4	Scherle Peggy	PRLD	Common Stock	M - Exercise	D		1.4300	1,728	2		175,206
2021-08-17	2021-08-13	4	Scherle Peggy	PRLD	Common Stock	M - Exercise	D		1.8900	558	1		173,478
2021-08-09	2021-08-05	4	Mauro David J	PRLD	Employee Stock Option (Right to Buy)	M - Exercise	D	1.89		-15,000		167,610
2021-08-09	2021-08-05	4	Mauro David J	PRLD	Common Stock	S - Sale	D		32.6300	-100	-3		0
2021-08-09	2021-08-05	4	Mauro David J	PRLD	Common Stock	S - Sale	D		32.1457	-6,721	-216		100
2021-08-09	2021-08-05	4	Mauro David J	PRLD	Common Stock	S - Sale	D		31.0278	-2,063	-64		6,821
2021-08-09	2021-08-05	4	Mauro David J	PRLD	Common Stock	S - Sale	D		29.9329	-6,116	-183		8,884
2021-08-09	2021-08-05	4	Mauro David J	PRLD	Common Stock	M - Exercise	D		1.8900	15,000	28		15,000
2021-07-29	2021-07-27	4	Scherle Peggy	PRLD	Employee Stock Option (Right to Buy)	M - Exercise	D	1.43		-20,000		36,460
2021-07-29	2021-07-27	4	Scherle Peggy	PRLD	Common Stock	S - Sale	D		36.0882	-680	-25		172,920
2021-07-29	2021-07-27	4	Scherle Peggy	PRLD	Common Stock	S - Sale	D		35.4472	-19,320	-685		173,600
2021-07-29	2021-07-27	4	Scherle Peggy	PRLD	Common Stock	M - Exercise	D		1.4300	20,000	29		192,920
2021-07-22	2021-07-20	4	Scherle Peggy	PRLD	Employee Stock Option (Right to Buy)	A - Award	D	31.23		95,000		95,000
2021-07-22	2021-07-20	4	Vaddi Krishna	PRLD	Employee Stock Option (Right to Buy)	A - Award	D	31.23		285,800		285,800
2021-07-22	2021-07-20	4	Morosini Deborah	PRLD	Employee Stock Option (Right to Buy)	A - Award	D	31.23		85,000		85,000
2021-07-22	2021-07-20	4	Mauro David J	PRLD	Employee Stock Option (Right to Buy)	A - Award	D	31.23		95,000		95,000
2021-07-22	2021-07-20	4	Pierce Christopher	PRLD	Employee Stock Option (Right to Buy)	A - Award	D	31.23		85,000		85,000
2021-07-22	2021-07-20	4	Piper Brian	PRLD	Employee Stock Option (Right to Buy)	A - Award	D	31.23		115,650		115,650
2021-07-22	2021-07-20	4	Combs Andrew	PRLD	Employee Stock Option (Right to Buy)	A - Award	D	31.23		95,000		95,000
2021-07-20	2021-07-19	4	Babler Martin	PRLD	Employee Stock Option (Right to Buy)	A - Award	D	31.37		36,400		36,400
2021-07-08	2021-07-06	4	Mauro David J	PRLD	Employee Stock Option (Right to Buy)	M - Exercise	D	1.89		-15,000		182,610
2021-07-08	2021-07-06	4	Mauro David J	PRLD	Common Stock	S - Sale	D		28.8433	-300	-9		0
2021-07-08	2021-07-06	4	Mauro David J	PRLD	Common Stock	S - Sale	D		28.1343	-4,255	-120		300
2021-07-08	2021-07-06	4	Mauro David J	PRLD	Common Stock	S - Sale	D		27.1654	-10,445	-284		4,555
2021-07-08	2021-07-06	4	Mauro David J	PRLD	Common Stock	M - Exercise	D		1.8900	15,000	28		15,000
2021-06-22	2021-06-18	4	Sandor Victor	PRLD	Director Stock Option (Right to Buy)	A - Award	D	31.02		23,344		23,344
