| Jumlah Saham Beredar | 126,289,910 shares |
| Saham Orang Dalam | 38,975,141 shares |
| Kepemilikan oleh Orang Dalam | 30.86 % |
| Orang Dalam Sejati | 38 |
Skor Sentimen Orang Dalam
Skor Sentimen Orang Dalam mengidentifikasi perusahaan yang dibeli oleh orang dalam korporat.
Ini adalah hasil dari model kuantitatif multifaktor yang canggih yang mengidentifikasi perusahaan dengan tingkat akumulasi internal tertinggi. Model penilaian ini menggunakan kombinasi dari jumlah bersih orang dalam yang membeli dalam 90 hari sebelumnya, total saham yang dibeli sebagai persentase dari jumlah saham yang beredar, dan total saham yang dimiliki oleh orang dalam. Angka tersebut berkisar dari 0 hingga 100, dengan angka yang lebih tinggi menunjukkan tingkat akumulasi yang lebih tinggi dibandingkan dengan perusahaan sejenis, dan 50 adalah rata-rata.
Frekuensi Pembaruan: Setiap Hari
Skor Sentimen Petugas
Skor Sentimen Pejabat menemukan perusahaan yang dibeli oleh Pejabat Korporat.
Menurut definisi, Pejabat Korporasi adalah Orang Dalam Korporasi, tetapi tidak seperti beberapa Orang Dalam lainnya (Pemegang Saham 10% dan Anggota Dewan), Pejabat bekerja untuk perusahaan setiap hari, dan mereka menggunakan uang mereka sendiri saat bertransaksi . (Pemegang Saham 10% dan Anggota Dewan seringkali adalah manajer dana yang mengelola uang orang lain.) Dengan demikian, transaksi orang dalam yang dilakukan oleh Pejabat jauh lebih signifikan dan harus ditangani dengan tepat.
Seperti Skor Sentimen Internal, Skor Sentimen Pejabat adalah hasil dari model kuantitatif multi-faktor yang canggih yang mengidentifikasi perusahaan dengan tingkat akumulasi pejabat tertinggi.
Frekuensi Pembaruan: Setiap Hari
Metrik Utama Orang Dalam
Kartu ini menunjukkan peringkat perusahaan berdasarkan berbagai metrik internal. Peringkat persentil menunjukkan bagaimana perusahaan ini dibandingkan dengan perusahaan lain di pasar AS. Peringkat yang lebih tinggi menunjukkan situasi yang lebih baik.
Sebagai contoh, secara umum diterima bahwa pembelian oleh orang dalam perusahaan adalah indikator positif, sehingga perusahaan dengan lebih banyak pembelian oleh orang dalam akan mendapat peringkat lebih tinggi daripada perusahaan dengan lebih sedikit pembelian oleh orang dalam (atau bahkan penjualan oleh orang dalam).
Jumlah Bersih Pembelian oleh Orang Dalam (Peringkat)
-3 ( )
10701 out of 11323Jumlah Bersih Pembelian oleh Orang Dalam adalah total jumlah orang dalam yang membeli dikurangi total jumlah orang dalam yang menjual dalam 90 hari terakhir. Peringkat persentil ditunjukkan di sini (kisaran dari 0 hingga 100%).
Persentase Saham yang Dibeli oleh Orang Dalam (Peringkat)
-0.510 %( )
10966 out of 11244Persentase Saham yang Dibeli oleh Orang Dalam adalah total jumlah saham yang dibeli oleh orang dalam dikurangi total jumlah saham yang dijual oleh orang dalam dalam 90 hari terakhir, dibagi dengan total jumlah saham yang beredar dan dikalikan dengan 100.
Grafik Perdagangan Orang Dalam
Grafik berikut menunjukkan Apellis Pharmaceuticals, Inc. transaksi orang dalam. Orang dalam adalah pejabat, direktur, atau investor signifikan dalam suatu perusahaan. Secara umum, melakukan transaksi di perusahaan mereka berdasarkan informasi material yang belum dipublikasikan adalah ilegal bagi orang dalam. Ini tidak berarti bahwa mereka dilarang melakukan transaksi apa pun di perusahaan mereka sendiri. Namun, mereka wajib melaporkan semua transaksi kepada SEC melalui Formulir 4.
Daftar Orang Dalam dan Metrik Profitabilitas
Tabel ini menampilkan daftar orang dalam yang diketahui, dan dibuat secara otomatis dari pengajuan yang diungkapkan kepada SEC. Selain nama, jabatan terbaru, dan sebutan direktur, pejabat, atau pemilik 10%, kami memberikan kepemilikan terbaru yang diungkapkan. Selain itu, jika memungkinkan, kami memberikan kinerja perdagangan historis untuk orang dalam tersebut. Kinerja perdagangan historis adalah rata-rata tertimbang dari kinerja transaksi pembelian pasar terbuka aktual yang dilakukan oleh orang dalam tersebut. Untuk informasi lebih lanjut tentang bagaimana ini dihitung, tonton webinar YouTube ini.
See our leaderboard of most profitable insider traders.
| Orang Dalam | Rata-rata Keuntungan (%) | Saham Dimiliki |
Terbagi Disesuaikan |
|---|---|---|---|
|
AJU IB Investment Co., Ltd.
10% Owner -
|
2,292,062 | 2,292,062 | |
| Steven Axon Chief Business Officer - [O] | 50,110 | 50,110 | |
| Caroline Baumal Chief Medical Officer - [O] | 93,301 | 93,301 | |
| Kelley Boucher Chief People Officer - [O] | 97,658 | 97,658 | |
| Brown Victoria L. Program Team Lead - [O] | 23,556 | 23,556 | |
| Lucia Celona See Remarks - [O] | 5,213 | 5,213 | |
| Gerald Chan Director - [D] | 17,705 | 17,705 | |
|
Bihua Chen
Director, 10% Owner -
[D]
|
3,473,925 | 3,473,925 | |
| James George Chopas VP/Chief Accounting Officer - [O] | 53,657 | 53,657 | |
|
Cormorant Asset Management, LLC
10% Owner -
|
3,473,925 | 3,473,925 | |
|
Cormorant Global Healthcare GP, LLC
10% Owner -
|
3,473,925 | 3,473,925 | |
|
Cormorant Global Healthcare Master Fund, LP
10% Owner -
|
3,473,925 | 3,473,925 |
| Orang Dalam | Rata-rata Keuntungan (%) | Saham Dimiliki |
Terbagi Disesuaikan |
|---|---|---|---|
| Mark Jeffrey DeLong Chief Business & Strat Officer - [O] | 83,945 | 83,945 | |
| Pascal Deschatelets Chief Scientific Officer - [O] | 1,160,496 | 1,160,496 | |
| Dunlop A. Sinclair Director - [D] | 158,393 | 158,393 | |
| Jeffrey Eisele Chief Development Officer - [O] | 55,312 | 55,312 | |
| Fonteyne Paul R. Director - [D] | 22,705 | 22,705 | |
| Cedric Francois Chief Executive Officer, Director - [D] [O] | 1,646,027 | 1,646,027 | |
|
Michael E Gellert
10% Owner -
|
943,989 | 943,989 | |
| Federico Grossi Chief Medical Officer - [O] | 94,884 | 94,884 | |
|
Hillhouse Capital Management, Ltd.
10% Owner -
|
3,527,152 | 3,527,152 | |
| Lackner Thomas A. See Remarks - [O] | 7,725 | 7,725 | |
| Karen Lewis Chief People Officer - [O] | 70,251 | 70,251 | |
| Leslie Meltzer Chief Research and Development - [O] | 61,804 | 61,804 | |
| Alec Machiels Director - [D] | 377,028 | 377,028 |
| Orang Dalam | Rata-rata Keuntungan (%) | Saham Dimiliki |
Terbagi Disesuaikan |
|---|---|---|---|
|
Morningside Venture Investments Ltd
10% Owner -
|
12,806,342 | 12,806,342 | |
| Nur Nicholson Chief Technical Officer - [O] | 83,664 | 83,664 | |
| Stephanie Monaghan O'Brien Director - [D] | 17,705 | 17,705 | |
| Nicole D Perry Vice President - Accounting - [O] | 4,847 | 4,847 | |
|
Potentia Holdings, LLC
10% Owner -
|
7,653,202 | 7,653,202 | |
| Lukas Scheibler Chief Research Officer - [O] | 68,299 | 68,299 | |
| Ahmad Sadr See Remarks - [O] | 2,725 | 2,725 | |
| Timothy Eugene Sullivan Chief Financial Officer - [O] | 128,665 | 128,665 | |
| Townsend Adam J. Chief Commercial Officer - [O] | 84,050 | 84,050 | |
| Craig A Wheeler Director - [D] | 16,483 | 16,483 | |
| Keli Walbert Director - [D] | 9,090 | 9,090 | |
| Watson David O. General Counsel - [O] | 203,866 | 203,866 | |
|
venBio Global Strategic Fund II L.P.
10% Owner -
|
3,579,305 | 3,579,305 |
Report errors via our new Insider Auditing Tool
Rekam Jejak Pembelian Orang Dalam - Analisis Keuntungan Jangka Pendek
Pada bagian ini, kami menganalisis profitabilitas setiap pembelian saham oleh orang dalam di pasar terbuka yang tidak direncanakan yang dilakukan di APLS / Apellis Pharmaceuticals, Inc.. Analisis ini membantu memahami apakah orang dalam tersebut secara konsisten menghasilkan pengembalian abnormal, dan layak untuk diikuti. Analisis ini dilakukan selama satu tahun setelah setiap transaksi, dan hasilnya bersifat teoretis .
Tabel berikut menunjukkan pembelian pasar terbuka terbaru yang bukan bagian dari rencana perdagangan otomatis.
Harga yang Disesuaikan adalah harga yang disesuaikan dengan pemisahan saham. Ang Adjusted Shares ay ang jumlah saham yang disesuaikan dengan pemisahan saham (stock split).
Rekam Jejak Penjualan Orang Dalam - Analisis Kerugian Jangka Pendek
Dalam bagian ini, kami menganalisis penghindaran kerugian jangka pendek dari setiap penjualan dalam pasar terbuka yang tidak direncanakan oleh orang dalam yang dilakukan di APLS / Apellis Pharmaceuticals, Inc.. Pola penghindaran kerugian yang konsisten dapat menunjukkan bahwa transaksi penjualan di masa mendatang dapat memprediksi penurunan harga. Analisis ini berlaku untuk satu tahun setelah setiap perdagangan, dan hasilnya bersifat teoretis .
Tabel berikut menunjukkan penjualan pasar terbuka terbaru yang bukan bagian dari rencana perdagangan otomatis.
Harga yang Disesuaikan adalah harga yang disesuaikan dengan pemisahan saham. Ang Adjusted Shares ay ang jumlah saham yang disesuaikan dengan pemisahan saham (stock split).
Riwayat Transaksi
Klik ikon tautan untuk melihat riwayat transaksi lengkap. Transaksi yang dilaporkan sebagai bagian dari rencana perdagangan otomatis 10b5-1 akan memiliki tanda X di kolom yang bertanda 10b-5.
| Berkas Tanggal |
Perdagangan Tanggal |
Formulir | Orang Dalam | Ticker | Judul Keamanan | Kode | Langsung | Latihan Harga |
Satuan Harga |
Unit Diubah |
Nilai Diubah (1 ribu) |
Sisa Pilihan |
Sisa Saham |
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2025-09-03 | 2025-09-02 | 4 | Chopas James George | APLS | Common Stock | D | 28.0770 | -548 | -15 | 53,657 | ||||
| 2025-09-03 | 2025-09-02 | 4 | Boucher Kelley | APLS | Common Stock | D | 30,476 | 97,658 | ||||||
| 2025-09-02 | 2025-08-26 | 4 | MELTZER LESLIE | APLS | Common Stock | D | 61,804 | 61,804 | ||||||
| 2025-08-29 | 2025-08-28 | 4 | Francois Cedric Indirect Owner (The Cedric Francois Irrevocable Trust of 2023 - 2) | APLS | Common Stock | I | 28.3900 | -49,963 | -1,418 | 307,946 | ||||
| 2025-08-29 | 2025-08-27 | 4 | Francois Cedric Indirect Owner (The Cedric Francois Irrevocable Trust of 2023 - 2) | APLS | Common Stock | I | 28.1900 | -175,037 | -4,934 | 357,909 | ||||
| 2025-08-19 | 2025-08-18 | 4 | Watson David O. | APLS | Common Stock | D | 27.8000 | -5,000 | -139 | 123,730 | ||||
| 2025-07-18 | 2025-07-17 | 4 | Francois Cedric | APLS | Common Stock | D | 20.2147 | -19,725 | -399 | 331,605 | ||||
| 2025-07-18 | 2025-07-17 | 4 | Francois Cedric | APLS | Common Stock | D | 4.3100 | 8,997 | 39 | 351,330 | ||||
| 2025-07-18 | 2025-07-16 | 4 | Watson David O. | APLS | Common Stock | D | 19.5500 | -5,000 | -98 | 128,730 | ||||
| 2025-07-16 | 2025-07-15 | 4 | Francois Cedric | APLS | Common Stock | D | 20.0884 | -1,900 | -38 | 342,333 | ||||
| 2025-07-16 | 2025-07-15 | 4 | Francois Cedric | APLS | Common Stock | D | 4.3100 | 800 | 3 | 344,233 | ||||
| 2025-07-16 | 2025-07-14 | 4 | Francois Cedric | APLS | Common Stock | D | 20.1864 | -137,465 | -2,775 | 343,433 | ||||
| 2025-07-16 | 2025-07-14 | 4 | Francois Cedric | APLS | Common Stock | D | 4.3100 | 65,203 | 281 | 480,898 | ||||
| 2025-06-20 | 2025-06-18 | 4 | Chopas James George | APLS | Common Stock | D | 6,250 | 54,205 | ||||||
| 2025-06-18 | 2025-06-16 | 4 | Watson David O. | APLS | Common Stock | D | 18.7700 | -5,000 | -94 | 133,730 | ||||
| 2025-06-11 | 2025-06-09 | 4 | Boucher Kelley | APLS | Common Stock | D | 45,095 | 67,182 | ||||||
| 2025-05-29 | 2025-05-28 | 4 | Boucher Kelley | APLS | Common Stock | D | 22,087 | 22,087 | ||||||
| 2025-05-22 | 2025-05-21 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 3.7600 | 12,780 | 48 | 1,160,496 | ||||
| 2025-04-21 | 2025-04-17 | 4 | WHEELER CRAIG A | APLS | Common Stock | D | 16,483 | 16,483 | ||||||
| 2025-03-18 | 2025-03-17 | 4 | Chopas James George | APLS | Common Stock | D | 24.8237 | -183 | -5 | 47,955 | ||||
| 2025-03-06 | 2025-03-05 | 4 | Watson David O. | APLS | Common Stock | D | 25.1013 | -5,569 | -140 | 138,730 | ||||
| 2025-03-06 | 2025-03-04 | 4 | Watson David O. Indirect Owner (Custodial Account for Son) | APLS | Common Stock | I | 6,667 | 10,000 | ||||||
| 2025-03-06 | 2025-03-04 | 4 | Watson David O. Indirect Owner (The Watson Education Trust) | APLS | Common Stock | I | -6,667 | 0 | ||||||
| 2025-02-12 | 2025-02-11 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 28.5388 | -363 | -10 | 83,945 | ||||
| 2025-01-30 | 2025-01-29 | 4 | Watson David O. | APLS | Common Stock | D | 29.5236 | -695 | -21 | 144,299 | ||||
| 2025-01-30 | 2025-01-29 | 4 | Townsend Adam J. | APLS | Common Stock | D | 29.5236 | -695 | -21 | 84,050 | ||||
| 2025-01-30 | 2025-01-29 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 29.5236 | -546 | -16 | 128,665 | ||||
| 2025-01-30 | 2025-01-29 | 4 | Nicholson Nur | APLS | Common Stock | D | 29.5236 | -825 | -24 | 83,664 | ||||
| 2025-01-30 | 2025-01-29 | 4 | Lewis Karen | APLS | Common Stock | D | 29.5236 | -364 | -11 | 70,251 | ||||
| 2025-01-30 | 2025-01-29 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 29.5236 | -278 | -8 | 55,312 | ||||
| 2025-01-30 | 2025-01-29 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 29.5236 | -826 | -24 | 1,147,716 | ||||
| 2025-01-30 | 2025-01-29 | 4 | Francois Cedric | APLS | Common Stock | D | 29.5236 | -2,824 | -83 | 415,695 | ||||
| 2025-01-30 | 2025-01-29 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 29.5236 | -365 | -11 | 84,308 | ||||
| 2025-01-23 | 2025-01-22 | 4 | Watson David O. | APLS | Common Stock | D | 30.4255 | -3,323 | -101 | 144,994 | ||||
| 2025-01-23 | 2025-01-22 | 4 | Townsend Adam J. | APLS | Common Stock | D | 30.4255 | -3,323 | -101 | 84,745 | ||||
| 2025-01-23 | 2025-01-22 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 30.4255 | -3,088 | -94 | 129,211 | ||||
| 2025-01-23 | 2025-01-22 | 4 | Nicholson Nur | APLS | Common Stock | D | 30.4255 | -3,948 | -120 | 84,489 | ||||
| 2025-01-23 | 2025-01-22 | 4 | Lewis Karen | APLS | Common Stock | D | 30.4255 | -1,751 | -53 | 70,615 | ||||
| 2025-01-23 | 2025-01-22 | 4 | Francois Cedric | APLS | Common Stock | D | 30.4255 | -13,551 | -412 | 418,519 | ||||
| 2025-01-23 | 2025-01-22 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 30.4255 | -1,291 | -39 | 55,590 | ||||
| 2025-01-23 | 2025-01-22 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 30.4255 | -3,948 | -120 | 1,148,542 | ||||
| 2025-01-23 | 2025-01-22 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 30.4255 | -1,396 | -42 | 84,673 | ||||
| 2025-01-23 | 2025-01-22 | 4 | Chopas James George | APLS | Common Stock | D | 30.4255 | -1,096 | -33 | 48,138 | ||||
| 2025-01-21 | 2025-01-21 | 4 | Watson David O. | APLS | Common Stock | D | 42,762 | 148,317 | ||||||
| 2025-01-21 | 2025-01-17 | 4 | Watson David O. | APLS | Common Stock | D | 29.9582 | -2,201 | -66 | 105,555 | ||||
| 2025-01-21 | 2025-01-17 | 4 | Townsend Adam J. | APLS | Common Stock | D | 29.9582 | -2,201 | -66 | 88,068 | ||||
| 2025-01-21 | 2025-01-21 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 45,929 | 132,299 | ||||||
| 2025-01-21 | 2025-01-17 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 29.9582 | -1,730 | -52 | 86,370 | ||||
| 2025-01-21 | 2025-01-21 | 4 | Nicholson Nur | APLS | Common Stock | D | 36,426 | 88,437 | ||||||
| 2025-01-21 | 2025-01-17 | 4 | Nicholson Nur | APLS | Common Stock | D | 29.9582 | -2,145 | -64 | 52,011 | ||||
| 2025-01-21 | 2025-01-21 | 4 | Lewis Karen | APLS | Common Stock | D | 28,508 | 72,366 | ||||||
| 2025-01-21 | 2025-01-17 | 4 | Lewis Karen | APLS | Common Stock | D | 29.9582 | -1,241 | -37 | 43,858 | ||||
| 2025-01-21 | 2025-01-21 | 4 | Francois Cedric | APLS | Common Stock | D | 130,662 | 432,070 | ||||||
| 2025-01-21 | 2025-01-17 | 4 | Francois Cedric | APLS | Common Stock | D | 29.9582 | -6,007 | -180 | 301,408 | ||||
| 2025-01-21 | 2025-01-21 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 15,045 | 1,152,490 | ||||||
| 2025-01-21 | 2025-01-17 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 29.9582 | -750 | -22 | 1,137,445 | ||||
| 2025-01-21 | 2025-01-21 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 28,508 | 86,069 | ||||||
| 2025-01-21 | 2025-01-17 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 29.9582 | -1,235 | -37 | 57,561 | ||||
| 2025-01-21 | 2025-01-21 | 4 | Chopas James George | APLS | Common Stock | D | 12,591 | 49,234 | ||||||
| 2025-01-21 | 2025-01-17 | 4 | Chopas James George | APLS | Common Stock | D | 29.9582 | -715 | -21 | 36,643 | ||||
| 2025-01-21 | 2025-01-21 | 4 | Baumal Caroline | APLS | Common Stock | D | 39,594 | 93,301 | ||||||
| 2025-01-21 | 2025-01-17 | 4 | Baumal Caroline | APLS | Common Stock | D | 29.9582 | -1,853 | -56 | 53,707 | ||||
| 2025-01-14 | 2025-01-13 | 4 | Watson David O. | APLS | Common Stock | D | 28.7021 | -4,965 | -143 | 107,756 | ||||
| 2025-01-14 | 2025-01-13 | 4 | Townsend Adam J. | APLS | Common Stock | D | 28.7021 | -2,685 | -77 | 90,269 | ||||
| 2025-01-14 | 2025-01-13 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 28.7021 | -2,170 | -62 | 88,100 | ||||
| 2025-01-14 | 2025-01-13 | 4 | Nicholson Nur | APLS | Common Stock | D | 28.7021 | -2,632 | -76 | 54,156 | ||||
| 2025-01-14 | 2025-01-13 | 4 | Lewis Karen | APLS | Common Stock | D | 28.7021 | -1,599 | -46 | 45,099 | ||||
| 2025-01-14 | 2025-01-13 | 4 | Francois Cedric | APLS | Common Stock | D | 28.7021 | -6,247 | -179 | 307,415 | ||||
| 2025-01-14 | 2025-01-13 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 28.7021 | -264 | -8 | 56,881 | ||||
| 2025-01-14 | 2025-01-13 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 28.7021 | -2,288 | -66 | 1,138,195 | ||||
| 2025-01-14 | 2025-01-13 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 28.7021 | -1,599 | -46 | 58,796 | ||||
| 2025-01-14 | 2025-01-13 | 4 | Chopas James George | APLS | Common Stock | D | 28.7021 | -783 | -22 | 37,358 | ||||
| 2025-01-10 | 2025-01-08 | 4 | Walbert Keli | APLS | Common Stock | D | 9,090 | 9,090 | ||||||
| 2025-01-08 | 2025-01-06 | 4 | Baumal Caroline | APLS | Common Stock | D | 33.8120 | -2,816 | -95 | 55,560 | ||||
| 2025-01-03 | 2025-01-01 | 4 | O'Brien Stephanie Monaghan | APLS | Common Stock | D | 6,267 | 17,705 | ||||||
| 2025-01-03 | 2025-01-01 | 4 | Machiels Alec | APLS | Common Stock | D | 6,267 | 377,028 | ||||||
| 2025-01-03 | 2025-01-01 | 4 | FONTEYNE PAUL R. | APLS | Common Stock | D | 6,267 | 22,705 | ||||||
