| Jumlah Saham Beredar | 96,198,609 shares |
| Saham Orang Dalam | 7,628,942 shares |
| Kepemilikan oleh Orang Dalam | 7.93 % |
| Orang Dalam Sejati | 31 |
Skor Sentimen Orang Dalam
Skor Sentimen Orang Dalam mengidentifikasi perusahaan yang dibeli oleh orang dalam korporat.
Ini adalah hasil dari model kuantitatif multifaktor yang canggih yang mengidentifikasi perusahaan dengan tingkat akumulasi internal tertinggi. Model penilaian ini menggunakan kombinasi dari jumlah bersih orang dalam yang membeli dalam 90 hari sebelumnya, total saham yang dibeli sebagai persentase dari jumlah saham yang beredar, dan total saham yang dimiliki oleh orang dalam. Angka tersebut berkisar dari 0 hingga 100, dengan angka yang lebih tinggi menunjukkan tingkat akumulasi yang lebih tinggi dibandingkan dengan perusahaan sejenis, dan 50 adalah rata-rata.
Frekuensi Pembaruan: Setiap Hari
Skor Sentimen Petugas
Skor Sentimen Pejabat menemukan perusahaan yang dibeli oleh Pejabat Korporat.
Menurut definisi, Pejabat Korporasi adalah Orang Dalam Korporasi, tetapi tidak seperti beberapa Orang Dalam lainnya (Pemegang Saham 10% dan Anggota Dewan), Pejabat bekerja untuk perusahaan setiap hari, dan mereka menggunakan uang mereka sendiri saat bertransaksi . (Pemegang Saham 10% dan Anggota Dewan seringkali adalah manajer dana yang mengelola uang orang lain.) Dengan demikian, transaksi orang dalam yang dilakukan oleh Pejabat jauh lebih signifikan dan harus ditangani dengan tepat.
Seperti Skor Sentimen Internal, Skor Sentimen Pejabat adalah hasil dari model kuantitatif multi-faktor yang canggih yang mengidentifikasi perusahaan dengan tingkat akumulasi pejabat tertinggi.
Frekuensi Pembaruan: Setiap Hari
Metrik Utama Orang Dalam
Kartu ini menunjukkan peringkat perusahaan berdasarkan berbagai metrik internal. Peringkat persentil menunjukkan bagaimana perusahaan ini dibandingkan dengan perusahaan lain di pasar AS. Peringkat yang lebih tinggi menunjukkan situasi yang lebih baik.
Sebagai contoh, secara umum diterima bahwa pembelian oleh orang dalam perusahaan adalah indikator positif, sehingga perusahaan dengan lebih banyak pembelian oleh orang dalam akan mendapat peringkat lebih tinggi daripada perusahaan dengan lebih sedikit pembelian oleh orang dalam (atau bahkan penjualan oleh orang dalam).
Jumlah Bersih Pembelian oleh Orang Dalam (Peringkat)
-1 ( )
9993 out of 11305Jumlah Bersih Pembelian oleh Orang Dalam adalah total jumlah orang dalam yang membeli dikurangi total jumlah orang dalam yang menjual dalam 90 hari terakhir. Peringkat persentil ditunjukkan di sini (kisaran dari 0 hingga 100%).
Persentase Saham yang Dibeli oleh Orang Dalam (Peringkat)
-0.003 %( )
9739 out of 11224Persentase Saham yang Dibeli oleh Orang Dalam adalah total jumlah saham yang dibeli oleh orang dalam dikurangi total jumlah saham yang dijual oleh orang dalam dalam 90 hari terakhir, dibagi dengan total jumlah saham yang beredar dan dikalikan dengan 100.
Grafik Perdagangan Orang Dalam
Grafik berikut menunjukkan Ultragenyx Pharmaceutical Inc. transaksi orang dalam. Orang dalam adalah pejabat, direktur, atau investor signifikan dalam suatu perusahaan. Secara umum, melakukan transaksi di perusahaan mereka berdasarkan informasi material yang belum dipublikasikan adalah ilegal bagi orang dalam. Ini tidak berarti bahwa mereka dilarang melakukan transaksi apa pun di perusahaan mereka sendiri. Namun, mereka wajib melaporkan semua transaksi kepada SEC melalui Formulir 4.
Daftar Orang Dalam dan Metrik Profitabilitas
Tabel ini menampilkan daftar orang dalam yang diketahui, dan dibuat secara otomatis dari pengajuan yang diungkapkan kepada SEC. Selain nama, jabatan terbaru, dan sebutan direktur, pejabat, atau pemilik 10%, kami memberikan kepemilikan terbaru yang diungkapkan. Selain itu, jika memungkinkan, kami memberikan kinerja perdagangan historis untuk orang dalam tersebut. Kinerja perdagangan historis adalah rata-rata tertimbang dari kinerja transaksi pembelian pasar terbuka aktual yang dilakukan oleh orang dalam tersebut. Untuk informasi lebih lanjut tentang bagaimana ini dihitung, tonton webinar YouTube ini.
See our leaderboard of most profitable insider traders.
| Orang Dalam | Rata-rata Keuntungan (%) | Saham Dimiliki |
Terbagi Disesuaikan |
|---|---|---|---|
| Sunil Agarwal Chief Medical Officer - [O] | 9,136 | 9,136 | |
| William Aliski Director - [D] | 66,849 | 66,849 | |
|
David Bonderman
10% Owner -
|
2,596,420 | 2,596,420 | |
| Camille L Bedrosian EVP and Chief Medical Officer - [O] | 46,720 | 46,720 | |
|
James G Coulter
10% Owner -
|
2,596,420 | 2,596,420 | |
| Eric Crombez EVP and Chief Medical Officer - [O] | 71,530 | 71,530 | |
| Jayson Donald Alexander Dallas EVP & Chief Commercial Officer - [O] | 23,830 | 23,830 | |
| Mardi Dier CFO & Executive Vice President - [O] | 66,695 | 66,695 | |
| Deborah Dunsire Director - [D] | 30,815 | 30,815 | |
| Lars Ekman Director - [D] | 17,745 | 17,745 |
| Orang Dalam | Rata-rata Keuntungan (%) | Saham Dimiliki |
Terbagi Disesuaikan |
|---|---|---|---|
| FMR LLC / Fidelity Management & Research - | 1,457,994 | 1,457,994 | |
| Matthew K Fust Director - [D] | 25,945 | 25,945 | |
| Erik Harris EVP & Chief Commercial Officer - [O] | 87,855 | 87,855 | |
| Wladimir Hogenhuis Chief Operating Officer - [O] | 18,703 | 18,703 | |
| Howard Horn Chief Financial Officer - [O] | 106,169 | 106,169 | |
| Dennis Karl Huang See Remarks - [O] | 114,591 | 114,591 | |
| Theodore Alan Huizenga SVP, Chief Accounting Officer - [O] | 50,124 | 50,124 | |
| Emil D Kakkis President & CEO, Director - [D] [O] | 2,158,985 | 2,158,985 | |
| Thomas Richard Kassberg CBO & EVP - [O] | 264,730 | 264,730 | |
| Michael Narachi Director - [D] | 32,690 | 32,690 |
| Orang Dalam | Rata-rata Keuntungan (%) | Saham Dimiliki |
Terbagi Disesuaikan |
|---|---|---|---|
| Eran Nadav Director - [D] | 0 | 0 | |
| Karah Herdman Parschauer EVP and Chief Legal Officer - [O] | 75,287 | 75,287 | |
| John Richard Pinion See Remarks - [O] | 108,428 | 108,428 | |
| Amrit Ray Director - [D] | 23,365 | 23,365 | |
| Clay B Siegall Director - [D] | 2,550 | 2,550 | |
| Shehnaaz Suliman Director - [D] | 25,940 | 25,940 | |
| Sanders Corazon (Corsee) D. Director - [D] | 15,344 | 15,344 | |
| Shalini Sharp EVP, Finance - [O] | 97,812 | 97,812 | |
| Marten Steen | 17,500 | ||
| TPG Group Holdings (SBS) Advisors, Inc. - | 2,596,420 | 2,596,420 | |
| Daniel G Welch Director - [D] | 32,690 | 32,690 |
Report errors via our new Insider Auditing Tool
Rekam Jejak Pembelian Orang Dalam - Analisis Keuntungan Jangka Pendek
Pada bagian ini, kami menganalisis profitabilitas setiap pembelian saham oleh orang dalam di pasar terbuka yang tidak direncanakan yang dilakukan di RARE / Ultragenyx Pharmaceutical Inc.. Analisis ini membantu memahami apakah orang dalam tersebut secara konsisten menghasilkan pengembalian abnormal, dan layak untuk diikuti. Analisis ini dilakukan selama satu tahun setelah setiap transaksi, dan hasilnya bersifat teoretis .
Tabel berikut menunjukkan pembelian pasar terbuka terbaru yang bukan bagian dari rencana perdagangan otomatis.
Harga yang Disesuaikan adalah harga yang disesuaikan dengan pemisahan saham. Ang Adjusted Shares ay ang jumlah saham yang disesuaikan dengan pemisahan saham (stock split).
Rekam Jejak Penjualan Orang Dalam - Analisis Kerugian Jangka Pendek
Dalam bagian ini, kami menganalisis penghindaran kerugian jangka pendek dari setiap penjualan dalam pasar terbuka yang tidak direncanakan oleh orang dalam yang dilakukan di RARE / Ultragenyx Pharmaceutical Inc.. Pola penghindaran kerugian yang konsisten dapat menunjukkan bahwa transaksi penjualan di masa mendatang dapat memprediksi penurunan harga. Analisis ini berlaku untuk satu tahun setelah setiap perdagangan, dan hasilnya bersifat teoretis .
Tabel berikut menunjukkan penjualan pasar terbuka terbaru yang bukan bagian dari rencana perdagangan otomatis.
Harga yang Disesuaikan adalah harga yang disesuaikan dengan pemisahan saham. Ang Adjusted Shares ay ang jumlah saham yang disesuaikan dengan pemisahan saham (stock split).
Riwayat Transaksi
Klik ikon tautan untuk melihat riwayat transaksi lengkap. Transaksi yang dilaporkan sebagai bagian dari rencana perdagangan otomatis 10b5-1 akan memiliki tanda X di kolom yang bertanda 10b-5.
| Berkas Tanggal |
Perdagangan Tanggal |
Formulir | Orang Dalam | Ticker | Judul Keamanan | Kode | Langsung | Latihan Harga |
Satuan Harga |
Unit Diubah |
Nilai Diubah (1 ribu) |
Sisa Pilihan |
Sisa Saham |
|
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 2025-06-23 | 2025-06-20 | 4 | Sanders Corazon (Corsee) D. | RARE | Common Stock | D | 37.3900 | -2,405 | -90 | 15,344 | ||||
| 2025-05-19 | 2025-05-15 | 4 | Dunsire Deborah | RARE | Common Stock | D | 5,740 | 30,815 | ||||||
| 2025-05-19 | 2025-05-15 | 4 | Fust Matthew K | RARE | Common Stock | D | 5,740 | 25,945 | ||||||
| 2025-05-19 | 2025-05-15 | 4 | NARACHI MICHAEL | RARE | Common Stock | D | 5,740 | 32,690 | ||||||
| 2025-05-19 | 2025-05-15 | 4 | WELCH DANIEL G | RARE | Common Stock | D | 5,740 | 32,690 | ||||||
| 2025-05-19 | 2025-05-15 | 4 | SULIMAN SHEHNAAZ | RARE | Common Stock | D | 5,740 | 25,940 | ||||||
| 2025-05-19 | 2025-05-15 | 4 | Sanders Corazon (Corsee) D. | RARE | Common Stock | D | 5,740 | 17,749 | ||||||
| 2025-05-19 | 2025-05-15 | 4 | Ray Amrit | RARE | Common Stock | D | 5,740 | 23,365 | ||||||
| 2025-05-05 | 2025-05-05 | 4 | Crombez Eric | RARE | Common Stock | D | 39.2400 | -520 | -20 | 71,530 | ||||
| 2025-05-05 | 2025-04-21 | 4 | Crombez Eric | RARE | Common Stock | D | 35.1100 | -242 | -8 | 71,680 | ||||
| 2025-03-10 | 2025-03-06 | 4 | Horn Howard | RARE | Common Stock | D | 40.4000 | -1,785 | -72 | 106,169 | ||||
| 2025-03-04 | 2025-03-03 | 4 | Kassberg Thomas Richard | RARE | Common Stock | D | 42.9200 | -508 | -22 | 264,730 | ||||
| 2025-03-04 | 2025-03-03 | 4 | Kassberg Thomas Richard | RARE | Common Stock | D | 42.1000 | -6,028 | -254 | 265,238 | ||||
| 2025-03-04 | 2025-03-01 | 4 | Kassberg Thomas Richard | RARE | Common Stock | D | 18,443 | 271,266 | ||||||
| 2025-03-04 | 2025-03-03 | 4 | Parschauer Karah Herdman | RARE | Common Stock | D | 42.1000 | -12,846 | -541 | 75,287 | ||||
| 2025-03-04 | 2025-03-01 | 4 | Parschauer Karah Herdman | RARE | Common Stock | D | 18,443 | 88,133 | ||||||
| 2025-03-04 | 2025-03-03 | 4 | Crombez Eric | RARE | Common Stock | D | 42.1000 | -8,945 | -377 | 71,922 | ||||
| 2025-03-04 | 2025-03-01 | 4 | Crombez Eric | RARE | Common Stock | D | 14,971 | 80,215 | ||||||
| 2025-03-04 | 2025-03-01 | 4 | Crombez Eric | RARE | Common Stock | D | 16,813 | 65,244 | ||||||
| 2025-03-04 | 2025-03-03 | 4 | Pinion John Richard | RARE | Common Stock | D | 42.9200 | -31 | -1 | 108,428 | ||||
| 2025-03-04 | 2025-03-03 | 4 | Pinion John Richard | RARE | Common Stock | D | 42.1000 | -14,439 | -608 | 107,766 | ||||
| 2025-03-04 | 2025-03-01 | 4 | Pinion John Richard | RARE | Common Stock | D | 18,443 | 122,205 | ||||||
| 2025-03-04 | 2025-03-01 | 4 | Pinion John Richard | RARE | Common Stock | D | 14,494 | 103,762 | ||||||
| 2025-03-04 | 2025-03-03 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 42.1000 | -73,434 | -3,092 | 641,731 | ||||
| 2025-03-04 | 2025-03-01 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 107,292 | 715,165 | ||||||
| 2025-03-04 | 2025-03-01 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 43,268 | 607,873 | ||||||
| 2025-03-04 | 2025-02-28 | 4 | KAKKIS EMIL D By Emil Kakkis and Jenny Soriano Living Trust, dated June 18, 2009 | RARE | Common Stock | I | 42.4800 | -25,000 | -1,062 | 2,158,985 | ||||
| 2025-03-04 | 2025-03-03 | 4 | Harris Erik | RARE | Common Stock | D | 42.1000 | -15,103 | -636 | 87,855 | ||||
| 2025-03-04 | 2025-03-01 | 4 | Harris Erik | RARE | Common Stock | D | 18,443 | 102,419 | ||||||
| 2025-03-04 | 2025-03-01 | 4 | Harris Erik | RARE | Common Stock | D | 16,813 | 83,976 | ||||||
| 2025-03-04 | 2025-03-03 | 4 | Huang Dennis Karl | RARE | Common Stock | D | 42.9200 | -1,348 | -58 | 114,591 | ||||
| 2025-03-04 | 2025-03-01 | 4 | Huang Dennis Karl | RARE | Common Stock | D | 18,443 | 115,939 | ||||||
| 2025-03-04 | 2025-03-01 | 4 | Huang Dennis Karl | RARE | Common Stock | D | 14,494 | 97,496 | ||||||
| 2025-03-04 | 2025-03-03 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 42.9200 | -141 | -6 | 50,124 | ||||
| 2025-03-04 | 2025-03-03 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 42.1000 | -967 | -41 | 50,265 | ||||
| 2025-03-04 | 2025-03-01 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 9,392 | 51,232 | ||||||
| 2025-03-04 | 2025-03-01 | 4 | Horn Howard | RARE | Common Stock | D | 15,653 | 107,954 | ||||||
| 2025-03-03 | 2025-03-01 | 4 | Parschauer Karah Herdman | RARE | Common Stock | D | 14,494 | 69,690 | ||||||
| 2025-03-03 | 2025-02-27 | 4 | Parschauer Karah Herdman | RARE | Common Stock | D | 42.7500 | -760 | -32 | 54,991 | ||||
| 2025-03-03 | 2025-02-27 | 4 | Parschauer Karah Herdman | RARE | Common Stock | D | 42.9300 | -2,230 | -96 | 55,751 | ||||
| 2024-12-31 | 2024-12-30 | 4 | KAKKIS EMIL D By Emil Kakkis and Jenny Soriano Living Trust, dated June 18, 2009 | RARE | Common Stock | I | 42.2300 | -11,727 | -495 | 2,183,985 | ||||
| 2024-12-11 | 2024-12-10 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | -648 | 41,840 | ||||||
| 2024-12-11 | 2024-12-10 | 4 | KAKKIS EMIL D By Emil Kakkis and Jenny Soriano Living Trust, dated June 18, 2009 | RARE | Common Stock | I | 50.0000 | -8,273 | -414 | 2,195,712 | ||||
| 2024-12-11 | 2024-12-09 | 4 | KAKKIS EMIL D By Emil Kakkis and Jenny Soriano Living Trust, dated June 18, 2009 | RARE | Common Stock | I | -20,000 | 2,203,985 | ||||||
| 2024-10-11 | 2024-10-10 | 4 | Horn Howard | RARE | Common Stock | D | 52.7600 | -7,465 | -394 | 92,301 | ||||
| 2024-09-18 | 2024-09-16 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 700 | 42,251 | ||||||
| 2024-09-05 | 2024-09-03 | 4 | KAKKIS EMIL D See FN | RARE | Common Stock | I | 55.8500 | -20,000 | -1,117 | 2,223,985 | ||||
| 2024-09-05 | 2024-09-03 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 56.1900 | -91 | -5 | 41,551 | ||||
| 2024-08-07 | 2024-08-06 | 4 | KAKKIS EMIL D See FN | RARE | Common Stock | I | 50.1700 | -20,000 | -1,003 | 2,243,985 | ||||
| 2024-07-03 | 2024-07-02 | 4 | Sanders Corazon (Corsee) D. | RARE | Common Stock | D | 40.9800 | -584 | -24 | 12,009 | ||||
| 2024-06-20 | 2024-06-18 | 4 | Dunsire Deborah | RARE | Common Stock | D | 5,345 | 25,075 | ||||||
| 2024-06-20 | 2024-06-18 | 4 | Fust Matthew K | RARE | Common Stock | D | 5,345 | 20,205 | ||||||
| 2024-06-20 | 2024-06-18 | 4 | WELCH DANIEL G | RARE | Common Stock | D | 5,345 | 26,950 | ||||||
| 2024-06-20 | 2024-06-18 | 4 | NARACHI MICHAEL | RARE | Common Stock | D | 5,345 | 26,950 | ||||||
| 2024-06-20 | 2024-06-18 | 4 | Ray Amrit | RARE | Common Stock | D | 5,345 | 17,625 | ||||||
| 2024-06-20 | 2024-06-18 | 4 | Sanders Corazon (Corsee) D. | RARE | Common Stock | D | 5,345 | 12,593 | ||||||
| 2024-06-20 | 2024-06-18 | 4 | SULIMAN SHEHNAAZ | RARE | Common Stock | D | 5,345 | 20,200 | ||||||
| 2024-06-12 | 2024-06-12 | 4 | Parschauer Karah Herdman | RARE | Common Stock | D | 45.0000 | -9,806 | -441 | 57,981 | ||||
| 2024-06-10 | 2024-06-10 | 4 | Sanders Corazon (Corsee) D. | RARE | Common Stock | D | 41.1000 | -1,737 | -71 | 7,248 | ||||
| 2024-05-03 | 2024-05-02 | 4 | Crombez Eric | RARE | Common Stock | D | 43.6600 | -354 | -15 | 48,431 | ||||
| 2024-04-19 | 2024-04-18 | 4 | Crombez Eric | RARE | Common Stock | D | 44.1000 | -142 | -6 | 48,785 | ||||
| 2024-04-18 | 2024-04-16 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 42.3100 | -14 | -1 | 41,366 | ||||
| 2024-03-12 | 2024-03-11 | 4 | Kassberg Thomas Richard | RARE | Common Stock | D | 49.9300 | -11,509 | -575 | 252,823 | ||||
| 2024-03-11 | 2024-03-07 | 4 | Fust Matthew K | RARE | Common Stock | D | 50.8800 | -7,500 | -382 | 14,860 | ||||
| 2024-03-11 | 2024-03-07 | 4 | Fust Matthew K | RARE | Common Stock | D | 50.8500 | -2,145 | -109 | 22,360 | ||||
| 2024-03-11 | 2024-03-07 | 4 | Fust Matthew K | RARE | Common Stock | D | 50.8900 | -2,550 | -130 | 24,505 | ||||
| 2024-03-05 | 2024-03-01 | 4 | Horn Howard | RARE | Common Stock | D | 19,400 | 99,766 | ||||||
| 2024-03-05 | 2024-03-01 | 4 | Parschauer Karah Herdman | RARE | Common Stock | D | 53.7600 | -3,756 | -202 | 67,340 | ||||