2021-06-22	2021-06-18	4	FRIEDMAN PAUL A	PRLD	Director Stock Option (Right to Buy)	A - Award	D	31.02		23,344		23,344
2021-06-22	2021-06-18	4	Dier Mardi	PRLD	Director Stock Option (Right to Buy)	A - Award	D	31.02		23,344		23,344
2021-06-22	2021-06-18	4	Bonita David P	PRLD	Director Stock Option (Right to Buy)	A - Award	D	31.02		23,344		23,344
2021-06-22	2021-06-18	4	BAKER BROS. ADVISORS LP See Footnotes	PRLD	Non-Qualified Stock Options (right to buy)	A - Award	I	31.02		23,344		23,344
2021-06-09	2021-06-07	4	Mauro David J	PRLD	Common Stock	M - Exercise	D	1.89		-15,000		197,610
2021-06-09	2021-06-07	4	Mauro David J	PRLD	Common Stock	S - Sale	D		32.7295	-12,700	-416		0
2021-06-09	2021-06-07	4	Mauro David J	PRLD	Common Stock	S - Sale	D		31.6244	-900	-28		12,700
2021-06-09	2021-06-07	4	Mauro David J	PRLD	Common Stock	S - Sale	D		30.3541	-1,400	-42		13,600
2021-06-09	2021-06-07	4	Mauro David J	PRLD	Common Stock	M - Exercise	D		1.8900	15,000	28		15,000
2021-05-27	2021-05-25	4	Piper Brian	PRLD	Employee Stock Option (Right to Buy)	M - Exercise	D	1.89		-8,333		272,662
2021-05-27	2021-05-25	4	Piper Brian	PRLD	Common Stock	S - Sale	D		36.0930	-399	-14		0
2021-05-27	2021-05-25	4	Piper Brian	PRLD	Common Stock	S - Sale	D		35.4469	-1,736	-62		399
2021-05-27	2021-05-25	4	Piper Brian	PRLD	Common Stock	S - Sale	D		34.1119	-3,088	-105		2,135
2021-05-27	2021-05-25	4	Piper Brian	PRLD	Common Stock	S - Sale	D		33.5250	-3,110	-104		5,223
2021-05-27	2021-05-25	4	Piper Brian	PRLD	Common Stock	M - Exercise	D		1.8900	8,333	16		8,333
2021-05-11	2021-05-07	4	Scherle Peggy	PRLD	Employee Stock Option (right to buy)	M - Exercise	D	1.43		-10,000		56,460
2021-05-11	2021-05-07	4	Scherle Peggy	PRLD	Common Stock	S - Sale	D		41.8500	-200	-8		172,920
2021-05-11	2021-05-07	4	Scherle Peggy	PRLD	Common Stock	S - Sale	D		41.1395	-5,836	-240		173,120
2021-05-11	2021-05-07	4	Scherle Peggy	PRLD	Common Stock	S - Sale	D		40.2957	-3,964	-160		178,956
2021-05-11	2021-05-07	4	Scherle Peggy	PRLD	Common Stock	M - Exercise	D		1.4300	10,000	14		182,920
2021-05-10	2021-05-05	4	Mauro David J	PRLD	Common Stock	M - Exercise	D	1.89		-15,000		212,610
2021-05-10	2021-05-05	4	Mauro David J	PRLD	Common Stock	S - Sale	D		41.0682	-1,109	-46		0
2021-05-10	2021-05-05	4	Mauro David J	PRLD	Common Stock	S - Sale	D		40.2967	-10,476	-422		1,109
2021-05-10	2021-05-05	4	Mauro David J	PRLD	Common Stock	S - Sale	D		39.3555	-3,415	-134		11,585
2021-05-10	2021-05-05	4	Mauro David J	PRLD	Common Stock	M - Exercise	D		1.8900	15,000	28		15,000
2021-04-30	2021-04-29	4	Pierce Christopher	PRLD	Employee Stock Option (right to buy)	M - Exercise	D	1.89		-3,295		4,323