| 2025-01-03 | 2025-01-01 | 4 | Dunlop A. Sinclair | APLS | Common Stock | D | 6,267 | 158,393 | ||||||
| 2025-01-03 | 2025-01-01 | 4 | Chan Gerald | APLS | Common Stock | D | 6,267 | 17,705 | ||||||
| 2025-01-03 | 2024-12-31 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 13.8500 | 10,054 | 139 | 90,270 | ||||
| 2025-01-03 | 2024-12-31 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 14.9500 | 1,042 | 16 | 80,216 | ||||
| 2024-12-27 | 2024-12-23 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 33.0900 | -63 | -2 | 57,145 | ||||
| 2024-12-13 | 2024-12-11 | 4 | Watson David O. | APLS | Common Stock | D | 34.2350 | -5,000 | -171 | 112,721 | ||||
| 2024-11-01 | 2024-11-01 | 4 | Francois Cedric Indirect Owner (The Cedric Francois Irrevocable Trust of 2023) | APLS | Common Stock | I | -182,146 | 472,065 | ||||||
| 2024-09-30 | 2024-09-27 | 4 | Watson David O. | APLS | Common Stock | D | 10,569 | 117,721 | ||||||
| 2024-09-30 | 2024-09-27 | 4 | Watson David O. Indirect Owner (The David O. Watson Irrevocable Trust of 2023) | APLS | Common Stock | I | -10,569 | 70,136 | ||||||
| 2024-09-24 | 2024-09-23 | 4 | Dunlop A. Sinclair | APLS | Common Stock | D | 13.1900 | 4,600 | 61 | 152,126 | ||||
| 2024-09-17 | 2024-09-16 | 4 | Dunlop A. Sinclair Indirect Owner (Epidarex) | APLS | Common Stock | I | 36.7900 | -7,524 | -277 | 100,000 | ||||
| 2024-09-17 | 2024-09-16 | 4 | Dunlop A. Sinclair Indirect Owner (Epidarex) | APLS | Common Stock | I | 36.0900 | -29,476 | -1,064 | 107,524 | ||||
| 2024-09-17 | 2024-09-16 | 4 | Chopas James George | APLS | Common Stock | D | 36.2060 | -192 | -7 | 38,141 | ||||
| 2024-09-04 | 2024-09-03 | 4 | Chopas James George | APLS | Common Stock | D | 39.4910 | -550 | -22 | 38,333 | ||||
| 2024-08-13 | 2024-08-12 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 13.8500 | 5,201 | 72 | 60,395 | ||||
| 2024-07-01 | 2024-06-28 | 4 | Dunlop A. Sinclair | APLS | Common Stock | D | 13.1900 | 900 | 12 | 134,418 | ||||
| 2024-06-21 | 2024-06-21 | 4 | Dunlop A. Sinclair Indirect Owner (Epidarex) | APLS | Common Stock | I | 39.6300 | -1,695 | -67 | 136,998 | ||||
| 2024-06-21 | 2024-06-21 | 4 | Dunlop A. Sinclair Indirect Owner (Epidarex) | APLS | Common Stock | I | 39.2200 | -35,305 | -1,385 | 138,693 | ||||
| 2024-05-21 | 2024-05-20 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 3.7600 | 24,500 | 92 | 1,140,483 | ||||
| 2024-05-09 | 2024-05-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 44.0250 | -100 | -4 | 1,115,983 | ||||
| 2024-05-09 | 2024-05-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 42.8490 | -22,472 | -963 | 1,116,083 | ||||
| 2024-05-09 | 2024-05-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 42.1504 | -56,335 | -2,375 | 1,138,555 | ||||
| 2024-05-09 | 2024-05-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 4.3100 | 78,907 | 340 | 1,194,890 | ||||
| 2024-04-19 | 2024-04-18 | 4 | Sullivan Timothy Eugene Indirect Owner (The Timothy E Sullivan Irrevocable Trust of 2023) | APLS | Common Stock | I | 14,164 | 70,396 | ||||||
| 2024-04-19 | 2024-04-18 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | -14,164 | 79,174 | ||||||
| 2024-04-15 | 2024-04-12 | 4 | Dunlop A. Sinclair | APLS | Common Stock | D | 13.1900 | 1,500 | 20 | 133,518 | ||||
| 2024-04-09 | 2024-04-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 54.9152 | -4,728 | -260 | 1,115,983 | ||||
| 2024-04-09 | 2024-04-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 54.1165 | -64,379 | -3,484 | 1,120,711 | ||||
| 2024-04-09 | 2024-04-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 3.7600 | 69,107 | 260 | 1,185,090 | ||||
| 2024-04-02 | 2024-04-01 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 58.6600 | -4,000 | -235 | 93,338 | ||||
| 2024-04-02 | 2024-04-01 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 10.0300 | 4,000 | 40 | 97,338 | ||||
| 2024-03-20 | 2024-03-19 | 4 | Dunlop A. Sinclair Indirect Owner (Epidarex) | APLS | Common Stock | I | 57.1790 | -18,681 | -1,068 | 173,998 | ||||
| 2024-03-19 | 2024-03-18 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 56.9000 | -9,913 | -564 | 54,693 | ||||
| 2024-03-18 | 2024-03-15 | 4 | Chopas James George | APLS | Common Stock | D | 56.4610 | -184 | -10 | 38,883 | ||||
| 2024-03-14 | 2024-03-13 | 4 | Nicholson Nur | APLS | Common Stock | D | 58.1335 | -3,452 | -201 | 56,287 | ||||
| 2024-03-14 | 2024-03-13 | 4 | Nicholson Nur | APLS | Common Stock | D | 57.3070 | -7,768 | -445 | 59,739 | ||||
| 2024-03-11 | 2024-03-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 63.3500 | -100 | -6 | 1,115,983 | ||||
| 2024-03-11 | 2024-03-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 62.6896 | -26,257 | -1,646 | 1,116,083 | ||||
| 2024-03-11 | 2024-03-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 61.8754 | -42,750 | -2,645 | 1,142,340 | ||||
| 2024-03-11 | 2024-03-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 3.6700 | 69,107 | 254 | 1,185,090 | ||||
| 2024-03-08 | 2024-03-06 | 4 | Watson David O. | APLS | Common Stock | D | 13.8500 | 3,762 | 52 | 107,152 | ||||
| 2024-03-05 | 2024-03-01 | 4 | Francois Cedric | APLS | Common Stock | D | 65.6800 | -413 | -27 | 313,662 | ||||
| 2024-03-05 | 2024-03-01 | 4 | Francois Cedric | APLS | Common Stock | D | 64.9163 | -116,512 | -7,564 | 314,075 | ||||
| 2024-03-05 | 2024-03-01 | 4 | Francois Cedric | APLS | Common Stock | D | 64.2573 | -62,503 | -4,016 | 430,587 | ||||
| 2024-03-05 | 2024-03-01 | 4 | Francois Cedric | APLS | Common Stock | D | 62.9631 | -41,704 | -2,626 | 493,090 | ||||
| 2024-03-05 | 2024-03-01 | 4 | Francois Cedric | APLS | Common Stock | D | 62.2130 | -28,868 | -1,796 | 534,794 | ||||
| 2024-03-05 | 2024-03-01 | 4 | Francois Cedric | APLS | Common Stock | D | 4.3100 | 200,000 | 862 | 563,662 | ||||
| 2024-03-05 | 2024-03-01 | 4 | Francois Cedric | APLS | Common Stock | D | 3.7600 | 50,000 | 188 | 363,662 | ||||
| 2024-03-05 | 2024-03-01 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 63.9500 | -2,000 | -128 | 93,338 | ||||
| 2024-03-05 | 2024-03-01 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 62.8600 | -4,000 | -251 | 95,338 | ||||
| 2024-03-05 | 2024-03-01 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 10.0300 | 6,000 | 60 | 99,338 | ||||
| 2024-02-13 | 2024-02-12 | 4 | Watson David O. | APLS | Common Stock | D | 67.7669 | -781 | -53 | 103,390 | ||||
| 2024-02-13 | 2024-02-12 | 4 | Townsend Adam J. | APLS | Common Stock | D | 67.7669 | -1,148 | -78 | 92,453 | ||||
| 2024-02-13 | 2024-02-12 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 67.7669 | -1,431 | -97 | 93,338 | ||||
| 2024-02-13 | 2024-02-12 | 4 | Francois Cedric | APLS | Common Stock | D | 67.7669 | -3,962 | -268 | 313,662 | ||||
| 2024-02-13 | 2024-02-12 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 67.7669 | -1,148 | -78 | 1,115,983 | ||||
| 2024-02-13 | 2024-02-12 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 67.7669 | -597 | -40 | 64,606 | ||||
| 2024-01-31 | 2024-01-29 | 4 | Watson David O. | APLS | Common Stock | D | 64.1382 | -906 | -58 | 104,171 | ||||
| 2024-01-31 | 2024-01-29 | 4 | Townsend Adam J. | APLS | Common Stock | D | 64.1382 | -906 | -58 | 93,601 | ||||
| 2024-01-31 | 2024-01-29 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 64.1382 | -906 | -58 | 94,769 | ||||
| 2024-01-31 | 2024-01-29 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 64.1382 | -874 | -56 | 1,117,131 | ||||
| 2024-01-31 | 2024-01-30 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 65.5300 | -971 | -64 | 57,208 | ||||
| 2024-01-31 | 2024-01-29 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 64.1382 | -279 | -18 | 58,179 | ||||
| 2024-01-31 | 2024-01-29 | 4 | Nicholson Nur | APLS | Common Stock | D | 64.1382 | -835 | -54 | 67,507 | ||||
| 2024-01-31 | 2024-01-29 | 4 | Francois Cedric | APLS | Common Stock | D | 64.1382 | -2,843 | -182 | 317,624 | ||||
| 2024-01-31 | 2024-01-30 | 4 | Lewis Karen | APLS | Common Stock | D | 65.5300 | -883 | -58 | 46,387 | ||||
| 2024-01-31 | 2024-01-29 | 4 | Lewis Karen | APLS | Common Stock | D | 64.1382 | -367 | -24 | 47,270 | ||||
| 2024-01-31 | 2024-01-29 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 64.1382 | -367 | -24 | 65,203 | ||||
| 2024-01-24 | 2024-01-23 | 4 | Lewis Karen | APLS | Common Stock | D | 63.6900 | -4,286 | -273 | 47,637 | ||||
| 2024-01-24 | 2024-01-23 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 63.6900 | -7,378 | -470 | 58,458 | ||||
| 2024-01-23 | 2024-01-22 | 4 | Francois Cedric | APLS | Common Stock | D | 64.9960 | -13,431 | -873 | 320,467 | ||||
| 2024-01-23 | 2024-01-22 | 4 | Watson David O. | APLS | Common Stock | D | 64.9960 | -4,184 | -272 | 105,077 | ||||
| 2024-01-23 | 2024-01-22 | 4 | Townsend Adam J. | APLS | Common Stock | D | 64.9960 | -3,413 | -222 | 94,507 | ||||
| 2024-01-23 | 2024-01-22 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 64.9960 | -3,551 | -231 | 95,675 | ||||
| 2024-01-23 | 2024-01-22 | 4 | Nicholson Nur | APLS | Common Stock | D | 64.9960 | -2,593 | -169 | 68,342 | ||||
| 2024-01-23 | 2024-01-22 | 4 | Lewis Karen | APLS | Common Stock | D | 64.9960 | -1,738 | -113 | 51,923 | ||||
| 2024-01-23 | 2024-01-22 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 64.9960 | -1,607 | -104 | 65,836 | ||||
| 2024-01-23 | 2024-01-22 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 64.9960 | -3,913 | -254 | 1,118,005 | ||||
| 2024-01-23 | 2024-01-22 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 64.9960 | -1,384 | -90 | 65,570 | ||||
| 2024-01-23 | 2024-01-22 | 4 | Chopas James George | APLS | Common Stock | D | 64.9960 | -1,061 | -69 | 39,067 | ||||
| 2024-01-18 | 2024-01-17 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 65.5800 | -5,207 | -341 | 67,443 | ||||
| 2024-01-18 | 2024-01-17 | 4 | Lewis Karen | APLS | Common Stock | D | 65.5800 | -3,276 | -215 | 53,661 | ||||
| 2024-01-17 | 2024-01-16 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 66.8086 | -1,632 | -109 | 1,121,918 | ||||
| 2024-01-17 | 2024-01-16 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 6,743 | 1,123,550 | ||||||
| 2024-01-17 | 2024-01-16 | 4 | Chopas James George | APLS | Common Stock | D | 66.8086 | -864 | -58 | 40,128 | ||||
| 2024-01-17 | 2024-01-16 | 4 | Chopas James George | APLS | Common Stock | D | 8,312 | 40,992 | ||||||
| 2024-01-17 | 2024-01-16 | 4 | Lewis Karen | APLS | Common Stock | D | 66.8086 | -1,632 | -109 | 56,937 | ||||
| 2024-01-17 | 2024-01-16 | 4 | Lewis Karen | APLS | Common Stock | D | 16,963 | 58,569 | ||||||
| 2024-01-17 | 2024-01-16 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 66.8086 | -1,631 | -109 | 66,954 | ||||
| 2024-01-17 | 2024-01-16 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 16,963 | 68,585 | ||||||
| 2024-01-17 | 2024-01-16 | 4 | Nicholson Nur | APLS | Common Stock | D | 66.8086 | -1,857 | -124 | 70,935 | ||||
| 2024-01-17 | 2024-01-16 | 4 | Nicholson Nur | APLS | Common Stock | D | 19,508 | 72,792 | ||||||
| 2024-01-17 | 2024-01-16 | 4 | Watson David O. | APLS | Common Stock | D | 66.8086 | -4,240 | -283 | 109,261 | ||||
| 2024-01-17 | 2024-01-16 | 4 | Watson David O. | APLS | Common Stock | D | 23,748 | 113,501 | ||||||
| 2024-01-17 | 2024-01-16 | 4 | Townsend Adam J. | APLS | Common Stock | D | 66.8086 | -2,235 | -149 | 97,920 | ||||
| 2024-01-17 | 2024-01-16 | 4 | Townsend Adam J. | APLS | Common Stock | D | 23,748 | 100,155 | ||||||
| 2024-01-17 | 2024-01-16 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 66.8086 | -2,235 | -149 | 99,226 | ||||
| 2024-01-17 | 2024-01-16 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 23,748 | 101,461 | ||||||
| 2024-01-17 | 2024-01-16 | 4 | Baumal Caroline | APLS | Common Stock | D | 25,445 | 58,376 | ||||||
| 2024-01-17 | 2024-01-16 | 4 | Francois Cedric | APLS | Common Stock | D | 66.8086 | -7,851 | -525 | 333,898 | ||||
| 2024-01-17 | 2024-01-16 | 4 | Francois Cedric | APLS | Common Stock | D | 72,094 | 341,749 | ||||||
| 2024-01-17 | 2024-01-16 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 66.8086 | -438 | -29 | 72,650 | ||||
| 2024-01-17 | 2024-01-16 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 19,508 | 73,088 | ||||||
| 2024-01-05 | 2024-01-04 | 4 | Baumal Caroline | APLS | Common Stock | D | 60.0534 | -2,751 | -165 | 32,931 | ||||
| 2024-01-02 | 2024-01-01 | 4 | FONTEYNE PAUL R. | APLS | Common Stock | D | 3,341 | 16,438 | ||||||
| 2024-01-02 | 2024-01-01 | 4 | O'Brien Stephanie Monaghan | APLS | Common Stock | D | 3,341 | 11,438 | ||||||
| 2024-01-02 | 2024-01-01 | 4 | Chan Gerald | APLS | Common Stock | D | 3,341 | 11,438 | ||||||
| 2024-01-02 | 2024-01-01 | 4 | Dunlop A. Sinclair | APLS | Common Stock | D | 3,341 | 132,018 | ||||||
| 2024-01-02 | 2024-01-01 | 4 | Machiels Alec | APLS | Common Stock | D | 3,341 | 370,761 | ||||||
| 2023-12-28 | 2023-12-27 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 60.2300 | -235 | -14 | 53,580 | ||||
| 2023-12-28 | 2023-12-26 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 57.8609 | -68 | -4 | 53,815 | ||||
| 2023-12-20 | 2023-12-19 | 4 | Watson David O. | APLS | Common Stock | D | 57.3827 | -2,300 | -132 | 89,753 | ||||
| 2023-12-20 | 2023-12-19 | 4 | Watson David O. | APLS | Common Stock | D | 57.0041 | -1,605 | -91 | 92,053 | ||||
| 2023-12-20 | 2023-12-19 | 4 | Watson David O. | APLS | Common Stock | D | 13.8500 | 7,905 | 109 | 93,658 | ||||
| 2023-12-15 | 2023-12-14 | 4 | Dunlop A. Sinclair | APLS | Common Stock | D | 13.1900 | 6,274 | 83 | 128,677 | ||||
| 2023-12-05 | 2023-12-01 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 60.0000 | -10,000 | -600 | 68,299 | ||||
| 2023-12-05 | 2023-12-01 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 13.8500 | 10,000 | 138 | 78,299 | ||||
| 2023-12-05 | 2023-12-01 | 4 | Townsend Adam J. | APLS | Common Stock | D | 61.3052 | -42,443 | -2,602 | 76,407 | ||||
| 2023-12-05 | 2023-12-01 | 4 | Townsend Adam J. | APLS | Common Stock | D | 60.5019 | -67,557 | -4,087 | 118,850 | ||||
| 2023-12-05 | 2023-12-01 | 4 | Townsend Adam J. | APLS | Common Stock | D | 15.0900 | 110,000 | 1,660 | 186,407 | ||||
| 2023-12-05 | 2023-12-01 | 4 | Dunlop A. Sinclair Indirect Owner (Epidarex) | APLS | Common Stock | I | 61.1350 | -24,000 | -1,467 | 192,679 | ||||
| 2023-12-01 | 2023-11-30 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 54.7866 | -300 | -16 | 77,713 | ||||
| 2023-12-01 | 2023-11-30 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 54.7300 | -13,858 | -758 | 78,013 | ||||
| 2023-12-01 | 2023-11-30 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 10.0300 | 14,158 | 142 | 91,871 | ||||
| 2023-11-21 | 2023-11-21 | 4 | Francois Cedric | APLS | Common Stock | D | 48.8000 | -5,000 | -244 | 269,655 | ||||
| 2023-11-21 | 2023-10-17 | 4 | Dunlop A. Sinclair Indirect Owner (Epidarex) | APLS | Common Stock | I | 49.0000 | -24,000 | -1,176 | 216,679 | ||||
| 2023-11-21 | 2023-11-17 | 4 | Dunlop A. Sinclair | APLS | Common Stock | D | 49.9910 | -8,894 | -445 | 122,403 | ||||
| 2023-11-20 | 2023-11-17 | 4 | Machiels Alec | APLS | Common Stock | D | 47.7400 | -1,250 | -60 | 367,420 | ||||
| 2023-11-20 | 2023-11-17 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 1,250 | 3 | 368,670 | ||||
| 2023-11-15 | 2023-11-14 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 3.7600 | 45,000 | 169 | 1,116,807 | ||||
| 2023-11-09 | 2023-11-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 47.2700 | -12,000 | -567 | 1,071,807 | ||||
| 2023-11-09 | 2023-11-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 17,494 | 47 | 1,083,807 | ||||
| 2023-10-24 | 2023-10-23 | 4 | Chopas James George | APLS | Common Stock | D | 46.0362 | -132 | -6 | 32,680 | ||||
| 2023-10-24 | 2023-10-23 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 46.0362 | -131 | -6 | 51,622 | ||||
| 2023-10-18 | 2023-10-17 | 4 | Machiels Alec | APLS | Common Stock | D | 48.5000 | -1,250 | -61 | 367,420 | ||||
| 2023-10-18 | 2023-10-17 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 1,250 | 3 | 368,670 | ||||
| 2023-10-10 | 2023-10-09 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 40.3800 | -12,000 | -485 | 1,066,313 | ||||
| 2023-10-10 | 2023-10-09 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 18,500 | 49 | 1,078,313 | ||||
| 2023-09-20 | 2023-09-19 | 4 | Francois Cedric Indirect Owner (The Cedric Francois Irrevocable Trust of 2023) | APLS | Common Stock | I | 150,000 | 804,211 | ||||||
| 2023-09-20 | 2023-09-19 | 4 | Francois Cedric | APLS | Common Stock | D | -150,000 | 274,655 | ||||||
| 2023-09-19 | 2023-09-18 | 4 | Machiels Alec | APLS | Common Stock | D | 45.0000 | -1,250 | -56 | 367,420 | ||||
| 2023-09-19 | 2023-09-18 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 1,250 | 3 | 368,670 | ||||
| 2023-09-19 | 2023-09-18 | 4 | Nicholson Nur | APLS | Common Stock | D | 46.1470 | -10,631 | -491 | 53,284 | ||||
| 2023-09-19 | 2023-09-18 | 4 | Nicholson Nur | APLS | Common Stock | D | 42.2085 | -9,719 | -410 | 63,915 | ||||
| 2023-09-19 | 2023-09-18 | 4 | Nicholson Nur | APLS | Common Stock | D | 29.7600 | 9,719 | 289 | 73,634 | ||||
| 2023-09-18 | 2023-09-15 | 4 | Machiels Alec | APLS | Common Stock | D | 45.3400 | -1,250 | -57 | 367,420 | ||||
| 2023-09-18 | 2023-09-15 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 1,250 | 3 | 368,670 | ||||
| 2023-09-18 | 2023-09-14 | 4 | Chopas James George | APLS | Common Stock | D | 2,500 | 32,812 | ||||||
| 2023-09-11 | 2023-09-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 42.8700 | -12,000 | -514 | 1,059,813 | ||||
| 2023-09-11 | 2023-09-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 18,500 | 49 | 1,071,813 | ||||
| 2023-09-07 | 2023-09-06 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 43.0100 | -1,756 | -76 | 68,299 | ||||
| 2023-09-01 | 2023-08-31 | 4 | Chopas James George | APLS | Common Stock | D | 41.2260 | -551 | -23 | 30,312 | ||||
| 2023-09-01 | 2023-09-01 | 4 | Francois Cedric | APLS | Common Stock | D | 42.4400 | -10,284 | -436 | 424,655 | ||||
| 2023-09-01 | 2023-09-01 | 4 | Francois Cedric | APLS | Common Stock | D | 41.7025 | -139,716 | -5,827 | 434,939 | ||||