| 2024-03-05 | 2024-03-01 | 4 | Parschauer Karah Herdman | RARE | Common Stock | D | 957 | 70,739 | ||||||
| 2024-03-05 | 2024-03-01 | 4 | Parschauer Karah Herdman | RARE | Common Stock | D | 17,800 | 69,782 | ||||||
| 2024-03-05 | 2024-03-01 | 4 | Kassberg Thomas Richard | RARE | Common Stock | D | 53.7600 | -1,011 | -54 | 264,332 | ||||
| 2024-03-05 | 2024-03-01 | 4 | Kassberg Thomas Richard | RARE | Common Stock | D | 53.6900 | -274 | -15 | 265,343 | ||||
| 2024-03-05 | 2024-03-01 | 4 | Kassberg Thomas Richard | RARE | Common Stock | D | 957 | 265,617 | ||||||
| 2024-03-05 | 2024-03-01 | 4 | Kassberg Thomas Richard | RARE | Common Stock | D | 17,800 | 264,660 | ||||||
| 2024-03-05 | 2024-03-01 | 4 | Huang Dennis Karl | RARE | Common Stock | D | 53.6900 | -470 | -25 | 83,002 | ||||
| 2024-03-05 | 2024-03-01 | 4 | Huang Dennis Karl | RARE | Common Stock | D | 957 | 83,472 | ||||||
| 2024-03-05 | 2024-03-01 | 4 | Huang Dennis Karl | RARE | Common Stock | D | 17,800 | 82,515 | ||||||
| 2024-03-05 | 2024-03-01 | 4 | Pinion John Richard | RARE | Common Stock | D | 53.7600 | -4,173 | -224 | 89,268 | ||||
| 2024-03-05 | 2024-03-01 | 4 | Pinion John Richard | RARE | Common Stock | D | 53.6900 | -60 | -3 | 93,441 | ||||
| 2024-03-05 | 2024-03-01 | 4 | Pinion John Richard | RARE | Common Stock | D | 957 | 93,501 | ||||||
| 2024-03-05 | 2024-03-01 | 4 | Pinion John Richard | RARE | Common Stock | D | 17,800 | 92,544 | ||||||
| 2024-03-05 | 2024-03-01 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 53.7600 | -341 | -18 | 41,380 | ||||
| 2024-03-05 | 2024-03-01 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 53.6900 | -121 | -6 | 41,721 | ||||
| 2024-03-05 | 2024-03-01 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 13,950 | 41,842 | ||||||
| 2024-03-05 | 2024-03-01 | 4 | Crombez Eric | RARE | Common Stock | D | 53.7600 | -1,238 | -67 | 48,927 | ||||
| 2024-03-05 | 2024-03-01 | 4 | Crombez Eric | RARE | Common Stock | D | 19,400 | 49,912 | ||||||
| 2024-03-05 | 2024-03-01 | 4 | Harris Erik | RARE | Common Stock | D | 53.7600 | -4,768 | -256 | 67,163 | ||||
| 2024-03-05 | 2024-03-01 | 4 | Harris Erik | RARE | Common Stock | D | 957 | 71,638 | ||||||
| 2024-03-05 | 2024-03-01 | 4 | Harris Erik | RARE | Common Stock | D | 19,400 | 70,681 | ||||||
| 2024-03-05 | 2024-03-01 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 3,132 | 563,913 | ||||||
| 2024-03-05 | 2024-03-01 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 53.6900 | -17,417 | -935 | 560,781 | ||||
| 2024-03-05 | 2024-03-01 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 38,428 | 578,198 | ||||||
| 2024-02-08 | 2024-02-07 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 45.0000 | -30,000 | -1,350 | 539,770 | ||||
| 2024-01-02 | 2023-12-29 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 47.8700 | -30,000 | -1,436 | 569,770 | ||||
| 2024-01-02 | 2024-01-02 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 21.0000 | 3,000 | 63 | 27,892 | ||||
| 2024-01-02 | 2023-12-20 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 1,000 | 24,614 | ||||||
| 2023-10-24 | 2023-10-23 | 4 | Kassberg Thomas Richard | RARE | Common Stock | D | 32.7800 | -39,878 | -1,307 | 246,860 | ||||
| 2023-10-24 | 2023-10-23 | 4 | Kassberg Thomas Richard | RARE | Common Stock | D | 6.8600 | 39,878 | 274 | 286,738 | ||||
| 2023-10-23 | 2023-10-19 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 33.5200 | -47,853 | -1,604 | 599,743 | ||||
| 2023-10-23 | 2023-10-19 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 6.8600 | 47,853 | 328 | 647,029 | ||||
| 2023-10-10 | 2023-10-09 | 4 | Horn Howard | RARE | Common Stock | D | 80,366 | 80,336 | ||||||
| 2023-09-11 | 2023-09-07 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 38.3400 | -163 | -6 | 23,614 | ||||
| 2023-09-11 | 2023-09-07 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 41.0000 | -2,000 | -82 | 23,777 | ||||
| 2023-09-11 | 2023-09-07 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 21.0000 | 2,000 | 42 | 25,777 | ||||
| 2023-09-06 | 2023-09-05 | 4 | Harris Erik | RARE | Common Stock | D | 37.9600 | -6,000 | -228 | 51,281 | ||||
| 2023-09-06 | 2023-09-01 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 38.2300 | -87 | -3 | 23,777 | ||||
| 2023-09-06 | 2023-09-01 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 37.0400 | -883 | -33 | 23,864 | ||||
| 2023-06-30 | 2023-06-30 | 4 | Sanders Corazon (Corsee) D. | RARE | Common Stock | D | 46.7600 | -585 | -27 | 8,985 | ||||
| 2023-06-21 | 2023-06-19 | 4 | Harris Erik | RARE | Common Stock | D | 48.2000 | -305 | -15 | 57,281 | ||||
| 2023-06-09 | 2023-06-07 | 4 | Ray Amrit | RARE | Common Stock | D | 3,860 | 12,280 | ||||||
| 2023-06-09 | 2023-06-07 | 4 | Fust Matthew K | RARE | Common Stock | D | 51.8200 | -3,300 | -171 | 27,055 | ||||
| 2023-06-09 | 2023-06-07 | 4 | Fust Matthew K | RARE | Common Stock | D | 3,860 | 30,355 | ||||||
| 2023-06-09 | 2023-06-08 | 4 | Sanders Corazon (Corsee) D. | RARE | Common Stock | D | 51.6500 | -1,485 | -77 | 9,570 | ||||
| 2023-06-09 | 2023-06-07 | 4 | Sanders Corazon (Corsee) D. | RARE | Common Stock | D | 3,860 | 11,055 | ||||||
| 2023-06-09 | 2023-06-07 | 4 | Dunsire Deborah | RARE | Common Stock | D | 3,860 | 19,730 | ||||||
| 2023-06-09 | 2023-06-07 | 4 | NARACHI MICHAEL | RARE | Common Stock | D | 3,860 | 21,605 | ||||||
| 2023-06-09 | 2023-06-07 | 4 | SULIMAN SHEHNAAZ | RARE | Common Stock | D | 3,860 | 14,855 | ||||||
| 2023-06-09 | 2023-06-07 | 4 | WELCH DANIEL G | RARE | Common Stock | D | 3,860 | 21,605 | ||||||
| 2023-05-19 | 2023-05-18 | 4 | Pinion John Richard | RARE | Common Stock | D | 50.0000 | -2,012 | -101 | 74,744 | ||||
| 2023-05-10 | 2023-05-09 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 21.0000 | 3,000 | 63 | 30,747 | ||||
| 2023-05-05 | 2023-05-04 | 4 | Parschauer Karah Herdman | RARE | Common Stock | D | 45.0000 | -4,378 | -197 | 51,982 | ||||
| 2023-05-02 | 2023-05-01 | 4 | Crombez Eric | RARE | Common Stock | D | 4,658 | 30,512 | ||||||
| 2023-05-02 | 3 | Crombez Eric | RARE | Common Stock | D | 25,854 | ||||||||
| 2023-04-18 | 2023-04-16 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 38.2000 | -181 | -7 | 27,520 | ||||
| 2023-04-18 | 2023-04-16 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 38.2000 | -14 | -1 | 27,701 | ||||
| 2023-03-03 | 2023-03-01 | 4 | Bedrosian Camille L | RARE | Common Stock | D | 45.2500 | -3,881 | -176 | 46,720 | ||||
| 2023-03-03 | 2023-03-01 | 4 | Bedrosian Camille L | RARE | Common Stock | D | 2,663 | 50,601 | ||||||
| 2023-03-03 | 2023-03-01 | 4 | Parschauer Karah Herdman | RARE | Common Stock | D | 45.2500 | -3,161 | -143 | 56,139 | ||||
| 2023-03-03 | 2023-03-01 | 4 | Parschauer Karah Herdman | RARE | Common Stock | D | 22,000 | 59,101 | ||||||
| 2023-03-03 | 2023-03-01 | 4 | Parschauer Karah Herdman | RARE | Common Stock | D | 2,663 | 37,101 | ||||||
| 2023-03-03 | 2023-03-01 | 4 | Kassberg Thomas Richard | RARE | Common Stock | D | 45.6500 | -3,394 | -155 | 246,860 | ||||
| 2023-03-03 | 2023-03-01 | 4 | Kassberg Thomas Richard | RARE | Common Stock | D | 45.2700 | -1,968 | -89 | 250,254 | ||||
| 2023-03-03 | 2023-03-01 | 4 | Kassberg Thomas Richard | RARE | Common Stock | D | 22,000 | 252,222 | ||||||
| 2023-03-03 | 2023-03-01 | 4 | Kassberg Thomas Richard | RARE | Common Stock | D | 2,663 | 230,222 | ||||||
| 2023-03-03 | 2023-03-01 | 4 | Huang Dennis Karl | RARE | Common Stock | D | 45.6500 | -10,599 | -484 | 64,715 | ||||
| 2023-03-03 | 2023-03-01 | 4 | Huang Dennis Karl | RARE | Common Stock | D | 45.6500 | -389 | -18 | 75,314 | ||||
| 2023-03-03 | 2023-03-01 | 4 | Huang Dennis Karl | RARE | Common Stock | D | 22,000 | 75,703 | ||||||
| 2023-03-03 | 2023-03-01 | 4 | Huang Dennis Karl | RARE | Common Stock | D | 2,663 | 53,703 | ||||||
| 2023-03-03 | 2023-03-01 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 45.6500 | -1,333 | -61 | 21,715 | ||||
| 2023-03-03 | 2023-03-01 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 45.6500 | -100 | -5 | 23,048 | ||||
| 2023-03-03 | 2023-03-01 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 7,590 | 23,148 | ||||||
| 2023-03-03 | 2023-03-01 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 45.6500 | -16,140 | -737 | 599,176 | ||||
| 2023-03-03 | 2023-03-01 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 46,200 | 615,606 | ||||||
| 2023-03-03 | 2023-03-01 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 8,716 | 569,406 | ||||||
| 2023-03-03 | 2023-03-01 | 4 | Pinion John Richard | RARE | Common Stock | D | 45.6500 | -4,014 | -183 | 76,160 | ||||
| 2023-03-03 | 2023-03-01 | 4 | Pinion John Richard | RARE | Common Stock | D | 45.2600 | -3,755 | -170 | 80,174 | ||||
| 2023-03-03 | 2023-03-01 | 4 | Pinion John Richard | RARE | Common Stock | D | 22,000 | 83,929 | ||||||
| 2023-03-03 | 2023-03-01 | 4 | Pinion John Richard | RARE | Common Stock | D | 2,663 | 61,929 | ||||||
| 2023-03-03 | 2023-03-01 | 4 | Harris Erik | RARE | Common Stock | D | 45.2500 | -3,664 | -166 | 57,344 | ||||
| 2023-03-03 | 2023-03-01 | 4 | Harris Erik | RARE | Common Stock | D | 22,000 | 60,823 | ||||||
| 2023-03-03 | 2023-03-01 | 4 | Harris Erik | RARE | Common Stock | D | 2,663 | 38,823 | ||||||
| 2023-03-02 | 2023-02-28 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 43.4000 | -639 | -28 | 15,558 | ||||
| 2023-01-03 | 2022-12-30 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 45.5700 | -19,582 | -892 | 541,108 | ||||
| 2022-12-22 | 2022-12-21 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 43.9600 | -2,031 | -89 | 16,197 | ||||
| 2022-10-17 | 2022-10-14 | 4 | Dier Mardi | RARE | Common Stock | D | 40.1600 | -1,629 | -65 | 66,695 | ||||
| 2022-10-14 | 2022-10-12 | 4 | Dier Mardi | RARE | Common Stock | D | 38.2200 | -3,484 | -133 | 68,324 | ||||
| 2022-09-19 | 2022-09-16 | 4 | Dier Mardi | RARE | Common Stock | D | 20,000 | 71,808 | ||||||
| 2022-09-08 | 2022-09-01 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 1,000 | 18,094 | ||||||
| 2022-06-29 | 2022-06-24 | 4 | Sanders Corazon (Corsee) D. | RARE | Common Stock | D | 3,300 | 7,195 | ||||||
| 2022-06-28 | 2022-06-24 | 4 | WELCH DANIEL G | RARE | Common Stock | D | 3,300 | 17,745 | ||||||
| 2022-06-28 | 2022-06-24 | 4 | Ekman Lars | RARE | Common Stock | D | 3,300 | 17,745 | ||||||
| 2022-06-28 | 2022-06-24 | 4 | Fust Matthew K | RARE | Common Stock | D | 3,300 | 26,495 | ||||||
| 2022-06-28 | 2022-06-24 | 4 | NARACHI MICHAEL | RARE | Common Stock | D | 3,300 | 17,745 | ||||||
| 2022-06-28 | 2022-06-24 | 4 | Ray Amrit | RARE | Common Stock | D | 3,300 | 8,420 | ||||||
| 2022-06-28 | 2022-06-24 | 4 | Dunsire Deborah | RARE | Common Stock | D | 3,300 | 15,870 | ||||||
| 2022-06-28 | 2022-06-24 | 4 | SULIMAN SHEHNAAZ | RARE | Common Stock | D | 3,300 | 10,995 | ||||||
| 2022-06-22 | 2022-06-19 | 4 | Harris Erik | RARE | Common Stock | D | 54.7800 | -295 | -16 | 36,160 | ||||
| 2022-04-22 | 2022-04-19 | 4 | Ray Amrit | RARE | Stock Option (Right to Buy) | D | 78.10 | 9,525 | 9,525 | |||||
| 2022-04-22 | 2022-04-19 | 4 | Ray Amrit | RARE | Common Stock | D | 5,120 | 5,120 | ||||||
| 2022-04-19 | 2022-04-16 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 84.5500 | -132 | -11 | 16,914 | ||||
| 2022-03-15 | 2022-03-11 | 4 | Kassberg Thomas Richard | RARE | Common Stock | D | 67.0100 | -10,281 | -689 | 227,559 | ||||
| 2022-03-08 | 2022-03-04 | 4 | Fust Matthew K | RARE | Stock Option (Right to Buy) | D | 40.37 | -7,500 | 0 | |||||
| 2022-03-08 | 2022-03-04 | 4 | Fust Matthew K | RARE | Common Stock | D | 40.3700 | 7,500 | 303 | 23,195 | ||||
| 2022-03-08 | 2022-03-07 | 4 | Parschauer Karah Herdman | RARE | Common Stock | D | 62.9500 | -5,140 | -324 | 34,438 | ||||
| 2022-03-03 | 2022-03-01 | 4 | Harris Erik | RARE | Stock Option (Right to Buy) | D | 67.37 | 24,900 | 24,900 | |||||
| 2022-03-03 | 2022-03-01 | 4 | Harris Erik | RARE | Common Stock | D | 14,000 | 36,317 | ||||||
| 2022-03-03 | 2022-03-01 | 4 | Harris Erik | RARE | Common Stock | D | 66.6200 | -2,713 | -181 | 22,317 | ||||
| 2022-03-03 | 2022-03-03 | 4 | Dier Mardi | RARE | Common Stock | D | 64.5500 | -420 | -27 | 51,808 | ||||
| 2022-03-03 | 2022-03-01 | 4 | Dier Mardi | RARE | Stock Option (Right to Buy) | D | 67.37 | 24,900 | 24,900 | |||||
| 2022-03-03 | 2022-03-01 | 4 | Dier Mardi | RARE | Common Stock | D | 14,000 | 52,228 | ||||||
| 2022-03-03 | 2022-03-01 | 4 | Dier Mardi | RARE | Common Stock | D | 66.6200 | -534 | -36 | 38,228 | ||||
| 2022-03-03 | 2022-03-01 | 4 | Pinion John Richard | RARE | Stock Option (Right to Buy) | D | 67.37 | 24,900 | 24,900 | |||||
| 2022-03-03 | 2022-03-01 | 4 | Pinion John Richard | RARE | Common Stock | D | 14,000 | 59,266 | ||||||
| 2022-03-03 | 2022-03-01 | 4 | Pinion John Richard | RARE | Common Stock | D | 66.6200 | -4,498 | -300 | 45,266 | ||||
| 2022-03-03 | 2022-03-01 | 4 | Huang Dennis Karl | RARE | Stock Option (Right to Buy) | D | 67.37 | 24,900 | 24,900 | |||||
| 2022-03-03 | 2022-03-01 | 4 | Huang Dennis Karl | RARE | Common Stock | D | 14,000 | 51,040 | ||||||
| 2022-03-03 | 2022-03-01 | 4 | Huang Dennis Karl | RARE | Common Stock | D | 66.6200 | -3,234 | -215 | 36,914 | ||||
| 2022-03-03 | 2022-03-01 | 4 | Huizenga Theodore Alan | RARE | Stock Option (Right to Buy) | D | 67.37 | 7,400 | 7,400 | |||||
| 2022-03-03 | 2022-03-01 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 3,710 | 17,046 | ||||||
| 2022-03-03 | 2022-03-01 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 66.6200 | -843 | -56 | 13,229 | ||||
| 2022-03-03 | 2022-03-01 | 4 | KAKKIS EMIL D | RARE | Stock Option (Right to Buy) | D | 67.37 | 92,360 | 92,360 | |||||
| 2022-03-03 | 2022-03-01 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 52,041 | 634,226 | ||||||
| 2022-03-03 | 2022-03-01 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 67.3700 | -12,162 | -819 | 582,185 | ||||
| 2022-03-03 | 2022-03-01 | 4 | Bedrosian Camille L | RARE | Stock Option (Right to Buy) | D | 67.37 | 24,900 | 24,900 | |||||
| 2022-03-03 | 2022-03-01 | 4 | Bedrosian Camille L | RARE | Common Stock | D | 14,000 | 47,938 | ||||||
| 2022-03-03 | 2022-03-01 | 4 | Bedrosian Camille L | RARE | Common Stock | D | 66.6200 | -2,821 | -188 | 33,938 | ||||
| 2022-03-03 | 2022-03-01 | 4 | Parschauer Karah Herdman | RARE | Stock Option (Right to Buy) | D | 67.37 | 24,900 | 24,900 | |||||
| 2022-03-03 | 2022-03-01 | 4 | Parschauer Karah Herdman | RARE | Common Stock | D | 14,000 | 39,578 | ||||||
| 2022-03-03 | 2022-03-01 | 4 | Parschauer Karah Herdman | RARE | Common Stock | D | 66.6200 | -2,886 | -192 | 25,472 | ||||
| 2022-03-03 | 2022-03-01 | 4 | Kassberg Thomas Richard | RARE | Stock Option (Right to Buy) | D | 67.37 | 24,900 | 24,900 | |||||
| 2022-03-03 | 2022-03-01 | 4 | Kassberg Thomas Richard | RARE | Common Stock | D | 14,000 | 227,840 | ||||||
| 2022-03-03 | 2022-03-01 | 4 | Kassberg Thomas Richard | RARE | Common Stock | D | 66.6200 | -2,374 | -158 | 213,840 | ||||
| 2022-02-01 | 2021-12-10 | 5 | Kassberg Thomas Richard | RARE | Common Stock | D | -52 | 216,214 | ||||||
| 2022-02-01 | 2021-12-10 | 5 | KAKKIS EMIL D By Emil Kakkis and Jenny Soriano Living Trust, dated June 18, 200 | RARE | Common Stock | I | -50,000 | 2,209,741 | ||||||
| 2022-02-01 | 2022-01-30 | 4 | Bedrosian Camille L | RARE | Common Stock | D | 66.3000 | -1,657 | -110 | 36,759 | ||||
| 2021-10-18 | 2021-10-14 | 4 | Bedrosian Camille L | RARE | Common Stock | D | 81.1400 | -359 | -29 | 38,416 | ||||
| 2021-10-18 | 2021-10-14 | 4 | Harris Erik | RARE | Common Stock | D | 81.1400 | -303 | -25 | 25,030 | ||||
| 2021-10-18 | 2021-10-14 | 4 | Huang Dennis Karl | RARE | Common Stock | D | 81.1400 | -358 | -29 | 40,148 | ||||
| 2021-10-18 | 2021-10-14 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 81.1400 | -140 | -11 | 14,072 | ||||
| 2021-10-18 | 2021-09-13 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | -819 | 14,212 | ||||||
| 2021-10-18 | 2021-10-14 | 4 | Kassberg Thomas Richard | RARE | Common Stock | D | 81.1400 | -286 | -23 | 216,266 | ||||
| 2021-10-18 | 2021-10-14 | 4 | Parschauer Karah Herdman | RARE | Common Stock | D | 81.1400 | -310 | -25 | 28,358 | ||||
| 2021-10-18 | 2021-10-14 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 81.0000 | -853 | -69 | 594,347 | ||||