2021-04-30	2021-04-29	4	Pierce Christopher	PRLD	Common Stock	S - Sale	D		40.2928	-3,295	-133		3,750
2021-04-30	2021-04-29	4	Pierce Christopher	PRLD	Common Stock	M - Exercise	D		1.8900	3,295	6		7,045
2021-04-30	2021-04-29	4	Morosini Deborah	PRLD	Employee Stock Option (right to buy)	M - Exercise	D	1.89		-3,223		4,323
2021-04-30	2021-04-29	4	Morosini Deborah	PRLD	Common Stock	S - Sale	D		40.2896	-3,223	-130		444
2021-04-30	2021-04-29	4	Morosini Deborah	PRLD	Common Stock	M - Exercise	D		1.8900	3,223	6		3,667
2021-04-29	2021-04-27	4	Mauro David J	PRLD	Employee Stock Option (right to buy)	M - Exercise	D	1.89		-25,000		227,610
2021-04-29	2021-04-27	4	Mauro David J	PRLD	Common Stock	S - Sale	D		36.1137	-1,711	-62		0
2021-04-29	2021-04-27	4	Mauro David J	PRLD	Common Stock	S - Sale	D		35.6759	-15,601	-557		1,711
2021-04-29	2021-04-27	4	Mauro David J	PRLD	Common Stock	S - Sale	D		34.6615	-7,688	-266		17,312
2021-04-29	2021-04-27	4	Mauro David J	PRLD	Common Stock	M - Exercise	D		1.8900	25,000	47		25,000
2021-04-21	2021-04-19	4	Mauro David J	PRLD	Employee Stock Option (right to buy)	M - Exercise	D	1.89		-25,000		252,610
2021-04-21	2021-04-19	4	Mauro David J	PRLD	Common Stock	S - Sale	D		31.2692	-4,000	-125		0
2021-04-21	2021-04-19	4	Mauro David J	PRLD	Common Stock	S - Sale	D		30.8225	-21,000	-647		4,000
2021-04-21	2021-04-19	4	Mauro David J	PRLD	Common Stock	M - Exercise	D		1.8900	25,000	47		25,000
2021-04-15	2021-04-08	4	Scherle Peggy	PRLD	Employee Stock Option (right to buy)	M - Exercise	D	1.43		-4,630		66,460
2021-04-15	2021-04-08	4	Scherle Peggy	PRLD	Common Stock	S - Sale	D		39.5688	-1,669	-66		172,920
2021-04-15	2021-04-08	4	Scherle Peggy	PRLD	Common Stock	S - Sale	D		38.9726	-669	-26		174,589
2021-04-15	2021-04-08	4	Scherle Peggy	PRLD	Common Stock	S - Sale	D		37.7182	-875	-33		175,258
2021-04-15	2021-04-08	4	Scherle Peggy	PRLD	Common Stock	S - Sale	D		36.9707	-1,417	-52		176,133
2021-04-15	2021-04-08	4	Scherle Peggy	PRLD	Common Stock	A - Award	D		1.4300	4,630	7		177,550
2021-04-15	2021-04-08	4	Pierce Christopher	PRLD	Employee Stock Option (right to buy)	M - Exercise	D	1.89		-200		7,618
2021-04-15	2021-04-08	4	Pierce Christopher	PRLD	Common Stock	S - Sale	D		40.0000	-200	-8		3,750
2021-04-15	2021-04-08	4	Pierce Christopher	PRLD	Common Stock	A - Award	D		1.8900	200	0		3,950
2021-04-15	2021-04-08	4	Morosini Deborah	PRLD	Employee Stock Option (right to buy)	M - Exercise	D	1.89		-100		7,546
2021-04-15	2021-04-08	4	Morosini Deborah	PRLD	Common Stock	S - Sale	D		40.0000	-100	-4		444
2021-04-15	2021-04-08	4	Morosini Deborah	PRLD	Common Stock	M - Exercise	D		1.8900	100	0		544