| 2023-09-01 | 2023-09-01 | 4 | Francois Cedric | APLS | Common Stock | D | 2.6700 | 300,000 | 801 | 574,655 | ||||
| 2023-08-09 | 2023-08-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 23.6600 | -12,000 | -284 | 1,053,313 | ||||
| 2023-08-09 | 2023-08-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 18,500 | 49 | 1,065,313 | ||||
| 2023-07-24 | 2023-07-21 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 49,779 | 133 | 367,420 | ||||
| 2023-07-21 | 2023-07-20 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 50,000 | 134 | 317,641 | ||||
| 2023-07-18 | 2023-07-17 | 4 | Machiels Alec | APLS | Common Stock | D | 64.7900 | -1,250 | -81 | 267,641 | ||||
| 2023-07-18 | 2023-07-17 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 1,250 | 3 | 268,891 | ||||
| 2023-07-11 | 2023-07-10 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 84.5500 | -12,000 | -1,015 | 1,046,813 | ||||
| 2023-07-11 | 2023-07-10 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 18,500 | 49 | 1,058,813 | ||||
| 2023-07-06 | 2023-07-03 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 91.0983 | -300 | -27 | 77,713 | ||||
| 2023-07-06 | 2023-07-03 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 90.4165 | -3,287 | -297 | 78,013 | ||||
| 2023-07-06 | 2023-07-03 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 89.4109 | -3,192 | -285 | 81,300 | ||||
| 2023-07-06 | 2023-07-03 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 10.0300 | 6,779 | 68 | 84,492 | ||||
| 2023-07-06 | 2023-07-03 | 4 | Watson David O. | APLS | Common Stock | D | 89.9800 | -8,510 | -766 | 85,753 | ||||
| 2023-06-29 | 2023-06-28 | 4 | Watson David O. Indirect Owner (The David O. Watson Irrevocable Trust of 2023) | APLS | Common Stock | I | 12,750 | 80,705 | ||||||
| 2023-06-29 | 2023-06-28 | 4 | Watson David O. | APLS | Common Stock | D | -12,750 | 94,263 | ||||||
| 2023-06-21 | 2023-06-20 | 4 | Machiels Alec | APLS | Common Stock | D | 88.4100 | -1,250 | -111 | 267,641 | ||||
| 2023-06-21 | 2023-06-20 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 1,250 | 3 | 268,891 | ||||
| 2023-06-09 | 2023-06-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 91.3500 | -12,000 | -1,096 | 1,040,313 | ||||
| 2023-06-09 | 2023-06-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 18,500 | 49 | 1,052,313 | ||||
| 2023-06-06 | 2023-06-05 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 89.8259 | -30,506 | -2,740 | 77,713 | ||||
| 2023-06-06 | 2023-06-05 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 88.3649 | -7,064 | -624 | 108,219 | ||||
| 2023-06-06 | 2023-06-05 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 87.7886 | -30,609 | -2,687 | 115,283 | ||||
| 2023-06-06 | 2023-06-05 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 90.6044 | -1,600 | -145 | 145,892 | ||||
| 2023-06-06 | 2023-06-05 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 10.0300 | 69,779 | 700 | 147,492 | ||||
| 2023-06-02 | 2023-06-01 | 4 | Lewis Karen | APLS | Common Stock | D | 86.0000 | -5,000 | -430 | 41,504 | ||||
| 2023-06-02 | 2023-06-01 | 4 | Lewis Karen | APLS | Common Stock | D | 34.1100 | 5,000 | 171 | 46,504 | ||||
| 2023-05-25 | 2023-05-24 | 4 | Francois Cedric Indirect Owner (The Cedric Francois Irrevocable Trust of 2023) | APLS | Common Stock | I | 20,000 | 654,211 | ||||||
| 2023-05-25 | 2023-05-24 | 4 | Francois Cedric | APLS | Common Stock | D | -20,000 | 274,655 | ||||||
| 2023-05-18 | 2023-05-17 | 4 | Machiels Alec | APLS | Common Stock | D | 88.6600 | -1,250 | -111 | 267,641 | ||||
| 2023-05-18 | 2023-05-17 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 1,250 | 3 | 268,891 | ||||
| 2023-05-18 | 2023-05-17 | 4 | Francois Cedric | APLS | Common Stock | D | 2.6700 | 20,000 | 53 | 294,655 | ||||
| 2023-05-18 | 2023-05-16 | 4 | Francois Cedric | APLS | Common Stock | D | 87.6739 | -2,120 | -186 | 274,655 | ||||
| 2023-05-18 | 2023-05-16 | 4 | Francois Cedric | APLS | Common Stock | D | 87.0163 | -7,528 | -655 | 276,775 | ||||
| 2023-05-18 | 2023-05-16 | 4 | Francois Cedric | APLS | Common Stock | D | 85.9012 | -3,007 | -258 | 284,303 | ||||
| 2023-05-18 | 2023-05-16 | 4 | Francois Cedric | APLS | Common Stock | D | 85.0089 | -14,611 | -1,242 | 287,310 | ||||
| 2023-05-18 | 2023-05-16 | 4 | Francois Cedric | APLS | Common Stock | D | 83.8450 | -1,800 | -151 | 301,921 | ||||
| 2023-05-18 | 2023-05-16 | 4 | Francois Cedric | APLS | Common Stock | D | 83.1711 | -934 | -78 | 303,721 | ||||
| 2023-05-18 | 2023-05-16 | 4 | Francois Cedric | APLS | Common Stock | D | 2.6700 | 30,000 | 80 | 304,655 | ||||
| 2023-05-09 | 2023-05-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 92.3900 | -12,000 | -1,109 | 1,033,813 | ||||
| 2023-05-09 | 2023-05-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 18,500 | 49 | 1,045,813 | ||||
| 2023-05-04 | 2023-05-03 | 4 | Townsend Adam J. | APLS | Common Stock | D | 82.7100 | -5,000 | -414 | 75,995 | ||||
| 2023-05-04 | 2023-05-03 | 4 | Townsend Adam J. | APLS | Common Stock | D | 15.0900 | 5,000 | 75 | 80,995 | ||||
| 2023-05-03 | 2023-05-03 | 4 | Sullivan Timothy Eugene Indirect Owner (The Timothy E Sullivan Irrevocable Trust of 2023) | APLS | Common Stock | I | 20,000 | 56,232 | ||||||
| 2023-05-03 | 2023-05-03 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | -20,000 | 77,713 | ||||||
| 2023-04-28 | 2023-04-27 | 4 | Francois Cedric Indirect Owner (The Cedric Francois Irrevocable Trust of 2023 - 2) | APLS | Common Stock | I | 382,946 | 382,946 | ||||||
| 2023-04-28 | 2023-04-27 | 4 | Francois Cedric | APLS | Common Stock | D | -382,946 | 274,655 | ||||||
| 2023-04-24 | 2023-04-21 | 4 | Watson David O. Indirect Owner (The David O. Watson Irrevocable Trust of 2023) | APLS | Common Stock | I | 67,955 | 67,955 | ||||||
| 2023-04-24 | 2023-04-21 | 4 | Watson David O. | APLS | Common Stock | D | -67,955 | 107,013 | ||||||
| 2023-04-20 | 2023-04-19 | 4 | Francois Cedric | APLS | Common Stock | D | 2.6700 | 20,000 | 53 | 657,601 | ||||
| 2023-04-20 | 2023-04-18 | 4 | Francois Cedric | APLS | Common Stock | D | 82.0240 | -30,000 | -2,461 | 637,601 | ||||
| 2023-04-20 | 2023-04-18 | 4 | Francois Cedric | APLS | Common Stock | D | 2.6700 | 30,000 | 80 | 667,601 | ||||
| 2023-04-20 | 2023-04-19 | 4 | Sullivan Timothy Eugene Indirect Owner (The Timothy E Sullivan Irrevocable Trust of 2023) | APLS | Common Stock | I | 36,232 | 36,232 | ||||||
| 2023-04-20 | 2023-04-19 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | -36,232 | 97,713 | ||||||
| 2023-04-18 | 2023-04-17 | 4 | Machiels Alec | APLS | Common Stock | D | 81.0500 | -1,250 | -101 | 267,641 | ||||
| 2023-04-18 | 2023-04-17 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 1,250 | 3 | 268,891 | ||||
| 2023-04-11 | 2023-04-10 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 78.2100 | -12,000 | -939 | 1,027,313 | ||||
| 2023-04-11 | 2023-04-10 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 18,500 | 49 | 1,039,313 | ||||
| 2023-04-05 | 2023-04-05 | 4 | Francois Cedric Indirect Owner (The Cedric Francois Irrevocable Trust of 2023) | APLS | Common Stock | I | 26,990 | 634,211 | ||||||
| 2023-04-05 | 2023-04-05 | 4 | Francois Cedric | APLS | Common Stock | D | -26,990 | 637,601 | ||||||
| 2023-04-05 | 2023-04-04 | 4 | Francois Cedric Indirect Owner (The Cedric Francois Irrevocable Trust of 2023) | APLS | Common Stock | I | 380,000 | 607,221 | ||||||
| 2023-04-05 | 2023-04-04 | 4 | Francois Cedric | APLS | Common Stock | D | -380,000 | 664,591 | ||||||
| 2023-04-05 | 2023-04-03 | 4 | Francois Cedric Indirect Owner (The Cedric Francois Irrevocable Trust of 2023) | APLS | Common Stock | I | 227,221 | 227,221 | ||||||
| 2023-04-05 | 2023-04-03 | 4 | Francois Cedric | APLS | Common Stock | D | -227,221 | 1,044,591 | ||||||
| 2023-04-05 | 2023-04-03 | 4 | Dunlop A. Sinclair | APLS | Common Stock | D | 74.0500 | -500 | -37 | 131,297 | ||||
| 2023-04-05 | 2023-04-03 | 4 | Lewis Karen | APLS | Common Stock | D | 75.0000 | -5,000 | -375 | 41,430 | ||||
| 2023-04-05 | 2023-04-03 | 4 | Lewis Karen | APLS | Common Stock | D | 34.1100 | 5,000 | 171 | 46,430 | ||||
| 2023-04-05 | 2023-04-03 | 4 | Townsend Adam J. | APLS | Common Stock | D | 74.0500 | -5,000 | -370 | 75,995 | ||||
| 2023-04-05 | 2023-04-03 | 4 | Townsend Adam J. | APLS | Common Stock | D | 15.0900 | 5,000 | 75 | 80,995 | ||||
| 2023-03-23 | 2023-03-22 | 4 | Francois Cedric | APLS | Common Stock | D | 13.8500 | 7,221 | 100 | 1,271,812 | ||||
| 2023-03-23 | 2023-03-22 | 4 | Francois Cedric | APLS | Common Stock | D | 3.7600 | 100,000 | 376 | 1,264,591 | ||||
| 2023-03-23 | 2023-03-22 | 4 | Francois Cedric | APLS | Common Stock | D | 2.6700 | 20,000 | 53 | 1,164,591 | ||||
| 2023-03-23 | 2023-03-21 | 4 | Francois Cedric | APLS | Common Stock | D | 62.7444 | -30,000 | -1,882 | 1,144,591 | ||||
| 2023-03-23 | 2023-03-21 | 4 | Francois Cedric | APLS | Common Stock | D | 2.6700 | 30,000 | 80 | 1,174,591 | ||||
| 2023-03-21 | 2023-03-17 | 4 | Machiels Alec | APLS | Common Stock | D | 64.0300 | -1,250 | -80 | 267,641 | ||||
| 2023-03-21 | 2023-03-17 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 1,250 | 3 | 268,891 | ||||
| 2023-03-10 | 2023-03-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 63.7900 | -12,000 | -765 | 1,020,813 | ||||
| 2023-03-10 | 2023-03-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 18,500 | 49 | 1,032,813 | ||||
| 2023-03-07 | 2023-03-03 | 4 | Townsend Adam J. | APLS | Common Stock | D | 63.8400 | -5,000 | -319 | 75,995 | ||||
| 2023-03-07 | 2023-03-03 | 4 | Townsend Adam J. | APLS | Common Stock | D | 15.0900 | 5,000 | 75 | 80,995 | ||||
| 2023-03-02 | 2023-03-01 | 4 | Dunlop A. Sinclair | APLS | Common Stock | D | 65.3300 | -500 | -33 | 131,797 | ||||
| 2023-03-01 | 2023-02-27 | 4 | Francois Cedric | APLS | Common Stock | D | 3.7600 | 100,000 | 376 | 1,144,591 | ||||
| 2023-02-27 | 2023-02-23 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 68.7600 | -1,646 | -113 | 53,883 | ||||
| 2023-02-27 | 2023-02-23 | 4 | Lewis Karen | APLS | Common Stock | D | 68.7600 | -1,104 | -76 | 41,430 | ||||
| 2023-02-22 | 2023-02-21 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 58.5000 | -825 | -48 | 55,529 | ||||
| 2023-02-22 | 2023-02-21 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 9,886 | 56,354 | ||||||
| 2023-02-22 | 2023-02-21 | 4 | Chopas James George | APLS | Common Stock | D | 58.5000 | -334 | -20 | 30,863 | ||||
| 2023-02-22 | 2023-02-21 | 4 | Chopas James George | APLS | Common Stock | D | 4,044 | 31,197 | ||||||
| 2023-02-22 | 2023-02-21 | 4 | Lewis Karen | APLS | Common Stock | D | 58.5000 | -553 | -32 | 42,534 | ||||
| 2023-02-22 | 2023-02-21 | 4 | Lewis Karen | APLS | Common Stock | D | 6,628 | 43,087 | ||||||
| 2023-02-22 | 2023-02-21 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 58.5000 | -1,195 | -70 | 1,014,313 | ||||
| 2023-02-22 | 2023-02-21 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 9,886 | 1,015,508 | ||||||
| 2023-02-22 | 2023-02-21 | 4 | Watson David O. | APLS | Common Stock | D | 58.5000 | -825 | -48 | 174,968 | ||||
| 2023-02-22 | 2023-02-21 | 4 | Watson David O. | APLS | Common Stock | D | 9,886 | 175,793 | ||||||
| 2023-02-22 | 2023-02-21 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 58.5000 | -715 | -42 | 69,643 | ||||
| 2023-02-22 | 2023-02-21 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 9,886 | 70,358 | ||||||
| 2023-02-22 | 2023-02-21 | 4 | Francois Cedric | APLS | Common Stock | D | 58.5000 | -1,602 | -94 | 1,044,591 | ||||
| 2023-02-22 | 2023-02-21 | 4 | Francois Cedric | APLS | Common Stock | D | 13,908 | 1,046,193 | ||||||
| 2023-02-22 | 2023-02-21 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 58.5000 | -974 | -57 | 133,945 | ||||
| 2023-02-22 | 2023-02-21 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 11,683 | 134,919 | ||||||
| 2023-02-22 | 2023-02-21 | 4 | Townsend Adam J. | APLS | Common Stock | D | 58.5000 | -1,041 | -61 | 75,995 | ||||
| 2023-02-22 | 2023-02-21 | 4 | Townsend Adam J. | APLS | Common Stock | D | 9,886 | 77,036 | ||||||
| 2023-02-22 | 2023-02-21 | 4 | Nicholson Nur | APLS | Common Stock | D | 58.5000 | -825 | -48 | 63,503 | ||||
| 2023-02-22 | 2023-02-21 | 4 | Nicholson Nur | APLS | Common Stock | D | 9,886 | 64,328 | ||||||
| 2023-02-22 | 2023-02-21 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 58.5000 | -441 | -26 | 51,341 | ||||
| 2023-02-22 | 2023-02-21 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 5,280 | 51,782 | ||||||
| 2023-02-21 | 2023-02-17 | 4 | Machiels Alec | APLS | Common Stock | D | 52.3800 | -1,250 | -65 | 267,641 | ||||
| 2023-02-21 | 2023-02-17 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 1,250 | 3 | 268,891 | ||||
| 2023-02-14 | 2023-02-10 | 4 | Watson David O. | APLS | Common Stock | D | 51.2100 | -532 | -27 | 165,907 | ||||
| 2023-02-14 | 2023-02-10 | 4 | Townsend Adam J. | APLS | Common Stock | D | 51.2100 | -782 | -40 | 67,150 | ||||
| 2023-02-14 | 2023-02-10 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 51.2100 | -975 | -50 | 123,236 | ||||
| 2023-02-14 | 2023-02-10 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 51.2100 | -678 | -35 | 60,472 | ||||
| 2023-02-14 | 2023-02-10 | 4 | Francois Cedric | APLS | Common Stock | D | 51.2100 | -3,958 | -203 | 1,032,285 | ||||
| 2023-02-14 | 2023-02-10 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 51.2100 | -670 | -34 | 46,502 | ||||
| 2023-02-14 | 2023-02-10 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 51.2100 | -1,134 | -58 | 1,005,622 | ||||
| 2023-02-10 | 2023-02-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 54.4500 | -12,000 | -653 | 1,006,756 | ||||
| 2023-02-10 | 2023-02-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 18,500 | 49 | 1,018,756 | ||||
| 2023-02-06 | 2023-02-03 | 4 | Townsend Adam J. | APLS | Common Stock | D | 55.8500 | -5,000 | -279 | 67,932 | ||||
| 2023-02-06 | 2023-02-03 | 4 | Townsend Adam J. | APLS | Common Stock | D | 15.0900 | 5,000 | 75 | 72,932 | ||||
| 2023-02-02 | 2023-02-01 | 4 | Dunlop A. Sinclair | APLS | Common Stock | D | 52.6100 | -500 | -26 | 132,297 | ||||
| 2023-01-31 | 2023-01-30 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 52.7600 | -883 | -47 | 46,468 | ||||
| 2023-01-31 | 2023-01-30 | 4 | Lewis Karen | APLS | Common Stock | D | 52.7600 | -883 | -47 | 36,459 | ||||
| 2023-01-30 | 2023-01-27 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 52.7700 | -551 | -29 | 124,211 | ||||
| 2023-01-30 | 2023-01-27 | 4 | Townsend Adam J. | APLS | Common Stock | D | 52.7700 | -551 | -29 | 67,932 | ||||
| 2023-01-30 | 2023-01-27 | 4 | Watson David O. | APLS | Common Stock | D | 52.7700 | -551 | -29 | 166,439 | ||||
| 2023-01-30 | 2023-01-27 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 52.7700 | -542 | -29 | 61,150 | ||||
| 2023-01-30 | 2023-01-27 | 4 | Lewis Karen | APLS | Common Stock | D | 52.7700 | -367 | -19 | 37,342 | ||||
| 2023-01-30 | 2023-01-27 | 4 | Nicholson Nur | APLS | Common Stock | D | 52.7700 | -551 | -29 | 54,442 | ||||
| 2023-01-30 | 2023-01-27 | 4 | Francois Cedric | APLS | Common Stock | D | 52.7700 | -2,879 | -152 | 1,036,243 | ||||
| 2023-01-30 | 2023-01-27 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 52.7700 | -367 | -19 | 47,351 | ||||
| 2023-01-30 | 2023-01-27 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 52.7700 | -832 | -44 | 1,000,256 | ||||
| 2023-01-30 | 2023-01-27 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 52.7700 | -367 | -19 | 47,172 | ||||
| 2023-01-25 | 2023-01-23 | 4 | Lewis Karen | APLS | Common Stock | D | 51.5800 | -2,955 | -152 | 37,709 | ||||
| 2023-01-25 | 2023-01-23 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 51.5800 | -4,479 | -231 | 47,718 | ||||
| 2023-01-24 | 2023-01-20 | 4 | Brown Victoria L. | APLS | Common Stock | D | 52.0500 | -1,412 | -73 | 23,556 | ||||
| 2023-01-24 | 2023-01-20 | 4 | Chopas James George | APLS | Common Stock | D | 52.0500 | -919 | -48 | 27,153 | ||||
| 2023-01-24 | 2023-01-20 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 52.0500 | -2,326 | -121 | 1,001,088 | ||||
| 2023-01-24 | 2023-01-20 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 52.0500 | -2,033 | -106 | 52,197 | ||||
| 2023-01-24 | 2023-01-20 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 52.0500 | -2,379 | -124 | 124,762 | ||||
| 2023-01-24 | 2023-01-20 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 52.0500 | -1,149 | -60 | 47,539 | ||||
| 2023-01-24 | 2023-01-20 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 52.0500 | -2,015 | -105 | 61,692 | ||||
| 2023-01-24 | 2023-01-20 | 4 | Francois Cedric | APLS | Common Stock | D | 52.0500 | -9,453 | -492 | 1,039,122 | ||||
| 2023-01-24 | 2023-01-20 | 4 | Lewis Karen | APLS | Common Stock | D | 52.0500 | -1,411 | -73 | 40,664 | ||||
| 2023-01-24 | 2023-01-20 | 4 | Nicholson Nur | APLS | Common Stock | D | 52.0500 | -2,034 | -106 | 54,993 | ||||
| 2023-01-24 | 2023-01-20 | 4 | Townsend Adam J. | APLS | Common Stock | D | 52.0500 | -1,912 | -100 | 68,483 | ||||
| 2023-01-24 | 2023-01-20 | 4 | Watson David O. | APLS | Common Stock | D | 52.0500 | -2,034 | -106 | 166,990 | ||||
| 2023-01-19 | 2023-01-17 | 4 | Machiels Alec | APLS | Common Stock | D | 52.4200 | -1,250 | -66 | 267,641 | ||||
| 2023-01-19 | 2023-01-17 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 1,250 | 3 | 268,891 | ||||
| 2023-01-17 | 2023-01-12 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 27,488 | 127,141 | ||||||
| 2023-01-17 | 2022-04-25 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | -3,750 | 99,653 | ||||||
| 2023-01-17 | 2023-01-12 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 22,580 | 63,707 | ||||||
| 2023-01-17 | 2023-01-12 | 4 | Francois Cedric | APLS | Common Stock | D | 83,447 | 1,048,575 | ||||||
| 2023-01-17 | 2023-01-12 | 4 | Watson David O. | APLS | Common Stock | D | 29,452 | 169,024 | ||||||
| 2023-01-17 | 2023-01-12 | 4 | Watson David O. | APLS | Common Stock | D | 24,003 | 139,572 | ||||||