| 2021-10-18 | 2021-10-14 | 4 | Pinion John Richard | RARE | Common Stock | D | 81.1400 | -358 | -29 | 49,764 | ||||
| 2021-10-14 | 2021-10-14 | 4 | Dier Mardi | RARE | Common Stock | D | 81.1600 | -3,261 | -265 | 38,762 | ||||
| 2021-10-14 | 2021-10-12 | 4 | Dier Mardi | RARE | Common Stock | D | 82.7900 | -3,477 | -288 | 42,023 | ||||
| 2021-10-01 | 2021-09-30 | 4 | Kassberg Thomas Richard | RARE | Stock Option (Right to Buy) | D | 0.31 | -109,734 | 0 | |||||
| 2021-10-01 | 2021-09-30 | 4 | Kassberg Thomas Richard | RARE | Common Stock | D | 0.3100 | 109,734 | 34 | 216,552 | ||||
| 2021-09-09 | 2021-09-08 | 4 | Parschauer Karah Herdman | RARE | Stock Option (Right to Buy) | D | 54.50 | -7,336 | 17,664 | |||||
| 2021-09-09 | 2021-09-08 | 4 | Parschauer Karah Herdman | RARE | Common Stock | D | 100.6500 | -7,336 | -738 | 28,668 | ||||
| 2021-09-09 | 2021-09-08 | 4 | Parschauer Karah Herdman | RARE | Common Stock | D | 54.5000 | 7,336 | 400 | 36,004 | ||||
| 2021-09-02 | 2021-09-02 | 4 | Bedrosian Camille L | RARE | Stock Option (Right to Buy) | D | 55.00 | -2,500 | 53,000 | |||||
| 2021-09-02 | 2021-09-02 | 4 | Bedrosian Camille L | RARE | Common Stock | D | 100.1800 | -2,500 | -250 | 38,775 | ||||
| 2021-09-02 | 2021-09-02 | 4 | Bedrosian Camille L | RARE | Common Stock | D | 55.0000 | 2,500 | 138 | 41,275 | ||||
| 2021-09-02 | 2021-09-01 | 4 | Bedrosian Camille L | RARE | Stock Option (Right to Buy) | D | 55.00 | -2,500 | 55,500 | |||||
| 2021-09-02 | 2021-09-01 | 4 | Bedrosian Camille L | RARE | Common Stock | D | 100.0300 | -2,500 | -250 | 38,775 | ||||
| 2021-09-02 | 2021-09-01 | 4 | Bedrosian Camille L | RARE | Common Stock | D | 55.0000 | 2,500 | 138 | 41,275 | ||||
| 2021-07-08 | 2021-07-06 | 4 | Harris Erik | RARE | Common Stock | D | 91.5300 | -375 | -34 | 25,333 | ||||
| 2021-06-30 | 2021-06-29 | 4 | Sanders Corazon (Corsee) D. | RARE | Stock Option (Right to Buy) | D | 96.29 | 7,255 | 7,255 | |||||
| 2021-06-30 | 2021-06-29 | 4 | Sanders Corazon (Corsee) D. | RARE | Common Stock | D | 3,895 | 3,895 | ||||||
| 2021-06-28 | 2021-06-24 | 4 | Dunsire Deborah | RARE | Stock Option (Right to Buy) | D | 93.20 | 4,125 | 4,125 | |||||
| 2021-06-28 | 2021-06-24 | 4 | Dunsire Deborah | RARE | Common stock | D | 2,145 | 12,570 | ||||||
| 2021-06-28 | 2021-06-24 | 4 | Aliski William | RARE | Stock Option (Right to Buy) | D | 93.20 | 4,125 | 4,125 | |||||
| 2021-06-28 | 2021-06-24 | 4 | Aliski William | RARE | Common Stock | D | 2,145 | 66,849 | ||||||
| 2021-06-28 | 2021-06-24 | 4 | WELCH DANIEL G | RARE | Stock Option (Right to Buy) | D | 93.20 | 4,125 | 4,125 | |||||
| 2021-06-28 | 2021-06-24 | 4 | WELCH DANIEL G | RARE | Common Stock | D | 2,145 | 14,445 | ||||||
| 2021-06-28 | 2021-06-24 | 4 | Ekman Lars | RARE | Stock Option (Right to Buy) | D | 93.20 | 4,125 | 4,125 | |||||
| 2021-06-28 | 2021-06-24 | 4 | Ekman Lars | RARE | Common Stock | D | 2,145 | 14,445 | ||||||
| 2021-06-28 | 2021-06-24 | 4 | NARACHI MICHAEL | RARE | Stock Option (Right to Buy) | D | 93.20 | 4,125 | 4,125 | |||||
| 2021-06-28 | 2021-06-24 | 4 | NARACHI MICHAEL | RARE | Common Stock | D | 2,145 | 14,445 | ||||||
| 2021-06-28 | 2021-06-24 | 4 | Fust Matthew K | RARE | Stock Option (Right to Buy) | D | 93.20 | 4,125 | 4,125 | |||||
| 2021-06-28 | 2021-06-24 | 4 | Fust Matthew K | RARE | Common Stock | D | 2,145 | 15,695 | ||||||
| 2021-06-28 | 2021-06-24 | 4 | SULIMAN SHEHNAAZ | RARE | Stock Option (Right to Buy) | D | 93.20 | 4,125 | 4,125 | |||||
| 2021-06-28 | 2021-06-24 | 4 | SULIMAN SHEHNAAZ | RARE | Common Stock | D | 2,145 | 7,695 | ||||||
| 2021-06-23 | 2021-06-21 | 4 | Harris Erik | RARE | Common Stock | D | 94.9600 | -572 | -54 | 25,708 | ||||
| 2021-06-23 | 2021-06-19 | 4 | Harris Erik | RARE | Common Stock | D | 94.6300 | -437 | -41 | 26,280 | ||||
| 2021-06-11 | 2021-06-10 | 4 | Parschauer Karah Herdman | RARE | Common Stock | D | 100.0000 | -1,329 | -133 | 28,668 | ||||
| 2021-05-10 | 2021-05-06 | 4 | Huang Dennis Karl | RARE | Common Stock | D | 113.6800 | -363 | -41 | 40,506 | ||||
| 2021-05-10 | 2021-05-06 | 4 | Pinion John Richard | RARE | Common Stock | D | 113.6900 | -363 | -41 | 50,122 | ||||
| 2021-05-10 | 2021-05-06 | 4 | Parschauer Karah Herdman | RARE | Common Stock | D | 113.6700 | -313 | -36 | 29,997 | ||||
| 2021-05-10 | 2021-05-06 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 113.6700 | -142 | -16 | 15,031 | ||||
| 2021-05-10 | 2021-05-06 | 4 | Kassberg Thomas Richard | RARE | Common Stock | D | 113.6900 | -363 | -41 | 106,818 | ||||
| 2021-05-10 | 2021-05-06 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 115.7100 | -852 | -99 | 595,200 | ||||
| 2021-05-10 | 2021-05-07 | 4 | Harris Erik | RARE | Common Stock | D | 113.6700 | -393 | -45 | 26,717 | ||||
| 2021-05-10 | 2021-05-06 | 4 | Harris Erik | RARE | Common Stock | D | 113.6800 | -307 | -35 | 27,110 | ||||
| 2021-05-10 | 2021-05-06 | 4 | Bedrosian Camille L | RARE | Common Stock | D | 113.6700 | -364 | -41 | 38,775 | ||||
| 2021-05-05 | 2021-05-03 | 4 | KAKKIS EMIL D By Emil Kakkis and Jenny Soriano Living Trust, dated June 18, 200 | RARE | Common Stock | I | 107.8000 | -30,000 | -3,234 | 2,259,741 | ||||
| 2021-04-21 | 2021-04-20 | 4 | Harris Erik | RARE | Common Stock | D | 104.2800 | -396 | -41 | 27,417 | ||||
| 2021-04-19 | 2021-04-15 | 4 | Bedrosian Camille L | RARE | Stock Option | D | 55.00 | -5,000 | 58,000 | |||||
| 2021-04-19 | 2021-04-15 | 4 | Bedrosian Camille L | RARE | Common Stock | D | 109.0900 | -5,000 | -545 | 39,139 | ||||
| 2021-04-19 | 2021-04-15 | 4 | Bedrosian Camille L | RARE | Common Stock | D | 55.0000 | 5,000 | 275 | 44,139 | ||||
| 2021-04-19 | 2021-04-16 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 1,500 | 15,044 | ||||||
| 2021-03-09 | 2021-03-08 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 120.6900 | -3,000 | -362 | 13,544 | ||||
| 2021-03-03 | 2021-03-01 | 4 | Kassberg Thomas Richard | RARE | Stock Option (Right to Buy) | D | 142.47 | 11,000 | 11,000 | |||||
| 2021-03-03 | 2021-03-01 | 4 | Kassberg Thomas Richard | RARE | Common Stock | D | 138.1700 | -4,572 | -632 | 107,181 | ||||
| 2021-03-03 | 2021-03-01 | 4 | Kassberg Thomas Richard | RARE | Common Stock | D | 4,636 | 111,614 | ||||||
| 2021-03-03 | 2021-03-01 | 4 | Kassberg Thomas Richard | RARE | Common Stock | D | 5,500 | 106,978 | ||||||
| 2021-03-03 | 2021-03-01 | 4 | Parschauer Karah Herdman | RARE | Stock Option (Right to Buy) | D | 142.47 | 11,000 | 11,000 | |||||
| 2021-03-03 | 2021-03-01 | 4 | Parschauer Karah Herdman | RARE | Common Stock | D | 138.1700 | -3,970 | -549 | 30,227 | ||||
| 2021-03-03 | 2021-03-01 | 4 | Parschauer Karah Herdman | RARE | Common Stock | D | 4,636 | 34,197 | ||||||
| 2021-03-03 | 2021-03-01 | 4 | Parschauer Karah Herdman | RARE | Common Stock | D | 5,500 | 29,561 | ||||||
| 2021-03-03 | 2021-03-01 | 4 | Pinion John Richard | RARE | Stock Option (Right to Buy) | D | 142.47 | 11,000 | 11,000 | |||||
| 2021-03-03 | 2021-03-01 | 4 | Pinion John Richard | RARE | Common Stock | D | 138.1700 | -6,198 | -856 | 50,237 | ||||
| 2021-03-03 | 2021-03-01 | 4 | Pinion John Richard | RARE | Common Stock | D | 4,636 | 56,435 | ||||||
| 2021-03-03 | 2021-03-01 | 4 | Pinion John Richard | RARE | Common Stock | D | 5,500 | 51,799 | ||||||
| 2021-03-03 | 2021-03-01 | 4 | Huizenga Theodore Alan | RARE | Stock Option (Right to Buy) | D | 142.47 | 4,655 | 4,655 | |||||
| 2021-03-03 | 2021-03-01 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 138.1700 | -732 | -101 | 16,544 | ||||
| 2021-03-03 | 2021-03-01 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 1,560 | 17,276 | ||||||
| 2021-03-03 | 2021-03-02 | 4 | Harris Erik | RARE | Common Stock | D | 138.1600 | -707 | -98 | 27,813 | ||||
| 2021-03-03 | 2021-03-01 | 4 | Harris Erik | RARE | Stock Option (Right to Buy) | D | 142.47 | 11,000 | 11,000 | |||||
| 2021-03-03 | 2021-03-01 | 4 | Harris Erik | RARE | Common Stock | D | 138.1700 | -2,470 | -341 | 28,520 | ||||
| 2021-03-03 | 2021-03-01 | 4 | Harris Erik | RARE | Common Stock | D | 4,636 | 30,990 | ||||||
| 2021-03-03 | 2021-03-01 | 4 | Harris Erik | RARE | Common Stock | D | 5,500 | 26,354 | ||||||
| 2021-03-03 | 2021-03-01 | 4 | Huang Dennis Karl | RARE | Stock Option (Right to Buy) | D | 142.47 | 11,000 | 11,000 | |||||
| 2021-03-03 | 2021-03-01 | 4 | Huang Dennis Karl | RARE | Common Stock | D | 138.1800 | -4,255 | -588 | 40,761 | ||||
| 2021-03-03 | 2021-03-01 | 4 | Huang Dennis Karl | RARE | Common Stock | D | 4,636 | 44,835 | ||||||
| 2021-03-03 | 2021-03-01 | 4 | Huang Dennis Karl | RARE | Common Stock | D | 5,500 | 40,199 | ||||||
| 2021-03-03 | 2021-03-01 | 4 | Dier Mardi | RARE | Stock Option (Right to Buy) | D | 142.47 | 11,000 | 11,000 | |||||
| 2021-03-03 | 2021-03-01 | 4 | Dier Mardi | RARE | Common Stock | D | 5,500 | 45,500 | ||||||
| 2021-03-03 | 2021-03-01 | 4 | Bedrosian Camille L | RARE | Stock Option (Right o Buy) | D | 142.47 | 11,000 | 11,000 | |||||
| 2021-03-03 | 2021-03-01 | 4 | Bedrosian Camille L | RARE | Common Stock | D | 138.1800 | -4,543 | -628 | 39,139 | ||||
| 2021-03-03 | 2021-03-01 | 4 | Bedrosian Camille L | RARE | Common Stock | D | 4,636 | 43,682 | ||||||
| 2021-03-03 | 2021-03-01 | 4 | Bedrosian Camille L | RARE | Common Stock | D | 5,500 | 39,046 | ||||||
| 2021-03-03 | 2021-03-01 | 4 | KAKKIS EMIL D | RARE | Stock Option (Right to Buy) | D | 142.47 | 36,000 | 36,000 | |||||
| 2021-03-03 | 2021-03-01 | 4 | KAKKIS EMIL D By Emil Kakkis and Jenny Soriano Living Trust, dated June 18, 2009 | RARE | Common Stock | I | 141.8000 | -30,000 | -4,254 | 2,289,741 | ||||
| 2021-03-03 | 2021-03-01 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 142.4700 | -16,342 | -2,328 | 596,052 | ||||
| 2021-03-03 | 2021-03-01 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 15,453 | 612,394 | ||||||
| 2021-03-03 | 2021-03-01 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 18,000 | 596,941 | ||||||
| 2021-02-23 | 2021-02-23 | 4 | Aliski William | RARE | Common Stock | D | -1,000 | 64,704 | ||||||
| 2021-02-23 | 2021-02-19 | 4 | Aliski William | RARE | Stock Option (Right to Buy) | D | 97.85 | -7,500 | 0 | |||||
| 2021-02-23 | 2021-02-19 | 4 | Aliski William | RARE | Common Stock | D | 149.0100 | -7,500 | -1,118 | 65,704 | ||||
| 2021-02-23 | 2021-02-19 | 4 | Aliski William | RARE | Common Stock | D | 97.8500 | 7,500 | 734 | 73,204 | ||||
| 2021-02-03 | 2020-11-06 | 5 | Huizenga Theodore Alan | RARE | Common Stock | D | -934 | 15,502 | ||||||
| 2021-02-03 | 2020-08-27 | 5 | Aliski William | RARE | Common Stock | D | -1,000 | 65,704 | ||||||
| 2021-02-03 | 2020-05-21 | 5 | Aliski William | RARE | Common Stock | D | -1,000 | 65,704 | ||||||
| 2021-02-03 | 2020-11-27 | 5 | KAKKIS EMIL D | RARE | Common Stock | D | -31,248 | 578,941 | ||||||
| 2021-02-03 | 2020-11-19 | 5 | KAKKIS EMIL D By Emil Kakkis and Jenny Soriano Living Trust, dated June 18, 2009 | RARE | Common Stock | I | -10,000 | 2,349,741 | ||||||
| 2021-02-03 | 2020-05-27 | 5 | KAKKIS EMIL D | RARE | Common Stock | D | -40,422 | 578,941 | ||||||
| 2021-02-03 | 2020-05-22 | 5 | KAKKIS EMIL D By Emil Kakkis and Jenny Soriano Living Trust, dated June 18, 2009 | RARE | Common Stock | I | -100,000 | 2,349,741 | ||||||
| 2021-02-03 | 2020-06-03 | 4 | Harris Erik | RARE | Common Stock | D | 74.6900 | -2,516 | -188 | 20,854 | ||||
| 2021-02-02 | 2021-01-30 | 4 | Bedrosian Camille L | RARE | Common Stock | D | 140.3600 | -2,243 | -315 | 33,546 | ||||
| 2021-01-19 | 2021-01-15 | 4 | Bedrosian Camille L | RARE | Stock Option (Right to Buy) | D | 55.00 | -25,000 | 63,000 | |||||
| 2021-01-19 | 2021-01-15 | 4 | Bedrosian Camille L | RARE | Common Stock | D | 139.1800 | -25,000 | -3,480 | 35,789 | ||||
| 2021-01-19 | 2021-01-15 | 4 | Bedrosian Camille L | RARE | Common Stock | D | 55.0000 | 25,000 | 1,375 | 60,789 | ||||
| 2021-01-08 | 2021-01-07 | 4 | Huizenga Theodore Alan | RARE | Stock Option | D | 21.00 | -4,000 | 8,000 | |||||
| 2021-01-08 | 2021-01-07 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 140.6500 | -4,000 | -563 | 15,716 | ||||
| 2021-01-08 | 2021-01-07 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 21.0000 | 4,000 | 84 | 20,436 | ||||
| 2021-01-05 | 2021-01-04 | 4 | KAKKIS EMIL D By Emil Kakkis and Jenny Soriano Living Trust, dated June 18, 2009 | RARE | Common Stock | I | 136.9000 | -30,000 | -4,107 | 2,329,741 | ||||
| 2020-11-04 | 2020-11-02 | 4 | KAKKIS EMIL D By Emil Kakkis and Jenny Soriano Living Trust, dated June 18, 2009 | RARE | Common Stock | I | 96.8200 | -30,000 | -2,905 | 2,359,741 | ||||
| 2020-11-02 | 2020-10-30 | 4 | Parschauer Karah Herdman | RARE | Stock Option (Right to Buy) | D | 54.50 | -9,903 | 25,000 | |||||
| 2020-11-02 | 2020-10-30 | 4 | Parschauer Karah Herdman | RARE | Common Stock | D | 100.1200 | -9,903 | -991 | 24,061 | ||||
| 2020-11-02 | 2020-10-30 | 4 | Parschauer Karah Herdman | RARE | Common Stock | D | 54.5000 | 9,903 | 540 | 33,871 | ||||
| 2020-10-30 | 2020-10-28 | 4 | Parschauer Karah Herdman | RARE | Stock Option (Right to Buy) | D | 54.50 | -97 | 34,903 | |||||
| 2020-10-30 | 2020-10-28 | 4 | Parschauer Karah Herdman | RARE | Common Stock | D | 100.0000 | -97 | -10 | 23,968 | ||||
| 2020-10-30 | 2020-10-28 | 4 | Parschauer Karah Herdman | RARE | Common Stock | D | 54.5000 | 97 | 5 | 24,065 | ||||
| 2020-10-16 | 2020-10-14 | 4 | Parschauer Karah Herdman | RARE | Common Stock | D | 88.0000 | -325 | -29 | 23,968 | ||||
| 2020-10-16 | 2020-10-14 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 92.6900 | -852 | -79 | 610,189 | ||||
| 2020-10-16 | 2020-10-14 | 4 | Bedrosian Camille L | RARE | Common Stock | D | 88.0000 | -262 | -23 | 35,789 | ||||
| 2020-10-16 | 2020-10-14 | 4 | Harris Erik | RARE | Common Stock | D | 88.0000 | -220 | -19 | 23,370 | ||||
| 2020-10-16 | 2020-10-14 | 4 | Kassberg Thomas Richard | RARE | Common Stock | D | 87.9800 | -262 | -23 | 101,478 | ||||
| 2020-10-16 | 2020-10-14 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 87.9800 | -146 | -13 | 16,436 | ||||
| 2020-10-16 | 2020-10-14 | 4 | Huang Dennis Karl | RARE | Common Stock | D | 88.0000 | -262 | -23 | 34,699 | ||||
| 2020-10-16 | 2020-10-14 | 4 | Pinion John Richard | RARE | Common Stock | D | 88.0000 | -262 | -23 | 46,299 | ||||
| 2020-10-16 | 2020-10-14 | 4 | Sharp Shalini | RARE | Common Stock | D | 87.9900 | -375 | -33 | 97,812 | ||||
| 2020-10-13 | 2020-10-12 | 4 | Pinion John Richard | RARE | Common Stock | D | 94.4700 | -2,780 | -263 | 46,561 | ||||
| 2020-10-13 | 2020-10-08 | 4 | Parschauer Karah Herdman | RARE | Stock Option (Right to Buy) | D | 54.50 | -10,000 | 35,000 | |||||
| 2020-10-13 | 2020-10-08 | 4 | Parschauer Karah Herdman | RARE | Common Stock | D | 95.0000 | -10,000 | -950 | 24,293 | ||||
| 2020-10-13 | 2020-10-08 | 4 | Parschauer Karah Herdman | RARE | Common Stock | D | 54.5000 | 10,000 | 545 | 34,293 | ||||
| 2020-10-13 | 2020-10-12 | 4 | Dier Mardi | RARE | Stock Option (Right to Buy) | D | 95.50 | 40,000 | 40,000 | |||||
| 2020-10-13 | 2020-10-12 | 4 | Dier Mardi | RARE | Common Stock | D | 40,000 | 40,000 | ||||||
| 2020-10-07 | 2020-10-06 | 4 | Parschauer Karah Herdman | RARE | Stock Option (Right to Buy) | D | 48.43 | -10,000 | 17,000 | |||||
| 2020-10-07 | 2020-10-06 | 4 | Parschauer Karah Herdman | RARE | Common Stock | D | 90.0000 | -10,000 | -900 | 24,293 | ||||
| 2020-10-07 | 2020-10-06 | 4 | Parschauer Karah Herdman | RARE | Common Stock | D | 48.4300 | 10,000 | 484 | 34,293 | ||||
| 2020-09-24 | 2020-09-23 | 4 | Parschauer Karah Herdman | RARE | Stock Option (Right to Buy) | D | 48.43 | -10,000 | 27,000 | |||||
| 2020-09-24 | 2020-09-23 | 4 | Parschauer Karah Herdman | RARE | Common Stock | D | 85.0000 | -10,000 | -850 | 24,293 | ||||
| 2020-09-24 | 2020-09-23 | 4 | Parschauer Karah Herdman | RARE | Common Stock | D | 48.4300 | 10,000 | 484 | 34,293 | ||||
| 2020-09-02 | 2020-09-01 | 4 | KAKKIS EMIL D By Emil Kakkis and Jenny Soriano Living Trust, dated June 18, 2009 | RARE | Common Stock | I | 82.6300 | -30,000 | -2,479 | 2,389,741 | ||||
| 2020-08-25 | 2020-08-21 | 4 | Aliski William | RARE | Stock Option (Right to Buy) | D | 58.74 | -5,000 | 0 | |||||
| 2020-08-25 | 2020-08-21 | 4 | Aliski William | RARE | Common Stock | D | 86.5700 | -5,000 | -433 | 57,018 | ||||
| 2020-08-25 | 2020-08-21 | 4 | Aliski William | RARE | Common Stock | D | 58.7400 | 5,000 | 294 | 62,018 | ||||