2021-04-15	2021-04-08	4	Mauro David J	PRLD	Employee Stock Option (right to buy)	M - Exercise	D	1.89		-9,617		277,610
2021-04-15	2021-04-08	4	Mauro David J	PRLD	Common Stock	S - Sale	D		39.5584	-3,549	-140		0
2021-04-15	2021-04-08	4	Mauro David J	PRLD	Common Stock	S - Sale	D		38.9972	-1,293	-50		3,549
2021-04-15	2021-04-08	4	Mauro David J	PRLD	Common Stock	S - Sale	D		37.8283	-1,501	-57		4,842
2021-04-15	2021-04-08	4	Mauro David J	PRLD	Common Stock	S - Sale	D		37.0360	-3,274	-121		6,343
2021-04-15	2021-04-08	4	Mauro David J	PRLD	Common Stock	M - Exercise	D		1.8900	9,617	18		9,617
2021-04-09	2021-04-07	4	Scherle Peggy	PRLD	Employee Stock Option (right to buy)	M - Exercise	D	1.43		-15,370		71,090
2021-04-09	2021-04-07	4	Scherle Peggy	PRLD	Common Stock	S - Sale	D		40.3000	-200	-8		172,920
2021-04-09	2021-04-07	4	Scherle Peggy	PRLD	Common Stock	S - Sale	D		39.6278	-6,881	-273		173,120
2021-04-09	2021-04-07	4	Scherle Peggy	PRLD	Common Stock	S - Sale	D		39.0162	-8,289	-323		180,001
2021-04-09	2021-04-07	4	Scherle Peggy	PRLD	Common Stock	A - Award	D		1.4300	15,370	22		188,290
2021-04-09	2021-04-07	4	Pierce Christopher	PRLD	Employee Stock Option (right to buy)	M - Exercise	D	1.89		-828		7,818
2021-04-09	2021-04-07	4	Pierce Christopher	PRLD	Common Stock	S - Sale	D		40.0826	-828	-33		3,750
2021-04-09	2021-04-07	4	Pierce Christopher	PRLD	Common Stock	A - Award	D		1.8900	828	2		4,578
2021-04-09	2021-04-07	4	Morosini Deborah	PRLD	Employee Stock Option (right to buy)	M - Exercise	D	1.89		-1,000		7,646
2021-04-09	2021-04-07	4	Morosini Deborah	PRLD	Common Stock	S - Sale	D		40.0430	-1,000	-40		444
2021-04-09	2021-04-07	4	Morosini Deborah	PRLD	Common Stock	M - Exercise	D		1.8900	1,000	2		1,444
2021-04-09	2021-04-07	4	Mauro David J	PRLD	Employee Stock Option (right to buy)	M - Exercise	D	1.89		-15,383		287,227
2021-04-09	2021-04-07	4	Mauro David J	PRLD	Common Stock	S - Sale	D		39.6888	-7,083	-281		0
2021-04-09	2021-04-07	4	Mauro David J	PRLD	Common Stock	S - Sale	D		39.0250	-8,300	-324		7,083
2021-04-09	2021-04-07	4	Mauro David J	PRLD	Common Stock	M - Exercise	D		1.8900	15,383	29		15,383
2021-01-29	2021-01-27	4	BAKER BROS. ADVISORS LP See Footnotes	PRLD	Non-Qualified Stock Options (right to buy)	M - Exercise	I	12.85		-5,188		41,500
2021-01-29	2021-01-27	4	BAKER BROS. ADVISORS LP See Footnotes	PRLD	Non-Qualified Stock Options (right to buy)	M - Exercise	I	12.85		-5,188		41,500
2021-01-29	2021-01-27	4	BAKER BROS. ADVISORS LP See Footnotes	PRLD	Common Stock	M - Exercise	I		12.8500	5,188	67		9,252,951
2021-01-29	2021-01-27	4	BAKER BROS. ADVISORS LP See Footnotes	PRLD	Common Stock	M - Exercise	I		12.8500	5,188	67		9,252,951