| 2023-01-17 | 2023-01-12 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 19,634 | 1,003,414 | ||||||
| 2023-01-17 | 2023-01-12 | 4 | Townsend Adam J. | APLS | Common Stock | D | 27,488 | 70,395 | ||||||
| 2023-01-17 | 2023-01-12 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 19,634 | 48,688 | ||||||
| 2023-01-17 | 2023-01-12 | 4 | Nicholson Nur | APLS | Common Stock | D | 22,580 | 57,027 | ||||||
| 2023-01-17 | 2022-04-25 | 4 | Nicholson Nur | APLS | Common Stock | D | -1,875 | 33,680 | ||||||
| 2023-01-17 | 2023-01-12 | 4 | Lewis Karen | APLS | Common Stock | D | 19,634 | 42,075 | ||||||
| 2023-01-17 | 2022-04-25 | 4 | Lewis Karen | APLS | Common Stock | D | -1,250 | 22,224 | ||||||
| 2023-01-17 | 2023-01-12 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 22,580 | 54,230 | ||||||
| 2023-01-17 | 2023-01-12 | 4 | Chopas James George | APLS | Common Stock | D | 9,621 | 28,072 | ||||||
| 2023-01-10 | 2023-01-09 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 46.0800 | -12,000 | -553 | 983,780 | ||||
| 2023-01-10 | 2023-01-09 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 18,500 | 49 | 995,780 | ||||
| 2023-01-09 | 2023-01-05 | 4 | Grossi Federico | APLS | Common Stock | D | 48.7900 | -2,500 | -122 | 94,884 | ||||
| 2023-01-09 | 3 | Baumal Caroline | APLS | Common Stock | D | 133 | ||||||||
| 2023-01-05 | 2023-01-03 | 4 | Baumal Caroline | APLS | Common Stock | D | 35,549 | 35,682 | ||||||
| 2023-01-05 | 2023-01-03 | 4 | Dunlop A. Sinclair | APLS | Common Stock | D | 50.7000 | -500 | -25 | 132,797 | ||||
| 2023-01-05 | 2023-01-03 | 4 | Townsend Adam J. | APLS | Common Stock | D | 50.7000 | -5,000 | -254 | 42,907 | ||||
| 2023-01-05 | 2023-01-03 | 4 | Townsend Adam J. | APLS | Common Stock | D | 15.0900 | 5,000 | 75 | 47,907 | ||||
| 2023-01-05 | 3 | Baumal Caroline | APLS | Common Stock | D | 133 | ||||||||
| 2023-01-04 | 2023-01-01 | 4 | Machiels Alec | APLS | Common Stock | D | 3,867 | 267,641 | ||||||
| 2023-01-04 | 2023-01-01 | 4 | Chan Gerald | APLS | Common Stock | D | 3,867 | 8,097 | ||||||
| 2023-01-04 | 2023-01-01 | 4 | Dunlop A. Sinclair | APLS | Common Stock | D | 3,867 | 133,297 | ||||||
| 2023-01-04 | 2023-01-01 | 4 | O'Brien Stephanie Monaghan | APLS | Common Stock | D | 3,867 | 8,097 | ||||||
| 2023-01-04 | 2023-01-01 | 4 | FONTEYNE PAUL R. | APLS | Common Stock | D | 3,867 | 13,097 | ||||||
| 2022-12-30 | 2022-12-29 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 3.6700 | 7,000 | 26 | 977,280 | ||||
| 2022-12-23 | 2022-12-22 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 51.6800 | -89 | -5 | 31,650 | ||||
| 2022-12-23 | 2022-04-25 | 4 | Eisele Jeffrey | APLS | Common Stock | D | -1,250 | 31,739 | ||||||
| 2022-12-21 | 2022-12-19 | 4 | Francois Cedric | APLS | Common Stock | D | 52.0697 | -24,449 | -1,273 | 965,128 | ||||
| 2022-12-21 | 2022-12-19 | 4 | Francois Cedric | APLS | Common Stock | D | 51.9678 | -3,751 | -195 | 989,577 | ||||
| 2022-12-21 | 2022-12-19 | 4 | Francois Cedric | APLS | Common Stock | D | 14.9500 | 6,688 | 100 | 993,328 | ||||
| 2022-12-21 | 2022-12-19 | 4 | Francois Cedric | APLS | Common Stock | D | 3.7600 | 15,000 | 56 | 986,640 | ||||
| 2022-12-21 | 2022-12-19 | 4 | Francois Cedric | APLS | Common Stock | D | 2.6700 | 28,200 | 75 | 971,640 | ||||
| 2022-12-21 | 2022-04-25 | 4 | Francois Cedric | APLS | Common Stock | D | -12,500 | 943,440 | ||||||
| 2022-12-19 | 2022-12-15 | 4 | Machiels Alec | APLS | Common Stock | D | 52.3500 | -1,250 | -65 | 263,774 | ||||
| 2022-12-19 | 2022-12-15 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 1,250 | 3 | 265,024 | ||||
| 2022-12-12 | 2022-12-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 47.5000 | -12,000 | -570 | 970,280 | ||||
| 2022-12-12 | 2022-12-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 18,500 | 49 | 982,280 | ||||
| 2022-12-07 | 2022-12-05 | 4 | Townsend Adam J. | APLS | Common Stock | D | 50.3800 | -5,000 | -252 | 42,907 | ||||
| 2022-12-07 | 2022-12-05 | 4 | Townsend Adam J. | APLS | Common Stock | D | 15.0900 | -5,000 | -75 | 47,907 | ||||
| 2022-12-02 | 2022-12-01 | 4 | Grossi Federico | APLS | Common Stock | D | 49.9300 | -2,500 | -125 | 97,384 | ||||
| 2022-12-02 | 2022-12-01 | 4 | Dunlop A. Sinclair | APLS | Common Stock | D | 49.9300 | -500 | -25 | 129,430 | ||||
| 2022-11-17 | 2022-11-15 | 4 | Machiels Alec | APLS | Common Stock | D | 48.0100 | -1,250 | -60 | 263,774 | ||||
| 2022-11-17 | 2022-11-15 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 1,250 | 3 | 265,024 | ||||
| 2022-11-10 | 2022-11-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 46.4700 | -12,000 | -558 | 963,780 | ||||
| 2022-11-10 | 2022-11-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 18,500 | 49 | 975,780 | ||||
| 2022-11-07 | 2022-11-03 | 4 | Townsend Adam J. | APLS | Common Stock | D | 58.5400 | -5,000 | -293 | 42,907 | ||||
| 2022-11-07 | 2022-11-03 | 4 | Townsend Adam J. | APLS | Common Stock | D | 15.0900 | -5,000 | -75 | 47,907 | ||||
| 2022-11-03 | 2022-11-01 | 4 | Grossi Federico | APLS | Common Stock | D | 60.8300 | -2,500 | -152 | 99,884 | ||||
| 2022-11-03 | 2022-11-01 | 4 | Dunlop A. Sinclair | APLS | Common Stock | D | 60.8300 | -500 | -30 | 129,930 | ||||
| 2022-10-28 | 2022-10-26 | 4 | Brown Victoria L. | APLS | Common Stock | D | 58.4100 | -130 | -8 | 24,844 | ||||
| 2022-10-24 | 2022-10-20 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 58.0000 | -196 | -11 | 29,054 | ||||
| 2022-10-24 | 2022-10-20 | 4 | Chopas James George | APLS | Common Stock | D | 58.0000 | -130 | -8 | 18,451 | ||||
| 2022-10-17 | 2022-10-14 | 4 | Machiels Alec | APLS | Common Stock | D | 59.3100 | -1,250 | -74 | 263,774 | ||||
| 2022-10-17 | 2022-10-14 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 1,250 | 3 | 265,024 | ||||
| 2022-10-11 | 2022-10-10 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 57.5000 | -12,000 | -690 | 957,280 | ||||
| 2022-10-11 | 2022-10-10 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 18,500 | 49 | 969,280 | ||||
| 2022-10-05 | 2022-10-03 | 4 | Grossi Federico | APLS | Common Stock | D | 66.6900 | -2,500 | -167 | 102,384 | ||||
| 2022-10-05 | 2022-10-03 | 4 | Townsend Adam J. | APLS | Common Stock | D | 66.6900 | -5,000 | -333 | 42,907 | ||||
| 2022-10-05 | 2022-10-03 | 4 | Townsend Adam J. | APLS | Common Stock | D | 15.0900 | 5,000 | 75 | 47,907 | ||||
| 2022-09-16 | 2022-09-15 | 4 | Machiels Alec | APLS | Common Stock | D | 66.0000 | -1,250 | -82 | 263,774 | ||||
| 2022-09-16 | 2022-09-15 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 1,250 | 3 | 265,024 | ||||
| 2022-09-12 | 2022-09-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 63.9800 | -12,000 | -768 | 950,780 | ||||
| 2022-09-12 | 2022-09-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 18,500 | 49 | 962,780 | ||||
| 2022-09-08 | 2022-09-08 | 4 | Dunlop A. Sinclair Indirect Owner (Epidarex) | APLS | Common Stock | I | 65.0000 | -15,000 | -975 | 240,679 | ||||
| 2022-09-07 | 2022-09-06 | 4 | Townsend Adam J. | APLS | Common Stock | D | 60.3800 | -5,000 | -302 | 42,907 | ||||
| 2022-09-07 | 2022-09-06 | 4 | Townsend Adam J. | APLS | Common Stock | D | 15.0900 | 5,000 | 75 | 47,907 | ||||
| 2022-09-02 | 2022-09-01 | 4 | Grossi Federico | APLS | Common Stock | D | 60.3000 | -2,500 | -151 | 104,884 | ||||
| 2022-08-31 | 2022-08-30 | 4 | Chopas James George | APLS | Common Stock | D | 58.8400 | -558 | -33 | 18,581 | ||||
| 2022-08-26 | 2022-08-25 | 4 | Dunlop A. Sinclair | APLS | Common Stock | D | 13.1900 | 4,306 | 57 | 130,430 | ||||
| 2022-08-18 | 2022-08-17 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 69.5000 | -5,000 | -348 | 29,250 | ||||
| 2022-08-18 | 2022-08-17 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 15.5200 | 5,000 | 78 | 34,250 | ||||
| 2022-08-17 | 2022-08-16 | 4 | Dunlop A. Sinclair | APLS | Common Stock | D | 14.0000 | 25,394 | 356 | 126,124 | ||||
| 2022-08-16 | 2022-08-15 | 4 | Townsend Adam J. | APLS | Common Stock | D | 69.0000 | -12,500 | -862 | 42,907 | ||||
| 2022-08-16 | 2022-08-15 | 4 | Townsend Adam J. | APLS | Common Stock | D | 15.0900 | 12,500 | 189 | 55,407 | ||||
| 2022-08-16 | 2022-08-15 | 4 | Machiels Alec | APLS | Common Stock | D | 67.2100 | -1,250 | -84 | 263,774 | ||||
| 2022-08-16 | 2022-08-15 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 1,250 | 3 | 265,024 | ||||
| 2022-08-12 | 2022-08-11 | 4 | Dunlop A. Sinclair Indirect Owner (Epidarex) | APLS | Common Stock | I | 65.6300 | -30,000 | -1,969 | 255,679 | ||||
| 2022-08-12 | 2022-08-11 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 67.0000 | -5,000 | -335 | 29,250 | ||||
| 2022-08-12 | 2022-08-11 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 15.5200 | 5,000 | 78 | 34,250 | ||||
| 2022-08-12 | 2022-08-11 | 4 | Townsend Adam J. | APLS | Common Stock | D | 67.0000 | -12,500 | -838 | 42,907 | ||||
| 2022-08-12 | 2022-08-11 | 4 | Townsend Adam J. | APLS | Common Stock | D | 15.0900 | 12,500 | 189 | 55,407 | ||||
| 2022-08-09 | 2022-08-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 62.5000 | -12,000 | -750 | 944,280 | ||||
| 2022-08-09 | 2022-08-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 18,500 | 49 | 956,280 | ||||
| 2022-08-09 | 2022-08-08 | 4 | Townsend Adam J. | APLS | Common Stock | D | 65.0000 | -12,500 | -812 | 42,907 | ||||
| 2022-08-09 | 2022-08-08 | 4 | Townsend Adam J. | APLS | Common Stock | D | 15.0900 | 12,500 | 189 | 55,407 | ||||
| 2022-08-09 | 2022-08-08 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 64.5000 | -5,000 | -322 | 29,250 | ||||
| 2022-08-09 | 2022-08-08 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 15.5200 | 5,000 | 78 | 34,250 | ||||
| 2022-08-08 | 2022-08-04 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 62.0000 | -5,000 | -310 | 29,250 | ||||
| 2022-08-08 | 2022-08-04 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 59.5000 | -5,000 | -298 | 34,250 | ||||
| 2022-08-08 | 2022-08-04 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 15.5200 | 10,000 | 155 | 39,250 | ||||
| 2022-08-04 | 2022-08-03 | 4 | Townsend Adam J. | APLS | Common Stock | D | 15.0900 | 5,000 | 75 | 42,907 | ||||
| 2022-08-04 | 2022-08-03 | 4 | Townsend Adam J. | APLS | Common Stock | D | 56.4300 | -5,000 | -282 | 37,907 | ||||
| 2022-08-02 | 2022-08-01 | 4 | Grossi Federico | APLS | Common Stock | D | 55.9900 | -2,500 | -140 | 107,384 | ||||
| 2022-07-28 | 2022-07-27 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 57.0000 | -5,000 | -285 | 29,250 | ||||
| 2022-07-28 | 2022-07-27 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 15.5200 | 5,000 | 78 | 34,250 | ||||
| 2022-07-22 | 2022-07-21 | 4 | Dunlop A. Sinclair | APLS | Common Stock | D | 14.0000 | 9,606 | 134 | 100,730 | ||||
| 2022-07-21 | 2022-07-19 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 56.4200 | -5,000 | -282 | 29,250 | ||||
| 2022-07-21 | 2022-07-19 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 15.5200 | 5,000 | 78 | 34,250 | ||||
| 2022-07-18 | 2022-07-15 | 4 | Machiels Alec | APLS | Common Stock | D | 46.3300 | -1,250 | -58 | 263,774 | ||||
| 2022-07-18 | 2022-07-15 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 1,250 | 3 | 265,024 | ||||
| 2022-07-12 | 2022-07-11 | 4 | Townsend Adam J. | APLS | Common Stock | D | 48.4200 | -5,000 | -242 | 42,907 | ||||
| 2022-07-12 | 2022-07-11 | 4 | Townsend Adam J. | APLS | Common Stock | D | 15.0900 | 5,000 | 75 | 47,907 | ||||
| 2022-07-12 | 2022-04-21 | 4 | Townsend Adam J. | APLS | Common Stock | D | -1,875 | 42,138 | ||||||
| 2022-07-12 | 2022-07-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 47.9500 | -12,000 | -575 | 937,780 | ||||
| 2022-07-12 | 2022-07-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 6,500 | 17 | 949,780 | ||||
| 2022-07-12 | 2022-07-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 12,000 | 32 | 943,280 | ||||
| 2022-06-29 | 2022-06-27 | 4 | Dunlop A. Sinclair Indirect Owner (ECM) | APLS | Common Stock | I | 46.7881 | -1,341 | -63 | 1,341 | ||||
| 2022-06-24 | 2022-06-23 | 4 | Dunlop A. Sinclair Indirect Owner (Epidarex) | APLS | Common Stock | I | 45.0000 | -15,000 | -675 | 285,679 | ||||
| 2022-06-23 | 2022-06-22 | 4 | Watson David O. | APLS | Common Stock | D | 44.5140 | -10,000 | -445 | 115,569 | ||||
| 2022-06-22 | 2022-06-17 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 33,005 | 88 | 931,280 | ||||
| 2022-06-22 | 2022-06-17 | 4 | Brown Victoria L. | APLS | Common Stock | D | 45.0000 | -2,698 | -121 | 24,974 | ||||
| 2022-06-21 | 2022-06-16 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 41.7850 | -10,000 | -418 | 29,250 | ||||
| 2022-06-21 | 2022-06-16 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 13.8500 | 10,000 | 138 | 39,250 | ||||
| 2022-06-17 | 2022-06-15 | 4 | Machiels Alec | APLS | Common Stock | D | 39.2900 | -1,250 | -49 | 263,774 | ||||
| 2022-06-17 | 2022-06-15 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 1,250 | 3 | 265,024 | ||||
| 2022-06-09 | 2022-06-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 6,500 | 17 | 898,275 | ||||
| 2022-06-09 | 2022-06-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 44.0900 | -12,000 | -529 | 891,775 | ||||
| 2022-06-09 | 2022-06-08 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 12,000 | 32 | 903,775 | ||||
| 2022-06-02 | 2022-06-01 | 4 | Grossi Federico | APLS | Common Stock | D | 41.7800 | -2,500 | -104 | 109,561 | ||||
| 2022-05-31 | 2022-05-27 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 43.0000 | -10,000 | -430 | 40,358 | ||||
| 2022-05-31 | 2022-04-21 | 4 | SCHEIBLER LUKAS | APLS | Stock Option (Right to Buy) | D | 44.90 | -11,250 | 0 | |||||
| 2022-05-31 | 2022-04-21 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | -1,875 | 50,358 | ||||||
| 2022-05-17 | 2022-05-16 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -1,250 | 122,279 | |||||
| 2022-05-17 | 2022-05-16 | 4 | Machiels Alec | APLS | Common Stock | D | 39.1800 | -1,250 | -49 | 263,774 | ||||
| 2022-05-17 | 2022-05-16 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 1,250 | 3 | 265,024 | ||||
| 2022-05-03 | 2022-05-02 | 4 | Grossi Federico | APLS | Common Stock | D | 43.5600 | -2,500 | -109 | 112,061 | ||||
| 2022-05-03 | 2022-04-21 | 4 | Grossi Federico | APLS | Stock Option (Right to Buy) | D | 44.90 | -11,250 | 0 | |||||
| 2022-05-03 | 2022-04-21 | 4 | Grossi Federico | APLS | Common Stock | D | -1,875 | 114,561 | ||||||
| 2022-05-02 | 2022-04-29 | 4 | Deschatelets Pascal | APLS | Stock Option (Right to Buy) | D | 2.67 | -4,000 | 364,999 | |||||
| 2022-05-02 | 2022-04-29 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 44.4300 | -4,000 | -178 | 891,775 | ||||
| 2022-05-02 | 2022-04-29 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 4,000 | 11 | 895,775 | ||||
| 2022-05-02 | 2022-04-21 | 4 | Deschatelets Pascal | APLS | Stock Option (Right to Buy) | D | 44.90 | -11,250 | 0 | |||||
| 2022-05-02 | 2022-04-21 | 4 | Deschatelets Pascal | APLS | Common Stock | D | -1,875 | 891,775 | ||||||
| 2022-04-27 | 2022-04-25 | 4 | Watson David O. | APLS | Common Stock | D | 50.0000 | -5,000 | -250 | 125,569 | ||||
| 2022-04-27 | 2022-04-21 | 4 | Watson David O. | APLS | Stock Option (Right to Buy) | D | 44.90 | -11,250 | 0 | |||||
| 2022-04-27 | 2022-04-21 | 4 | Watson David O. | APLS | Common Stock | D | -1,875 | 130,569 | ||||||
| 2022-04-25 | 2022-04-22 | 4 | Dunlop A. Sinclair | APLS | Stock Option (Right to Buy) | D | 14.00 | -20,000 | 35,000 | |||||
| 2022-04-25 | 2022-04-22 | 4 | Dunlop A. Sinclair | APLS | Common Stock | D | 14.0000 | 20,000 | 280 | 91,124 | ||||
| 2022-04-22 | 2022-04-20 | 4 | DeLong Mark Jeffrey | APLS | Stock Option (Right to Buy) | D | 15.52 | -7,000 | 35,000 | |||||
| 2022-04-22 | 2022-04-20 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 52.5300 | -7,000 | -368 | 28,481 | ||||
| 2022-04-22 | 2022-04-20 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 15.5200 | 7,000 | 109 | 35,481 | ||||
| 2022-04-18 | 2022-04-14 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -1,250 | 123,529 | |||||
| 2022-04-18 | 2022-04-14 | 4 | Machiels Alec | APLS | Common Stock | D | 50.9000 | -1,250 | -64 | 263,774 | ||||
| 2022-04-18 | 2022-04-14 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 1,250 | 3 | 265,024 | ||||
| 2022-04-06 | 2022-04-05 | 4 | SCHEIBLER LUKAS | APLS | Stock Option (Right to Buy) | D | 13.85 | -609 | 49,391 | |||||
| 2022-04-06 | 2022-04-05 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 60.0870 | -609 | -37 | 52,233 | ||||
| 2022-04-06 | 2022-04-05 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 13.8500 | 609 | 8 | 52,842 | ||||
| 2022-04-05 | 2022-04-04 | 4 | SCHEIBLER LUKAS | APLS | Stock Option (Right to Buy) | D | 13.85 | -3,504 | 50,000 | |||||
| 2022-04-05 | 2022-04-04 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 57.8050 | -1,249 | -72 | 52,233 | ||||
| 2022-04-05 | 2022-04-04 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 56.8640 | -1,437 | -82 | 53,482 | ||||
| 2022-04-05 | 2022-04-04 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 55.8400 | -818 | -46 | 54,919 | ||||
| 2022-04-05 | 2022-04-04 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 13.8500 | 3,504 | 49 | 55,737 | ||||
| 2022-04-04 | 2022-04-01 | 4 | SCHEIBLER LUKAS | APLS | Stock Option (Right to Buy) | D | 13.85 | -11,496 | 53,504 | |||||
| 2022-04-04 | 2022-04-01 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 55.0500 | -11,496 | -633 | 52,233 | ||||
| 2022-04-04 | 2022-04-01 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 13.8500 | 11,496 | 159 | 63,729 | ||||
| 2022-03-29 | 2022-03-25 | 4 | Brown Victoria L. | APLS | Common Stock | D | 49.2800 | -82 | -4 | 28,325 | ||||
| 2022-03-17 | 2022-03-15 | 4 | Machiels Alec | APLS | Stock option (right to buy) | D | 2.67 | -1,250 | 124,779 | |||||
| 2022-03-17 | 2022-03-15 | 4 | Machiels Alec | APLS | Common Stock | D | 39.5700 | -1,250 | -49 | 259,544 | ||||
| 2022-03-17 | 2022-03-15 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 1,250 | 3 | 260,794 | ||||