| 2020-08-19 | 2020-08-17 | 4 | Parschauer Karah Herdman | RARE | Stock Option (Right to Buy) | D | 54.50 | -10,000 | 45,000 | |||||
| 2020-08-19 | 2020-08-17 | 4 | Parschauer Karah Herdman | RARE | Common Stock | D | 88.3900 | -2,370 | -209 | 24,293 | ||||
| 2020-08-19 | 2020-08-17 | 4 | Parschauer Karah Herdman | RARE | Common Stock | D | 88.4400 | -10,000 | -884 | 26,663 | ||||
| 2020-08-19 | 2020-08-17 | 4 | Parschauer Karah Herdman | RARE | Common Stock | D | 54.5000 | 10,000 | 545 | 36,663 | ||||
| 2020-08-19 | 2020-08-17 | 4 | Sharp Shalini | RARE | Stock Option (Right to Buy) | D | 48.43 | -3,669 | 15,312 | |||||
| 2020-08-19 | 2020-08-17 | 4 | Sharp Shalini | RARE | Stock Option (Right to Buy) | D | 67.55 | -7,188 | 15,812 | |||||
| 2020-08-19 | 2020-08-17 | 4 | Sharp Shalini | RARE | Stock Option (Right to Buy) | D | 70.57 | -500 | 0 | |||||
| 2020-08-19 | 2020-08-17 | 4 | Sharp Shalini | RARE | Common Stock | D | 88.3800 | -3,669 | -324 | 98,187 | ||||
| 2020-08-19 | 2020-08-17 | 4 | Sharp Shalini | RARE | Common Stock | D | 48.4300 | 3,669 | 178 | 101,856 | ||||
| 2020-08-19 | 2020-08-17 | 4 | Sharp Shalini | RARE | Common Stock | D | 88.3800 | -7,188 | -635 | 98,187 | ||||
| 2020-08-19 | 2020-08-17 | 4 | Sharp Shalini | RARE | Common Stock | D | 67.5500 | 7,188 | 486 | 105,375 | ||||
| 2020-08-19 | 2020-08-17 | 4 | Sharp Shalini | RARE | Common Stock | D | 88.3800 | -500 | -44 | 98,187 | ||||
| 2020-08-19 | 2020-08-17 | 4 | Sharp Shalini | RARE | Common Stock | D | 70.5700 | 500 | 35 | 98,687 | ||||
| 2020-08-19 | 2020-08-17 | 4 | Sharp Shalini | RARE | Common Stock | D | 88.5400 | -2,560 | -227 | 98,187 | ||||
| 2020-08-19 | 2020-08-17 | 4 | Sharp Shalini | RARE | Common Stock | D | 88.2400 | -461 | -41 | 100,747 | ||||
| 2020-08-11 | 2020-08-10 | 4 | SIEGALL CLAY B | RARE | Stock Option (Right to Buy) | D | 40.37 | -1,596 | 0 | |||||
| 2020-08-11 | 2020-08-10 | 4 | SIEGALL CLAY B | RARE | Common Stock | D | 85.0100 | -1,596 | -136 | 2,550 | ||||
| 2020-08-11 | 2020-08-10 | 4 | SIEGALL CLAY B | RARE | Common Stock | D | 40.3700 | 1,596 | 64 | 4,146 | ||||
| 2020-08-11 | 2020-08-10 | 4 | SIEGALL CLAY B | RARE | Common Stock | D | 85.0100 | -9,750 | -829 | 2,550 | ||||
| 2020-08-11 | 2020-08-07 | 4 | SIEGALL CLAY B | RARE | Stock Option (Right to Buy) | D | 21.00 | -17,500 | 0 | |||||
| 2020-08-11 | 2020-08-07 | 4 | SIEGALL CLAY B | RARE | Stock Option (Right to Buy) | D | 40.37 | -5,904 | 1,596 | |||||
| 2020-08-11 | 2020-08-07 | 4 | SIEGALL CLAY B | RARE | Common Stock | D | 85.5500 | -23,404 | -2,002 | 12,300 | ||||
| 2020-08-11 | 2020-08-07 | 4 | SIEGALL CLAY B | RARE | Common Stock | D | 21.0000 | 17,500 | 368 | 35,704 | ||||
| 2020-08-11 | 2020-08-07 | 4 | SIEGALL CLAY B | RARE | Common Stock | D | 40.3700 | 5,904 | 238 | 18,204 | ||||
| 2020-07-15 | 2020-07-13 | 4 | KAKKIS EMIL D By Emil Kakkis and Jenny Soriano Living Trust, dated June 18, 2009 | RARE | Common Stock | I | 85.3500 | -40,000 | -3,414 | 2,419,741 | ||||
| 2020-07-10 | 2020-07-08 | 4 | Huizenga Theodore Alan | RARE | Stock Option (Right to Buy) | D | 21.00 | -2,000 | 12,000 | |||||
| 2020-07-10 | 2020-07-08 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 91.0000 | -2,000 | -182 | 16,582 | ||||
| 2020-07-10 | 2020-07-08 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 21.0000 | 2,000 | 42 | 18,582 | ||||
| 2020-07-10 | 2020-07-08 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 91.0000 | -638 | -58 | 16,582 | ||||
| 2020-07-08 | 2020-07-06 | 4 | Harris Erik | RARE | Common Stock | D | 86.7500 | -260 | -23 | 23,590 | ||||
| 2020-07-08 | 2020-07-06 | 4 | Fust Matthew K | RARE | Stock Option (Right to Buy) | D | 21.00 | -6,181 | 0 | |||||
| 2020-07-08 | 2020-07-06 | 4 | Fust Matthew K | RARE | Common Stock | D | 90.0000 | -6,181 | -556 | 13,550 | ||||
| 2020-07-08 | 2020-07-06 | 4 | Fust Matthew K | RARE | Common Stock | D | 21.0000 | 6,181 | 130 | 19,731 | ||||
| 2020-07-06 | 2020-07-01 | 4 | Fust Matthew K | RARE | Stock Option (Right to Buy) | D | 21.00 | -5,000 | 6,181 | |||||
| 2020-07-06 | 2020-07-01 | 4 | Fust Matthew K | RARE | Common Stock | D | 85.0000 | -5,000 | -425 | 13,550 | ||||
| 2020-07-06 | 2020-07-01 | 4 | Fust Matthew K | RARE | Common Stock | D | 21.0000 | 5,000 | 105 | 18,550 | ||||
| 2020-07-06 | 2020-07-01 | 4 | Huizenga Theodore Alan | RARE | Stock Option (Right to Buy) | D | 21.00 | -1,500 | 14,000 | |||||
| 2020-07-06 | 2020-07-01 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 81.0000 | -1,500 | -122 | 17,220 | ||||
| 2020-07-06 | 2020-07-01 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 21.0000 | 1,500 | 32 | 18,720 | ||||
| 2020-07-06 | 2020-07-01 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 81.0000 | -1,111 | -90 | 17,220 | ||||
| 2020-06-30 | 2020-06-26 | 4 | SULIMAN SHEHNAAZ | RARE | Stock Option (Right to Buy) | D | 76.58 | 4,250 | 4,250 | |||||
| 2020-06-30 | 2020-06-26 | 4 | SULIMAN SHEHNAAZ | RARE | Common Stock | D | 2,550 | 5,550 | ||||||
| 2020-06-30 | 2020-06-26 | 4 | WELCH DANIEL G | RARE | Stock Option (Right to Buy) | D | 76.58 | 4,250 | 4,250 | |||||
| 2020-06-30 | 2020-06-26 | 4 | WELCH DANIEL G | RARE | Common Stock | D | 2,550 | 12,300 | ||||||
| 2020-06-30 | 2020-06-26 | 4 | Aliski William | RARE | Stock Option (Right to Buy) | D | 76.58 | 4,250 | 4,250 | |||||
| 2020-06-30 | 2020-06-26 | 4 | Aliski William | RARE | Common Stock | D | 2,550 | 57,018 | ||||||
| 2020-06-30 | 2020-06-26 | 4 | Dunsire Deborah | RARE | Stock Option (Right to Buy) | D | 76.58 | 4,250 | 4,250 | |||||
| 2020-06-30 | 2020-06-26 | 4 | Dunsire Deborah | RARE | Common Stock | D | 2,550 | 10,425 | ||||||
| 2020-06-30 | 2020-06-26 | 4 | Ekman Lars | RARE | Stock Option (Right to Buy) | D | 76.58 | 4,250 | 4,250 | |||||
| 2020-06-30 | 2020-06-26 | 4 | Ekman Lars | RARE | Common Stock | D | 2,550 | 12,300 | ||||||
| 2020-06-30 | 2020-06-26 | 4 | Fust Matthew K | RARE | Stock Option (Right to Buy) | D | 76.58 | 4,250 | 4,250 | |||||
| 2020-06-30 | 2020-06-26 | 4 | Fust Matthew K | RARE | Common Stock | D | 2,550 | 13,550 | ||||||
| 2020-06-30 | 2020-06-26 | 4 | NARACHI MICHAEL | RARE | Stock Option (Right to Buy) | D | 76.58 | 4,250 | 4,250 | |||||
| 2020-06-30 | 2020-06-26 | 4 | NARACHI MICHAEL | RARE | Common Stock | D | 2,550 | 12,300 | ||||||
| 2020-06-30 | 2020-06-26 | 4 | SIEGALL CLAY B | RARE | Stock Option (Right to Buy) | D | 76.58 | 4,250 | 4,250 | |||||
| 2020-06-30 | 2020-06-26 | 4 | SIEGALL CLAY B | RARE | Common Stock | D | 2,550 | 12,300 | ||||||
| 2020-06-22 | 2020-06-20 | 4 | Parschauer Karah Herdman | RARE | Common Stock | D | 78.2200 | -649 | -51 | 26,663 | ||||
| 2020-06-22 | 2020-06-19 | 4 | Harris Erik | RARE | Common Stock | D | 78.2200 | -303 | -24 | 23,850 | ||||
| 2020-06-05 | 2020-06-04 | 4 | Sharp Shalini | RARE | Stock Option (Right to Buy) | D | 48.43 | -2,564 | 18,981 | |||||
| 2020-06-05 | 2020-06-04 | 4 | Sharp Shalini | RARE | Common Stock | D | 74.0100 | -2,564 | -190 | 101,208 | ||||
| 2020-06-05 | 2020-06-04 | 4 | Sharp Shalini | RARE | Common Stock | D | 48.4300 | 2,564 | 124 | 103,772 | ||||
| 2020-06-05 | 2020-06-03 | 4 | Sharp Shalini | RARE | Stock Option (Right to Buy) | D | 48.43 | -10,234 | 21,545 | |||||
| 2020-06-05 | 2020-06-03 | 4 | Sharp Shalini | RARE | Common Stock | D | 74.2300 | -10,234 | -760 | 101,208 | ||||
| 2020-06-05 | 2020-06-03 | 4 | Sharp Shalini | RARE | Common Stock | D | 48.4300 | 10,234 | 496 | 111,442 | ||||
| 2020-06-03 | 2020-05-18 | 4 | Aliski William By trust | RARE | Common Stock | I | 74.0161 | -20,000 | -1,480 | 70,350 | ||||
| 2020-06-03 | 2020-06-01 | 4 | Kassberg Thomas Richard | RARE | Common Stock | D | 69.3800 | -348 | -24 | 101,740 | ||||
| 2020-06-03 | 2020-06-01 | 4 | Sharp Shalini | RARE | Common Stock | D | 69.3800 | -348 | -24 | 101,208 | ||||
| 2020-06-03 | 2020-06-01 | 4 | Pinion John Richard | RARE | Common Stock | D | 69.3800 | -262 | -18 | 49,341 | ||||
| 2020-06-03 | 2020-06-01 | 4 | Huang Dennis Karl | RARE | Common Stock | D | 69.3800 | -262 | -18 | 34,961 | ||||
| 2020-06-03 | 2020-06-01 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 69.3800 | -1,334 | -93 | 611,041 | ||||
| 2020-05-27 | 2020-05-26 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 74.9300 | -260 | -19 | 18,331 | ||||
| 2020-05-27 | 2020-05-25 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 73.8100 | -433 | -32 | 18,591 | ||||
| 2020-05-20 | 2020-05-19 | 4 | Sharp Shalini | RARE | Stock Option (Right to Buy) | D | 70.57 | -3,907 | 500 | |||||
| 2020-05-20 | 2020-05-19 | 4 | Sharp Shalini | RARE | Stock Option (Right to Buy) | D | 48.43 | -3,221 | 31,779 | |||||
| 2020-05-20 | 2020-05-19 | 4 | Sharp Shalini | RARE | Common Stock | D | 73.3200 | -3,907 | -286 | 101,556 | ||||
| 2020-05-20 | 2020-05-19 | 4 | Sharp Shalini | RARE | Common Stock | D | 70.5700 | 3,907 | 276 | 104,851 | ||||
| 2020-05-20 | 2020-05-19 | 4 | Sharp Shalini | RARE | Common Stock | D | 73.3200 | -3,221 | -236 | 100,944 | ||||
| 2020-05-20 | 2020-05-19 | 4 | Sharp Shalini | RARE | Common Stock | D | 48.4300 | 3,221 | 156 | 104,165 | ||||
| 2020-05-20 | 2020-05-18 | 4 | Sharp Shalini | RARE | Stock Option (Right to Buy) | D | 70.57 | -19,593 | 4,407 | |||||
| 2020-05-20 | 2020-05-18 | 4 | Sharp Shalini | RARE | Common Stock | D | 73.2900 | -2,392 | -175 | 100,944 | ||||
| 2020-05-20 | 2020-05-18 | 4 | Sharp Shalini | RARE | Common Stock | D | 73.3400 | -19,593 | -1,437 | 103,336 | ||||
| 2020-05-20 | 2020-05-18 | 4 | Sharp Shalini | RARE | Common Stock | D | 70.5700 | 19,593 | 1,383 | 122,929 | ||||
| 2020-05-20 | 2020-05-18 | 4 | Aliski William | RARE | Stock Option (Right to Buy) | D | 40.37 | -7,500 | 0 | |||||
| 2020-05-20 | 2020-05-18 | 4 | Aliski William | RARE | Common Stock | D | 74.6500 | -7,500 | -560 | 47,924 | ||||
| 2020-05-20 | 2020-05-18 | 4 | Aliski William | RARE | Common Stock | D | 40.3700 | 7,500 | 303 | 55,424 | ||||
| 2020-05-19 | 2020-05-18 | 4 | Parschauer Karah Herdman | RARE | Common Stock | D | 74.7150 | -2,722 | -203 | 27,312 | ||||
| 2020-05-19 | 2020-05-18 | 4 | Fust Matthew K | RARE | Common Stock | D | 75.0000 | -1,875 | -141 | 11,000 | ||||
| 2020-05-19 | 2020-05-15 | 4 | Huizenga Theodore Alan | RARE | Stock Option (Right to Buy) | D | 21.00 | -1,500 | 15,500 | |||||
| 2020-05-19 | 2020-05-15 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 71.0000 | -1,500 | -106 | 19,024 | ||||
| 2020-05-19 | 2020-05-15 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 21.0000 | 1,500 | 32 | 20,219 | ||||
| 2020-05-19 | 2020-05-15 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 71.0000 | -961 | -68 | 18,719 | ||||
| 2020-05-08 | 2020-05-06 | 4 | Harris Erik | RARE | Common Stock | D | 66.2600 | -209 | -14 | 24,153 | ||||
| 2020-05-08 | 2020-05-06 | 4 | Bedrosian Camille L | RARE | Common Stock | D | 66.2600 | -249 | -16 | 36,051 | ||||
| 2020-05-08 | 2020-05-06 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 66.2600 | -852 | -56 | 652,797 | ||||
| 2020-05-08 | 2020-05-06 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 66.2600 | -138 | -9 | 19,680 | ||||
| 2020-05-08 | 2020-05-06 | 4 | Huang Dennis Karl | RARE | Common Stock | D | 66.2600 | -248 | -16 | 34,979 | ||||
| 2020-05-08 | 2020-05-06 | 4 | Parschauer Karah Herdman | RARE | Common Stock | D | 66.2600 | -248 | -16 | 29,904 | ||||
| 2020-05-08 | 2020-05-06 | 4 | Kassberg Thomas Richard | RARE | Common Stock | D | 66.2600 | -248 | -16 | 101,675 | ||||
| 2020-05-08 | 2020-05-06 | 4 | Pinion John Richard | RARE | Common Stock | D | 66.2600 | -248 | -16 | 48,991 | ||||
| 2020-05-08 | 2020-05-06 | 4 | Sharp Shalini | RARE | Common Stock | D | 66.2600 | -248 | -16 | 103,336 | ||||
| 2020-04-24 | 2020-04-22 | 4 | Fust Matthew K | RARE | Common Stock | D | 65.0000 | -1,875 | -122 | 12,875 | ||||
| 2020-04-21 | 2020-04-19 | 4 | Pinion John Richard | RARE | Common Stock | D | 58.5700 | -248 | -15 | 49,239 | ||||
| 2020-04-21 | 2020-04-19 | 4 | Sharp Shalini | RARE | Common Stock | D | 58.5700 | -248 | -15 | 103,584 | ||||
| 2020-04-21 | 2020-04-19 | 4 | Harris Erik | RARE | Common Stock | D | 58.5700 | -210 | -12 | 24,362 | ||||
| 2020-04-21 | 2020-04-19 | 4 | Huang Dennis Karl | RARE | Common Stock | D | 58.5700 | -248 | -15 | 35,227 | ||||
| 2020-04-21 | 2020-04-19 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 58.5700 | -140 | -8 | 19,818 | ||||
| 2020-04-21 | 2020-04-19 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 58.5700 | -851 | -50 | 653,649 | ||||
| 2020-04-21 | 2020-04-19 | 4 | Kassberg Thomas Richard | RARE | Common Stock | D | 58.5700 | -248 | -15 | 101,923 | ||||
| 2020-04-21 | 2020-04-19 | 4 | Parschauer Karah Herdman | RARE | Common Stock | D | 58.5700 | -248 | -15 | 30,152 | ||||
| 2020-03-13 | 2020-03-12 | 4 | KAKKIS EMIL D | RARE | Warrant (Right to Buy) | D | 3.01 | -66,533 | 0 | |||||
| 2020-03-13 | 2020-03-12 | 4 | KAKKIS EMIL D | RARE | Warrant (Right to Buy) | D | 3.01 | -83,167 | 0 | |||||
| 2020-03-13 | 2020-03-12 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 3.0060 | 66,533 | 200 | 654,500 | ||||
| 2020-03-13 | 2020-03-12 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 3.0060 | 83,167 | 250 | 587,967 | ||||
| 2020-03-04 | 2020-03-01 | 4/A | Huizenga Theodore Alan | RARE | Stock Option (Right to Buy) | D | 56.08 | 13,280 | 13,280 | |||||
| 2020-03-04 | 2020-03-01 | 4/A | Huizenga Theodore Alan | RARE | Common Stock | D | 4,400 | 19,958 | ||||||
| 2020-03-03 | 2020-03-01 | 4 | Harris Erik | RARE | Stock Option (Right to Buy) | D | 56.08 | 22,000 | 22,000 | |||||
| 2020-03-03 | 2020-03-01 | 4 | Harris Erik | RARE | Common Stock | D | 56.0800 | -824 | -46 | 24,572 | ||||
| 2020-03-03 | 2020-03-01 | 4 | Harris Erik | RARE | Common Stock | D | 3,287 | 25,396 | ||||||
| 2020-03-03 | 2020-03-01 | 4 | Harris Erik | RARE | Common Stock | D | 7,800 | 22,109 | ||||||
| 2020-03-03 | 2020-03-01 | 4 | Huizenga Theodore Alan | RARE | Stock Option (Right to Buy) | D | 56.08 | 7,480 | 7,480 | |||||
| 2020-03-03 | 2020-03-01 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 56.0800 | -388 | -22 | 17,058 | ||||
| 2020-03-03 | 2020-03-01 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 1,500 | 17,446 | ||||||
| 2020-03-03 | 2020-03-01 | 4 | KAKKIS EMIL D | RARE | Stock Option (Right to Buy) | D | 56.08 | 56,100 | 56,100 | |||||
| 2020-03-03 | 2020-03-01 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 56.0800 | -6,896 | -387 | 504,800 | ||||
| 2020-03-03 | 2020-03-01 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 18,782 | 511,696 | ||||||
| 2020-03-03 | 2020-03-01 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 17,000 | 492,914 | ||||||
| 2020-03-03 | 2020-03-01 | 4 | Parschauer Karah Herdman | RARE | Stock Option (Right to Buy) | D | 56.08 | 22,000 | 22,000 | |||||
| 2020-03-03 | 2020-03-01 | 4 | Parschauer Karah Herdman | RARE | Common Stock | D | 56.0800 | -2,118 | -119 | 30,400 | ||||
| 2020-03-03 | 2020-03-01 | 4 | Parschauer Karah Herdman | RARE | Common Stock | D | 5,634 | 32,518 | ||||||
| 2020-03-03 | 2020-03-01 | 4 | Parschauer Karah Herdman | RARE | Common Stock | D | 7,800 | 26,884 | ||||||
| 2020-03-03 | 2020-03-01 | 4 | Pinion John Richard | RARE | Stock Option (Right to Buy) | D | 56.08 | 22,000 | 22,000 | |||||
| 2020-03-03 | 2020-03-01 | 4 | Pinion John Richard | RARE | Common Stock | D | 56.0800 | 3,085 | 173 | 49,487 | ||||
| 2020-03-03 | 2020-03-01 | 4 | Pinion John Richard | RARE | Common Stock | D | 5,634 | 52,572 | ||||||
| 2020-03-03 | 2020-03-01 | 4 | Pinion John Richard | RARE | Common Stock | D | 7,800 | 46,938 | ||||||
| 2020-03-03 | 2020-03-01 | 4 | Huang Dennis Karl | RARE | Stock Option (Right to Buy) | D | 56.08 | 22,000 | 22,000 | |||||
| 2020-03-03 | 2020-03-01 | 4 | Huang Dennis Karl | RARE | Common Stock | D | 56.0800 | -1,779 | -100 | 35,475 | ||||
| 2020-03-03 | 2020-03-01 | 4 | Huang Dennis Karl | RARE | Common Stock | D | 5,634 | 37,013 | ||||||
| 2020-03-03 | 2020-03-01 | 4 | Huang Dennis Karl | RARE | Common Stock | D | 7,800 | 31,379 | ||||||
| 2020-03-03 | 2020-03-01 | 4 | Sharp Shalini | RARE | Common Stock | D | 56.0800 | -2,325 | -130 | 103,832 | ||||
| 2020-03-03 | 2020-03-01 | 4 | Sharp Shalini | RARE | Common Stock | D | 5,634 | 106,157 | ||||||