2021-01-13	2021-01-11	4	BAKER BROS. ADVISORS LP See Footnotes	PRLD	Non-Voting Common Stock	P - Purchase	I		60.0000	154,222	9,253	5,212,371
2021-01-13	2021-01-11	4	BAKER BROS. ADVISORS LP See Footnotes	PRLD	Non-Voting Common Stock	P - Purchase	I		60.0000	12,444	747	509,480
2021-01-12	2021-01-11	4	ORBIMED ADVISORS LLC See Footnotes	PRLD	Non-Voting Common Stock	P - Purchase	I		60.0000	41,700	2,502	5,596,886
2021-01-12	2021-01-11	4	Bonita David P See Footnotes	PRLD	Non-Voting Common Stock	P - Purchase	I		60.0000	41,700	2,502	5,596,886
2020-09-30	2020-08-21	4/A	ORBIMED ADVISORS LLC	PRLD	Series C Preferred Stock	P - Purchase	I			1,033,084		1,033,084
2020-09-30	2020-03-27	4/A	ORBIMED ADVISORS LLC	PRLD	Series B Preferred Stock	P - Purchase	I			3,681,822		7,363,644
2020-09-30	2020-09-29	4	FRIEDMAN PAUL A	PRLD	Series B Preferred Stock	C - Conversion	D			-152,576		0
2020-09-30	2020-09-29	4	FRIEDMAN PAUL A	PRLD	Series A Preferred Stock	C - Conversion	D			-295,794		0
2020-09-30	2020-09-29	4	FRIEDMAN PAUL A	PRLD	Common Stock	C - Conversion	D			152,576			500,098
2020-09-30	2020-09-29	4	FRIEDMAN PAUL A	PRLD	Common Stock	C - Conversion	D			295,794			347,522
2020-09-30	2020-03-27	4	FRIEDMAN PAUL A	PRLD	Series B Preferred Stock	P - Purchase	D			76,288		152,576
2020-09-30	2020-09-29	4	Bonita David P	PRLD	Non-Voting Common Stock	C - Conversion	I			5,555,186		5,555,186
2020-09-30	2020-09-29	4	Bonita David P	PRLD	Series C Preferred Stock	C - Conversion	I			-413,234		0
2020-09-30	2020-09-29	4	Bonita David P	PRLD	Series C Preferred Stock	C - Conversion	I			-619,850		0
2020-09-30	2020-09-29	4	Bonita David P	PRLD	Series B Preferred Stock	C - Conversion	I			-2,945,458		0
2020-09-30	2020-09-29	4	Bonita David P	PRLD	Series B Preferred Stock	C - Conversion	I			-4,418,186		0
2020-09-30	2020-09-29	4	Bonita David P	PRLD	Series A Preferred Stock	C - Conversion	I			-2,196,494		0
2020-09-30	2020-09-29	4	Bonita David P	PRLD	Series A Preferred Stock	C - Conversion	I			-3,294,743		0
2020-09-30	2020-09-29	4	Bonita David P	PRLD	Common Stock	C - Conversion	I			8,332,779			9,250,191
2020-09-30	2020-09-25	4	Bonita David P	PRLD	Common Stock	P - Purchase	I		19.0000	710,500	13,500		917,412
2020-09-30	2020-09-25	4	Bonita David P	PRLD	Common Stock	P - Purchase	I		19.0000	526,300	10,000		526,300
2020-09-30	2020-09-24	4	Bonita David P	PRLD	Director Stock Option (right to buy)	A - Award	D	12.85		46,688		46,688
2020-09-30	2020-08-21	4	Bonita David P	PRLD	Series C Preferred Stock	P - Purchase	I			1,033,084		1,033,084
2020-09-30	2020-03-27	4	Bonita David P	PRLD	Series B Preferred Stock	P - Purchase	I			3,681,822		7,363,644