| 2022-03-17 | 2022-03-15 | 4 | Grossi Federico | APLS | Stock Option (Right to Buy) | D | 4.31 | -7,000 | 50,723 | |||||
| 2022-03-17 | 2022-03-15 | 4 | Grossi Federico | APLS | Common Stock | D | 39.5700 | -375 | -15 | 116,436 | ||||
| 2022-03-17 | 2022-03-15 | 4 | Grossi Federico | APLS | Common Stock | D | 4.3100 | 7,000 | 30 | 116,811 | ||||
| 2022-03-02 | 2022-03-01 | 4 | Grossi Federico | APLS | Common Stock | D | 43.5300 | -375 | -16 | 109,811 | ||||
| 2022-02-24 | 2022-02-23 | 4 | Grossi Federico | APLS | Stock Option (Right to Buy) | D | 4.31 | -4,100 | 57,723 | |||||
| 2022-02-24 | 2022-02-23 | 4 | Grossi Federico | APLS | Common Stock | D | 4.3100 | 4,100 | 18 | 110,186 | ||||
| 2022-02-16 | 2022-02-15 | 4 | Grossi Federico | APLS | Common Stock | D | 45.4300 | -375 | -17 | 106,086 | ||||
| 2022-02-16 | 2022-02-15 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -1,250 | 126,029 | |||||
| 2022-02-16 | 2022-02-15 | 4 | Machiels Alec | APLS | Common Stock | D | 45.4300 | -1,250 | -57 | 673,774 | ||||
| 2022-02-16 | 2022-02-15 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 1,250 | 3 | 675,024 | ||||
| 2022-02-15 | 2022-02-14 | 4 | Grossi Federico | APLS | Stock Option (Right to Buy) | D | 4.31 | -3,600 | 61,823 | |||||
| 2022-02-15 | 2022-02-14 | 4 | Grossi Federico | APLS | Common Stock | D | 4.3100 | 3,600 | 16 | 106,461 | ||||
| 2022-02-15 | 2022-02-14 | 4 | SCHEIBLER LUKAS | APLS | Stock Option (Right to Buy) | D | 26.73 | -720 | 133,777 | |||||
| 2022-02-15 | 2022-02-14 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 26.7300 | 720 | 19 | 52,233 | ||||
| 2022-02-14 | 2022-02-10 | 4 | Watson David O. | APLS | Common Stock | D | 47.1200 | -491 | -23 | 132,444 | ||||
| 2022-02-14 | 2022-02-11 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 46.8000 | -1,666 | -78 | 51,513 | ||||
| 2022-02-14 | 2022-02-10 | 4 | Francois Cedric | APLS | Common Stock | D | 47.1200 | -2,523 | -119 | 955,940 | ||||
| 2022-02-14 | 2022-02-10 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 47.1200 | -875 | -41 | 103,403 | ||||
| 2022-02-14 | 2022-02-10 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 47.1200 | -1,057 | -50 | 893,650 | ||||
| 2022-02-14 | 2022-02-10 | 4 | Townsend Adam J. | APLS | Common Stock | D | 47.1200 | -895 | -42 | 44,013 | ||||
| 2022-02-14 | 2022-02-10 | 4 | SCHEIBLER LUKAS | APLS | Stock Option (Right to Buy) | D | 13.85 | -10,000 | 65,000 | |||||
| 2022-02-14 | 2022-02-10 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 50.0000 | -10,000 | -500 | 53,179 | ||||
| 2022-02-14 | 2022-02-10 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 13.8500 | 10,000 | 138 | 63,179 | ||||
| 2022-02-14 | 2022-02-10 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 47.1200 | -678 | -32 | 53,179 | ||||
| 2022-02-14 | 2022-02-10 | 4 | Grossi Federico | APLS | Common Stock | D | 47.1200 | -705 | -33 | 102,861 | ||||
| 2022-02-14 | 2022-02-10 | 4 | Brown Victoria L. | APLS | Common Stock | D | 47.1200 | -175 | -8 | 28,407 | ||||
| 2022-02-14 | 2022-02-10 | 4 | DeLong Mark Jeffrey | APLS | Stock Option (Right to Buy) | D | 47.12 | 6,952 | 6,952 | |||||
| 2022-02-14 | 2022-02-10 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 4,901 | 28,481 | ||||||
| 2022-02-14 | 2022-02-10 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 47.1200 | -271 | -13 | 23,580 | ||||
| 2022-02-10 | 2021-12-08 | 5 | Watson David O. | APLS | Common Stock | D | -3,333 | 3,333 | ||||||
| 2022-02-10 | 2021-07-22 | 5 | Machiels Alec | APLS | Common Stock | D | -160,000 | 259,544 | ||||||
| 2022-02-10 | 2021-06-16 | 5 | Francois Cedric | APLS | Common Stock | D | -80,000 | 854,243 | ||||||
| 2022-02-10 | 2022-02-08 | 4 | SCHEIBLER LUKAS | APLS | Stock Option (Right to Buy) | D | 13.85 | -10,000 | 75,000 | |||||
| 2022-02-10 | 2022-02-08 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 45.0000 | -10,000 | -450 | 53,857 | ||||
| 2022-02-10 | 2022-02-08 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 13.8500 | 10,000 | 138 | 63,857 | ||||
| 2022-02-07 | 2022-01-21 | 4/A | DeLong Mark Jeffrey | APLS | Stock Option (right to buy) | D | 35.46 | 19,735 | 19,735 | |||||
| 2022-02-07 | 2022-01-21 | 4/A | DeLong Mark Jeffrey | APLS | Common Stock | D | 13,913 | 24,285 | ||||||
| 2022-02-07 | 2022-01-21 | 4/A | Chopas James George | APLS | Stock Option (right to buy) | D | 35.46 | 15,116 | 15,116 | |||||
| 2022-02-07 | 2022-01-21 | 4/A | Chopas James George | APLS | Common Stock | D | 10,657 | 19,139 | ||||||
| 2022-02-02 | 2022-02-01 | 4 | Grossi Federico | APLS | Common Stock | D | 40.5800 | -375 | -15 | 103,566 | ||||
| 2022-02-01 | 2022-01-28 | 4 | Brown Victoria L. | APLS | Common Stock | D | 38.5900 | -434 | -17 | 28,582 | ||||
| 2022-02-01 | 2022-01-28 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 38.5900 | -434 | -17 | 20,530 | ||||
| 2022-02-01 | 2022-01-28 | 4 | Grossi Federico | APLS | Common Stock | D | 38.5900 | -650 | -25 | 103,941 | ||||
| 2022-02-01 | 2022-01-28 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 38.5900 | -434 | -17 | 32,989 | ||||
| 2022-02-01 | 2022-01-28 | 4 | Nicholson Nur | APLS | Common Stock | D | 38.5900 | -650 | -25 | 35,555 | ||||
| 2022-02-01 | 2022-01-28 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 38.5900 | -650 | -25 | 104,278 | ||||
| 2022-02-01 | 2022-01-28 | 4 | Watson David O. | APLS | Common Stock | D | 38.5900 | -650 | -25 | 132,935 | ||||
| 2022-02-01 | 2022-01-28 | 4 | Townsend Adam J. | APLS | Common Stock | D | 38.5900 | -800 | -31 | 44,908 | ||||
| 2022-02-01 | 2022-01-28 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 38.5900 | -931 | -36 | 894,707 | ||||
| 2022-02-01 | 2022-01-28 | 4 | Lewis Karen | APLS | Common Stock | D | 38.5900 | -434 | -17 | 23,474 | ||||
| 2022-02-01 | 2022-01-28 | 4 | Francois Cedric | APLS | Common Stock | D | 38.5900 | -2,024 | -78 | 1,338,463 | ||||
| 2022-02-01 | 2022-01-31 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 38.4700 | -1,233 | -47 | 53,857 | ||||
| 2022-02-01 | 2022-01-28 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 38.5900 | -642 | -25 | 55,090 | ||||
| 2022-01-25 | 2022-01-21 | 4 | Francois Cedric | APLS | Stock Option (Right to Buy) | D | 35.46 | 150,672 | 150,672 | |||||
| 2022-01-25 | 2022-01-21 | 4 | Francois Cedric | APLS | Common Stock | D | 106,244 | 1,340,487 | ||||||
| 2022-01-25 | 2022-01-21 | 4 | SCHEIBLER LUKAS | APLS | Stock Option (Right to Buy) | D | 35.46 | 36,951 | 36,951 | |||||
| 2022-01-25 | 2022-01-21 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 26,051 | 55,732 | ||||||
| 2022-01-25 | 2022-01-21 | 4 | Sullivan Timothy Eugene | APLS | Stock Option (Right to Buy) | D | 35.46 | 43,670 | 43,670 | |||||
| 2022-01-25 | 2022-01-21 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 30,787 | 104,928 | ||||||
| 2022-01-25 | 2022-01-21 | 4 | Townsend Adam J. | APLS | Stock Option (Right to Buy) | D | 35.46 | 36,951 | 36,951 | |||||
| 2022-01-25 | 2022-01-21 | 4 | Townsend Adam J. | APLS | Common Stock | D | 26,051 | 45,708 | ||||||
| 2022-01-25 | 2022-01-21 | 4 | Deschatelets Pascal | APLS | Stock Option (Right to Buy) | D | 35.46 | 36,951 | 36,951 | |||||
| 2022-01-25 | 2022-01-21 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 26,051 | 895,638 | ||||||
| 2022-01-25 | 2022-01-21 | 4 | Grossi Federico | APLS | Stock Option (Right to Buy) | D | 35.46 | 36,951 | 36,951 | |||||
| 2022-01-25 | 2022-01-21 | 4 | Grossi Federico | APLS | Common Stock | D | 26,051 | 104,591 | ||||||
| 2022-01-25 | 2022-01-21 | 4 | Nicholson Nur | APLS | Stock Option (Right to Buy) | D | 35.46 | 36,951 | 36,951 | |||||
| 2022-01-25 | 2022-01-21 | 4 | Nicholson Nur | APLS | Common Stock | D | 26,051 | 36,205 | ||||||
| 2022-01-25 | 2022-01-21 | 4 | Eisele Jeffrey | APLS | Stock Option (Right to Buy) | D | 35.46 | 36,951 | 36,951 | |||||
| 2022-01-25 | 2022-01-21 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 26,051 | 33,423 | ||||||
| 2022-01-25 | 2022-01-21 | 4 | Watson David O. | APLS | Stock Option (Right to Buy) | D | 35.46 | 36,951 | 36,951 | |||||
| 2022-01-25 | 2022-01-21 | 4 | Watson David O. | APLS | Common Stock | D | 26,051 | 133,585 | ||||||
| 2022-01-25 | 2022-01-21 | 4 | Lewis Karen | APLS | Stock Option (Right to Buy) | D | 35.46 | 24,774 | 24,774 | |||||
| 2022-01-25 | 2022-01-21 | 4 | Lewis Karen | APLS | Common Stock | D | 17,466 | 23,908 | ||||||
| 2022-01-25 | 2022-01-21 | 4 | Brown Victoria L. | APLS | Stock Option (Right to Buy) | D | 35.46 | 24,774 | 24,774 | |||||
| 2022-01-25 | 2022-01-21 | 4 | Brown Victoria L. | APLS | Common Stock | D | 17,466 | 29,016 | ||||||
| 2022-01-25 | 2022-01-21 | 4 | DeLong Mark Jeffrey | APLS | Stock Option (Right to Buy) | D | 35.46 | 15,024 | 15,024 | |||||
| 2022-01-25 | 2022-01-21 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 10,592 | 20,964 | ||||||
| 2022-01-25 | 2022-01-21 | 4 | Chopas James George | APLS | Stock Option (Right to Buy) | D | 35.46 | 9,892 | 9,892 | |||||
| 2022-01-25 | 2022-01-21 | 4 | Chopas James George | APLS | Common Stock | D | 6,974 | 15,456 | ||||||
| 2022-01-24 | 2022-01-21 | 4 | SCHEIBLER LUKAS | APLS | Stock Option (Right to Buy) | D | 26.73 | -3,021 | 134,497 | |||||
| 2022-01-24 | 2022-01-21 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 26.7300 | 3,021 | 81 | 29,681 | ||||
| 2022-01-19 | 2022-01-14 | 4 | Machiels Alec | APLS | Stock Option(Right to Buy) | D | 2.67 | -1,250 | 27,279 | |||||
| 2022-01-19 | 2022-01-14 | 4 | Machiels Alec | APLS | Common Stock | D | 40.5600 | -1,250 | -51 | 673,774 | ||||
| 2022-01-19 | 2022-01-14 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 1,250 | 3 | 675,024 | ||||
| 2022-01-19 | 2022-01-14 | 4 | Grossi Federico | APLS | Stock Option (Right to Buy) | D | 4.31 | -3,400 | 65,423 | |||||
| 2022-01-19 | 2022-01-14 | 4 | Grossi Federico | APLS | Common Stock | D | 40.5600 | -375 | -15 | 78,540 | ||||
| 2022-01-19 | 2022-01-14 | 4 | Grossi Federico | APLS | Common Stock | D | 4.3100 | 3,400 | 15 | 78,915 | ||||
| 2022-01-14 | 2022-01-12 | 4 | Grossi Federico | APLS | Stock Option (Right to Buy) | D | 4.31 | -1,500 | 68,823 | |||||
| 2022-01-14 | 2022-01-12 | 4 | Grossi Federico | APLS | Stock Option (Right to Buy) | D | 3.76 | -3,661 | 0 | |||||
| 2022-01-14 | 2022-01-12 | 4 | Grossi Federico | APLS | Common Stock | D | 4.3100 | 1,500 | 6 | 75,515 | ||||
| 2022-01-14 | 2022-01-12 | 4 | Grossi Federico | APLS | Common Stock | D | 3.7600 | 3,661 | 14 | 74,015 | ||||
| 2022-01-04 | 2022-01-01 | 4 | Chan Gerald | APLS | Stock Option (Right to Buy) | D | 47.28 | 8,554 | 8,554 | |||||
| 2022-01-04 | 2022-01-01 | 4 | Chan Gerald | APLS | Common Stock | D | 4,230 | 4,230 | ||||||
| 2022-01-04 | 2022-01-01 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 47.28 | 8,554 | 8,554 | |||||
| 2022-01-04 | 2022-01-01 | 4 | Machiels Alec | APLS | Common Stock | D | 4,230 | 673,774 | ||||||
| 2022-01-04 | 2022-01-01 | 4 | FONTEYNE PAUL R. | APLS | Stock Option (Right to Buy) | D | 47.28 | 8,554 | 8,554 | |||||
| 2022-01-04 | 2022-01-01 | 4 | FONTEYNE PAUL R. | APLS | Common Stock | D | 4,230 | 9,230 | ||||||
| 2022-01-04 | 2022-01-01 | 4 | O'Brien Stephanie Monaghan | APLS | Stock Option (Right to Buy) | D | 47.28 | 8,554 | 8,554 | |||||
| 2022-01-04 | 2022-01-01 | 4 | O'Brien Stephanie Monaghan | APLS | Common Stock | D | 4,230 | 4,230 | ||||||
| 2022-01-04 | 2022-01-01 | 4 | Dunlop A. Sinclair | APLS | Stock Option (Right to Buy) | D | 47.28 | 8,554 | 8,554 | |||||
| 2022-01-04 | 2022-01-01 | 4 | Dunlop A. Sinclair | APLS | Common Stock | D | 4,230 | 71,124 | ||||||
| 2022-01-04 | 2022-01-03 | 4 | Grossi Federico | APLS | Common Stock | D | 47.3100 | -375 | -18 | 70,354 | ||||
| 2021-12-28 | 2021-12-27 | 4 | Watson David O. | APLS | Common Stock | D | 48.5000 | -1,200 | -58 | 107,534 | ||||
| 2021-12-23 | 2021-12-22 | 4 | Watson David O. | APLS | Stock Option (Right to Buy) | D | 14.95 | -5,397 | 14,888 | |||||
| 2021-12-23 | 2021-12-22 | 4 | Watson David O. | APLS | Stock Option (Right to Buy) | D | 14.95 | -4,715 | 20,285 | |||||
| 2021-12-23 | 2021-12-22 | 4 | Watson David O. | APLS | Stock Option (Right to Buy) | D | 13.85 | -4,826 | 11,667 | |||||
| 2021-12-23 | 2021-12-22 | 4 | Watson David O. | APLS | Stock Option (Right to Buy) | D | 13.85 | -5,174 | 16,493 | |||||
| 2021-12-23 | 2021-12-22 | 4 | Watson David O. | APLS | Common Stock | D | 48.5770 | -300 | -15 | 108,734 | ||||
| 2021-12-23 | 2021-12-22 | 4 | Watson David O. | APLS | Common Stock | D | 47.8550 | -5,097 | -244 | 109,034 | ||||
| 2021-12-23 | 2021-12-22 | 4 | Watson David O. | APLS | Common Stock | D | 14.9500 | 5,397 | 81 | 114,131 | ||||
| 2021-12-23 | 2021-12-22 | 4 | Watson David O. | APLS | Common Stock | D | 14.9500 | 4,715 | 70 | 108,734 | ||||
| 2021-12-23 | 2021-12-22 | 4 | Watson David O. | APLS | Common Stock | D | 47.7160 | -5,174 | -247 | 104,019 | ||||
| 2021-12-23 | 2021-12-22 | 4 | Watson David O. | APLS | Common Stock | D | 13.8500 | 4,826 | 67 | 109,193 | ||||
| 2021-12-23 | 2021-12-22 | 4 | Watson David O. | APLS | Common Stock | D | 13.8500 | 5,174 | 72 | 104,367 | ||||
| 2021-12-23 | 2021-12-22 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 47.8200 | -89 | -4 | 7,372 | ||||
| 2021-12-17 | 2021-12-15 | 4 | Grossi Federico | APLS | Common Stock | D | 42.8800 | -375 | -16 | 70,729 | ||||
| 2021-12-17 | 2021-12-15 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -3,000 | 128,529 | |||||
| 2021-12-17 | 2021-12-15 | 4 | Machiels Alec | APLS | Common Stock | D | 42.8800 | -3,000 | -129 | 669,544 | ||||
| 2021-12-17 | 2021-12-15 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 3,000 | 8 | 672,544 | ||||
| 2021-12-09 | 2021-12-08 | 4 | Grossi Federico | APLS | Stock Option (Right to Buy) | D | 3.76 | -7,000 | 3,661 | |||||
| 2021-12-09 | 2021-12-08 | 4 | Grossi Federico | APLS | Common Stock | D | 3.7600 | 7,000 | 26 | 71,104 | ||||
| 2021-12-03 | 2021-12-01 | 4 | Grossi Federico | APLS | Common Stock | D | 42.4000 | -375 | -16 | 64,104 | ||||
| 2021-11-18 | 2021-11-18 | 4 | Morningside Venture Investments Ltd | APLS | Common Stock | D | 40.0000 | 250,000 | 10,000 | 12,806,342 | ||||
| 2021-11-17 | 2021-11-15 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -3,000 | 131,529 | |||||
| 2021-11-17 | 2021-11-15 | 4 | Machiels Alec | APLS | Common Stock | D | 43.5000 | -3,000 | -130 | 669,544 | ||||
| 2021-11-17 | 2021-11-15 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 3,000 | 8 | 672,544 | ||||
| 2021-11-17 | 2021-11-04 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -3,000 | 134,529 | |||||
| 2021-11-17 | 2021-11-04 | 4 | Machiels Alec | APLS | Common Stock | D | 35.0000 | -3,000 | -105 | 669,544 | ||||
| 2021-11-17 | 2021-11-04 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 3,000 | 8 | 672,544 | ||||
| 2021-11-17 | 2021-11-15 | 4 | Grossi Federico | APLS | Common Stock | D | 43.5000 | -625 | -27 | 64,479 | ||||
| 2021-11-02 | 2021-11-01 | 4 | Grossi Federico | APLS | Common Stock | D | 30.7000 | -625 | -19 | 64,805 | ||||
| 2021-10-27 | 2021-10-20 | 4 | Chopas James George | APLS | Common Stock | D | 882 | 8,482 | ||||||
| 2021-10-27 | 2021-10-20 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 882 | 10,372 | ||||||
| 2021-10-27 | 2021-10-26 | 4 | Brown Victoria L. | APLS | Common Stock | D | 882 | 11,422 | ||||||
| 2021-10-15 | 2021-10-14 | 4 | Grossi Federico | APLS | Common Stock | D | 34.5700 | -750 | -26 | 65,430 | ||||
| 2021-10-05 | 2021-10-01 | 4 | Grossi Federico | APLS | Common Stock | D | 33.2600 | -750 | -25 | 66,180 | ||||
| 2021-09-29 | 2021-09-28 | 4 | Grossi Federico | APLS | Stock Option (Right to Buy) | D | 3.76 | -4,000 | 10,661 | |||||
| 2021-09-29 | 2021-09-28 | 4 | Grossi Federico | APLS | Common Stock | D | 3.7600 | 4,000 | 15 | 66,930 | ||||
| 2021-09-13 | 2021-09-10 | 4 | Dunlop A. Sinclair | APLS | Stock Option (Right to Buy) | D | 14.00 | -6,894 | 55,000 | |||||
| 2021-09-13 | 2021-09-10 | 4 | Dunlop A. Sinclair | APLS | Common Stock | D | 14.0000 | 6,894 | 97 | 66,894 | ||||
| 2021-09-13 | 2021-09-10 | 4 | Watson David O. | APLS | Stock Option (Right to Buy) | D | 4.31 | -954 | 0 | |||||
| 2021-09-13 | 2021-09-10 | 4 | Watson David O. | APLS | Common Stock | D | 4.3100 | 954 | 4 | 99,193 | ||||
| 2021-09-01 | 2021-08-30 | 4 | Chopas James George | APLS | Stock Option (right to buy) | D | 65.41 | 21,750 | 21,750 | |||||
| 2021-09-01 | 2021-08-30 | 4 | Chopas James George | APLS | Common Stock | D | 7,600 | 7,600 | ||||||
| 2021-08-17 | 2021-08-16 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -2,500 | 137,529 | |||||
| 2021-08-17 | 2021-08-16 | 4 | Machiels Alec | APLS | Common Stock | D | 56.9500 | -2,500 | -142 | 669,544 | ||||
| 2021-08-17 | 2021-08-16 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 2,500 | 7 | 672,044 | ||||
| 2021-08-03 | 2021-08-02 | 4 | Grossi Federico | APLS | Common Stock | D | 63.9900 | -250 | -16 | 62,930 | ||||
| 2021-08-03 | 2021-08-02 | 4 | Perry Nicole D | APLS | Stock Option (Right to Buy) | D | 3.76 | -1,000 | 6,161 | |||||
| 2021-08-03 | 2021-08-02 | 4 | Perry Nicole D | APLS | Common Stock | D | 63.9900 | -1,000 | -64 | 4,847 | ||||
| 2021-08-03 | 2021-08-02 | 4 | Perry Nicole D | APLS | Common Stock | D | 3.7600 | 1,000 | 4 | 5,847 | ||||
| 2021-07-22 | 2021-07-21 | 4 | DeLong Mark Jeffrey | APLS | Stock Option (Right to Buy) | D | 15.52 | -1,000 | 42,000 | |||||
| 2021-07-22 | 2021-07-21 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 65.0000 | -1,000 | -65 | 9,490 | ||||
| 2021-07-22 | 2021-07-21 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 15.5200 | 1,000 | 16 | 10,490 | ||||
| 2021-07-22 | 2021-07-21 | 4 | Francois Cedric | APLS | Stock Option (Right to Buy) | D | 4.31 | -14,410 | 375,538 | |||||
| 2021-07-22 | 2021-07-21 | 4 | Francois Cedric | APLS | Common Stock | D | 4.3100 | 14,410 | 62 | 1,234,243 | ||||
| 2021-07-16 | 2021-07-15 | 4 | DeLong Mark Jeffrey | APLS | Stock Option (Right to Buy) | D | 15.52 | -1,000 | 43,000 | |||||
| 2021-07-16 | 2021-07-15 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 62.3000 | -1,000 | -62 | 9,490 | ||||