| 2020-03-03 | 2020-03-01 | 4 | Kassberg Thomas Richard | RARE | Stock Option (Right to Buy) | D | 56.08 | 20,000 | 20,000 | |||||
| 2020-03-03 | 2020-03-01 | 4 | Kassberg Thomas Richard | RARE | Common Stock | D | 56.0800 | -2,067 | -116 | 102,171 | ||||
| 2020-03-03 | 2020-03-01 | 4 | Kassberg Thomas Richard | RARE | Common Stock | D | 5,634 | 104,109 | ||||||
| 2020-03-03 | 2020-03-01 | 4 | Kassberg Thomas Richard | RARE | Common Stock | D | 6,800 | 98,475 | ||||||
| 2020-03-03 | 2020-03-01 | 4 | Bedrosian Camille L | RARE | Stock Option (Right to Buy) | D | 56.08 | 21,000 | 21,000 | |||||
| 2020-03-03 | 2020-03-01 | 4 | Bedrosian Camille L | RARE | Common Stock | D | 56.0800 | -1,249 | -70 | 36,300 | ||||
| 2020-03-03 | 2020-03-01 | 4 | Bedrosian Camille L | RARE | Common Stock | D | 5,634 | 37,549 | ||||||
| 2020-03-03 | 2020-03-01 | 4 | Bedrosian Camille L | RARE | Common Stock | D | 7,300 | 31,915 | ||||||
| 2020-01-31 | 2020-01-30 | 4 | Bedrosian Camille L | RARE | Common Stock | D | 53.2300 | -1,624 | -86 | 24,615 | ||||
| 2020-01-15 | 2020-01-14 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 61.0000 | -1,000 | -61 | 15,946 | ||||
| 2019-10-16 | 2019-10-14 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 800 | 16,785 | ||||||
| 2019-10-16 | 2019-10-14 | 4 | Bedrosian Camille L | RARE | Common Stock | D | 1,437 | 26,239 | ||||||
| 2019-10-16 | 2019-10-14 | 4 | Sharp Shalini | RARE | Common Stock | D | 1,434 | 100,523 | ||||||
| 2019-10-16 | 2019-10-14 | 4 | Pinion John Richard | RARE | Common Stock | D | 1,434 | 39,138 | ||||||
| 2019-10-16 | 2019-10-14 | 4 | Parschauer Karah Herdman | RARE | Common Stock | D | 1,434 | 19,084 | ||||||
| 2019-10-16 | 2019-10-14 | 4 | Kassberg Thomas Richard | RARE | Common Stock | D | 1,434 | 91,675 | ||||||
| 2019-10-16 | 2019-10-14 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 3,435 | 475,914 | ||||||
| 2019-10-16 | 2019-10-14 | 4 | Huang Dennis Karl | RARE | Common Stock | D | 1,434 | 23,579 | ||||||
| 2019-10-16 | 2019-10-14 | 4 | Harris Erik | RARE | Common Stock | D | 1,208 | 14,309 | ||||||
| 2019-10-07 | 2019-10-04 | 4 | Hogenhuis Wladimir | RARE | Common Stock | D | 44.5200 | -1,297 | -58 | 18,703 | ||||
| 2019-09-17 | 2019-09-16 | 4 | Sharp Shalini | RARE | Stock Option (Right to Buy) | D | 6.86 | -24,880 | 2,998 | |||||
| 2019-09-17 | 2019-09-16 | 4 | Sharp Shalini | RARE | Stock Option (Right to Buy) | D | 0.81 | -6,963 | 0 | |||||
| 2019-09-17 | 2019-09-16 | 4 | Sharp Shalini | RARE | Common Stock | D | 6.8600 | 24,880 | 171 | 99,089 | ||||
| 2019-09-17 | 2019-09-16 | 4 | Sharp Shalini | RARE | Common Stock | D | 0.8100 | 6,963 | 6 | 74,209 | ||||
| 2019-09-11 | 2019-09-11 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 43.6300 | 5,000 | 218 | 472,479 | ||||
| 2019-07-17 | 2019-07-16 | 4 | Pinion John Richard | RARE | Common Stock | D | 59.1700 | -649 | -38 | 37,704 | ||||
| 2019-07-09 | 2019-07-06 | 4 | Harris Erik | RARE | Common Stock | D | 59.5100 | -260 | -15 | 13,101 | ||||
| 2019-06-24 | 2019-06-24 | 4 | Parschauer Karah Herdman | RARE | Common Stock | D | 61.5000 | -1,226 | -75 | 17,650 | ||||
| 2019-06-24 | 2019-06-21 | 4 | Parschauer Karah Herdman | RARE | Common Stock | D | 63.0100 | -1,489 | -94 | 18,876 | ||||
| 2019-06-24 | 2019-06-20 | 4 | Parschauer Karah Herdman | RARE | Common Stock | D | 63.4800 | -649 | -41 | 20,365 | ||||
| 2019-06-21 | 3 | Harris Erik | RARE | Common Stock | D | 19,722 | ||||||||
| 2019-06-21 | 3 | Harris Erik | RARE | Common Stock | D | 19,722 | ||||||||
| 2019-06-21 | 3 | Harris Erik | RARE | Common Stock | D | 19,722 | ||||||||
| 2019-06-21 | 2019-06-19 | 4 | Harris Erik | RARE | Stock Option (Right to Buy) | D | 63.27 | 12,000 | 12,000 | |||||
| 2019-06-21 | 2019-06-19 | 4 | Harris Erik | RARE | Common Stock | D | 3,500 | 13,361 | ||||||
| 2019-06-13 | 2019-06-11 | 4 | Aliski William | RARE | Stock Option (Right to Buy) | D | 58.74 | 5,000 | 5,000 | |||||
| 2019-06-13 | 2019-06-11 | 4 | Aliski William | RARE | Common Stock | D | 3,000 | 47,924 | ||||||
| 2019-06-13 | 2019-06-11 | 4 | Fust Matthew K | RARE | Stock Option (Right to Buy) | D | 58.74 | 5,000 | 5,000 | |||||
| 2019-06-13 | 2019-06-11 | 4 | Fust Matthew K | RARE | Common Stock | D | 3,000 | 14,750 | ||||||
| 2019-06-13 | 2019-06-11 | 4 | NARACHI MICHAEL | RARE | Stock Option (Right to Buy) | D | 58.74 | 5,000 | 5,000 | |||||
| 2019-06-13 | 2019-06-11 | 4 | NARACHI MICHAEL | RARE | Common Stock | D | 3,000 | 9,750 | ||||||
| 2019-06-13 | 2019-06-11 | 4 | SIEGALL CLAY B | RARE | Stock Option (Right to Buy) | D | 58.74 | 5,000 | 5,000 | |||||
| 2019-06-13 | 2019-06-11 | 4 | SIEGALL CLAY B | RARE | Common Stock | D | 3,000 | 9,750 | ||||||
| 2019-06-13 | 2019-06-11 | 4 | WELCH DANIEL G | RARE | Stock Option (Right to Buy) | D | 58.74 | 5,000 | 5,000 | |||||
| 2019-06-13 | 2019-06-11 | 4 | WELCH DANIEL G | RARE | Common Stock | D | 3,000 | 9,750 | ||||||
| 2019-06-13 | 2019-06-11 | 4 | SULIMAN SHEHNAAZ | RARE | Stock Option (Right to Buy) | D | 58.74 | 5,000 | 5,000 | |||||
| 2019-06-13 | 2019-06-11 | 4 | SULIMAN SHEHNAAZ | RARE | Common Stock | D | 3,000 | 3,000 | ||||||
| 2019-06-13 | 2019-06-11 | 4 | Dunsire Deborah | RARE | Stock Option (Right to Buy) | D | 58.74 | 5,000 | 5,000 | |||||
| 2019-06-13 | 2019-06-11 | 4 | Dunsire Deborah | RARE | Common Stock | D | 3,000 | 7,875 | ||||||
| 2019-06-13 | 2019-06-11 | 4 | Ekman Lars | RARE | Stock Option (Right to Buy) | D | 58.74 | 5,000 | 5,000 | |||||
| 2019-06-13 | 2019-06-11 | 4 | Ekman Lars | RARE | Common Stock | D | 3,000 | 9,750 | ||||||
| 2019-06-04 | 2019-06-01 | 4 | Sharp Shalini | RARE | Common Stock | D | 54.9300 | -346 | -19 | 67,246 | ||||
| 2019-06-04 | 2019-06-01 | 4 | Huang Dennis Karl | RARE | Common Stock | D | 54.9300 | -260 | -14 | 22,145 | ||||
| 2019-06-04 | 2019-06-01 | 4 | Pinion John Richard | RARE | Common Stock | D | 54.9300 | -260 | -14 | 38,353 | ||||
| 2019-06-04 | 2019-06-01 | 4 | Kassberg Thomas Richard | RARE | Common Stock | D | 54.9300 | -346 | -19 | 90,241 | ||||
| 2019-06-04 | 2019-06-01 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 54.9300 | -1,327 | -73 | 467,479 | ||||
| 2019-05-29 | 2019-05-25 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 57.1800 | -433 | -25 | 15,985 | ||||
| 2019-05-22 | 2019-05-21 | 4 | Sharp Shalini | RARE | Common Stock | D | 59.5000 | -381 | -23 | 67,592 | ||||
| 2019-05-22 | 2019-05-21 | 4 | Kassberg Thomas Richard | RARE | Common Stock | D | 59.5000 | -381 | -23 | 90,587 | ||||
| 2019-05-22 | 2019-05-21 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 59.5000 | -1,414 | -84 | 468,806 | ||||
| 2019-05-22 | 2019-05-21 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 59.5000 | -156 | -9 | 16,418 | ||||
| 2019-05-07 | 2019-05-06 | 4 | Huang Dennis Karl | RARE | Common Stock | D | 1,434 | 22,405 | ||||||
| 2019-05-07 | 2019-05-05 | 4 | Huang Dennis Karl | RARE | Common Stock | D | 67.9900 | -649 | -44 | 20,971 | ||||
| 2019-05-07 | 2019-05-06 | 4 | Kassberg Thomas Richard | RARE | Common Stock | D | 1,434 | 90,968 | ||||||
| 2019-05-07 | 2019-05-06 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 800 | 16,574 | ||||||
| 2019-05-07 | 2019-05-06 | 4 | Bedrosian Camille L | RARE | Common Stock | D | 1,438 | 24,802 | ||||||
| 2019-05-07 | 2019-05-06 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 3,435 | 470,220 | ||||||
| 2019-05-07 | 2019-05-06 | 4 | Parschauer Karah Herdman | RARE | Common Stock | D | 1,434 | 21,014 | ||||||
| 2019-05-07 | 2019-05-06 | 4 | Pinion John Richard | RARE | Common Stock | D | 1,434 | 38,613 | ||||||
| 2019-05-07 | 2019-05-06 | 4 | Sharp Shalini | RARE | Common Stock | D | 1,434 | 67,973 | ||||||
| 2019-04-30 | 2019-04-29 | 4 | Parschauer Karah Herdman | RARE | Common Stock | D | 68.3000 | -468 | -32 | 19,580 | ||||
| 2019-04-23 | 2019-04-19 | 4 | Kassberg Thomas Richard | RARE | Common Stock | D | 64.4300 | -248 | -16 | 89,226 | ||||
| 2019-04-23 | 2019-04-19 | 4 | Sharp Shalini | RARE | Common Stock | D | 64.4300 | -248 | -16 | 66,078 | ||||
| 2019-04-23 | 2019-04-19 | 4 | Parschauer Karah Herdman | RARE | Common Stock | D | 64.4300 | -248 | -16 | 20,048 | ||||
| 2019-04-23 | 2019-04-19 | 4 | Pinion John Richard | RARE | Common Stock | D | 64.4300 | -248 | -16 | 36,718 | ||||
| 2019-04-23 | 2019-04-19 | 4 | Huang Dennis Karl | RARE | Common Stock | D | 64.4300 | -248 | -16 | 21,445 | ||||
| 2019-04-23 | 2019-04-19 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 64.4300 | -138 | -9 | 15,504 | ||||
| 2019-04-23 | 2019-04-19 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 64.4300 | -798 | -51 | 466,785 | ||||
| 2019-04-17 | 2019-03-05 | 4/A | KAKKIS EMIL D | RARE | Common Stock | D | 65.5200 | -2,890 | -189 | 467,583 | ||||
| 2019-04-17 | 2019-03-01 | 4/A | KAKKIS EMIL D | RARE | Stock Option (Right to Buy) | D | 67.55 | 66,000 | 66,000 | |||||
| 2019-04-17 | 2019-03-01 | 4/A | KAKKIS EMIL D | RARE | Common Stock | D | 20,000 | 470,473 | ||||||
| 2019-04-17 | 2019-03-05 | 4/A | Sharp Shalini | RARE | Common Stock | D | 65.5200 | -1,012 | -66 | 69,125 | ||||
| 2019-04-17 | 2019-03-01 | 4/A | Sharp Shalini | RARE | Stock Option (Right to Buy) | D | 67.55 | 23,000 | 23,000 | |||||
| 2019-04-17 | 2019-03-01 | 4/A | Sharp Shalini | RARE | Common Stock | D | 8,000 | 70,137 | ||||||
| 2019-04-17 | 2019-03-18 | 4/A | Sharp Shalini | RARE | Stock Option (Right to Buy) | D | 6.86 | -12,000 | 27,878 | |||||
| 2019-04-17 | 2019-03-18 | 4/A | Sharp Shalini | RARE | Common Stock | D | 70.0000 | -14,800 | -1,036 | 66,326 | ||||
| 2019-04-17 | 2019-03-18 | 4/A | Sharp Shalini | RARE | Common Stock | D | 6.8600 | 12,000 | 82 | 81,126 | ||||
| 2019-04-17 | 2019-03-05 | 4/A | Parschauer Karah Herdman | RARE | Common Stock | D | 65.5200 | -886 | -58 | 20,296 | ||||
| 2019-04-17 | 2019-03-01 | 4/A | Parschauer Karah Herdman | RARE | Stock Option (Right to Buy) | D | 67.55 | 21,500 | 21,500 | |||||
| 2019-04-17 | 2019-03-01 | 4/A | Parschauer Karah Herdman | RARE | Common Stock | D | 7,000 | 21,182 | ||||||
| 2019-04-17 | 2019-03-05 | 4/A | Pinion John Richard | RARE | Common Stock | D | 65.5200 | -722 | -47 | 36,966 | ||||
| 2019-04-17 | 2019-03-01 | 4/A | Pinion John Richard | RARE | Stock Option (Right to Buy) | D | 67.55 | 23,000 | 23,000 | |||||
| 2019-04-17 | 2019-03-01 | 4/A | Pinion John Richard | RARE | Common Stock | D | 20,000 | 37,688 | ||||||
| 2019-04-17 | 2019-03-05 | 4/A | Huang Dennis Karl | RARE | Common Stock | D | 65.5200 | -626 | -41 | 21,693 | ||||
| 2019-04-17 | 2019-03-01 | 4/A | Huang Dennis Karl | RARE | Stock Option (Right to Buy) | D | 67.55 | 20,000 | 20,000 | |||||
| 2019-04-17 | 2019-03-01 | 4/A | Huang Dennis Karl | RARE | Common Stock | D | 6,000 | 22,319 | ||||||
| 2019-04-17 | 2019-03-05 | 4/A | Huizenga Theodore Alan | RARE | Common Stock | D | 65.5200 | -254 | -17 | 15,642 | ||||
| 2019-04-17 | 2019-03-01 | 4/A | Huizenga Theodore Alan | RARE | Stock Option (Right to Buy) | D | 67.55 | 6,840 | 6,840 | |||||
| 2019-04-17 | 2019-03-01 | 4/A | Huizenga Theodore Alan | RARE | Common Stock | D | 1,390 | 15,896 | ||||||
| 2019-04-17 | 2019-03-05 | 4/A | Kassberg Thomas Richard | RARE | Common Stock | D | 65.5200 | -832 | -55 | 89,474 | ||||
| 2019-04-17 | 2019-03-01 | 4/A | Kassberg Thomas Richard | RARE | Stock Option (Right to Buy) | D | 67.55 | 21,500 | 21,500 | |||||
| 2019-04-17 | 2019-03-01 | 4/A | Kassberg Thomas Richard | RARE | Common Stock | D | 7,000 | 90,306 | ||||||
| 2019-03-20 | 2019-03-18 | 4 | Sharp Shalini | RARE | Stock Option (Right to Buy) | D | 6.86 | -12,000 | 27,878 | |||||
| 2019-03-20 | 2019-03-18 | 4 | Sharp Shalini | RARE | Common Stock | D | 70.0000 | -14,800 | -1,036 | 66,357 | ||||
| 2019-03-20 | 2019-03-18 | 4 | Sharp Shalini | RARE | Common Stock | D | 6.8600 | 12,000 | 82 | 81,157 | ||||
| 2019-03-04 | 2019-03-01 | 4 | Bedrosian Camille L | RARE | Stock Option (Right to Buy) | D | 67.55 | 21,500 | 21,500 | |||||
| 2019-03-04 | 2019-03-01 | 4 | Bedrosian Camille L | RARE | Common Stock | D | 7,000 | 23,364 | ||||||
| 2019-03-04 | 2019-03-01 | 4 | Pinion John Richard | RARE | Stock Option (Right to Buy) | D | 67.55 | 23,000 | 23,000 | |||||
| 2019-03-04 | 2019-03-01 | 4 | Pinion John Richard | RARE | Common Stock | D | 67.5500 | -701 | -47 | 36,986 | ||||
| 2019-03-04 | 2019-03-01 | 4 | Pinion John Richard | RARE | Common Stock | D | 20,000 | 37,687 | ||||||
| 2019-03-04 | 2019-03-01 | 4 | Huang Dennis Karl | RARE | Stock Option (Right to Buy) | D | 67.55 | 20,000 | 20,000 | |||||
| 2019-03-04 | 2019-03-01 | 4 | Huang Dennis Karl | RARE | Common Stock | D | 67.5500 | -607 | -41 | 21,711 | ||||
| 2019-03-04 | 2019-03-01 | 4 | Huang Dennis Karl | RARE | Common Stock | D | 6,000 | 22,318 | ||||||
| 2019-03-04 | 2019-03-01 | 4 | Huizenga Theodore Alan | RARE | Stock Option (Right to Buy) | D | 67.55 | 6,840 | 6,840 | |||||
| 2019-03-04 | 2019-03-01 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 67.5500 | -246 | -17 | 15,649 | ||||
| 2019-03-04 | 2019-03-01 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 1,390 | 15,895 | ||||||
| 2019-03-04 | 2019-03-01 | 4 | KAKKIS EMIL D | RARE | Stock Option (Right to Buy) | D | 67.55 | 66,000 | 66,000 | |||||
| 2019-03-04 | 2019-03-01 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 67.5500 | -2,802 | -189 | 467,670 | ||||
| 2019-03-04 | 2019-03-01 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 20,000 | 470,472 | ||||||
| 2019-03-04 | 2019-03-01 | 4 | Sharp Shalini | RARE | Stock Option (Right to Buy) | D | 67.55 | 23,000 | 23,000 | |||||
| 2019-03-04 | 2019-03-01 | 4 | Sharp Shalini | RARE | Common Stock | D | 67.5500 | -981 | -66 | 69,156 | ||||
| 2019-03-04 | 2019-03-01 | 4 | Sharp Shalini | RARE | Common Stock | D | 8,000 | 70,137 | ||||||
| 2019-03-04 | 2019-03-01 | 4 | Parschauer Karah Herdman | RARE | Stock Option (Right to Buy) | D | 67.55 | 21,500 | 21,500 | |||||
| 2019-03-04 | 2019-03-01 | 4 | Parschauer Karah Herdman | RARE | Common Stock | D | 67.5500 | -860 | -58 | 20,321 | ||||
| 2019-03-04 | 2019-03-01 | 4 | Parschauer Karah Herdman | RARE | Common Stock | D | 7,000 | 21,181 | ||||||
| 2019-03-04 | 2019-03-01 | 4 | Kassberg Thomas Richard | RARE | Stock Option (Right to Buy) | D | 67.55 | 21,500 | 21,500 | |||||
| 2019-03-04 | 2019-03-01 | 4 | Kassberg Thomas Richard | RARE | Common Stock | D | 67.5500 | -806 | -54 | 89,499 | ||||
| 2019-03-04 | 2019-03-01 | 4 | Kassberg Thomas Richard | RARE | Common Stock | D | 7,000 | 90,305 | ||||||
| 2019-03-04 | 2019-03-01 | 4 | Hogenhuis Wladimir | RARE | Stock Option (Right to Buy) | D | 67.55 | 11,000 | 11,000 | |||||
| 2019-03-04 | 2019-03-01 | 4 | Hogenhuis Wladimir | RARE | Common Stock | D | 5,000 | 20,000 | ||||||
| 2019-02-15 | 2019-01-30 | 4 | Bedrosian Camille L | RARE | Common Stock | D | 48.8500 | -1,636 | -80 | 16,364 | ||||
| 2019-02-01 | 2019-01-30 | 4 | SULIMAN SHEHNAAZ | RARE | Stock Option (Right to Buy) | D | 48.85 | 20,000 | 20,000 | |||||
| 2019-01-02 | 2019-01-02 | 4 | Huizenga Theodore Alan | RARE | Stock Option (Right to Buy) | D | 21.00 | -2,448 | 17,000 | |||||
| 2019-01-02 | 2019-01-02 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 21.0000 | 2,448 | 51 | 14,505 | ||||
| 2018-12-07 | 2018-12-07 | 4 | Aliski William By trust | RARE | Common Stock | I | 49.6900 | -6,000 | -298 | 90,350 | ||||
| 2018-11-08 | 2018-11-08 | 4 | Aliski William By trust | RARE | Common Stock | I | 55.6700 | -6,000 | -334 | 96,350 | ||||
| 2018-10-31 | 2018-10-31 | 4 | Sharp Shalini | RARE | Stock Option (Right to Buy) | D | 0.82 | -12,000 | 6,963 | |||||
| 2018-10-31 | 2018-10-31 | 4 | Sharp Shalini | RARE | Common Stock | D | 0.8150 | 12,000 | 10 | 62,128 | ||||
| 2018-10-09 | 3/A | Aliski William By trust | RARE | Common Stock | I | 36,930 | ||||||||
| 2018-10-09 | 2018-08-21 | 4/A | Parschauer Karah Herdman | RARE | Stock Option (Right to Buy) | D | 54.50 | -5,000 | 55,000 | |||||
| 2018-10-09 | 2018-08-21 | 4/A | Parschauer Karah Herdman | RARE | Common Stock | D | 78.5300 | -5,000 | -393 | 14,181 | ||||
| 2018-10-09 | 2018-08-21 | 4/A | Parschauer Karah Herdman | RARE | Common Stock | D | 54.5000 | 5,000 | 272 | 19,181 | ||||
| 2018-10-09 | 2018-10-04 | 4 | Hogenhuis Wladimir | RARE | Stock Option (Right to Buy) | D | 77.30 | 75,000 | 75,000 | |||||