2020-09-30	2020-09-29	4	BAKER BROS. ADVISORS LP See Footnotes	PRLD	Non-Voting Common Stock	C - Conversion	I			382,884		5,058,149
2020-09-30	2020-09-29	4	BAKER BROS. ADVISORS LP See Footnotes	PRLD	Series C Convertible Preferred Stock	C - Conversion	I			-382,884		0
2020-09-30	2020-09-29	4	BAKER BROS. ADVISORS LP See Footnotes	PRLD	Non-Voting Common Stock	C - Conversion	I			30,349		497,036
2020-09-30	2020-09-29	4	BAKER BROS. ADVISORS LP See Footnotes	PRLD	Series C Convertible Preferred Stock	C - Conversion	I			-30,349		0
2020-09-30	2020-09-29	4	BAKER BROS. ADVISORS LP See Footnotes	PRLD	Series C Convertible Preferred Stock	C - Conversion	I			-574,327		0
2020-09-30	2020-09-29	4	BAKER BROS. ADVISORS LP See Footnotes	PRLD	Series C Convertible Preferred Stock	C - Conversion	I			-45,524		0
2020-09-30	2020-09-29	4	BAKER BROS. ADVISORS LP See Footnotes	PRLD	Non-Voting Common Stock	C - Conversion	I			2,698,424		4,675,265
2020-09-30	2020-09-29	4	BAKER BROS. ADVISORS LP See Footnotes	PRLD	Series B Convertible Preferred Stock	C - Conversion	I			-2,698,424		0
2020-09-30	2020-09-29	4	BAKER BROS. ADVISORS LP See Footnotes	PRLD	Non-Voting Common Stock	C - Conversion	I			247,034		466,687
2020-09-30	2020-09-29	4	BAKER BROS. ADVISORS LP See Footnotes	PRLD	Series B Convertible Preferred Stock	C - Conversion	I			-247,034		0
2020-09-30	2020-09-29	4	BAKER BROS. ADVISORS LP See Footnotes	PRLD	Series B Convertible Preferred Stock	C - Conversion	I			-4,047,634		0
2020-09-30	2020-09-29	4	BAKER BROS. ADVISORS LP See Footnotes	PRLD	Series B Convertible Preferred Stock	C - Conversion	I			-370,552		0
2020-09-30	2020-09-29	4	BAKER BROS. ADVISORS LP See Footnotes	PRLD	Non-Voting Common Stock	C - Conversion	I			1,976,841		1,976,841
2020-09-30	2020-09-29	4	BAKER BROS. ADVISORS LP See Footnotes	PRLD	Series A Convertible Preferred Stock	C - Conversion	I			-1,976,841		0
2020-09-30	2020-09-29	4	BAKER BROS. ADVISORS LP See Footnotes	PRLD	Non-Voting Common Stock	C - Conversion	I			219,653		219,653
2020-09-30	2020-09-29	4	BAKER BROS. ADVISORS LP See Footnotes	PRLD	Series A Convertible Preferred Stock	C - Conversion	I			-219,653		0
2020-09-30	2020-09-29	4	BAKER BROS. ADVISORS LP See Footnotes	PRLD	Series A Convertible Preferred Stock	C - Conversion	I			-2,965,263		0
2020-09-30	2020-09-29	4	BAKER BROS. ADVISORS LP See Footnotes	PRLD	Series A Convertible Preferred Stock	C - Conversion	I			-329,478		0
2020-09-30	2020-09-29	4	BAKER BROS. ADVISORS LP See Footnotes	PRLD	Common Stock	P - Purchase	I		19.0000	1,474,319	28,012		9,247,763
2020-09-30	2020-09-29	4	BAKER BROS. ADVISORS LP See Footnotes	PRLD	Common Stock	P - Purchase	I		19.0000	104,628	1,988		870,873