| 2021-07-16 | 2021-07-15 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 15.5200 | 1,000 | 16 | 10,490 | ||||
| 2021-07-16 | 2021-07-15 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -2,500 | 140,029 | |||||
| 2021-07-16 | 2021-07-15 | 4 | Machiels Alec | APLS | Common Stock | D | 62.3000 | -2,500 | -156 | 669,544 | ||||
| 2021-07-16 | 2021-07-15 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 2,500 | 7 | 672,044 | ||||
| 2021-07-15 | 2021-07-14 | 4 | Grossi Federico | APLS | Common Stock | D | 64.6800 | -500 | -32 | 63,180 | ||||
| 2021-07-09 | 2021-07-08 | 4 | Grossi Federico | APLS | Common Stock | D | 65.6800 | -250 | -16 | 63,680 | ||||
| 2021-07-02 | 2021-07-01 | 4 | Perry Nicole D | APLS | Stock Option (Right to Buy) | D | 3.76 | -1,000 | 7,161 | |||||
| 2021-07-02 | 2021-07-01 | 4 | Perry Nicole D | APLS | Common Stock | D | 64.0000 | -1,000 | -64 | 4,847 | ||||
| 2021-07-02 | 2021-07-01 | 4 | Perry Nicole D | APLS | Common Stock | D | 3.7600 | 1,000 | 4 | 5,847 | ||||
| 2021-06-29 | 2021-06-28 | 4 | Grossi Federico | APLS | Stock Option (Right to Buy) | D | 3.76 | -9,000 | 14,661 | |||||
| 2021-06-29 | 2021-06-28 | 4 | Grossi Federico | APLS | Common Stock | D | 3.7600 | 9,000 | 34 | 63,930 | ||||
| 2021-06-25 | 2021-06-24 | 4 | Deschatelets Pascal | APLS | Stock Option (Right to Buy) | D | 2.67 | -6,250 | 368,999 | |||||
| 2021-06-25 | 2021-06-24 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 65.6100 | -6,250 | -410 | 869,587 | ||||
| 2021-06-25 | 2021-06-24 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 6,250 | 17 | 875,837 | ||||
| 2021-06-22 | 2021-06-21 | 4 | Watson David O. | APLS | Stock Option (Right to Buy) | D | 4.31 | -489 | 954 | |||||
| 2021-06-22 | 2021-06-21 | 4 | Watson David O. | APLS | Common Stock | D | 4.3100 | 489 | 2 | 98,239 | ||||
| 2021-06-16 | 2021-06-15 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -2,500 | 142,529 | |||||
| 2021-06-16 | 2021-06-15 | 4 | Machiels Alec | APLS | Common Stock | D | 64.8300 | -2,500 | -162 | 669,544 | ||||
| 2021-06-16 | 2021-06-15 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 2,500 | 7 | 672,044 | ||||
| 2021-06-16 | 2021-06-15 | 4 | DeLong Mark Jeffrey | APLS | Stock Option (Right to Buy) | D | 15.52 | -4,000 | 44,000 | |||||
| 2021-06-16 | 2021-06-15 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 64.9575 | -4,000 | -260 | 9,490 | ||||
| 2021-06-16 | 2021-06-15 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 15.5200 | 4,000 | 62 | 13,490 | ||||
| 2021-06-15 | 2021-06-11 | 4 | Perry Nicole D | APLS | Stock Option (Right to Buy) | D | 3.20 | -1,000 | 34,161 | |||||
| 2021-06-15 | 2021-06-11 | 4 | Perry Nicole D | APLS | Common Stock | D | 61.5550 | -1,000 | -62 | 4,847 | ||||
| 2021-06-15 | 2021-06-11 | 4 | Perry Nicole D | APLS | Common Stock | D | 3.2000 | 1,000 | 3 | 5,847 | ||||
| 2021-06-15 | 2021-06-14 | 4 | Grossi Federico | APLS | Common Stock | D | 61.8400 | -500 | -31 | 54,930 | ||||
| 2021-06-11 | 2021-06-10 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 60.0000 | -3,417 | -205 | 26,651 | ||||
| 2021-06-09 | 2021-06-08 | 4 | Sullivan Timothy Eugene | APLS | Stock Option (Right to Buy) | D | 10.03 | -39,880 | 358,619 | |||||
| 2021-06-09 | 2021-06-08 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 10.0300 | 39,880 | 400 | 74,141 | ||||
| 2021-06-02 | 2021-06-01 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | 2,682 | 303,361 | ||||||
| 2021-06-02 | 2021-06-01 | 4 | Dunlop A. Sinclair | APLS | Common Stock | D | 13,108 | 73,108 | ||||||
| 2021-06-02 | 2021-06-01 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | -31,855 | 0 | ||||||
| 2021-06-02 | 2021-06-01 | 4 | Perry Nicole D | APLS | Stock Option (Right to Buy) | D | 3.76 | -1,000 | 8,161 | |||||
| 2021-06-02 | 2021-06-01 | 4 | Perry Nicole D | APLS | Common Stock | D | 56.4000 | -1,000 | -56 | 4,847 | ||||
| 2021-06-02 | 2021-06-01 | 4 | Perry Nicole D | APLS | Common Stock | D | 3.7600 | 1,000 | 4 | 5,847 | ||||
| 2021-06-01 | 2021-05-28 | 4 | Watson David O. | APLS | Stock Option (Right to Buy) | D | 4.31 | -489 | 1,443 | |||||
| 2021-06-01 | 2021-05-28 | 4 | Watson David O. | APLS | Common Stock | D | 4.3100 | 489 | 2 | 97,750 | ||||
| 2021-05-25 | 2021-05-24 | 4 | Deschatelets Pascal | APLS | Stock Option (Right to Buy) | D | 2.67 | -6,250 | 375,249 | |||||
| 2021-05-25 | 2021-05-24 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 47.4000 | -6,250 | -296 | 869,587 | ||||
| 2021-05-25 | 2021-05-24 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 6,250 | 17 | 875,837 | ||||
| 2021-05-20 | 2021-05-20 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | 48.1000 | -5,773 | -278 | 31,855 | ||||
| 2021-05-20 | 2021-05-19 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | 50.0000 | -7,612 | -381 | 300,679 | ||||
| 2021-05-20 | 2021-05-18 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | 54.0200 | -800 | -43 | 308,291 | ||||
| 2021-05-20 | 2021-05-18 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | 53.5000 | -10,388 | -556 | 309,091 | ||||
| 2021-05-20 | 2021-05-18 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | 52.0100 | -1,200 | -62 | 319,479 | ||||
| 2021-05-20 | 2021-05-18 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | 54.5700 | -22,318 | -1,218 | 37,628 | ||||
| 2021-05-20 | 2021-05-18 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | 53.7800 | -36,387 | -1,957 | 59,946 | ||||
| 2021-05-20 | 2021-05-18 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | 52.6300 | -14,216 | -748 | 96,333 | ||||
| 2021-05-20 | 2021-05-18 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | 51.6600 | -64,179 | -3,315 | 110,549 | ||||
| 2021-05-19 | 2021-05-18 | 4 | DeLong Mark Jeffrey | APLS | Stock Option (Right to Buy) | D | 15.52 | -2,000 | 48,000 | |||||
| 2021-05-19 | 2021-05-18 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 55.0000 | -2,000 | -110 | 9,490 | ||||
| 2021-05-19 | 2021-05-18 | 4 | DeLong Mark Jeffrey | APLS | Common Stock | D | 15.5200 | 2,000 | 31 | 11,490 | ||||
| 2021-05-18 | 2021-05-14 | 4 | Grossi Federico | APLS | Common Stock | D | 45.3900 | -500 | -23 | 55,430 | ||||
| 2021-05-18 | 2021-05-14 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -2,500 | 145,029 | |||||
| 2021-05-18 | 2021-05-14 | 4 | Machiels Alec | APLS | Common Stock | D | 45.3900 | -2,500 | -113 | 669,544 | ||||
| 2021-05-18 | 2021-05-14 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 2,500 | 7 | 672,044 | ||||
| 2021-05-04 | 2021-05-03 | 4 | Perry Nicole D | APLS | Stock Option (Right to Buy) | D | 3.76 | -1,000 | 9,161 | |||||
| 2021-05-04 | 2021-05-03 | 4 | Perry Nicole D | APLS | Common Stock | D | 50.7300 | -1,000 | -51 | 4,847 | ||||
| 2021-05-04 | 2021-05-03 | 4 | Perry Nicole D | APLS | Common Stock | D | 3.7600 | 1,000 | 4 | 5,847 | ||||
| 2021-05-04 | 2021-05-03 | 4 | Grossi Federico | APLS | Common Stock | D | 50.7300 | -600 | -30 | 55,614 | ||||
| 2021-05-03 | 2021-04-30 | 4 | Perry Nicole D | APLS | Stock Option (Right to Buy) | D | 3.76 | -1,000 | 10,161 | |||||
| 2021-05-03 | 2021-04-30 | 4 | Perry Nicole D | APLS | Common Stock | D | 50.0000 | -1,000 | -50 | 4,847 | ||||
| 2021-05-03 | 2021-04-30 | 4 | Perry Nicole D | APLS | Common Stock | D | 3.7600 | 1,000 | 4 | 5,847 | ||||
| 2021-04-29 | 2021-04-28 | 4 | Deschatelets Pascal | APLS | Stock Option (Right to Buy) | D | 2.67 | -4,500 | 381,499 | |||||
| 2021-04-29 | 2021-04-28 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 4,500 | 12 | 869,587 | ||||
| 2021-04-26 | 2021-04-23 | 4 | Deschatelets Pascal | APLS | Stock Option (Right to Buy) | D | 2.67 | -6,250 | 385,999 | |||||
| 2021-04-26 | 2021-04-23 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 46.1300 | -6,250 | -288 | 865,087 | ||||
| 2021-04-26 | 2021-04-23 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 6,250 | 17 | 871,337 | ||||
| 2021-04-26 | 2021-04-23 | 4 | Dunlop A. Sinclair | APLS | Stock Option (Right to Buy) | D | 14.00 | -10,000 | 61,894 | |||||
| 2021-04-26 | 2021-04-23 | 4 | Dunlop A. Sinclair | APLS | Common Stock | D | 14.0000 | 10,000 | 140 | 60,000 | ||||
| 2021-04-23 | 2021-04-22 | 4 | Watson David O. | APLS | Stock Option (Right to Buy) | D | 4.31 | -489 | 1,932 | |||||
| 2021-04-23 | 2021-04-22 | 4 | Watson David O. | APLS | Common Stock | D | 4.3100 | 489 | 2 | 97,261 | ||||
| 2021-04-22 | 2021-04-21 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -2,500 | 147,529 | |||||
| 2021-04-22 | 2021-04-21 | 4 | Machiels Alec | APLS | Common Stock | D | 45.7600 | -2,500 | -114 | 669,544 | ||||
| 2021-04-22 | 2021-04-21 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 2,500 | 7 | 672,044 | ||||
| 2021-04-19 | 2021-04-16 | 4 | Dunlop A. Sinclair | APLS | Stock Option (Right to Buy) | D | 14.00 | -50,000 | 71,894 | |||||
| 2021-04-19 | 2021-04-16 | 4 | Dunlop A. Sinclair | APLS | Common Stock | D | 14.0000 | 50,000 | 700 | 50,000 | ||||
| 2021-04-15 | 2021-04-14 | 4 | Grossi Federico | APLS | Common Stock | D | 42.8200 | -500 | -21 | 56,214 | ||||
| 2021-04-09 | 3 | DeLong Mark Jeffrey | APLS | Common Stock | D | 8,698 | ||||||||
| 2021-04-05 | 2021-04-01 | 4 | Grossi Federico | APLS | Common Stock | D | 43.4100 | -600 | -26 | 56,714 | ||||
| 2021-03-29 | 2021-03-25 | 4 | Brown Victoria L. | APLS | Common Stock | D | 41.1600 | -82 | -3 | 9,952 | ||||
| 2021-03-23 | 2021-03-22 | 4 | Watson David O. | APLS | Stock Option (Right to Buy) | D | 4.31 | -978 | 2,421 | |||||
| 2021-03-23 | 2021-03-22 | 4 | Watson David O. | APLS | Common Stock | D | 4.3100 | 978 | 4 | 96,772 | ||||
| 2021-03-19 | 2021-03-01 | 4 | Brown Victoria L. | APLS | Stock Option (Right to Buy) | D | 47.68 | 7,500 | 7,500 | |||||
| 2021-03-19 | 2021-03-01 | 4 | Brown Victoria L. | APLS | Common Stock | D | 1,250 | 10,034 | ||||||
| 2021-03-17 | 2021-03-15 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -2,500 | 150,029 | |||||
| 2021-03-17 | 2021-03-15 | 4 | Machiels Alec | APLS | Common Stock | D | 46.7700 | -2,500 | -117 | 669,544 | ||||
| 2021-03-17 | 2021-03-15 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 2,500 | 7 | 672,044 | ||||
| 2021-03-17 | 2021-03-15 | 4 | Grossi Federico | APLS | Common Stock | D | 46.7700 | -500 | -23 | 57,314 | ||||
| 2021-03-11 | 2021-03-10 | 4 | Deschatelets Pascal | APLS | Stock Option (Right to Buy) | D | 2.67 | -6,250 | 392,249 | |||||
| 2021-03-11 | 2021-03-10 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 50.7400 | -6,250 | -317 | 865,087 | ||||
| 2021-03-11 | 2021-03-10 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.6700 | 6,250 | 17 | 871,337 | ||||
| 2021-03-08 | 2021-03-05 | 4 | Grossi Federico | APLS | Stock Option (Right to Buy) | D | 3.20 | -5,000 | 34,073 | |||||
| 2021-03-08 | 2021-03-05 | 4 | Grossi Federico | APLS | Common Stock | D | 48.6150 | -5,000 | -243 | 57,814 | ||||
| 2021-03-08 | 2021-03-05 | 4 | Grossi Federico | APLS | Common Stock | D | 3.2000 | 5,000 | 16 | 62,814 | ||||
| 2021-03-03 | 2021-03-01 | 4 | Eisele Jeffrey | APLS | Stock Option (Right to Buy) | D | 47.68 | 7,500 | 7,500 | |||||
| 2021-03-03 | 2021-03-01 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 1,250 | 7,461 | ||||||
| 2021-03-03 | 2021-03-01 | 4 | Perry Nicole D | APLS | Stock Option (Right to Buy) | D | 3.76 | -2,000 | 11,161 | |||||
| 2021-03-03 | 2021-03-01 | 4 | Perry Nicole D | APLS | Common Stock | D | 50.0000 | -2,000 | -100 | 2,347 | ||||
| 2021-03-03 | 2021-03-01 | 4 | Perry Nicole D | APLS | Common Stock | D | 3.7600 | 2,000 | 8 | 4,347 | ||||
| 2021-03-03 | 2021-03-01 | 4 | Grossi Federico | APLS | Common Stock | D | 48.5800 | -600 | -29 | 57,814 | ||||
| 2021-02-17 | 2021-02-16 | 4 | Grossi Federico | APLS | Common Stock | D | 46.0000 | -500 | -23 | 58,414 | ||||
| 2021-02-17 | 2021-02-16 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -2,500 | 152,529 | |||||
| 2021-02-17 | 2021-02-16 | 4 | Machiels Alec | APLS | Common Stock | D | 46.0000 | -2,500 | -115 | 669,544 | ||||
| 2021-02-17 | 2021-02-16 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 2,500 | 7 | 672,044 | ||||
| 2021-02-11 | 2021-02-10 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 47.7200 | -680 | -32 | 29,290 | ||||
| 2021-02-11 | 2021-02-10 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 47.7200 | -858 | -41 | 34,261 | ||||
| 2021-02-11 | 2021-02-10 | 4 | Perry Nicole D | APLS | Common Stock | D | 47.7200 | -153 | -7 | 2,347 | ||||
| 2021-02-11 | 2021-02-10 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 47.7200 | -688 | -33 | 865,087 | ||||
| 2021-02-11 | 2021-02-10 | 4 | Townsend Adam J. | APLS | Common Stock | D | 47.7200 | -688 | -33 | 18,865 | ||||
| 2021-02-11 | 2021-02-10 | 4 | Brown Victoria L. | APLS | Common Stock | D | 47.7200 | -144 | -7 | 8,784 | ||||
| 2021-02-11 | 2021-02-10 | 4 | Grossi Federico | APLS | Common Stock | D | 47.7200 | -688 | -33 | 58,914 | ||||
| 2021-02-11 | 2021-02-10 | 4 | Francois Cedric | APLS | Common Stock | D | 47.7200 | -2,523 | -120 | 1,219,833 | ||||
| 2021-02-11 | 2021-02-10 | 4 | Watson David O. | APLS | Common Stock | D | 47.7200 | -468 | -22 | 95,794 | ||||
| 2021-02-10 | 2021-02-09 | 4 | Perry Nicole D | APLS | Stock Option (Right to Buy) | D | 3.76 | -2,000 | 13,161 | |||||
| 2021-02-10 | 2021-02-09 | 4 | Perry Nicole D | APLS | Common Stock | D | 50.0000 | -2,000 | -100 | 2,500 | ||||
| 2021-02-10 | 2021-02-09 | 4 | Perry Nicole D | APLS | Common Stock | D | 3.7600 | 2,000 | 8 | 4,500 | ||||
| 2021-02-04 | 2020-12-02 | 5 | Machiels Alec | APLS | Common Stock | I | 250,000 | 250,000 | ||||||
| 2021-02-04 | 2020-12-02 | 5 | Machiels Alec | APLS | Common Stock | D | -250,000 | 419,544 | ||||||
| 2021-02-04 | 2020-12-29 | 5 | Francois Cedric | APLS | Common Stock | I | 300,000 | 300,000 | ||||||
| 2021-02-04 | 2020-12-29 | 5 | Francois Cedric | APLS | Common Stock | D | -300,000 | 813,079 | ||||||
| 2021-02-02 | 2021-02-01 | 4 | Grossi Federico | APLS | Common Stock | D | 44.0000 | -600 | -26 | 59,602 | ||||
| 2021-02-01 | 2021-01-28 | 4 | Townsend Adam J. | APLS | Stock Option (Right to Buy) | D | 44.90 | 11,250 | 11,250 | |||||
| 2021-02-01 | 2021-01-28 | 4 | Townsend Adam J. | APLS | Stock Option (Right to Buy) | D | 44.90 | 45,000 | 45,000 | |||||
| 2021-02-01 | 2021-01-28 | 4 | Townsend Adam J. | APLS | Common Stock | D | 1,875 | 19,553 | ||||||
| 2021-02-01 | 2021-01-28 | 4 | Townsend Adam J. | APLS | Common Stock | D | 7,500 | 17,678 | ||||||
| 2021-02-01 | 2021-01-28 | 4 | Grossi Federico | APLS | Stock Option (Right to Buy) | D | 44.90 | 11,250 | 11,250 | |||||
| 2021-02-01 | 2021-01-28 | 4 | Grossi Federico | APLS | Stock Option (Right to Buy) | D | 44.90 | 45,000 | 45,000 | |||||
| 2021-02-01 | 2021-01-28 | 4 | Grossi Federico | APLS | Common Stock | D | 1,875 | 60,202 | ||||||
| 2021-02-01 | 2021-01-28 | 4 | Grossi Federico | APLS | Common Stock | D | 7,500 | 58,327 | ||||||
| 2021-02-01 | 2021-01-28 | 4 | Sullivan Timothy Eugene | APLS | Stock Option (Right to Buy) | D | 44.90 | 22,500 | 22,500 | |||||
| 2021-02-01 | 2021-01-28 | 4 | Sullivan Timothy Eugene | APLS | Stock Option (Right to Buy) | D | 44.90 | 45,000 | 45,000 | |||||
| 2021-02-01 | 2021-01-28 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 3,750 | 35,119 | ||||||
| 2021-02-01 | 2021-01-28 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 7,500 | 31,369 | ||||||
| 2021-02-01 | 2021-01-28 | 4 | Francois Cedric | APLS | Stock Option (Right to Buy) | D | 44.90 | 75,000 | 75,000 | |||||
| 2021-02-01 | 2021-01-28 | 4 | Francois Cedric | APLS | Stock Option (Right to Buy) | D | 44.90 | 150,000 | 150,000 | |||||
| 2021-02-01 | 2021-01-28 | 4 | Francois Cedric | APLS | Common Stock | D | 12,500 | 1,222,356 | ||||||
| 2021-02-01 | 2021-01-28 | 4 | Francois Cedric | APLS | Common Stock | D | 25,000 | 1,209,856 | ||||||
| 2021-02-01 | 2021-01-28 | 4 | Watson David O. | APLS | Stock Option (Right to Buy) | D | 44.90 | 11,250 | 11,250 | |||||
| 2021-02-01 | 2021-01-28 | 4 | Watson David O. | APLS | Stock Option (Right to Buy) | D | 44.90 | 45,000 | 45,000 | |||||
| 2021-02-01 | 2021-01-28 | 4 | Watson David O. | APLS | Common Stock | D | 1,875 | 96,262 | ||||||
| 2021-02-01 | 2021-01-28 | 4 | Watson David O. | APLS | Common Stock | D | 7,500 | 94,387 | ||||||
| 2021-02-01 | 2021-01-28 | 4 | SCHEIBLER LUKAS | APLS | Stock Option (Right to Buy) | D | 44.90 | 11,250 | 11,250 | |||||
| 2021-02-01 | 2021-01-28 | 4 | SCHEIBLER LUKAS | APLS | Stock Option (Right to Buy) | D | 44.90 | 45,000 | 45,000 | |||||
| 2021-02-01 | 2021-01-28 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 1,875 | 29,970 | ||||||
| 2021-02-01 | 2021-01-28 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 7,500 | 28,095 | ||||||
| 2021-02-01 | 2021-01-28 | 4 | Nicholson Nur | APLS | Stock Option (Right to Buy) | D | 44.90 | 11,250 | 11,250 | |||||
| 2021-02-01 | 2021-01-28 | 4 | Nicholson Nur | APLS | Stock Option (Right to Buy) | D | 44.90 | 45,000 | 45,000 | |||||
| 2021-02-01 | 2021-01-28 | 4 | Nicholson Nur | APLS | Common Stock | D | 1,875 | 9,375 | ||||||
| 2021-02-01 | 2021-01-28 | 4 | Nicholson Nur | APLS | Common Stock | D | 7,500 | 7,500 | ||||||
| 2021-02-01 | 2021-01-28 | 4 | Lewis Karen | APLS | Stock Option (Right to Buy) | D | 44.90 | 7,500 | 7,500 | |||||
| 2021-02-01 | 2021-01-28 | 4 | Lewis Karen | APLS | Stock Option (Right to Buy) | D | 44.90 | 30,000 | 30,000 | |||||
| 2021-02-01 | 2021-01-28 | 4 | Lewis Karen | APLS | Common Stock | D | 1,250 | 6,250 | ||||||
| 2021-02-01 | 2021-01-28 | 4 | Lewis Karen | APLS | Common Stock | D | 5,000 | 5,000 | ||||||
| 2021-02-01 | 2021-01-28 | 4 | Brown Victoria L. | APLS | Stock Option (Right to Buy) | D | 44.90 | 30,000 | 30,000 | |||||
| 2021-02-01 | 2021-01-28 | 4 | Brown Victoria L. | APLS | Common Stock | D | 5,000 | 8,928 | ||||||
| 2021-02-01 | 2021-01-28 | 4 | Eisele Jeffrey | APLS | Stock Option (Right to Buy) | D | 44.90 | 30,000 | 30,000 | |||||
| 2021-02-01 | 2021-01-28 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 5,000 | 6,211 | ||||||