| 2018-10-09 | 2018-10-04 | 4 | Hogenhuis Wladimir | RARE | Common Stock | D | 15,000 | 15,000 | ||||||
| 2018-10-09 | 2018-10-08 | 4 | Aliski William By trust | RARE | Common Stock | I | 73.3800 | -6,000 | -440 | 102,350 | ||||
| 2018-10-09 | 2018-04-19 | 4 | Aliski William By trust | RARE | Common Stocki | I | 53.9700 | -650 | -35 | 108,350 | ||||
| 2018-10-09 | 2015-07-27 | 4 | Aliski William By trust | RARE | Common Stock | I | 122.5800 | -400 | -49 | 109,000 | ||||
| 2018-10-09 | 2015-05-27 | 4 | Aliski William By trust | RARE | Common Stock | I | 85.9400 | -2,000 | -172 | 109,400 | ||||
| 2018-10-09 | 2015-05-12 | 4 | Aliski William By trust | RARE | Common Stock | I | 68.6500 | -10,500 | -721 | 111,400 | ||||
| 2018-10-09 | 2014-02-05 | 4 | Aliski William By trust | RARE | Series A Preferred Stock | I | -266,343 | 0 | ||||||
| 2018-10-09 | 2014-02-05 | 4 | Aliski William By trust | RARE | Common Stock | I | 84,970 | 121,900 | ||||||
| 2018-09-27 | 2018-09-25 | 4 | Sharp Shalini | RARE | Stock Option (Right to Buy) | D | 0.82 | -3,350 | 18,963 | |||||
| 2018-09-27 | 2018-09-25 | 4 | Sharp Shalini | RARE | Common Stock | D | 90.0700 | -6,700 | -603 | 50,128 | ||||
| 2018-09-27 | 2018-09-25 | 4 | Sharp Shalini | RARE | Common Stock | D | 0.8150 | 3,350 | 3 | 56,828 | ||||
| 2018-08-21 | 2018-08-21 | 4 | Parschauer Karah Herdman | RARE | Common Stock | D | 78.5300 | -5,000 | -393 | 9,181 | ||||
| 2018-08-08 | 2018-08-08 | 4 | Aliski William | RARE | Common Stock | D | 76.6600 | -3,750 | -287 | 72,610 | ||||
| 2018-07-16 | 2018-07-16 | 4 | Pinion John Richard | RARE | Common Stock | D | 84.3500 | -649 | -55 | 17,681 | ||||
| 2018-06-21 | 2018-06-21 | 4 | Parschauer Karah Herdman | RARE | Common Stock | D | 82.7700 | -1,226 | -101 | 14,181 | ||||
| 2018-06-20 | 2018-06-20 | 4 | Parschauer Karah Herdman | RARE | Common Stock | D | 85.3100 | -649 | -55 | 15,407 | ||||
| 2018-06-20 | 2018-06-19 | 4 | NARACHI MICHAEL | RARE | Stock Option (Right to Buy) | D | 80.69 | 5,000 | 5,000 | |||||
| 2018-06-20 | 2018-06-19 | 4 | NARACHI MICHAEL | RARE | Common Stock | D | 3,000 | 6,750 | ||||||
| 2018-06-20 | 2018-06-19 | 4 | SIEGALL CLAY B | RARE | Stock Option (Right to Buy) | D | 80.69 | 5,000 | 5,000 | |||||
| 2018-06-20 | 2018-06-19 | 4 | SIEGALL CLAY B | RARE | Common Stock | D | 3,000 | 6,750 | ||||||
| 2018-06-20 | 2018-06-19 | 4 | Dunsire Deborah | RARE | Stock Option (Right to Buy) | D | 80.69 | 5,000 | 5,000 | |||||
| 2018-06-20 | 2018-06-19 | 4 | Dunsire Deborah | RARE | Common Stock | D | 3,000 | 4,875 | ||||||
| 2018-06-20 | 2018-06-19 | 4 | Fust Matthew K | RARE | Stock Option (Right to Buy) | D | 80.69 | 5,000 | 5,000 | |||||
| 2018-06-20 | 2018-06-19 | 4 | Fust Matthew K | RARE | Common Stock | D | 3,000 | 11,750 | ||||||
| 2018-06-20 | 2018-06-19 | 4 | Aliski William | RARE | Stock Option (Right to Buy) | D | 80.69 | 5,000 | 5,000 | |||||
| 2018-06-20 | 2018-06-19 | 4 | Aliski William | RARE | Common Stock | D | 3,000 | 76,360 | ||||||
| 2018-06-20 | 2018-06-19 | 4 | Ekman Lars | RARE | Stock Option (Right to Buy) | D | 80.69 | 5,000 | 5,000 | |||||
| 2018-06-20 | 2018-06-19 | 4 | Ekman Lars | RARE | Common Stock | D | 3,000 | 6,750 | ||||||
| 2018-06-20 | 2018-06-19 | 4 | WELCH DANIEL G | RARE | Stock Option (Right to Buy) | D | 80.69 | 5,000 | 5,000 | |||||
| 2018-06-20 | 2018-06-19 | 4 | WELCH DANIEL G | RARE | Common Stock | D | 3,000 | 6,750 | ||||||
| 2018-06-15 | 2018-06-15 | 4 | Huizenga Theodore Alan | RARE | Stock Option (Right to Buy) | D | 21.00 | -2,955 | 19,448 | |||||
| 2018-06-15 | 2018-06-15 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 83.7000 | -955 | -80 | 11,940 | ||||
| 2018-06-15 | 2018-06-15 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 21.0000 | 2,955 | 62 | 12,895 | ||||
| 2018-06-13 | 2018-06-13 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 76.9700 | -1,338 | -103 | 9,940 | ||||
| 2018-06-07 | 2018-06-07 | 4 | Sharp Shalini | RARE | Stock Option (Right to Buy) | D | 0.82 | -3,350 | 22,313 | |||||
| 2018-06-07 | 2018-06-07 | 4 | Sharp Shalini | RARE | Common Stock | D | 80.0680 | -6,700 | -536 | 53,478 | ||||
| 2018-06-07 | 2018-06-07 | 4 | Sharp Shalini | RARE | Common Stock | D | 0.8150 | 3,350 | 3 | 60,178 | ||||
| 2018-06-04 | 2018-06-01 | 4 | Huang Dennis Karl | RARE | Common Stock | D | 73.7300 | -260 | -19 | 16,124 | ||||
| 2018-06-04 | 2018-06-01 | 4 | Sharp Shalini | RARE | Common Stock | D | 73.7300 | -346 | -26 | 56,828 | ||||
| 2018-06-04 | 2018-06-01 | 4 | Pinion John Richard | RARE | Common Stock | D | 73.7300 | -260 | -19 | 18,330 | ||||
| 2018-06-04 | 2018-06-01 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 73.7300 | -926 | -68 | 450,472 | ||||
| 2018-06-04 | 2018-06-01 | 4 | Kassberg Thomas Richard | RARE | Common Stock | D | 73.7300 | -346 | -26 | 83,114 | ||||
| 2018-06-04 | 2018-06-01 | 4 | Dallas Jayson Donald Alexander | RARE | Common Stock | D | 73.7300 | -294 | -22 | 23,830 | ||||
| 2018-05-30 | 2018-05-30 | 4 | Fust Matthew K | RARE | Common Stock | D | 72.0002 | -6,319 | -455 | 8,750 | ||||
| 2018-05-30 | 2018-05-30 | 4 | Sharp Shalini | RARE | Stock Option (Right to Buy) | D | 0.82 | -6,500 | 25,663 | |||||
| 2018-05-30 | 2018-05-30 | 4 | Sharp Shalini | RARE | Common Stock | D | 70.1670 | -13,000 | -912 | 57,174 | ||||
| 2018-05-30 | 2018-05-30 | 4 | Sharp Shalini | RARE | Common Stock | D | 0.8150 | 6,500 | 5 | 70,174 | ||||
| 2018-05-29 | 2018-05-25 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 67.3100 | -433 | -29 | 11,278 | ||||
| 2018-05-22 | 2018-05-21 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 64.7900 | -156 | -10 | 11,711 | ||||
| 2018-05-22 | 2018-05-21 | 4 | Kassberg Thomas Richard | RARE | Common Stock | D | 64.7900 | -381 | -25 | 83,460 | ||||
| 2018-05-22 | 2018-05-21 | 4 | Sharp Shalini | RARE | Common Stock | D | 64.7900 | -381 | -25 | 63,674 | ||||
| 2018-05-22 | 2018-05-21 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 64.7900 | -986 | -64 | 451,398 | ||||
| 2018-05-10 | 2018-05-10 | 4 | Parschauer Karah Herdman | RARE | Common Stock | D | 60.0000 | -1,465 | -88 | 16,056 | ||||
| 2018-05-08 | 2018-05-05 | 4 | Huang Dennis Karl | RARE | Common Stock | D | 54.5000 | -649 | -35 | 16,384 | ||||
| 2018-04-19 | 2018-04-19 | 4 | Parschauer Karah Herdman | RARE | Common Stock | D | 1,431 | 17,521 | ||||||
| 2018-04-19 | 2018-04-19 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 799 | 11,474 | ||||||
| 2018-04-19 | 2018-04-19 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 3,429 | 452,384 | ||||||
| 2018-04-19 | 2018-04-19 | 4 | Sharp Shalini | RARE | Common Stock | D | 1,431 | 63,544 | ||||||
| 2018-04-19 | 2018-04-19 | 4 | Kassberg Thomas Richard | RARE | Common Stock | D | 1,431 | 83,529 | ||||||
| 2018-04-19 | 2018-04-19 | 4 | Dallas Jayson Donald Alexander | RARE | Common Stock | D | 1,431 | 23,604 | ||||||
| 2018-04-19 | 2018-04-19 | 4 | Huang Dennis Karl | RARE | Common Stock | D | 1,431 | 16,850 | ||||||
| 2018-04-19 | 2018-04-19 | 4 | Pinion John Richard | RARE | Common Stock | D | 1,431 | 18,076 | ||||||
| 2018-03-05 | 2018-03-01 | 4 | Pinion John Richard | RARE | Stock Option (Right to Buy) | D | 48.43 | 27,000 | 27,000 | |||||
| 2018-03-05 | 2018-03-01 | 4 | Pinion John Richard | RARE | Common Stock | D | 48.4300 | -276 | -13 | 16,645 | ||||
| 2018-03-05 | 2018-03-01 | 4 | Pinion John Richard | RARE | Common Stock | D | 5,000 | 16,921 | ||||||
| 2018-03-05 | 2018-03-01 | 4 | Parschauer Karah Herdman | RARE | Stock Option (Right to Buy) | D | 48.43 | 37,000 | 37,000 | |||||
| 2018-03-05 | 2018-03-01 | 4 | Parschauer Karah Herdman | RARE | Common Stock | D | 48.4300 | -205 | -10 | 16,090 | ||||
| 2018-03-05 | 2018-03-01 | 4 | Parschauer Karah Herdman | RARE | Common Stock | D | 7,500 | 16,295 | ||||||
| 2018-03-05 | 2018-03-01 | 4 | Huang Dennis Karl | RARE | Stock Option (Right to Buy) | D | 48.43 | 25,000 | 25,000 | |||||
| 2018-03-05 | 2018-03-01 | 4 | Huang Dennis Karl | RARE | Common Stock | D | 48.4300 | -205 | -10 | 15,419 | ||||
| 2018-03-05 | 2018-03-01 | 4 | Huang Dennis Karl | RARE | Common Stock | D | 4,500 | 15,624 | ||||||
| 2018-03-05 | 2018-03-01 | 4 | Huizenga Theodore Alan | RARE | Stock Option (Right to Buy) | D | 48.43 | 7,975 | 7,975 | |||||
| 2018-03-05 | 2018-03-01 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 48.4300 | -110 | -5 | 10,675 | ||||
| 2018-03-05 | 2018-03-01 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 1,313 | 10,785 | ||||||
| 2018-03-05 | 2018-03-01 | 4 | KAKKIS EMIL D | RARE | Stock Option (Right to Buy) | D | 48.43 | 94,500 | 94,500 | |||||
| 2018-03-05 | 2018-03-01 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 48.4300 | -1,114 | -54 | 448,955 | ||||
| 2018-03-05 | 2018-03-01 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 19,500 | 450,069 | ||||||
| 2018-03-05 | 2018-03-01 | 4 | Sharp Shalini | RARE | Stock Option (Right to Buy) | D | 48.43 | 35,000 | 35,000 | |||||
| 2018-03-05 | 2018-03-01 | 4 | Sharp Shalini | RARE | Common Stock | D | 48.4300 | -397 | -19 | 62,113 | ||||
| 2018-03-05 | 2018-03-01 | 4 | Sharp Shalini | RARE | Common Stock | D | 7,000 | 62,510 | ||||||
| 2018-03-05 | 2018-03-01 | 4 | Kassberg Thomas Richard | RARE | Stock Option (Right to Buy) | D | 48.43 | 30,000 | 30,000 | |||||
| 2018-03-05 | 2018-03-01 | 4 | Kassberg Thomas Richard | RARE | Common Stock | D | 48.4300 | -307 | -15 | 82,098 | ||||
| 2018-03-05 | 2018-03-01 | 4 | Kassberg Thomas Richard | RARE | Common Stock | D | 6,000 | 82,405 | ||||||
| 2018-03-05 | 2018-03-01 | 4 | Dallas Jayson Donald Alexander | RARE | Stock Option (Right to Buy) | D | 48.43 | 32,000 | 32,000 | |||||
| 2018-03-05 | 2018-03-01 | 4 | Dallas Jayson Donald Alexander | RARE | Common Stock | D | 48.4300 | -441 | -21 | 22,173 | ||||
| 2018-03-05 | 2018-03-01 | 4 | Dallas Jayson Donald Alexander | RARE | Common Stock | D | 6,500 | 22,614 | ||||||
| 2018-01-31 | 2018-01-30 | 4 | Bedrosian Camille L | RARE | Employee Stock Option (Right to Buy) | D | 55.00 | 88,000 | 88,000 | |||||
| 2018-01-31 | 2018-01-30 | 4 | Bedrosian Camille L | RARE | Common Stock | D | 18,000 | 18,000 | ||||||
| 2018-01-25 | 2018-01-23 | 4 | Aliski William | RARE | Employee Stock Option (Right to Buy) | D | 21.00 | -11,500 | 0 | |||||
| 2018-01-25 | 2018-01-23 | 4 | Aliski William | RARE | Common Stock | D | 21.0000 | 11,500 | 242 | 73,360 | ||||
| 2017-08-29 | 2017-08-28 | 4 | KAKKIS EMIL D By Emil Kakkis and Jenny Soriano Living Trust, dated June 18, 2009 | RARE | Common Stock | I | 52.9600 | 1,647 | 87 | 2,559,741 | ||||
| 2017-08-29 | 2017-08-28 | 4 | KAKKIS EMIL D By Emil Kakkis and Jenny Soriano Living Trust, dated June 18, 2009 | RARE | Common Stock | I | 52.4000 | 5,853 | 307 | 2,558,094 | ||||
| 2017-08-07 | 2017-08-03 | 4 | Dallas Jayson Donald Alexander | RARE | Common Stock | D | 62.5900 | -940 | -59 | 16,107 | ||||
| 2017-07-17 | 2017-07-16 | 4 | Pinion John Richard | RARE | Common Stock | D | 64.3600 | -705 | -45 | 11,883 | ||||
| 2017-06-22 | 2017-06-22 | 4 | SIEGALL CLAY B | RARE | Employee Stock Option (Right to Buy) | D | 65.66 | 3,750 | 3,750 | |||||
| 2017-06-22 | 2017-06-22 | 4 | SIEGALL CLAY B | RARE | Common Stock | D | 1,875 | 3,750 | ||||||
| 2017-06-22 | 2017-06-22 | 4 | WELCH DANIEL G | RARE | Employee Stock Option (Right to Buy) | D | 65.66 | 3,750 | 3,750 | |||||
| 2017-06-22 | 2017-06-22 | 4 | WELCH DANIEL G | RARE | Common Stock | D | 1,875 | 3,750 | ||||||
| 2017-06-22 | 2017-06-22 | 4 | Fust Matthew K | RARE | Employee Stock Option (Right to Buy) | D | 65.66 | 3,750 | 3,750 | |||||
| 2017-06-22 | 2017-06-22 | 4 | Fust Matthew K | RARE | Common Stock | D | 1,875 | 15,069 | ||||||
| 2017-06-22 | 2017-06-22 | 4 | NARACHI MICHAEL | RARE | Employee Stock Option (Right to Buy) | D | 65.66 | 3,750 | 3,750 | |||||
| 2017-06-22 | 2017-06-22 | 4 | NARACHI MICHAEL | RARE | Common Stock | D | 1,875 | 3,750 | ||||||
| 2017-06-22 | 2017-06-22 | 4 | Dunsire Deborah | RARE | Employee Stock Option (Right to Buy) | D | 65.66 | 3,750 | 3,750 | |||||
| 2017-06-22 | 2017-06-22 | 4 | Dunsire Deborah | RARE | Common Stock | D | 1,875 | 1,875 | ||||||
| 2017-06-22 | 2017-06-22 | 4 | Ekman Lars | RARE | Employee Stock Option (Right to Buy) | D | 65.66 | 3,750 | 3,750 | |||||
| 2017-06-22 | 2017-06-22 | 4 | Ekman Lars | RARE | Common Stock | D | 1,875 | 3,750 | ||||||
| 2017-06-22 | 2017-06-22 | 4 | Aliski William | RARE | Employee Stock Option (Right to Buy) | D | 65.66 | 3,750 | 3,750 | |||||
| 2017-06-22 | 2017-06-22 | 4 | Aliski William | RARE | Common Stock | D | 1,875 | 61,860 | ||||||
| 2017-06-21 | 2017-06-20 | 4 | Parschauer Karah Herdman | RARE | Common Stock | D | 63.3800 | -705 | -45 | 8,795 | ||||
| 2017-06-01 | 2017-06-01 | 4 | Huang Dennis Karl | RARE | Common Stock | D | 56.6100 | -282 | -16 | 10,939 | ||||
| 2017-06-01 | 2017-06-01 | 4 | Dallas Jayson Donald Alexander | RARE | Common Stock | D | 56.6100 | -320 | -18 | 17,047 | ||||
| 2017-06-01 | 2017-06-01 | 4 | Kassberg Thomas Richard | RARE | Common Stock | D | 56.6100 | -376 | -21 | 76,228 | ||||
| 2017-06-01 | 2017-06-01 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 56.6100 | -1,006 | -57 | 430,569 | ||||
| 2017-06-01 | 2017-06-01 | 4 | Sharp Shalini | RARE | Common Stock | D | 56.6100 | -376 | -21 | 55,470 | ||||
| 2017-06-01 | 2017-06-01 | 4 | Pinion John Richard | RARE | Common Stock | D | 56.6100 | -282 | -16 | 12,588 | ||||
| 2017-05-26 | 2017-05-26 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 57.4600 | -480 | -28 | 9,366 | ||||
| 2017-05-22 | 2017-05-21 | 4 | Sharp Shalini | RARE | Common Stock | D | 57.4700 | -414 | -24 | 55,846 | ||||
| 2017-05-22 | 2017-05-21 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 57.4700 | -1,072 | -62 | 431,575 | ||||
| 2017-05-22 | 2017-05-21 | 4 | Kassberg Thomas Richard | RARE | Common Stock | D | 57.4700 | -414 | -24 | 76,604 | ||||
| 2017-05-22 | 2017-05-21 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 57.4700 | -166 | -10 | 9,846 | ||||
| 2017-05-08 | 2017-05-05 | 4 | Huang Dennis Karl | RARE | Common Stock | D | 61.0800 | -705 | -43 | 11,221 | ||||
| 2017-04-10 | 2017-04-06 | 4 | Dunsire Deborah | RARE | Stock Option (Right to Buy) | D | 58.59 | 15,000 | 15,000 | |||||
| 2017-03-10 | 2017-03-09 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 86.3380 | -2,500 | -216 | 9,709 | ||||
| 2017-03-03 | 2017-03-02 | 4 | Sharp Shalini | RARE | Stock Option (Right to Buy) | D | 0.82 | -12,000 | 32,163 | |||||
| 2017-03-03 | 2017-03-02 | 4 | Sharp Shalini | RARE | Common Stock | D | 90.0980 | -12,000 | -1,081 | 55,887 | ||||
| 2017-03-03 | 2017-03-02 | 4 | Sharp Shalini | RARE | Common Stock | D | 0.8150 | 12,000 | 10 | 67,887 | ||||
| 2017-03-02 | 2017-03-01 | 4 | Huizenga Theodore Alan | RARE | Employee Stock Option (Right to Buy) | D | 88.80 | 6,450 | 6,450 | |||||
| 2017-03-02 | 2017-03-01 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 1,075 | 12,209 | ||||||
| 2017-03-01 | 2017-03-01 | 4 | Pinion John Richard | RARE | Employee Stock Option (Right to Buy) | D | 88.80 | 18,000 | 18,000 | |||||
| 2017-03-01 | 2017-03-01 | 4 | Pinion John Richard | RARE | Common Stock | D | 2,700 | 12,495 | ||||||
| 2017-03-01 | 2017-03-01 | 4 | Sharp Shalini | RARE | Stock Option (Right to Buy) | D | 88.80 | 28,000 | 28,000 | |||||
| 2017-03-01 | 2017-03-01 | 4 | Sharp Shalini | RARE | Common Stock | D | 4,000 | 55,887 | ||||||
| 2017-03-01 | 2017-03-01 | 4 | Kassberg Thomas Richard | RARE | Employee Stock Option (Right to Buy) | D | 88.80 | 25,000 | 25,000 | |||||
| 2017-03-01 | 2017-03-01 | 4 | Kassberg Thomas Richard | RARE | Common Stock | D | 3,000 | 76,790 | ||||||
| 2017-03-01 | 2017-03-01 | 4 | Parschauer Karah Herdman | RARE | Employee Stock Option (Right to Buy) | D | 88.80 | 12,000 | 12,000 | |||||
| 2017-03-01 | 2017-03-01 | 4 | Parschauer Karah Herdman | RARE | Common Stock | D | 2,000 | 9,500 | ||||||
| 2017-03-01 | 2017-03-01 | 4 | KAKKIS EMIL D | RARE | Employee Stock Option (Right to Buy) | D | 88.80 | 78,000 | 78,000 | |||||
| 2017-03-01 | 2017-03-01 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 13,000 | 432,647 | ||||||
| 2017-03-01 | 2017-03-01 | 4 | Huang Dennis Karl | RARE | Employee Stock Option (RIght to Buy) | D | 88.80 | 15,000 | 15,000 | |||||
| 2017-03-01 | 2017-03-01 | 4 | Huang Dennis Karl | RARE | Common Stock | D | 2,000 | 11,795 | ||||||