2020-09-30	2020-09-29	4	BAKER BROS. ADVISORS LP See Footnotes	PRLD	Common Stock	C - Conversion	I			574,327			7,773,444
2020-09-30	2020-09-29	4	BAKER BROS. ADVISORS LP See Footnotes	PRLD	Common Stock	C - Conversion	I			45,524			766,245
2020-09-30	2020-09-29	4	BAKER BROS. ADVISORS LP See Footnotes	PRLD	Common Stock	C - Conversion	I			4,047,634			7,199,117
2020-09-30	2020-09-29	4	BAKER BROS. ADVISORS LP See Footnotes	PRLD	Common Stock	C - Conversion	I			370,552			720,721
2020-09-30	2020-09-29	4	BAKER BROS. ADVISORS LP See Footnotes	PRLD	Common Stock	C - Conversion	I			2,965,263			3,151,483
2020-09-30	2020-09-29	4	BAKER BROS. ADVISORS LP See Footnotes	PRLD	Common Stock	C - Conversion	I			329,478			350,169
2020-09-30	2020-09-24	4	BAKER BROS. ADVISORS LP See Footnotes	PRLD	Non-Qualified Stock Option (right to buy)	A - Award	I	12.85		46,688		46,688
2020-09-30	2020-08-21	4	BAKER BROS. ADVISORS LP See Footnotes	PRLD	Series C Preferred Stock	P - Purchase	I		14.5196	957,211	13,898	957,211
2020-09-30	2020-08-21	4	BAKER BROS. ADVISORS LP See Footnotes	PRLD	Series C Preferred Stock	P - Purchase	I		14.5196	75,873	1,102	75,873
2020-09-30	2020-03-27	4	BAKER BROS. ADVISORS LP See Footnotes	PRLD	Series B Preferred Stock	P - Purchase	I		3.9324	3,373,029	13,264	3,373,029
2020-09-30	2020-03-27	4	BAKER BROS. ADVISORS LP See Footnotes	PRLD	Series B Preferred Stock	P - Purchase	I		3.9324	308,793	1,214	308,793
2020-09-29	2020-09-29	4	Combs Andrew	PRLD	Common Stock	P - Purchase	D		19.0000	1,000	19		260,380
2020-09-29	2020-09-29	4	Vaddi Krishna By Trust	PRLD	Series A Preferred Stock	C - Conversion	I			-32,876		0
2020-09-29	2020-09-29	4	Vaddi Krishna By Trust	PRLD	Series A Preferred Stock	C - Conversion	I			-32,876		0
2020-09-29	2020-09-29	4	Vaddi Krishna	PRLD	Series A Preferred Stock	C - Conversion	I			-101,477		0
2020-09-29	2020-09-29	4	Vaddi Krishna By Trust	PRLD	Common Stock	C - Conversion	I			32,876			551,774
2020-09-29	2020-09-29	4	Vaddi Krishna By Trust	PRLD	Common Stock	C - Conversion	I			32,876			551,774
2020-09-29	2020-09-29	4	Vaddi Krishna	PRLD	Common Stock	C - Conversion	I			101,477			101,477
2020-09-29	2020-09-29	4	Pierce Christopher	PRLD	Common Stock	P - Purchase	D		19.0000	3,750	71		3,750
2020-09-29	2020-09-29	4	Morosini Deborah	PRLD	Common Stock	P - Purchase	D		19.0000	444	8		444
2020-09-29	2020-09-29	4	Dier Mardi	PRLD	Common Stock	P - Purchase	D		19.0000	10,000	190		10,000
2020-09-29	2020-09-29	4	ORBIMED ADVISORS LLC	PRLD	Non-Voting Common Stock	C - Conversion	I			5,555,186		5,555,186
2020-09-29	2020-09-29	4	ORBIMED ADVISORS LLC	PRLD	Series C Preferred Stock	C - Conversion	I			-413,234		0