| 2021-02-01 | 2021-01-28 | 4 | Perry Nicole D | APLS | Stock Option (Right to Buy) | D | 44.90 | 15,000 | 15,000 | |||||
| 2021-02-01 | 2021-01-28 | 4 | Perry Nicole D | APLS | Common Stock | D | 2,500 | 2,500 | ||||||
| 2021-02-01 | 2021-01-28 | 4 | Deschatelets Pascal | APLS | Stock Option (Right to Buy) | D | 44.90 | 11,250 | 11,250 | |||||
| 2021-02-01 | 2021-01-28 | 4 | Deschatelets Pascal | APLS | Stock Option (Right to Buy) | D | 44.90 | 45,000 | 45,000 | |||||
| 2021-02-01 | 2021-01-28 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 1,875 | 865,775 | ||||||
| 2021-02-01 | 2021-01-28 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 7,500 | 863,900 | ||||||
| 2021-01-29 | 2021-01-27 | 4 | Francois Cedric | APLS | Stock Option (Right to Buy) | D | 4.31 | -31,992 | 389,948 | |||||
| 2021-01-29 | 2021-01-27 | 4 | Francois Cedric | APLS | Stock Option (Right to Buy) | D | 3.76 | -39,785 | 273,840 | |||||
| 2021-01-29 | 2021-01-27 | 4 | Francois Cedric | APLS | Common Stock | D | 4.3100 | 31,992 | 138 | 1,184,856 | ||||
| 2021-01-29 | 2021-01-27 | 4 | Francois Cedric | APLS | Common Stock | D | 3.7600 | 39,785 | 150 | 1,152,864 | ||||
| 2021-01-29 | 2021-01-27 | 4 | Watson David O. | APLS | Stock Option (Right to Buy) | D | 4.31 | -20,042 | 3,399 | |||||
| 2021-01-29 | 2021-01-27 | 4 | Watson David O. | APLS | Stock Option (Right to Buy) | D | 3.76 | -23,441 | 0 | |||||
| 2021-01-29 | 2021-01-27 | 4 | Watson David O. | APLS | Common Stock | D | 4.3100 | 20,042 | 86 | 86,887 | ||||
| 2021-01-29 | 2021-01-27 | 4 | Watson David O. | APLS | Common Stock | D | 3.7600 | 23,441 | 88 | 66,845 | ||||
| 2021-01-26 | 2021-01-25 | 4 | Grossi Federico | APLS | Stock Option (Right to Buy) | D | 3.76 | -11,500 | 23,661 | |||||
| 2021-01-26 | 2021-01-25 | 4 | Grossi Federico | APLS | Stock Option (Right to Buy) | D | 3.20 | -3,500 | 39,073 | |||||
| 2021-01-26 | 2021-01-25 | 4 | Grossi Federico | APLS | Common Stock | D | 3.7600 | 11,500 | 43 | 50,827 | ||||
| 2021-01-26 | 2021-01-25 | 4 | Grossi Federico | APLS | Common Stock | D | 3.2000 | 3,500 | 11 | 39,327 | ||||
| 2021-01-19 | 2021-01-15 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -2,500 | 155,029 | |||||
| 2021-01-19 | 2021-01-15 | 4 | Machiels Alec | APLS | Common Stock | D | 53.1500 | -2,500 | -133 | 669,544 | ||||
| 2021-01-19 | 2021-01-15 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 2,500 | 7 | 672,044 | ||||
| 2021-01-15 | 2021-01-14 | 4 | Grossi Federico | APLS | Common Stock | D | 51.9900 | -4,000 | -208 | 35,827 | ||||
| 2021-01-05 | 2021-01-04 | 4 | Grossi Federico | APLS | Common Stock | D | 57.2400 | -600 | -34 | 39,827 | ||||
| 2021-01-05 | 2021-01-04 | 4 | Perry Nicole D | APLS | Stock Option (Right to Buy) | D | 3.76 | -2,000 | 15,161 | |||||
| 2021-01-05 | 2021-01-04 | 4 | Perry Nicole D | APLS | Common Stock | D | 57.2400 | -2,000 | -114 | 0 | ||||
| 2021-01-05 | 2021-01-04 | 4 | Perry Nicole D | APLS | Common Stock | D | 3.7600 | 2,000 | 8 | 2,000 | ||||
| 2021-01-04 | 2021-01-01 | 4 | FONTEYNE PAUL R. | APLS | Stock Option (Right to Buy) | D | 57.20 | 27,600 | 27,600 | |||||
| 2021-01-04 | 2021-01-01 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 57.20 | 27,600 | 27,600 | |||||
| 2021-01-04 | 2021-01-01 | 4 | Chan Gerald | APLS | Stock Option (Right to Buy) | D | 57.20 | 27,600 | 27,600 | |||||
| 2021-01-04 | 2021-01-01 | 4 | O'Brien Stephanie Monaghan | APLS | Stock Option (Right to Buy) | D | 57.20 | 27,600 | 27,600 | |||||
| 2021-01-04 | 2021-01-01 | 4 | Dunlop A. Sinclair | APLS | Stock Option (Right to Buy) | D | 57.20 | 27,600 | 27,600 | |||||
| 2020-12-23 | 2020-12-23 | 4 | Eisele Jeffrey | APLS | Common Stock | D | 1,211 | 1,211 | ||||||
| 2020-12-16 | 2020-12-15 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -2,500 | 157,529 | |||||
| 2020-12-16 | 2020-12-15 | 4 | Machiels Alec | APLS | Common Stock | D | 52.1600 | -2,500 | -130 | 669,544 | ||||
| 2020-12-16 | 2020-12-15 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 2,500 | 7 | 672,044 | ||||
| 2020-12-16 | 2020-12-15 | 4 | Francois Cedric | APLS | Common Stock | D | 52.1600 | -5,000 | -261 | 1,113,079 | ||||
| 2020-12-15 | 2020-12-14 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | 56.2500 | -214 | -12 | 174,728 | ||||
| 2020-12-15 | 2020-12-14 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | 55.0100 | -17,132 | -942 | 174,942 | ||||
| 2020-12-15 | 2020-12-14 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | 53.8600 | -7,654 | -412 | 192,074 | ||||
| 2020-12-15 | 2020-12-14 | 4 | Watson David O. | APLS | Stock Option (Right to Buy) | D | 13.85 | -8,398 | 21,667 | |||||
| 2020-12-15 | 2020-12-14 | 4 | Watson David O. | APLS | Common Stock | D | 55.9080 | -200 | -11 | 43,404 | ||||
| 2020-12-15 | 2020-12-14 | 4 | Watson David O. | APLS | Common Stock | D | 55.0010 | -900 | -50 | 43,604 | ||||
| 2020-12-15 | 2020-12-14 | 4 | Watson David O. | APLS | Common Stock | D | 53.8610 | -900 | -48 | 44,504 | ||||
| 2020-12-15 | 2020-12-14 | 4 | Watson David O. | APLS | Common Stock | D | 52.7270 | -1,163 | -61 | 45,404 | ||||
| 2020-12-15 | 2020-12-14 | 4 | Watson David O. | APLS | Common Stock | D | 51.3160 | -2,526 | -130 | 46,567 | ||||
| 2020-12-15 | 2020-12-14 | 4 | Watson David O. | APLS | Common Stock | D | 50.6070 | -2,709 | -137 | 49,093 | ||||
| 2020-12-15 | 2020-12-14 | 4 | Watson David O. | APLS | Common Stock | D | 13.8500 | 8,398 | 116 | 51,802 | ||||
| 2020-12-15 | 2020-12-11 | 4 | Watson David O. | APLS | Stock Option (Right to Buy) | D | 13.85 | -9,935 | 30,065 | |||||
| 2020-12-15 | 2020-12-11 | 4 | Watson David O. | APLS | Common Stock | D | 50.0000 | -9,935 | -497 | 43,404 | ||||
| 2020-12-15 | 2020-12-11 | 4 | Watson David O. | APLS | Common Stock | D | 13.8500 | 9,935 | 138 | 53,339 | ||||
| 2020-12-09 | 2020-12-08 | 4 | SCHEIBLER LUKAS | APLS | Stock Option (Right to Buy) | D | 26.73 | -7,482 | 137,518 | |||||
| 2020-12-09 | 2020-12-08 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 26.7300 | 7,482 | 200 | 20,595 | ||||
| 2020-12-08 | 2020-12-04 | 4 | Perry Nicole D | APLS | Stock Option (Right to Buy) | D | 3.76 | -18,000 | 17,161 | |||||
| 2020-12-08 | 2020-12-04 | 4 | Perry Nicole D | APLS | Common Stock | D | 50.0000 | -18,000 | -900 | 0 | ||||
| 2020-12-08 | 2020-12-04 | 4 | Perry Nicole D | APLS | Common Stock | D | 3.7600 | 18,000 | 68 | 18,000 | ||||
| 2020-12-08 | 2020-12-04 | 4 | Grossi Federico | APLS | Stock Option (Right to Buy) | D | 3.20 | -7,250 | 42,573 | |||||
| 2020-12-08 | 2020-12-04 | 4 | Grossi Federico | APLS | Common Stock | D | 3.2000 | 7,250 | 23 | 40,427 | ||||
| 2020-12-07 | 2020-12-07 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | 51.0000 | -9,470 | -483 | 199,728 | ||||
| 2020-12-07 | 2020-12-07 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | 50.4100 | -9,094 | -458 | 209,198 | ||||
| 2020-12-07 | 2020-12-04 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | 51.0500 | -1,384 | -71 | 218,292 | ||||
| 2020-12-07 | 2020-12-04 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | 50.0400 | -5,052 | -253 | 219,676 | ||||
| 2020-12-02 | 2020-12-01 | 4 | Francois Cedric | APLS | Stock Option (Right to Buy) | D | 3.76 | -40,000 | 313,625 | |||||
| 2020-12-02 | 2020-12-01 | 4 | Francois Cedric | APLS | Common Stock | D | 3.7600 | 40,000 | 150 | 1,118,079 | ||||
| 2020-12-02 | 2020-12-01 | 4 | Grossi Federico | APLS | Common Stock | D | 48.2500 | -600 | -29 | 33,177 | ||||
| 2020-11-17 | 2020-11-16 | 4 | Francois Cedric | APLS | Common Stock | D | 39.3800 | -5,000 | -197 | 1,078,079 | ||||
| 2020-11-17 | 2020-11-16 | 4 | Grossi Federico | APLS | Stock Option (Right to Buy) | D | 3.20 | -5,750 | 49,823 | |||||
| 2020-11-17 | 2020-11-16 | 4 | Grossi Federico | APLS | Common Stock | D | 3.2000 | 5,750 | 18 | 33,777 | ||||
| 2020-11-17 | 2020-11-16 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -2,500 | 160,029 | |||||
| 2020-11-17 | 2020-11-16 | 4 | Machiels Alec | APLS | Common Stock | D | 39.3800 | -2,500 | -98 | 669,544 | ||||
| 2020-11-17 | 2020-11-16 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 2,500 | 7 | 672,044 | ||||
| 2020-11-03 | 2020-11-02 | 4 | Grossi Federico | APLS | Common Stock | D | 31.0900 | -600 | -19 | 27,725 | ||||
| 2020-10-16 | 2020-10-15 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -2,500 | 162,529 | |||||
| 2020-10-16 | 2020-10-15 | 4 | Machiels Alec | APLS | Common Stock | D | 35.0000 | -2,500 | -88 | 669,544 | ||||
| 2020-10-16 | 2020-10-15 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 2,500 | 7 | 672,044 | ||||
| 2020-10-16 | 2020-10-15 | 4 | Francois Cedric | APLS | Common Stock | D | 34.4600 | -5,000 | -172 | 1,083,079 | ||||
| 2020-10-09 | 2020-10-07 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -7,500 | 165,029 | |||||
| 2020-10-09 | 2020-10-07 | 4 | Machiels Alec | APLS | Common Stock | D | 35.0000 | -7,500 | -262 | 669,544 | ||||
| 2020-10-09 | 2020-10-07 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 7,500 | 20 | 677,044 | ||||
| 2020-10-09 | 2020-10-07 | 4 | Brown Victoria L. | APLS | Stock Option (Right to Buy) | D | 18.98 | -12,000 | 39,268 | |||||
| 2020-10-09 | 2020-10-07 | 4 | Brown Victoria L. | APLS | Common Stock | D | 35.0000 | -12,000 | -420 | 3,607 | ||||
| 2020-10-09 | 2020-10-07 | 4 | Brown Victoria L. | APLS | Common Stock | D | 18.9800 | 12,000 | 228 | 15,607 | ||||
| 2020-10-02 | 2020-10-01 | 4 | Grossi Federico | APLS | Common Stock | D | 30.2200 | -600 | -18 | 28,325 | ||||
| 2020-09-16 | 2020-09-15 | 4 | Francois Cedric | APLS | Common Stock | D | 30.9600 | -5,000 | -155 | 1,088,079 | ||||
| 2020-09-02 | 2020-09-01 | 4 | Grossi Federico | APLS | Common Stock | D | 31.5800 | -600 | -19 | 28,925 | ||||
| 2020-08-21 | 2020-08-20 | 4 | Francois Cedric | APLS | Common Stock | D | 30.0000 | -3,457 | -104 | 1,093,079 | ||||
| 2020-08-20 | 2020-08-18 | 4 | Francois Cedric | APLS | Common Stock | D | 30.0000 | -1,543 | -46 | 1,096,536 | ||||
| 2020-08-05 | 2020-08-03 | 4 | Grossi Federico | APLS | Common Stock | D | 26.2800 | -600 | -16 | 29,525 | ||||
| 2020-07-16 | 2020-07-15 | 4 | Francois Cedric | APLS | Common Stock | D | 32.1200 | -5,000 | -161 | 1,098,079 | ||||
| 2020-07-02 | 2020-07-01 | 4 | Grossi Federico | APLS | Common Stock | D | 32.4300 | -850 | -28 | 30,125 | ||||
| 2020-06-16 | 2020-06-15 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -2,500 | 172,529 | |||||
| 2020-06-16 | 2020-06-15 | 4 | Machiels Alec | APLS | Common Stock | D | 30.2100 | -2,500 | -76 | 669,544 | ||||
| 2020-06-16 | 2020-06-15 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 2,500 | 7 | 672,044 | ||||
| 2020-06-16 | 2020-06-15 | 4 | Grossi Federico | APLS | Common Stock | D | 30.2100 | -856 | -26 | 30,975 | ||||
| 2020-06-16 | 2020-06-15 | 4 | Francois Cedric | APLS | Common Stock | D | 30.2100 | -5,000 | -151 | 1,103,079 | ||||
| 2020-05-19 | 2020-05-15 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -2,500 | 175,029 | |||||
| 2020-05-19 | 2020-05-15 | 4 | Machiels Alec | APLS | Common Stock | D | 30.0000 | -2,500 | -75 | 669,544 | ||||
| 2020-05-19 | 2020-05-15 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 2,500 | 7 | 672,044 | ||||
| 2020-05-19 | 2020-05-15 | 4 | Francois Cedric | APLS | Common Stock | D | 29.9200 | -5,000 | -150 | 1,108,079 | ||||
| 2020-05-12 | 2020-05-08 | 4 | FONTEYNE PAUL R. | APLS | Common Stock | D | 31.8068 | 5,000 | 159 | 5,000 | ||||
| 2020-04-27 | 3 | Brown Victoria L. | APLS | Common Stock | D | 6,250 | ||||||||
| 2020-04-27 | 3 | Brown Victoria L. | APLS | Common Stock | D | 6,250 | ||||||||
| 2020-04-27 | 3 | Brown Victoria L. | APLS | Common Stock | D | 6,250 | ||||||||
| 2020-04-17 | 2020-04-15 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -2,500 | 177,529 | |||||
| 2020-04-17 | 2020-04-15 | 4 | Machiels Alec | APLS | Common Stock | D | 30.0000 | -2,500 | -75 | 669,544 | ||||
| 2020-04-17 | 2020-04-15 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 2,500 | 7 | 672,044 | ||||
| 2020-04-17 | 2020-04-15 | 4 | Francois Cedric | APLS | Common Stock | D | 29.7700 | -5,000 | -149 | 1,113,079 | ||||
| 2020-04-06 | 2020-04-02 | 4 | FONTEYNE PAUL R. | APLS | Stock Option (Right to Buy) | D | 26.13 | 37,500 | 37,500 | |||||
| 2020-03-26 | 2020-03-25 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -2,500 | 180,029 | |||||
| 2020-03-26 | 2020-03-25 | 4 | Machiels Alec | APLS | Common Stock | D | 30.0000 | -2,500 | -75 | 669,544 | ||||
| 2020-03-26 | 2020-03-25 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 2,500 | 7 | 672,044 | ||||
| 2020-03-18 | 2020-03-17 | 4 | Francois Cedric | APLS | Stock Option (Right to Buy) | D | 2.14 | -30,637 | 0 | |||||
| 2020-03-18 | 2020-03-17 | 4 | Francois Cedric | APLS | Common Stock | D | 2.1400 | 30,637 | 66 | 1,083,704 | ||||
| 2020-03-18 | 2020-03-16 | 4 | Francois Cedric | APLS | Stock Option (Right to Buy) | D | 2.14 | -30,637 | 30,637 | |||||
| 2020-03-18 | 2020-03-16 | 4 | Francois Cedric | APLS | Common Stock | D | 23.8600 | -300 | -7 | 1,053,067 | ||||
| 2020-03-18 | 2020-03-16 | 4 | Francois Cedric | APLS | Common Stock | D | 22.2780 | -3,212 | -72 | 1,053,367 | ||||
| 2020-03-18 | 2020-03-16 | 4 | Francois Cedric | APLS | Common Stock | D | 21.5790 | -15,065 | -325 | 1,056,579 | ||||
| 2020-03-18 | 2020-03-16 | 4 | Francois Cedric | APLS | Common Stock | D | 20.6930 | -12,060 | -250 | 1,071,644 | ||||
| 2020-03-18 | 2020-03-16 | 4 | Francois Cedric | APLS | Common Stock | D | 22.2860 | -700 | -16 | 1,083,704 | ||||
| 2020-03-18 | 2020-03-16 | 4 | Francois Cedric | APLS | Common Stock | D | 21.5690 | -2,192 | -47 | 1,084,404 | ||||
| 2020-03-18 | 2020-03-16 | 4 | Francois Cedric | APLS | Common Stock | D | 20.7280 | -2,108 | -44 | 1,086,596 | ||||
| 2020-03-18 | 2020-03-16 | 4 | Francois Cedric | APLS | Common Stock | D | 2.1400 | 30,637 | 66 | 1,088,704 | ||||
| 2020-03-12 | 2020-03-10 | 4 | Deschatelets Pascal | APLS | Common Stock | D | -161,656 | 847,025 | ||||||
| 2020-02-20 | 2020-02-19 | 4 | Francois Cedric | APLS | Stock Option (Right to Buy) | D | 2.14 | -30,637 | 61,274 | |||||
| 2020-02-20 | 2020-02-19 | 4 | Francois Cedric | APLS | Common Stock | D | 2.1400 | 30,637 | 66 | 1,058,067 | ||||
| 2020-02-20 | 2020-02-18 | 4 | Francois Cedric | APLS | Stock Option (Right to Buy) | D | 2.14 | -30,637 | 91,911 | |||||
| 2020-02-20 | 2020-02-18 | 4 | Francois Cedric | APLS | Common Stock | D | 40.6660 | -5,000 | -203 | 1,027,430 | ||||
| 2020-02-20 | 2020-02-18 | 4 | Francois Cedric | APLS | Common Stock | D | 40.6630 | -30,637 | -1,246 | 1,032,430 | ||||
| 2020-02-20 | 2020-02-18 | 4 | Francois Cedric | APLS | Common Stock | D | 2.1400 | 30,637 | 66 | 1,063,067 | ||||
| 2020-02-19 | 2020-02-14 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -2,500 | 182,529 | |||||
| 2020-02-19 | 2020-02-14 | 4 | Machiels Alec | APLS | Common Stock | D | 42.3500 | -2,500 | -106 | 669,544 | ||||
| 2020-02-19 | 2020-02-14 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 2,500 | 7 | 672,044 | ||||
| 2020-02-14 | 2020-02-13 | 4 | Deschatelets Pascal | APLS | Stock Option (Right to Buy) | D | 2.14 | -117,205 | 0 | |||||
| 2020-02-14 | 2020-02-13 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 40.9790 | -55,398 | -2,270 | 1,008,681 | ||||
| 2020-02-14 | 2020-02-13 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.1400 | 117,205 | 251 | 1,064,079 | ||||
| 2020-02-14 | 2020-02-12 | 4 | Deschatelets Pascal | APLS | Stock Option (Right to Buy) | D | 2.14 | -117,206 | 117,205 | |||||
| 2020-02-14 | 2020-02-12 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 42.8030 | -52,075 | -2,229 | 946,874 | ||||
| 2020-02-14 | 2020-02-12 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 2.1400 | 117,206 | 251 | 998,949 | ||||
| 2020-02-12 | 2020-02-10 | 4 | Watson David O. | APLS | Stock option (right to buy) | D | 2.67 | -7,505 | 0 | |||||
| 2020-02-12 | 2020-02-10 | 4 | Watson David O. | APLS | Stock option (right to buy) | D | 44.33 | 38,250 | 38,250 | |||||
| 2020-02-12 | 2020-02-10 | 4 | Watson David O. | APLS | Common Stock | D | 2.6700 | 7,505 | 20 | 42,922 | ||||
| 2020-02-12 | 2020-02-10 | 4 | Watson David O. | APLS | Common Stock | D | 44.5000 | -5,000 | -222 | 35,417 | ||||
| 2020-02-12 | 2020-02-10 | 4 | Watson David O. | APLS | Common Stock | D | 6,375 | 40,417 | ||||||
| 2020-02-12 | 2020-02-10 | 4 | Grossi Federico | APLS | Stock option (right to buy) | D | 44.33 | 56,250 | 56,250 | |||||
| 2020-02-12 | 2020-02-10 | 4 | Grossi Federico | APLS | Common Stock | D | 9,375 | 31,831 | ||||||
| 2020-02-12 | 2020-02-10 | 4 | Sadr Ahmad | APLS | Stock option (right to buy) | D | 44.33 | 16,350 | 16,350 | |||||
| 2020-02-12 | 2020-02-10 | 4 | Sadr Ahmad | APLS | Common Stock | D | 2,725 | 2,725 | ||||||
| 2020-02-12 | 2020-02-10 | 4 | Lackner Thomas A. | APLS | Stock option (right to buy) | D | 44.33 | 16,350 | 16,350 | |||||
| 2020-02-12 | 2020-02-10 | 4 | Lackner Thomas A. | APLS | Common Stock | D | 2,725 | 7,725 | ||||||
| 2020-02-12 | 2020-02-10 | 4 | Perry Nicole D | APLS | Stock option (right to buy) | D | 44.33 | 15,000 | 15,000 | |||||
| 2020-02-12 | 2020-02-10 | 4 | Perry Nicole D | APLS | Common Stock | D | 2,500 | 2,500 | ||||||
| 2020-02-12 | 2020-02-10 | 4 | Celona Lucia | APLS | Stock option (right to buy) | D | 44.33 | 31,275 | 31,275 | |||||
| 2020-02-12 | 2020-02-10 | 4 | Celona Lucia | APLS | Common Stock | D | 5,213 | 5,213 | ||||||
| 2020-02-12 | 2020-02-10 | 4 | Townsend Adam J. | APLS | Stock option (right to buy) | D | 44.33 | 56,250 | 56,250 | |||||
| 2020-02-12 | 2020-02-10 | 4 | Townsend Adam J. | APLS | Common Stock | D | 9,375 | 9,375 | ||||||
| 2020-02-12 | 2020-02-10 | 4 | Francois Cedric | APLS | Stock option (right to buy) | D | 44.33 | 206,250 | 206,250 | |||||
| 2020-02-12 | 2020-02-10 | 4 | Francois Cedric | APLS | Common Stock | D | 34,375 | 1,066,805 | ||||||
| 2020-02-12 | 2020-02-10 | 4 | Sullivan Timothy Eugene | APLS | Stock option (right to buy) | D | 44.33 | 70,125 | 70,125 | |||||
| 2020-02-12 | 2020-02-10 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 11,688 | 23,387 | ||||||