| 2017-03-01 | 2017-03-01 | 4 | Dallas Jayson Donald Alexander | RARE | Employee Stock Option (Right to Buy) | D | 88.80 | 30,000 | 30,000 | |||||
| 2017-03-01 | 2017-03-01 | 4 | Dallas Jayson Donald Alexander | RARE | Common Stock | D | 4,500 | 16,960 | ||||||
| 2017-02-28 | 2017-02-27 | 4 | Sharp Shalini | RARE | Stock Option (Right to Buy) | D | 0.82 | -12,000 | 44,163 | |||||
| 2017-02-28 | 2017-02-27 | 4 | Sharp Shalini | RARE | Common Stock | D | 80.1400 | -12,000 | -962 | 51,887 | ||||
| 2017-02-28 | 2017-02-27 | 4 | Sharp Shalini | RARE | Common Stock | D | 0.8150 | 12,000 | 10 | 63,887 | ||||
| 2017-02-10 | 2016-12-22 | 5 | KAKKIS EMIL D | RARE | Common Stock | D | -27,500 | 419,647 | ||||||
| 2016-12-23 | 2016-12-23 | 4 | Sharp Shalini | RARE | Stock Option (Right to Buy) | D | 0.82 | -6,500 | 56,163 | |||||
| 2016-12-23 | 2016-12-23 | 4 | Sharp Shalini | RARE | Common Stock | D | 0.8100 | 6,500 | 5 | 51,887 | ||||
| 2016-12-05 | 2016-12-05 | 4 | Aliski William | RARE | Employee Stock Option (Right to Buy) | D | 21.00 | -6,000 | 11,500 | |||||
| 2016-12-05 | 2016-12-05 | 4 | Aliski William | RARE | Common Stock | D | 78.7000 | -2,000 | -157 | 59,985 | ||||
| 2016-12-05 | 2016-12-05 | 4 | Aliski William | RARE | Common Stock | D | 77.9400 | -4,000 | -312 | 61,985 | ||||
| 2016-12-05 | 2016-12-05 | 4 | Aliski William | RARE | Common Stock | D | 21.0000 | 6,000 | 126 | 65,985 | ||||
| 2016-11-18 | 2015-06-17 | 4/A | Huizenga Theodore Alan | RARE | Common Stock | D | 94.8000 | -1,500 | -142 | 4,300 | ||||
| 2016-11-18 | 2015-06-17 | 4/A | Huizenga Theodore Alan | RARE | Common Stock | D | 21.0000 | 1,500 | 32 | 5,800 | ||||
| 2016-11-18 | 2016-11-16 | 4 | Huizenga Theodore Alan | RARE | Stock Options (Right to buy) | D | 21.00 | -2,000 | 22,403 | |||||
| 2016-11-18 | 2016-11-16 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 79.7300 | -2,000 | -159 | 11,134 | ||||
| 2016-11-18 | 2016-11-16 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 21.0000 | 2,000 | 42 | 13,134 | ||||
| 2016-11-17 | 2016-11-15 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 83.0100 | -200 | -17 | 447,147 | ||||
| 2016-11-17 | 2016-11-15 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 82.3600 | -4,180 | -344 | 447,347 | ||||
| 2016-11-17 | 2016-11-15 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 81.5500 | -7,755 | -632 | 451,527 | ||||
| 2016-11-17 | 2016-11-15 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 80.6400 | -6,451 | -520 | 459,282 | ||||
| 2016-11-17 | 2016-11-15 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 79.3900 | -1,414 | -112 | 465,733 | ||||
| 2016-11-10 | 2016-11-09 | 4 | Sharp Shalini | RARE | Stock Option | D | 0.82 | -24,000 | 62,663 | |||||
| 2016-11-10 | 2016-11-09 | 4 | Sharp Shalini | RARE | Common Stock | D | 74.3400 | -700 | -52 | 45,387 | ||||
| 2016-11-10 | 2016-11-09 | 4 | Sharp Shalini | RARE | Common Stock | D | 73.6500 | -2,600 | -191 | 46,087 | ||||
| 2016-11-10 | 2016-11-09 | 4 | Sharp Shalini | RARE | Common Stock | D | 72.8100 | -3,205 | -233 | 48,687 | ||||
| 2016-11-10 | 2016-11-09 | 4 | Sharp Shalini | RARE | Common Stock | D | 71.6800 | -3,895 | -279 | 51,892 | ||||
| 2016-11-10 | 2016-11-09 | 4 | Sharp Shalini | RARE | Common Stock | D | 70.0600 | -13,600 | -953 | 55,787 | ||||
| 2016-11-10 | 2016-11-09 | 4 | Sharp Shalini | RARE | Common Stock | D | 0.8150 | 24,000 | 20 | 69,387 | ||||
| 2016-10-21 | 2016-10-19 | 4 | Sharp Shalini | RARE | Stock Option | D | 0.82 | -12,000 | 86,663 | |||||
| 2016-10-21 | 2016-10-19 | 4 | Sharp Shalini | RARE | Common Stock | D | 61.7100 | -6,932 | -428 | 45,387 | ||||
| 2016-10-21 | 2016-10-19 | 4 | Sharp Shalini | RARE | Common Stock | D | 60.9800 | -5,068 | -309 | 52,319 | ||||
| 2016-10-21 | 2016-10-19 | 4 | Sharp Shalini | RARE | Common Stock | D | 0.8150 | 12,000 | 10 | 57,387 | ||||
| 2016-10-18 | 2016-10-14 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 64.7800 | -1,800 | -117 | 467,147 | ||||
| 2016-10-18 | 2016-10-14 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 64.4100 | -2,345 | -151 | 468,947 | ||||
| 2016-10-18 | 2016-10-14 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 63.0600 | -9,340 | -589 | 471,292 | ||||
| 2016-10-18 | 2016-10-14 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 61.9700 | -6,515 | -404 | 480,632 | ||||
| 2016-08-23 | 2016-08-19 | 4 | AGARWAL SUNIL | RARE | Common Stock | D | 66.0000 | -392 | -26 | 9,136 | ||||
| 2016-08-17 | 2016-08-15 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 68.1200 | -6,097 | -415 | 487,147 | ||||
| 2016-08-17 | 2016-08-15 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 67.3900 | -13,903 | -937 | 493,244 | ||||
| 2016-08-08 | 2016-08-04 | 4 | Dallas Jayson Donald Alexander | RARE | Common Stock | D | 64.2400 | -940 | -60 | 12,460 | ||||
| 2016-07-21 | 2016-07-21 | 4 | AGARWAL SUNIL | RARE | Common Stock | D | 52.6800 | -649 | -34 | 9,528 | ||||
| 2016-07-21 | 2016-07-19 | 4 | AGARWAL SUNIL | RARE | Common Stock | D | 50.5500 | -392 | -20 | 10,177 | ||||
| 2016-07-19 | 2016-07-15 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 51.3400 | -6,450 | -331 | 507,147 | ||||
| 2016-07-19 | 2016-07-15 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 50.6100 | -13,550 | -686 | 513,597 | ||||
| 2016-07-19 | 2016-07-16 | 4 | Pinion John Richard | RARE | Common Stock | D | 53.1700 | -705 | -37 | 9,795 | ||||
| 2016-06-22 | 2016-06-20 | 4 | Parschauer Karah Herdman | RARE | Employee Stock Option (Right to Buy) | D | 54.50 | 60,000 | 60,000 | |||||
| 2016-06-22 | 2016-06-20 | 4 | Parschauer Karah Herdman | RARE | Common Stock | D | 7,500 | 7,500 | ||||||
| 2016-06-21 | 2016-06-20 | 4 | AGARWAL SUNIL | RARE | Common Stock | D | 54.1600 | -650 | -35 | 10,569 | ||||
| 2016-06-21 | 2016-06-19 | 4 | AGARWAL SUNIL | RARE | Common Stock | D | 54.9900 | -392 | -22 | 11,219 | ||||
| 2016-06-14 | 2016-06-09 | 4 | SIEGALL CLAY B | RARE | Employee Stock Option (Right to Buy) | D | 65.85 | 3,750 | 3,750 | |||||
| 2016-06-14 | 2016-06-09 | 4 | SIEGALL CLAY B | RARE | Common Stock | D | 1,875 | 1,875 | ||||||
| 2016-06-14 | 2016-06-09 | 4 | NARACHI MICHAEL | RARE | Employee Stock Option (Right to Buy) | D | 65.85 | 3,750 | 3,750 | |||||
| 2016-06-14 | 2016-06-09 | 4 | NARACHI MICHAEL | RARE | Common Stock | D | 1,875 | 1,875 | ||||||
| 2016-06-14 | 2016-06-09 | 4 | WELCH DANIEL G | RARE | Employee Stock Option (Right to Buy) | D | 65.85 | 3,750 | 3,750 | |||||
| 2016-06-14 | 2016-06-09 | 4 | WELCH DANIEL G | RARE | Common Stock | D | 1,875 | 1,875 | ||||||
| 2016-06-14 | 2016-06-09 | 4 | Ekman Lars | RARE | Employee Stock Option (Right to Buy) | D | 65.85 | 3,750 | 3,750 | |||||
| 2016-06-14 | 2016-06-09 | 4 | Ekman Lars | RARE | Common Stock | D | 1,875 | 1,875 | ||||||
| 2016-06-14 | 2016-06-09 | 4 | Fust Matthew K | RARE | Employee Stock Option (Right to Buy) | D | 65.85 | 3,750 | 3,750 | |||||
| 2016-06-14 | 2016-06-09 | 4 | Fust Matthew K | RARE | Common Stock | D | 1,875 | 13,194 | ||||||
| 2016-06-14 | 2016-06-09 | 4 | Aliski William | RARE | Employee Stock Option (Right to Buy) | D | 65.85 | 3,750 | 3,750 | |||||
| 2016-06-14 | 2016-06-09 | 4 | Aliski William | RARE | Common Stock | D | 1,875 | 59,985 | ||||||
| 2016-06-07 | 2016-06-03 | 4 | Pinion John Richard | RARE | Employee Stock Option (Right to Buy) | D | 69.53 | 11,000 | 11,000 | |||||
| 2016-06-07 | 2016-06-03 | 4 | Dallas Jayson Donald Alexander | RARE | Employee Stock Option (Right to Buy) | D | 69.53 | 11,000 | 11,000 | |||||
| 2016-06-03 | 2016-06-01 | 4 | KAKKIS EMIL D | RARE | Employee Stock Option (Right to Buy) | D | 70.57 | 63,700 | 63,700 | |||||
| 2016-06-03 | 2016-06-01 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 10,700 | 527,147 | ||||||
| 2016-06-03 | 2016-06-01 | 4 | Kassberg Thomas Richard | RARE | Employee Stock Option (Right to Buy) | D | 70.57 | 24,000 | 24,000 | |||||
| 2016-06-03 | 2016-06-01 | 4 | Kassberg Thomas Richard | RARE | Common Stock | D | 4,000 | 73,790 | ||||||
| 2016-06-03 | 2016-06-01 | 4 | Sharp Shalini | RARE | Employee Stock Option (Right to Buy) | D | 70.57 | 24,000 | 24,000 | |||||
| 2016-06-03 | 2016-06-01 | 4 | Sharp Shalini | RARE | Common Stock | D | 4,000 | 45,387 | ||||||
| 2016-06-03 | 2016-06-01 | 4 | AGARWAL SUNIL | RARE | Employee Stock Option (Right to Buy) | D | 70.57 | 26,700 | 26,700 | |||||
| 2016-06-03 | 2016-06-01 | 4 | AGARWAL SUNIL | RARE | Common Stock | D | 4,500 | 11,611 | ||||||
| 2016-06-03 | 2016-06-01 | 4 | Huang Dennis Karl | RARE | Employee Stock Option (Right to Buy) | D | 70.57 | 17,800 | 17,800 | |||||
| 2016-06-03 | 2016-06-01 | 4 | Huang Dennis Karl | RARE | Common Stock | D | 3,000 | 9,795 | ||||||
| 2016-06-03 | 2016-06-01 | 4 | Pinion John Richard | RARE | Employee Stock Option (Right to Buy) | D | 70.57 | 17,800 | 17,800 | |||||
| 2016-06-03 | 2016-06-01 | 4 | Pinion John Richard | RARE | Common Stock | D | 3,000 | 10,500 | ||||||
| 2016-06-03 | 2016-06-01 | 4 | Dallas Jayson Donald Alexander | RARE | Employee Stock Option (Right to Buy) | D | 70.57 | 20,200 | 20,200 | |||||
| 2016-06-03 | 2016-06-01 | 4 | Dallas Jayson Donald Alexander | RARE | Common Stock | D | 3,400 | 13,400 | ||||||
| 2016-05-27 | 2016-05-25 | 4 | Huizenga Theodore Alan | RARE | Employee Stock Option (right to buy) | D | 68.59 | 10,000 | 10,000 | |||||
| 2016-05-27 | 2016-05-25 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 5,000 | 9,334 | ||||||
| 2016-05-26 | 2016-05-24 | 4 | AGARWAL SUNIL | RARE | Common Stock | D | 66.0000 | -650 | -43 | 7,111 | ||||
| 2016-05-24 | 2016-05-21 | 4 | Sharp Shalini | RARE | Common Stock | D | 64.0100 | -414 | -27 | 41,387 | ||||
| 2016-05-24 | 2016-05-21 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 64.0100 | -1,072 | -69 | 516,447 | ||||
| 2016-05-24 | 2016-05-21 | 4 | Kassberg Thomas Richard | RARE | Common Stock | D | 64.0100 | -414 | -27 | 69,790 | ||||
| 2016-05-24 | 2016-05-21 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 64.0100 | -166 | -11 | 4,334 | ||||
| 2016-05-23 | 2016-05-21 | 4 | AGARWAL SUNIL | RARE | Common Stock | D | 64.0100 | -414 | -27 | 7,761 | ||||
| 2016-05-23 | 2016-05-19 | 4 | AGARWAL SUNIL | RARE | Common Stock | D | 61.4600 | -392 | -24 | 8,175 | ||||
| 2016-05-18 | 2016-05-16 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 61.9300 | -200 | -12 | 517,519 | ||||
| 2016-05-18 | 2016-05-16 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 61.3400 | -2,595 | -159 | 517,719 | ||||
| 2016-05-18 | 2016-05-16 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 60.3200 | -6,390 | -385 | 520,314 | ||||
| 2016-05-18 | 2016-05-16 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 59.3700 | -10,815 | -642 | 526,704 | ||||
| 2016-05-09 | 2016-05-05 | 4 | Huang Dennis Karl | RARE | Common Stock | D | 62.4500 | -705 | -44 | 6,795 | ||||
| 2016-04-21 | 2016-04-20 | 4 | AGARWAL SUNIL | RARE | Common Stock | D | 70.5300 | -649 | -46 | 8,567 | ||||
| 2016-04-21 | 2016-04-19 | 4 | AGARWAL SUNIL | RARE | Common Stock | D | 69.8600 | -392 | -27 | 9,216 | ||||
| 2016-04-19 | 2016-04-15 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 71.0600 | -5,376 | -382 | 537,519 | ||||
| 2016-04-19 | 2016-04-15 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 70.3500 | -9,834 | -692 | 542,895 | ||||
| 2016-04-19 | 2016-04-15 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 69.4600 | -4,790 | -333 | 552,729 | ||||
| 2016-03-24 | 2016-03-22 | 4 | AGARWAL SUNIL | RARE | Common Stock | D | 61.4500 | -650 | -40 | 9,608 | ||||
| 2016-03-22 | 2016-03-19 | 4 | AGARWAL SUNIL | RARE | Common Stock | D | 56.3200 | -392 | -22 | 10,258 | ||||
| 2016-03-21 | 2016-03-17 | 4 | Ekman Lars | RARE | Stock Option (Right to Buy) | D | 54.28 | 15,000 | 15,000 | |||||
| 2016-02-23 | 2016-02-22 | 4 | AGARWAL SUNIL | RARE | Common Stock | D | 63.4800 | -658 | -42 | 10,650 | ||||
| 2016-02-23 | 2016-02-19 | 4 | AGARWAL SUNIL | RARE | Common Stock | D | 63.2700 | -384 | -24 | 11,308 | ||||
| 2016-02-17 | 2016-02-12 | 4 | Huizenga Theodore Alan | RARE | Stock Option | D | 21.00 | -1,000 | 24,403 | |||||
| 2016-02-17 | 2016-02-12 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 21.0000 | 1,000 | 21 | 4,500 | ||||
| 2016-02-12 | 2015-12-18 | 5 | KAKKIS EMIL D | RARE | Common Stock | D | -18,121 | 557,519 | ||||||
| 2016-02-12 | 2015-12-29 | 5 | Aliski William | RARE | Common Stock | D | -1,900 | 58,110 | ||||||
| 2016-01-21 | 2016-01-20 | 4 | AGARWAL SUNIL | RARE | Common Stock | D | 72.8300 | -585 | -43 | 12,190 | ||||
| 2016-01-21 | 2016-01-19 | 4 | AGARWAL SUNIL | RARE | Common Stock | D | 71.5200 | -456 | -33 | 12,775 | ||||
| 2016-01-19 | 2016-01-14 | 4 | Huizenga Theodore Alan | RARE | Stock Option | D | 21.00 | -1,000 | 25,403 | |||||
| 2016-01-19 | 2016-01-14 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 21.0000 | 1,000 | 21 | 3,500 | ||||
| 2016-01-04 | 2015-12-31 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 114.6100 | -605 | -69 | 575,640 | ||||
| 2016-01-04 | 2015-12-31 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 113.8300 | -2,702 | -308 | 576,245 | ||||
| 2016-01-04 | 2015-12-31 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 112.9100 | -2,191 | -247 | 578,947 | ||||
| 2016-01-04 | 2015-12-30 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 116.3100 | -2,600 | -302 | 581,138 | ||||
| 2016-01-04 | 2015-12-30 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 115.5600 | -3,600 | -416 | 583,738 | ||||
| 2016-01-04 | 2015-12-30 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 114.6100 | -5,465 | -626 | 587,338 | ||||
| 2016-01-04 | 2015-12-30 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 113.3000 | -2,837 | -321 | 592,803 | ||||
| 2015-12-24 | 2015-12-22 | 4 | AGARWAL SUNIL | RARE | Common Stock | D | 114.8100 | -498 | -57 | 13,231 | ||||
| 2015-12-22 | 2015-12-19 | 4 | AGARWAL SUNIL | RARE | Common Stock | D | 109.8700 | -544 | -60 | 13,729 | ||||
| 2015-12-18 | 2015-12-18 | 4 | Huizenga Theodore Alan | RARE | Stock Option | D | 21.00 | -1,500 | 13,955 | |||||
| 2015-12-18 | 2015-12-18 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 110.5500 | -1,500 | -166 | 2,500 | ||||
| 2015-12-18 | 2015-12-18 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 21.0000 | 1,500 | 32 | 4,000 | ||||
| 2015-12-14 | 2015-12-10 | 4 | Sharp Shalini | RARE | Stock Option | D | 0.82 | -12,000 | 98,663 | |||||
| 2015-12-14 | 2015-12-10 | 4 | Sharp Shalini | RARE | Common Stock | D | 101.0300 | -5,277 | -533 | 41,801 | ||||
| 2015-12-14 | 2015-12-10 | 4 | Sharp Shalini | RARE | Common Stock | D | 102.1600 | -6,723 | -687 | 47,078 | ||||
| 2015-12-14 | 2015-12-10 | 4 | Sharp Shalini | RARE | Common Stock | D | 0.8150 | 12,000 | 10 | 53,801 | ||||
| 2015-12-02 | 2015-11-30 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 99.4200 | -1,415 | -141 | 595,640 | ||||
| 2015-12-02 | 2015-11-30 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 98.6200 | -11,374 | -1,122 | 597,055 | ||||
| 2015-12-02 | 2015-11-30 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 97.8800 | -5,261 | -515 | 608,429 | ||||
| 2015-12-02 | 2015-11-30 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 96.4600 | -1,950 | -188 | 613,690 | ||||
| 2015-11-24 | 2015-11-23 | 4 | AGARWAL SUNIL | RARE | Common Stock | D | 95.8800 | -498 | -48 | 13,775 | ||||
| 2015-11-23 | 2015-11-19 | 4 | AGARWAL SUNIL | RARE | Common Stock | D | 97.7100 | -544 | -53 | 14,273 | ||||
| 2015-11-03 | 2015-10-30 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 101.2000 | -1,900 | -192 | 615,640 | ||||
| 2015-11-03 | 2015-10-30 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 100.4300 | -4,400 | -442 | 617,540 | ||||
| 2015-11-03 | 2015-10-30 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 99.4200 | -7,600 | -756 | 621,940 | ||||
| 2015-11-03 | 2015-10-30 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 98.6300 | -6,100 | -602 | 629,540 | ||||
| 2015-10-21 | 2015-10-20 | 4 | AGARWAL SUNIL | RARE | Common Stock | D | 85.5100 | -649 | -55 | 14,817 | ||||
| 2015-10-21 | 2015-10-19 | 4 | AGARWAL SUNIL | RARE | Common Stock | D | 88.9400 | -392 | -35 | 15,466 | ||||
| 2015-09-24 | 2015-09-22 | 4 | AGARWAL SUNIL | RARE | Common Stock | D | 109.5100 | -498 | -55 | 15,858 | ||||