2020-09-29	2020-09-29	4	ORBIMED ADVISORS LLC	PRLD	Series C Preferred Stock	C - Conversion	I			-619,850		0
2020-09-29	2020-09-29	4	ORBIMED ADVISORS LLC	PRLD	Series B Preferred Stock	C - Conversion	I			-2,945,458		0
2020-09-29	2020-09-29	4	ORBIMED ADVISORS LLC	PRLD	Series B Preferred Stock	C - Conversion	I			-4,418,186		0
2020-09-29	2020-09-29	4	ORBIMED ADVISORS LLC	PRLD	Series A Prefered Stock	C - Conversion	I			-2,196,494		0
2020-09-29	2020-09-29	4	ORBIMED ADVISORS LLC	PRLD	Series A Preferred Stock	C - Conversion	I			-3,294,743		0
2020-09-29	2020-09-29	4	ORBIMED ADVISORS LLC	PRLD	Common Stock	C - Conversion	I			8,332,779			9,250,191
2020-09-29	2020-09-25	4	ORBIMED ADVISORS LLC	PRLD	Common Stock	P - Purchase	I		19.0000	710,500	13,500		917,412
2020-09-29	2020-09-25	4	ORBIMED ADVISORS LLC	PRLD	Common Stock	P - Purchase	I		19.0000	526,300	10,000		526,300
2020-09-28	2020-09-24	4	Sandor Victor	PRLD	Director Stock Option (right to buy)	A - Award	D	19.00		3,458		3,458
2020-09-28	2020-09-24	4	Dier Mardi	PRLD	Director Stock Option (right to buy)	A - Award	D	19.00		3,458		3,458
2020-09-24		3	Scherle Peggy	PRLD	Common Stock		D						172,920
2020-09-24		3	BAKER JULIAN	PRLD	Common Stock		I						186,220
2020-09-24		3	BAKER JULIAN	PRLD	Common Stock		I						20,691
2020-09-24		3	Vaddi Krishna By Trust	PRLD	Common Stock		I						423,655
2020-09-24		3	Vaddi Krishna	PRLD	Common Stock		D						1,045,519
2020-09-24		3	Vaddi Krishna By Trust	PRLD	Common Stock		I						518,898
2020-09-24		3	Vaddi Krishna By Trust	PRLD	Common Stock		I						518,900
2020-09-24		3	OrbiMed Capital GP VI LLC	PRLD	Common Stock		I						206,912
2020-09-24		3	FRIEDMAN PAUL A	PRLD	Common Stock		D						51,728
2020-09-24		3	Combs Andrew	PRLD	Common Stock		D						259,380
2020-09-24		3	Bonita David P See footnotes	PRLD	Common Stock		I						206,912

Pembelian sekuritas non-derivatif atau derivatif di pasar terbuka atau secara pribadi.

Penjualan terbuka atau penjualan pribadi atas sekuritas non-derivatif atau derivatif.

Hibah, penghargaan, atau perolehan sekuritas lainnya dari perusahaan (seperti opsi)

Konversi turunan

Penjualan atau pengalihan sekuritas kembali ke perusahaan.

Pembayaran harga pelaksanaan atau kewajiban pajak menggunakan sebagian sekuritas yang diterima dari perusahaan.

Pemberian sekuritas oleh atau kepada orang dalam.

Swap ekuitas dan transaksi lindung nilai serupa

Pelaksanaan atau konversi sekuritas derivatif yang diterima dari perusahaan (seperti opsi)

Transaksi yang dilaporkan secara sukarela pada Formulir 4.

Lainnya (disertai dengan catatan kaki yang menjelaskan transaksi tersebut)

PRLD / Prelude Therapeutics Incorporated - Insider Trading and Ownership Report - SEC Form 3, 4, 5