| 2020-02-12 | 2020-02-10 | 4 | Deschatelets Pascal | APLS | Stock option (right to buy) | D | 44.33 | 56,250 | 56,250 | |||||
| 2020-02-12 | 2020-02-10 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 9,375 | 891,118 | ||||||
| 2020-02-12 | 2020-02-10 | 4 | SCHEIBLER LUKAS | APLS | Stock option (right to buy) | D | 44.33 | 56,250 | 56,250 | |||||
| 2020-02-12 | 2020-02-10 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 9,375 | 12,310 | ||||||
| 2020-02-05 | 3/A | Machiels Alec | APLS | Common Stock | I | 1,020 | ||||||||
| 2020-01-28 | 2020-01-27 | 4 | Watson David O. | APLS | Stock Option (Right to Buy) | D | 2.67 | -15,000 | 7,505 | |||||
| 2020-01-28 | 2020-01-27 | 4 | Watson David O. | APLS | Common Stock | D | 2.6700 | 15,000 | 40 | 34,042 | ||||
| 2020-01-28 | 2020-01-27 | 4 | Watson David O. | APLS | Common Stock | D | 40.4670 | -3,000 | -121 | 19,042 | ||||
| 2020-01-21 | 2020-01-13 | 4 | Morningside Venture Investments Ltd | APLS | Common Stock | D | 37.0000 | 540,540 | 20,000 | 12,556,342 | ||||
| 2020-01-21 | 2020-01-16 | 4 | Francois Cedric | APLS | Stock Option (Right to Buy) | D | 2.14 | -30,637 | 122,548 | |||||
| 2020-01-21 | 2020-01-16 | 4 | Francois Cedric | APLS | Common Stock | D | 2.1400 | 30,637 | 66 | 1,032,430 | ||||
| 2020-01-17 | 2020-01-15 | 4 | Francois Cedric | APLS | Stock Option (Right to Buy) | D | 2.14 | -30,638 | 153,185 | |||||
| 2020-01-17 | 2020-01-15 | 4 | Francois Cedric | APLS | Common Stock | D | 2.1400 | 30,638 | 66 | 1,001,793 | ||||
| 2020-01-17 | 2020-01-15 | 4 | Francois Cedric | APLS | Common Stock | D | 41.4700 | -5,000 | -207 | 1,001,793 | ||||
| 2020-01-17 | 2020-01-15 | 4 | Francois Cedric | APLS | Common Stock | D | 42.5470 | -4,562 | -194 | 1,006,793 | ||||
| 2020-01-17 | 2020-01-15 | 4 | Francois Cedric | APLS | Common Stock | D | 42.1590 | -26,076 | -1,099 | 1,011,355 | ||||
| 2020-01-17 | 2020-01-15 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 2.67 | -2,500 | 185,029 | |||||
| 2020-01-17 | 2020-01-15 | 4 | Machiels Alec | APLS | Common Stock | D | 41.4700 | -2,500 | -104 | 669,544 | ||||
| 2020-01-17 | 2020-01-15 | 4 | Machiels Alec | APLS | Common Stock | D | 2.6700 | 2,500 | 7 | 672,044 | ||||
| 2020-01-03 | 2020-01-01 | 4 | O'Brien Stephanie Monaghan | APLS | Stock Option (Right to Buy) | D | 30.62 | 30.6200 | 27,600 | 845 | 27,600 | |||
| 2020-01-03 | 2020-01-01 | 4 | Machiels Alec | APLS | Stock Option (Right to Buy) | D | 30.62 | 30.6200 | 27,600 | 845 | 27,600 | |||
| 2020-01-03 | 2020-01-01 | 4 | Dunlop A. Sinclair | APLS | Stock Option (Right to Buy) | D | 30.62 | 30.6200 | 27,600 | 845 | 27,600 | |||
| 2020-01-03 | 2020-01-01 | 4 | Chan Gerald | APLS | Stock Option (Right to Buy) | D | 30.62 | 30.6200 | 27,600 | 845 | 27,600 | |||
| 2019-12-20 | 2019-12-20 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | 29.5300 | -25,000 | -738 | 224,728 | ||||
| 2019-12-20 | 2019-12-19 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | 29.5100 | -31,000 | -915 | 249,728 | ||||
| 2019-12-20 | 2019-12-19 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | 28.9900 | -54,110 | -1,569 | 320,681 | ||||
| 2019-12-20 | 2019-12-18 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | 28.5500 | -25,890 | -739 | 374,791 | ||||
| 2019-12-17 | 2019-12-16 | 4 | Francois Cedric | APLS | Common Stock | D | 27.9500 | -5,000 | -140 | 1,006,793 | ||||
| 2019-11-18 | 2019-11-15 | 4 | Francois Cedric | APLS | Common Stock | D | 27.2810 | -5,000 | -136 | 1,011,793 | ||||
| 2019-10-16 | 2019-10-15 | 4 | Francois Cedric | APLS | Common Stock | D | 26.6130 | -3,524 | -94 | 1,016,793 | ||||
| 2019-10-16 | 2019-10-15 | 4 | Francois Cedric | APLS | Common Stock | D | 25.5870 | -1,476 | -38 | 1,020,317 | ||||
| 2019-09-26 | 2019-09-25 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 25.6410 | -1,010 | -26 | 881,743 | ||||
| 2019-09-26 | 2019-09-25 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 25.2380 | -20,531 | -518 | 882,753 | ||||
| 2019-09-25 | 2019-09-24 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 24.9580 | -1,295 | -32 | 903,284 | ||||
| 2019-09-25 | 2019-09-24 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 24.5610 | -20,307 | -499 | 904,579 | ||||
| 2019-09-25 | 2019-09-23 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 25.5300 | -100 | -3 | 924,886 | ||||
| 2019-09-25 | 2019-09-23 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 25.0680 | -20,758 | -520 | 924,986 | ||||
| 2019-09-17 | 2019-09-16 | 4 | Francois Cedric | APLS | Common Stock | D | 27.1700 | -260 | -7 | 1,021,793 | ||||
| 2019-09-17 | 2019-09-16 | 4 | Francois Cedric | APLS | Common Stock | D | 26.5580 | -4,740 | -126 | 1,022,053 | ||||
| 2019-09-03 | 2019-08-29 | 4 | Sullivan Timothy Eugene | APLS | Common Stock | D | 29.7145 | 11,699 | 348 | 11,699 | ||||
| 2019-08-26 | 2019-08-23 | 4 | Francois Cedric | APLS | Stock Option (Right to Buy) | D | 2.67 | -37,505 | 478,200 | |||||
| 2019-08-26 | 2019-08-23 | 4 | Francois Cedric | APLS | Common Stock | D | 2.6700 | 37,505 | 100 | 1,026,793 | ||||
| 2019-08-16 | 2019-08-15 | 4 | Francois Cedric | APLS | Stock Option (Right to Buy) | D | 2.14 | -10,000 | 183,823 | |||||
| 2019-08-16 | 2019-08-15 | 4 | Francois Cedric | APLS | Common Stock | D | 27.0000 | -2,246 | -61 | 989,288 | ||||
| 2019-08-16 | 2019-08-15 | 4 | Francois Cedric | APLS | Common Stock | D | 26.7430 | -7,754 | -207 | 991,534 | ||||
| 2019-08-16 | 2019-08-15 | 4 | Francois Cedric | APLS | Common Stock | D | 2.1400 | 10,000 | 21 | 999,288 | ||||
| 2019-08-09 | 2019-08-07 | 4 | Watson David O. | APLS | Stock Option (Right to Buy) | D | 2.67 | -5,000 | 22,505 | |||||
| 2019-08-09 | 2019-08-07 | 4 | Watson David O. | APLS | Common Stock | D | 2.6700 | 5,000 | 13 | 22,042 | ||||
| 2019-07-01 | 2019-06-27 | 4 | Francois Cedric | APLS | Stock Option (Right to Buy) | D | 2.14 | -275,000 | 193,823 | |||||
| 2019-07-01 | 2019-06-27 | 4 | Francois Cedric | APLS | Common Stock | D | 2.1400 | 275,000 | 588 | 989,288 | ||||
| 2019-04-15 | 3 | Lackner Thomas A. | APLS | Common Stock | D | 10,000 | ||||||||
| 2019-04-15 | 3 | Lackner Thomas A. | APLS | Common Stock | D | 10,000 | ||||||||
| 2019-04-15 | 3 | Lackner Thomas A. | APLS | Common Stock | D | 10,000 | ||||||||
| 2019-03-13 | 2019-03-11 | 4 | Morningside Venture Investments Ltd | APLS | Common Stock | D | 17.0000 | 441,176 | 7,500 | 12,015,802 | ||||
| 2019-02-12 | 2019-02-08 | 4 | Watson David O. | APLS | Stock option (right to buy) | D | 13.85 | 40,000 | 40,000 | |||||
| 2019-02-12 | 2019-02-08 | 4 | Perry Nicole D | APLS | Stock option (right to buy) | D | 13.85 | 22,000 | 22,000 | |||||
| 2019-02-12 | 2019-02-08 | 4 | SCHEIBLER LUKAS | APLS | Stock option (right to buy) | D | 13.85 | 85,000 | 85,000 | |||||
| 2019-02-12 | 2019-02-08 | 4 | Francois Cedric | APLS | Stock option (right to buy) | D | 13.85 | 281,000 | 281,000 | |||||
| 2019-02-12 | 2019-02-08 | 4 | Grossi Federico | APLS | Stock option (right to buy) | D | 13.85 | 85,000 | 85,000 | |||||
| 2019-02-12 | 2019-02-08 | 4 | Deschatelets Pascal | APLS | Stock option (right to buy) | D | 13.85 | 95,000 | 95,000 | |||||
| 2019-02-12 | 2019-02-08 | 4 | Sullivan Timothy Eugene | APLS | Stock option (right to buy) | D | 13.85 | 95,000 | 95,000 | |||||
| 2019-01-03 | 2019-01-01 | 4 | Dunlop A. Sinclair | APLS | Stock option (right to buy) | D | 13.19 | 17,580 | 17,580 | |||||
| 2019-01-03 | 2019-01-01 | 4 | O'Brien Stephanie Monaghan | APLS | Stock option (right to buy) | D | 13.19 | 17,580 | 17,580 | |||||
| 2019-01-03 | 2019-01-01 | 4 | Chan Gerald | APLS | Stock option (right to buy) | D | 13.19 | 17,580 | 17,580 | |||||
| 2019-01-03 | 2019-01-01 | 4 | Machiels Alec | APLS | Stock option (right to buy) | D | 13.19 | 17,580 | 17,580 | |||||
| 2018-11-15 | 2018-11-14 | 4 | Axon Steven | APLS | Stock Option (Right to Buy) | D | 2.59 | -11,500 | 348,389 | |||||
| 2018-11-15 | 2018-11-14 | 4 | Axon Steven | APLS | Common Stock | D | 2.5900 | 11,500 | 30 | 50,110 | ||||
| 2018-11-15 | 2018-11-14 | 4 | Grossi Federico | APLS | Stock Option (Right to Buy) | D | 3.20 | -6,250 | 55,573 | |||||
| 2018-11-15 | 2018-11-14 | 4 | Grossi Federico | APLS | Common Stock | D | 3.2000 | 6,250 | 20 | 22,456 | ||||
| 2018-09-24 | 2018-09-21 | 4 | Morningside Venture Investments Ltd | APLS | Common Stock | D | 19.8400 | 40,000 | 794 | 11,574,626 | ||||
| 2018-09-24 | 2018-09-20 | 4 | Morningside Venture Investments Ltd | APLS | Common Stock | D | 19.4300 | 21,724 | 422 | 11,534,626 | ||||
| 2018-09-24 | 2018-09-20 | 4 | Morningside Venture Investments Ltd | APLS | Common Stock | D | 18.7900 | 19,599 | 368 | 11,512,902 | ||||
| 2018-09-19 | 2018-09-19 | 4 | Morningside Venture Investments Ltd | APLS | Common Stock | D | 18.0900 | 60,000 | 1,085 | 11,493,303 | ||||
| 2018-09-19 | 2018-09-18 | 4 | Morningside Venture Investments Ltd | APLS | Common Stock | D | 18.4700 | 40,000 | 739 | 11,433,303 | ||||
| 2018-09-19 | 2018-09-17 | 4 | Morningside Venture Investments Ltd | APLS | Common Stock | D | 18.8400 | 8,600 | 162 | 11,393,303 | ||||
| 2018-09-19 | 2018-09-17 | 4 | Morningside Venture Investments Ltd | APLS | Common Stock | D | 18.5000 | 31,400 | 581 | 11,384,703 | ||||
| 2018-09-17 | 2018-09-14 | 4 | Watson David O. | APLS | Stock Option (right to buy) | D | 2.67 | -32,818 | 27,505 | |||||
| 2018-09-17 | 2018-09-14 | 4 | Watson David O. | APLS | Common Stock | D | 18.7840 | -15,776 | -296 | 17,042 | ||||
| 2018-09-17 | 2018-09-14 | 4 | Watson David O. | APLS | Common Stock | D | 2.6700 | 32,818 | 88 | 32,818 | ||||
| 2018-05-30 | 2018-05-29 | 4 | Watson David O. | APLS | Stock Option (right to buy) | D | 2.67 | -624 | 60,323 | |||||
| 2018-05-30 | 2018-05-29 | 4 | Watson David O. | APLS | Common Stock | D | -624 | 0 | ||||||
| 2018-05-30 | 2018-05-29 | 4 | Watson David O. | APLS | Common Stock | D | 2.6700 | 624 | 2 | 624 | ||||
| 2018-05-29 | 2018-05-24 | 4 | SCHEIBLER LUKAS | APLS | Common Stock | D | 20.3700 | 2,935 | 60 | 2,935 | ||||
| 2018-05-09 | 2018-05-07 | 4 | Deschatelets Pascal | APLS | Common Stock | D | 384,292 | 945,744 | ||||||
| 2018-05-09 | 2018-05-07 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | 94,357 | 280,728 | ||||||
| 2018-05-09 | 2018-05-07 | 4 | Francois Cedric | APLS | Common Stock | D | 384,292 | 714,288 | ||||||
| 2018-05-09 | 2018-05-07 | 4 | Grossi Federico | APLS | Common Stock | D | 7,706 | 16,206 | ||||||
| 2018-05-09 | 2018-05-07 | 4 | Machiels Alec Held by spouse | APLS | Common Stock | I | 930 | 930 | ||||||
| 2018-05-09 | 2018-05-07 | 4 | Machiels Alec | APLS | Common Stock | D | 288,219 | 669,544 | ||||||
| 2018-04-17 | 3 | SCHEIBLER LUKAS | APLS | No securities are beneficially owned | D | 0 | ||||||||
| 2018-04-17 | 2018-04-13 | 4 | SCHEIBLER LUKAS | APLS | Stock Option (right to buy) | D | 26.73 | 145,000 | 145,000 | |||||
| 2018-04-12 | 2018-04-11 | 4 | Grossi Federico | APLS | Stock Option (right to buy) | D | 3.20 | -8,500 | 61,823 | |||||
| 2018-04-12 | 2018-04-11 | 4 | Grossi Federico | APLS | Common Stock | D | 3.2000 | 8,500 | 27 | 8,500 | ||||
| 2018-02-21 | 2018-02-20 | 4 | Axon Steven | APLS | Stock Option (right to buy) | D | 2.59 | 38,610 | 359,889 | |||||
| 2018-02-21 | 2018-02-20 | 4 | Axon Steven | APLS | Common Stock | D | 2.5900 | 38,610 | 100 | 38,610 | ||||
| 2018-02-21 | 2018-02-16 | 4 | Axon Steven | APLS | Stock Option (right to buy) | D | 14.95 | 60,000 | 60,000 | |||||
| 2018-02-21 | 2018-02-16 | 4 | Francois Cedric | APLS | Stock Option (right to buy) | D | 14.95 | 280,000 | 280,000 | |||||
| 2018-02-21 | 2018-02-16 | 4 | Watson David O. | APLS | Stock Option (right to buy) | D | 14.95 | 25,000 | 25,000 | |||||
| 2018-02-21 | 2018-02-16 | 4 | Grossi Federico | APLS | Stock Option (right to buy) | D | 14.95 | 200,000 | 200,000 | |||||
| 2018-02-21 | 2018-02-16 | 4 | Perry Nicole D | APLS | Stock Option (right to buy) | D | 14.95 | 25,000 | 25,000 | |||||
| 2018-02-21 | 2018-02-16 | 4 | Sullivan Timothy Eugene | APLS | Stock Option (right to buy) | D | 14.95 | 25,000 | 25,000 | |||||
| 2018-02-21 | 2018-02-16 | 4 | Deschatelets Pascal | APLS | Stock Option (right to buy) | D | 14.95 | 110,000 | 110,000 | |||||
| 2017-11-15 | 2017-11-13 | 4 | Hillhouse Capital Management, Ltd. See footnotes | APLS | Series D Convertible Preferred Stock | I | 4,476,275 | 0 | ||||||
| 2017-11-15 | 2017-11-13 | 4 | Hillhouse Capital Management, Ltd. See footnotes | APLS | Common Stock | I | 14.0000 | 1,428,571 | 20,000 | 3,527,152 | ||||
| 2017-11-15 | 2017-11-13 | 4 | Hillhouse Capital Management, Ltd. See footnotes | APLS | Common Stock | I | 2,098,581 | 2,098,581 | ||||||
| 2017-11-14 | 2017-11-13 | 4 | Cormorant Asset Management, LLC | APLS | Series E Convertible Preferred Stock | D | -303,916 | 0 | ||||||
| 2017-11-14 | 2017-11-13 | 4 | Cormorant Asset Management, LLC | APLS | Series D Convertible Preferred Stock | D | -2,098,581 | 0 | ||||||
| 2017-11-14 | 2017-11-13 | 4 | Cormorant Asset Management, LLC | APLS | Common Stock | D | 14.0000 | 1,071,428 | 15,000 | 3,473,925 | ||||
| 2017-11-14 | 2017-11-13 | 4 | Cormorant Asset Management, LLC | APLS | Common Stock | D | 2,402,497 | 2,402,497 | ||||||
| 2017-11-13 | 2017-11-13 | 4 | GELLERT MICHAEL E | APLS | Series C Preferred Stock | D | -556,830 | 0 | ||||||
| 2017-11-13 | 2017-11-13 | 4 | GELLERT MICHAEL E | APLS | Series B Preferred Stock | D | -545,454 | 0 | ||||||
| 2017-11-13 | 2017-11-13 | 4 | GELLERT MICHAEL E | APLS | Series A Preferred Stock | D | -600,000 | 0 | ||||||
| 2017-11-13 | 2017-11-13 | 4 | GELLERT MICHAEL E | APLS | Common Stock | D | 798,068 | 943,989 | ||||||
| 2017-11-13 | 2017-11-13 | 4 | Morningside Venture Investments Ltd | APLS | Series E Preferred Stock | D | -259,302 | 0 | ||||||
| 2017-11-13 | 2017-11-13 | 4 | Morningside Venture Investments Ltd | APLS | Series D Preferred Stock | D | -4,476,275 | 0 | ||||||
| 2017-11-13 | 2017-11-13 | 4 | Morningside Venture Investments Ltd | APLS | Series C Preferred Stock | D | -17,200,000 | 0 | ||||||
| 2017-11-13 | 2017-11-13 | 4 | Morningside Venture Investments Ltd | APLS | Series B Preferred Stock | D | -1,054,544 | 0 | ||||||
| 2017-11-13 | 2017-11-13 | 4 | Morningside Venture Investments Ltd | APLS | Common Stock | D | 14.0000 | 575,000 | 8,050 | 11,353,303 | ||||
| 2017-11-13 | 2017-11-13 | 4 | Morningside Venture Investments Ltd | APLS | Common Stock | D | 10,778,303 | 10,778,303 | ||||||
| 2017-11-13 | 2017-11-13 | 4 | venBio Global Strategic Fund II L.P. | APLS | Series E Preferred Stock | D | -648,256 | 0 | ||||||
| 2017-11-13 | 2017-11-13 | 4 | venBio Global Strategic Fund II L.P. | APLS | Series D Preferred Stock | D | -6,714,413 | 0 | ||||||
| 2017-11-13 | 2017-11-13 | 4 | venBio Global Strategic Fund II L.P. | APLS | Common Stock | D | 14.0000 | 127,515 | 1,785 | 3,579,305 | ||||
| 2017-11-13 | 2017-11-13 | 4 | venBio Global Strategic Fund II L.P. | APLS | Common Stock | D | 3,451,790 | 3,451,790 | ||||||
| 2017-11-13 | 2017-11-13 | 4 | AJU IB Investment Co., Ltd. | APLS | Series D Preferred Stock | I | -888,969 | 0 | ||||||
| 2017-11-13 | 2017-11-13 | 4 | AJU IB Investment Co., Ltd. | APLS | Series C Preferred Stock | I | -4,000,000 | 0 | ||||||
| 2017-11-13 | 2017-11-13 | 4 | AJU IB Investment Co., Ltd. | APLS | Common Stock | I | 2,292,062 | 2,292,062 | ||||||
| 2017-11-13 | 2017-11-13 | 4 | Dunlop A. Sinclair | APLS | Series E Preferred Stock | I | -6,078 | 0 | ||||||
| 2017-11-13 | 2017-11-13 | 4 | Dunlop A. Sinclair | APLS | Series D Preferred Stock | I | -31,478 | 0 | ||||||
| 2017-11-13 | 2017-11-13 | 4 | Dunlop A. Sinclair | APLS | Series C Preferred Stock | I | -150,023 | 0 | ||||||
| 2017-11-13 | 2017-11-13 | 4 | Dunlop A. Sinclair | APLS | Series B Preferred Stock | I | -213,100 | 0 | ||||||
| 2017-11-13 | 2017-11-13 | 4 | Dunlop A. Sinclair | APLS | Common Stock | I | 400,679 | 400,679 | ||||||
| 2017-11-08 | 3 | GELLERT MICHAEL E | APLS | Common Stock | D | 291,842 | ||||||||
| 2017-11-08 | 3 | GELLERT MICHAEL E | APLS | Common Stock | D | 291,842 | ||||||||
| 2017-11-08 | 3 | Dunlop A. Sinclair | APLS | Common Stock | I | 372,742 | ||||||||
| 2017-11-08 | 3 | Dunlop A. Sinclair | APLS | Common Stock | I | 372,742 | ||||||||
| 2017-11-08 | 3 | Deschatelets Pascal | APLS | Common Stock | D | 1,122,904 | ||||||||
| 2017-11-08 | 3 | Deschatelets Pascal | APLS | Common Stock | D | 1,122,904 | ||||||||
| 2017-11-08 | 3 | Watson David O. | APLS | Common Stock | I | 18,752 | ||||||||
| 2017-11-08 | 3 | Watson David O. | APLS | Common Stock | I | 18,752 | ||||||||
| 2017-11-08 | 3 | Potentia Holdings, LLC | APLS | Common Stock | D | 7,653,202 | ||||||||
| 2017-11-08 | 3 | Potentia Holdings, LLC | APLS | Common Stock | D | 7,653,202 | ||||||||
| 2017-11-08 | 3 | Francois Cedric | APLS | Common Stock | I | 798,818 | ||||||||
| 2017-11-08 | 3 | Francois Cedric | APLS | Common Stock | I | 798,818 | ||||||||
| 2017-11-08 | 3 | Francois Cedric | APLS | Common Stock | D | 894,403 | ||||||||
| 2017-11-08 | 3 | Francois Cedric | APLS | Common Stock | D | 894,403 | ||||||||
| 2017-11-08 | 3 | Machiels Alec | APLS | Common Stock | D | 762,650 | ||||||||
| 2017-11-08 | 3 | Machiels Alec | APLS | Common Stock | D | 762,650 |
P
Pembelian sekuritas non-derivatif atau derivatif di pasar terbuka atau secara pribadi.
S
Penjualan terbuka atau penjualan pribadi atas sekuritas non-derivatif atau derivatif.
A
Hibah, penghargaan, atau perolehan sekuritas lainnya dari perusahaan (seperti opsi)
C
Konversi turunan
D
Penjualan atau pengalihan sekuritas kembali ke perusahaan.
F
Pembayaran harga pelaksanaan atau kewajiban pajak menggunakan sebagian sekuritas yang diterima dari perusahaan.
G
Pemberian sekuritas oleh atau kepada orang dalam.
K
Swap ekuitas dan transaksi lindung nilai serupa
M
Pelaksanaan atau konversi sekuritas derivatif yang diterima dari perusahaan (seperti opsi)
V
Transaksi yang dilaporkan secara sukarela pada Formulir 4.
J
Lainnya (disertai dengan catatan kaki yang menjelaskan transaksi tersebut)