| 2015-09-21 | 2015-09-19 | 4 | AGARWAL SUNIL | RARE | Common Stock | D | 129.9100 | -544 | -71 | 16,356 | ||||
| 2015-08-21 | 2015-08-20 | 4 | AGARWAL SUNIL | RARE | Stock Option (Right to Buy) | D | 55.88 | -10,000 | 140,000 | |||||
| 2015-08-21 | 2015-08-20 | 4 | AGARWAL SUNIL | RARE | Common Stock | D | 111.9035 | -930 | -104 | 16,900 | ||||
| 2015-08-21 | 2015-08-20 | 4 | AGARWAL SUNIL | RARE | Common Stock | D | 111.2140 | -2,000 | -222 | 17,830 | ||||
| 2015-08-21 | 2015-08-20 | 4 | AGARWAL SUNIL | RARE | Common Stock | D | 110.3961 | -4,875 | -538 | 19,830 | ||||
| 2015-08-21 | 2015-08-20 | 4 | AGARWAL SUNIL | RARE | Common Stock | D | 108.9801 | -1,471 | -160 | 24,705 | ||||
| 2015-08-21 | 2015-08-20 | 4 | AGARWAL SUNIL | RARE | Common Stock | D | 107.3020 | -724 | -78 | 26,176 | ||||
| 2015-08-21 | 2015-08-20 | 4 | AGARWAL SUNIL | RARE | Common Stock | D | 55.8800 | 10,000 | 559 | 26,900 | ||||
| 2015-08-21 | 2015-08-20 | 4 | AGARWAL SUNIL | RARE | Common Stock | D | 112.7284 | -3,650 | -411 | 16,900 | ||||
| 2015-08-21 | 2015-08-20 | 4 | AGARWAL SUNIL | RARE | Common Stock | D | 112.1892 | -3,370 | -378 | 20,550 | ||||
| 2015-08-21 | 2015-08-19 | 4 | AGARWAL SUNIL | RARE | Common Stock | D | 116.9900 | -5,480 | -641 | 23,920 | ||||
| 2015-08-14 | 2015-08-12 | 4 | Kassberg Thomas Richard | RARE | Common Stock | D | 109.7000 | -3,334 | -366 | 70,204 | ||||
| 2015-08-06 | 2015-08-04 | 4 | Dallas Jayson Donald Alexander | RARE | Stock Option (Right to Buy) | D | 116.45 | 90,000 | 90,000 | |||||
| 2015-08-06 | 2015-08-04 | 4 | Dallas Jayson Donald Alexander | RARE | Common Stock | D | 10,000 | 10,000 | ||||||
| 2015-07-22 | 2015-07-20 | 4 | Sharp Shalini | RARE | Common Stock | D | 130.9900 | -488 | -64 | 41,801 | ||||
| 2015-07-22 | 2015-07-20 | 4 | Sharp Shalini | RARE | Common Stock | D | 131.5600 | -1,412 | -186 | 42,289 | ||||
| 2015-07-22 | 2015-07-20 | 4 | Sharp Shalini | RARE | Common Stock | D | 132.4700 | -1,954 | -259 | 43,701 | ||||
| 2015-07-22 | 2015-07-20 | 4 | Sharp Shalini | RARE | Common Stock | D | 130.9900 | -488 | -64 | 41,801 | ||||
| 2015-07-22 | 2015-07-20 | 4 | Sharp Shalini | RARE | Common Stock | D | 131.5600 | -1,412 | -186 | 42,289 | ||||
| 2015-07-22 | 2015-07-20 | 4 | Sharp Shalini | RARE | Common Stock | D | 132.4700 | -1,954 | -259 | 43,701 | ||||
| 2015-07-20 | 2015-07-16 | 4 | Pinion John Richard | RARE | Stock Option (Right to Buy) | D | 124.87 | 90,000 | 90,000 | |||||
| 2015-07-20 | 2015-07-16 | 4 | Pinion John Richard | RARE | Common Stock | D | 7,500 | 7,500 | ||||||
| 2015-07-20 | 2015-07-16 | 4 | Huang Dennis Karl | RARE | Stock Option (Right to Buy) | D | 124.87 | 15,000 | 15,000 | |||||
| 2015-07-10 | 2015-07-08 | 4 | Kassberg Thomas Richard | RARE | Common Stock | D | 102.1200 | -3,334 | -340 | 73,538 | ||||
| 2015-06-22 | 2015-06-18 | 4 | Fust Matthew K | RARE | Stock Option (Right to Buy) | D | 97.85 | 7,500 | 7,500 | |||||
| 2015-06-22 | 2015-06-18 | 4 | SIEGALL CLAY B | RARE | Stock Option (Right to Buy) | D | 97.85 | 7,500 | 7,500 | |||||
| 2015-06-22 | 2015-06-18 | 4 | NARACHI MICHAEL | RARE | Stock Option (Right to Buy) | D | 97.85 | 7,500 | 7,500 | |||||
| 2015-06-22 | 2015-06-18 | 4 | WELCH DANIEL G | RARE | Stock Option (Right to Buy) | D | 97.85 | 7,500 | 7,500 | |||||
| 2015-06-22 | 2015-06-18 | 4 | Aliski William | RARE | Stock Option (Right to Buy) | D | 97.85 | 7,500 | 7,500 | |||||
| 2015-06-19 | 2015-06-18 | 4 | Sharp Shalini | RARE | Common Stock | D | 96.3500 | -1,349 | -130 | 45,655 | ||||
| 2015-06-19 | 2015-06-18 | 4 | Sharp Shalini | RARE | Common Stock | D | 95.9500 | -2,651 | -254 | 47,004 | ||||
| 2015-06-19 | 2015-06-17 | 4 | Huizenga Theodore Alan | RARE | Stock Option (Right to Buy) | D | 21.00 | -1,500 | 0 | |||||
| 2015-06-19 | 2015-06-17 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 94.8000 | -1,500 | -142 | 2,500 | ||||
| 2015-06-19 | 2015-06-17 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 21.0000 | 1,500 | 32 | 4,000 | ||||
| 2015-06-12 | 2015-06-10 | 4 | Kassberg Thomas Richard | RARE | Common Stock | D | 88.1900 | -3,334 | -294 | 76,872 | ||||
| 2015-05-27 | 2015-05-21 | 4 | Kassberg Thomas Richard | RARE | Stock Option (Right to Buy) | D | 84.89 | 26,300 | 26,300 | |||||
| 2015-05-27 | 2015-05-21 | 4 | Kassberg Thomas Richard | RARE | Common Stock | D | 4,400 | 80,206 | ||||||
| 2015-05-27 | 2015-05-21 | 4 | KAKKIS EMIL D | RARE | Stock Option (Right to Buy) | D | 84.89 | 68,300 | 68,300 | |||||
| 2015-05-27 | 2015-05-21 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 11,400 | 635,640 | ||||||
| 2015-05-27 | 2015-05-21 | 4 | Sharp Shalini | RARE | Stock Option (Right to Buy) | D | 84.89 | 26,300 | 26,300 | |||||
| 2015-05-27 | 2015-05-21 | 4 | Sharp Shalini | RARE | Common Stock | D | 4,400 | 49,655 | ||||||
| 2015-05-27 | 2015-05-21 | 4 | Huizenga Theodore Alan | RARE | Stock Option (Right to Buy) | D | 84.89 | 10,700 | 10,700 | |||||
| 2015-05-27 | 2015-05-21 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 1,800 | 4,300 | ||||||
| 2015-05-27 | 2015-05-21 | 4 | AGARWAL SUNIL | RARE | Stock Option (Right to Buy) | D | 84.89 | 26,300 | 26,300 | |||||
| 2015-05-27 | 2015-05-21 | 4 | AGARWAL SUNIL | RARE | Common Stock | D | 4,400 | 29,400 | ||||||
| 2015-05-20 | 2015-05-18 | 4 | Sharp Shalini | RARE | Common Stock | D | 79.4300 | -4,000 | -318 | 45,255 | ||||
| 2015-05-15 | 2015-05-13 | 4 | Kassberg Thomas Richard | RARE | Common Stock | D | 72.0400 | -3,334 | -240 | 75,806 | ||||
| 2015-05-07 | 2015-05-05 | 4 | Huang Dennis Karl | RARE | Stock Option (Right to Buy) | D | 62.63 | 60,000 | 60,000 | |||||
| 2015-05-07 | 2015-05-05 | 4 | Huang Dennis Karl | RARE | Common Stock | D | 7,500 | 7,500 | ||||||
| 2015-05-05 | 2015-05-01 | 4 | Sharp Shalini | RARE | Stock Option (Right to Buy) | D | 0.82 | -1,000 | 110,663 | |||||
| 2015-05-05 | 2015-05-01 | 4 | Sharp Shalini | RARE | Common Stock | D | 0.8150 | 1,000 | 1 | 49,255 | ||||
| 2015-04-22 | 2015-04-20 | 4 | Sharp Shalini | RARE | Common Stock | D | 62.5900 | -3,000 | -188 | 48,255 | ||||
| 2015-04-22 | 2015-04-20 | 4 | Sharp Shalini | RARE | Common Stock | D | 61.1400 | -1,000 | -61 | 51,255 | ||||
| 2015-04-10 | 2015-04-08 | 4 | WELCH DANIEL G | RARE | Stock Option (Right to Buy) | D | 59.95 | 17,500 | 17,500 | |||||
| 2015-04-10 | 2015-04-08 | 4 | Kassberg Thomas Richard | RARE | Common Stock | D | 58.0200 | -3,333 | -193 | 79,140 | ||||
| 2015-03-23 | 2015-03-19 | 4 | Fust Matthew K | RARE | Stock Option (Right to Buy) | D | 21.00 | -6,319 | 11,181 | |||||
| 2015-03-23 | 2015-03-19 | 4 | Fust Matthew K | RARE | Common Stock | D | 21.0000 | 6,319 | 133 | 11,319 | ||||
| 2015-03-20 | 2015-03-18 | 4 | Sharp Shalini | RARE | Common Stock | D | 61.4500 | -4,000 | -246 | 52,255 | ||||
| 2015-03-13 | 2015-03-11 | 4 | Kassberg Thomas Richard | RARE | Common Stock | D | 56.3000 | -3,333 | -188 | 82,473 | ||||
| 2015-03-05 | 2015-03-03 | 4 | Huizenga Theodore Alan | RARE | Stock Option (Right to Buy) | D | 21.00 | -2,500 | 29,403 | |||||
| 2015-03-05 | 2015-03-03 | 4 | Huizenga Theodore Alan | RARE | Common Stock | D | 21.0000 | 2,500 | 52 | 2,500 | ||||
| 2015-02-24 | 2015-02-20 | 4 | NARACHI MICHAEL | RARE | Stock Option (Right to Buy) | D | 55.57 | 17,500 | 17,500 | |||||
| 2015-02-20 | 2015-02-18 | 4 | Sharp Shalini | RARE | Common Stock | D | 53.9253 | -3,704 | -200 | 56,255 | ||||
| 2015-02-20 | 2015-02-18 | 4 | Sharp Shalini | RARE | Common Stock | D | 54.7168 | -296 | -16 | 59,959 | ||||
| 2015-02-13 | 2015-02-11 | 4 | Kassberg Thomas Richard | RARE | Common Stock | D | 54.3117 | -3,333 | -181 | 85,806 | ||||
| 2015-01-22 | 2015-01-20 | 4 | Sharp Shalini | RARE | Common Stock | D | 51.2393 | -4,000 | -205 | 60,255 | ||||
| 2015-01-16 | 2015-01-14 | 4 | Kassberg Thomas Richard | RARE | Common Stock | D | 51.5100 | -3,333 | -172 | 89,139 | ||||
| 2014-12-22 | 2014-12-18 | 4 | Sharp Shalini | RARE | Common Stock | D | 44.8224 | -4,000 | -179 | 64,255 | ||||
| 2014-12-12 | 2014-12-10 | 4 | Kassberg Thomas Richard | RARE | Common Stock | D | 40.2200 | -3,333 | -134 | 92,472 | ||||
| 2014-12-08 | 2014-12-04 | 4 | Aliski William | RARE | Common Stock | D | 42.4616 | -3,109 | -132 | 60,010 | ||||
| 2014-12-08 | 2014-12-04 | 4 | Aliski William | RARE | Common Stock | D | 41.8295 | -2,891 | -121 | 63,119 | ||||
| 2014-11-21 | 2014-11-20 | 4 | Sharp Shalini | RARE | Common Stock | D | 44.0703 | -4,000 | -176 | 68,255 | ||||
| 2014-11-14 | 2014-11-12 | 4 | Kassberg Thomas Richard | RARE | Common Stock | D | 41.8500 | -3,333 | -139 | 95,805 | ||||
| 2014-10-22 | 2014-10-20 | 4 | Aliski William | RARE | Warrant to Purchase Common Stock (Right to Buy) | D | 3.01 | -29,108 | 0 | |||||
| 2014-10-22 | 2014-10-20 | 4 | Aliski William | RARE | Common Stock | D | 3.0100 | 29,108 | 88 | 66,010 | ||||
| 2014-10-22 | 2014-10-20 | 4 | Sharp Shalini | RARE | Common Stock | D | 46.0200 | -4,000 | -184 | 72,255 | ||||
| 2014-10-10 | 2014-10-08 | 4 | Kassberg Thomas Richard | RARE | Common Stock | D | 53.2600 | -3,333 | -178 | 99,138 | ||||
| 2014-09-19 | 2014-09-18 | 4 | Sharp Shalini | RARE | Common Stock | D | 56.0000 | -4,000 | -224 | 76,255 | ||||
| 2014-09-12 | 2014-09-10 | 4 | Kassberg Thomas Richard | RARE | Common Stock | D | 54.8200 | -3,333 | -183 | 102,471 | ||||
| 2014-09-04 | 2014-09-03 | 4 | Kassberg Thomas Richard | RARE | Common Stock | D | 55.0000 | -10,000 | -550 | 105,804 | ||||
| 2014-09-04 | 2014-09-02 | 4 | Kassberg Thomas Richard | RARE | Common Stock | D | 52.8200 | -10,000 | -528 | 115,804 | ||||
| 2014-08-21 | 2014-08-19 | 4 | AGARWAL SUNIL | RARE | Stock Option (Right to Buy) | D | 55.88 | 150,000 | 150,000 | |||||
| 2014-08-21 | 2014-08-19 | 4 | AGARWAL SUNIL | RARE | Common Stock | D | 25,000 | 25,000 | ||||||
| 2014-08-19 | 2014-08-18 | 4 | Sharp Shalini | RARE | Common Stock | D | 53.9700 | -4,000 | -216 | 80,255 | ||||
| 2014-08-05 | 2014-08-01 | 4 | FMR LLC / Fidelity Management & Research | RARE | Common Stock | I | -1,802,246 | 1,457,994 | ||||||
| 2014-07-17 | 2014-07-10 | 4 | SIEGALL CLAY B | RARE | Stock Option (Right to Buy) | D | 40.37 | 7,500 | 7,500 | |||||
| 2014-07-17 | 2014-07-10 | 4 | Fust Matthew K | RARE | Stock Option (Right to Buy) | D | 40.37 | 7,500 | 7,500 | |||||
| 2014-07-17 | 2014-07-10 | 4 | Nadav Eran | RARE | Stock Option (Right to Buy) | D | 40.37 | 7,500 | 7,500 | |||||
| 2014-07-17 | 2014-07-10 | 4 | Aliski William | RARE | Stock Option (Right to Buy) | D | 40.37 | 7,500 | 7,500 | |||||
| 2014-07-14 | 2014-07-14 | 4 | TPG Group Holdings (SBS) Advisors, Inc. See Explanation of Responses | RARE | Common Stock | I | 37.6000 | -488,820 | -18,380 | 2,596,420 | ||||
| 2014-03-28 | 2014-02-05 | 4/A | KAKKIS EMIL D | RARE | Warrant to Purchase Common Stock (Right to Buy) | D | 3.01 | 83,167 | 0 | |||||
| 2014-03-28 | 2014-02-05 | 4/A | KAKKIS EMIL D | RARE | Warrant to Purchase Series A Preferred Stock (Right to Buy) | D | 0.96 | -260,688 | 0 | |||||
| 2014-02-11 | 2014-02-05 | 4 | Kassberg Thomas Richard | RARE | Series A Preferred Stock | D | -98,595 | 0 | ||||||
| 2014-02-11 | 2014-02-05 | 4 | Kassberg Thomas Richard | RARE | Common Stock | D | 31,454 | 125,804 | ||||||
| 2014-02-07 | 2014-02-05 | 4 | KAKKIS EMIL D | RARE | Warrant to Purchase Common Stock (Right to Buy) | D | 3.01 | 41,583 | 0 | |||||
| 2014-02-07 | 2014-02-05 | 4 | KAKKIS EMIL D | RARE | Warrant to Purchase Series A Preferred Stock (Right to Buy) | D | 0.96 | -130,344 | 0 | |||||
| 2014-02-07 | 2014-02-05 | 4 | KAKKIS EMIL D | RARE | Warrant to Purchase Common Stock (Right to Buy) | D | 3.01 | 24,950 | 0 | |||||
| 2014-02-07 | 2014-02-05 | 4 | KAKKIS EMIL D | RARE | Warrant to Purchase Series A Preferred Stock (Right to Buy) | D | 0.96 | -78 | 0 | |||||
| 2014-02-07 | 2014-02-05 | 4 | KAKKIS EMIL D | RARE | Warrant to Purchase Common Stock (Right to Buy) | D | 3.01 | 83,039 | 0 | |||||
| 2014-02-07 | 2014-02-05 | 4 | KAKKIS EMIL D | RARE | Warrant to Purchase Series A Preferred Stock (Right to Buy) | D | 0.96 | -260,688 | 0 | |||||
| 2014-02-07 | 2014-02-05 | 4 | KAKKIS EMIL D | RARE | Series A Preferred Stock | D | -1,956,686 | 0 | ||||||
| 2014-02-07 | 2014-02-05 | 4 | KAKKIS EMIL D | RARE | Common Stock | D | 624,240 | 624,240 | ||||||
| 2014-02-07 | 2014-02-05 | 4 | Aliski William | RARE | Warrant to Purchase Common Stock (Right to Buy) | D | 3.01 | 29,108 | 0 | |||||
| 2014-02-07 | 2014-02-05 | 4 | Aliski William | RARE | Warrant to Purchase Series A Preferred Stock (Right to Buy) | D | 0.96 | -91,241 | 0 | |||||
| 2014-02-07 | 2014-02-05 | 4 | TPG Group Holdings (SBS) Advisors, Inc. See Explanation of Responses | RARE | Series B Preferred Stock | I | -541,634 | 0 | ||||||
| 2014-02-07 | 2014-02-05 | 4 | TPG Group Holdings (SBS) Advisors, Inc. See Explanation of Responses | RARE | Series A Preferred Stock | I | -9,129,063 | 0 | ||||||
| 2014-02-07 | 2014-02-05 | 4 | TPG Group Holdings (SBS) Advisors, Inc. See Explanation of Responses | RARE | Common Stock | I | 3,085,240 | 3,085,240 | ||||||
| 2014-02-05 | 2014-01-31 | 4 | FMR LLC / Fidelity Management & Research by Beacon Bioventures Fund II Limited Partnership | RARE | Common Stock | I | 21.0000 | 175,000 | 3,675 | 3,260,240 | ||||
| 2014-02-05 | 2014-01-30 | 4 | FMR LLC / Fidelity Management & Research by Beacon Bioventures Fund II Limited Partnership | RARE | Series B Convertible Preferred Stock | I | -541,634 | 0 | ||||||
| 2014-02-05 | 2014-01-30 | 4 | FMR LLC / Fidelity Management & Research by Beacon Bioventures Fund II Limited Partnership | RARE | Series A Convertible Preferred Stock | I | -9,129,063 | 0 | ||||||
| 2014-02-05 | 2014-01-30 | 4 | FMR LLC / Fidelity Management & Research by Beacon Bioventures Fund II Limited Partnership | RARE | Common Stock | I | 172,797 | 3,085,240 | ||||||
| 2014-02-05 | 2014-01-30 | 4 | FMR LLC / Fidelity Management & Research by Beacon Bioventures Fund II Limited Partnership | RARE | Common Stock | I | 2,912,443 | 2,912,443 | ||||||
| 2014-02-03 | 2014-01-30 | 4 | SIEGALL CLAY B | RARE | Stock Option (Right to Buy) | D | 21.00 | 17,500 | 17,500 | |||||
| 2014-02-03 | 2014-01-30 | 4 | Kassberg Thomas Richard | RARE | Common Stock | D | 21.0000 | 1,500 | 32 | 94,350 | ||||
| 2014-02-03 | 2014-01-30 | 4 | Fust Matthew K | RARE | Stock Option (Right to Buy) | D | 21.00 | 17,500 | 17,500 | |||||
| 2014-02-03 | 2014-01-30 | 4 | Fust Matthew K | RARE | Common Stock | D | 21.0000 | 5,000 | 105 | 5,000 | ||||
| 2014-02-03 | 2014-01-30 | 4 | Sharp Shalini | RARE | Common Stock | D | 21.0000 | 4,500 | 94 | 84,255 | ||||
| 2014-02-03 | 2014-01-30 | 4 | Nadav Eran | RARE | Stock Opton (Right to Buy) | D | 21.00 | 17,500 | 17,500 | |||||
| 2014-02-03 | 2014-01-30 | 4 | Steen Marten | RARE | Stock Option (Right to Buy) | D | 21.00 | 17,500 | 17,500 | |||||
| 2014-02-03 | 2014-01-30 | 4 | Aliski William | RARE | Stock Option (Right to Buy) | D | 21.00 | 17,500 | 17,500 | |||||
| 2014-02-03 | 2014-01-30 | 4 | Aliski William | RARE | Common Stock | D | 21.0000 | 5,000 | 105 | 36,903 | ||||
| 2014-01-30 | 3 | Kassberg Thomas Richard | RARE | Common Stock | D | 92,850 | ||||||||
| 2014-01-30 | 3 | KAKKIS EMIL D By Emil Kakkis and Jenny Soriano Living Trust, Dated June 18, 2009 | RARE | Common Stock | I | 2,552,241 | ||||||||
| 2014-01-30 | 3 | Sharp Shalini | RARE | Common Stock | D | 79,755 | ||||||||
| 2014-01-30 | 3 | Nadav Eran | RARE | No securities beneficially owned | D | 0 | ||||||||
| 2014-01-30 | 3 | Aliski William | RARE | Common Stock | D | 31,903 |
P
Pembelian sekuritas non-derivatif atau derivatif di pasar terbuka atau secara pribadi.
S
Penjualan terbuka atau penjualan pribadi atas sekuritas non-derivatif atau derivatif.
A
Hibah, penghargaan, atau perolehan sekuritas lainnya dari perusahaan (seperti opsi)
C
Konversi turunan
D
Penjualan atau pengalihan sekuritas kembali ke perusahaan.
F
Pembayaran harga pelaksanaan atau kewajiban pajak menggunakan sebagian sekuritas yang diterima dari perusahaan.
G
Pemberian sekuritas oleh atau kepada orang dalam.
K
Swap ekuitas dan transaksi lindung nilai serupa
M
Pelaksanaan atau konversi sekuritas derivatif yang diterima dari perusahaan (seperti opsi)
V
Transaksi yang dilaporkan secara sukarela pada Formulir 4.
J
Lainnya (disertai dengan catatan kaki yang menjelaskan transaksi tersebut)
